2019

  • Zou Y, Wei Y, Sun Y, Bao J, Yao F, Li Z, et al. Cyclic RGD-functionalized and disulfide-crosslinked iodine-rich polymersomes as a robust and smart theranostic agent for targeted CT imaging and chemotherapy of tumor. Theranostics. 2019;9(26):8061-72.
  • Wong CW, Cheung N, Ho C, Barathi V, Storm G, Wong TT. Characterisation of the inflammatory cytokine and growth factor profile in a rabbit model of proliferative vitreoretinopathy. Scientific Reports. 2019;9(1).
  • Willems L, Van Westerveld L, Roberts S, Weitzhandler I, Calcines Cruz C, Hernandez-Garcia A, et al. Nature of amorphous hydrophilic block affects self-assembly of an artificial viral coat polypeptide. Biomacromolecules. 2019;20(10):3641-7.
  • Willems L, Roberts S, Weitzhandler I, Chilkoti A, Mastrobattista E, Van Der Oost J, et al. Inducible Fibril Formation of Silk-Elastin Diblocks. ACS Omega. 2019;4(5):9135-43.
  • Wilbie D, Walther J, Mastrobattista E. Delivery Aspects of CRISPR/Cas for in Vivo Genome Editing. Accounts of Chemical Research. 2019;52(6):1555-64.
  • Wei Y, Gu X, Cheng L, Meng F, Storm G, Zhong Z. Low-toxicity transferrin-guided polymersomal doxorubicin for potent chemotherapy of orthotopic hepatocellular carcinoma in vivo. Acta Biomaterialia. 2019;92:196-204.
  • Vlieger JSD, Crommelin DJ, Flühmann B, Klebovich I, Mühlebach S, Shah VP. A progress report on the 3rd international symposium on scientific and regulatory advances in biological and non-biological complex drugs: a to z in bioequivalence. GaBI Journal. 2019;8(3):128-31.
  • Veening-Griffioen DH, Ferreira GS, van Meer PJK, Boon WPC, Gispen-de Wied CC, Moors EHM, et al. Are some animal models more equal than others? A case study on the translational value of animal models of efficacy for Alzheimer's disease. European Journal of Pharmacology. 2019;859.
  • Van Ravensteijn BGP, Bou Zerdan R, Seo D, Cadirov N, Watanabe T, Gerbec JA, et al. Triple Function Lubricant Additives Based on Organic-Inorganic Hybrid Star Polymers: Friction Reduction, Wear Protection, and Viscosity Modification. ACS Applied Materials and Interfaces. 2019;11(1):1363-75.
  • Van Ravensteijn BGP, Bou Zerdan R, Helgeson ME, Hawker CJ. Minimizing Star-Star Coupling in Cu(0)-Mediated Controlled Radical Polymerizations. Macromolecules. 2019;52(2):601-9.
  • van Raath MI, Chohan S, Wolkerstorfer A, van der Horst CMAM, Storm G, Heger M. Port wine stain treatment outcomes have not improved over the past three decades. Journal of the European Academy of Dermatology and Venereology. 2019;33(7):1369-77.
  • van Moorsel MVA, Urbanus RT, Verhoef S, Koekman CA, Vink M, Vermonden T, et al. A head-to-head comparison of conjugation methods for VHHs: Random maleimide-thiol coupling versus controlled click chemistry. International Journal of Pharmaceutics: X. 2019;1.
  • van Hilst J, Brinkman DJ, de Rooij T, van Dieren S, Gerhards MF, de Hingh IH, et al. The inflammatory response after laparoscopic and open pancreatoduodenectomy and the association with complications in a multicenter randomized controlled trial. HPB. 2019;21(11):1453-61.
  • van Golen RF, Reiniers MJ, Marsman G, Alles LK, van Rooyen DM, Petri B, et al. The damage-associated molecular pattern HMGB1 is released early after clinical hepatic ischemia/reperfusion. Biochimica et Biophysica Acta - Molecular Basis of Disease. 2019;1865(6):1192-200.
  • Sun RF, Vromans H, Hennink WE, Van Hasselt PM, Van Nostrum CF. View on effective oral alternative for newborns with cholestasis: Improved formulations for vitamin K prophylaxis. Pharmaceutisch Weekblad. 2019;154(21):14-5.
  • Sun Q, Barz M, De Geest BG, Diken M, Hennink WE, Kiessling F, et al. Nanomedicine and macroscale materials in immuno-oncology. Chemical Society Reviews. 2019;48(1):351-81.
