Publications
2023
Scholarly publications
Gilbert, M. S., Cai, Y., Folkerts, G., Braber, S., & Gerrits, W. J. J. (2023). Effects of non-digestible oligosaccharides on inflammation, lung health and performance of calves. Journal of Dairy Science. Advance online publication. https://doi.org/10.3168/jds.2023-23887
Mavrogeni, M. E., Asadpoor, M., Judernatz, J. H., van Ark, I., Wösten, M. M. S. M., Strijbis, K., Pieters, R. J., Folkerts, G., & Braber, S. (2023). Protective Effects of Alginate and Chitosan Oligosaccharides against
Clostridioides difficile Bacteria and Toxin. Toxins, 15(10), 1-23. Article 586. https://doi.org/10.3390/toxins15100586
Wang, L., Cai, Y., Garssen, J., Henricks, P. A. J., Folkerts, G., & Braber, S. (2023). Reply to: Gut Microbiota Dysbiosis and Chronic Obstructive Pulmonary Disease: A Question of Chicken and Egg. American Journal of Respiratory and Critical Care Medicine, 208(11), 1240-1241. https://doi.org/10.1164/rccm.202308-1418LE, https://doi.org/10.1164/rccm.202308-1418LE
Zhu, H., Cai, Y., Slimmen, L. J. M., de Bruijn, A. C. J. M., van Rossum, A. M. C., Folkerts, G., Braber, S., & Unger, W. W. J. (2023). Galacto-Oligosaccharides as an Anti-Infective and Anti-Microbial Agent for Macrolide-Resistant and -Sensitive Mycoplasma pneumoniae. FEMS Microbiology Immunology, 12(5), Article 659. https://doi.org/10.3390/pathogens12050659
Wang, L., Cai, Y., Garssen, J., Henricks, P. A. J., Folkerts, G., & Braber, S. (2023). The Bidirectional Gut-Lung Axis in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine, 207(9), 1145-1160. https://doi.org/10.1164/rccm.202206-1066TR
https://dspace.library.uu.nl/bitstream/handle/1874/428222/rccm.202206_1066tr.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/428222/rccm.202206_1066tr.pdf?sequence=1
Lian, P., Henricks, P. A. J., Wichers, H. J., Folkerts, G., & Braber, S. (2023). Differential Effects of Oligosaccharides, Antioxidants, Amino Acids and PUFAs on Heat/Hypoxia-Induced Epithelial Injury in a Caco-2/HT-29 Co-Culture Model. International Journal of Molecular Sciences, 24(2), 1-20. Article 1111. https://doi.org/10.3390/ijms24021111
2022
Scholarly publications
Cai, Y., Folkerts, G., & Braber, S. (2022). Non-Digestible Oligosaccharides: A Novel Treatment for Respiratory Infections? Nutrients, 14(23), 1-11. Article 5033. https://doi.org/10.3390/nu14235033
Pelgrim, C. E., van Ark, I., van Berkum, R. E., Schuitemaker-Borneman, A. M., Flier, I., Leusink-Muis, T., Janbazacyabar, H., Diks, M. A. P., Gosker, H. R., Kelders, M. C. J. M., Langen, R. C. J., Schols, A. M. W. J., Hageman, R. J. J., Braber, S., Garssen, J., Folkerts, G., van Helvoort, A., & Kraneveld, A. D. (2022). Effects of a nutritional intervention on impaired behavior and cognitive function in an emphysematous murine model of COPD with endotoxin-induced lung inflammation. Frontiers in Nutrition, 9, Article 1010989. https://doi.org/10.3389/fnut.2022.1010989
Mavrogeni, M. E., Asadpoor, M., Henricks, P. A. J., Keshavarzian, A., Folkerts, G., & Braber, S. (2022). Direct Action of Non-Digestible Oligosaccharides against a Leaky Gut. Nutrients, 14(21), Article 4699. https://doi.org/10.3390/nu14214699
Wang, L., van Iersel, L. E. J., Pelgrim, C. E., Lu, J., van Ark, I., Leusink-Muis, T., Gosker, H. R., Langen, R. C. J., Schols, A. M. W. J., Argilés, J. M., van Helvoort, A., Kraneveld, A. D., Garssen, J., Henricks, P. A. J., Folkerts, G., & Braber, S. (2022). Effects of Cigarette Smoke on Adipose and Skeletal Muscle Tissue: In Vivo and In Vitro Studies. Cells, 11(18), 1-20. Article 2893. https://doi.org/10.3390/cells11182893
Toutounchi, N. S., Braber, S., Land, B. V., Thijssen, S., Garssen, J., Folkerts, G., & Hogenkamp, A. (2022). Deoxynivalenol exposure during pregnancy has adverse effects on placental structure and immunity in mice model. Reproductive Toxicology, 112, 109-118. https://doi.org/10.1016/j.reprotox.2022.07.002
