Department of Chemistry

Professor dr. A.J.R. (Albert) Heck

Research work of the Heck group focuses on the development and implementation of innovative mass spectrometric methods for the more efficient and detailed characterization of proteins in relation to their biological function. 

The Heck group has world-renowned expertise in the analysis of protein-ligand, protein-protein and protein-DNA analysis by mass spectrometry.  The facility is also hosted by the group at the Bijvoet Center for Biomolecular Research.

The facility coordinates the EU funded, EPIC-XS project, launched in 2019, providing access to leading proteomics facilities and research groups in Europe.

 

Professor dr. F.G. (Friedrich) Förster

Research work involves the in situ study of associated lipid membranes and transient macromolecular complexes, using cryo-electron microscopy techniques, protein-protein interactions, and computational modeling. 

The electron microscopy facility (EM Square), hosted by the Cryo-EM group, is devoted to the development and application of technologies for (cryo) specimen preparation, 3D (cryo) electron microscopy data collection, as well as image analysis for cell biology and material sciences applications. The facility is also hosted by the group at the Bijvoet Center for Biomolecular Research.

Professor dr. M. (Marc) Baldus

Research work is focused on the development of NMR-based approaches, targeting such molecular arrangements by combining recent advancements in solid-state NMR to enhance spectroscopic sensitivity and resolution with dedicated biochemical and biophysical and cell-biology techniques.

The SON NMR Large-Scale Facility is hosted by the NMR Spectroscopy group of the Bijvoet Center for Biomolecular Research.

Professor dr. P. (Piet) Gros

Research work uses protein crystallography to study bio-molecular recognition and regulation processes with emphasis on bio-medically important proteins, in particular in the area of infection and immunity. The X-ray crystallography facility is hosted by the crystal and structural chemistry group of the Bijvoet Center for Biomolecular Research.

Assistant professor Tzviya Zeev-Ben-Mordehai

Research work as a principal investiogaor at the cryo Electron Microscopy group, focuses on the mechanism of action of fusogens, i.e., proteins mediating biological membrane fusion.

Professor dr. C.R. (Celia) Berkers

Research work is focused on studying the small molecule metabolite profile of cells using Mass Spectrometry – with biochemical and chemical biology techniques.