1. Rahimian S, Kleinovink JW, Fransen MF, Mezzanotte L, Gold H, Wisse P, Overkleeft H, Amidi M, Jiskoot W, Löwik CW, Ossendorp F, and Hennink WE. Near-infrared labeled, ovalbumin loaded polymeric nanoparticles based on a hydrophilic polyester as model vaccine: In vivo tracking and evaluation of antigen-specific CD8+ T cell immune response. Biomaterials 37, 469-477, 2015.  
  2. Bartneck M, Scheyda KM, Warzecha KT, Rizzo LY, Hittatiya K, Luedde T, Storm G, Trautwein C, Lammers T, Tacke F. Fluorescent cell-traceable dexamethasone-loaded liposomes for the treatment of inflammatory liver diseases. Biomaterials 37, 367-382, 2015.
  3. Shirangi M, Sastre Toraño J, Sellergren B, Hennink WE, Somsen GW, and van Nostrum CF. Methyleneation of peptides by N,N,N,N-tetramethylethylenediamine (TEMED) under conditions used for free radical polymerization: a mechanistic study. Bioconjugate Chemistry 26, 90-100, 2015.
  4. Louage B, Zhang Q, Vanparijs N, Voorhaar L, Vande Casteele S, Shi Y, Hennink WE, Van Bocxlaer J, Hoogenboom R, and De Geest BG. Degradable ketal-based block copolymer nanoparticles for anti-cancer drug delivery: a systematic evaluation. Biomacromolecules16, 336-350, 2015.
  5. Novo L, Takeda KM, Petteta T, Dakwar GR, van den Dikkenberg JB, Remaut K, Braeckmans K, van Nostrum CF, Mastrobattista E, and Hennink WE. Targeted decationized polyplexes for siRNA delivery. Molecular Pharmaceutics 12, 150-161, 2015.
  6. Corvo ML, Marinho HS, Marcelino P, Lopes RM, Vale CA, Marques CR, Martins LC, Laverman P, Storm G, and Martins MB. Superoxide dismutase enzymosomes: carrier capacity optimization, in vivo behaviour and therapeutic activity. Pharmaceutical Research 32, 91-102, 2015.
  7. Lammers T, Koczera P, Fokong S, Gremse F, Ehling J, Vogt M, Pich A, Storm G, van Zandvoort M, and Kiessling F. Theranastic USPIO-loaded microbubbles for mediating and monitoring blood-brain permeation. Advanced Functional Materials 25, 36-43, 2015.
  8. Kijanka G, Sauerborn M, Boon L, Schellekens H, and Brinks V. Development of ADA Against Recombinant Human Interferon Beta in Immune Tolerant Mice Requires Rapid Recruitment of CD4+ T Cells, Induces Formation of Germinal Centers but Lacks Susceptibility for (Most) Adjuvants. Journal of Pharmaceutical Sciences 104, 396-406, 2015.
  9. Oude Blenke E, Klaasse G, Merten H, Plcuckthun A, Mastrobattista E, and Martin NI. Liposome functionalization with copper-free ‘click chemistry’. Journal of Controlled Release 202, 14-20, 2015.
  10. Shi Y, Cardoso RM, van Nostrum CF and Hennink WE. Anthracene functionalized thermosensitive and UV-Crosslinkable polymeric micelles. Polymer Chemistry 6, 2048-2053, 2015.
  11. Oerlemans C, Seevinck PR, Smits ML, Hennink WE, Bakker CJ, van den Bosch MA, and Nijsen JF. Holmium-lipiodol-alginate microspheres for fluoroscopy-guided embolotherapy and multimodality imaging. International Journal of Pharmaceutics 482, 47-53, 2015.
  12. Kazazi-Hyseni F, Zandstra J, Popa ER, Goldschmeding R, Lathuile AA, Veldhuis GJ, Van Nostrum CF, Hennink WE, and Kok RJ. Biocompatibility of poly(d,l-lactic-co-hydroxymethyl glycolic acid) microspheres after subcutaneous and subcapsular renal injection. International Journal of Pharmaceutics 482, 99-109, 2015.
