Courses

Medical imaging specific courses

Advanced MR Physics 1

Period (from – till): 12 November 2020 - 4 February 2021

Course coordinator: Dr. ir. Wilbert Bartels.
Lecturers
Dr.ir. Wilbert Bartels, UMC Utrecht/Imaging & Oncology Division, lecturer
Dr. Clemens Bos, UMC Utrecht/Imaging & Oncology Division, lecturer

Course description
This advanced MRI course covers the physical principles of MRI and sequence design issues.
Topics that will be covered are:

  • The classical NMR mode: nucleus in a magnetic field
  • Rotating reference frame & resonance
  • Bloch equations
  • Signal detection concepts
  • Signal acquisition: FID and echo techniques
  • Multi-dimensional Fourier imaging and k-space
  • Fourier image reconstruction
  • Signal, contrast and noise
  • Basic sequence design

For the lectures (morning sessions) attendance is highly recommended; the tutorial sessions in the afternoon are mandatory: students have to prepare and present assignments.

Literature/study material used
Magnetic resonance imaging: Physical principles and sequence design. E.M. Haacke, R.W. Brown, M.R. Thompson, R. Venkatesan. John Wiley & Sons, New York, 1999 and hand-outs provided by the lecturers.
Registration
You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
Students from outside the UU or TU/E partnership can register for this course by sending an email to mix@isi.uu.nl. Please include your name, student number, Master’s programme and the course code.
Mandatory
No.

Optional for students in other GSLS Master’s programme:
Yes.

Prerequisite knowledge:
Basic knowledge of mathematics (differential equations, vector calculus, Fourier analysis, complex functions, electromagnetism (Faraday’s law of induction, static magnetic field calculations, electromagnetic waves)) and MRI at BSc level. Preferably also the study material on MRI provided in the Medical Imaging course Medical Image Formation.

Advanced MR Physics 2

Period (from – till): 12 Febuary 2021 - 16 April 2021

Course coordinator: Dr. J.C.W. Siero
Lecturers
Dr. J.C.W. Siero, UMC Utrecht/Imaging Division, lecturer
Renée Allebrandi, MA (course contact person)
Course description
This advanced MRI course builds on the course Advanced MR Physics 1. It focusses on MR imaging methods and applications. The mathematical and physical framework laid down in AMRP 1 is used to focus on MR imaging methods and applications: fast spin- and gradient-echo imaging, spectroscopy, MR angiography, perfusion, diffusion and susceptibility weighted imaging and quantification, scan acceleration techniques.

For the lectures (morning sessions) attendance is highly recommended; the tutorial sessions in the afternoon are mandatory.
Literature/study material used
-
Registration
You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
Students from outside the UU or TU/E partnership can register for this course by sending an email to mix@isi.uu.nl. Please include your name, student number, Master’s programme and the course code.
Mandatory
No.

Optional for students in other GSLS Master’s programme:
Yes, provided they have passed the course Advanced MR Physics 1.

Prerequisite knowledge:
Advanced MR Physics 1

Capita Selecta in Medical Image Analysis TU/Eindhoven

Period (from – till): 3 February - 17 April 2020
Course coordinator: Renée Allebrandi, MA (course contact person)
Course aims and content:
PLEASE NOTE THAT THIS COURSE IS TAUGHT IN EINDHOVEN
This course covers a number of state-of-the-art techniques and topics in medical image analysis. It is a specialisation course for those with a general understanding of medical image analysis looking to deepen their knowledge. The topics of this year are

  • Deep Learning
  • Image Registration and Validation

You will learn about machine learning, (convolutional) neural networks and how to train them. The second part of the course considers nonlinear image registration and proper methods to set up a validation study. Each part of the course will come with a large group assignment on actual medical data to give you hands-on experience, both in a deep learning approach to a medical image analysis problem and in nonlinear image registration for clinical data.
Literature/study material used
Slide hand-outs, Deep Learning by Goodfellow, Bengio and Courville; other material will be made available
Registration
Please register at TU/e, course code 8DM20, at least 4 weeks before start of the course. Osiris registration will be done retroactively when results from the TU/e are received.
Mandatory
No.

Optional for students in other GSLS Master’s programme:
No.

Capita Selecta in Medical Imaging

Period (from – till): 9 November 2020 - 1 February 2021
Course coordinator: Dr. Alexander Leemans
Faculty
Dr. Alexander Leemans, UMC Utrecht/Imaging & Oncology Division, lecturer
Dr. Hugo Kuijf, UMC Utrecht/Imaging Imaging & Oncology, lecturer
Renée Allebrandi, MA (course registration)
Course description:
This course consists of two independent topics. During the first half of the course , topics on deep learning for medical image analysis will be introduced: :

  • Machine Learning fundamentals
  • Deep Learning
  • Convolutional Neural Network
  • Network Architectures
  • Medical Image Analysis applications

During practical sessions students will improve their understanding of the above topics. Additionally there will be a homework group assignment to be handed in at the end of the course.

The second half of the course covers theory and practice of processing, analysing and visualising diffusion MRI data. Key concepts and practical considerations of data processing and analysis are explained. Topics include

  • Quality assessment
  • Artifact correction
  • Diffusion approaches
  • Fiber tractography
  • Automated analyses
  • Visualisation methods

During computer practical sessions students will learn how to work with real diffusion MRI data.

Literature/study material used:
Deep Learning, by Goodfellow, Bengio, Courville, https://www.deeplearningbook.org/
hand-outs provided by lecturers
suggested reading material

Details: https://mix.isi.uu.nl/courses/capita-selecta-medical-imaging-uu/

RegistrationYou can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
Students from outside the UU or TU/E partnership can register for this course by sending an email to mix@isi.uu.nl. Please include your name, student number, Master’s programme and the course code.
Mandatory
No.

Optional for students in other GSLS Master’s programme:
Yes.

Image Processing

Period (from – till): 8 September 2020 - 29 January 2021
Course coordinator: Dr. Kenneth Gilhuijs
Faculty
Dr. Alexander Leemans, UMC Utrecht/Imaging Division, lecturer
Dr. Kenneth Gilhuijs, UMC Utrecht/Imaging Division, lecturer
Renée Allebrandi, MA (course contact person)

Course content
This course covers the full roadmap from basic to more advanced techniques that are commonly used in medical image processing. You will learn how to analyse concrete medical questions that arise from medical images, and that can be solved by mathematical analysis of CT, MRI and X-ray. We will take you from theory to design of computer-aided diagnosis systems and Radiomics systems. Examples of such systems are those that automatically detect tumors in CT and MRI scans, that automatically detect micro-aneurysms in retinal images, or that estimate the prognosis of breast-cancer patients based on imaging features that cannot be picked up by the human eye. Topics include segmentation (dynamic programming, active contours, level sets), image registration, mathematical morphology, texture analysis, pattern recognition (feature spaces, classifiers; support-vector machines and random forests). During the lectures we will provide small practical assignments using a voting system. A computer practicum will be provided to get hands-on experience with the different techniques. In addition, individual assignments are provided consisting of actual problems that were encountered in medical images.

Literature/study material used:
Book: Image Processing, Analysis, and Machine vision (Sonka, Hlavac, Boyle), as well as handout materials.

Details: https://mix.isi.uu.nl/courses/image-processing/

Registration
Medical Imaging students are registered automatically for this course upon entering the Masterprogramme.
Other UU and TU/e partnership students can register register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
Students from outside the UU or TU/E partnership can register for this course by sending an email to mix@isi.uu.nl. Please include your name, student number, Master’s programme and the course code.
Mandatory :
Yes, for MIMG students.

Optional for students in other GSLS Master’s programme:
Yes.

Prerequisite knowledge:
A BSc in

  • (applied) physics
  • (applied) mathematics
  • computer science
  • biomedical engineering
  • science major of University College Utrecht
  • electrical engineering
  • or similar degree

Medical Image Formation

Period (from – till): 7 September 2020 - 6 November 2020

Course coordinator: Dr.ir. Wilbert Bartels
Lecturers
Dr.ir. Wilbert Bartels, UMC Utrecht/Imaging Division, lecturer
Dr. Arnold Schilham, UMC Utrecht/Imaging Division, lecturer
Dr.ir. Roel Deckers, UMC Utrecht/Imaging Division, lecturer
Dr.ir. Bastiaan van Nierop, UMC Utrecht/Imaging Division, lecturer
Renée Allebrandi, MA (course contact person)
Course description
In this course the physics behind the most important medical imaging modalities will be treated. After an introductory lecture, x-ray imaging (radiography, fluoroscopy, digital subtraction angiography, computed tomography), ultrasound, nuclear imaging techniques (SPECT & PET) and magnetic resonance imaging will be discussed. The increasing importance of medical imaging for guiding surgery and minimally invasive radiological interventions will be emphasized. During the course, representative problems will be handed out and discussed.

Literature/study material used:
“The essential Physics of medical Imaging”, authors: Bushberg, Boone, Leidholdt and seibert; 3rd revised edition ISBN-10: 1451118104
“Basic Principles of MR Imaging”; published by Philips Nederland (to be purchased from the Education Coordinator)

Registration:
Medical Imaging students are registered automatically for this course upon entering the Masterprogramme.
Other UU and TU/e partnership students can register register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
Students from outside the UU or TU/E partnership can register for this course by sending an email to mix@isi.uu.nl. Please include your name, student number, Master’s programme and the course code.
Mandatory for students in Master’s programme:
Yes, for MIMG students.
Optional for students in other GSLS Master’s programme:
Yes.

