Publications
2023
Scholarly publications
Truong, M. A., Cané-Gasull, P., de Vries, S. G., Nijenhuis, W., Wardenaar, R., Kapitein, L. C., Foijer, F., & Lens, S. (2023). A kinesin-based approach for inducing chromosome-specific mis-segregation in human cells. EMBO Journal, 42(10), [e111559]. https://doi.org/10.15252/embj.2022111559
2022
Scholarly publications
Jager, L. D., Jansen, K. I., Kapitein, L. C., Förster, F., & Howes, S. C. (2022). Increased microtubule lattice spacing correlates with selective binding of kinesin-1 in cells. (pp. 1-24). bioRxiv. https://doi.org/10.1101/2022.05.25.493428
Hung, S-T., Cnossen, J., Fan, D., Siemons, M., Jurriens, D., Grußmayer, K., Soloviev, O., Kapitein, L. C., & Smith, C. S. (2022). Soleil: single-objective lens inclined light sheet localization microscopy. Biomedical Optics Express, 13(6), 3275-3294. https://doi.org/10.1364/BOE.451634
Amatngalim, G. D., Rodenburg, L. W., Aalbers, B. L., Raeven, H. H., Aarts, E. M., Sarhane, D., Spelier, S., Lefferts, J. W., Silva, I. A., Nijenhuis, W., Vrendenbarg, S., Kruisselbrink, E., Brunsveld, J. E., van Drunen, C. M., Michel, S., de Winter-de Groot, K. M., Heijerman, H. G., Kapitein, L. C., Amaral, M. D., ... Beekman, J. M. (2022). Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia. Life Science Alliance, 5(12), 1-14. [e202101320]. https://doi.org/10.26508/lsa.202101320
Hung, S-T., Llobet Rosell, A., Jurriens, D., Siemons, M., Soloviev, O., Kapitein, L. C., Grußmayer, K., Neukomm, L. J., Verhaegen, M., & Smith, C. (2022). Adaptive optics in single objective inclined light sheet microscopy enables three-dimensional localization microscopy in adult Drosophila brains. Frontiers in Neuroscience, 16, 1-21. [954949]. https://doi.org/10.3389/fnins.2022.954949
Siemons, M. E., Kapitein, L. C., & Stallinga, S. (2022). Axial accuracy in localization microscopy with 3D point spread function engineering. Optics Express, 30(16), 28290-28300. https://doi.org/10.1364/OE.461750
Burute, M., Jansen, K. I., Mihajlovic, M., Vermonden, T., & Kapitein, L. C. (2022). Local changes in microtubule network mobility instruct neuronal polarization and axon specification. Science advances, 8(44), 1-11. [eabo2343]. https://doi.org/10.1126/sciadv.abo2343
Damstra, H. G. J., Mohar, B., Eddison, M., Akhmanova, A., Kapitein, L. C., & Tillberg, P. W. (2022). Correction: Visualizing cellular and tissue ultrastructure using Ten-fold Robust Expansion Microscopy (TREx). eLife, 11. https://doi.org/10.7554/eLife.85169
Damstra, H. G. J., Mohar, B., Eddison, M., Akhmanova, A., Kapitein, L. C., & Tillberg, P. W. (2022). Visualizing cellular and tissue ultrastructure using Ten-fold Robust Expansion Microscopy (TREx). eLife, 11, 1-24. [e73775]. https://doi.org/10.7554/ELIFE.73775
Akhmanova, A., & Kapitein, L. C. (2022). Mechanisms of microtubule organization in differentiated animal cells. Nature Reviews Molecular Cell Biology, 23(8), 541-558. https://doi.org/10.1038/s41580-022-00473-y
https://dspace.library.uu.nl/bitstream/handle/1874/423820/s41580_022_00473_y.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/423820/s41580_022_00473_y.pdf?sequence=1
Meiring, J. C. M., Grigoriev, I., Nijenhuis, W., Kapitein, L. C., & Akhmanova, A. (2022). Opto-katanin, an optogenetic tool for localized, microtubule disassembly. Current Biology, 32(21), 4660-4674.e6. https://doi.org/10.1016/j.cub.2022.09.010
Chen, F., Wu, J., Iwanski, M. K., Jurriens, D., Sandron, A., Pasolli, M., Puma, G., Kromhout, J. Z., Yang, C., Nijenhuis, W., Kapitein, L. C., Berger, F., & Akhmanova, A. (2022). Self-assembly of pericentriolar material in interphase cells lacking centrioles. eLife, 11, 1-47. [e77892]. https://doi.org/10.7554/eLife.77892