Wang, L., Pelgrim, C. E., Peralta Marzal, L. N., Korver, S., van Ark, I., Leusink-Muis, T., van Helvoort, A., Keshavarian, A., Kraneveld, A. D., Garssen, J., Henricks, P. A. J., Folkerts, G., & Braber, S. (2022). Changes in intestinal homeostasis and immunity in a cigarette smoke- and LPS-induced murine model for COPD: the lung-gut axis. American journal of physiology. Lung cellular and molecular physiology, 323(3), L266-L280. https://doi.org/10.1152/ajplung.00486.2021
Pelgrim, C. E., Wang, L., Peralta Marzal, L. N., Korver, S., van Ark, I., Leusink-Muis, T., Braber, S., Folkerts, G., Garssen, J., van Helvoort, A., & Kraneveld, A. D. (2022). Increased exploration and hyperlocomotion in a cigarette smoke and LPS induced murine model of COPD: linking pulmonary and systemic inflammation with the brain. American journal of physiology. Lung cellular and molecular physiology, 323(3), L251-L265. https://doi.org/10.1152/ajplung.00485.2021
Janbazacyabar, H., van Bergenhenegouwen, J., Varasteh, S., Garssen, J., Folkerts, G., & Braber, S. (2022). Repeated exposure of bronchial epithelial cells to particular matter increases allergen-induced cytokine release and permeability. Cytokine, 154, 1-11. Article 155878. https://doi.org/10.1016/j.cyto.2022.155878
Cai, Y., van Putten, J. P. M., Gilbert, M. S., Gerrits, W. J. J., Folkerts, G., & Braber, S. (2022). Galacto-oligosaccharides as an anti-bacterial and anti-invasive agent in lung infections. Biomaterials, 283, 1-18. Article 121461. https://doi.org/10.1016/j.biomaterials.2022.121461
Keulers, L., Dehghani, A., Knippels, L., Garssen, J., Papadopoulos, N., Folkerts, G., Braber, S., & van Bergenhenegouwen, J. (2022). Probiotics, prebiotics, and synbiotics to prevent or combat air pollution consequences: The gut-lung axis. Environmental pollution (Barking, Essex : 1987), 302, 1-14. Article 119066. https://doi.org/10.1016/j.envpol.2022.119066
Alizadeh, A., Akbari, P., Garssen, J., Fink-Gremmels, J., & Braber, S. (2022). Epithelial integrity, junctional complexes, and biomarkers associated with intestinal functions. Tissue Barriers, 10(3), 1-21. Article 1996830. https://doi.org/10.1080/21688370.2021.1996830
Pelgrim, C. E., van Ark, I., Leusink-Muis, T., Brans, M. A. D., Braber, S., Garssen, J., van Helvoort, A., Kraneveld, A. D., & Folkerts, G. (2022). Intratracheal administration of solutions in mice; development and validation of an optimized method with improved efficacy, reproducibility and accuracy. Journal of Pharmacological and Toxicological Methods, 114, 1-7. Article 107156. https://doi.org/10.1016/j.vascn.2022.107156
Cai, Y., Gilbert, M. S., Gerrits, W. J. J., Folkerts, G., & Braber, S. (2022). Galacto-oligosaccharides alleviate lung inflammation by inhibiting NLRP3 inflammasome activation in vivo and in vitro. Journal of Advanced Research, 39, 305-318. https://doi.org/10.1016/j.jare.2021.10.013
2021
Scholarly publications
Janbazacyabar, H., van Bergenhenegouwen, J., Garssen, J., Leusink-Muis, T., Ark, I. V., van Daal, M. T., Folkerts, G., & Braber, S. (2021). Prenatal and Postnatal Cigarette Smoke Exposure Is Associated With Increased Risk of Exacerbated Allergic Airway Immune Responses: A Preclinical Mouse Model. Frontiers in Immunology, 12, 1-14. Article 797376. https://doi.org/10.3389/fimmu.2021.797376
Seyed Toutounchi, N., Braber, S., van’t Land, B., Thijssen, S., Garssen, J., Kraneveld, A. D., Folkerts, G., & Hogenkamp, A. (2021). Exposure to Deoxynivalenol During Pregnancy and Lactation Enhances Food Allergy and Reduces Vaccine Responsiveness in the Offspring in a Mouse Model. Frontiers in Immunology, 12, 1-15. Article 797152. https://doi.org/10.3389/fimmu.2021.797152
van Daal, M. T., Folkerts, G., Garssen, J., & Braber, S. (2021). Pharmacological Modulation of Immune Responses by Nutritional Components. Pharmacological Reviews, 73(4), 198-232. https://doi.org/10.1124/pharmrev.120.000063
