Key publications:
- Cirillo, E.N.M., Nardi, F.R., Spitoni, C.
Metastability for reversible probabilistic cellular automata with self-interaction;
Journal of Statistical Physics, 132 (2008)
- Cirillo, E.N.M., Nardi, F.R., Spitoni, C.
Competitive nucleation in reversible probabilistic cellular automata
Physical Review E, 78 (2008)
- Spitoni, C., Verduijn, M., Putter, H.
Estimation and asymptotic theory for transition probabilities in Markov renewal multi-state models;
International Journal of Biostatistics, 8 (2012)
- Putter, H., Spitoni, C.
Non-parametric estimation of transition probabilities in non-Markov multi-state models: The landmark Aalen–Johansen estimator;
Statistical Methods in Medical Research, 27 (2018)
- van Enter, A.C.D., Kimura, B., Ruszel, W., Spitoni, C.
Nucleation for one-dimensional long-range Ising models;
Journal of Statistical Physics, 174 (2019)
- Lancia, G., Varkila, M.R.J., Cremer, O.L., Spitoni, C.
Two-step interpretable modeling of ICU-AIs;
Artificial Intelligence in Medicine, 151 (2024)
- Cirillo, E.N.M., Jacquier, V., Spitoni, C.
Particle transport based study of nucleation in a ferromagnetic three-state spin system with conservative dynamics;
Submitted (2024)
- Kamsma, T., van Roij, R., Spitoni, C.
A simple mathematical theory for Simple Volatile Memristors and their spiking circuits;
Chaos, Solitons and Fractals (2024)
- Jacquier, V., Ruszel, W., Spitoni, C.
Isoperimetric inequality for nonlocal bi-axial discrete perimeter;
Annales de l'Institut Henri Poincaré D (2026)
Publications
2026
Scholarly publications
Ruszel, W. M., & Spitoni, C. (2026). Topology, noise, and parallel updates in circular opinion dynamics. Manuscript submitted for publication. In Arxiv.org [DOI]
Jacquier, V., Ruszel, W. M., & Spitoni, C. (2026). Isoperimetric inequality for nonlocal bi-axial discrete perimeter. Annales de l'Institut Henri Poincare (D) Combinatorics, Physics and their Interactions. Advance online publication. [DOI]
Cirillo, E. N. M., Vliem, J. L., Schuricht, D., & Spitoni, C. (2026). Inefficiency of the block approximation in diploid Probabilistic Cellular Automata. arXiv. [DOI]
Kamsma, T., Gu, Y., Spitoni, C., Dijkstra, M., Xie, Y., & van Roij, R. (2026). Energy-efficient time series processing in real-time with fluidic iontronic memristor circuits. Faraday Discussions. Advance online publication. [DOI]
2025
Scholarly publications
2024
Scholarly publications
Lancia, G., & Spitoni, C. (2024). Constructing Interpretable Prediction Models with 1D DNNs: An Example in Irregular ECG Classification. arXiv. [DOI]
Jacquier, V., Cirillo, E. N. M., & Spitoni, C. (2024). Particle transport based study of nucleation in a ferromagnetic three-state spin system with conservative dynamics. arXiv. [DOI] [Repository]
Kamsma, T. M., Rossing, E. A., Spitoni, C., & Roij, R. V. (2024). Advanced iontronic spiking modes with multiscale diffusive dynamics in a fluidic circuit. Neuromorphic Computing and Engineering, 4(2), Article 024003. [DOI] [Repository]
Kamsma, T. M., Kim, J., Kim, K., Boon, W. Q., Spitoni, C., Park, J., & Roij, R. V. (2024). Brain-inspired computing with fluidic iontronic nanochannels. Proceedings of the National Academy of Sciences, 121(18), Article e2320242121. [DOI] [Repository]