Noordstra, I., van den Berg, C. M., Boot, F. W. J., Katrukha, E. A., Yu, K. L., Tas, R. P., Portegies, S., Viergever, B. J., de Graaff, E., Hoogenraad, C. C., de Koning, E. J. P., Carlotti, F., Kapitein, L. C., & Akhmanova, A. (2022). Organization and dynamics of the cortical complexes controlling insulin secretion in β-cells. Journal of Cell Science, 135(3), 1-18. [jcs259430]. https://doi.org/10.1242/jcs.259430
Karst, H., den Boon, F. S., Vervoort, N., Adrian, M., Kapitein, L. C., & Joëls, M. (2022). Non-genomic steroid signaling through the mineralocorticoid receptor: Involvement of a membrane-associated receptor? Molecular and Cellular Endocrinology, 541, 1-11. [111501]. https://doi.org/10.1016/j.mce.2021.111501
Fu, D., Maris, J. J. E., Stanciakova, K., Nikolopoulos, N., van der Heijden, O., Mandemaker, L. D. B., Siemons, M. E., Pastene, D. S., Kapitein, L. C., Rabouw, F. T., Meirer, F., & Weckhuysen, B. M. (2022). Unravelling Channel Structure-Diffusivity Relationships in Zeolite ZSM-5 at the Single-Molecule Level. Angewandte Chemie-International Edition, 61(5), 1-5. [e202114388]. https://doi.org/10.1002/anie.202114388
2021
Scholarly publications
Katrukha, E. A., Jurriens, D., Salas Pastene, D. M., & Kapitein, L. C. (2021). Quantitative mapping of dense microtubule arrays in mammalian neurons. eLife, 10, 1-25. [10:e67925]. https://doi.org/10.7554/eLife.67925
Siemons, M. E., Hanemaaijer, N. A. K., Kole, M. H. P., & Kapitein, L. C. (2021). Robust adaptive optics for localization microscopy deep in complex tissue. Nature Communications, 12(1), 1-9. [3407]. https://doi.org/10.1038/s41467-021-23647-2
Rai, A., Liu, T., Katrukha, E. A., Estévez-Gallego, J., Manka, S. W., Paterson, I., Díaz, J. F., Kapitein, L. C., Moores, C. A., & Akhmanova, A. (2021). Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes. Proceedings of the National Academy of Sciences of the United States of America, 118(51), 1-11. [e2112261118]. https://doi.org/10.1073/pnas.2112261118
Janssen, A. F. J., Korsten, G., Nijenhuis, W., Katrukha, E. A., & Kapitein, L. C. (2021). Direct observation of aggregate-triggered selective autophagy in human cells. Journal of Cell Science, 134(19), 1-11. [jcs258824]. https://doi.org/10.1242/jcs.258824
Gros, O. J., Damstra, H. G. J., Kapitein, L. C., Akhmanova, A., & Berger, F. (2021). Dynein self-organizes while translocating the centrosome in T-cells. Molecular Biology of the Cell, 32(9), 855-868. https://doi.org/10.1091/MBC.E20-10-0668
Buijs, R. R., Hummel, J. J. A., Burute, M., Pan, X., Cao, Y., Stucchi, R., Altelaar, M., Akhmanova, A., Kapitein, L. C., & Hoogenraad, C. C. (2021). WDR47 protects neuronal microtubule minus ends from katanin-mediated severing. Cell Reports, 36(2), 1-e7. [109371]. https://doi.org/10.1016/j.celrep.2021.109371
Özkan, N., Koppers, M., van Soest, I., van Harten, A., Jurriens, D., Liv, N., Klumperman, J., Kapitein, L. C., Hoogenraad, C. C., & Farías, G. G. (2021). ER - lysosome contacts at a pre-axonal region regulate axonal lysosome availability. Nature Communications, 12(1), [4493]. https://doi.org/10.1038/s41467-021-24713-5
Filez, M., Vesely, M., Garcia-Torregrosa, I., Gambino, M., Attila, Ö., Meirer, F., Katrukha, E. A., Roeffaers, M. B. J., Garrevoet, J., Kapitein, L. C., & Weckhuysen, B. M. (2021). Chemical Imaging of Hierarchical Porosity Formation within a Zeolite Crystal Visualized by Small-Angle X-Ray Scattering and In-Situ Fluorescence Microscopy. Angewandte Chemie - International Edition, 60(25), 13803-13806. https://doi.org/10.1002/anie.202101747
