Publicaties
2023
Wetenschappelijke publicaties
Bhalla, D., Steijaert, M. N., Poppelaars, E. S., Teunis, M., van der Voet, M., Corradi, M., Dévière, E., Noothout, L., Tomassen, W., Rooseboom, M., Currie, R. A., Krul, C., Pieters, R., van Noort, V., & Wildwater, M. (2023). DARTpaths, an in silico platform to investigate molecular mechanisms of compounds. Bioinformatics, 39(1), 1-3. [btac767]. https://doi.org/10.1093/bioinformatics/btac767
2022
Wetenschappelijke publicaties
Corradi, M. P. F., de Haan, A. M., Staumont, B., Piersma, A. H., Geris, L., Pieters, R. H. H., Krul, C. A. M., & Teunis, M. A. T. (2022). Natural language processing in toxicology: Delineating adverse outcome pathways and guiding the application of new approach methodologies. Biomaterials and Biosystems, 7, [100061]. https://doi.org/10.1016/j.bbiosy.2022.100061
van den Berg, A. E. T., Plantinga, M., Vethaak, D., Adriaans, K. J., Bol-Schoenmakers, M., Legler, J., Smit, J. J., & Pieters, R. H. H. (2022). Environmentally weathered polystyrene particles induce phenotypical and functional maturation of human monocyte-derived dendritic cells. Journal of Immunotoxicology, 19(1), 125-133. https://doi.org/10.1080/1547691X.2022.2143968
Oost, M. J., Ijaz, A., van Haarlem, D. A., van Summeren, K., Velkers, F. C., Kraneveld, A. D., Venema, K., Jansen, C. A., Pieters, R. H. H., & Ten Klooster, J. P. (2022). Chicken-derived RSPO1 and WNT3 contribute to maintaining longevity of chicken intestinal organoid cultures. Scientific Reports, 12(1), 1-12. [10563]. https://doi.org/10.1038/s41598-022-14875-7
Lenssen, E. S., Pieters, R. H. H., Nijmeijer, S. M., Oldenwening, M., Meliefste, K., & Hoek, G. (2022). Short-term associations between barbecue fumes and respiratory health in young adults. Environmental Research, 204(Part A), [111868]. https://doi.org/10.1016/j.envres.2021.111868
2021
Wetenschappelijke publicaties
van der Voet, M., Teunis, M., Louter-van de Haar, J., Stigter, N., Bhalla, D., Rooseboom, M., Wever, K. E., Krul, C., Pieters, R., Wildwater, M., & van Noort, V. (2021). Towards a reporting guideline for developmental and reproductive toxicology testing in C. elegans and other nematodes. Toxicology Research, 10(6), 1202-1210. https://doi.org/10.1093/toxres/tfab109
Klooster, J. P. T., Bol-Schoenmakers, M., van Summeren, K., van Vliet, A. L. W., de Haan, C. A. M., van Kuppeveld, F. J. M., Verkoeijen, S., & Pieters, R. (2021). Enterocytes, fibroblasts and myeloid cells synergize in anti-bacterial and anti-viral pathways with IL22 as the central cytokine. Communications Biology, 4(1), 1-13. [631]. https://doi.org/10.1038/s42003-021-02176-0
Kuper, C. F., Pieters, R. H. H., & van Bilsen, J. H. M. (2021). Nanomaterials and the Serosal Immune System in the Thoracic and Peritoneal Cavities. International Journal of Molecular Sciences, 22(5), 1-15. [2610]. https://doi.org/10.3390/ijms22052610
2020
Wetenschappelijke publicaties
Kartaram, S. W., van Norren, K., Schoen, E., Teunis, M., Mensink, M., Verschuren, M., M'rabet, L., Besseling van der Vaart, I., Mohrmann, K., Wittink, H., Garssen, J., Witkamp, R. F., & Pieters, R. H. H. (2020). Kinetics of Physiological Responses as a Measure of Intensity and Hydration Status During Experimental Physical Stress in Human Volunteers. Frontiers in Physiology, 11(9), [1006]. https://doi.org/10.3389/fphys.2020.01006
Dekker, S. C., Kraneveld, A. D., van Dijk, J., Kalfagianni, A., Knulst, A. C., Lelieveldt, H., Moors, E. H. M., Müller, E., Pieters, R. H. H., Pieterse, C. M. J., Rosenkranz, S., Voesenek, L. A. C. J., & van Westen, A. C. M. (2020). Towards Healthy Planet Diets: A Transdisciplinary Approach to Food Sustainability Challenges. Global Challenges, 11(2), [21]. https://doi.org/10.3390/challe11020021
van Esch, B. C. A. M., van Bilsen, J. H. M., Gros- van Hest, M., Kleinjans, L., Belzer, C., Jeurink, P. V., Garssen, J., Smit, J. J., Pieters, R. H. H., & Knippels, L. M. J. (2020). A multi-center assessment to compare residual allergenicity of partial hydrolyzed whey proteins in a murine model for cow’s milk allergy – Comparison to the single parameter guinea pig model. Toxicology Letters, 333, 312-321. https://doi.org/10.1016/j.toxlet.2020.05.020
Giustarini, G., Huppelschoten, S., Barra, M., Oppelt, A., Wagenaar, L., Weaver, R. J., Bol-Schoenmakers, M., Smit, J. J., van de Water, B., Klingmüller, U., & Pieters, R. H. H. (2020). The hepatotoxic fluoroquinolone trovafloxacin disturbs TNF- and LPS-induced p65 nuclear translocation in vivo and in vitro. Toxicology and Applied Pharmacology, 391, [114915]. https://doi.org/10.1016/j.taap.2020.114915