Kamsma, T., Roij, R. V., & Spitoni, C. (2024, Feb). A simple mathematical theory for Simple Volatile Memristors and their spiking circuits. [DOI] [Repository]
Lancia, G., Varkila, M., Cremer, O. L., & Spitoni, C. (2024). Two-step interpretable modeling of ICU-AIs. Artificial Intelligence in Medicine, 151, Article 102862. [DOI] [Repository]
Kamsma, T. M., Rossing, E. A., Spitoni, C., & Roij, R. V. (2024). Advanced iontronic spiking modes with multiscale diffusive dynamics in a fluidic circuit. arXiv. [DOI] [Repository]
Cirillo, E. M. N., Jacquier, V., & Spitoni, C. (2024). Homogeneous and heterogeneous nucleation in the three-state Blume–Capel model. Physica D: Nonlinear Phenomena, 461, Article 134125. [DOI] [Repository]
2023
Scholarly publications
Kamsma, T. M., Boon, W. Q., Spitoni, C., & van Roij, R. (2023). Unveiling the capabilities of bipolar conical channels in neuromorphic iontronics. Faraday Discussions, 246, 125-140. [DOI] [Repository]
Lancia, G., Durastanti, C., Spitoni, C., De Benedictis, I., Sciortino, A., Cirillo, E. N. M., Ledda, M., Lisi, A., Convertino, A., & Mussi, V. (2023). Learning models for classifying Raman spectra of genomic DNA from tumor subtypes. Scientific Reports, 13(1), Article 11370. [DOI] [Repository]
Kamsma, T. M., Boon, W. Q., Rele, T. T., Spitoni, C., & Roij, R. V. (2023). Iontronic Neuromorphic Signaling with Conical Microfluidic Memristors. Physical Review Letters, 130(26), 1-7. Article 268401. [DOI] [Repository]
Lancia, G., Durastanti, C., Spitoni, C., Benedictis, I. D., Sciortino, A., Cirillo, E. N. M., Ledda, M., Lisi, A., Convertino, A., & Mussi, V. (2023). Learning models for classifying Raman spectra of genomic DNA from tumor subtypes. (pp. 1-19). arXiv. [DOI] [Repository]
Lancia, G., Varkila, M., Cremer, O., & Spitoni, C. (2023). Two-step interpretable modeling of Intensive Care Acquired Infections. (pp. 1-30). arXiv. [DOI] [Repository]
Kamsma, T. M., Boon, W. Q., Spitoni, C., & Roij, R. V. (2023). Unveiling the capabilities of bipolar conical channels in neuromorphic iontronics. (pp. 1-9). arXiv. [DOI] [Repository]
Kamsma, T. M., Boon, W. Q., Rele, T. T., Spitoni, C., & Roij, R. V. (2023). Iontronic neuromorphic signalling with conical microfluidic memristors. (pp. 1-9). arXiv. [DOI] [Repository]
2022
Scholarly publications
Cirillo, E. N. M., Jacquier, V., & Spitoni, C. (2022). Metastability of Synchronous and Asynchronous Dynamics. Entropy, 24(4), 1-18. Article 450. [DOI] [Repository]
Lancia, G., Goede, I. J., Spitoni, C., & Dijkstra, H. (2022). Physics captured by data-based methods in El Niño prediction. Chaos, 32(10), Article 103115. [DOI]
2021
Scholarly publications
2020
Scholarly publications
behalf of the MARS consortium (2020). Erratum: Predicting the clinical trajectory in critically ill patients with sepsis: A cohort study (Critical Care (2019) 2 (408) DOI: 10.1186/s13054-019-2687-z). Critical Care, 24(1), Article 41. [DOI] [Repository]
2019
Scholarly publications
Klein Klouwenberg, P. M. C., Spitoni, C., Van Der Poll, T., Bonten, M. J., Cremer, O. L., Frencken, J. F., Van De Groep, K., Koster-Brouwer, M. E., Ong, D. S. Y., Verboom, D., De Beer, F. M., Bos, L. D. J., Glas, G. J., Van Hooijdonk, R. T. M., Schouten, L. R. A., Straat, M., Witteveen, E., Wieske, L., Hoogendijk, A. J., ... Van Vught, L. A. (2019). Predicting the clinical trajectory in critically ill patients with sepsis: A cohort study. Critical Care, 23(1), Article 408. [DOI] [Portal]