  • Shi H, Lou B, van Steenbergen MJ, Sijbrandi NJ, Hennink WE, Kok RJ. Polymeric Micelles Employing Platinum(II) Linker for the Delivery of the Kinase Inhibitor Dactolisib. Particle and Particle Systems Characterization. 2019;36(8).
  • Shi H, Leonhard WN, Sijbrandi NJ, van Steenbergen MJ, Fens MHAM, van de Dikkenberg JB, et al. Folate-dactolisib conjugates for targeting tubular cells in polycystic kidneys. Journal of Controlled Release. 2019;293:113-25.
  • Shah VP, Crommelin DJA. Regulatory framework for biosimilars. Pharmaceutical Biotechnology: Fundamentals and Applications. 2019:265-74.
  • Schiffelers RM, Oude Blenke E, Mastrobattista E. Oligonucleotides. Pharmaceutical Biotechnology: Fundamentals and Applications. 2019:305-22.
  • Scheiner KC, Maas-Bakker RF, Nguyen TT, Duarte AM, Hendriks G, Sequeira L, et al. Sustained Release of Vascular Endothelial Growth Factor from Poly(ε-caprolactone-PEG-ε-caprolactone)‑b‑Poly(L‑lactide) Multiblock Copolymer Microspheres. ACS Omega. 2019;4(7):11481-92.
  • Sadeghi N, Kok RJ, Bos C, Zandvliet M, Geerts WJC, Storm G, et al. Hyperthermia-triggered release of hypoxic cell radiosensitizers from temperature-sensitive liposomes improves radiotherapy efficacy in vitro. Nanotechnology. 2019;30(26).
  • Rousou C, Hoogenboom P, van Overdam KA, Storm G, Dorrestijn J, Mastrobattista E. A technical protocol for an experimental ex vivo model using arterially perfused porcine eyes. Experimental Eye Research. 2019;181:171-7.
  • Roos E, Soer EC, Klompmaker S, Meijer LL, Besselink MG, Giovannetti E, et al. Crossing borders: A systematic review with quantitative analysis of genetic mutations of carcinomas of the biliary tract. Critical Reviews in Oncology/Hematology. 2019;140:8-16.
  • Ren JM, Knight AS, Van Ravensteijn BGP, Kohl P, Bou Zerdan R, Li Y, et al. DNA-Inspired Strand-Exchange for Switchable PMMA-Based Supramolecular Morphologies. Journal of the American Chemical Society. 2019;141(6):2630-5.
  • Reiniers MJ, de Haan L, Weijer R, Wiggers JK, Jongejan A, Moerland PD, et al. Effect of preoperative biliary drainage on cholestasis-associated inflammatory and fibrotic gene signatures in perihilar cholangiocarcinoma. British Journal of Surgery. 2019;106(1):55-8.
  • Pretini V, Koenen MH, Kaestner L, Fens MHAM, Schiffelers RM, Bartels M, et al. Red blood cells: Chasing interactions. Frontiers in Physiology. 2019;10(JUL).
  • Petre DG, Kucko NW, Abbadessa A, Vermonden T, Polini A, Leeuwenburgh SCG. Surface functionalization of polylactic acid fibers with alendronate groups does not improve the mechanical properties of fiber-reinforced calcium phosphate cements. Journal of the Mechanical Behavior of Biomedical Materials. 2019;90:472-83.
  • Ortega FG, Roefs MT, de Miguel Perez D, Kooijmans SA, de Jong OG, Sluijter JP, et al. Interfering with endolysosomal trafficking enhances release of bioactive exosomes. Nanomedicine: Nanotechnology, Biology, and Medicine. 2019;20.
  • Ojha T, Pathak V, Drude N, Weiler M, Rommel D, Rütten S, et al. Shelf-life evaluation and lyophilization of PBCA-based polymeric microbubbles. Pharmaceutics. 2019;11(9).
  • Nagórniewicz B, Mardhian DF, Booijink R, Storm G, Prakash J, Bansal R. Engineered Relaxin as theranostic nanomedicine to diagnose and ameliorate liver cirrhosis. Nanomedicine: Nanotechnology, Biology, and Medicine. 2019;17:106-18.
  • Murphy DE, de Jong OG, Brouwer M, Wood MJ, Lavieu G, Schiffelers RM, et al. Extracellular vesicle-based therapeutics: natural versus engineered targeting and trafficking. Experimental and Molecular Medicine. 2019;51(3).