Prerequisite knowledge:
A BSc in

  • (applied) physics
  • (applied) mathematics
  • computer science
  • biomedical engineering
  • science major of University College Utrecht
  • electrical engineering
  • or similar degree

Programming for Medical Imaging

Period (from – till): 7 September - 6 November 2020
Course coordinator: Dr. Hugo Kuijf
Faculty
Dr. Hugo Kuijf, UMC Utrecht/Imaging Division, lecturer
Renée Allebrandi, MA (course contact person)
Course description
In the area of medical imaging, it is necessary to create computer programs to process and analyse image data. This course deals with both the theoretical knowledge and practical skills of working with (large) image datasets.

Students will learn how to write source code and create a computer program to process medical images efficiently. This includes debugging and problem solving.

Course includes algorithms and data structures used in medical image analysis. Modern programming techniques are used, paying attention to efficient computer instructions and memory usage.

Examination:

  • Written exam: 60%
  • Two computer assignments: 40%

The weights indicated above are applied to calculate the final mark. To pass the course the grade for each component must be a 5.0 or higher and the final mark must be an unrounded 5.5 or higher
Literature/study material usedMANDATORY, book will be actively used during the course: Programming Principles and Practice Using C++”, Bjarne Stroustrup, ISBN: 9780321992789 MANDATORY will be used throughout the entire course

Microsoft Visual Studio (free community edition)

ITK Software Guide (via: https://itk.org/ITK/resources/software.html)

Details: https://mix.isi.uu.nl/courses/programming/
Registration
Medical Imaging students are registered automatically for this course upon entering the Masterprogramme.
Other UU and TU/e partnership students can register register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
Students from outside the UU or TU/E partnership can register for this course by sending an email to mix@isi.uu.nl. Please include your name, student number, Master’s programme and the course code.
Mandatory
Yes, for MIMG students.

Optional for students in other GSLS Master’s programme:
Yes.

Prerequisite knowledge:
Basic computer skills

Radiation Physics TU/Eindhoven

Period (from – till): 7 September 2020 - 6 November 2020
Course coordinator:Renée Allebrandi, MA (course contact person)

Course description:
PLEASE NOTE THAT THIS COURSE IS TAUGHT IN EINDHOVEN
In this course the basic notions from atom and nuclear physics are treated. From atomic physics we will discuss: waves and particles, atom models of Rutherford and Bohr, the Schrödinger equation, quantum numbers, x-rays and x-ray tubes. From nuclear physics we will discuss: structure and elementary properties of the nucleus, chart of nuclides, binding energies, atom masse, Q-values, radioactivity with alpha beta and gamma decay.
Literature/study material used:Material for study and exercises are available during lectures; Modern physics by Kenneth Krane, 3rd edition (recommended)
Registration:
Please register at TU/e, course code 8CM10, at least 2 weeks before start of the course. Osiris registration will be done retroactively when results from the TU/e are received.
Mandatory:
No

Optional for students in other GSLS Master’s programme:
No.

Radiotherapy Physics

Period (from – till): 10 February - 14 April 2021
Course coordinator: Dr. B. van Asselen
Faculty
Dr C.P.J. Raaijmakers, UMC Utrecht/Imaging Division, lecturer
Dr B. van Asselen, UMC Utrecht/Imaging Division, lecturer
Dr. M.A. Moerland, UMC Utrecht/Imaging Division, lecturer
Dr.Ir. J.W.H. Wolthaus, UMC Utrecht/Imaging Division, lecturer
Dr. J.C.J. de Boer, UMC Utrecht/Imaging Division, lecturer
Dr. E. Seravalli, UMC Utrecht/Imaging Division, lecturer
Dr. S.L. Hackett, UMC Utrecht/Imaging Division, lecturer
Prof.dr. B.W. Raaymakers, UMC Utrecht/Imaging Division, lecturer
Renée Allebrandi, MA (course registration)

Course descriptionThis course covers practical and theoretical aspects on medical physics in the field of radiotherapy.

First the basic radiation physics will be discussed: e.g.
production of radiation, radioactive decay, characteristics of ionizing radiation, interaction with matter and measurement of absorbed dose.

The next part covers the essentials of dose calculation using various algorithms and dose optimization such as Intensity modulated therapy (IMRT) and volumetric arc therapy (VMAT).

Third topic is image guided radiotherapy (IGRT): e.g. inter- and intrafraction motion, position verification devices (electronic portal imaging device, cone-beam CT and MRI), real time imaging and various methods to deal with motion.

Finally topics in the field of MRI guided treatment will be discussed: e.g. dose delivery in magnetic fields, MRI linac design, workflow and plan adaptation.

Examination:

  • Written exam: 80%; attendance to the practical work is obligatory to qualify for examination
  • Oral presentation and discussion: 20%

The weights indicated above are applied to calculate the final mark. To pass the course the grade for each component must be a 5.0 or higher and the final mark must be an unrounded 5.5 or higher. (Anglo-Saxon grade mark D)

Literature/study material used:

  • Khan’s the physics of radiation therapy, Khan, Faiz M, ISBN 9781451182453. (an electronic version of the book is available at the UU library)
  • Hand-outs.
  • Articles on specific topics

Details: https://mix.isi.uu.nl/courses/radiotherapy-physics/
Registration
You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
Mandatory
No

Optional for students in other GSLS Master’s programme:
No.

RF in MRI TU/Eindhoven

Period (from – till): 3 February 2020 - 17 April 2020
Course coordinator:Renée Allebrandi, MA (course contact person)

Course description:
PLEASE NOTE THAT THIS COURSE IS TAUGHT IN EINDHOVEN
The course will cover all aspects of RF in MRI. The course can be divided in four parts:
To generate RF fields with a RF coil or antenna, the coil or antenna needs to be driven with high power (~kw) RF signals. In the receive phase of the MRI sequence, the spins in the tissue will emit signals that will be detected by the RF coil. The coil will transform these signals into electrical RF signals and sent them to the ADC. The course will give an in-depth treatment of the generation and transportation of these signals. For this purpose, the following concepts will be covered: impedance calculations, RF amplifier classes, transmission lines, Smith Chart, scatter matrices, transmit-receive switches. (2 lectures)
The second part focuses at the coil or antenna. The most-often used types will be covered (loop coil, birdcage coil, dipole antenna and arrays). (1 lecture)
The third part will focus at the fields that are generated by the coil or antenna. The B1 field consists of B1+ en B1-, one only useful for the transmit phase, the other only useful for the receive phase of the MRI sequence. In addition, every coil or antenna also generates (or is sensitive for) electrical fields. These are responsible for energy deposition (SAR) and, in receive, noise. (2 lectures)
The third and last part will cover how relevant metrics of MRI performance can be calculated from (for example simulated) field distributions of RF antenna arrays, such as SNR, noise correlation, optimal reconstructions and g-factor distributions. (2 lectures)
Literature/study material used:Lecture slides and exercises
Registration:
Please register at TU/e, course code 8DM30, at least 4 weeks before start of the course. Osiris registration will be done retroactively when results from the TU/e are received.
Mandatory:
No.

Optional for students in other GSLS Master’s programme:
No.

Team Challenge

Period (from – till): 7 September 2020 – 16 April 2021
Course coordinator: Dr. Hugo Kuijf
Faculty
Dr. Hugo Kuijf, UMC Utrecht/Imaging Division, lecturer
Renée Allebrandi, MA (course contact person)

Course description
This course, which runs over three periods of the academic year, will pose a challenging medical imaging problem that will be addressed by teams composed of students from Utrecht and Eindhoven. Over the course period, teams will first perform a literature study, and subsequently work on a strategy for solving the problem at hand, using their knowledge in image acquisition physics and image analysis. At the end of the course, all teams will present their work.

For communication during the course we will use a slack workplace.
Literature/study material usednone

Registration
Medical Imaging students are registered automatically for this course upon entering the Masterprogramme.
​Mandatory
Yes, for MIMG students.

Optional for students in other GSLS Master’s programme:
No.

Ultrasound in (Bio)medical Engineering TU/Eindhoven

Period (from – till): 11 November 2019 - 31 January 2020
Course coordinator: Renée Allebrandi, MA (course contact person)
Course aims and content:
PLEASE NOTE THAT THIS COURSE IS TAUGHT IN EINDHOVEN
The physics of acoustics (waves and wave propagation) are the foundation of this imaging course. Starting point is the wave equation, after which several models for wave propagation in elastic and visco-elastic tissue and fluids will be treated. Solution to these equations will be derived for point sources and extended to arbitrary apertures. The physics of attenuation (= damping) and its consequences will be discussed. Next, the physics behind US pressure field formation, including reflection, diffraction, and scattering, will be discussed and it will be shown how this forms the basis of in vivo imaging. A number of techniques to improve image formation will be discussed, including array technology, focusing, advanced beam forming, 3-D ultrasound and plane wave imaging techniques. The concept of speckle, speckle statistics and its relation to tissue morphology will be discussed, including techniques for speckle reduction and image enhancement.
Next, a clear overview of medical applications of ultrasound will be given, including all pro’s and con’s and image artefacts. The basic principles of Doppler and the corresponding signal analysis are shown for the commonly used modes (continuous wave, pulsed wave, color flow & power Doppler). Next, relative new techniques will be introduced, such as speckle tracking, strain imaging and (shear wave) elastography. The physics of piezoelectric materials are treated shortly, after which the design of US transducers is discussed. Photoacoustics will be introduced, from photoacoustic effect to medical imaging applications.
Finally, in a number of guest lectures, two more advanced topics will be discussed that are based on non-linear wave propagation: harmonic imaging and contrast agents and contrast-enhanced ultrasound imaging.
Literature/study material used
-
Registration
Please register at TU/e, course code 8VM60, at least 4 weeks before start of the course. Osiris registration will be done retroactively when results from the TU/e are received.
Mandatory
No.