Lancia, C., Anninga, J., Spitoni, C., Sydes, M. R., Whelan, J., Hogendoorn, P. C. W., Gelderblom, H., & Fiocco, M. (2019). Method to measure the mismatch between target and achieved received dose intensity of chemotherapy in cancer trials: A retrospective analysis of the MRC BO06 trial in osteosarcoma. BMJ Open, 9(5), Article e022980. [DOI] [Repository]
Lancia, C., Anninga, J. K., Sydes, M. R., Spitoni, C., Whelan, J., Hogendoorn, P. C. W., Gelderblom, H., & Fiocco, M. (2019). A novel method to address the association between received dose intensity and survival outcome: benefits of approaching treatment intensification at a more individualised level in a trial of the European Osteosarcoma Intergroup. Cancer Chemotherapy and Pharmacology, 83, 951-962. [DOI] [Repository]
van Enter, A. C. D., Kimura, B., Ruszel, W., & Spitoni, C. (2019). Nucleation for One-Dimensional Long-Range Ising Models. Journal of Statistical Physics, 174(6), 1327–1345. [DOI] [Repository]
Postma, D. F., Spitoni, C., van Werkhoven, C. H., van Elden, L. J. R., Oosterheert, J. J., & Bonten, M. J. M. (2019). Cardiac events after macrolides or fluoroquinolones in patients hospitalized for community-acquired pneumonia: post-hoc analysis of a cluster-randomized trial. BMC Infectious Diseases, 19, Article 17. [DOI] [Repository]
Lancia, C., & Spitoni, C. (2019). Marginal structural models with dose-delay joint-exposure for assessing variations to chemotherapy intensity. Statistical Methods in Medical Research, 28(9), 2787-2801. [DOI] [Repository]
2018
Scholarly publications
Kimura, B., Ruszel, W. M., & Spitoni, C. (2018). Ergodicity versus non-ergodicity for Probabilistic Cellular Automata on rooted trees. Markov Processes and Related Fields, 25(2), 189-216. [DOI] [Repository]
Cirillo, E. M. N., Nardi, F. R., & Spitoni, C. (2018). Basic Ideas to Approach Metastability in Probabilistic Cellular Automata. In Probabilistic Cellular Automata, Theory, Applications and Future Perspectives (pp. 37-51). (Emergence, Complexity and Computation; Vol. 27). Springer. [DOI] [Repository]
Frencken, J. F., Donker, D. W., Spitoni, C., Koster-Brouwer, M. E., Soliman, I. W., Ong, D. S. Y., Horn, J., van der Poll, T., van Klei, W. A., Bonten, M. J. M., & Cremer, O. L. (2018). Myocardial Injury in Patients With Sepsis and Its Association With Long-Term Outcome. Circulation. Cardiovascular quality and outcomes, 11(2), 1-9. Article e004040. [DOI] [Repository]
Frencken, J. F., Wittekamp, B. H. J., Plantinga, N. L., Spitoni, C., van de Groep, K., Cremer, O. L., & Bonten, M. J. M. (2018). Associations Between Enteral Colonization With Gram-Negative Bacteria and Intensive Care Unit-Acquired Infections and Colonization of the Respiratory Tract. Clinical Infectious Diseases, 66(4), 497–503. [DOI] [Repository]
Putter, H., & Spitoni, C. (2018). Non-parametric estimation of transition probabilities in non-markov multi-state model: The landmark Aalen-Johansen Estimator. Statistical Methods in Medical Research, 27(7), 2081–2092. [DOI] [Repository]
2017
Scholarly publications