Villemin, C., Tranquet, O., Solé-Jamault, V., Smit, J. J., Pieters, R. H. H., Denery-Papini, S., & Bouchaud, G. (2020). Deamidation and Enzymatic Hydrolysis of Gliadins Alter Their Processing by Dendritic Cells in Vitro. Journal of Agricultural and Food Chemistry, 68(5), 1447-1456. https://doi.org/10.1021/acs.jafc.9b06075, https://doi.org/10.1021/acs.jafc.9b06075
2019
Wetenschappelijke publicaties
Lozano-Ojalvo, D., Benedé, S., Antunes, C. M., Bavaro, S. L., Bouchaud, G., Costa, A., Denery-Papini, S., Díaz-Perales, A., Garrido-Arandia, M., Gavrovic-Jankulovic, M., Hayen, S., Martínez-Blanco, M., Molina, E., Monaci, L., Pieters, R. H. H., Villemin, C., Wichers, H. J., Wróblewska, B., Willemsen, L. E. M., ... van Bilsen, J. H. M. (2019). Applying the adverse outcome pathway (AOP) for food sensitization to support in vitro testing strategies. Trends in Food Science and Technology, 85, 307-319. https://doi.org/10.1016/j.tifs.2019.01.014
Nešić, A., Čavić, M., Popović, M., Zlatanova, M., Pieters, R., Smit, J., & Gavrović-Jankulović, M. (2019). The Kiwifruit Allergen Act d 1 Activates NF-κB Signaling and Affects mRNA Expression of TJ Proteins and Innate Pro-Allergenic Cytokines. Biomolecules, 9(12). https://doi.org/10.3390/biom9120816
Braber, S., Bol-Schoenmakers, M., Akbari, P., Jeurink, P. V., Graaff, P. D., Smit, J. J., Van Esch, B. C. A. M., Garssen, J., Fink-Gremmels, J., & Pieters, R. H. H. (2019). Allergic Sensitization to Whey in Mice Is Facilitated By the Mycotoxin Deoxynivalenol (DON). 75-76. Abstract from World allergy congress, Seoul, Korea, Republic of. https://doi.org/10.1186/s40413-016-0096-1
Weaver, R. J., Blomme, E. A., Chadwick, A. E., Copple, I. M., Gerets, H. H. J., Goldring, C. E., Guillouzo, A., Hewitt, P. G., Ingelman-Sundberg, M., Jensen, K. G., Juhila, S., Klingmüller, U., Labbe, G., Liguori, M. J., Lovatt, C. A., Morgan, P., Naisbitt, D. J., Pieters, R. H. H., Snoeys, J., ... Park, B. K. (2019). Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models. Nature Reviews. Drug Discovery. https://doi.org/10.1038/s41573-019-0048-x
Nešić, A., Stam, A., Čavić, M., Ten Klooster, J. P., Pieters, R., Smit, J., & Gavrović-Jankulović, M. (2019). Activation of epithelial cells by the major kiwifruit allergen Act d 1 in human and mouse-derived intestinal model. Journal of Functional Foods, 62, 103556. https://doi.org/10.1016/j.jff.2019.103556
Van Bilsen, J. H. M., Verschuren, L., Wagenaar, L., Vonk, M. M., Van Esch, B. C. A. M., Knippels, L. M. J., Garssen, J., Smit, J. J., Pieters, R. H. H., & Van Den Broek, T. J. (2019). A network-based approach for identifying suitable biomarkers for oral immunotherapy of food allergy. BMC Bioinformatics, 20(1), [206]. https://doi.org/10.1186/s12859-019-2802-9
Wagenaar, L., Van Roest, M., Kruijssen, L. J. W., Simons, P. J., Boon, L., Vonk, M. M., Van Esch, B. C. A. M., Knippels, L. M. J., Garssen, J., Pieters, R. H. H., & Smit, J. J. (2019). Non-digestible oligosaccharides scFOS/lcFOS facilitate safe subcutaneous immunotherapy for peanut allergy. Clinical and Molecular Allergy, 17(1), [7]. https://doi.org/10.1186/s12948-019-0111-5
Wagenaar, L., Bol-Schoenmakers, M. W. H. C., Giustarini, G., Garssen, J., Smit, J. J., & Pieters, R. H. H. (2019). Mouse strain differences in response to oral immunotherapy for peanut allergy. Immunity, inflammation and disease, 7(1), 41-51. https://doi.org/10.1002/iid3.242
Giustarini, G., Vrisekoop, N., Kruijssen, L., Wagenaar, L., Van Staveren, S., Van Roest, M., Bleumink, R., Bol-Schoenmakers, M., Weaver, R. J., Koenderman, L., Smit, J., & Pieters, R. (2019). Trovafloxacin-Induced Liver Injury: Lack in Regulation of Inflammation by Inhibition of Nucleotide Release and Neutrophil Movement. Toxicological Sciences, 167(2), 385-396. https://doi.org/10.1093/toxsci/kfy244
Vonk, M. M., Blokhuis, B. R. J., Diks, M. A. P., Wagenaar, L., Smit, J. J., Pieters, R. H. H., Garssen, J., Knippels, L. M. J., & van Esch, B. C. A. M. (2019). Butyrate Enhances Desensitization Induced by Oral Immunotherapy in Cow's Milk Allergic Mice. Mediators of Inflammation, 2019, [9062537]. https://doi.org/10.1155/2019/9062537
van der Kleij, H. P. M., Warmenhoven, H. J. M., van Ree, R., Versteeg, S. A., Pieters, R. H. H., Dreskin, S. C., Knulst, A. C., Hoffen, E. V., Opstelten, D. J. E., Koppelman, S. J., & Smit, J. J. (2019). Chemically modified peanut extract shows increased safety while maintaining immunogenicity. Allergy. https://doi.org/10.1111/all.13687