Optional for students in other GSLS Master’s programme:
No.

General elective courses

Academic Writing (online course)

Period (from – till): This online course will be given four times a year, in each period.

Faculty
Course coordinator: Frans (F.W.) van Dam, Lecturer science communication, Faculty of Science (F.W.vanDam@uu.nl)
Lecturers: Mark (M.J.W.) Bos, Lecturer science communication, Faculty of Science (m.j.w.bos@uu.nl) and Frans (F.W.) van Dam

Course description
This mini-course will focus on the demands of ‘academic’ writing in English, and will include topics such as writing strategies, writing plans, revision, writing good paragraphs and structure. It is particularly helpful for students embarking on a research thesis, an internship report or an article.

Registration
This course is (in first instance) open to all second year Master’s students of the Graduate School of Life Sciences. It is important that, during the course, you are writing your internship report, Master's thesis or article.

You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide and placement of students is done by lottery in case of capacity limitations.
The maximum number of participants is 20, the minimum 10.

Course dates
Each course starts in the second week of the period. In 4 online sessions during the course students and the lecturer will meet via MS Teams (45’ sessions). Here you can find the list with all the exact dates per period for the online meetings during the whole year. All online meetings are scheduled between 9:00-12:00h.Between
9:00-12:00hP1
7 Sept 2020 – 30 Oct 2020P2
16 Nov 2020 – 29 Jan 2021P3
15 Feb 2021 – 16 Apr 2021P4
03 May 2021 – 25 Jun 2021Meeting 115 Sept 202024 Nov 202023 Feb 202111 May 2021Meeting 229 Sept 202008 Dec 202009 Mar 202125 May 2021Meeting 313 Oct 202022 Dec 202023 Mar 202108 Jun 2021Meeting 427 Oct 202019 Jan 202106 Apr 202122 Jun 2021

Literature/study material used
All materials and exercises are available through the online Lifelong Learning Platform. Participating students will be enrolled in advance of the course.

Mandatory for students in own Master’s programme:
N.A.

Optional for students in other GSLS Master’s programme:
Yes.

Testimonials
"This short course is very useful and instructive"
"The teacher is very enthusiastic"
"You work on your own report"
"Useful advise about the writing process and common pitfalls"
"Eye-opener"

Basics of Biostatistics

Period (from – till): 09 November 2020 – 22 January 2021

Schedule:
Introduction and discussion statistical theory: week 46 till week 51 2020 (online)
Christmas holiday: week 52 and 53 2020, week 1 2021
Case study (group assignment): week 2 2021 (online)
Exam (individual): week 3 2021 (UMC Utrecht)
Re-exam (individual): week 6 2021 (UMC Utrecht)

Faculty
Paul Westers, GNK (coordinator and online instructor)
Cas Kruitwagen, GNK (web lecturers)
Rebecca Stellato, GNK (web lecturers)

Course description
Basic of Biostatistics is an online course. The course offers a variety of learning activities such as web lectures, discussions and (group)assignments.

The course (4,5 ECTS, study load 16 hours per week) provides the basics of statistical methodology and supplies a number of statistical techniques important for practical data analysis. Examples from the medical and biological fields will be used in exercises. Datasets will be analyzed on the computer using the statistical package SPSS or optional R.

The first part covers statistical testing for one and two samples, confidence intervals, simple linear regression and correlation, one way analysis of variance, binomial distribution and proportions, analysis of contingency tables and non-parametric statistics. The second part introduces the most important regression models used in biomedical research, that can be used in the study of the relation between a number of explanatory variables on the one hand, and the occurrence of an outcome on the other: multiple regression and logistic regression.

NOTE: It is expected that students have some basic knowledge on descriptive statistics and mathematics, such as measures of location (mean, median) and scale (variance, standard deviation), the normal distribution, standard error of the mean. They will not explicitly be repeated in the course, but will be used implicitly.

Literature/study material used:
During the course all the course material will be online available. Besides this online material you can use also one of the following statistical books:

  • W.W. Daniel, Biostatistics: Basic Concepts and Methodology for the Health Sciences, International student version, 9th Edition. John Wiley & Sons, 2010;
  • P. Armitage, G. Berry and J.N.S. Matthews, Statistical Methods in Medical Research, 4th edition. Wiley-Blackwell, 2001;
  • M.C. Whitlock and D. Schluter. The Analysis of Biological Data. Roberts and Company Publishers, 2009;
  • J.H. Zar, Biostatistical Analysis, 5th Edition. Pearson Education International, 2010.

These reference books remain useful long after you have completed the course. You are not obliged to use any of these books during the course.

Brief manuals of SPSS and R will be available online.

Examination
The examination consists of two parts, namely:

  1. a case study (in subgroups of 2-3 students, 25% of final grade)
  2. a final exam (individual, 75% of final grade) consisting of open and multiple choice questions.

The grades for both parts should be at least 5. To pass for the course the final grade should be at least 5.5. If the final grade is lower than 4 it is not allowed to do the re-exam, except if there is a permission from the exam committee.
Furthermore active (online) attendance is mandatory.

Registration
You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
A maximum of 60 students can be enrolled in the course (divided into groups of max 15 students in order to remain small-scale learning).
Mandatory for students in own Master’s programme:
N.A.

Optional for students in other GSLS Master’s programme:
Yes.
Prerequisite knowledge:
If necessary, participants should refresh their knowledge using a statistics book used in previous courses, or using the statistics e-books.

Although active statistical knowledge is not a prerequisite, we assume some basic knowledge on statistics and mathematics acquired through, for example, courses in biostatistics in the bachelor programme or self study.

The basic knowledge we assume are:

  • The concepts of population and sample;
  • Histogram, boxplot, frequency table, scatterplot, contingency table;
  • Mean, median, mode;
  • Variance, standard deviation, range, interquartile range, standard error of the mean;
  • Probability, probability distributions (especially the normal distribution).

If you want to refresh your basic knowledge, we recommend one of the mentioned books (see study material) or one of the following sources of information:

  • The very advanced online textbook Online Statbook;
  • The e-book and/or exercises of CAST (Computer-Assisted Statistics Textbooks)
  • The e-lectures and/or exercises of the Khan Academy (includes also a self-test)
  • The very nice JBstatistics with short video’s but no exercises (no descriptive statistics)

As soon as possible after the enrollment for the course you will get access to the online learning environment of the course and there will be a test available for testing your basic knowledge on statistics and mathematics. It is then also possible to ask online questions with respect to the basic knowledge to the lecturers.

Better science with less animal experimentation

This course will consist of five modules, all of which focus on a different aspect of research and innovation in animal-free methods. The course will include regulatory and communication aspects. During this course, you will focus on innovations in animal-free methods including advanced in vitro (cell culture) and in silico (computational) approaches. The course will highlight the unique advantages of human-derived cells, such as induced pluripotent stem cells, organoids and multi-organ-on-chip devices. You will discover and discuss core topics related to the transition to a more humane science with the help of ethics, statistics and philosophy experts. You will dive in critical data interpretation in order to enhance your understanding of science. A group of experts will teach you the methodology of systematic reviews of scientific studies.

Bio-inspiration Essentials

The subjects being addressed
This is a course that introduces the field of Bio-Inspiration. We start to elucidate the philosophical and historical roots of the concept of bio-inspiration. We will touch upon movements like: deep ecology and permaculture and illustrious predecessors such as, Leonardo da Vinci, Buckminster fuller, Viktor Schauberger, Jay Harman and Bill Mollison.
Next, we will give an overview of the main bio-inspired approaches, being: biomimicry, bionics, nature inspired design, natural capitalism, biophilia, Circular Economy and CtoC. Moreover, you will learn to see similarities and differences, by to comparing and classifying different bio-inspired approaches.
Finally, we will address Design as a discipline and process. In this way you can start to formulate and explore possibilities for innovation as a product, process or systems innovation.
You learn how to define the function you want to ‘biologize’. By doing so, you will describe the scope and hoped-for-outcome in such a way that a biologist can deliver the information as an important co-creative step in an innovation process.

This is an online course stretching over 10 weeks with a study load of approximately 7 hours per week. The course consists of web lectures as well as articles, group assignments, individual assignments, peer feedback and feedback from teachers. During the course you interact with other participants through assignments and discussions. The course is moderated actively by a professional moderator and teaching staff.