Passmore, J. B., Nijenhuis, W., & Kapitein, L. C. (2021). From observing to controlling: Inducible control of organelle dynamics and interactions. Current Opinion in Cell Biology, 71, 69-76. https://doi.org/10.1016/j.ceb.2021.02.002
Gao, L., Meiring, J. C. M., Kraus, Y., Wranik, M., Weinert, T., Pritzl, S. D., Bingham, R., Ntouliou, E., Jansen, K. I., Olieric, N., Standfuss, J., Kapitein, L. C., Lohmüller, T., Ahlfeld, J., Akhmanova, A., Steinmetz, M. O., & Thorn-Seshold, O. (2021). A Robust, GFP-Orthogonal Photoswitchable Inhibitor Scaffold Extends Optical Control over the Microtubule Cytoskeleton. Cell Chemical Biology, 28(2), 228-241.e6. https://doi.org/10.1016/j.chembiol.2020.11.007
https://dspace.library.uu.nl/bitstream/handle/1874/410295/PIIS2451945620304700.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/410295/PIIS2451945620304700.pdf?sequence=1
2020
Scholarly publications
Hooikaas, P. J., Damstra, H. GJ., Gros, O. J., Riel, W. E. V., Martin, M., Smits, Y. TH., Loosdregt, J. V., Kapitein, L. C., Berger, F., & Akhmanova, A. (2020). Kinesin-4 KIF21B limits microtubule growth to allow rapid centrosome polarization in T cells. eLife, 9, 1-41. [62876]. https://doi.org/10.7554/eLife.62876
Lu, M., van Tartwijk, F. W., Lin, J. Q., Nijenhuis, W., Parutto, P., Fantham, M., Christensen, C. N., Avezov, E., Holt, C. E., Tunnacliffe, A., Holcman, D., Kapitein, L., Schierle, G. S. K., & Kaminski, C. F. (2020). The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes. Science advances, 6(51), [eabc7209]. https://doi.org/10.1126/sciadv.abc7209
Rodríguez-García, R., Volkov, V. A., Chen, C-Y., Katrukha, E. A., Olieric, N., Aher, A., Grigoriev, I., López, M. P., Steinmetz, M. O., Kapitein, L. C., Koenderink, G., Dogterom, M., & Akhmanova, A. (2020). Mechanisms of Motor-Independent Membrane Remodeling Driven by Dynamic Microtubules. Current Biology, 30(6), 972-987. [e12]. https://doi.org/10.1016/j.cub.2020.01.036
Serra-Marques, A., Martin, M., Katrukha, E. A., Grigoriev, I., Peeters, C. A. E., Liu, Q., Hooikaas, P. J., Yao, Y., Solianova, V., Smal, I., Pedersen, L. B., Meijering, E., Kapitein, L. C., & Akhmanova, A. (2020). Concerted action of kinesins KIF5B and KIF13B promotes efficient secretory vesicle transport to microtubule plus ends. eLife, 9, [e61302]. https://doi.org/10.7554/eLife.61302
Müller-Deku, A., Meiring, J. C. M., Loy, K., Kraus, Y., Heise, C., Bingham, R., Jansen, K. I., Qu, X., Bartolini, F., Kapitein, L. C., Akhmanova, A., Ahlfeld, J., Trauner, D., & Thorn-Seshold, O. (2020). Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton. Nature Communications, 11, [4640]. https://doi.org/10.1038/s41467-020-18389-6
Cao, Y., Lipka, J., Stucchi, R., Burute, M., Pan, X., Portegies, S., Tas, R., Willems, J., Will, L., MacGillavry, H., Altelaar, M., Kapitein, L. C., Harterink, M., & Hoogenraad, C. C. (2020). Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule Organization. Current Biology, 30(5), 899-908.e6. https://doi.org/10.1016/j.cub.2019.12.056
Siemons, M., Cloin, B. M. C., Salas, D. M., Nijenhuis, W., Katrukha, E. A., & Kapitein, L. C. (2020). Comparing strategies for deep astigmatism-based single-molecule localization microscopy. Biomedical Optics Express, 11(2), 735-751. https://doi.org/10.1364/BOE.382023
Nijenhuis, W., van Grinsven, M. M. P., & Kapitein, L. C. (2020). An optimized toolbox for the optogenetic control of intracellular transport. Journal of Cell Biology, 219(4), [e201907149]. https://doi.org/10.1083/jcb.201907149
