Publications
2023
Scholarly publications
Lozano-Andrés, E., Enciso-Martinez, A., Gijsbers, A., Ridolfi, A., Van Niel, G., Libregts, S. F. W. M., Pinheiro, C., van Herwijnen, M. J. C., Hendrix, A., Brucale, M., Valle, F., Peters, P. J., Otto, C., Arkesteijn, G. J. A., & Wauben, M. H. M. (2023). Physical association of low density lipoprotein particles and extracellular vesicles unveiled by single particle analysis. Journal of Extracellular Vesicles, 12(11), Article 12376. https://doi.org/10.1002/jev2.12376
Ridolfi, A., Cardellini, J., Gashi, F., van Herwijnen, M. J. C., Trulsson, M., Campos-Terán, J., H M Wauben, M., Berti, D., Nylander, T., & Stenhammar, J. (2023). Electrostatic interactions control the adsorption of extracellular vesicles onto supported lipid bilayers. Journal of Colloid and Interface Science, 650(Pt A), 883-891. https://doi.org/10.1016/j.jcis.2023.07.018
Giovanazzi, A., van Herwijnen, M. J. C., Kleinjan, M., van der Meulen, G. N., & Wauben, M. H. M. (2023). Surface protein profiling of milk and serum extracellular vesicles unveils body fluid-specific signatures. Scientific Reports, 13(1), 1-13. Article 8758. https://doi.org/10.1038/s41598-023-35799-w
Ridolfi, A., Cardellini, J., Gashi, F., Herwijnen, M. J. C. V., Trulsson, M., Campos-Terán, J., Wauben, M. H. M., Berti, D., Nylander, T., & Stenhammar, J. (2023). Electrostatic interactions control the adsorption of extracellular vesicles onto supported lipid bilayers. bioRxiv. https://doi.org/10.1101/2023.04.14.536633
2022
Scholarly publications
Giovanazzi, A., Herwijnen, M. J. C. V., Meulen, G. N. V. D., & Wauben, M. H. M. (2022). Surface protein profiling of milk and serum extracellular vesicles unveil body fluid and cell-type signatures and insights on vesicle biogenesis. (pp. 1-28). bioRxiv. https://doi.org/10.1101/2022.10.24.513472
Karra, N., Herwijnen, M. J. C. V., Wauben, M. H. M., Swindle, E. J., & Morgan, H. (2022). Human milk extracellular vesicles preserve bronchial epithelial barrier integrity and reduce TLR3‐induced inflammation in vitro. Journal of Extracellular Biology, 1(9), 1-9. Article e54. https://doi.org/10.1002/jex2.54
van der Grein, S. G., Defourny, K. A. Y., Rabouw, H. H., Goerdayal, S. S., van Herwijnen, M. J. C., Wubbolts, R. W., Altelaar, M., van Kuppeveld, F. J. M., & Nolte-'t Hoen, E. N. M. (2022). The encephalomyocarditis virus Leader promotes the release of virions inside extracellular vesicles via the induction of secretory autophagy. Nature Communications, 13(1), 1-14. Article 3625. https://doi.org/10.1038/s41467-022-31181-y
PRIMA Initiative Group (2022). Analysing the protection from respiratory tract infections and allergic diseases early in life by human milk components: the PRIMA birth cohort. BMC Infectious Diseases, 22(1), 1-10. Article 152. https://doi.org/10.1186/s12879-022-07107-w
2021
Scholarly publications
Zendrini, A., Paolini, L., Busatto, S., Radeghieri, A., Romano, M., Wauben, M. H. M., van Herwijnen, M. J. C., Nejsum, P., Borup, A., Ridolfi, A., Montis, C., & Bergese, P. (2021). Corrigendum: Augmented COlorimetric NANoplasmonic (CONAN) Method for Grading Purity and Determine Concentration of EV Microliter Volume Solutions. Frontiers in Bioengineering and Biotechnology, 9, 1-2. Article 674507. https://doi.org/10.3389/fbioe.2021.674507
Kleinjan, M., van Herwijnen, M. J., Libregts, S. F., van Neerven, R. J., Feitsma, A. L., & Wauben, M. H. (2021). Regular Industrial Processing of Bovine Milk Impacts the Integrity and Molecular Composition of Extracellular Vesicles. Journal of Nutrition, 151(6), 1416-1425. https://doi.org/10.1093/jn/nxab031
Zonneveld, M. I., van Herwijnen, M. J. C., Fernandez-Gutierrez, M. M., Giovanazzi, A., de Groot, A. M., Kleinjan, M., van Capel, T. M. M., Sijts, A. J. A. M., Taams, L. S., Garssen, J., de Jong, E. C., Kleerebezem, M., Nolte-'t Hoen, E. N. M., Redegeld, F. A., & Wauben, M. H. M. (2021). Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses. Journal of Extracellular Vesicles, 10(5), 1-17. Article e12071. https://doi.org/10.1002/jev2.12071
