Department of Biology
Research work involves the control of growth factor signaling. The group studies the regulatory mechanism of receptor internalization and trafficking in live cells using advanced light microscopical techniques.
The nanobody facility can select nanobodies (antibody fragments,15 kDa) that bind to any possible target using phage display technology. The facility is also experienced in further functionalization of the nanobodies using different conjugation strategies including sortase tagging and click-chemistry.
Research group focuses on studying the mechanism of action of fusogens, i.e., proteins mediating biological membrane fusion. She is applying a hybrid structural approach using electron cryo microscopy and tomography as core techniques and complemented with super-resolution fluorescence microscopy, crystallography and protein biophysics.