2020

  • Ye S, Boeter JWB, Mihajlovic M, van Steenbeek FG, van Wolferen ME, Oosterhoff LA, et al. A Chemically Defined Hydrogel for Human Liver Organoid Culture. Advanced Functional Materials. 2020;30(48).
  • Wong CW, Metselaar JM, Storm G, Wong TT. A review of the clinical applications of drug delivery systems for the treatment of ocular anterior segment inflammation. British Journal of Ophthalmology. 2020.
  • Wong CW, Busoy JMF, Cheung N, Barathi VA, Storm G, Wong TT. Endogenous or exogenous retinal pigment epithelial cells: A comparison of two experimental animal models of proliferative vitreoretinopathy. Translational Vision Science and Technology. 2020;9(9):1-10.
  • Wellens LM, Deken MM, Sier CFM, Johnson HR, de la Jara Ortiz F, Bhairosingh SS, et al. Anti-GD2-IRDye800CW as a targeted probe for fluorescence-guided surgery in neuroblastoma. Scientific Reports. 2020;10(1).
  • Wei Y, Gu X, Sun Y, Meng F, Storm G, Zhong Z. Transferrin-binding peptide functionalized polymersomes mediate targeted doxorubicin delivery to colorectal cancer in vivo. Journal of Controlled Release. 2020;319:407-15.
  • Wang Y, van Steenbergen MJ, Beztsinna N, Shi Y, Lammers T, van Nostrum CF, et al. Biotin-decorated all-HPMA polymeric micelles for paclitaxel delivery. Journal of Controlled Release. 2020;328:970-84.
  • Wander P, Cheung LC, Pinhanҫos SS, Jones L, Kerstjens M, Arentsen-Peters STCJM, et al. Preclinical efficacy of gemcitabine in MLL-rearranged infant acute lymphoblastic leukemia. Leukemia. 2020;34(11):2898-902.
  • Varela-Moreira A, van Straten D, van Leur HF, Ruiter RWJ, Deshantri AK, Hennink WE, et al. Polymeric micelles loaded with carfilzomib increase tolerability in a humanized bone marrow-like scaffold mouse model. International Journal of Pharmaceutics: X. 2020;2.
  • Van Ravensteijn BGP, Voets IK, Kegel WK, Eelkema R. Out-of-Equilibrium Colloidal Assembly Driven by Chemical Reaction Networks. Langmuir. 2020;36(36):10639-56.
  • van Ravensteijn BGP, Hage PA, Voets IK. Framed by depletion. Nature Materials. 2020;19(12):1261-3.
  • van Raath MI, Chohan S, Wolkerstorfer A, van der Horst CMAM, Limpens J, Huang X, et al. Clinical outcome measures and scoring systems used in prospective studies of port wine stains: A systematic review. PLoS ONE. 2020;15(7 July).
  • van Gelder MK, Jong JAW, Folkertsma L, Guo Y, Blüchel C, Verhaar MC, et al. Urea removal strategies for dialysate regeneration in a wearable artificial kidney. Biomaterials. 2020;234.
  • van der Weide H, Cossío U, Gracia R, te Welscher YM, ten Kate MT, van der Meijden A, et al. Therapeutic efficacy of novel antimicrobial peptide AA139-nanomedicines in a multidrug-resistant klebsiella pneumoniae pneumonia-septicemia model in rats. Antimicrobial Agents and Chemotherapy. 2020;64(9).
  • Tryfonidou MA, de Vries G, Hennink WE, Creemers LB. “Old Drugs, New Tricks” – Local controlled drug release systems for treatment of degenerative joint disease. Advanced Drug Delivery Reviews. 2020;160:170-85.
  • ten Hove M, Pater L, Storm G, Weiskirchen S, Weiskirchen R, Lammers T, et al. The hepatic lipidome: From basic science to clinical translation. Advanced Drug Delivery Reviews. 2020;159:180-97.