Cai, Y., Gilbert, M. S., Gerrits, W. J. J., Folkerts, G., & Braber, S. (2021). Anti-inflammatory properties of fructo-oligosaccharides in a calf lung infection model and in mannheimia haemolytica-infected airway epithelial cells. Nutrients, 13(10), 1-19. Article 3514. https://doi.org/10.3390/nu13103514
Asadpoor, M., Ithakisiou, G.-N., van Putten, J. P. M., Pieters, R. J., Folkerts, G., & Braber, S. (2021). Antimicrobial Activities of Alginate and Chitosan Oligosaccharides Against Staphylococcus aureus and Group B Streptococcus. Frontiers in Microbiology, 12, 1-15. Article 700605. https://doi.org/10.3389/fmicb.2021.700605
Toutounchi, N. S., Braber, S., Hogenkamp, A., Varasteh, S., Cai, Y., Wehkamp, T., Tims, S., Leusink-Muis, T., van Ark, I., Wiertsema, S., Stahl, B., Kraneveld, A. D., Garssen, J., Folkerts, G., & Van’T Land, B. (2021). Human milk oligosaccharide 3′-gl improves influenza-specific vaccination responsiveness and immunity after deoxynivalenol exposure in preclinical models. Nutrients, 13(9), Article 3190. https://doi.org/10.3390/nu13093190
Janbazacyabar, H., van Daal, M., Leusink-Muis, T., van Ark, I., Garssen, J., Folkerts, G., van Bergenhenegouwen, J., & Braber, S. (2021). The Effects of Maternal Smoking on Pregnancy and Offspring: Possible Role for EGF? Frontiers in Cell and Developmental Biology, 9, 1-15. Article 680902. https://doi.org/10.3389/fcell.2021.680902
Asadpoor, M., Varasteh, S., Pieters, R., Folkerts, G., & Braber, S. (2021). Differential effects of oligosaccharides on the effectiveness of ampicillin against Escherichia coli in vitro. PharmaNutrition, 16(6), 1-9. Article 100264. https://doi.org/10.1016/j.phanu.2021.100264
Lian, P., Braber, S., Varasteh, S., Wichers, H. J., & Folkerts, G. (2021). Hypoxia and heat stress affect epithelial integrity in a Caco-2/HT-29 co-culture. Scientific Reports, 11(1), Article 13186. https://doi.org/10.1038/s41598-021-92574-5
Wang, L., Pelgrim, C. E., Swart, D. H., Krenning, G., van der Graaf, A. C., Kraneveld, A. D., Leusink-Muis, T., van Ark, I., Garssen, J., Folkerts, G., & Braber, S. (2021). SUL-151 Decreases Airway Neutrophilia as a Prophylactic and Therapeutic Treatment in Mice after Cigarette Smoke Exposure. International Journal of Molecular Sciences, 22(9), 1-17. Article 4991. https://doi.org/10.3390/ijms22094991
Haksar, D., Asadpoor, M., Heise, T., Shi, J., Braber, S., Folkerts, G., Ballell, L., Rodrigues, J., & Pieters, R. J. (2021). Fighting Shigella by Blocking Its Disease-Causing Toxin. Journal of Medicinal Chemistry, 64(9), 6059-6069. https://doi.org/10.1021/acs.jmedchem.1c00152
Asadpoor, M., Ithakisiou, G.-N., Henricks, P. A. J., Pieters, R., Folkerts, G., & Braber, S. (2021). Non-Digestible Oligosaccharides and Short Chain Fatty Acids as Therapeutic Targets against Enterotoxin-Producing Bacteria and Their Toxins. Toxins, 13(3), Article 175. https://doi.org/10.3390/TOXINS13030175
2020
Scholarly publications
Ghiamati Yazdi, F., Zakeri, A., Ark, I. V., Leusink-Muis, T., Braber, S., Soleimanian-Zad, S., & Folkerts, G. (2020). Crude Turmeric Extract Improves the Suppressive Effects of Lactobacillus rhamnosus GG on Allergic Inflammation in a Murine Model of House Dust Mite-Induced Asthma. Frontiers in Immunology, 11, Article 1092. https://doi.org/10.3389/fimmu.2020.01092
Asadpoor, M., Peeters, C., Henricks, P. A. J., Varasteh, S., Pieters, R. J., Folkerts, G., & Braber, S. (2020). Anti-pathogenic functions of non-digestible oligosaccharides in vitro. Nutrients, 12(6), Article 1789. https://doi.org/10.3390/nu12061789
Cai, Y., Varasteh, S., van Putten, J. P. M., Folkerts, G., & Braber, S. (2020). Mannheimia haemolytica and lipopolysaccharide induce airway epithelial inflammatory responses in an extensively developed ex vivo calf model. Scientific Reports, 10(1), Article 13042. https://doi.org/10.1038/s41598-020-69982-0