Kartaram, S., Mensink, M., Teunis, M., Schoen, E., Witte, G., Janssen Duijghuijsen, L., Verschuren, M., Mohrmann, K., M'Rabet, L., Knipping, K., Wittink, H., van Helvoort, A., Garssen, J., Witkamp, R., Pieters, R., & van Norren, K. (2019). Plasma citrulline concentration, a marker for intestinal functionality, reflects exercise intensity in healthy young men. Clinical Nutrition, 38(5), 2251-2258. https://doi.org/10.1016/j.clnu.2018.09.029
2018
Wetenschappelijke publicaties
Koppelman, S. J., Smits, M., Tomassen, M., de Jong, G. A. H., Baumert, J., Taylor, S. L., Witkamp, R., Veldman, R. J., Pieters, R., & Wichers, H. (2018). Release of Major Peanut Allergens from Their Matrix under Various pH and Simulated Saliva Conditions-Ara h2 and Ara h6 Are Readily Bio-Accessible. Nutrients, 10(9), [E1281]. https://doi.org/10.3390/nu10091281
Ten Klooster, J. P., Sotiriou, A., Boeren, S., Vaessen, S., Vervoort, J., & Pieters, R. (2018). Type 2 diabetes-related proteins derived from an in vitro model of inflamed fat tissue. Archives of Biochemistry and Biophysics, 644, 81-92. https://doi.org/10.1016/j.abb.2018.03.003
Villeneuve, D. L., Landesmann, B., Allavena, P., Ashley, N., Bal-Price, A., Corsini, E., Halappanavar, S., Hussell, T., Laskin, D., Lawrence, T., Nikolic-Paterson, D., Pallardy, M., Paini, A., Pieters, R., Roth, R., & Tschudi-Monnet, F. (2018). Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways. Toxicological Sciences, 163(2), 346-352. https://doi.org/10.1093/toxsci/kfy047
Wagenaar, L., Bol-Schoenmakers, M., Giustarini, G., Vonk, M. M., van Esch, B. C. A. M., Knippels, L. M. J., Garssen, J., Smit, J. J., & Pieters, R. H. H. (2018). Dietary Supplementation with Non-Digestible Oligosaccharides Reduces Allergic Symptoms and Supports Low Dose Oral Immunotherapy in a Peanut Allergy Mouse Model. Molecular Nutrition & Food Research, 62(20), [1800369]. https://doi.org/10.1002/mnfr.201800369
Perusko, M., van Roest, M., Stanic-Vucinic, D., Simons, P. J., Pieters, R., Velickovic, T. C., & Smit, J. J. (2018). Glycation of the Major Milk Allergen β-Lactoglobulin Changes its Allergenicity by Alterations in Cellular Uptake and Degradation. Molecular Nutrition & Food Research, 62(17), [e1800341]. https://doi.org/10.1002/mnfr.201800341
Giustarini, G., Kruijssen, L., van Roest, M., Bleumink, R., Weaver, R. J., Bol-Schoenmakers, M., Smit, J., & Pieters, R. (2018). Tissue influx of neutrophils and monocytes is delayed during development of trovafloxacin-induced tumor necrosis factor-dependent liver injury in mice. Journal of applied toxicology, 38(5), 753-765. https://doi.org/10.1002/jat.3585
2017
Wetenschappelijke publicaties
Racz, P. I., Wildwater, M., Rooseboom, M., Kerkhof, E., Pieters, R., Yebra-Pimentel, E. S., Dirks, R. P., Spaink, H. P., Smulders, C., & Whale, G. F. (2017). Application of Caenorhabditis elegans (nematode) and Danio rerio embryo (zebrafish) as model systems to screen for developmental and reproductive toxicity of Piperazine compounds. Toxicology in Vitro, 44, 11-16. https://doi.org/10.1016/j.tiv.2017.06.002
Hammerschmidt-Kamper, C., Biljes, D., Merches, K., Steiner, I., Daldrup, T., Bol-Schoenmakers, M., Pieters, R. H. H., & Esser, C. (2017). Indole-3-carbinol, a plant nutrient and AhR-Ligand precursor, supports oral tolerance against OVA and improves peanut allergy symptoms in mice. PLoS One, 12(6), 1-17. [e0180321]. https://doi.org/10.1371/journal.pone.0180321
Vonk, M. M., Diks, M. A. P., Wagenaar, L., Smit, J. J., Pieters, R. H. H., Garssen, J., van Esch, B. C. A. M., & Knippels, L. M. J. (2017). Improved Efficacy of Oral Immunotherapy Using Non-Digestible Oligosaccharides in a Murine Cow's Milk Allergy Model: A Potential Role for Foxp3+Regulatory T Cells. Frontiers in Immunology, 8, [1230]. https://doi.org/10.3389/fimmu.2017.01230
Vonk, M. M., Wagenaar, L., Pieters, R. H. H., Knippels, L. M. J., Willemsen, L. E. M., Smit, J. J., van Esch, B. C. A. M., & Garssen, J. (2017). The efficacy of oral and subcutaneous antigen-specific immunotherapy in murine cow's milk- and peanut allergy models. Clinical and Translational Allergy, 7(1), [35]. https://doi.org/10.1186/s13601-017-0170-y, https://doi.org/10.1186/s13601-017-0170-y
van Bilsen, J. H. M., Sienkiewicz-Szłapka, E., Lozano-Ojalvo, D., Willemsen, L. E. M., Antunes, C. M., Molina, E., Smit, J. J., Wróblewska, B., Wichers, H. J., Knol, E. F., Ladics, G. S., Pieters, R. H. H., Denery-Papini, S., Vissers, Y. M., Bavaro, S. L., Larré, C., Verhoeckx, K. C. M., & Roggen, E. L. (2017). Application of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteins. Clinical and Translational Allergy, 7(1), 13. https://doi.org/10.1186/s13601-017-0152-0