Rai, A., Liu, T., Glauser, S., Katrukha, E. A., Estévez-Gallego, J., Rodríguez-García, R., Fang, W-S., Díaz, J. F., Steinmetz, M. O., Altmann, K-H., Kapitein, L. C., Moores, C. A., & Akhmanova, A. (2020). Taxanes convert regions of perturbed microtubule growth into rescue sites. Nature Materials, 19(3), 1-11. https://doi.org/10.1038/s41563-019-0546-6
https://dspace.library.uu.nl/bitstream/handle/1874/395497/s41563_019_0546_6.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/395497/s41563_019_0546_6.pdf?sequence=1
2019
Scholarly publications
Burute, M., & Kapitein, L. C. (2019). Cellular logistics: Unraveling the interplay between microtubule organization and intracellular transport. Annual Review of Cell and Developmental Biology, 35, 29-54. https://doi.org/10.1146/annurev-cellbio-100818-125149
https://dspace.library.uu.nl/bitstream/handle/1874/389887/burute.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/389887/burute.pdf?sequence=1
Stanganello, E., Zahavi, E. E., Burute, M., Smits, J., Jordens, I., Maurice, M. M., Kapitein, L. C., & Hoogenraad, C. C. (2019). Wnt Signaling Directs Neuronal Polarity and Axonal Growth. iScience, 13, 318-327. https://doi.org/10.1016/j.isci.2019.02.029
Harterink, M., Vocking, K., Pan, X., Soriano Jerez, E. M., Slenders, L., Fréal, A., Tas, R. P., Van De Wetering, W. J., Timmer, K., Motshagen, J., Van Beuningen, S. F. B., Kapitein, L. C., Geerts, W. J. C., Post, J. A., & Hoogenraad, C. C. (2019). TRIM46 Organizes Microtubule Fasciculation in the Axon Initial Segment. Journal of Neuroscience, 39(25), 4864-4873. https://doi.org/10.1523/JNEUROSCI.3105-18.2019
https://dspace.library.uu.nl/bitstream/handle/1874/388379/4864.full.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/388379/4864.full.pdf?sequence=1
Fréal, A., Rai, D., Tas, R. P., Pan, X., Katrukha, E. A., van de Willige, D., Stucchi, R., Aher, A., Yang, C., Altelaar, A. F. M., Vocking, K., Post, J. A., Harterink, M., Kapitein, L. C., Akhmanova, A., & Hoogenraad, C. C. (2019). Feedback-Driven Assembly of the Axon Initial Segment. Neuron, 104(2), P305-321.E8. https://doi.org/10.1016/j.neuron.2019.07.029
Hooikaas, P. J., Martin, M., Mühlethaler, T., Kuijntjes, G. J., Peeters, C. A. E., Katrukha, E. A., Ferrari, L., Stucchi, R., Verhagen, D. G. F., Van Riel, W. E., Grigoriev, I., Altelaar, A. F. M., Hoogenraad, C. C., Rüdiger, S. G. D., Steinmetz, M. O., Kapitein, L. C., & Akhmanova, A. (2019). MAP7 family proteins regulate kinesin-1 recruitment and activation. Journal of Cell Biology, 218(4), 1298-1318. https://doi.org/10.1083/jcb.201808065
2018
Scholarly publications
Tas, R. P., & Kapitein, L. C. (2018). Exploring cytoskeletal diversity in neurons. Science, 361(6399), 231-232. https://doi.org/10.1126/science.aat5992
https://dspace.library.uu.nl/bitstream/handle/1874/375444/cytoskeletal.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/375444/cytoskeletal.pdf?sequence=1
Janssen, A. F. J., Katrukha, E. A., van Straaten, W., Verlhac, P., Reggiori, F., & Kapitein, L. C. (2018). Probing aggrephagy using chemically-induced protein aggregates. Nature Communications, 9, [4245]. https://doi.org/10.1038/s41467-018-06674-4
Tas, R. P., Chen, C-Y., Katrukha, E. A., Vleugel, M., Kok, M., Dogterom, M., Akhmanova, A., & Kapitein, L. C. (2018). Guided by Light: Optical Control of Microtubule Gliding Assays. Nano Letters, 18, 7524-7528. https://doi.org/10.1021/acs.nanolett.8b03011
Aher, A., Kok, M., Sharma, A., Rai, A., Olieric, N., Rodriguez-Garcia, R., Katrukha, E. A., Weinert, T., Olieric, V., Kapitein, L. C., Steinmetz, M. O., Dogterom, M., & Akhmanova, A. (2018). CLASP Suppresses Microtubule Catastrophes through a Single TOG Domain. Developmental Cell, 46(1), 40-58.e8. https://doi.org/10.1016/j.devcel.2018.05.032