Lian, P., Braber, S., Garssen, J., Wichers, H. J., Folkerts, G., Fink-Gremmels, J., & Varasteh, S. (2020). Beyond heat stress: Intestinal integrity disruption and mechanism-based intervention strategies. Nutrients, 12(3), Article 734. https://doi.org/10.3390/nu12030734
Cai, Y., Folkerts, J., Folkerts, G., Maurer, M., & Braber, S. (2020). Microbiota-dependent and -independent effects of dietary fiber on human health. British Journal of Pharmacology, 177(6), 1363-1381. https://doi.org/10.1111/bph.14871
2019
Scholarly publications
Braber, S., Bol-Schoenmakers, M., Akbari, P., Jeurink, P. V., Graaff, P. D., Smit, J. J., Van Esch, B. C. A. M., Garssen, J., Fink-Gremmels, J., & Pieters, R. H. H. (2019). Allergic Sensitization to Whey in Mice Is Facilitated By the Mycotoxin Deoxynivalenol (DON). 75-76. Abstract from World allergy congress, Seoul, Korea, Republic of. https://doi.org/10.1186/s40413-016-0096-1
Toutounchi, N. S., Hogenkamp, A., Varasteh, S., Land, B. V. T., Garssen, J., Kraneveld, A. D., Folkerts, G., & Braber, S. (2019). Fusarium mycotoxins disrupt the barrier and induce IL-6 release in a human placental epithelium cell line. Toxins, 11(11), Article 665. https://doi.org/10.3390/toxins11110665
Janbazacyabar, H., van Bergenhenegouwen, J., Verheijden, K. A. T., Leusink-Muis, T., van Helvoort, A., Garssen, J., Folkerts, G., & Braber, S. (2019). Non-digestible oligosaccharides partially prevent the development of LPS-induced lung emphysema in mice. PharmaNutrition, 10, Article 100163. https://doi.org/10.1016/j.phanu.2019.100163
2018
Scholarly publications
Varasteh, S., Braber, S., Kraneveld, A. D., Garssen, J., & Fink-Gremmels, J. (2018). Heat stress alters the gene expression of nutrient transporters along the chicken small intestine and dietary galacto-oligosaccharides are able to modulate this response. 143. https://doi.org/10.1111/jvp.12659
van Bergenhenegouwen, J., Braber, S., Loonstra, R., Buurman, N., Rutten, L., Knipping, K., Savelkoul, P. J., Harthoorn, L. F., Jahnsen, F. L., Garssen, J., & Hartog, A. (2018). Oral exposure to the free amino acid glycine inhibits the acute allergic response in a model of cow's milk allergy in mice. Nutrition Research, 58, 95-105. https://doi.org/10.1016/j.nutres.2018.07.005
Verheijden, K. A. T., Braber, S., Leusink-Muis, T., Jeurink, P. V., Thijssen, S., Kraneveld, A. D., Garssen, J., Folkerts, G., & Willemsen, L. E. M. (2018). The Combination Therapy of Dietary Galacto-Oligosaccharides With Budesonide Reduces Pulmonary Th2 Driving Mediators and Mast Cell Degranulation in a Murine Model of House Dust Mite Induced Asthma. Frontiers in Immunology, 9, Article 2419. https://doi.org/10.3389/fimmu.2018.02419
Varasteh, S., Fink-Gremmels, J., Garssen, J., & Braber, S. (2018). α-Lipoic acid prevents the intestinal epithelial monolayer damage under heat stress conditions: model experiments in Caco-2 cells. European Journal of Nutrition, 57(4), 1577-1589. https://doi.org/10.1007/s00394-017-1442-y
Brugman, S., Ikeda-Ohtsubo, W., Braber, S., Folkerts, G., Pieterse, C. M. J., & Bakker, P. A. H. M. (2018). A comparative review on microbiota manipulation: Lessons from fish, plants, livestock, and human research. Frontiers in Nutrition, 5, Article 80. https://doi.org/10.3389/fnut.2018.00080
Varasteh, S., Braber, S., Kraneveld, A. D., Garssen, J., & Fink-Gremmels, J. (2018). L-Arginine supplementation prevents intestinal epithelial barrier breakdown under heat stress conditions by promoting nitric oxide synthesis. Nutrition Research, 57, 45-55. https://doi.org/10.1016/j.nutres.2018.05.007
2017
Scholarly publications
Asadi-Azarbaijani, B., Santos, R. R., Jahnukainen, K., Braber, S., van Duursen, M. B. M., Toppari, J., Saugstad, O. D., Nurmio, M., & Oskam, I. C. (2017). Developmental effects of imatinib mesylate on follicle assembly and early activation of primordial follicle pool in postnatal rat ovary. Reproductive Biology, 17(1), 25-33. https://doi.org/10.1016/j.repbio.2016.11.003
