Researchers from the University Medical Centre Utrecht have successfully expanded their in vivo research with New Approach Methodologies (NAMs) with support from the 3Rs Centre Utrecht (3RCU). Parallel studies were established in collaboration with international colleagues, who work with NAMs. Tailored guidance for researchers and other stakeholders has become more official at the 3RCU with the establishment of a support desk on NAMs: Suppo3Rt.
The 2024 Annual Report on Animal Experiments by Utrecht University and the University Medical Center (UMC) Utrecht provides, for the first time, insight into the so-called ‘Invisible animal use’ in biomedical research within both organizations.
At the UMC Utrecht Department of Radiology and Nuclear Medicine, the research group of Dr. Alex Poot is developing radioactive compounds for cancer treatment. These theranostics are tested on tumor cells, organoids, patient-derived tissue, and animal models. Our student assistant Soléne Feyzi explored an innovative, animal-free alternative: the chicken chorioallantoic membrane (CAM) model.