  • Tas ML, Nagtegaal M, Kraal KCJM, Tytgat GAM, Abeling NGGM, Koster J, et al. Neuroblastoma stage 4S: Tumor regression rate and risk factors of progressive disease. Pediatric Blood and Cancer. 2020;67(4).
  • Sun Q, Bai X, Sofias AM, van der Meel R, Ruiz-Hernandez E, Storm G, et al. Cancer nanomedicine meets immunotherapy: opportunities and challenges. Acta Pharmacologica Sinica. 2020;41(7):954-8.
  • Shi H, van Steenbergen MJ, Lou B, Liu Y, Hennink WE, Kok RJ. Folate decorated polymeric micelles for targeted delivery of the kinase inhibitor dactolisib to cancer cells. International Journal of Pharmaceutics. 2020;582.
  • Sheybanifard M, Beztsinna N, Bagheri M, Buhl EM, Bresseleers J, Varela-Moreira A, et al. Systematic evaluation of design features enables efficient selection of Π electron-stabilized polymeric micelles. International Journal of Pharmaceutics. 2020;584.
  • Setaro F, Wennink JWH, Mäkinen PI, Holappa L, Trohopoulos PN, Ylä-Herttuala S, et al. Amphiphilic phthalocyanines in polymeric micelles: A supramolecular approach toward efficient third-generation photosensitizers. Journal of Materials Chemistry B. 2020;8(2):282-9.
  • Schubert NA, Lowery CD, Bergthold G, Koster J, Eleveld TF, Rodríguez A, et al. Systematic target actionability reviews of preclinical proof-of-concept papers to match targeted drugs to paediatric cancers. European Journal of Cancer. 2020;130:168-81.
  • Schilder IPA, Veening-Griffioen DH, Ferreira GS, Van Meer PJK, Gispen-De Wied CC, Schellekens H, et al. Pathways in the drug development for Alzheimer's disease (1906-2016): A bibliometric study. Journal of Scientometric Research. 2020;9(3):277-92.
  • Scheiner KC, Coulter F, Maas-Bakker RF, Ghersi G, Nguyen TT, Steendam R, et al. Vascular Endothelial Growth Factor–Releasing Microspheres Based on Poly(ε-Caprolactone-PEG-ε-Caprolactone)-b-Poly(L-Lactide) Multiblock Copolymers Incorporated in a Three-Dimensional Printed Poly(Dimethylsiloxane) Cell Macroencapsulation Device. Journal of Pharmaceutical Sciences. 2020;109(1):863-70.
  • Ritter D, Knebel J, Niehof M, Loinaz I, Marradi M, Gracia R, et al. In vitro inhalation cytotoxicity testing of therapeutic nanosystems for pulmonary infection. Toxicology in Vitro. 2020;63.
  • Rendina A, Drongitis D, Donizetti A, Fucci L, Milan G, Tripodi F, et al. CD33 and SIGLECL1 immunoglobulin superfamily involved in dementia. Journal of Neuropathology and Experimental Neurology. 2020;79(8):890-901.
  • Qiu B, Bessler N, Figler K, Buchholz MB, Rios AC, Malda J, et al. Bioprinting Neural Systems to Model Central Nervous System Diseases. Advanced Functional Materials. 2020;30(44).
  • Priwitaningrum DL, Jentsch J, Bansal R, Rahimian S, Storm G, Hennink WE, et al. Apoptosis-inducing peptide loaded in PLGA nanoparticles induces anti-tumor effects in vivo. International Journal of Pharmaceutics. 2020;585.
  • Poon E, Liang T, Jamin Y, Walz S, Kwok C, Hakkert A, et al. Orally bioavailable CDK9/2 inhibitor shows mechanism-based therapeutic potential in MYCN-driven neuroblastoma. Journal of Clinical Investigation. 2020;130(11):5875-92.
  • Piluso S, Flores Gomez D, Dokter I, Moreira Texeira L, Li Y, Leijten J, et al. Rapid and cytocompatible cell-laden silk hydrogel formation: Via riboflavin-mediated crosslinking. Journal of Materials Chemistry B. 2020;8(41):9566-75.