  13. Ramazani F, Chen W, Van Nostrum CF, Storm G, Kiessling F, Lammers T, Hennink WE, and Kok RJ. Formulation and characterization of microspheres loaded with imatinib for sustained delivery. International Journal of Pharmaceutics 482, 123-130, 2015.
  14. Lammertink B, Deckers R, Storm G, Moonen C, and Bos C. Duration of ultrasound-mediated enhanced plasma membrane permeability. International Journal of Pharmaceutics 482, 92-98, 2015.
  15. Sasaki N, Bos C, Escoffre JM, Storm G, and Moonen C. Development of a tumor tissue mimicking model with endothelial cell layer and collagen gel for evaluating drug penetration. International Journal of Pharmaceutics 482, 118-123, 2015.
  16. Petit A, Redout EM, van de Lest CH, de Grauw JC, Müller B, Meyboom R, van Midwoud P, Vermonden  T, Hennink WE, and van Weeren PR. Sustained intra-articular release of celecoxib from in situ forming gels made of acetyl-capped PCLA-PEG-PCLA triblock copolymers in horses. Biomaterials 53, 426-436, 2015.
  17. Hu Q, Rijcken CJ, Banasal R, Hennink WE, Storm G, and Prakash J. Complete regression of breast tumour with a single dose of docetaxel-entrapped core-cross-linked polymeric micelles. Biomaterials 53, 370-378, 2015.
  18. Falke LL, van Vuuren SH, Kazazi-Hyseni F, Ramazani F, Nguyen TQ, Veldhuis GJ, Maarseveen EM, Zandstra J, Zuidema J, Duque LF, Steendam R, Popa ER, Kok RJ, Goldschmeding R. Local therapeutic efficacy with reduced systemic side effects by rapamycin-loaded subcapsular microspheres. Biomaterials 42, 151-160, 2015.
  19. Martens TF, Remaut K, Deschout H, Engbersen JF, Hennink WE, van Steenbergen MJ, Demeester J, De Smedt SC, and Braeckmans K. Coating nanocarriers with hyaluronic acid facilitates intravitreal drug delivery for retinal gene therapy. Journal of Controlled Release 202, 83-92, 2015.
  20. Rahimian S, Fransen MF, Kleinovink JW, Christensen JR, Amidi M, Hennink WE, and Ossendorp F. Polymeric nanoparticles for co-delivery of synthetic long peptide antigen and poly IC as therapeutic cancer vaccine formulation. Journal of Controlled Release 203, 16-22, 2015.
  21. Fehres CM, Kalay H, Bruijns SCM, Musaafir SAM, Ambrosini M, van Bloois L, van Vliet SJ, Storm G, Garcia-Vallejo JJ, and van Kooyk Y. Cross-presentation through langerin and DC-SIGN targeting requires different formulation of glycan-modified antigens. Journal of Controlled Release 203, 67-76, 2015.
  22. Maas SL, de Vrij J, van der Vlist EJ, Geragousian B, van Bloois L, Mastrobattista E, Schiffelers RM, Wauben MH, Broekman ML, Nolte-'t Hoen EN. Possibilities and limitations of current technologies for quantification of biological extracellular vesicles and synthetic mimics. Journal of Controlled Release 200, 87-96, 2015.
  23. Schellekens H, and Moors E. Biosimilars or semi-similars? Nature Biotechnology  33, 19-20, 2015.
  24. Kroon J, Buijs JT, van der Horst G, Cheung H, van der Mark M, van Bloois L, Rizzo LY, Lammers T, Pelger RC, Storm G, van der Pluijm G, and Metselaar JM. Liposomal delivery of dexamethasone attenuates prostate cancer bone metastatic tumor growth In vivo. Prostate 75, 815-824, 2015.