Vaessen, S. F. C., van Lipzig, M. M. H., Pieters, R. H. H., Krul, C. A. M., Wortelboer, H. M., & van de Steeg, E. (2017). Regional expression levels of drug transporters and metabolizing enzymes along the pig and human intestinal tract and comparison with Caco-2 cells. Drug Metabolism and Disposition, 45(4), 353-360. https://doi.org/10.1124/dmd.116.072231
JanssenDuijghuijsen, L. M., Keijer, J., Mensink, M., Lenaerts, K., Ridder, L., Nierkens, S., Kartaram, S. W., Verschuren, M. C. M., Pieters, R. H. H., Bas, R., Witkamp, R. F., Wichers, H. J., & van Norren, K. (2017). Adaptation of exercise-induced stress in well-trained healthy young men. Experimental Physiology, 102(1), 86-99. https://doi.org/10.1113/EP086025
Overige resultaten
Wagenaar, L., Vonk, M. M., Giustarini, G., Bol-Schoenmakers, M. W., Van Esch, B. C., Knippels, L. M., Garssen, J., Pieters, R. H., & Smit, J. J. (2017). Reducing allergic symptoms with oral immunotherapy supported by a non-digestible oligosaccharide supplemented diet in a peanut allergy mouse model. 724. https://doi.org/10.1111/all.13252
2016
Wetenschappelijke publicaties
Wagenaar, L., Vonk, M. M., Van Roest, M., Kruijssen, L. J. W., Van Esch, B. C. A. M., Knippels, L. M. J., Garssen, J., Pieters, R. H. H., & Smit, J. J. (2016). Oral immunotherapy in combination with a non-digestible oligosaccharide supplemented diet in a peanut allergy mouse model. Allergy: European Journal of Allergy and Clinical Immunology, 71, 167. https://doi.org/10.1111/all.12972
Te Velde, A. A., Bezema, T., van Kampen, A. H. C., Kraneveld, A. D., 't Hart, B. A., van Middendorp, H., Hack, E. C., van Montfrans, J. M., Belzer, C., Jans-Beken, L., Pieters, R. H., Knipping, K., Huber, M., Boots, A. M. H., Garssen, J., Radstake, T. R., Evers, A. W. M., Prakken, B. J., & Joosten, I. (2016). Embracing Complexity beyond Systems Medicine: A New Approach to Chronic Immune Disorders. Frontiers in Immunology, 7, [587]. https://doi.org/10.3389/fimmu.2016.00587
Kwast, L., Aida, T., Fiechter, D., Kruijssen, L., Bleumink, R., Boon, L., Ludwig, I., & Pieters, R. (2016). Immune responses induced by diclofenac or carbamazepine in an oral exposure model using TNP-Ficoll as reporter antigen. Journal of Immunotoxicology, 13(6), 918-926. https://doi.org/10.1080/1547691X.2016.1247929
Vonk, M. M., Wagenaar, L., Smit, J. J., Pieters, R. H. H., Willemsen, L. E. M., Garssen, J., Van Esch, B. C. A. M., & Knippels, L. M. J. (2016). The combination of oral immunotherapy and a non-digestible oligosaccharide supplemented diet reduced allergic symptoms in a murine cow's milk allergy model. Allergy: European Journal of Allergy and Clinical Immunology, 71, 251. https://doi.org/10.1111/all.12972
van der Wielen, N., Ten Klooster, J. P., Muckenschnabl, S., Pieters, R., Hendriks, H. F., Witkamp, R. F., & Meijerink, J. (2016). The Noncaloric Sweetener Rebaudioside A Stimulates Glucagon-Like Peptide 1 Release and Increases Enteroendocrine Cell Numbers in 2-Dimensional Mouse Organoids Derived from Different Locations of the Intestine. Journal of Nutrition, 146(12), 2429-35. https://doi.org/10.3945/jn.116.232678
Poland, M., Ten Klooster, J. P., Wang, Z., Pieters, R., Boekschoten, M., Witkamp, R., & Meijerink, J. (2016). Docosahexaenoyl serotonin, an endogenously formed n-3 fatty acid-serotonin conjugate has anti-inflammatory properties by attenuating IL-23-IL-17 signaling in macrophages. Biochimica et Biophysica Acta, 1861(12 Part A), 2020-2028. https://doi.org/10.1016/j.bbalip.2016.09.012
Bøgh, K. L., van Bilsen, J., Głogowski, R., López-Expósito, I., Bouchaud, G., Blanchard, C., Bodinier, M., Smit, J., Pieters, R., Bastiaan-Net, S., de Wit, N., Untersmayr, E., Adel-Patient, K., Knippels, L., Epstein, M. M., Noti, M., Nygaard, U. C., Kimber, I., Verhoeckx, K., & O'Mahony, L. (2016). Current challenges facing the assessment of the allergenic capacity of food allergens in animal models. Clinical and Translational Allergy, 6, [21]. https://doi.org/10.1186/s13601-016-0110-2
Kwast, L., Fiechter, D., Kruijssen, L., Bleumink, R., Ludwig, I., Bol-Schoenmakers, M., Smit, J., & Pieters, R. (2016). Oral exposure to immunostimulating drugs results in early changes in innate immune parameters in the spleen. Journal of Immunotoxicology, 13(4), 535-47. https://doi.org/10.3109/1547691X.2016.1139643
Knipping, K., van Roest, M., Kruijssen, L., Smits, M., Teunis, M., Cox, L., de Jong, N., Simons, P. J., Boon, L., Teshima, R., Gros, M., Kegler, D., Garssen, J., Knippels, L. M. J., & Pieters, R. (2016). Intra- and inter-laboratory validation of an innovative huFcεRIα-RBL-2H3 degranulation assay for in vitro allergenicity assessment of whey hydrolysates. Toxicology in Vitro, 33, 317-324. https://doi.org/10.1016/j.tiv.2016.02.018
