We investigate cytoskeletal organization and trafficking processes, which contribute to cell polarization, differentiation, vertebrate development and human disease. 

The primary goal of the lab is to understand how intracellular trafficking underlies neuronal development and synapse function.

Our goal is to obtain a physical understanding of the mechanisms by which cells establish and maintain their precise shape and intracellular organization.

Our goal is to develop novel technologies for the diagnosis, molecular imaging and targeted therapy of cancer.  In our research we make use of single domain antibodies (VHH or nanobodies).

We study the functioning of the brain during development and in adult life focusing on genetic malformations and autoimmune antibodies targeting neuronal proteins.

The strength and number of synapses are adjusted by experience. We study how the changes in excitatory and inhibitory synapses are coordinated to balance the two opposing forces.

Our group aims to understand how axons generate and conduct electrical impulses by investigating the properties and functions of its axonal domains and the myelin sheaths.

To gain insight into cellular functioning, we apply and develop novel visualization approaches such as correlative Light-Electron Microscopy and 3D-Electron Microscopy.