The added value for the participants
For students with a chemical biological or bio-medical background it gives a first introduction into a whole new and promising field that combines economic values and methods (innovation) with nature based approaches.
For entrepreneurs, programme & project managers, policymakers, trade and industry professionals: the course will help you to understand the main concepts within bio-inspiration that allow you initiate and direct bio-inspired innovation-trajectories.

Summary of course content (max 75 words)
This course introduces a new field in Science and Design: Bio-Inspiration you will learn to look at nature as source of knowledge that will help to make our products, processes and systems part of nature, compatible with and supporting a transition to a circular economy instead of designing for the ‘dump’. After an overview of different Biologically Inspired approaches you will learn to define the scope and function of an innovation and write a first design-brief.

Bio-Tech-Med interdisciplinary team training (BITT project)

Period (from – till): 24 Febuary - 17 June 2021 Faculty
S. de Jong, PhD, UMCU, DH&L, Med. Physiology, course coordinator.
Course description

This course gives you the opportunity to think about solutions to a disease-related problem and to obtain skills such as working in an interdisciplinary team with master students from the Graduate School of Life Sciences, Medicine Master ‘SUMMA’, and master students from the Technical University Eindhoven.

The overarching aim is, that - based on a real-life patient-oriented problem (e.g. inflammatory bowel disease) - future doctors, engineers, and biomedical scientists will collaborate to come up with a potential solution.

You will work in small interdisciplinary groups guided by experts in the fields of biomed/-tech. The course consists of three plenary meeting days (January 16th – March 5th – May 14th 2020). In between these plenary meeting days, you will work at a distance to keep things going.

Within this elective course you will learn among others about interdisciplinary collaborative skills, design thinking, brainstorming, pitching potential solutions, entrepreneurship, and patient perspectives.

Literature/study material used:
Primary literature

Registration:
You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
Additionally, you are required to send an e-mail to the course coordinator, specifying the course code, the masterprogramme you participate in and your background (biomedical/medical/technical).

Mandatory for students in own Master’s programme:
No

Optional for students in other GSLS Master’s programme:
Yes, for all GSLS students

Prerequisite knowledge
None.

Other remarks
This 3 EC course can be extended to 5 EC. The extension consists of an individual assignment that focuses on the inclusion of additional disciplines in the proposed solution.
Be aware that in that case you should register for the 5 EC variant of this course with course code BMB539019.

Career Orientation and Professional Skills Training

This course is the English version of the Dutch course "Loopbaanoriëntatie en Professionalisering" (B-MLOOP10).
This English version is in principle focused on international students. This course is offered in periods 2 and 4. The Dutch course is offered in all periods.

Please note:
In periods 2 and 4, both courses will be offered simultaneously. Should the total number of registrations for both courses be insufficient to organise both courses concurrently, then the English course has priority. In that case, students of the Dutch course will be asked to participate in the English course. The course dates will remain the same.

Period (from – till): 13 November 2020 - 15 January 2021 in Period 2 and again 10 May 2021 - 28 June 2021 in Period 4 (course is given twice)
Faculty
H.A. de Graaf Beta Biology 50%
M. Otter Faculteit Geneeskunde Career Officer 50%

Course description
The student analyses herself/himself and the work environment. Also to reach his/her goals the student prepares an action plan. Next to this an amount of management skills are trained, i.e. project management, problem solving, personal effectiveness. The class meetings are scheduled on 7 days (9.00-17.00 hrs). The course is finalised with a personal report. Students will be graded.

Literature/study material used
Handouts

Registration

You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
This course is taught twice, in Period 2 and 4.

Mandatory for students in Master’s programme
N.A.

Optional for students in other GSLS Master’s programme
Yes.

Prerequisite knowledge
N.A.

Teaching Schedule
Edition 1 with 7 Sessions spread over 7 weeks (BMS_P2_A):

  • 13 November
  • 20 November
  • 27 November
  • 4 December
  • 11 December
  • 18 December
  • 15 January

Edition 2 with 7 Sessions spread over 7 weeks, from 9:00-17:00h (BMS_P4_A):

  • Monday 10 May
  • Monday 17 May
  • Monday 31 May
  • Monday 7 June
  • Monday 14 June
  • Monday 21 June
  • Monday 28 June

Communicating Life Sciences

Period (from – till): 10 September 2020 – 19 November 2020 (P1) and 26 November 2020 – 18 February 2021 (P2)
Faculty
Course coordinator: Kirsten Koymans, PhD, programme advisor BMS, UMC Utrecht: k.j.koymans@umcutrecht.nl
Lecturer: Connie Engelberts, MSc, freelance science editor
Course description
During this course, the participants will write and edit articles that can be shared with the Graduate School of Life Sciences. The course starts with three meetings in which the students learn to identify interests of their target group, practice interview techniques and exercise in popular science writing. In the second half of the course, the students will choose at least three subjects to write upon, featuring Utrecht Life Sciences research and other topics that are relevant for the community of the Graduate School. They will edit each other’s work and find ways to promote their news articles.

The course is available for 4-12 students.

Until 2018 students published the Master for life magazine. Previous issues of Master for life magazine can be found here.

Programme (BMS_P1_A)10-9-2020Thursday13:1517:0017-9-2020Thursday13:1517:001-10-2020Thursday13:1517:0015-10-2020Thursday13:1517:0029-10-2020Thursday13:1517:0019-11-2020Thursday13:1517:00
Programme (BMS_P2_A)
26-11-2020 Thursday 13:15-17:00
03-12-2020 Thursday 13:15-17:00
17-12-2020 Thursday 13:15-17:00
14-01-2021 Thursday 13:15-17:00
28-01-2021 Thursday 13:15-17:00
18-02-2021 Thursday 13:15-17:00

Literature/study material
N.A.
RegistrationYou can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
Registration is on a "first come, first served" basis. The maximum number of participants is 10, with a minimum of 4.

Mandatory for students in own Master’s programme:
N.A.

Optional for students in other GSLS Master’s programme:
Yes.

Engaging Scientists with the Public (online course)

Period (from – till): This course is taught 2 times: Period 2 (BMS_P2_A) 9 november 2020 - 31 januari 2021 and Period 4 (BMS_P4_A) 26 april 2021 - 4 juli 2021​.

Course coordinator: Drs. Frans van Dam (|f.w.vandam@uu.nl)

Course description
“Public engagement describes the myriad of ways in which the activity and benefits of higher education and research can be shared with the public. Engagement is by definition a two-way process, involving interaction and listening, with the goal of generating mutual benefit” says the Utrecht University’s public engagement website. In the past five to ten years, universities have started to value public engagement. Universities feel they should be open to society. Not as mere providers of knowledge but they should also actively involve citizens, school children and stakeholders in their research and higher education.
Public engagement has many forms, from science fairs, special apps to patient consultations or data gathering. Activities of public engagement are aimed at a large variety of audiences, including patient groups, homeless people, school children or wider audiences. Key is that both, the researcher and his/her audience benefit from the interaction. Examples of these activities can be found on the UU-website: https://www.uu.nl/en/organisation/public-engagement-at-utrecht-university/what-is-public-engagement.
In this online course, students will design a public engagement activity. For that purpose they will select a research topic in connection with a Utrecht University research group or a particular researcher of their choice. In the first weeks, students will deepen their understanding of the complex relationship between science and society, the roles of scientists and the audiences for public engagement activities. Starting in week 4 students start performing the analyses needed for designing and evaluating their public engagement activity with follow-up in weeks 5-7. At the end of the course, in week 8-10, each student will finish his/her written plan for a public engagement activity and present it online.

Didactic approach
In this course, students develop a plan, based on theory, practical insights, and analyses. Peer feedback is a crucial aspect of the course, as giving and receiving feedback is a great help in improving the assignments. The weekly assignment will have to be finished on time to allow proper feedback.
This online course contains clips, reading materials, assignments, statements and reflections. In addition, students will be asked to contact a researcher and members of the audience they have selected. All of the weekly learning units can be carried out at home, using a computer and internet.
The lecturer is also moderator of the online course. He will assist the students and monitor the assignments and quality of the peer feedback.

Registration:
The registration is via Osiris Student. Please find additional information about the registration on the Study Guide.

Mandatory for students in own Master’s programme:
No

Optional for students in other GSLS Master’s programme:
Yes

Prerequisite knowledge
None.

English for Academic Purposes (online course)

Period (from – till): Eight times a year, 2 groups per period. The exact dates are displayed in the table below.

Faculty
Teachers from Babel Talen, Utrecht
For course content related questions or contact with Lecturers, please contact Alison Brown (cursuscoodinatie@babel.nl).
For matters regarding the GSLS and course registration, please contact the GSLS course coordinator coupled as contact person to this course.

Course description
The Babel Language Institute organises an 'English for academic purposes' course specifically for Life Sciences students. You can take this course as part of your elective component.

This English for Academic Purposes course focuses on giving academic presentations and writing an academic paper. The students’ own subjects will be used as a basis for language work. We will consider some essential elements of a presentation: opening, closing, signposting the organisation, referring to visuals, handling questions, adopting the right body language, and involving the audience. Students will learn how to give feedback and will improve their oral fluency and their vocabulary throughout the course.
Furthermore, we will focus on language aspects relating to writing an academic paper. We will analyse its information and look at language conventions. Moreover, we will discuss some issues involving punctuation, formal and informal English, wordiness and the use of linking words.
This course aims to develop and improve the writing and presenting skills students need in their master programme. In addition, students will activate and expand their vocabulary and improve their fluency in English.

