Research group of Dr. Loes Kroon-Batenburg
The research of dr. Loes Kroon-Batenburg focusses on the development of methods for accurate integration of diffraction data.
All methods are implemented in the software suite EVAL. Recently we started working on data collection and data processing of less orderedly packed crystals. Such crystals give rise to diffuse scattering. We will develop measurement strategies and algorithms for data processing and interpretation of the diffuse scattering and for computing diffuse scattering from protein crystal structures. The diffuse scattering of crystals in between Bragg peaks is commonly ignored. However, these intensities are affected by so-called thermal diffuse scattering. Therefore, even the derived average structure is not fully accurate. She is working towards probing internal dynamics of macromolecules from the diffuse scattering.