Lancia, C., Spitoni, C., Anninga, J. K., Whelan, J., Sydes, M. R., Jovic, G., & Fiocco, M. (2017). Causal inference with randomised clinical trials of chemotherapy: The importance of well-documented treatment side-effects. Trials, 18(suppl 1), 214. Article 200. [DOI] [Repository]
Kimura, B., Ruszel, W. M., & Spitoni, C. (2017). Ergodicity versus non-ergodicity for Probabilistic Cellular Automata on rooted trees. arXiv.org. [Repository]
Cirillo, E. N. M., Nardi, F. R., & Spitoni, C. (2017). Sum of exit times in a series of two metastable states. European Physical Journal: Special Topics, 226(10), 2421-2438. [DOI] [Repository]
Ong, D. S. Y., Bonten, M. J. M., Spitoni, C., Lunel, F. M. V., Frencken, J. F., Horn, J., Schultz, M. J., van der Poll, T., Klouwenberg, P. M. C. K., & Cremer, O. L. (2017). Epidemiology of multiple herpes viremia in previously immunocompetent patients with septic shock. Clinical Infectious Diseases, 64(9), 1204–1210. [DOI] [Repository]
2016
Scholarly publications
Cirillo, E. N. M., Nardi, F. R., & Spitoni, C. (2016). Basic Ideas to Approach Metastability in Probabilistic Cellular Automata. arXiv. [Repository]
Anninga, J. K., Lancia, C., Spitoni, C., Gelderblom, H., & Fiocco, M. (2016). Causal effects of methotrexate reductions/delays in treatment of high-grade resectable osteosarcoma. Journal of Clinical Oncology, 34(15_suppl), Article e22502. [DOI]
van Mansfeld, R., de Vrankrijker, A., Brimicombe, R., Heijerman, H., Teding van Berkhout, F., Spitoni, C., Grave, S., van der Ent, C., Wolfs, T., Willems, R., & Bonten, M. (2016). The Effect of Strict Segregation on Pseudomonas aeruginosa in Cystic Fibrosis Patients. PLoS One, 11(6), 1-14. Article e0157189. [DOI] [Repository]
Cirillo, E. N. M., Nardi, F. R., & Spitoni, C. (2016). Sum of exit times in series of metastable states in Probabilistic Cellular Automata. Lecture Notes in Computer Science, 9664, 105-119. [DOI] [Repository]
van Vught, L. A., Klein Klouwenberg, P. M. C., Spitoni, C., Scicluna, B. P., Wiewel, M. A., Horn, J., Schultz, M. J., Nürnberg, P., Bonten, M. J. M., Cremer, O. L., van der Poll, T., & MARS Consortium (2016). Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis. JAMA - The Journal of The American Medical Association, 315(14), 1469-1479. [DOI] [Portal]
2015
Scholarly publications
Ong, D. S. Y., Bonten, M. J. M., Safdari, K., Spitoni, C., Frencken, J. F., Witteveen, E., Horn, J., Klein Klouwenberg, P. M. C., Cremer, O. L., & MARS Consortium (2015). Epidemiology, Management, and Risk-Adjusted Mortality of ICU-Acquired Enterococcal Bacteremia. Clinical Infectious Diseases. [DOI] [Repository]
Ong, D. S. Y., Spitoni, C., Klein Klouwenberg, P. M. C., Verduyn Lunel, F. M., Frencken, J. F., Schultz, M. J., van der Poll, T., Kesecioglu, J., Bonten, M. J. M., & Cremer, O. L. (2015). Cytomegalovirus reactivation and mortality in patients with acute respiratory distress syndrome. Intensive Care Medicine. [DOI] [Repository]
Ong, D. S. Y., Klein Klouwenberg, P. M. C., Verduyn Lunel, F. M., Frencken, J. F., Dekker, H. A. T., Schultz, M. J., Bonten, M. J. M., Spitoni, C., & Cremer, O. L. (2015). Cytomegalovirus Seroprevalence as a Risk Factor for Poor Outcome in Acute Respiratory Distress Syndrome. Critical Care Medicine, 43(2), 394-400. [DOI] [Portal]
2014
Scholarly publications