Akbari, P., Fink-Gremmels, J., Willems, R. H. A. M., Difilippo, E., Schols, H. A., Schoterman, M. H. C., Garssen, J., & Braber, S. (2017). Characterizing microbiota-independent effects of oligosaccharides on intestinal epithelial cells: insight into the role of structure and size: Structure–activity relationships of non-digestible oligosaccharides. European Journal of Nutrition, 56, 1919-1930. https://doi.org/10.1007/s00394-016-1234-9
Akbari, P., Braber, S., Varasteh, S., Alizadeh, A., Garssen, J., & Fink-Gremmels, J. (2017). The intestinal barrier as an emerging target in the toxicological assessment of mycotoxins. Archives of Toxicology, 91, 1007-1029. https://doi.org/10.1007/s00204-016-1794-8
2016
Scholarly publications
Verheijden, K. A. T., Braber, S., Leusink-Muis, T., Thijssen, S., Boon, L., Kraneveld, A. D., Garssen, J., Folkerts, G., & Willemsen, L. E. M. (2016). Regulatory T cell depletion abolishes the protective effect of dietary galactooligosaccharides on eosinophilic airway inflammation in house dust mite-induced asthma. Allergy: European Journal of Allergy and Clinical Immunology, 71, 229-230. https://doi.org/10.1111/all.12972
Hogenkamp, A., Jeurink, P., Thijssen, S., Alizadeh, A., Fink-Gremmels, J., Garssen, J., Braber, S., & Veening-Griffioen, D. (2016). Impact of early life exposure to the mycotoxin DON on the development of food allergy. Allergy: European Journal of Allergy and Clinical Immunology, 71, 159. https://doi.org/10.1111/all.12972
Difilippo, E., Pan, F., Logtenberg, M., Willems, R. H. A. M., Braber, S., Fink-Gremmels, J., Schols, H. A., & Gruppen, H. (2016). Milk Oligosaccharide Variation in Sow Milk and Milk Oligosaccharide Fermentation in Piglet Intestine. Journal of Agricultural and Food Chemistry, 64(10), 2087-93. https://doi.org/10.1021/acs.jafc.6b00497
Difilippo, E., Pan, F., Logtenberg, M., Willems, R. H. A. M., Braber, S., Fink-Gremmels, J., Schols, H. A., & Gruppen, H. (2016). In Vitro Fermentation of Porcine Milk Oligosaccharides and Galacto-oligosaccharides Using Piglet Fecal Inoculum. Journal of Agricultural and Food Chemistry, 64(10), 2127-33. https://doi.org/10.1021/acs.jafc.5b05384
Veening-Griffioen, D., Wehkamp, T., Braber, S., Garssen, J., Knippels, L., & Jeurink, P. (2016). Dietary non-digestible oligosaccharides reduce the sensitizing capacity of deoxynivalenol in a dose-dependent manner. Allergy: European Journal of Allergy and Clinical Immunology, 71, 496-497. https://doi.org/10.1111/all.12976
Alizadeh, A., Braber, S., Akbari, P., Kraneveld, A., Garssen, J., & Fink-Gremmels, J. (2016). Deoxynivalenol and Its Modified Forms: Are There Major Differences? Toxins, 8(11). https://doi.org/10.3390/toxins8110334
Verheijden, K. A., Braber, S., Leusink-Muis, T., Thijssen, S., Boon, L., Kraneveld, A. D., Garssen, J., Folkerts, G., & Willemsen, L. E. (2016). Regulatory T Cell Depletion Abolishes the Protective Effect of Dietary Galacto-Oligosaccharides on Eosinophilic Airway Inflammation in House Dust Mite-Induced Asthma in Mice. Journal of Nutrition, 146(4), 831-837. https://doi.org/10.3945/jn.115.224402
Bol-Schoenmakers, M., Braber, S., Akbari, P., de Graaff, P., van Roest, M., Kruijssen, L., Smit, J. J., van Esch, B. C. A. M., Jeurink, P. V., Garssen, J., Fink-Gremmels, J., & Pieters, R. H. H. (2016). The mycotoxin deoxynivalenol facilitates allergic sensitization to whey in mice. Mucosal Immunology. https://doi.org/10.1038/mi.2016.13
Alizadeh, A., Akbari, P., Difilippo, E., Schols, H. A., Ulfman, L. H., Schoterman, M. H. C., Garssen, J., Fink-Gremmels, J., & Braber, S. (2016). The piglet as a model for studying dietary components in infant diets: effects of galacto-oligosaccharides on intestinal functions. British Journal of Nutrition, 115(4), 605-618. https://doi.org/10.1017/S0007114515004997
