We stimulate the 3Rs of Replacement, Reduction and Refinement - in that order

To reduce the use of laboratory animals in research and education, the 3Rs Centre Utrecht (3RCU) stimulates the 3Rs of Replacement, Reduction and Refinement – in that order. This website provides centralised information about the 3Rs and access to 3Rs tools. Additionally, you can find information about initiatives of the 3RCU. Our philosophy can be summarized as ‘ideas supported by data’, and we facilitate many targeted actions. Read more about our mission.

  • Events

    • WC13-2025 for Advancing the 3Rs and Alternative Methods in Rio de Janeiro

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      WC13-2025, hosted in Rio de Janeiro, Brazil, on August 31- Spetmber 4, 2025, celebrates the country's leadership in advancing alternative methods and the 3Rs. With deep roots in initiatives like the creation of Arouca’s Law, the establishment of BraCVAM, and previous Latin American congresses, the event will bring together global experts to discuss the latest advancements, foster collaboration, and highlight Brazil’s pivotal contributions to the field.
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Some of the images used on the 3RS website were generated with the assistance of AI.