During the course period, 10 online meetings of 2 hours will take place. Students need to invest 3-5 hours of self-study per week. A list with all the exact dates for the online meetings during the whole year can be found in Osiris. All online meetings are scheduled from 19:15-21:15h.
Students will pass the course if they attend at least nine meetings, have given a presentation, and have handed in a paper.
Literature/study material used
Textbook (writing and presenting scientific papers) and where appropriate, PDFs or weblinks (for example to grammar exercises) will be shared with students with supplementary information or materials.
RegistrationRegistration is on a "first come, first served" basis. Registration for the courses will be through OSIRIS Student. In the table below the corresponding registration periods for each edition have been added under the group number, to indicate which one you should use when registering via Osiris Student. More information about the registration procedure can be found here on the Studyguide.The maximum number of participants per group is 10, the minimum 6.
Mandatory for students in Master’s programme
N.A.

Optional for students in other GSLS Master’s programme:
Yes.

Prerequisite knowledge
The English proficiency is of an upperintermediate to advanced level.

Teaching Schedule:

The course is taught online from 19:15 – 21:15. Before the start of the course the teacher (Babel) will send you information about the online learning environment.Group:group 1group 2group 3group 4group 5group 6group 7group 8Osiris:BMS_P1_ABMS_P1_BBMS_P2_ABMS_P2_BBMS_P3_ABMS_P3_BBMS_P4_ABMS_P4_B Monday Tuesday Monday Tuesday MondayTuesdayMondayTuesday 131-8-20201-9-20209-11-202010-11-20208-2-20219-2-202126-4-20214-5-202127-9-20208-9-202016-11-202017-11-202015-2-202116-2-20213-5-202111-5-2021314-9-202015-9-202023-11-202024-11-202022-2-202123-2-202110-5-202118-5-2021421-9-202022-9-202030-11-20201-12-20201-3-20212-3-202117-5-202125-5-2021528-9-202029-9-20207-12-20208-12-20208-3-20219-3-202131-5-20211-6-202165-10-20206-10-202014-12-202015-12-202015-3-202116-3-20217-6-20218-6-2021712-10-202013-10-202011-1-202112-1-202122-3-202123-3-202114-6-202115-6-2021819-10-202020-10-202018-1-202119-1-202129-3-202130-3-202121-6-202122-6-2021926-10-202027-10-202025-1-202126-1-202112-4-20216-4-202128-6-202129-6-2021102-11-20203-11-20201-2-20212-2-202119-4-202113-4-202112-7-20216-7-2021reserve9-11-202010-11-20208-2-20219-2-202126-4-202120-4-202119-7-202113-7-2021reserve16-11-202017-11-202015-2-202116-2-20213-5-20214-5-2021 20-7-2021

Essentials of Neuroscience

Period (from – till):
Essentials of Neuroscience Face-to-face course: 18 January - 29 January 2021 (BMS_P2_B).
Essentials of Clinical Neuroscience Online course: 9 November 2020 - 24 January 2021 (BMS_P2_A).
Faculty
Ramakers, Adan, Burbach, Pasterkamp, Hol; UMC Utrecht Brain Center, Department of Translational Neuroscience.
Course descriptionOverall aim
The aim of the course is to provide sufficient background in molecular and cellular neuroscience to understand mechanisms underlying psychiatiric and neurological diseases.

Description of the Essentials of Neuroscience Face-to-face course:
This intense two weeks course is intended for non-neuroscience master students who want to get more background into neuroscience. The lectures during the course cover a broad range of neuroscience topics from gene to neurological disease and include neuro-anatomy, neurodevelopment, synaptic plasticity, neurogenetics and diseases. The lectures are given by experts from the UMC Utrecht Brain Center. During the afternoons the students will work in couples on an assignment on a neurological disease. This assignment will results in a scientific presentation of a research proposal on the disease, which will discuss all aspects covered in the lectures, ranging from clinical symptoms and treatment, to molecular and cellular mechanisms, to genetic studies and genes involved. These presentations will be held on the last Friday during a symposium.

Description of the Essentials of Clinical Neuroscience Online course:
This online course gives you a unique opportunity to study the state of the art insights in Neurosciences, discover the research strengths of UMC Utrecht and experience our educational philosophy. Wherever you are, you can join our academic community of eager, young minds from behind your computer!
The course will consist of web lectures by renowned experts as well as articles, group assignments, individual assignments, peer feedback and feedback from teachers. During the course you will interact with other participants through assignments and discussions. The course will be moderated actively by professional moderators and teaching staff of the Brain Center Rudolf Magnus of UMC Utrecht.

Literature/study material used:
Parts of Neuroscience (Purves et al., Sinauer Ass.Inc., Sunderland, Massachusetts, 4e editie, 2004 (ISBN 978-0-87893-697-7)) and recent reviews and original articles.

Registration:
Essentials of Neuroscience Face-to-face course: You can register for this course via Osiris Student via BMS_P2_B. More information about the registration procedure can be found here on the Studyguide. The maximum number of participants is 40.
Essentials of Clinical Neuroscience Online course: You can register for this course via Osiris Student via BMS_P2_A. More information about the registration procedure can be found here on the Studyguide. The maximum number of participants is 16.

Mandatory for students in own Master’s programme:
BoD students: This course is one of the specific cardiovascular BoD-courses. Additional to the mandatory Kick off course, BoD students should accomplish 12 EC with specific (cardiovascular) BoD courses.
This is not applicable for the online variant of this course.

Optional for students in other GSLS Master’s programme:
Yes, except for NSCN students.

Prerequisite knowledge:
No special requirements.

Food for Health and Safety

Period (from – till): 1 February 2021 - 1 July 2021.
Please be aware of selecting the correct course code based on your current studies:
this course is taught at Master level, but also open for 3rd year Bachelor students.
Master students should register for this course (BMB520220).
Bachelor students should register for the Bachelor variant of this course (BMB620220).

Course Coordinator: ing. Michèle Gerbrands MA (m.c.gerbrands@umcutrecht.nl)

Faculty
Lecturers, insprational speakers, workshop moderators, domain experts, coaches and others involved will be recruited from the participating universities, the ministries of Defence, Economic Affairs and Climate and from the governmental and corporate world.

Description of content
This course is built on the principles of challenge-based learning and is a collaboration of the alliance (UU, WUR, UMCU and TUe) and the Ministries of Defence and Economic Affairs and Climate.

Students from the UU, WUR and TUe will collaborate in interdisciplinary teams to solve a real-world problem while working on their personal and professional skills.
Each student team will develop a new food concept for the army.
The course consists of inspiring masterclasses and inspirational sessions given by professionals from the educational, governmental and corporate world, exciting team-building activities and individual coaching on the project and personal development. Students can broaden their network, collaborate with peers from different universities and get acquainted with the work field!

The course is given in a blended form and consists of 4 face to face events which are mandatory. Between these events, student teams can use an online learning environment, arrange meetings with their (team)peers, coach and experts.
Timetable
The challenge consists of 4 events, that take place over the course of 11 weeks. Each event will take place at a different location throughout the Netherlands. Next to these events online learning activities and meetings with the teamcoach and tutor take place.

Note that the duration of every event is the whole day, meaning 09:00 - 21:00 (including sleepover during the first event)! Sleepover is not mandatory.

Literature/study material used
-

RegistrationStudents from WUR and TUe can apply for the course on the website https://www.f4hs.nl/apply. They will be registered as guest students in the UU Osiris system.
Students from the UU must enroll in Osiris.
Twenty students from each university can register for this challenge.
Every bachelor year 3 and master student can apply. Please select the correct course code to register in Osiris! BMB520220 for Master students and BMB620220 for 3rd year Bachelor students.
Students will be registered based on a first come, first serve base.

Requirements:
The student is registered at the UU, WUR or TUe.
Is a bachelor year 3 or master student.
The student delivers a motivational letter. More information can be found on https://www.f4hs.nl/apply
After registration the student receives a questionnaire for a Belbin test. This will give the student more insight in team roles.
The results of all the participating students will be used to form complementairy teams.
You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.

Mandatory for students in Master’s programme
N.A.

Optional for students in other GSLS Master’s programme
Yes, open for students registered at the UU, WUR or TUe.

Prerequisite knowledge
No prerequisite knowledge is needed or required. Motivation is a key factor in participating in this challenge.

Fundamentals of Biofabrication, online course

Note: this is an online course stretching over 9 weeks with a study load of approximately 10 hours per week. The course contains weekly deadlines for group and individual assignments, as well as constant participation and peer interactions in group discussions. Students should take this into account when registering for the course based on other workload (courses/internships).

Period: 16 November 2020 - 29 January 2021 (2-week Christmas holiday)

Course coordinator: Paulina Nunez Bernal, MSc. (p.nunezbernal@umcutrecht.nl)​
Lecturer: Paulina Nunez Bernal, MSc. (p.nunezbernal@umcutrecht.nl)​

Course content
Biofabrication combines advanced 3D fabrication techniques with biological systems to create designed tissue constructs, which can be applied for tissue engineering, as 3D in vitro biological models or as medical therapeutic products. This e-­course aims to provide the student with the fundamental knowledge on the various aspects of biofabrication, including 3D printing techniques, biomaterials, tissue engineering, applications, translation and ethics.