Verheijden, K. A. T., Willemsen, L. E. M., Braber, S., Leusink-Muis, T., Jeurink, P. V., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2016). The development of allergic inflammation in a murine house dust mite asthma model is suppressed by synbiotic mixtures of non-digestible oligosaccharides and Bifidobacterium breve M-16V. European Journal of Nutrition, 55(3), 1141-1151. https://doi.org/10.1007/s00394-015-0928-8
2015
Scholarly publications
Difilippo, E., Bettonvil, M., Willems, R. H. A. M., Braber, S., Fink-Gremmels, J., Jeurink, P. V., Schoterman, M. H. C., Gruppen, H., & Schols, H. A. (2015). Oligosaccharides in Urine, Blood, and Feces of Piglets Fed Milk Replacer Containing Galacto-oligosaccharides. Journal of Agricultural and Food Chemistry, 63(50), 10862-10872. https://doi.org/10.1021/acs.jafc.5b04449
Verheijden, K. A. T., Akbari, P., Willemsen, L. E. M., Kraneveld, A. D., Folkerts, G., Garssen, J., Fink-Gremmels, J., & Braber, S. (2015). Inflammation-induced expression of the alarmin interleukin 33 can be suppressed by galacto-oligosaccharides. International Archives of Allergy and Immunology, 167(2), 127-136. https://doi.org/10.1159/000437327
Varasteh, S., Braber, S., Akbari, P., Garssen, J., & Fink-Gremmels, J. (2015). Differences in Susceptibility to Heat Stress along the Chicken Intestine and the Protective Effects of Galacto-Oligosaccharides. PLoS One, 10(9), Article e0138975. https://doi.org/10.1371/journal.pone.0138975
Alizadeh, A., Braber, S., Akbari, P., Garssen, J., & Fink-Gremmels, J. (2015). Deoxynivalenol Impairs Weight Gain and Affects Markers of Gut Health after Low-Dose, Short-Term Exposure of Growing Pigs. Toxins, 7(6), 2071-2095. https://doi.org/10.3390/toxins7062071
Varasteh, S., Braber, S., Garssen, J., & Fink-Gremmels, J. (2015). Galacto-oligosaccharides exert a protective effect against heat stress in a Caco-2 cell model. Journal of Functional Foods, 16, 265-277. https://doi.org/10.1016/j.jff.2015.04.045
Verheijden, K. A. T., Willemsen, L. E. M., Braber, S., Leusink-Muis, T., Delsing, D. J. M., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2015). Dietary galacto-oligosaccharides prevent airway eosinophilia and hyperresponsiveness in a murine house dust mite-induced asthma model. Respiratory Research, 16, 17. https://doi.org/10.1186/s12931-015-0171-0
Akbari, P., Braber, S., Alizadeh, A., Verheijden, K., Schoterman, M. H., Kraneveld, A. D., Garssen, J., & Fink-Gremmels, J. (2015). Galacto-oligosaccharides Protect the Intestinal Barrier by Maintaining the Tight Junction Network and Modulating the Inflammatory Responses after a Challenge with the Mycotoxin Deoxynivalenol in Human Caco-2 Cell Monolayers and B6C3F1 Mice. Journal of Nutrition, 145(7), 1604-1613. https://doi.org/10.3945/jn.114.209486
Other output
Bol-Schoenmakers, M., Braber, S., Akbari, P., Jeurink, P., De Graaff, P., Smit, J. J., Van Esch, B., Garssen, J., Fink-Gremmels, J., & Pieters, R. H. H. (2015). The mycotoxin deoxynivalenol (DON) facilitates allergic sensitization to whey in mice. Allergy, 70, 17. https://doi.org/10.1111/all.12715
2014
Scholarly publications
Verheijden, K., Willemsen, L. E. M., Braber, S., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2014). The preventive effects of dietary galacto-oligosaccharides in a house dust mite-induced asthma model in mice. Allergy, 69, 467. https://doi.org/10.1111/all.12478
Verheijden, K., Willemsen, L., Braber, S., Garssen, J., Kraneveld, A., & Folkerts, G. (2014). Dietary intervention with galactooligosaccharides is as effective or may be more effective as the treatment with the corticosteroid, budesonide, in a house dust mite-induced model of allergic asthma. Basic & Clinical Pharmacology & Toxicology, 115, 289-290.
