Infection Biology

Infection Biology requires multidisciplinary experts that think two steps ahead

We study commensal and pathogenic intestinal bacteria and their interactions with the human or animal host. Our main goal is to provide mechanistic insights into host-microbe interactions in the intestine that lead the way for the development of novel therapeutic intervention strategies.

Bacterial Virulence and Innate Immunity
Bacterial pathogens have evolved smart strategies to cause infections. We try to understand the molecular crosstalk between pathogens and the mucosal host defense to develop novel vaccines. Read more

Bacterial Adaptation Mechanisms 
Bacteria are extremely good at adapting to their constantly changing physical and chemical environment. We investigate how they do that in and outside their host. Read more 

Innate Immune Defense Mechanisms
The intestinal mucus layer separates trillions of commensal and pathogenic microbiota from the host epithelial lining. We investigate innate immune defense at this fascinating host-microbe interfase. Read more

Microbiota-Host Interactions in the Intestine
The intestinal microbiota plays a key role in the development of several diseases including inflammatory bowel disease, colorectal cancer, diabetes and metabolic syndrome. We try to reveal and characterise these intestinal bacteria, to understand the molecular mechanisms behind pathological host-microbiota interactions, and to develop and test putative therapeutic approaches. Read more