The subjects being addressed:

  • 3D printing history, techniques, applications
  • CAD/CAM, 3D modelling, STL, G-code
  • Medical imaging to printing
  • 3D printing techniques: additive manufacturing, robotic
    dispensing, fused deposition modelling, electrospinning,
    stereolithography, powder printing
  • 3D printing in the clinic: devices and implants
  • Biomaterials: polymers, bioinks, tissue­-derived matrices
  • Cells and stem cells
  • Cell printing
  • Applications: cartilage, liver, cardiovascular system,
    organ­-on-­a-­chip, in vitro models
  • Translation, bench-­to­-bedside
  • Automation, implementation, and regulation of these technologies
  • Ethics

The added value for the participants:
This course provides fundamental knowledge on biofabrication and is developed by a leading research group within the biofabrication field. Weblectures are given by experts in the fields of tissue engineering, materials science, mechanical engineering, medicine, biology and ethics.

Registration
You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
Students must send a short motivation letter (200-300 words) before the 27th of September, describing their reasons for taking the course, as well as their willingness to participate in its discussions and assignments and to meet deadlines. Please send this letter in an email to p.nunezbernal@umcutrecht.nl after completing the registration process via OSIRIS.

Entry requirements
None

History of Medicine and the Biomedical Sciences

Period (from – till): 9 February 2021 - 13 April 2021
Locations in the schedule are yet to be determined.

Student can register for this course after the registration deadline. Please contact the course coordinator.
Faculty:
Prof. dr. F.G. Huisman, Julius Centre UMC Utrecht
Course description:
This is a nine-week course that is part of the Research Master History and Philosophy of Science, offered by the Descartes Centre for the History and Philosophy of the Sciences and the Humanities. In principle, it is open to all MA students of the Graduate School of the Life Sciences.
Modern biomedical science and modern medicine originated - both epistemologically and institutionally – in the period between 1850 and 1950. The epoch not only witnessed the birth of the modern hospital and the laboratory, but there was a growing awareness that the state had an important role to play in public health as well. Taken together, the hospital, the laboratory and the caring state can be considered as the symbols of modernity.

Over the course of time, the medical scientist and the clinician have become valuable citizens, who transformed our health care system profoundly. At the same time, scientific progress has come with problems and drawbacks. In order to understand modern medicine and health care, it makes sense to take a look at its historical roots.
This course is an introduction to the birth of modern medicine, looking at developments over the course of the ‘long nineteenth century’. After an introduction of five weeks, you are expected to choose a topic that particularly interests you and write a paper about it. Topics may be chosen from any period between Classical Antiquity and contemporary biomedicine.
You will find out that history is not about presenting dry facts about the past, but rather about reflecting the human condition. Medical history is thinking about the ways in which man is dealing with health and illness, with pain and death – both in the past and in the present.

The full description can be downloaded here.

Literature/study material used:
- K. Codell Carter, The rise of causal concepts of disease (Aldershot: Ashgate, 2003), vii-ix and 1-9
- Ch. Rosenberg and J. Golden eds., Framing disease. Studies in cultural history (Rutgers UP, 1992). xii-xxvi.

- D. Wootton, Bad medicine. Doctors doing harm since Hippocrates (Oxford University Press, 2006), 1-26.
- S. Shapin, ‘Possessed by idols’, London review of books, 30 november 2006. See http://www.lrb.co.uk/v28/n23/steven-shapin/possessed-by-the-idols (including Wootton’s response).

- W.F. Bynum, Science and the practice of medicine in the nineteenth century (Cambridge: Cambridge University Press, 1994).

- M. Jackson ed., The Oxford handbook of the history of medicine (Oxford: Oxford university press, 2011):
* R. Cooter, ‘Medicine and modernity’ (pp. 100-116)
* H.J. Cook, ‘Medicine in western Europe’ (pp. 190-207)
* M. Gorsky, ‘The political economy of health care’ (pp. 429-449)
* R. Bivins, ‘Histories of heterodoxy’ (pp. 578-597)

- Chr. Hamlin, Cholera: the biography (Oxford UP, 2009).

Schedule:
PART 1
Week 7 (Tuesday 9/2/2021) – Introduction to the course and discussion of the introductions to Codell Carter, The rise and Rosenberg, Framing disease (HvdB-room xxx)
Week 8 (16/2) – Discussion of Bynum, Science, ch. 1-4, Wootton, Bad medicine and the review by Shapin (HvdB-room xxx)
Week 9 (23/2) – Discussion of Bynum, Science, ch. 5-8 and Loudon (HvdB-room xxx)
Week 10 (2/3) – Discussion of four texts taken from Jackson ed., The Oxford handbook and Booth, The craft (HvdB-room xxx)
Submit preliminary research question and outline for review
Week 11 (9/3) – Discussion of Hamlin, Cholera and Rawlins, The writer’s way (HvdB-room xxx)
Submit final research question, outline and bibliography

PART 2
Week 12 (16/3) – Discussion of research plans (HvdB-room xxx)
Week 13 (23/3) – Discussion of research plans (HvdB-room xxx)
Week 14 (30/3) – Discussion of research plans (HvdB-room xxx)
Week 15 (6/4) – Optional (HvdB-room xxx)
Week 16 (13/4) – Colloquium and oral presentation of paper (HvdB-room xxx)
Submit final written paper
Please post your power point presentation to the coordinator by 5 PM on 12 April 2021

During the first part of the course, students are expected to send (each week) three observations and three questions, based on the readings, by email to the others (no later than 5 pm, the day before the next session). During sessions, the pre-circulated questions and observations will be discussed.

During the second part of the course, everybody presents his or her work in progress. Every week, you are expected to email a one page outline to the others no later than 5 pm the day before the next session. During those sessions, students are taking turns in giving an oral presentation of half an hour (also including discussion).

Time and location
Time: on Tuesdays, 13.15-17.00 (= 1.15 p.m. to 5 p.m.).
Location: Heijmans van den Bergh Building (HvdB), Uithof (to be reached by bus no. 12 or 28). Rooms differ (power point facilities are available everywhere).
Paper presentations: 11.00-17.00

Registration:
The maximum number of participants is 15. Please register via Osiris Student in Period 3 (Please note that this is a small exception in regards to start dates and corresponding Period. Use starting block BMS P3 A). More information can be found here in the Study guide.
Student can register for this course after the registration deadline. Please contact the course coordinator.

Mandatory for students in own Master’s programme:
N.A.

Optional for students in other GSLS Master’s programme:
This course is an elective course for all Master’s student of the Graduate School of Life Sciences. It is open to all students enrolled in the Research Master History and Philosophy of Science.

Prerequisite knowledge:
Bachelor’s degree and admission granted to a GSLS Master’s programme or Research Master History and Philosophy of Science.

Introduction to Designing & Teaching in Higher Education

Period (from – till): 12 Febuary 2021 - 16 April 2021, end date optional internship/paper 1 July 2021

Faculty
Dr. Renske de Kleijn, UMCU, Onderwijscentrum, BMS 50%
Dr. Rianne Bouwmeester, UMCU, Onderwijscentrum, BMS 30%
Heleen van Ravenswaaij MSc, UMCU, Onderwijscentrum, BMS 10%
Dr. Kirsten Koymans, UMCU, Onderwijscentrum, BMS 10%

Course descriptionWhen pursuing a career in academia, you will most likely also be confronted with teaching activities at some point in time. This course will give you the opportunity to explore whether teaching in higher education is something that has your interest.
This elective course consists of three elements.

Important: this is a part-time course that can be taken together with other study components. The studyload for the theoretical part is approximately 8 hours per week. The educational internship and writing assignment can be planned more flexible (more or less hours/week) together with your supervisor, depending on your study schedule and supervisor availability.

  1. Theoretical foundations (3 EC) obligatory
  2. Educational internship (3-6 EC) optional
  3. Educational writing assignment (1.5-3 EC) optional

Obligatory part:
For the Theoretical foundations there are 9 weekly meetings in which educational theories and practical tools are discussed. These two hour meetings are scheduled on Friday morning at 10 o’clock. For each meeting students prepare literature and watch video clips (see also Literature/study material used). The workload per meeting is approximately 8 hours. The meetings concern themes such as teaching roles, constructive alignment, the design of an educational meeting, evidence-based educational design strategies, motivation and self-regulation, online and blended education, giving and using feedback, rubrics, and transparency, validity, and reliability of assessment. During the meetings, students teach a small learning activity to their peers and reflect on this (20%) and in meeting 8 students give a presentation (20%) on what they have learned during the course. To conclude the Theoretical foundations, during the final meeting an open book exam, encompassing the content of the meetings, will be held (60%).

Optional parts:
Educational internship
Students can decide to extend this elective course with an Educational internship of 3 or 6 EC (2 or 4 weeks). During such internship students can teach a work group, design an educational element for a specific course, write an advice report for a course coordinator, etc. Preferable these internships take place in dyads and in a successfully completed course from GSLS, Biology, or BMW. There will be pre-defined internships, but students are also free to find an internship assignment independently. For the internship students are assessed by their internship supervisor on their practical work (60%) and on their internship report by a course teacher (40%).