  • Patras L, Fens MHAM, Vader P, Barendrecht A, Sesarman A, Banciu M, et al. Normoxic tumour extracellular vesicles modulate the response of hypoxic cancer and stromal cells to doxorubicin in vitro. International Journal of Molecular Sciences. 2020;21(17):1-21.
  • Pascale E, Divisato G, Palladino R, Auriemma M, Ngalya EF, Caiazzo M. Noncoding rnas and midbrain da neurons: Novel molecular mechanisms and therapeutic targets in health and disease. Biomolecules. 2020;10(9):1-21.
  • Oude Blenke E, Mahakena S, Fens M, van den Dikkenberg J, Holkers M, Mastrobattista E. Impact of chemistry and nanoformulation parameters on cellular uptake and airway distribution of RNA oligonucleotides. Journal of Controlled Release. 2020;317:154-65.
  • Ou YH, Zou S, Goh WJ, Chong SY, Venkatesan G, Wacker MG, et al. Micro cell vesicle technology (mCVT): A novel hybrid system of gene delivery for hard-to-transfect (HTT) cells. Nanoscale. 2020;12(35):18022-30.
  • Nkanga CI, Fisch A, Rad-Malekshahi M, Romic MD, Kittel B, Ullrich T, et al. Clinically established biodegradable long acting injectables: An industry perspective. Advanced Drug Delivery Reviews. 2020;167:19-46.
  • Nijen Twilhaar MK, Czentner L, Grabowska J, Affandi AJ, Lau CYJ, Olesek K, et al. Optimization of liposomes for antigen targeting to splenic cd169+ macrophages. Pharmaceutics. 2020;12(12):1-21.
  • Najafi M, Asadi H, Van Den Dikkenberg J, Van Steenbergen MJ, Fens MHAM, Hennink WE, et al. Conversion of an Injectable MMP-Degradable Hydrogel into Core-Cross-Linked Micelles. Biomacromolecules. 2020;21(5):1739-51.
  • Moss JI, Barjat H, Emmas SA, Strittmatter N, Maynard J, Goodwin RJA, et al. High-resolution 3D visualization of nanomedicine distribution in tumors. Theranostics. 2020;10(2):880-97.
  • Moreno L, Barone G, DuBois SG, Molenaar J, Fischer M, Schulte J, et al. Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma. European Journal of Cancer. 2020;136:52-68.
  • Metz B, Michiels T, Uittenbogaard J, Danial M, Tilstra W, Meiring HD, et al. Identification of Formaldehyde-Induced Modifications in Diphtheria Toxin. Journal of Pharmaceutical Sciences. 2020;109(1):543-57.
  • May JN, Golombek SK, Baues M, Dasgupta A, Drude N, Rix A, et al. Multimodal and multiscale optical imaging of nanomedicine delivery across the blood-brain barrier upon sonopermeation. Theranostics. 2020;10(4):1948-59.
  • Mashayekhi V, Xenaki KT, van Bergen en Henegouwen PMP, Oliveira S. Dual targeting of endothelial and cancer cells potentiates in vitro nanobody-targeted photodynamic therapy. Cancers. 2020;12(10):1-18.
  • Mashayekhi V, Hoog CO, Oliveira S. Vascular targeted photodynamic therapy: A review of the efforts towards molecular targeting of tumor vasculature. Porphyrin Science By Women (In 3 Volumes). 2020:175-86.
  • Martínez-Jothar L, Barendrecht AD, de Graaff AM, Oliveira S, van Nostrum CF, Schiffelers RM, et al. Endothelial cell targeting by crgd-functionalized polymeric nanoparticles under static and flow conditions. Nanomaterials. 2020;10(7):1-19.
  • Mardhian DF, Vrynas A, Storm G, Bansal R, Prakash J. FGF2 engineered SPIONs attenuate tumor stroma and potentiate the effect of chemotherapy in 3D heterospheroidal model of pancreatic tumor. Nanotheranostics. 2020;4(1):26-39.
