Antimicrobial usage (AMU) surveillance in the Myanmar poultry sector and associated project activities

Study after determinants for behaviour and behaviour change techniques for a low use of antimicrobials in farm animals. Collaboration with Wageningen University and Research.

Intervention trial with a coachingmodel in veal calf farms with a high antimicrobial use. Collaboration with Wageningen University and Research.

https://www.uu.nl/organisatie/veterinaire-service-en-samenwerking/lopend-onderzoek/kritische-succesfactoren-dierenartsen/ksf3-vleeskalveren

Antimicrobial resistance (AMR) is a major threat for public health and is caused by use of antimicrobials in humans and animals. In Indonesia, high amounts of antimicrobials are used in the poultry sector. As antimicrobials are widely used by farmers without prescription, and they are called to reduce antimicrobial use (AMU), there is a need to know why antimicrobials are used and what alternatives can be offered to prevent production losses and keep animals healthy while reducing AMU. In the NWO-CORNERSTONE project (started April 1st 2019) this will be studied. However, more in-depth knowledge of the infectious diseases (viral and bacterial) that are present on the farms is needed to better understand why specific antimicrobials are used and what alternatives can be offered to prevent these diseases and use antimicrobials responsibly when diseases occur. By using diagnostic tests, this Hestia project investigates the presence of viruses and bacteria on farms included in the CORNERSTONE-study, and when they occur. This knowledge can be used to develop tailored interventions consisting of specific biosecurity (hygiene) measures and vaccination programs. Prevention of these diseases has a huge potential to reduce AMU. The knowledge of this project is not only of value for the participating farmers (n=25), but gives more insight in the bacteria and viruses that typically threaten animal health on Indonesian poultry farms. It can also be used to support other poultry farmers in the poultry-dense areas in Indonesia and countries in the region with comparable poultry production systems, in their sustainable farming.

https://www.nwo.nl/projecten/vidw115419017-0

• prof. dr. J.A. (Jaap) Wagenaar

Antimicrobial resistance (AMR) is a major threat for animal and public health and recognized by Heads of State in the General Assembly of the United Nations as a major issue on global scale. To contain AMR, antimicrobial usage (AMU) should be reduced as this is considered to be the main driver of selection for resistant bacteria. Furthermore, the veterinary use of (highly prioritized) critically important antimicrobials for human medicine should be reduced as much as possible and replaced by less important antimicrobials for human medicine. Preliminary data collected by consortium partners, showed considerable overuse of antimicrobials in the Indonesian poultry production. Scientific research is needed to support an evidence-based transition towards a sustainable poultry production chain with responsible use of antimicrobials. The research questions are i) why, what and how much antimicrobials are used in broiler production in Indonesia, ii) what alternatives for AMU are available iii) is it possible to reduce AMU by introducing tailor made on-farm intervention strategies. The parameters to be measured are reduction in AMU and the change in AMR levels on farms. One of the results of this project will be the development of a ‘best practice’ document to be used (inter)nationally by stakeholders and scientific publications to share the results with the scientific community. The consortium consists of research organisations, a commercial partner and 4 supporting organisations with strong links with the broiler sector in Indonesia. Two stakeholder meetings will be part of this project to ensure close involvement in the development of the intervention and in the end phase to communicate results and best practices to end-users. Several elements of capacity building are one of the pillars of the project. This project contributes to a safe and sustainable poultry food chain in Indonesia and reduces the risks of resistant bacteria for humans.

https://www.nwo.nl/projecten/w-07501827-0

• prof. dr. J.A. (Jaap) Wagenaar

Research project after the selection of ESBLs in dairy cows after intramammary application of cephapirin and cefalonium

• dr. A.L. (Aldert) Zomer

Over the last years, the Netherlands has know a succesfull approach to reduce antimicrobial use in farm animals and it is to be expected that a further reduction is possible. To support a responsible reduction in antimicrobial use, a couple of veterinary guidelines have been developed. However, circumstantial evidence indicates that implementation of these guidelines can be improved. In the project VET-ENHANCE, we will study to what extend the veterinary guidelines are being implemented by veterinarians and how the adoption and implementation can be improved. In an intervention trial, we will evaluate whether the implementation of veterinary guidelines can be improved through which we will be able to further reduce antimicrobial use in animals.

https://www.uu.nl/organisatie/faculteit-diergeneeskunde/over-de-faculteit/departement-biomolecular-health-sciences/infectieziekten-en-immunologie/onderzoek/vet-enhance 

• ing. Isaura Wayop MSc
• prof. dr. J.A. (Jaap) Wagenaar

In this project we will identify critical success factors for a low antimicrobial use in pig farming. We will collect a lot of data from a large number of pig farms and relate this to the antimicrobial use at farm level. We will also try to synthesize information from other sources that are believed to influence antimicrobial use in pig farming. With this information, we will try to identify key factors for antimicrobial use and will translate those to specific measures that pig farmers can use to reduce antimicrobial use. The effect of these measures will be measured in terms of antimicrobial use and resistance levels.

https://www.infectionandimmunity.nl/projects/details/reduction-of-antimicrobial-use-on-farms-by-targeting-critical-success-factors-in-farm-management

• prof. dr. J.A. (Jaap) Wagenaar

Research project Critical Success Factors for Antibiotic Prescribing of Farm Animal Veterinarians. Commissioned by the Ministry of Economic Affairs, the Netherlands. Aim of this study is to elucidate key success factors for a restrictive prescription of antimicrobials by farm animal veterinarians.

https://www.uu.nl/organisatie/veterinaire-service-en-samenwerking/lopend-onderzoek/ksf-dierenartsen