Educational writing assignment
Students can also decide to extend the elective course with an individual Educational writing assignment for 1.5 or 3 EC (1 or 2 weeks). They can choose any educational topic. Every student provides feedback to another student on a draft version (20%), writes a feedback report on how peer and teacher feedback on the draft were used (20%), and is assessed on the final paper (60%).

Schedule

  1. Friday morning 12 Feb
  2. Friday morning 19 Feb
  3. Friday morning 26 Feb
  4. Friday morning 5 March
  5. Friday morning 12 March
  6. Friday morning 19 March
  7. Friday morning 26 March

No meeting on Friday 2 April

  1. Friday morning April 9
  2. Friday morning April 16

Literature/study material used
For each meeting 1-3 short scientific papers need to be prepared, as well as watching 1-3 informative video clips. For some meetings a small additional preparatory assignment is given.
RegistrationYou can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
The optional parts are registered separately based on decisions during the obligatory part.
Mandatory for students in Master’s programme
N.A.

Optional for students in other GSLS Master’s programme:
Yes, for all GSLS students.

Prerequisite knowledge
-

Laboratory Animal Sciences

Period (from – till): several times a year.
Faculty
Teachers from the Department of Animals in Science and Society , Faculty of Veterinary Medicine, University Utrecht
NOTE: There are different courses offered, please read the information on the websites carefully. You should take the laboratory animal sciences course only if you need it for your research project; you must have permission from your supervisor and your programme coordinator.

You can find the exact course dates and information for the English taught course here.
More information about the Dutch taught course can be foud here.

Course description
This course is a requirement for conducting animal experiments and teaches you the basics on animal research.
The objective of the course is to present basic facts and principles that are essential for the humane use and care of animals and for the quality of research. From the beginning of the course, emphasis is placed on the fact that the scientist is the central person in the design and performance of animal experiments, and that he/she has specific responsibilities with respect to the welfare of the animals used. It is made clear that the use of animals can be accepted only under a set of strict conditions. Among these are that the experiment must be approved by an ethics committee, and must be conducted by persons who are fully competent.
Please note:

  • You should take the laboratory animal sciences course only if you need it for your research project; you must have permission from your supervisor and your programme coordinator.
  • Because this course is expensive, you need to fill the rest of your elective component with modules which are free of extra costs, in exceptional cases more than one course may be allowed. You have to ask prior approval from the Board of Examiners if you want to take more than one of these courses.

Registration:

Fill out the form and first hand it in at your Master's programme’s administration desk for approval. You need a signature and financial account number in order to have the form accepted at the LAS administration. In order to get approval from the Board of Examiners please add a signed statement of your examiner that this course is mandatory for your researchproject. After obtaining the approval you can sent the form to the LAS administration.

Mandatory for students in GSLS Master’s programme
No.

Optional for students in GSLS Master’s programme
Yes.

Career Orientation & Professionalisatio

This course is in Dutch only.
Deze cursus is o.a. gericht op persoonlijke groei en het verder ontwikkelen van een aantal communicatieve managementvaardigheden: persoonlijk leiderschap.
De kwaliteit en diepgang vragen om zorgvuldigheid en nuance bij feedback en zelfreflectie. Daartoe gebruiken we voor Nederlandse studenten de Nederlandse taal.
Voor internationale studenten is er een Engelstalige variant in de periodes 2 en 4.
De Nederlandse cursus wordt sinds 2001 gegeven door Jan van den Broek, managementtrainer en o.a. werkzaam bij de Bètafaculteit van de Radboud Universiteit Nijmegen.

Let op:
In de periodes 2 en 4 wordt van deze cursus tegelijkertijd ook een Engelstalige variant aangeboden (BMB522319). Beide cursussen staan dan open voor inschrijving. Mocht het totaal aantal aanmeldingen voor beide cursussen niet voldoende zijn om beide cursussen parallel te kunnen aanbieden, dan krijgt de Engelse cursus voorrang. Studenten van de Nederlandse cursus wordt dan gevraagd deel te nemen aan de Engelstalige variant.’

Nanomedicines

Characteristics of nanoparticles such as size, surface area and internal composition make them attractive candidates for use in therapeutic and diagnostic applications. The aim of this course is to provide an overview of the nanomedicine field. Every week a theme will be discussed in which nanomedicine is involved: therapeutics (both synthetic and bio-inspired) and diagnostics. We will focus on the applications of nanomedicine in cancer and cardiovascular disease.

After an introductory lecture on a specific theme, you will have an interactive meet up with experts of the field. During the week you will work on an assignment together with other students (as a group). During the course you will write a research proposal, present a paper and present the unique selling point of a nanomedicine company.

Online Course Radiation Protection – ELO on Open Sources

Period (from – till): Several times a year. The exact dates will be published on the website of NCSV.

Contactperson: Opleid-U-NCSV-RID@tudelft.nl t.a.v. Mw. Peeters​

Faculty
S. (Silvia) Bijland, Bètawetenschappen, NCSV
M.N. (Madeleine) Eikeboom, Bètawetenschappen, NCSV
H.J. (Marina) Gaikhorst, Bètawetenschappen, NCSV
W.F. Wiersma, PhD, head of the training centre/tutor in Utrecht, NCSV
Course description
This Online Course (in Dutch) provides theoretical knowledge about radiation protection to work in a laboratory in which open sources of radioactive materials are used. It is a set of web-based Radiation Protection modules with an accompanying test. Participants must complete the modules and successfully pass this test and will receive a certificate of participation.
This course covers only the theoretical aspects of radiation protection. To be able to work under the supervision of a radiation protection officer (TMS) with radioactive open sources (e.g. in a lab) it is also necessary to get a practical instruction at the workspace. Literature/study material
Optional: Book: Practical Radiation Protection by Jos van den Eijnde & Lars Roobol EAN: 9789491764301
(Dutch publication Praktische stralingshygiëne, ISBN 9789491764295).

Registration
To register:
1. First fill in the General application form for electives to get your application approved by the GSLS;

2. After approval register on the NCSV website (Contactperson: Opleid-U-NCSV-RID@tudelft.nl t.a.v. Mw. Peeters).

Mandatory for GSLS students.
No.
Optional for students from other GSL Master's programmes:Yes.

Prerequisite knowledge:
The course is based on participants with a technical, medical or scientific education on university level. A good knowledge of physics, chemistry and mathematics is necessary.

Philosophy of Neuroscience

Period (from - till): Period 4 (1 - 30 June 2021)

Course description
This course is offers compact, rigorous and practical journey in the philosophy of neuroscience, the interdisciplinary study of neuroscience, philosophy, cognition and mind. Philosophy of neuroscience explores the relevance of neuroscientific studies in the fields of cognition, emotion, consciousness and philosophy of mind, by applying the conceptual rigor and methods of philosophy of science. The teaching will start with the basics of philosophy of science including the work of Popper, Lakatos, Kuhn and Feyerabend, and use a methodological evaluation scheme developed from this work that allows rigorous evaluating neuroscientificresearch as science or pseudoscience. Furthermore, there will be attention for the historical routes of neuroscience starting with Aristotle, and the conceptual problems in neuroscience, methodological confusions in neuroscience, dualism and fysicalism. The main aim of the course is provide wide-ranging understanding of the significance, strengths and weaknesses of fields of neuroscience, which helps in critical thinking, creativity, methodological precision and scientific writing.

Literature/study material used
Book Chapters and Articles on Neurophilosophy and Philosophy of Neuro(science).
Registration
You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide. Max. 25 students per edition.

Mandatory for students in own Master’s programme:
No

Optional for students in other GSLS Master’s programme:
Yes

Science and Society

Period (from – till): 8 January 2021 - 4 June 2021
Note: The Course schedule is: January 8, February 26, March 12, May 7, June 4 and optional date November 26 (a lecture from the PhD course open for students of this course), 2021. The exact schedule of lectures is available in the detailed desciption through the link below. Locations will follow at a later date.
Please send an email to Ms M. van Dijk-Okla: m.vandijk-okla@umcutrecht.nl including a short motivation and requested information.

Faculty
Prof. dr. F.G. Huisman, Julius Centre UMC Utrecht;
Dr Annemieke Meijer (UCU)
Dr. Sander Werkhoven (Ethics Institute)
Dr. Leon Knippels (Danone/Nutreicia)
Guest lecturers
Course description
A detailed description of the course can be found here on the Study Guide.

In modern life, science is everywhere. The products of biomedical science and technology may help achieve a healthy society and economic progress. They may even prolong life and make it more agreeable at the same time. But how much do we really know about the production, implementation and evaluation of scientific knowledge? What, exactly, is the basis for our belief in science? What sets it apart from common knowledge? Who should we trust in case two scientists disagree in a hotly debated issue? Is science a vocation or just another profession? Is scientific knowledge something special to be emulated, or ‘just another opinion’? Are scientific facts discovered or socially constructed? How are science and technology embedded in society and how do they change over time?

Whoever wants to become a scientist, should be aware of these and similar questions; (s)he should not just know about the contents of scientific knowledge, but about its context as well. This course sets out to create that awareness. Until recently, it was only available to PhD students. Now, an abridged version is offered to graduate students. In six Friday afternoon sessions, the historical, philosophical, sociological and ethical dimensions of the biomedical sciences will be discussed.

For those of you who are interested in a public debate that is now going on with regard to science and the university, see www.scienceintransition.nl and http://www.wetenschapsagenda.nl/.