2020
Scholarly publications
Zonneveld, M. I., van Herwijnen, M. J. C., Fernandez-Gutierrez, M., Giovanazzi, A., de Groot, A. M., Kleinjan, M., van Capel, T. M., Sijts, E. J. A. M., Taams, L. S., Garssen, J., de Jong, E., Kleerebezem, M., t Hoen, E. N. M., Redegeld, F. A. M., & Wauben, M. H. M. (2020). Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses. (bioRxiv). https://doi.org/10.1101/2020.04.29.068841
Ridolfi, A., Brucale, M., Montis, C., Caselli, L., Paolini, L., Borup, A., Boysen, A. T., Loria, F., van Herwijnen, M. J. C., Kleinjan, M., Nejsum, P., Zarovni, N., Wauben, M. H. M., Berti, D., Bergese, P., & Valle, F. (2020). AFM-Based High-Throughput Nanomechanical Screening of Single Extracellular Vesicles. Analytical Chemistry, 92, 10274–10282. Article 15. https://doi.org/10.1021/acs.analchem.9b05716
Zendrini, A., Paolini, L., Busatto, S., Radeghieri, A., Romano, M., Wauben, M. H. M., van Herwijnen, M. J. C., Nejsum, P., Borup, A., Ridolfi, A., Montis, C., & Bergese, P. (2020). Augmented COlorimetric NANoplasmonic (CONAN) Method for Grading Purity and Determine Concentration of EV Microliter Volume Solutions. Frontiers in Bioengineering and Biotechnology, 7, Article 452. https://doi.org/10.3389/fbioe.2019.00452
2018
Scholarly publications
Théry, C., Witwer, K. W., Aikawa, E., Alcaraz, M. J., Anderson, J. D., Andriantsitohaina, R., Antoniou, A., Arab, T., Archer, F., Atkin-Smith, G. K., Ayre, D. C., Bach, J-M., Bachurski, D., Baharvand, H., Balaj, L., Baldacchino, S., Bauer, N. N., Baxter, A. A., Bebawy, M., ... Zuba-Surma, E. K. (2018). Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. Journal of Extracellular Vesicles, 7(1), Article 1535750. https://doi.org/10.1080/20013078.2018.1535750
van Herwijnen, M. J. C., Driedonks, T. A. P., Snoek, B. L., Kroon, A. M. T., Kleinjan, M., Jorritsma, R., Pieterse, C. M. J., Hoen, E. N. M. N., & Wauben, M. H. M. (2018). Abundantly present miRNAs in milk-derived extracellular vesicles are conserved between mammals. Frontiers in Nutrition, 5, Article 81. https://doi.org/10.3389/fnut.2018.00081
2017
Scholarly publications
Pathan, M., Keerthikumar, S., Chisanga, D., Alessandro, R., Ang, C-S., Askenase, P., Batagov, A. O., Benito-Martin, A., Camussi, G., Clayton, A., Collino, F., Di Vizio, D., Falcon-Perez, J. M., Fonseca, P., Fonseka, P., Fontana, S., Gho, Y. S., Hendrix, A., Hoen, E. N. M. N. T., ... Mathivanan, S. (2017). A novel community driven software for functional enrichment analysis of extracellular vesicles data. Journal of Extracellular Vesicles, 6(1), 1321455. https://doi.org/10.1080/20013078.2017.1321455
Van Deun, J., Mestdagh, P., Agostinis, P., Akay, Ö., Anand, S., Anckaert, J., Martinez, Z. A., Baetens, T., Beghein, E., Bertier, L., Berx, G., Boere, J., Boukouris, S., Bremer, M., Buschmann, D., Byrd, J. B., Casert, C., Cheng, L., Cmoch, A., ... t Hoen, E. N. M. (2017). EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research. Nature Methods, 14(3), 228-232. https://doi.org/10.1038/nmeth.4185
2016
Scholarly publications
Zonneveld, M. I., Van Herwijnen, M. J. C., Kleinjan, M., De Groot, M., Fernandez-Gutierrez, M., Sijts, A., Kleerebezem, M., Taams, L. S., Garssen, J., T'-Hoen, E. N. M., Redegeld, F. A., & Wauben, M. H. M. (2016). Breast milk-derived extracellular vesicles influence the development of the epithelial and immunological gastrointestinal barrier. Journal of Extracellular Vesicles, 5, 139. https://doi.org/10.3402/jev.v5.31552
Jansen, M. A. A., Van Herwijnen, M. J. C., Van Kooten, P. J. S., Hoek, A., Van Der Zee, R., Van Eden, W., & Broere, F. (2016). Generation of the first TCR transgenic mouse with CD4+ T cells recognizing an anti-inflammatory regulatory T cell-inducing Hsp70 peptide. Frontiers in Immunology, 7, Article 90. https://doi.org/10.3389/fimmu.2016.00090
van Herwijnen, M. J. C., Zonneveld, M. I., Goerdayal, S., Nolte-'t Hoen, E. N. M., Garssen, J., Stahl, B., Altelaar, A. F. M., Redegeld, F. A., & Wauben, M. H. M. (2016). Comprehensive proteomic analysis of human milk-derived extracellular vesicles unveils a novel functional proteome distinct from other milk components. Molecular & Cellular Proteomics, 15(11), 3412-3423. https://doi.org/10.1074/mcp.M116.060426
