Alternative and in vitro models in toxicology
The use of laboratory animals is becoming less and less accepted by society
How great would it be if we could assess the safety of chemicals and pharmaceuticals without the use of laboratory animals? To be able to test the safety of chemicals solely based on human physiology and biology, including such vulnerable groups as infants, the elderly or the sick?
Utrecht University plays a leading role in the Netherlands concerning the use of alternatives to laboratory animals. According to Juliette Legler, Professor of Toxicology, the current system of assessing the safety of chemicals and pharmaceuticals based on animal testing is outdated: "It is slow and leaves little room for innovation. Developments in biotechnology are proceeding very rapidly, and our current system of safety assessment is unnecessarily slowing us down if we don’t keep up with the innovations."
Utrecht researchers show that the transition to innovative and societally relevant science and policy is possible without animal testing.
Animal-Free Assays for endocrine disruption – from science to Regulatory Acceptance
Researchers from UU and RIVM study challenges and opportunities within existing legal and regulatory frameworks for the use of animal-free models for identification of endocrine disrupting chemicals. This is done by combining expertise from natural sciences, social sciences and humanities with key public sector expertise.