Prof. dr. H.C. (Hendrik) Korswagen

Hoogleraar
Developmental Biology
h.c.korswagen@uu.nl

Publicaties

2021

Wetenschappelijke publicaties

Rella, L., Fernandes Póvoa, E. E., Mars, J., Ebbing, A. L. P., Schoppink, L., Betist, M. C., & Korswagen, H. C. (2021). A switch from noncanonical to canonical Wnt signaling stops neuroblast migration through a Slt-Robo and RGA-9b/ARHGAP-dependent mechanism. Proceedings of the National Academy of Sciences of the United States of America, 118(12), 1-12. [e2013239118]. https://doi.org/10.1073/pnas.2013239118
Rödelsperger, C., Ebbing, A., Sharma, D. R., Okumura, M., Sommer, R. J., Korswagen, H. C., & Ruvinsky, I. (Ed.) (2021). Spatial Transcriptomics of Nematodes Identifies Sperm Cells as a Source of Genomic Novelty and Rapid Evolution. Molecular Biology and Evolution, 38(1), 229–243. https://doi.org/10.1093/molbev/msaa207

2020

Wetenschappelijke publicaties

Fernandes Póvoa, E. E., Ebbing, A. L. P., Betist, M. C., Van Der Veen, C., & Korswagen, H. C. (2020). An optimized dissociation protocol for FACS-based isolation of rare cell types from Caenorhabditis elegans L1 larvae. MethodsX, 7, [100922]. https://doi.org/10.1016/j.mex.2020.100922
Gupta, S., Fancher, S., Korswagen, H. C., & Mugler, A. (2020). Temporal precision of molecular events with regulation and feedback. Physical Review E, 101(6), [062420 ]. https://doi.org/10.1103/PhysRevE.101.062420

2018

Wetenschappelijke publicaties

Gupta, S., Varennes, J., Korswagen, H. C., Mugler, A., & Bennett, M. R. (Ed.) (2018). Temporal precision of regulated gene expression. PLoS Computational Biology, 14(6), [e1006201]. https://doi.org/10.1371/journal.pcbi.1006201
Mcgough, I. J., De Groot, R. E. A., Jellett, A. P., Betist, M. C., Varandas, K. C., Danson, C. M., Heesom, K. J., Korswagen, H. C., & Cullen, P. J. (2018). SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion. Nature Communications, 9(1), [3737]. https://doi.org/10.1038/s41467-018-06114-3
Ebbing, A., Vértesy, Á., Betist, M. C., Spanjaard, B., Junker, J. P., Berezikov, E., Van Oudenaarden, A., & Korswagen, H. C. (2018). Spatial Transcriptomics of C. elegans Males and Hermaphrodites Identifies Sex-Specific Differences in Gene Expression Patterns. Developmental Cell, 47(6), 801-813.e6. https://doi.org/10.1016/j.devcel.2018.10.016
Mentink, R. A., Rella, L., Radaszkiewicz, T. W., Gybel, T., Betist, M. C., Bryja, V., Korswagen, H. C., & Chisholm, A. D. (2018). The planar cell polarity protein VANG-1/Vangl negatively regulates Wnt/β-catenin signaling through a Dvl dependent mechanism. PLoS Genetics, 14(12), [e1007840]. https://doi.org/10.1371/journal.pgen.1007840
Doitsidou, M., Minevich, G., Kroll, J. R., Soete, G., Gowtham, S., Korswagen, H. C., Sebastiaan van Zon, J., & Hobert, O. (2018). A Caenorhabditis elegans Zinc Finger Transcription Factor, ztf-6, Required for the Specification of a Dopamine Neuron-Producing Lineage. G3: Genes, Genomes, Genetics, 8(1), 17-26. https://doi.org/10.1534/g3.117.300132

2014

Wetenschappelijke publicaties

Lorenowicz, M. J., Macurkova, M., Harterink, M., de Groot, R., & Korswagen, H. (2014). Inhibition of late endosomal maturation restores Wnt secretion in Caenorhabditis elegans vps-29 retromer mutants. Cellular Signalling, 26(1), 19-31. https://doi.org/10.1016/j.cellsig.2013.09.013

2013

Wetenschappelijke publicaties

de Groot, R. E. A., Farin, H. F., Macurkova, M., Clevers, H. C., & Korswagen, H. C. (2013). Retromer dependent recycling of the Wnt secretion factor Wls is dispensable for stem cell maintenance in the mammalian intestinal epithelium. PLoS One, 8(10), e76971. [e76971].
Ji, N., Middelkoop, T. C., Mentink, R. A., Tonegawa, S., Korswagen, H. C., & van Oudenaarden, A. (2013). Feedback control of gene expression variability in the Caenorhabditis elegans Wnt pathway. Cell, 155(4), 869-80.
Putker, M., Madl, T., Vos, H. R., de Ruiter, H., Visscher, M., van den Berg, M. C. W., Kaplan, M., Korswagen, H. C., Boelens, R., Vermeulen, M., Burgering, B. M. T., & Dansen, T. B. (2013). Redox-dependent control of FOXO/DAF-16 by transportin-1. Molecular Cell, 49(4), 730-742. https://doi.org/10.1016/j.molcel.2012.12.014
Cruciat, C. M., Dolde, C., de Groot, R. E. A., Ohkawara, B., Reinhard, C., Korswagen, H. C., & Niehrs, C. (2013). RNA helicase DDX3 is a regulatory subunit of casein kinase 1 in Wnt-beta-catenin signaling. Science, 339(6126), 1436-41.
Tan, R. Z., Ji, N., Mentink, R. A., Korswagen, H. C., & van Oudenaarden, A. (2013). Deconvolving the roles of Wnt ligands and receptors in sensing and amplification. Molecular Systems Biology [E], 9, 631. [631].
Labuschagne, C. F., Stigter, E. C. A., Hendriks, M. M. W. B., Berger, R., Rokach, J., Korswagen, H. C., & Brenkman, A. B. (2013). Quantification of in vivo oxidative damage in Caenorhabditis elegans during aging by endogenous F3-isoprostane measurement. Aging Cell, 12(2), 214-23.
Stout, G. J., Stigter, E. C. A., Essers, P. B. M., Mulder, K. W., Kolkman, A., Snijders, D. S., van de Broek, N. J., Korswagen, H. C., & Brenkman, A. B. (2013). Insulin/IGF-1-mediated longevity is marked by reduced protein metabolism. Molecular Systems Biology [E], 9, 679. [679].

2008

Wetenschappelijke publicaties

Neumann, S., Coudreuse, D., van der Westhuyzen, D. R., Eckhardt, E. R. M., Korswagen, H. C., Schmitz, G., & Sprong, H. (2008). Mammalian Wnt3a is released on lipoprotein particles. Traffic, in press.
https://dspace.library.uu.nl/bitstream/handle/1874/33221/11.%2520Neumann%25202008%2520pp.pdf?sequence=1

2000

Wetenschappelijke publicaties

Korswagen, H. C., Herman, M., & Clevers, H. C. (2000). Distinct beta-catenins mediate adhesion and signalling functions in C. elegans. Nature, 406, 527-532.

1997

Wetenschappelijke publicaties

Jonkers, J., Korswagen, H. C., Acton, D. S., Breuer, M., & Berns, A. (1997). Activation of a novel proto-oncogene Frat-1, contributes to progression of mouse T-cell lymphomas. EMBO Journal, 60, 441-450.