2015
Scholarly publications
Zonneveld, M., Van Herwijnen, M., Brouwers, J., Garssen, J., Redegeld, F., Nolte-'t Hoen, E., & Wauben, M. (2015). Defined breast milk EV subsets boost the immune response and skew the T-cell balance towards a regulatory phenotype. Journal of Extracellular Vesicles, 4, 28. https://doi.org/10.3402/jev.v4.27783
Van Herwijnen, M., Zonneveld, M., Goerdayal, S., Altelaar, M., Hoen, E. N., Garssen, J., Redegeld, F., & Wauben, M. (2015). In-depth proteomics analysis of human breast milk-derived extracellular vesicles to reveal their origin and targets in the infant's developing immune system. Journal of Extracellular Vesicles, 4, 81. https://doi.org/10.3402/jev.v4.27783
Delemarre, E. M., van den Broek, T., Mijnheer, G., Meerding, J., Wehrens, E. J., Olek, S., Boes, M., van Herwijnen, M. J. C., Broere, F., van Royen, A., Wulffraat, N. M., Prakken, B. J., Spierings, E., & van Wijk, F. (2015). Autologous stem cell transplantation benefits autoimmune patients through functional renewal and TCR diversification of the regulatory T cell compartment. Blood. https://doi.org/10.1182/blood-2015-06-649145
van Herwijnen, M. J. C., van der Zee, R., van Eden, W., & Broere, F. (2015). In Vivo Induction of Functionally Suppressive Induced Regulatory T Cells from CD4+CD25- T Cells Using an Hsp70 Peptide. PLoS One, 10(6), Article e0128373. https://doi.org/10.1371/journal.pone.0128373
2014
Scholarly publications
Zonneveld, M. I., Brisson, A. R., van Herwijnen, M. J. C., Tan, S., van de Lest, C. H. A., Redegeld, F. A., Garssen, J., Wauben, M. H. M., & Nolte - t Hoen, E. (2014). Recovery of extracellular vesicles from human breast milk is influenced by sample collection and vesicle isolation procedures. Journal of Extracellular Vesicles, 3. https://doi.org/10.3402/jev.v3.24215
2013
Scholarly publications
van Eden, W., van Herwijnen, M. J. C., Wagenaar, J., van Kooten, P., Broere, F., & van der Zee, R. (2013). Stress proteins are used by the immune system for cognate interactions with anti-inflammatory regulatory T cells. FEBS Letters, 587, 1951-1958. https://doi.org/10.1016/j.febslet.2013.05.024
van Herwijnen, M. J. C., van der Zee, R., van Eden, W., & Broere, F. (2013). Heat shock proteins can be targets of regulatory T cells for therapeutic intervention in rheumatoid arthritis. International Journal of Hyperthermia, 29, 448-454. https://doi.org/10.3109/02656736.2013.811546
van Herwijnen, M. J. C. (2013). Heat shock proteins are targets of regulatory T cells. [Doctoral thesis 1 (Research UU / Graduation UU), Utrecht University]. Utrecht University.
https://dspace.library.uu.nl/bitstream/handle/1874/287137/herwijnen.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/287137/herwijnen.pdf?sequence=1
2012
Scholarly publications
Keijzer, C., Wieten, L., van Herwijnen, M. J. C., van der Zee, R., van Eden, W., & Broere, F. (2012). Heat shock proteins are therapeutic targets in autoimmune diseases and other chronic inflammatory conditions. Expert Opinion on Therapeutic Targets, 16(9), 849-857. https://doi.org/10.1517/14728222.2012.706605
Borges, T. J., Wieten, L., van Herwijnen, M. J. C., Broere, F., van der Zee, R., Bonorino, C., & van Eden, W. (2012). The anti-inflammatory mechanisms of Hsp70. Frontiers in Immunology [E], 3, 10.3389/fimmu.2012.00095. Article 95. https://doi.org/10.3389/fimmu.2012.00095
van Herwijnen, M. J. C., Wieten, L., van der Zee, R., van Kooten, P. J., Wagenaar, J. P. A., Hoek, A., den Braber, A. J., Anderton, S. M., Singh, M., Meiring, H. D., van Els, C. A. C. M., van Eden, W., & Broere, F. (2012). Regulatory T cells that recognize a ubiquitous stress-inducible self-antigen are long-lived suppressors of autoimmune arthritis. Proceedings of the National Academy of Sciences of the United States of America, 109(35), 14134-14139. https://doi.org/10.1073/pnas.1206803109