Verheijden, K. A. T., Willemsen, L. E. M., Braber, S., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2014). A combination of fructo-oligosaccharides and Bifidobacterium breve M-16V suppresses airway resistance and inflammation in house dust mite allergic mice. Allergy, 69, 467-468. https://doi.org/10.1111/all.12478
Abdul Roda, M., Sadik, M., Gaggar, A., Hardison, M. T., Jablonsky, M. J., Braber, S., Blalock, J. E., Redegeld, F. A., Folkerts, G., & Jackson, P. L. (2014). Targeting prolyl endopeptidase with valproic acid as a potential modulator of neutrophilic inflammation. PLoS One, 9(5), Article e97594. https://doi.org/10.1371/journal.pone.0097594
Akbari, P., Braber, S., Gremmels, H., Koelink, P. J., Verheijden, K. A. T., Garssen, J., & Fink-Gremmels, J. (2014). Deoxynivalenol: a trigger for intestinal integrity breakdown. FASEB Journal, 28(6), 2414-2429.
2013
Scholarly publications
Overbeek, S. A., Braber, S., Koelink, P. J., Henricks, P. A. J., Mortaz, E., LoTam Loi, A. T., Jackson, P. L., Garssen, J., Wagenaar, G. T. M., Timens, W., Koenderman, L., Blalock, J. E., Kraneveld, A. D., & Folkerts, G. (2013). Cigarette Smoke-Induced Collagen Destruction; Key to Chronic Neutrophilic Airway Inflammation? PLoS One, 8(1), Article e55612. https://doi.org/10.1371/journal.pone.0055612
2012
Scholarly publications
Koelink, P. J., Overbeek, S. A., Braber, S., Morgan, M. E., Henricks, P. A., Verspaget, H. W., Wolfkamp, S. C., Te Velde, A. A., Jackson, P. L., Blalock, J. E., Garssen, J., Folkerts, G., & Kraneveld, A. D. (2012). Collagen proteolysis is important in neutrophilic intestinal auto-inflammation found in inflammatory bowel disease via proline-glycine-proline. Gastroenterology, 142(5), 883.
Akbari, P., Braber, S., Kraneveld, A. D., Garssen, J., & Fink-Gremmels, J. (2012). Deoxynivalenol impairs the intestinal barrier by disrupting the tight junction network. Journal of Veterinary Pharmacology and Therapeutics, 35, 93. https://doi.org/10.1111/jvp.12005
Braber, S., Akbari, P., Kraneveld, A. D., Folkerts, G., Garssen, J., & Fink-Gremmels, J. (2012). Oligosaccharides: A promising new approach for minimizing the pathological effects of deoxynivalenol on the intestinal tract. Journal of Veterinary Pharmacology and Therapeutics, 35, 49-50. https://doi.org/10.1111/jvp.12004
Braber, S., Thio, M., Blokhuis, B. R. J., Henricks, P. A. J., Koelink, P. J., Groot Kormelink, T., Bezemer, G. F. G., Kerstjens, H. A. M., Postma, D. S., Garssen, J., Kraneveld, A. D., Redegeld, F. A. M., & Folkerts, G. (2012). An association between neutrophils and immunoglobulin free light chains in the pathogenesis of chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine, 185(8), 817-24.
Koelink, P. J., Overbeek, S. A., Braber, S., de Kruijf, P., Folkerts, G., Smit, M. J., & Kraneveld, A. D. (2012). Targeting chemokine receptors in chronic inflammatory diseases: an extensive review. Pharmacology & Therapeutics, 133(1), 1-18. http://www.ncbi.nlm.nih.gov/pubmed/21839114
Other output
Abdul Roda, M., Gaggar, A., Blalock, J. E., Jackson, P. L., Braber, S., Hardison, M. T., Redegeld, F., & Folkerts, G. (2012). Targeting prolyl endopeptidase in chronic obstructive pulmonary disease.
2011
Scholarly publications
Braber, S., Koelink, P. J., Henricks, P. A. J., Jackson, P. L., Nijkamp, F. P., Garssen, J., Kraneveld, A. D., Blalock, J. E., & Folkerts, G. (2011). Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown. American journal of physiology. Lung cellular and molecular physiology, 300(2), L255-L265. https://doi.org/10.1152/ajplung.00304.2010
Overbeek, S. A., Braber, S., Henricks, P. A. J., Kleinjan, M., Kamp, V. M., Georgiou, N. A., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2011). Cigarette smoke induces β2-integrin-dependent neutrophil migration across human endothelium. Respiratory Research, 12, 75.
