We stimulate the 3Rs of Replacement, Reduction and Refinement - in that order

To reduce the use of laboratory animals in research and education, the 3Rs Centre Utrecht (3RCU) stimulates the 3Rs of Replacement, Reduction and Refinement – in that order. This website provides centralised information about the 3Rs and access to 3Rs tools. Additionally, you can find information about initiatives of the 3RCU. Our philosophy can be summarized as ‘ideas supported by data’, and we facilitate many targeted actions. Read more about our mission.

  • Replacement & NAMs The R for Replacement encompasses initiatives that focus on the direct replacement of laboratory animals with animal-free alternatives.
  • Reduction & Refinement The R of Reduction focuses on reducing the number of animals used per experiment. The R of Refinement focuses on everything that can reduce the 'discomfort' of laboratory animals.
  • Tools The 3RCU hosts a central hub for 3Rs tools, both for educational and research applications.
  • Projects Overview In order to support our mission, we are actively involved in a variety of projects centred around advancing the principles of the 3Rs.

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Some of the images used on the 3RS website were generated with the assistance of AI.