  • Meijer LL, Puik JR, Le Large TYS, Heger M, Dijk F, Funel N, et al. Unravelling the diagnostic dilemma: A microrna panel of circulating MIR-16 and MIR-877 as a diagnostic classifier for distal bile duct tumors. Cancers. 2019;11(8).
  • Mashayekhi V, Op 'T Hoog C, Oliveira S. Vascular targeted photodynamic therapy: A review of the efforts towards molecular targeting of tumor vasculature. Journal of Porphyrins and Phthalocyanines. 2019;23(11-12):1229-40.
  • Martínez-Jothar L, Beztsinna N, Van Nostrum CF, Hennink WE, Oliveira S. Selective Cytotoxicity to HER2 Positive Breast Cancer Cells by Saporin-Loaded Nanobody-Targeted Polymeric Nanoparticles in Combination with Photochemical Internalization. Molecular Pharmaceutics. 2019;16(4):1633-47.
  • Lou B, De Beuckelaer A, Boonstra E, Li D, De Geest BG, De Koker S, et al. Modular core-shell polymeric nanoparticles mimicking viral structures for vaccination. Journal of Controlled Release. 2019;293:48-62.
  • Lou B, Connor K, Sweeney K, Miller IS, O’Farrell A, Ruiz-Hernandez E, et al. RGD-decorated cholesterol stabilized polyplexes for targeted siRNA delivery to glioblastoma cells. Drug Delivery and Translational Research. 2019;9(3):679-93.
  • Lammers T, Storm G. Setting standards to promote progress in bio–nano science. Nature Nanotechnology. 2019;14(7):626.
  • Kuninty PR, Bansal R, De Geus SWL, Mardhian DF, Schnittert J, van Baarlen J, et al. ITGA5 inhibition in pancreatic stellate cells attenuates desmoplasia and potentiates efficacy of chemotherapy in pancreatic cancer. Science Advances. 2019;5(9).
  • Kordalivand N, Tondini E, Lau CYJ, Vermonden T, Mastrobattista E, Hennink WE, et al. Cationic synthetic long peptides-loaded nanogels: An efficient therapeutic vaccine formulation for induction of T-cell responses. Journal of Controlled Release. 2019;315:114-25.
  • Kontturi LS, Van Den Dikkenberg J, Urtti A, Hennink WE, Mastrobattista E. Light-triggered cellular delivery of oligonucleotides. Pharmaceutics. 2019;11(2).
  • Klein K, Stolk P, De Bruin ML, Leufkens HGM, Crommelin DJA, De Vlieger JSB. The EU regulatory landscape of non-biological complex drugs (NBCDs) follow-on products: Observations and recommendations. European Journal of Pharmaceutical Sciences. 2019;133:228-35.
  • Jong JAW, Smakman R, Moret ME, Verhaar MC, Hennink WE, Gerritsen KGF, et al. Reactivity of (Vicinal) Carbonyl Compounds with Urea. ACS Omega. 2019;4(7):11928-37.
  • Jones DTW, Banito A, Grünewald TGP, Haber M, Jäger N, Kool M, et al. Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours. Nature Reviews Cancer. 2019;19(8):420-38.
  • Jiskoot W, Kersten GFA, Mastrobattista E, Slütter B. Vaccines. Pharmaceutical Biotechnology: Fundamentals and Applications. 2019:282-304.
  • Jiskoot W, Crommelin DJA. Biophysical and biochemical characteristics of therapeutic proteins. Pharmaceutical Biotechnology: Fundamentals and Applications. 2019:19-32.
  • Jansen K, Castilho M, Aarts S, Kaminski MM, Lienkamp SS, Pichler R, et al. Fabrication of Kidney Proximal Tubule Grafts Using Biofunctionalized Electrospun Polymer Scaffolds. Macromolecular Bioscience. 2019;19(2).
  • Herold S, Kalb J, Büchel G, Ade CP, Baluapuri A, Xu J, et al. Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase. Nature. 2019;567(7749):545-9.
  • Hennink WE, Sahay G. NanoDDS 2018: The 16th International Nanomedicine & Drug Delivery Symposium. Journal of Controlled Release. 2019;310:22-3.
  • Hennink WE, Paulusse JMJ. Editorial for 15th European symposium on controlled drug delivery. Journal of Controlled Release. 2019;297:1-2.