The course will be assessed by means of a writing assignment: you will be asked to submit a 1500 word paper on any topic, related to the theme of the course.

You will write an argumentative essay: one in which you discuss a controversial issue, take up a position and give supporting arguments aimed to persuade your readers to accept your claim(s). It is different from the types of text that you may be used to writing (lab reports, research papers) in that the writer has a clear voice – he or she is present in the text, which allows for (or indeed, requires) a considerable amount of creativity and personal choice. You may use a variety of sources, both scholarly and popular (newspapers, magazine articles).

Your essay will be graded on the basis of the following criteria:

  • information: detailed, accurate, relevant
  • structure: rigorously argued, logical, easy to follow
  • interpretation: evidence of independent thought and critical analysis
  • use of evidence: key points supported with evidence, critically evaluated
  • academic referencing: good use of academic referencing conventions
  • style & use of language

Literature/study material used:
Three articles, taken from the Golem-series by Harry Collins and Trevor Pinch:

- ‘Introduction: the Golem’ and ‘The Germs of Dissent: Louis Pasteur and the Origins of Life’ in: Collins and Pinch, The Golem. What You Should Know about Science (Cambridge UP 1993), 1-3 and 79-90.
- ‘ACTing UP: AIDS Cures and Lay Expertise’ in: Collins and Pinch, The Golem at Large. What You Should Know about Technology (Cambridge UP 1998), 126-150.
- ‘Vaccination and Parents’Rights. Measles, Mumps, Rubella (MMR), and Pertusis’ and ‘The Themes Revisited’ in: Collins and Pinch, Dr. Golem. How to Think about Medicine (The University of Chicago Press 2005), 180-204 and 205-224.

In addition to these articles, speakers will provide one or two articles on the topic of their lecture. When possible, we will send an email with these attachments before the meetings, so that you can prepare the topics to be discussed. Students should print the documents themselves.

Registration:
The Course schedule is: January 8, February 26, March 12, May 7, June 4 and optional date November 26 (a lecture from the PhD course open for students of this course), 2021. The exact schedule of lectures is available in the detailed desciption through the link below. Locations will follow at a later date.
Please register via Osiris Student in Period 2 (Use starting block BMS_P2_A). More information can be found here. In order to register, please send an email to Ms M. van Dijk-Okla: m.vandijk-okla@umcutrecht.nl, including the following information:

  • Course name
  • Name
  • Student number
  • Email address
  • A short motivation

The maximum number of students is 30.
All Master’s students of the Graduate School of Life Sciences are welcome to attend the course. There is, however, a maximum capacity of 30 participants. Should there be more applicants, the final 30 will be selected on the basis of their application letter.
You are expected to be an active participant, i.e. to prepare the topic and to take part in the general discussion.
Please send an email to Ms M. van Dijk-Okla: m.vandijk-okla@umcutrecht.nl including a short motivation and requested information.

Mandatory for students in own Master’s programme:
N.A.

Optional for students in other GSLS Master’s programme:
Yes.

Prerequisite knowledge:
Bachelor’s degree and admission granted to a GSLS Master’s programme

Societal Challenges for Life Science Scientists: Exploring Interdisciplinarity

Period (from - till): 11-22 January 2021

Course coordinators:
Dr. ir. M.E.G.L. Lumens
Dr. G.M.J. Ramakers

Course description:
One overarching interdisciplinary theme will be chosen each year. This year the theme is Food and health. In the first few days, lecture/discussion will be organized with experts in the field to help students familiarize with the topic, get an overview of the current debate, and the problems to solve. In the meantime, students will be instructed on the principles of interdisciplinary research.
Students form interdisciplinary groups of 3/4 and develop a research question within the theme that captured their interest. After presenting their plans and receiving (peer) feedback on the feasibility of their plans, students make a concrete plan for the rest of the course period and divide tasks. Each team has a supervisor.

Examination:AssessmentDescriptionWeightONDERZResearch proposal40%OPDRACHTAssignment30%PRESENTPresentation30%
Literature/study material used:
-
Registration
You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.

Mandatory for students in own Master’s programme:
N.A.

Optional for students in other GSLS Master’s programme:
Yes.
Prerequisite knowledgeStudents should be enrolled in a master's programme of the Graduate School of Life Sciences.

Thematic Interdisciplinary Challenge

Enrolment
Please note! For this course deviant enrolment rules apply:
A maximum of 60 students (20 per TIC) will follow the course together with 15 professionals. As a student, you are asked to tell us your story when you apply for the TIC course via our website. When applying, you can also indicate which TICs you prefer to explore and which TIC is your second choice.
You can apply for the course before the 22nd of November 2020 (via our website). On the 24th of November 2020 you will be notified whether you can participate in this course. If you are not selected, you can register for another course until November 29, 2020. If you have been selected, you will automatically be registered for the course.

ontent description
Today’s world faces a lot of complex societal problems. These problems demand the input of multiple academic disciplines. Therefore, in the TIC course, students and professionals will be challenged and trained to become interdisciplinary and innovative problem solvers that contribute to solutions for real-world and complex societal problems.

Starting February 2021 the Thematic Interdisciplinary Challenge (TIC) is a university-broad course for year-3 Bachelor students, Master students and professionals from different disciplines. The course will promote interdisciplinary and cross-level collaboration while solving real-world challenges within the strategic themes of Utrecht University.

Students and professionals will be asked to choose one Thematic Interdisciplinary Challenge they would like to explore: Drowning Deltas, Green Teens or Contesting Governance. More information about these TICs can be found on our website: https://tic-to-tic.sites.uu.nl/

The course will offer a mix of expert sessions, workshops and discussions. In interdisciplinary groups of 4-5 students and professionals, you will learn to apply theoretical knowledge in order to solve real-world challenges.

One line of workshops will guide you through different stages from defining to solving the problem. Students and professionals from various fields will work together with scientists and policymakers towards a suitable end-product that contributes to an innovative solution of the jointly defined problem. The solution could be a prototype, a video, a symposium, a policy document, etc.

Another line of workshops will be directed towards (inter)personal and professional development. The course format creates a space to discover yourself and use your curiosity, enthusiasm, and creativity to come up with innovative ideas that contribute to the needs of today’s society.

Educational forms
The course consists of, among other things, debates, group work, workshops, lectures, presentations, projects, problem based learning and a symposium.

Grading
No written exam. The final grade is the result of active participation (pass or fail), the solution proposal and implementation plan (30%; minimal grade 5.5), assignment (30%; minimal grade 5.5) and reflection essay (40%; minimal grade 5.5).

Study material
Peer-reviewed articles, book chapters, and popular scientific articles, which will be distributed at the start of the course.

Vascularized Tissue Engineering Online Course

Period (from – till): 8 February - 18 April 2021
Note: this is an online course stretching over 10 weeks with a study load of approximately 9-10 hours per week. Please take into account that the studyload is divided over the week so you will need to be able to login on various moments (taking into account vacation days).
The e-moderator will keep track of your progression. He/she will score the quality of the content and your responses on all required activities. This results in ‘insufficient, ‘sufficient’ or ‘good’. You need at least a 5.5 for all three individual components to pass the course. ​

Course coordinator: Dr. Caroline Cheng/Dr. Joost Fledderus
Lecturer: Merle Maas-Krebber, MSc

Course description:
Tissue engineering (TE) is an ever-growing multidisciplinary scientific field aiming at replacing injured, missing or damaged tissue. Current researchers in the field use different principles, knowledge and techniques from (stem) cell biology, vascular biology, medicine, biomaterials and bioengineering. Vascular and vascularized tissue engineering take prominent places within this field. The construction of blood vessels is both an independent target for replacement therapy as well as an integral part of larger constructs. A crucial challenge in obtaining large sized functional TE scaffolds (>1 milimeter in any dimensional space) is how to introduce a complex vascular tree that supplies a steady medium and blood stream for the expanding tissue to meet oxygen en nutrient demands.
This course teaches Master students’ in-depth and hands-on knowledge on developmental and adult blood vessel formation in health and disease and the current clinical treatments for which vascular(ized) TE is thought to be eligible. Moreover, we will address state of the art techniques of vascular(ized) TE, including the use of biomaterials and cell sources for bioreactor-cultured and in situ applications.

This course teaches fundamental knowledge on vascular and vascularized tissue engineering, adding significantly to the currently available curriculum concerning angiogenesis, vascular repair and remodeling, regenerative medicine and cardiovascular disease. Participants in this e-course will benefit from the flexible work hours, enabling participation parallel to writing a thesis or doing an internship abroad. This course was developed using collaborative partners leading in regenerative medicine and cardiovascular disease. Grading of this course will be based on handing in a graphical abstract (group assignment), an individual assignment and on individual participation during the course and in discussion forums.

Required Materials:
N.A.

Mandatory for students in Master’s programme:
N.A.

Optional for students in other GSLS Master’s programme:
Open as an elective to all GSLS students with priority for students from the programmes RM&T, BFAB & BOD.

Registration:
You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
Maximum number of participants is 16 students.
Students from outside Utrecht University can register for this course by sending an email to m.m.krebber-2@umcutrecht.nl. Please include your name, student number, Master’s programme and the course code.

Prerequisite knowledge:
Master student RMT, BOD, Biofab