Kahn, O. I., Schätzle, P., van de Willige, D., Tas, R. P., Lindhout, F. W., Portegies, S., Kapitein, L. C., & Hoogenraad, C. C. (2018). APC2 controls dendrite development by promoting microtubule dynamics. Nature Communications, 9, [2773]. https://doi.org/10.1038/s41467-018-05124-5
Harterink, M., Edwards, S. L., de Haan, B., Yau, K. W., van den Heuvel, S., Kapitein, L. C., Miller, K. G., & Hoogenraad, C. C. (2018). Local microtubule organization promotes cargo transport in C. elegans dendrites. Journal of Cell Science, 131(20), [ jcs223107]. https://doi.org/10.1242/jcs.223107
Cunha-Ferreira, I., Chazeau, A., Buijs, R. R., Stucchi, R., Will, L., Pan, X., Adolfs, Y., van der Meer, C., Wolthuis, J. C., Kahn, O. I., Schätzle, P., Altelaar, M., Pasterkamp, R. J., Kapitein, L. C., & Hoogenraad, C. C. (2018). The HAUS Complex Is a Key Regulator of Non-centrosomal Microtubule Organization during Neuronal Development. Cell Reports, 24(4), 791-800. https://doi.org/10.1016/j.celrep.2018.06.093
Schätzle, P., Esteves da Silva, M., Tas, R. P., Katrukha, E. A., Hu, H. Y., Wierenga, C. J., Kapitein, L. C., & Hoogenraad, C. C. (2018). Activity-Dependent Actin Remodeling at the Base of Dendritic Spines Promotes Microtubule Entry. Current Biology, 28(13), 2081-2093.e6. https://doi.org/10.1016/j.cub.2018.05.004
Sun, F., Adrian, M., Beztsinna, N., van den Dikkenberg, J. B., Maas-Bakker, R. F., van Hasselt, P. M., van Steenbergen, M. J., Su, X., Kapitein, L. C., Hennink, W. E., & van Nostrum, C. F. (2018). Influence of PEGylation of vitamin-K-loaded mixed micelles on the uptake by and transport through Caco-2 cells. Molecular Pharmaceutics, 15(9), 3786–3795. https://doi.org/10.1021/acs.molpharmaceut.8b00258
Tas, R. P., Bos, T. G. A. A., & Kapitein, L. C. (2018). Purification and Application of a Small Actin Probe for Single-Molecule Localization Microscopy. In E. J. G. Peterman (Ed.), Single Molecule Analysis: Methods and Protocols (pp. 155-171). (Methods in Molecular Biology; Vol. 1665). Humana Press. https://doi.org/10.1007/978-1-4939-7271-5_9
https://dspace.library.uu.nl/bitstream/handle/1874/362886/Purification.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/362886/Purification.pdf?sequence=1
2017
Scholarly publications
Adrian, M., Nijenhuis, W., Hoogstraaten, R. I., Willems, J., & Kapitein, L. C. (2017). A Phytochrome-Derived Photoswitch for Intracellular Transport. ACS Synthetic Biology, 6(7), 1248-1256. https://doi.org/10.1021/acssynbio.6b00333
Adrian, M., Kusters, R., Storm, C., Hoogenraad, C. C., & Kapitein, L. C. (2017). Probing the Interplay between Dendritic Spine Morphology and Membrane-Bound Diffusion. Biophysical Journal, 113(10), 2261-2270. https://doi.org/10.1016/j.bpj.2017.06.048
Janssen, A. F. J., Tas, R. P., van Bergeijk, P., Oost, R., Hoogenraad, C. C., & Kapitein, L. C. (2017). Myosin-V Induces Cargo Immobilization and Clustering at the Axon Initial Segment. Frontiers in Cellular Neuroscience, 11, [260]. https://doi.org/10.3389/fncel.2017.00260
Tas, R. P., Chazeau, A., Cloin, B. M. C., Lambers, M. L. A., Hoogenraad, C. C., & Kapitein, L. C. (2017). Differentiation between Oppositely Oriented Microtubules Controls Polarized Neuronal Transport. Neuron, 96(6), 1264-1271. https://doi.org/10.1016/j.neuron.2017.11.018
Katrukha, E. A., Mikhaylova, M., van Brakel, H. X., van Bergen En Henegouwen, P. M., Akhmanova, A., Hoogenraad, C. C., & Kapitein, L. C. (2017). Probing cytoskeletal modulation of passive and active intracellular dynamics using nanobody-functionalized quantum dots. Nature Communications, 8, [14772]. https://doi.org/10.1038/ncomms14772
