Vincent Portegijs has been an employee of the University of Utrecht since 2002. On the way to completing his biochemistry degree at the polytechnics in Utrecht, he spent a year in Oakland, California at the group of Frans Kuypers at the Children's Hospital Research Institute (CHORI), studying the role of protein kinase C in the changes of the lipid bi-layer of erythrocytes. 

Upon joining the developmental biology group at the University of Utrecht, Vincent studied the effect of 5' UTR complexity on translation with dr. Adri Thomas, as well genotyping mouse mutations involved in mouse limb development and outgrowth. After the departure of the former professor of the group, projects have dealt with splicing, and hormone receptor binding. 

As of May 2005, Vincent returned to the developmental biology division as a lab technician, now headed by Prof. Dr. Sander van den Heuvel. Since, he has been dealing with general lab support, molecular cloning and C. elegans work and supervision of practical education. Starting july 2012 Vincent has started combining his work as a technician with a PhD working on the regulation of spindle positioning in asymmetric cell division using C. elegans as a model system.