  • Hemelrijk SD, van Gulik TM, Heger M. Carotid chemoreceptor denervation does not impair hypoxia-induced thermal downregulation but vitiates recovery from a hypothermic and hypometabolic state in mice. Scientific Reports. 2019;9(1).
  • Hembury M, Beztsinna N, Asadi H, Van Den Dikkenberg JB, Meeldijk JD, Hennink WE, et al. Correction: Luminescent gold nanocluster-decorated polymeric hybrid particles with assembly-induced emission (Biomacromolecules (2018) 19:7 (2841-2848) DOI: 10.1021/acs.biomac.8b00414). Biomacromolecules. 2019;20(1):566.
  • Guo Y, Van Ravensteijn BGP, Kegel WK. Dimple Colloids with Tunable Cavity Size and Surface Functionalities. Macromolecules. 2019;52(11):4287-94.
  • Guerci P, Ergin B, Uz Z, Ince Y, Westphal M, Heger M, et al. Glycocalyx Degradation Is Independent of Vascular Barrier Permeability Increase in Nontraumatic Hemorrhagic Shock in Rats. Anesthesia and analgesia. 2019;129(2):598-607.
  • Giorgio E, Lorenzati M, Di Val Cervo PR, Brussino A, Cernigoj M, Sala ED, et al. Allele-specific silencing as treatment for gene duplication disorders: Proof-of-principle in autosomal dominant leukodystrophy. Brain. 2019;142(7):1905-20.
  • Fülöp T, Kozma GT, Vashegyi I, Mészáros T, Rosivall L, Urbanics R, et al. Liposome-induced hypersensitivity reactions: Risk reduction by design of safe infusion protocols in pigs. Journal of Controlled Release. 2019;309:333-8.
  • Fliervoet LAL, van Nostrum CF, Hennink WE, Vermonden T. Balancing hydrophobic and electrostatic interactions in thermosensitive polyplexes for nucleic acid delivery. Multifunctional Materials. 2019;2(2).
  • Fliervoet LAL, Lisitsyna ES, Durandin NA, Kotsis I, Maas-Bakker RFM, Yliperttula M, et al. Structure and Dynamics of Thermosensitive pDNA Polyplexes Studied by Time-Resolved Fluorescence Spectroscopy. Biomacromolecules. 2019.
  • Ferreira GS, Veening-Griffioen DH, Boon WPC, Moors EHM, Gispen-De Wied CC, Schellekens H, et al. Correction: A Standardised Framework to Identify Optimal Animal Models for Efficacy Assessment in Drug Development (PLoS ONE (2019) 14: 6 (e0218014) 10.1371/journal.pone.0218014). PLoS ONE. 2019;14(7).
  • Ferreira GS, Veening-Griffioen DH, Boon WPC, Moors EHM, De Wied CCG, Schellekens H, et al. A standardised framework to identify optimal animal models for efficacy assessment in drug development. PLoS ONE. 2019;14(6).
  • Ergen C, Niemietz PM, Heymann F, Baues M, Gremse F, Pola R, et al. Liver fibrosis affects the targeting properties of drug delivery systems to macrophage subsets in vivo. Biomaterials. 2019;206:49-60.
  • Ebbers HC, Schellekens H. Are we ready to close the discussion on the interchangeability of biosimilars? Drug Discovery Today. 2019;24(10):1963-7.
  • Deshantri AK, Metselaar JM, Zagkou S, Storm G, Mandhane SN, Fens MHAM, et al. Development and characterization of liposomal formulation of bortezomib. International Journal of Pharmaceutics: X. 2019;1.
  • Deshantri AK, Fens MH, Ruiter RWJ, Metselaar JM, Storm G, van Bloois L, et al. Liposomal dexamethasone inhibits tumor growth in an advanced human-mouse hybrid model of multiple myeloma. Journal of Controlled Release. 2019;296:232-40.
  • Den Hoedt CH, van Gelder MK, Grooteman MP, Nubé MJ, Blankestijn PJ, Goldschmeding R, et al. Connective tissue growth factor is related to all-cause mortality in hemodialysis patients and is lowered by on-line hemodiafiltration: Results from the convective transport study. Toxins. 2019;11(5).
  • de Vlieger JSB, Crommelin DJA, Tyner K, Drummond DC, Jiang W, McNeil SE, et al. Report of the AAPS Guidance Forum on the FDA Draft Guidance for Industry: “Drug Products, Including Biological Products, that Contain Nanomaterials”. AAPS Journal. 2019;21(4).
