Shared Space, Shared Instruments, Shared Knowledge, Shared Science

a small painting of two proteins interacting with terminal beta sheets on a blue background.

The Protein Research Centre is an expertise platform for protein research at Utrecht University, providing a shared lab space for protein production, purification and characterization. Access is available for state-of-the-art equipment for all life science researchers.

Instruments

Our instruments are divided into techniques used for Biophysical analysis of proteins and protein-interactions, and techniques to purify the proteins. 

For more information on the Biophysical analysis techniques you can look under the "Techniques" tab. For selected publications where our techniques have been used, you can look at the bottom of this page below contact information. 

Biophysical Analysis

Protein Purification

Contact

The Protein Research Centre is located at the Hugo R. Kruyt Building, on the east wing at the 8th floor. 

Address:
Padualaan 8,
3584 CH Utrecht

For questions, training and booking, please contact Renée Koopman:
Email: e.r.koopman@uu.nl
Phone nr.: 030 253 6454

Selected Publications

Fibril fragmentation generates diversity in seed population. Júlia Aragonès Pedrola, Marija Todorovska, Shalini Singh, Assaf Friedler, Stefan G. D. Rüdiger, bioRxiv 2024.11.12.623277; doi: https://doi.org/10.1101/2024.11.12.623277

FibrilPaint to determine the length of Tau amyloids in fluids. Júlia Aragonès Pedrola, Françoise A. Dekker, Tommaso Garfagnini, Guy Mayer, Margreet B. Koopman, Menno Bergmeijer, Friedrich Förster, Jeroen J. M. Hoozemans, Henrik Jensen, Assaf Friedler, Stefan G. D. Rüdiger, bioRxiv 2023.10.13.562220; doi: https://doi.org/10.1101/2023.10.13.562220

GAPR-1 Interferes with Condensate Formation of Beclin 1 in Saccharomyces cerevisiae. Sirati N, Shen Z, Olrichs NK, Popova B, Verhoek IC, Lagerwaard IM, Braus GH, Kaloyanova DV, Helms J, B.J Mol Biol. 2023 Feb 28;435(4):167935. 167935. Epub 2022 Dec 28. PMID: 36586462. doi: 10.1016/j.jmb.2022.