  • Manzella G, Schreck LD, Breunis WB, Molenaar J, Merks H, Barr FG, et al. Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity. Nature Communications. 2020;11(1).
  • Lobatto ME, Binderup T, Robson PM, Giesen LFP, Calcagno C, Witjes J, et al. Multimodal Positron Emission Tomography Imaging to Quantify Uptake of 89Zr-Labeled Liposomes in the Atherosclerotic Vessel Wall. Bioconjugate Chemistry. 2020;31(2):360-8.
  • Liu Y, Van Steenbergen MJ, Zhong Z, Oliveira S, Hennink WE, Van Nostrum CF. Dithiolane-Crosslinked Poly(ϵ-caprolactone)-Based Micelles: Impact of Monomer Sequence, Nature of Monomer, and Reducing Agent on the Dynamic Crosslinking Properties. Macromolecules. 2020;53(16):7009-24.
  • Liu Y, Scrivano L, Peterson JD, Fens MHAM, Hernández IB, Mesquita B, et al. EGFR-Targeted Nanobody Functionalized Polymeric Micelles Loaded with mTHPC for Selective Photodynamic Therapy. Molecular Pharmaceutics. 2020;17(4):1276-92.
  • Liu Y, Fens MHAM, Lou B, van Kronenburg NCH, Maas-Bakker RFM, Kok RJ, et al. π-π-stacked poly(ε-caprolactone)-b-poly(ethylene glycol) micelles loaded with a photosensitizer for photodynamic therapy. Pharmaceutics. 2020;12(4).
  • Liu Y, Fens MHAM, Capomaccio RB, Mehn D, Scrivano L, Kok RJ, et al. Correlation between in vitro stability and pharmacokinetics of poly(ε-caprolactone)-based micelles loaded with a photosensitizer. Journal of Controlled Release. 2020;328:942-51.
  • Li M, Ingmar van Raath M, Khakpour S, Seçilir A, Sliggers BC, Huang X, et al. In vivo assessment of thermosensitive liposomes for the treatment of port wine stains by antifibrinolytic site-specific pharmaco-laser therapy. Pharmaceutics. 2020;12(6):1-27.
  • Lau CYJ, Fontana F, Mandemaker LDB, Wezendonk D, Vermeer B, Bonvin AMJJ, et al. Control over the fibrillization yield by varying the oligomeric nucleation propensities of self-assembling peptides. Communications Chemistry. 2020;3(1).
  • Lau CYJ, Fontana F, Mandemaker LDB, Wezendonk D, Vermeer B, Bonvin AMJJ, et al. Author Correction: Control over the fibrillization yield by varying the oligomeric nucleation propensities of self-assembling peptides (Communications Chemistry, (2020), 3, 1, (164), 10.1038/s42004-020-00417-7). Communications Chemistry. 2020;3(1).
  • Lammers T, Sofias AM, van der Meel R, Schiffelers R, Storm G, Tacke F, et al. Dexamethasone nanomedicines for COVID-19. Nature Nanotechnology. 2020;15(8):622-4.
  • Kurniawan DW, Storm G, Prakash J, Bansal R. Role of spleen tyrosine kinase in liver diseases. World Journal of Gastroenterology. 2020;26(10):1005-19.
  • Kurniawan DW, Booijink R, Pater L, Wols I, Vrynas A, Storm G, et al. Fibroblast growth factor 2 conjugated superparamagnetic iron oxide nanoparticles (FGF2-SPIONs) ameliorate hepatic stellate cells activation in vitro and acute liver injury in vivo. Journal of Controlled Release. 2020;328:640-52.
  • Kloos R, van der Sluis IM, Mastrobattista E, Hennink W, Pieters R, Verhoef JJ. Acute lymphoblastic leukaemia patients treated with PEGasparaginase develop antibodies to PEG and the succinate linker. British Journal of Haematology. 2020;189(3):442-51.