Harterink, M., Santos Esteves da Silva, M., Will, L., Turan, J., Ibrahim, A., Lang, A. E., Van Battum, E. Y., Pasterkamp, R. J., Kapitein, L. C., Kudryashov, D., Barres, B. A., Hoogenraad, C. C., & Zuchero, J. B. (2017). DeActs: genetically encoded tools for perturbing the actin cytoskeleton in single cells. Nature Methods, 14(5), 479-482. https://doi.org/10.1038/nmeth.4257
https://dspace.library.uu.nl/bitstream/handle/1874/359001/deacts.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/359001/deacts.pdf?sequence=1
Gumy, L. F., Katrukha, E. A., Grigoriev, I., Jaarsma, D., Kapitein, L. C., Akhmanova, A., & Hoogenraad, C. C. (2017). MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus KIF5-Dependent Cargo Transport in Sensory Neurons. Neuron, 94(2), 347-362.e7. https://doi.org/10.1016/j.neuron.2017.03.046
https://dspace.library.uu.nl/bitstream/handle/1874/359343/1_s2.0_S0896627317302908_main.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/359343/1_s2.0_S0896627317302908_main.pdf?sequence=1
Tortosa Binacua, E., Adolfs, Y., Fukata, M., Pasterkamp, R. J., Kapitein, L. C., & Hoogenraad, C. C. (2017). Dynamic Palmitoylation Targets MAP6 to the Axon to Promote Microtubule Stabilization during Neuronal Polarization. Neuron, 94(4), 809-825.e7. https://doi.org/10.1016/j.neuron.2017.04.042
Cloin, B. M. C., De Zitter, E., Salas Pastene, D., Gielen, V., Folkers, G. E., Mikhaylova, M., Bergeler, M., Krajnik, B., Harvey, J., Hoogenraad, C. C., Van Meervelt, L., Dedecker, P., & Kapitein, L. C. (2017). Efficient switching of mCherry fluorescence using chemical caging. Proceedings of the National Academy of Sciences of the United States of America, 114(27), 7013-7018. https://doi.org/10.1073/pnas.1617280114
van Riel, W. E., Rai, A., Bianchi, S., Katrukha, E. A., Liu, Q., Heck, A. J., Hoogenraad, C. C., Steinmetz, M. O., Kapitein, L. C., & Akhmanova, A. (2017). Kinesin-4 KIF21B is a potent microtubule pausing factor. eLife, 6, [e24746]. https://doi.org/10.7554/eLife.24746
2016
Scholarly publications
Tortosa Binacua, E., Kapitein, L. C., & Hoogenraad, C. C. (2016). Microtubule Organization and Microtubule-Associated Proteins (MAPs). In K. Emoto, R. Wong, E. Huang, & C. Hoogenraad (Eds.), Dendrites: Development and Disease (pp. 31). Springer. https://doi.org/10.1007/978-4-431-56050-0_3
Doodhi, H., Prota, A. E., Rodríguez-García, R., Xiao, H., Custar, D. W., Bargsten, K., Katrukha, E. A., Hilbert, M., Hua, S., Jiang, K., Grigoriev, I., Yang, C-P. H., Cox, D., Horwitz, S. B., Kapitein, L. C., Akhmanova, A., & Steinmetz, M. O. (2016). Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes. Current Biology, 26(13), 1713-1721. https://doi.org/10.1016/j.cub.2016.04.053
https://dspace.library.uu.nl/bitstream/handle/1874/344458/Termination.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/344458/Termination.pdf?sequence=1
Noordstra, I., Liu, Q., Nijenhuis, W., Hua, S., Jiang, K., Baars, M., Remmelzwaal, S., Martin, M., Kapitein, L., & Akhmanova, A. (2016). Control of apico-basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7. Journal of Cell Science, 129(22), 4278-4288. https://doi.org/10.1242/jcs.194878
Kaplan, M., Narasimhan, S., de Heus, C., Mance, D., van Doorn, S., Houben, K., Popov-Celeketic, D., Damman, R., Katrukha, E. A., Jain, P., Geerts, W. J. C., Heck, A. J. R., Folkers, G. E., Kapitein, L. C., Lemeer, S., van Bergen En Henegouwen, P. M. P., & Baldus, M. (2016). EGFR Dynamics Change during Activation in Native Membranes as Revealed by NMR. Cell, 167(5), 1241-1251.e11. https://doi.org/10.1016/j.cell.2016.10.038