  25. Lobatto ME, Calcagno C, Millon A, Senders ML, Fay F, Robson PM, Ramachandran S, Binderup T, Paridaans MP, Sensarn S, Rogalla S, Gordon RE, Cardoso L, Storm G, Metselaar JM, Contag CH, Stroes ES, Fayad ZA, and Mulder WJ. Atherosclerotic plaque targeting mechanism of long-circulating nanoparticles established by multimodal imaging. ACS Nano 9, 1837-1847, 2015.
  26. Talelli M, Barz M, Rijcken CF, Kiessling F, Hennink WE, and Lammers T. Core-crosslinked polymeric micelles: principles, preparation, biomedical applications and clinical translation. Nano Today 10, 93-117, 2015.
  27. Hu Q, van Gaal EVB, Brundel P, Ippel H, Hackeng T, Rijcken CJF, Storm G, Hennink WE, and Prakash J. A novel approach for the intravenous delivery of leuprolide using core cross-linked polymeric micelles. Journal of Controlled Release 205, 98-108, 2015.
  28. Shi Y, van der Meel R, Theek B, Oude Blenke E, Pieters EH, Fens MH, Ehling J, Schiffelers RM, Storm G, van Nostrum CF, Lammers T, Hennink WE. Complete regression of xenograft tumors upon targeted delivery of paclitaxel via Π-Π stacking stabilized polymeric micelles. ACS Nano 9, 3740-3752, 2015.
  29. Falke L, Gholizadeh Soltani S, Goldschmeding R, Kok RJ, and Nguyen T. Diverse origins of the myofibroblast-implications for kidney fibrosis. Nature Reviews Nephrology 11, 233-244, 2015.
  30. Shi Y, Kunjachan S, Wu Z, Gremse F, Moeckel D, van Zandvoort D, Kiessling F, van Nostrum CF, HenninkWE and Lammers T. Double fluorophore-labeling of core-crosslinked polymeric micelles for multimodal in vivo and ex vivo optical imaging. Nanomedicine 10, 1111-1125, 2015.
  31. Van der Geest T, Metselaar JM, Gerrits D, van Lent PL, Storm G, Laverman P, and  Boerman OC. [18]F FDG PET/CT imaging to monitor the therapeutic effect of liposome-encapsulated prednisolone in experimental rheumatoid arthritis. Journal of Controlled Release 209, 20-26, 2015.
  32. Van Meer PJ, Ebbers HC, Kooijman M, Gispen-de Wied CC, Silva-Lima B, Moors EH, and Schellekens H. Contribution of animal studies to evaluate the similarity of biosimilars to reference products. Drug Discovery Today 20, 483-490, 2015.
  33. Rood J, Nawzad H, Kalicharan R, van Steenbergen M, and Vromans H. Drug release from an oromucosal paste for the selective decontamination of the oropharynx (in ICU patients and healthy volunteers). European Journal of Pharmaceutical Sciences 73, 88-92, 2015.
  34. Smits EA, Soetekouw JA, Bakker PF, Baijens BJ, Vromans H. Plasma, blood and liver tissue sample preparation methods for the separate quantification of liposomal-encapsulated prednisolone phosphate and non-encapsulated prednisolone. Journal of Liposome Research 25, 46-57, 2015.
  35. Rahimian S, Fransen MF, Kleinovink JW, Amidi M, Ossendorp F, and Hennink WE. Polymeric microparticles for sustained and local delivery of antiCD40 and antiCTLA-4 in immunotherapy of cancer. Biomaterials 61, 33-40, 2015
  36. Li D, Kordalivand N, Fransen  MF,Ossendorp F, Raemdonck K, Vermonden T, Hennink WE, and van Nostrum CF. Reduction-sensitive dextran nanogels aimed for intracellular delivery of antigens. Advanced Functional Materials 25, 2993-3003, 2015.