  • Jong JAW, Guo Y, Veenhoven C, Moret ME, Van Der Zwan J, Lucini Paioni A, et al. Phenylglyoxaldehyde-Functionalized Polymeric Sorbents for Urea Removal from Aqueous Solutions. ACS Applied Polymer Materials. 2020;2(2):515-27.
  • Jong JAW, Guo Y, Hazenbrink D, Douka S, Verdijk D, van der Zwan J, et al. A Ninhydrin-Type Urea Sorbent for the Development of a Wearable Artificial Kidney. Macromolecular Bioscience. 2020;20(3).
  • Jahanmard F, Dijkmans FM, Majed A, Vogely HC, Van Der Wal BCH, Stapels DAC, et al. Toward Antibacterial Coatings for Personalized Implants. ACS Biomaterials Science and Engineering. 2020;6(10):5486-92.
  • Jahanmard F, Croes M, Castilho M, Majed A, Steenbergen MJ, Lietaert K, et al. Bactericidal coating to prevent early and delayed implant-related infections. Journal of Controlled Release. 2020;326:38-52.
  • Ilochonwu BC, Urtti A, Hennink WE, Vermonden T. Intravitreal hydrogels for sustained release of therapeutic proteins. Journal of Controlled Release. 2020;326:419-41.
  • Hernández IB, Angelier ML, D’ondes TDB, Di Maggio A, Yu Y, Oliveira S. The potential of nanobody-targeted photodynamic therapy to trigger immune responses. Cancers. 2020;12(4).
  • Guo Y, van Ravensteijn BGP, Kegel WK. Self-assembly of isotropic colloids into colloidal strings, Bernal spiral-like, and tubular clusters. Chemical Communications. 2020;56(46):6309-12.
  • Gong J, Schuurmans CCL, Genderen AM, Cao X, Li W, Cheng F, et al. Complexation-induced resolution enhancement of 3D-printed hydrogel constructs. Nature Communications. 2020;11(1).
  • George SL, Lorenzi F, King D, Hartlieb S, Campbell J, Pemberton H, et al. Therapeutic vulnerabilities in the DNA damage response for the treatment of ATRX mutant neuroblastoma. EBioMedicine. 2020;59.
  • Fliervoet LAL, Zhang H, van Groesen E, Fortuin K, Duin NJCB, Remaut K, et al. Local release of siRNA using polyplex-loaded thermosensitive hydrogels. Nanoscale. 2020;12(18):10347-60.
  • Ferreira GS, Veening-Griffioen DH, Boon WPC, Hooijmans CR, Moors EHM, Schellekens H, et al. Comparison of drug efficacy in two animal models of type 2 diabetes: A systematic review and meta-analysis. European Journal of Pharmacology. 2020;879.
  • Elsharkasy OM, Nordin JZ, Hagey DW, de Jong OG, Schiffelers RM, Andaloussi SE, et al. Extracellular vesicles as drug delivery systems: Why and how? Advanced Drug Delivery Reviews. 2020;159:332-43.
  • Doevendans E, Schellekens H. Protein Quality Testing in the Era of Personalized Medicine. Journal of Pharmaceutical Sciences. 2020;109(10):2962-8.
  • Diloksumpan P, De Ruijter M, Castilho M, Gbureck U, Vermonden T, Van Weeren PR, et al. Combining multi-scale 3D printing technologies to engineer reinforced hydrogel-ceramic interfaces. Biofabrication. 2020;12(2).
  • Della Valle F, Thimma MP, Caiazzo M, Pulcrano S, Celii M, Adroub SA, et al. Transdifferentiation of Mouse Embryonic Fibroblasts into Dopaminergic Neurons Reactivates LINE-1 Repetitive Elements. Stem Cell Reports. 2020;14(1):60-74.
  • Deken MM, Kijanka MM, Beltrán Hernández I, Slooter MD, de Bruijn HS, van Diest PJ, et al. Nanobody-targeted photodynamic therapy induces significant tumor regression of trastuzumab-resistant HER2-positive breast cancer, after a single treatment session. Journal of Controlled Release. 2020;323:269-81.
