Selected publications

  1. Leung M.R., Zeng J., Wang X., Roelofs M.C., Huang W., Zenezini Chiozzi R., Hevler J.F., Heck A.J.R., Dutcher S.K., Brown A., Zhang R., Zeev-Ben-Mordehai T.. Structural specializations of the sperm tail. 2023 Cell. 86(13):2880-2896.e17
  2. Leung, M. R., Ravi, R. T., Gadella, B. M., & Zeev-Ben-Mordehai, T. Membrane Remodeling and Matrix Dispersal Intermediates During Mammalian Acrosomal Exocytosis. 2021 Frontiers in Cell and Developmental Biology, 9, 1-13. [765673]. 
  3. Leung M. R., Zenezini-Chiozzi R., Roelofs M. C., Hevler J. F., Ravi, R. T., Maitan P., Zhang M., Henning H., Bromfield E.G., Howes S. C., Gadella B. M.,Heck A. J. R., Zeev-Ben-Mordehai T. In-cell structures of a conserved supramolecular array at the mitochondria-cytoskeleton interface in mammalian sperm. 2021. Proc Natl Acad Sci U S A. 118(45) e2110996118.
  4. Khanal S., Leung M. R., Royfman A., Fishman E. L., Saltzman B., Bloomfield-Gadêlha H., Zeev-Ben-Mordehai T., and Avidor-Reiss T. A dynamic basal complex modulates mammalian sperm movement. 2021. Nature Communications. 12:3808. 

  5. Leung M. R., Roelofs M. C., Ravi R. T., Maitan P., Zhang M., Henning H., Bromfield E.G., Howes S. C., Gadella B. M., Bloomfield-gadêlha H., Zeev-Ben-Mordehai T. The multi-scale architecture of mammalian sperm flagella and implications for ciliary motility. 2021. EMBO J. 40:e107410. 

  6. Ravi R. T., M. R. Leung, T. Zeev-Ben-Mordehai. Looking back and looking forward: contributions of electron microscopy to the structural cell biology of gametes and fertilisation. 2020. Open Biol. 10:200186. 

  7. Leung, M. R., L. S. van Bezouwen, L. M. Schopfer, J. L. Sussman, I. Silman, O. Lockridge, T. Zeev-Ben-Mordehai. Cryo-EM structure of the native butyrylcholinesterase tetramer reveals a dimer of dimers stabilized by a superhelical assembly. 2018. PNAS. 115:13270-13275.
  8. Chorev, D.S., L. A. Baker, D. Wu, V. Beilsten-Edmands, S. L. Rouse, T. Zeev-Ben-Mordehai, C. Jiko, F. Samsudin, C. Gerle, S. Khalid, A. G. Stewart, S. J. Matthews, K. Grünewald, C. V. Robinson. Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry. 2018. Science. 362:829-834.
  9. Zeng, X., M. Leung, T. Zeev-Ben-Mordehai, M. Xu. A convolutional autoencoder approach for mining features in cellular electron cryo-tomograms and weakly supervised coarse segmentation. 2017. J. Stru. Biol. 202:150-160
  10. Xu, M., X. Chai, H. Muthakana, X. Liang, G. Yang, T. Zeev-Ben-Mordehai, E. Xing. Deep learning-based subdivision approach for large scale macromolecules structure recovery from electron cryo tomograms. 2017. Bioinformatics. 33, i13–i22
  11. Zeev-Ben-Mordehai, T., D. Vasishtan, A. Hernández Durán, P. White, A. Prasad Pandurangan, C.A. Siebert, M. Topf and K. Grünewald. 2016. Two distinct trimeric conformations of natively membrane-anchored full-length herpes simplex virus 1 glycoprotein B. PNAS. 113, 4176–4181
  12. §Hagen, C., §K.C. Dent, §T. Zeev-Ben-Mordehai, §M. Grange, §J.B. Bosse, C. Whittle, B.G. Klupp, C.A. Siebert, D. Vasishtan, F.J.B. Bäuerlein, J. Cheleski, S. Werner, P. Guttmann, S. Rehbein, K. Henzler, J. Demmerle, B. Adler, U. Koszinowski, L. Schermelleh, G. Schneider, L.W. Enquist, J.M. Plitzko, T.C. Mettenleiter and K. Grünewald. 2015. Structural basis of vesicle formation at the inner nuclear membrane. Cell. 163:1692-1701
  13. §Zeev-Ben-Mordehai, T., §M. Weberruß, §M. Lorenz, §J. Cheleski, §T. Hellberg, C. Whittle, K. El-Omari, D. Vasishtan, K. C. Dent, K. Harlos, C. Hagen, K. Franzke, B. G. Klupp, W. Antonin, T. C. Mettenleiter and K. Grünewald. 2015. Crystal structure of the herpesvirus nuclear egress complex provides insights into inner nuclear membrane remodelling. Cell Reports. 13:1-8 
  14. Zeev-Ben-Mordehai, T., D. Vasishtan, C.A. Siebert, C. Whittle and K. Grünewald. 2014. Extracellular vesicles: a platform for structure determination of membrane proteins by cryoEM. Structure. 22: 1687-1692
  15. Zeev-Ben-Mordehai, T., D. Vasishtan, C.A. Siebert and K. Grünewald. 2014. The full-length cell-cell fusogen EFF-1 is monomeric and upright on the membrane. Nature Communications. 5: 3912
  16. Zeev-Ben-Mordehai, T., C. Hagen and K. Grünewald. 2014. A cool hybrid approach to the herpesvirus 'life' cycle. Current Opinion in Virology. 5C: 42-49
  17. §Maurer, U. E., §T. Zeev-Ben-Mordehai, A. P. Pandurangan, T. M. Cairns, B. P. Hannah, J. C. Whitbeck, R. J. Eisenberg, G. H. Cohen, M. Topf, J. T. Huiskonen and K. Grünewald. 2013. The structure of herpesvirus fusion glycoprotein B-bilayer complex reveals the protein-membrane and lateral protein-protein interaction. Structure. 21: 1396-1405
  18. Avinoam, O., K. Fridman, C. Valansi, I. Abutbul, T. Zeev-Ben-Mordehai, U. Maurer, U. A. Sapir, D. Danino, K. Grünewald, J. M. White, B. Podbilewicz. 2011. Conserved eukaryotic fusogens can fuse viral envelopes to cells. Science. 332: 589-592
  19. Zeev-Ben-Mordehai, T., E. Mylonas, A. Paz, Y. Peleg, L. Toker, I. Silman, D.I. Svergun, J.L. Sussman. 2009. The quaternary structure of amalgam, a Drosophila neuronal adhesion protein, explains its dual adhesion properties. Biophysical Journal. 97: 2316-2326