  37. Kazazi-Hyseni F, van Vuuren SH, van der Giezen DM, Pieters EH, Ramazani F, Rodriguez S, Veldhuis GJ, Goldschmeding R, van Nostrum CF, Hennink WE, and Kok RJ. Release and pharmacokinetics of near-infrared labeled albumin from monodisperse poly(D,L-lactic-co-hydroxymethyl glycolic acid) microspheres after subcapsular renal injection. Acta Biomaterialia 22, 141-154, 2015.
  38. Rad-Malekshahi M, Visscher KM, Rodrigues JP, de Vries R, Hennink WE, Baldus M, Bonvin AM, Mastrobattista E, and Weingarth M. The supramolecular organization of a peptide-based nanocarrier at high molecular detail. Journal of the American Chemical Society 137, 7775-7784, 2015.
  39. Shi Y, van Nostrum CF, and Hennink WE. Interfacially hydrazine cross-linked thermosensitive polymeric micelles for acid-triggered release of paclitaxel. ACS Biomaterials Science and Engineering 1, 393-404, 2015.
  40. Chen W, Habraken TC, Hennink WE, and Kok RJ. Polymer-free drug-eluting stents: An overview of coating strategies and comparison with polymer-coated drug-eluting stents. Bioconjugate Chemistry 26, 1277-1288, 2015.
  41. Vanprijs N, Maji S, Louage B, Voorhaar L, Laplace D, Zhang Q, Shi Y, Hennink WE, Hoogenboom R, De Geest BG. Polymer-protein conjugation via a ‘grafting to’ approach – a comparative study of protein-reactive RAFT chain transfer agents. Polymer Chemistry 6, 5602-5614, 2015.
  42. Shirangi M, Hennink WE, Somsen GW, van Nostrum CF. Identification and assessment of octreotide acylation in polyester microspheres by LC-MS/MS. Pharmaceutical Research 32, 3044-3054, 2015.
  43. Novo L, Mastrobattista E, van Nostrum CF, Lammers T, Hennink WE. Decationized polyplexes for gene delivery. Expert Opinion on Drug Delivery 12, 507-512, 2015.
  44. Naksuriya O, Shi Y, van Nostrum CF Anuchapreeda S, Hennink WE and Okonogi S.  HPMA-based polymeric micelles for curcumin solubilization and inhibition of cancer cell growth. European Journal of Pharmaceutics and Biopharmaceutics 94, 501-512, 2015.
  45. Ojha T, Rizzo L, Storm G, Kiessling F, and Lammers T. Image-guided drug delivery: preclinical applications and clinical translation.  Expert Opinion on Drug Delivery 12, 1203-1207, 2015.
  46. Geuijen KPHalim LASchellekens HSchasfoort RBWijffels RH, and Eppink MH. Label-free glycoprofiling with multiplex surface plasmon resonance: A tool to quantify sialylation of erythropoietin. Analytical Chemistry 18, 8115-8122, 2015.
  47. Bansal R, Frelin L, Brenndörfer ED, Storm G, Prakash J, and Sällberg M. Hepatitis C virus nonstructural 3/4A protein dampens inflammation and contributes to slow fibrosis progression during chronic fibrosis in vivo. PLoS One 10(6):e0128466, 2015.
  48. Minghetti P, Rocco P, and Schellekens H. The constrained prescription, interchangeability and substitution of biosimilars. Nature Biotechnology 33, 688-689, 2015.
  49. Boere KWM, van den Dikkenberg J, Gao Y, Visser J, Hennink WE, and Vermonden T. Thermogelling and chemoselectively cross-linked hydrogels with controlled mechanical properties and degradation behavior. Biomacromolecules 16, 2840-2851, 2015.
  50. Rahimian S, Fransen MF, Kleinovink JW, Amidi M, Ossendorp F, and Hennink WE. Particulate systems based on poly(lactic-co-glycolic)acid (pLGA) for immunotherapy of cancer. Current Pharmaceutical Design 21, 2015, 4201-4216.
  51. Kunjachan S, Ehling J, Storm G, Kiessling F, and Lammers T. Noninvasive imaging of nanomedicines and nanotheranostics: principles, progress, and prospects. Chemical Reviews 115, 10907-10937, 2015.