Bol-Schoenmakers, M., Braber, S., Akbari, P., de Graaff, P., van Roest, M., Kruijssen, L., Smit, J. J., van Esch, B. C. A. M., Jeurink, P. V., Garssen, J., Fink-Gremmels, J., & Pieters, R. H. H. (2016). The mycotoxin deoxynivalenol facilitates allergic sensitization to whey in mice. Mucosal Immunology. https://doi.org/10.1038/mi.2016.13
2015
Wetenschappelijke publicaties
Vonk, M. M., Wagenaar, L., Diks, M. A. P., Hofman, G. A., Dingjan, G. M., Smit, J. J., Pieters, R. H. H., Willemsen, L. E. M., Garssen, J., Knippels, L. M. J., & Van Esch, B. C. A. M. (2015). Comparing oral and subcutaneous antigen-specific immunotherapy in a cow's milk allergy mouse model. 200. http://www.embase.com/search/results?subaction=viewrecord&from=export&id=L72029063
Wagenaar, L., Vonk, M. M., Van Roest, M., Kruijssen, L. J. W., Knippels, L. M. J., Van Esch, B. C. A. M., Pieters, R. H. H., & Smit, J. J. (2015). Oral and subcutaneous immunotherapy in a peanut allergy mouse model. In Allergy: European Journal of Allergy and Clinical Immunology (pp. 200). (Allergy: European Journal of Allergy and Clinical Immunology; Vol. 70). http://www.embase.com/search/results?subaction=viewrecord&from=export&id=L72029062
Jayasena, S., Smits, M., Fiechter, D., de Jong, A., Nordlee, J., Baumert, J., Taylor, S. L., Pieters, R. H., & Koppelman, S. J. (2015). Comparison of six commercial ELISA kits for their specificity and sensitivity in detecting different major peanut allergens. Journal of Agricultural and Food Chemistry, 63(6), 1849-55. https://doi.org/10.1021/jf504741t
Smit, J. J., Pennings, M. T., Willemsen, K., van Roest, M., van Hoffen, E., & Pieters, R. H. (2015). Heterogeneous responses and cross reactivity between the major peanut allergens Ara h 1, 2,3 and 6 in a mouse model for peanut allergy. Clinical and Translational Allergy, 5(13). https://doi.org/10.1186/s13601-015-0056-9
Overige resultaten
Vonk, M. M., Wagenaar, L., Diks, M. A. P., Hofman, G. A., Dingjan, G. M., Smit, J. J., Pieters, R. H. H., Willemsen, L. E. M., Garssen, J., Knippels, L. M. J., & Van Esch, B. C. A. M. (2015). Comparing oral and subcutaneous antigen-specific immunotherapy in a cow's milk allergy mouse model. 200. https://doi.org/10.1111/all.12717
Bol-Schoenmakers, M., Braber, S., Akbari, P., Jeurink, P., De Graaff, P., Smit, J. J., Van Esch, B., Garssen, J., Fink-Gremmels, J., & Pieters, R. H. H. (2015). The mycotoxin deoxynivalenol (DON) facilitates allergic sensitization to whey in mice. Allergy, 70, 17. https://doi.org/10.1111/all.12715
2014
Wetenschappelijke publicaties
Van Esch, B. C. A. M., Van Bilsen, J. H. M., Van Gros-Hest, M., Jeurink, P. V., Garssen, J., Smit, J. J., Pieters, R. H. H., & Knippels, L. M. J. (2014). Allergenicity assessment of hydrolysed infant formulas; Comparison of a guinea pig and a mouse model for cow's milk allergy. Allergy, 69, 267. https://doi.org/10.1111/all.12476
Stojadinovic, M., Pieters, R., Smit, J., & Velickovic, T. C. (2014). Cross-linking of β-lactoglobulin enhances allergic sensitization through changes in cellular uptake and processing. Toxicological Sciences, 140(1), 224-35. https://doi.org/10.1093/toxsci/kfu062
van den Elsen, L. W., Bol-Schoenmakers, M., van Esch, B. C., Hofman, G. A., van de Heijning, B. J., Pieters, R. H., Smit, J. J., Garssen, J., & Willemsen, L. E. (2014). DHA-Rich Tuna Oil Effectively Suppresses Allergic Symptoms in Mice Allergic to Whey or Peanut. Journal of Nutrition, 144(12), 1970-6. https://doi.org/10.3945/jn.114.198515
Teunis, M. A. T., Spiekstra, S. W., Smits, M., Adriaens, E., Eltze, T., Galbiati, V., Krul, C., Landsiedel, R., Pieters, R., Reinders, J., Roggen, E., Corsini, E., & Gibbs, S. (2014). International ring trial of the epidermal equivalent sensitizer potency assay: reproducibility and predictive-capacity. Altex, 31(3), 251-68. https://doi.org/10.14573/altex.1308021
Steenhof, M., Janssen, N. A. H., Strak, M., Hoek, G., Gosens, I., Mudway, I. S., Kelly, F. J., Harrison, R. M., Pieters, R. H. H., Cassee, F. R., & Brunekreef, B. (2014). Air pollution exposure affects circulating white blood cell counts in healthy subjects: the role of particle composition, oxidative potential and gaseous pollutants - the RAPTES project. Inhalation Toxicology, 26(3), 141-165. https://doi.org/10.3109/08958378.2013.861884
2013
Wetenschappelijke publicaties
Van Esch, B. C. A. M., Van Bilsen, J. H. M., Jeurink, P. V., Garssen, J., Verhoeckx, K. C. M., Smit, J. J., Pieters, R. H. H., & Knippels, L. M. J. (2013). Multicenter validation of a mouse model for cow's milk allergy to assess the allergenicity of hydrolysed cow's milk based infant formulae. Clinical and Translational Allergy, 3.