Yau, K. W., Schätzle, P., Tortosa, E., Pagès, S., Holtmaat, A., Kapitein, L. C., & Hoogenraad, C. (2016). Dendrites In Vitro and In Vivo Contain Microtubules of Opposite Polarity and Axon Formation Correlates with Uniform Plus-End-Out Microtubule Orientation. Journal of Neuroscience, 36(4), 1071-85. https://doi.org/10.1523/JNEUROSCI.2430-15.2016
Chazeau, A., Katrukha, E. A., Hoogenraad, C. C., & Kapitein, L. C. (2016). Studying neuronal microtubule organization and microtubule-associated proteins using single molecule localization microscopy. Methods in Cell Biology, 131, 127-49. https://doi.org/10.1016/bs.mcb.2015.06.017
https://dspace.library.uu.nl/bitstream/handle/1874/343664/Studying.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/343664/Studying.pdf?sequence=1
Schätzle, P., Kapitein, L. C., & Hoogenraad, C. C. (2016). Live imaging of microtubule dynamics in organotypic hippocampal slice cultures. Methods in Cell Biology, 131, 107-126. https://doi.org/10.1016/bs.mcb.2015.06.006
https://dspace.library.uu.nl/bitstream/handle/1874/343663/Live.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/343663/Live.pdf?sequence=1
Lipka, J., Kapitein, L. C., Jaworski, J., & Hoogenraad, C. C. (2016). Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites. EMBO Journal, 35(3), 302-18. https://doi.org/10.15252/embj.201592929
https://dspace.library.uu.nl/bitstream/handle/1874/344421/protein.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/344421/protein.pdf?sequence=1
Kuijpers, M., van de Willige, D., Freal, A., Chazeau, A., Franker, M. A., Hofenk, J., Rodrigues, R. J. C., Kapitein, L. C., Akhmanova, A., Jaarsma, D., & Hoogenraad, C. C. (2016). Dynein Regulator NDEL1 Controls Polarized Cargo Transport at the Axon Initial Segment. Neuron, 89(3), 461-471. https://doi.org/10.1016/j.neuron.2016.01.022
https://dspace.library.uu.nl/bitstream/handle/1874/344420/Dynein.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/344420/Dynein.pdf?sequence=1
Harterink, M., van Bergeijk, P., Allier, C., de Haan, B., van den Heuvel, S., Hoogenraad, C. C., & Kapitein, L. C. (2016). Light-controlled intracellular transport in Caenorhabditis elegans. Current Biology, 26(4), PR153-R154. https://doi.org/10.1016/j.cub.2015.12.016
Kevenaar, J. T., Bianchi, S., van Spronsen, M., Olieric, N., Lipka, J., Frias, C. P., Mikhaylova, M., Harterink, M., Keijzer, N., Wulf, P. S., Hilbert, M., Kapitein, L. C., de Graaff, E., Akhmanova, A., Steinmetz, M. O., & Hoogenraad, C. C. (2016). Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity. Current Biology, 26(7), 849-861. https://doi.org/10.1016/j.cub.2016.01.048
https://dspace.library.uu.nl/bitstream/handle/1874/343660/Microtubule.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/343660/Microtubule.pdf?sequence=1
Franker, M. A., Esteves da Silva, M., Tas, R. P., Tortosa, E., Cao, Y., Frias, C. P., Janssen, A. F. J., Wulf, P. S., Kapitein, L. C., & Hoogenraad, C. C. (2016). Three-Step Model for Polarized Sorting of KIF17 into Dendrites. Current Biology, 26(13), 1705-1712. https://doi.org/10.1016/j.cub.2016.04.057
https://dspace.library.uu.nl/bitstream/handle/1874/341485/Model.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/341485/Model.pdf?sequence=1
Liu, Q., Liu, F., Yu, K. L., Tas, R., Grigoriev, I., Remmelzwaal, S., Marques, A., Kapitein, L. C., Heck, A. J. R., & Akhmanova, A. (2016). MICAL3 flavoprotein monooxygenase forms a complex with centralspindlin and regulates cytokinesis. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.M116.748186