  52. Boks MA, Ambrosini M, Bruijns SC, Kalay H, van Bloois L, Storm G, Garcia-Vallejo JT, and van Kooyk. MPLA incorporation into DC-targeting glycoliposomes favours anti-tumour T cell responses Journal of Controlled Release 216, 37-46, 2015.
  53. Fehres CM, van Beelen AJ, Bruijns SC, Ambrosini M, Kalay H, van Bloois L, Unger WW, Garcia-Vallejo JJ, Storm G, de Gruijl TD, van Kooyk Y. In-situ delivery of antigen to DC-SIGN+CD14+ dermal dendritic cells results in enhanced CD8+ T cell responses. Journal of Investigative Dermatology 135, 2228-2236, 2015.
  54. Lobatto ME, Calcagno C, Otten MJ, Millon A, Ramachandran S, Paridaans MP, van der Valk FM,Storm G, Stroes ES, Fayad ZA, Mulder WJ, and Metselaar JM. Pharmaceutical development and preclinical evaluation of a GMP-grade anti-inflammatory nanotherapy. Nanomedicine 11, 1133-1140, 2015.
  55. Ramazani F, Hiemstra C, Steendam R, Kazazi-Hyseni F, Van Nostrum CF, Storm G, Kiessling F, Lammers T, Hennink WE, Kok RJ. Sunitinib microspheres based on [PDLLA-PEG-PDLLA]-b-PLLA multi-block copolymers for ocular drug delivery. European Journal of Pharmaceutics and Biopharmaceutics 95, 368-375, 2015.
  56. Van den Biggelaar M, Madsen JJ, Faber JH, Zuurveld MG, van der Zwaan C, Olsen OH, Stennicke HR, Mertens K, an Meijer AB. Factor VIII interacts with the endocytic receptor low-density lipoprotein receptor-related protein 1 via an extended surface comprising "hot-spot" lysine residues. Journal of Biological Chemistry 290, 16463-16476, 2015.
  57. Bloem E, Ebberink EH, van den Biggelaar M, van der Zwaan C, Mertens K, Meijer AB. A novel chemical footprinting approach identifies critical lysine residues involved in the binding of receptor-associated protein to cluster II of LDL receptor-related protein. Biochemical Journal 468, 65-72, 2015.
  58. Visweswaran GR, Gholizadeh S, Ruiters MH, Molema G, Kok RJ, Kamps JA.Targeting rapamycin to podocytes using a vascular cell adhesion molecule-1 (VCAM-1)-harnessed SAINT-based lipid carrier system. PLoS One, e0138870, 2015.
  59. Van Elk, Lorenzato C, Ozbakir B, Oerlemans C, Storm G, Nijsen F, Deckers R, Vermonden T, and Hennink WE. European Polymer Journal 72, 620-631, 2015.
  60. Vermonden T, and Klumperman B. The past, present and future of hydrogels. European Polymer Journal 72, 341-343, 2015.
  61. Dubbini A, Censi R, Butini ME, Sabbieti MG, Agas D, Tina Vermonden, and Piera Di Martino. Injectable hyaluronic acid/PEG-p(HPMAm-lac)-based hydrogels dually cross-linked by thermal gelling and Michael addition. European Polymer Journal 72, 423-437, 2015.
  62. Van Elk M, Ozbakir B, Barten-Rijbroek AD, Storm G, Nijsen F, Hennink WE, Vermonden T and Deckers R. Alginate microspheres containing temperature sensitive liposomes (TSL) for MR-guided embolization and triggered release of doxorubicin. PLoS ONE 10(11), e0141626, 2015.
  63. Dolman ME, Poon E, Ebus ME, den Hartog IJ, van Noesel CJ, Jamin Y, Hallsworth A, Robinson SP, Petrie K, Sparidans RW, Kok RJ, Versteeg R, Caron HN, Chesler L, and Molenaar JJ. Cyclin-dependent kinase inhibitor AT7519 as a potential drug for MYCN-dependent neuroblastoma. Clinical Cancer Research 21, 5100-5109, 2015.