Braber, S., Overbeek, S. A., Koelink, P. J., Henricks, P. A. J., Zaman, G. J. R., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2011). CXCR2 antagonists block the N-Ac-PGP-induced neutrophil influx in the airways of mice, but not the production of the chemokine CXCL1. European Journal of Pharmacology, 668(3), 443-449. https://doi.org/10.1016/j.ejphar.2011.03.025
Braber, S. (2011). The pathogenesis of lung emphysema: lessons learned from murine models. [Doctoral thesis 1 (Research UU / Graduation UU), Utrecht University]. Utrecht University.
https://dspace.library.uu.nl/bitstream/handle/1874/205182/braber.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/205182/braber.pdf?sequence=1
Overbeek, S. A., Braber, S., Henricks, P. A. J., Kleinjan, M., Kamp, V. M., Georgiou, N. A., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2011). Cigarette smoke induces beta2-integrin-dependent neutrophil migration across human endothelium. Respiratory Research, 12, 75.
Other output
Overbeek, S., Braber, S., Henricks, P., Kleinjan, M., Kamp, V., Georgiou, N., Garssen, J., Kraneveld, A., & Folkerts, G. (2011). Cigarette smoke induces β2-integrin-dependent neutrophil migration across human umbilical vein endothelium.
2010
Scholarly publications
Folkerts, G., Blalock, E., Braber, S., Kraneveld, A., & Nijkamp, F. (2010). CXC chemokines and antagonists in chronic airway inflammation. Basic & Clinical Pharmacology & Toxicology, 107, 35-36. https://doi.org/10.1111/j.1742-7843.2010.00598-2.x
Braber, S., Henricks, P. A. J., Nijkamp, F. P., Kraneveld, A. D., & Folkerts, G. (2010). Inflammatory changes in the airways of mice caused by cigarette smoke exposure are only partially reversed after smoking cessation. Respiratory Research, 11(99), 1-11. http://respiratory-research.com/content/11/1/99
Braber, S., Verheijden, K. A. T., Henricks, P. A. J., Kraneveld, A. D., & Folkerts, G. (2010). A comparison of fixation methods on lung morphology in a murine model of emphysema. American journal of physiology. Lung cellular and molecular physiology, 299(6), L843-51.
Other output
Overbeek, S. A., Braber, S., Henricks, P. A. J., Kraneveld, A. D., Blalock, J. E., Nijkamp, F., & Folkerts, G. (2010). Exposure of human neutrophils to cigarette smoke or N-acetyl proline-glycine-proline results in CXCL8 and matrix metalloprotease 8 and 9 release.
Braber, S., Overbeek, S. A., Bezemer, G. F. G., Nijkamp, F., Henricks, P. A. J., Jackson, P. L., Blalock, J. E., Kraneveld, A. D., & Folkerts, G. (2010). Prolyl Endopeptidase (PE): An important enzyme involved in the development of lung emphysema?.
Braber, S., Overbeek, S. A., Bezemer, G. F. G., Henricks, P. A. J., Kraneveld, A. D., Folkerts, G., & Nijkamp, F. (2010). Smoking cessation reduces cytokine and chemokine levels but increases IL-10 in a mouse model for lung emphysema.
Overbeek, S. A., Braber, S., Henricks, P. A. J., Kraneveld, A. D., Nijkamp, F., & Folkerts, G. (2010). Human neutrophils stimulated with collagen breakdown product PGP results in chemotaxis, instant calcium influx and CXCL8 release.
2009
Scholarly publications
Braber, S., Hartog, A., Van Bergen-Henegouwen, J., Kraneveld, A. D., Folkerts, G., & Garssen, J. (2009). The role of collagen breakdown products inosteoarthritis. Naunyn-Schmiedeberg's Archives of Pharmacology, 379(2), 201. https://doi.org/10.1007/s00210-008-0340-5
Mortaz, E., Braber, S., Nazary, M., Givi, M. E., Nijkamp, F., & Folkerts, G. (2009). ATP in the pathogenesis of lung emphysema. European Journal of Pharmacology, 619(1-3), 92-96. https://doi.org/10.1016/j.ejphar.2009.07.022
Other output
Braber, S., Nijkamp, F. P., Henricks, P. A. J., Blalock, J. E., Kraneveld, A. D., & Folkerts, G. (2009). Prolyl Endopeptidase (PE): an important enzyme involved in the development of lung emphysema?. Poster session presented at TiPharma Spring meeting, Utrecht, NL.
2008
Other output
Braber, S., Blokhuis, B. R. J., Redegeld, F. A. M., Kraneveld, A. D., & Folkerts, G. (2008). Free immunoglobulin light chains in COPD models. Poster session presented at FIGON Dutch Medicins Days, Lunteren, Nederland.
2007
Other output
Braber, S., den Hartog, A., van Bergenhenegouwen, B. J., Kraneveld, A. D., Folkerts, G., & Garssen, J. (2007). The role of collagen breakdown products in osteoarthritis. Poster session presented at FIGON Medicines Days 2007, Lunteren, Nederland.