The Bijvoet Centre studies life on the molecular scale. Our focus is on the biomolecules that make up all living organisms, including humans. We concentrate on elucidating the structure of these biomolecules, such as proteins, at the atomic level and on determining the relation between their structure and function in living cells and tissues. By working on healthy cells and those affected by disease, we aim to unravel the basic mechanisms of disease origin. To study the structure of biomolecules, we have a wide range of technologies at our disposal, including advanced biochemistry and biophysics, NMR, X-ray crystallography, electron microscopy and mass spectrometry.