Steenhof, M., Mudway, I. S., Gosens, I., Hoek, G., Godri, K. J., Kelly, F. J., Harrison, R. M., Pieters, R. H. H., Cassee, F. R., Lebret, E., Brunekreef, B. A., Strak, M., & Janssen, N. A. H. (2013). Acute nasal pro-inflammatory response to air pollution depends on characteristics other than particle mass concentration or oxidative potential: the RAPTES project. Occupational and Environmental Medicine, 70(5), 341-8. https://doi.org/10.1136/oemed-2012-100993
van Esch, E. C. A. M., van Bilsen, J. H. M., Jeurink, P., Penninks, A. H., Smit, J. J., Pieters, R. H. H., Knippels, L. M., & Garssen, J. (2013). Interlaboratory evaluation of a cow's milk allergy mouse model to assess the allergenicity of hydrolysed cow's milk based infant formulas. Toxicology Letters, 220(1), 95-102. https://doi.org/10.1016/j.toxlet.2013.04.008
Kimber, I., & Pieters, R. (2013). Household chemicals, immune function, and allergy: A commentary. Journal of Immunotoxicology, 10(2), 169-172. https://doi.org/10.3109/1547691X.2012.707696
Teunis, M., Corsini, E., Smits, M., Madsen, C., Eltze, T., Ezendam, J., Galbiati, V., Gremmer, E., Krul, C., Landin, A., Landsiedel, R., Pieters, R., Rasmussen, T. F., Reinders, J., Roggen, E., Spiekstra, S., & Gibbs, S. (2013). Transfer of a two-tiered keratinocyte assay: IL-18 production by NCTC2544 to determine the skin sensitizing capacity and epidermal equivalent assay to determine sensitizer potency. Toxicology in Vitro, 27(3), 1135-1150. https://doi.org/10.1016/j.tiv.2012.06.004
Schulz, V. J., van Roest, M., Bol-Schoenmakers, M., van Duursen, M. B. M., van den Berg, M., Pieters, R. H. H., & Smit, J. J. (2013). Aryl hydrocarbon receptor activation affects the dendritic cell phenotype and function during allergic sensitization. Immunobiology, 218(8), 1055-1062. https://doi.org/10.1016/j.imbio.2013.01.004
Overige resultaten
van Esch, E. C. A. M., van Bilsen, J., van Gros-Hest, M., Jeurink, P. V., Garssen, J., Smit, J. J., Pieters, R. H. H., & Knippels, L. M. (2013). Multicenter validation of a mouse model for cow's milk allergy to assess the allergenicity of hydrolysed cow's milk based infant formulas; phase III. 321-322. Poster session presented at Special Issue: Abstracts from the European Academy of Allergy and Clinical Immunology and World Allergy Organization World Allergy and Asthma.
2012
Wetenschappelijke publicaties
Schulz, V. J., Smit, J. J., Huijgen, V. C., Bol-Schoenmakers, M., van Roest, M., Kruijssen, L. W. J., Fiechter, D., Hassing, I., Bleumink, A. R. J., Safe, S., van Duursen, M. B. M., van den Berg, M., & Pieters, R. H. H. (2012). Non-dioxin-like AhR ligands in a mouse peanut allergy model. Toxicological Sciences, 128(1), 92-102. https://doi.org/10.1093/toxsci/kfs131
2011
Wetenschappelijke publicaties
Bol-Schoenmakers, M., Bleumink, R., Marcondes Rezende, M., Mouser, E., Hassing, I., Ludwig, I. S., Smit, J. J., & Pieters, R. H. H. (2011). Diclofenac enhances allergic responses in a mouse peanut allergy model. Clinical and Experimental Allergy, 41(3), 424-433. https://doi.org/10.1111/j.1365-2222.2010.03594.x
Kwast, L. M., Fiechter, D., Hassing, I., Bleumink, R., Boon, L., Ludwig, I. S., & Pieters, R. H. H. (2011). Oral exposure to drugs with immune-adjuvant potential induces hypersensitivity responses to the reporter antigen TNP-OVA. Toxicological Sciences, 121(2), 312-319. https://doi.org/10.1093/toxsci/kfr052
Smit, J. J., Bol-Schoenmakers, M., Hassing, I., Fiechter, D., Boon, L., Bleumink, R., & Pieters, R. (2011). The role of intestinal dendritic cells subsets in the establishment of food allergy. Clinical and Experimental Allergy, 41(6), 890-898. https://doi.org/10.1111/j.1365-2222.2011.03738.x
Bezemer, G. F. G., Bauer, S. M., Oberdörster, G., Breysse, P. N., & Pieters, R. H. H. (2011). Activation of pulmonary dendritic cells and Th2-type inflammatory responses on instillation of engineered, environmental diesel emission source or ambient air pollutant particles in vivo. Journal of Innate Immunity, 3(2), 150-166. https://doi.org/10.1159/000321725
Marcondes Rezende, M., Hassing, I., Bol-Schoenmakers, M., Bleumink, R., Boon, L., van Bilsen, J., & Pieters, R. (2011). CD4(+) CD25(+) T regulatory cells do not transfer oral tolerance to peanut allergens in a mouse model of peanut allergy. Clinical and Experimental Allergy, 41(9), 1324-1333. https://doi.org/10.1111/j.1365-2222.2010.03662.x
Ahlem, C. N., Auci, D. L., Nicoletti, F., Pieters, R., Kennedy, M., Page, T. M., Reading, C. L., Enioutina, E. Y., & Frincke, J. (2011). Pharmacology and immune modulating properties of 5-androstene-3β,7β,17β-triol, a DHEA metabolite in the human metabolome. Journal of Steroid Biochemistry and Molecular Biology, 126(3-5), 87-94. https://doi.org/10.1016/j.jsbmb.2011.04.010
