3. The FCS-free Database (fcs-free.org) provides an overview of the range of commercially available FCS-free media for cell-culture. Fetal Calf Serum (FCS, also known as Fetal Bovine Serum, or FBS) is a common supplement of animal cell culture media. However, FCS is harvested, with a high chance of suffering, from bovine foetuses taken from pregnant cows during slaughter. Furthermore, since it is a natural product, the composition of the commercially available FCS varies from batch to batch, which impedes the reproducibility of results. These moral and scientific concerns demonstrate the urgency to switch to an FCS-free medium. The FCS-free Database is used as a platform for researchers to discuss the applicability of each product. Besides a list of commercially available FCS-free media, the website also contains medium compositions obtained from scientific literature. The database is offered by the 3Rs-Centre ULS in collaboration with Animal Free Research UK.
These three information sources do not receive any subsidies and therefore their future rely on donations and gifts. You can help keeping the websites available by donating only a small amount of money for the Interspecies Database, the Humane Endpoints website or the FCS-free Database. We are happy with all donations and thank you very much for your help!