Ong, D. S. Y., Safdari, K., Klouwenberg, P. M. C. K., Spitoni, C., Frencken, J. F., Witteveen, E., Horn, J., Bonten, M. J. M., & Cremer, O. L. (2014). Epidemiology, management and clinical outcomes of ICU-acquired enterococcal bacteraemias. Critical Care, 1-53. [DOI]
Klouwenberg, P. M. C. K., Zaal, I. J., Ong, D. S. Y., Van Der Kooi, A. W., Bonten, M. J. M., Slooter, A. J. C., Cremer, O. L., & Spitoni, C. (2014). The attributable mortality of delirium in critically ill patients: Prospective cohort study. BMJ (International edition), 349, Article g6652. [DOI] [Repository]
Cirillo, E. N. M., Louis, P. Y., Ruszel, W. M., & Spitoni, C. (2014). Effect of self-interaction on the phase diagram of a Gibbs-like measure derived by a reversible Probabilistic Cellular Automata. Chaos, solitons & fractals, 64, 36-47. [DOI]
Other output
Ong, D., Spitoni, C., Klein Klouwenberg, P., Verduyn Lunel, F., Schultz, M., Bonten, M., & Cremer, O. (2014). Cytomegalovirus reactivation in critically ill patients with acute respiratory distress syndrome. Intensive Care Medicine, 40(1 supplement), S127. Article 0444. [DOI]
2013
Scholarly publications
Ong, D. S. Y., MC Klein Klouwenberg, P., Spitoni, C., Bonten, M. J. M., & Cremer, O. L. (2013). Nebulised amphotericin B to eradicate Candida colonisation from the respiratory tract in critically ill patients receiving selective digestive decontamination: A cohort study. Critical Care, 17(5), Article R233. [DOI]
Klouwenberg, P. K., Slooter, A., Spitoni, C., Ong, D., Bonten, M., Zaal, I., & Cremer, O. (2013). Attributable mortality of delirium in critically ill patients. Critical Care Medicine, 41(12), 150-151. [DOI]
2012
Scholarly publications
Nardi, F. R., & Spitoni, C. (2012). Sharp Asymptotics for Stochastic Dynamics with Parallel Updating Rule. Journal of Statistical Physics, 146(4), 701-718. [DOI]
Spitoni, C., Verduijn, M., & Putter, H. (2012). Estimation and Asymptotic Theory for Transition Probabilities in Markov Renewal Multi-State Models. International Journal of Biostatistics, 8(1), Article 1375. [DOI] [Repository]
Other output
Ong, D. S. Y., Klein Klouwenberg, P. M. C., Spitoni, C., Bonten, M. J. M., & Cremer, O. L. (2012). Effectiveness of nebulized amphotericin B to eradicate Candida colonization from the lower respiratory tracts of ICU patients.. Poster session presented at European Society of Intensive Care, Lissabon, Portugal.
2010
Scholarly publications
Cirillo, E. M. N., Nardi, F. R., & Spitoni, C. (2010). Competitive nucleation in metastable systems. [DOI]
Bovier, A., den Hollander, F., & Spitoni, C. (2010). HOMOGENEOUS NUCLEATION FOR GLAUBER AND KAWASAKI DYNAMICS IN LARGE VOLUMES AT LOW TEMPERATURES. Annals of Probability, 38(2), 661-713. [DOI]
2008
Scholarly publications
Cirillo, E. N. M., Nardi, F. R., & Spitoni, C. (2008). Metastability for reversible probabilistic cellular automata with self-interaction. Journal of Statistical Physics, 132(3), 431-471. [DOI]
Cirillo, E. N. M., Nardi, F. R., & Spitoni, C. (2008). Competitive nucleation in reversible probabilistic cellular automata. Physical review. E, 78(4). [DOI]
2005
Scholarly publications
Cavallaro, G., Marchioro, C., & Spitoni, C. (2005). Dynamics of Infinitely Many Particles Mutually Interacting in Three Dimensions via a Bounded Superstable Long-Range Potential. Journal of Statistical Physics, 120.