Corsini, E., Oukka, M., Pieters, R., Kerkvliet, N. I., Ponce, R., & Germolec, D. (2011). Alterations in regulatory T-cells: Rediscovered pathways in immunotoxicology. Journal of Immunotoxicology, 8(4), 251-257. https://doi.org/10.3109/1547691X.2011.598885
Smit, J. J., Willemsen, K., Hassing, I., Fiechter, D., Storm, G., van Bloois, L., Leusen, J. H. W., Pennings, M., Zaiss, D. M. W., & Pieters, R. H. H. (2011). Contribution of classic and alternative effector pathways in peanut-induced anaphylactic responses. PLoS One, 6(12), 10.1371/journal.pone.0028917. https://doi.org/10.1371/journal.pone.0028917
Schulz, V. J., Smit, J. J., Willemsen, K. J., Fiechter, D., Hassing, I., Bleumink, R., Boon, L., van den Berg, M., van Duursen, M. B. M., & Pieters, R. H. H. (2011). Activation of the aryl hydrocarbon receptor suppresses sensitization in a mouse peanut allergy model. Toxicological Sciences, 123(2), 491-500. https://doi.org/10.1093/toxsci/kfr175
2010
Wetenschappelijke publicaties
Ludwig, I. S., Kwast, L. M., Fiechter, D., & Pieters, R. H. H. (2010). An in vivo tiered approach to test immunosensitization by low molecular weight compounds. Methods in Molecular Biology, 598(Part 2), 27-37. https://doi.org/10.1007/978-1-60761-401-2_3
Conrad, D., Wang, A., Pieters, R., Nicoletti, F., Mangano, K., van Heeckeren, A., White, S. K., Frincke, J., Reading, C. L., Stickney, D., & Auci, D. L. (2010). HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression. Journal of Inflammation (BioMed Central), 7, [7:52]. https://doi.org/10.1186/1476-9255-7-52
Fecek, R., Marcondes Rezende, M., Busche, R., Hassing, I., Pieters, R., & Cuff, C. F. (2010). Enteric reovirus infection stimulates peanut-specific IgG2a responses in a mouse food allergy model. Immunobiology, 215(12), 941-948. https://doi.org/10.1016/j.imbio.2010.02.004
Carfi', M., Bowe, G., Ferrario, D., Pieters, R., & Gribaldo, L. (2010). Maintenance and characterization of lymphocytes in human long term bone marrow cultures to study immunotoxicity. Toxicology in Vitro, 24(5), 1395-1403. https://doi.org/10.1016/j.tiv.2010.04.014
2009
Wetenschappelijke publicaties
Nicoletti, F., Conrad, D., Wang, A., Pieters, R., Mangano, K., van Heeckeren, A., White, S. K., Frincke, J., Reading, C. L., Auci, D. L., & Stickney, D. (2009). 16alpha-Bromoepiandrosterone (HE2000) limits non-productive inflammation and stimulates immunity in lungs. Clinical and Experimental Immunology, 158(3), 308-316. https://doi.org/10.1111/j.1365-2249.2009.04032.x
2008
Wetenschappelijke publicaties
Carfi', M., Croera, C., Ferrario, D., Campi, V., Bowe, G., Pieters, R. H. H., & Gribaldo, L. (2008). TBTC induces adipocyte differentiation in human bone marrow long term culture. Toxicology, 249(1), 11-18.
de Haar, C., Kool, M., Hassing, I., Bol-Schoenmakers, M., Lambrecht, B. N., & Pieters, R. H. H. (2008). Lung dendritic cells are stimulated by ultrafine particles and play a key role in particle adjuvant activity. Journal of Allergy and Clinical Immunology, 121(5), 1246-1254.
2007
Wetenschappelijke publicaties
van Wijk, F., Wehrens, E. J. M., Nierkens, S., Boon, L., Kasran, A., Pieters, R., & Knippels, L. M. (2007). CD4+CD25+ T cells regulate the intensity of hypersensitivity responses to peanut, but are not decisive in the induction of oral sensitization. Clinical and Experimental Allergy, 37(4), 572-581.
Carfi', M., Gennari, A., Malerba, I., Corsini, E., Pallardy, M., Pieters, R., van Loveren, H., Vohr, H. W., Hartung, T., & Gribaldo, L. (2007). In vitro tests to evaluate immunotoxicity: a preliminary study. Toxicology, 229(1-2), 11-22.
van Wijk, F., Nierkens, S., de Jong, W., Wehrens, E. J. M., Boon, L., van Kooten, P., Knippels, L. M., & Pieters, R. (2007). The CD28/CTLA-4-B7`signaling pathway is involved in both allergic sensitization and tolerance induction to orally administered peanut proteins. Journal of Immunology, 178(11), 6894-900.
Pieters, R. H. H. (2007). Detection of autoimmunity by pharmaceuticals. Methods, 41(1), 112-117.
2006
Wetenschappelijke publicaties
de Haar, C. G., Hassing, I., Bol, M. W. H. C., Bleumink, R., & Pieters, R. H. H. (2006). Ultrafine but not fine particulate matter causes airway inflammation and allergic airway sensitization to co-administered antigen in mice. Clinical and Experimental Allergy, 36(11), 1469-1479.
2005
Wetenschappelijke publicaties
Nierkens, S., Aalbers, M., Bol, M. W. H. C., van Wijk, F., Hassing, G. A. M., & Pieters, R. H. H. (2005). Development of an oral exposure mouse model to predict drug-induced hypersensitivity reactions by using reporter antigens. Toxicological Sciences, 83, 273-281.