  • de Matos MBC, Miranda BS, Rizky Nuari Y, Storm G, Leneweit G, Schiffelers RM, et al. Liposomes with asymmetric bilayers produced from inverse emulsions for nucleic acid delivery. Journal of Drug Targeting. 2019;27(5-6):681-9.
  • De Matos MBC, Deckers R, Van Elburg B, Lajoinie G, De Miranda BS, Versluis M, et al. Ultrasound-sensitive liposomes for triggered macromolecular drug delivery: Formulation and in vitro characterization. Frontiers in Pharmacology. 2019;10.
  • de Jong OG, van der Waals LM, Kools FRW, Verhaar MC, van Balkom BWM. Lysyl oxidase-like 2 is a regulator of angiogenesis through modulation of endothelial-to-mesenchymal transition. Journal of Cellular Physiology. 2019;234(7):10260-9.
  • De Jong OG, Kooijmans SAA, Murphy DE, Jiang L, Evers MJW, Sluijter JPG, et al. Drug Delivery with Extracellular Vesicles: From Imagination to Innovation. Accounts of Chemical Research. 2019;52(7):1761-70.
  • De Groof TWM, Mashayekhi V, Fan TS, Bergkamp ND, Toraño JS, Van Senten JR, et al. Nanobody-Targeted Photodynamic Therapy Selectively Kills Viral GPCR-Expressing Glioblastoma Cells. Molecular Pharmaceutics. 2019.
  • Crommelin DJA, Sindelar RD, Meibohm B. Preface. Pharmaceutical Biotechnology: Fundamentals and Applications. 2019:vii-vii.
  • Crommelin DJA, Sindelar RD, Meibohm B. Pharmaceutical biotechnology: Fundamentals and applications. Pharmaceutical Biotechnology: Fundamentals and Applications. 2019:1-653.
  • Crommelin DJA, Hawe A, Jiskoot W. Formulation of biologics including biopharmaceutical considerations. Pharmaceutical Biotechnology: Fundamentals and Applications. 2019:83-103.
  • Claeys S, Denecker G, Durinck K, Decaesteker B, Mus LM, Loontiens S, et al. ALK positively regulates MYCN activity through repression of HBP1 expression. Oncogene. 2019;38(15):2690-705.
  • Chang F, Van Ravensteijn BGP, Lacina KS, Kegel WK. Bifunctional Janus Spheres with Chemically Orthogonal Patches. ACS Macro Letters. 2019;8(6):714-8.
  • Buwalda S, Nottelet B, Bethry A, Kok RJ, Sijbrandi N, Coudane J. Reversibly core-crosslinked PEG-P(HPMA) micelles: Platinum coordination chemistry for competitive-ligand-regulated drug delivery. Journal of Colloid and Interface Science. 2019;535:505-15.
  • Bresseleers J, Bagheri M, Storm G, Metselaar JM, Hennink WE, Meeuwissen SA, et al. Scale-Up of the Manufacturing Process to Produce Docetaxel-Loaded mPEG- b-p(HPMA-Bz) Block Copolymer Micelles for Pharmaceutical Applications. Organic Process Research and Development. 2019;23(12):2707-15.
  • Beltrán Hernández I, Rompen R, Rossin R, Xenaki KT, Katrukha EA, Nicolay K, et al. Imaging of Tumor Spheroids, Dual-Isotope SPECT, and Autoradiographic Analysis to Assess the Tumor Uptake and Distribution of Different Nanobodies. Molecular Imaging and Biology. 2019;21(6):1079-88.
  • Allijn IE, Brinkhuis RP, Storm G, Schiffelers RM. Anti-inflammatory properties of plant derived natural products – A systematic review. Current Medicinal Chemistry. 2019;26(24):4506-36.
  • Aldosari MH, de Vries RP, Rodriguez LR, Hesen NA, Beztsinna N, van Kuilenburg ABP, et al. Liposome-targeted recombinant human acid sphingomyelinase: Production, formulation, and in vitro evaluation. European Journal of Pharmaceutics and Biopharmaceutics. 2019;137:185-95.
  • Akcora BÖ, Dathathri E, Ortiz-Perez A, Gabriël AV, Storm G, Prakash J, et al. TG101348, a selective JAK2 antagonist, ameliorates hepatic fibrogenesis in vivo. FASEB Journal. 2019;33(8):9466-75.