Group leaders

The use of chemical proteomics strategies to study protein lipidation and small molecule - drug interactions

We develop and apply magnetic resonance-based approaches to unravel complex molecular systems in vitr0, in situ & in vivo.

The computational structural biology group develops bioinformatics and computational approaches to predict and model biomolecular interactions at atomic level.

Research interest focuses on the synthesis and biological functions of carbohydrates and glycoconjugates

Masters Coordinator Bioinformatics and Biocomplexity; UIPS DI PhD programme coordinator; Bioinformatics in the field of Proteomics Research

The lab innovates cryo-EM approaches to study the biogenesis and quality control of proteins at cellular membranes

Understanding of molecular mechanisms based on 3D protein structures by cryo-EM and crystallography

Research interests are in technology development for proteomics and mass spectrometry applied to immunology and pharmaceutics

We use correlative light and electron microscopy to study cellular stress responses and cytoskeleton structures.

The van Ingen team uses modern NMR methods to investigate the molecular basis of chromatin function

The Janssen lab uses structural biology, biophysical and cellular techniques to disentangle intercellular signaling and adhesion mechanisms in our tissues.

Model membrane systems and lipid/protein interactions

We investigate the mechanisms governing membrane lipid homeostasis in the reference eukaryote S. cerevisiae.

Crystal structure determinations of small-molecular and macromolecular compounds

Glycoproteomics and glycoprotein analysis

Protein damage control: new molecular strategies for protein aggregation diseases such as Alzheimer or Huntington, exploiting the cellular chaperone machinery

The Scheltema lab develops structural proteomics techniques and applies them to uncover structural details for protein complexes relevant to health&disease.

My lab studies the molecular mechanisms of protein aggregation in vivo using the model organism C. elegans

We study virus-host interactions with structural proteomics techniques

My research applies innovative mass spectrometry approaches to understand protein regulation in cancer, with a focus on immune-tumor cell signaling

Cellular structural biology of fertilization: our group combines cryo-electron microscopy with light microcopy to unravel the molecular basis of fertilization