Ezendam, J., Kosterman, K., Spijkerboer, H., Bleumink, A. R. J., Hassing, G. A. M., van Rooijen, N., Vos, J. G., & Pieters, R. H. H. (2005). Macrophages are involved in hexachlorobenzene-induced adverse immune effects. Toxicology and Applied Pharmacology, 209, 19-27.
Nygaard, U. C., Alberg, T., Bleumink, A. R. J., Aase, A., Dybing, E., Pieters, R., & Lovik, M. (2005). Ambient air particles from four European cities increase the primary cellular response to allergen in the draining lymph node. Toxicology, 207, 241-254.
van Wijk, F., Nierkens, S., Hassing, G. A. M., Feijen, M., Koppelman, S. J., Jong, G. A. H., Pieters, R. H. H., & Knippels, L. M. (2005). The effect of the food matrix on in vivo immune responses to purified peanut allergens. Toxicological Sciences, 86(2), 333-341.
Ezendam, J., Vos, J. G., & Pieters, R. H. H. (2005). Mechanisms of hexachlorobenzene-induced adverse effects in brown norway rats. Journal of Immunology, 1, 167-175.
Nierkens, S., Aalbers, M., Bol, M. W. H. C., Bleumink, A. R. J., van Kooten, P. J., Boon, L., & Pieters, R. H. H. (2005). Differential requirement for CD28/CTLA-4-CD80/CD86 interactions in drug-induced type 1 and type 2 immune response tot trinitrophenyl-ovalbumin. Journal of Immunology, 175, 3707-3714.
Nierkens, S., Bleumink, A. R. J., Bol-Schoenmakers, M., Hassing, G. A. M., van Rooijen, N., & Pieters, R. H. H. (2005). The reactive D-glucopyranose moiety of streptozotocin is responsible for activation of macrophages and subsequent stimulation of CD8+ T cells. Chemical Research in Toxicology, 18, 872-879.
2004
Wetenschappelijke publicaties
Ezendam, J., Vos, J. G., & Pieters, R. (2004). Letter to the editor: Toxicological Sciences. Toxicological Sciences, 81, 254-255.
Ezendam, J., Hassing, G. A. M., Bleumink, A. R. J., Vos, J. G., & Pieters, R. H. H. (2004). Hexachlorobenzene-induced immunopathology in brown Norway rats is partly mediated by T cells. Toxicological Sciences, 78, 88-95.
2003
Wetenschappelijke publicaties
Albers, R., Bol-Schoenmakers, M., Bleumink, A. R. J., Willems, A. A., & Pieters, R. H. H. (2003). Effects of supplementation with vitamins A, C, and E, selenium, and zinc on immune function in a murine sensitization model. Nutrition, 19, 940-946.
Ezendam, J., Vissers, I., Bleumink, R., Vos, J. G., & Pieters, R. H. H. (2003). Immunomodulatory effects of tetrachlorobenzoquinone, a reactive metabolite of hexachlorobenzene. Chemical Research in Toxicology, 16, 688-694.
2002
Wetenschappelijke publicaties
Gennari, A., Bol, M. W. H. C., Seinen, W., Penninks, A., & Pieters, R. (2002). Organotin-induced apoptosis occurs in small CD4(+)CD8(+) thymocytes and is accompanied by an increase in RNA synthesis. Toxicology, 175, 191-200.
Albers, R., Bol, M. W. H. C., Bleumink, R., Willems, A., Blonck, C., & Pieters, R. (2002). Effects of dietary lipids on immune function in a murine sensitisation model. British Journal of Nutrition, 88, 291-299.
Nierkens, S., van Helden, P., Bol, M. W. H. C., Bleumink, R., van Kooten, P., Ramdien-Murli, S., Boon, L., & Pieters, R. (2002). Selective requirement for CD40-CD154 in drug-induced type 1 versus type 2 responses to trinitrophenyl-ovalbumin. Journal of Immunology, 168(8), 3747-3754.
Gennari, A., Bleumink, R., Viviani, B., Galli, C. L., Marinovich, M., Pieters, R., & Corsini, E. (2002). Identification by DNA macroarray of nur77 as a gene induced by di-n-butyltin dichloride: its role in organotin-induced apoptosis. Toxicology and Applied Pharmacology, 181, 27-31.
Eisenbrand, G., Pool-Zobel, B., Baker, V., Balls, M., Blaauboer, B. J., Boobis, A., Carere, A., Kevekordes, S., Lhuguenot, J. C., Pieters, R., & Kleiner, J. (2002). Methods of in vitro toxicology. Food and Chemical Toxicology, 40, 193-236.
2001
Wetenschappelijke publicaties
Pieters, R. (2001). The popliteal lymph node assay: a tool for predicting drug allergies. Toxicology, 158, 65-69.
2000
Wetenschappelijke publicaties
van Zijverden, M., van der Pijl, A., Bol, M. W. H. C., van Pinxteren, F. A., de Haar, C. G., Penninks, A. H., van Loveren, H., & Pieters, R. (2000). Diesel exhaust, carbon black, and silica particles display distinct Th1/Th2 modulating activity. Toxicology and Applied Pharmacology, 168, 131-139.
Pieters, R. (2000). The popliteal lymph node assay in predictive testing for autoimmunity. Toxicology Letters, 112, 453-459.
Vakpublicaties
Nierkens, S., van Helden, P. M. W., Bleumink, A. R. J., van Kooten, P. J., Boon, L., & Pieters, R. H. H. (2000). The role of CD40-CD40L interaction in Th1- and Th2-like immunostimulation caused by pharmaceuticals. Immunobiology, 203, 573-574.