  • de Jong OG, Murphy DE, Mäger I, Willms E, Garcia-Guerra A, Gitz-Francois JJ, et al. A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA. Nature Communications. 2020;11(1).
  • de Jong OG, Murphy DE, Mäger I, Willms E, Garcia-Guerra A, Gitz-Francois JJ, et al. Publisher Correction: A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA (Nature Communications, (2020), 11, 1, (1113), 10.1038/s41467-020-14977-8). Nature Communications. 2020;11(1).
  • de Bruijn HS, Mashayekhi V, Schreurs TJL, van Driel PBAA, Strijkers GJ, van Diest PJ, et al. Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging. Theranostics. 2020;10(5):2436-52.
  • Crommelin DJA, van Hoogevest P, Storm G. The role of liposomes in clinical nanomedicine development. What now? Now what? Journal of Controlled Release. 2020;318:256-63.
  • Crommelin DJA, Mastrobattista E, Hawe A, Hoogendoorn KH, Jiskoot W. Shifting Paradigms Revisited: Biotechnology and the Pharmaceutical Sciences. Journal of Pharmaceutical Sciences. 2020;109(1):30-43.
  • Croes M, Akhavan B, Sharifahmadian O, Fan H, Mertens R, Tan RP, et al. A multifaceted biomimetic interface to improve the longevity of orthopedic implants. Acta Biomaterialia. 2020;110:266-79.
  • Calandrini C, Schutgens F, Oka R, Margaritis T, Candelli T, Mathijsen L, et al. An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity. Nature Communications. 2020;11(1).
  • Bresseleers J, Bagheri M, Lebleu C, Lecommandoux S, Sandre O, Pijpers IAB, et al. Tuning size and morphology of mpeg-b-p(Hpma-bz) copolymer self-assemblies using microfluidics. Polymers. 2020;12(11):1-18.
  • Biancacci I, Sun Q, Möckel D, Gremse F, Rosenhain S, Kiessling F, et al. Optical imaging of the whole-body to cellular biodistribution of clinical-stage PEG-b-pHPMA-based core-crosslinked polymeric micelles. Journal of Controlled Release. 2020;328:805-16.
  • Besse HC, Chen Y, Scheeren HW, Metselaar JM, Lammers T, Moonen CTW, et al. A doxorubicin-glucuronide prodrug released from nanogels activated by high-intensity focused ultrasound liberated β-glucuronidase. Pharmaceutics. 2020;12(6):1-12.
  • Beltrán Hernández I, Rompen R, Rossin R, Xenaki KT, Katrukha EA, Nicolay K, et al. Correction to: Imaging of Tumor Spheroids, Dual-Isotope SPECT, and Autoradiographic Analysis to Assess the Tumor Uptake and Distribution of Different Nanobodies (Molecular Imaging and Biology, (2019), 21, 6, (1079-1088), 10.1007/s11307-019-01320-x). Molecular Imaging and Biology. 2020;22(1):217.
  • Arranja AG, Hennink WE, Chassagne C, Denkova AG, Nijsen JFW. Preparation and characterization of inorganic radioactive holmium-166 microspheres for internal radionuclide therapy. Materials Science and Engineering C. 2020;106.
  • Amin Yavari S, Croes M, Akhavan B, Jahanmard F, Eigenhuis CC, Dadbakhsh S, et al. Layer by layer coating for bio-functionalization of additively manufactured meta-biomaterials. Additive Manufacturing. 2020;32.
  • Aldosari MH, Hartog MD, Ganizada H, Evers MJW, Mastrobattista E, Schellekens H. Feasibility study for bedside production of recombinant human acid α-glucosidase: Technical and financial considerations. Current Pharmaceutical Biotechnology. 2020;21(6):467-79.
  • Affandi AJ, Grabowska J, Olesek K, Venegas ML, Barbaria A, Rodríguez E, et al. Selective tumor antigen vaccine delivery to human CD169+ antigen-presenting cells using ganglioside-liposomes. Proceedings of the National Academy of Sciences of the United States of America. 2020;117(44):27528-39.