  64. Van der Geest T, Laverman P, Gerrits D, Franssen GM, Metselaar JM, Storm G, and Boerman OC. Comparison of three remote radiolabelling methods for long-circulating liposomes. Journal of Controlled Release 220, 239-244, 2015.
  65. Underwood C, Pollitt CC, Metselaar JM, Laverman P, van Bloois L, van den Hoven JM, Storm G,  and van Eps AW. Distribution of technetium-99m PEG-liposomes during oligofructose-induced laminitis development in horses. Veterinary Journal 206, 218-225, 2015.
  66. Schellekens H, Lietzan E, Faccin F, and Venema J. Biosimilar monoclonal antibodies: the scientific basis for extrapolation. Expert Opinion Biological Therapy 15, 1633-1646, 2015.
  67. Boere KWM, Blokzijl MM, Visser K, Linssen EA Malda J, Hennink WE and Vermonden R. Biofabrication of reinforced 3D-scaffolds using two-component hydrogels. Journal of Materials Chemistry B. 3, 9067-7078, 2015.
  68. Kroon J, Puhr M, Buijs JT, van der Horst G, Hemmer DM, Marijt KA, Hwang MS, Masood M, Grimm S, Storm G, Metselaar JM, Meijer OC, Culig Z, van der Pluijm G. Glucocorticoid receptor antagonism reverts docetaxel resistance in human prostate cancer. Endocr Relat Cancer. 2016; 23(1): 35-45.
  69. Van der Valk FM, van Wijk DF, Lobatto ME, Verberne HJ, Storm G, Willems MC, Legemate DA, Nederveen AJ, Calcagno C, Mani V, Ramachandran S, Paridaans MP, Otten MJ, Dallinga-Thie GM, Fayad ZA, Nieuwdorp M, Schulte DM, Metselaar JM, Mulder WJ, Stroes ES. Prednisolone-containing liposomes accumulate in human atherosclerotic macrophages upon intravenous administration. Nanomedicine. 2015; 11(5): 1039-1046.
  70. Bansal R, Van Baarlen J, Storm G, Prakash J. The interplay of the Notch signaling in hepatic stellate cells and macrophages determines the fate of liver fibrogenesis. Scientific Reports 2015; 5, 18272; doi: 10.1038/srep18272 (2015). (IF2014: 5.58)
  71. Boks MA, Bruijns SC, Ambrosini M, Kalay H, van Bloois L, Storm G, Gruijl Td, van Kooyk Y. In situ delivery of tumor antigen- and adjuvant-loaded liposomes boosts antigen-apecific T-Cell responses by human dermal dendritic cells. J Invest Dermatol. 2015 Nov;135(11):2697-704
  72. Negussie AH, Dreher MR, Johnson CG, Tang Y, Lewis AL, Storm G, Sharma KV, Wood BJ. Synthesis and characterization of image-able polyvinyl alcohol microspheres for image-guided chemoembolization. J Mater Sci Mater Med. 2015 Jun;26(6):198.
  73. Duinhouwer, L. E., Tüysüz, N., Rombouts, E. W., Ter Borg, M. N., Mastrobattista, E., Spanholtz, J., ... & Braakman, E. (2015). Wnt3a Protein Reduces Growth Factor-Driven Expansion of Human Hematopoietic Stem and Progenitor Cells in Serum-Free Cultures. PloS one10(3).
  74. Elevated urinary CTGF in diabetic nephropathy is caused by local production and tubular dysfunction. Gerritsen KG, Leeuwis JW, Koeners MP, Bakker SJ, van Oeveren W, Aten J, Tarnow L, Rossing P, Wetzels JF, Joles JA, Kok RJ, Goldschmeding R, Nguyen TQ. Journal of Diabetes Research 2015, 2015:539787.