van Bergeijk, P., Hoogenraad, C. C., & Kapitein, L. C. (2016). Right Time, Right Place: Probing the Functions of Organelle Positioning. Trends in Cell Biology, 26(2), 121-134. https://doi.org/10.1016/j.tcb.2015.10.001
https://dspace.library.uu.nl/bitstream/handle/1874/329577/Right.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/329577/Right.pdf?sequence=1
2015
Scholarly publications
Adrian, M., Hoogenraad, C. C., & Kapitein, L. C. (2015). Positioning of Rab11-positive recycling endosomes regulates synapse architecture and growth cone dynamics. Molecular Biology of the Cell, 26(25). https://doi.org/10.1091/mbc.E15-09-0674
van Beuningen, S. F. B., Will, L., Harterink, M., Chazeau, A., van Battum, E. Y., Frias, C. P., Franker, M. A. M., Katrukha, E. A., Stucchi, R., Vocking, K., Antunes, A. T., Slenders, L., Doulkeridou, S., Sillevis Smitt, P., Altelaar, A. F. M., Post, J. A., Akhmanova, A., Pasterkamp, R. J., Kapitein, L. C., ... Hoogenraad, C. C. (2015). TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays. Neuron, 88(6), 1208-1226. https://doi.org/10.1016/j.neuron.2015.11.012
Kapitein, L. C., & Hoogenraad, C. C. (2015). Building the Neuronal Microtubule Cytoskeleton. Neuron, 87(3), 492-506. https://doi.org/10.1016/j.neuron.2015.05.046
https://dspace.library.uu.nl/bitstream/handle/1874/329578/39_main.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/329578/39_main.pdf?sequence=1
Mikhaylova, M., Cloin, B. M. C., Finan, K., van den Berg, R., Teeuw, J., Kijanka, M. M., Sokolowski, M., Katrukha, E. A., Maidorn, M., Opazo, F., Moutel, S., Vantard, M., Perez, F., van Bergen en Henegouwen, P. M. P., Hoogenraad, C. C., Ewers, H., & Kapitein, L. C. (2015). Resolving bundled microtubules using anti-tubulin nanobodies. Nature Communications [E], 6, [7933]. https://doi.org/10.1038/ncomms8933
https://dspace.library.uu.nl/bitstream/handle/1874/324920/33.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/324920/33.pdf?sequence=1
Esteves da Silva, M., Adrian, M., Schätzle, P., Lipka, J., Watanabe, T., Cho, S., Futai, K., Wierenga, C. J., Kapitein, L. C., & Hoogenraad, C. C. (2015). Positioning of AMPA Receptor-Containing Endosomes Regulates Synapse Architecture. Cell Reports [E], 13(5), 933-943. https://doi.org/10.1016/j.celrep.2015.09.062
van Bergeijk, P., Adrian, M., Hoogenraad, C. C., & Kapitein, L. C. (2015). Optogenetic control of organelle transport and positioning. Nature, 518, 111–114 . https://doi.org/10.1038/nature14128
https://dspace.library.uu.nl/bitstream/handle/1874/320995/nature14128.pdf?sequence=2
https://dspace.library.uu.nl/bitstream/handle/1874/320995/nature14128.pdf?sequence=2
Cloin, B., Hoogenraad, C., Mikhaylova, M., & Kapitein, L. (2015). Single molecule localization microscopy to study neuronal microtubule organization. In Immunocytochemistry and Related Techniques (pp. 389-408). (Neuromethods; Vol. 101). Humana Press. https://doi.org/10.1007/978-1-4939-2313-7_21
https://dspace.library.uu.nl/bitstream/handle/1874/428547/978_1_4939_2313_7_21.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/428547/978_1_4939_2313_7_21.pdf?sequence=1
2014
Scholarly publications
Yau, K. W., van Beuningen, S. F. B., Cunha-Ferreira, I., Cloin, B. M. C., van Battum, E. Y., Will, L., Schätzle, P., Tas, R. P., van Krugten, J., Katrukha, E. A., Jiang, K., Wulf, P. S., Mikhaylova, M., Harterink, M., Pasterkamp, R. J., Akhmanova, A., Kapitein, L. C., & Hoogenraad, C. C. (2014). Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development. Neuron, 82(5), 1058-73. https://doi.org/10.1016/j.neuron.2014.04.019
Adrian, M., Kusters, R., Wierenga, C. J., Storm, C., Hoogenraad, C. C., & Kapitein, L. C. (2014). Barriers in the brain: resolving dendritic spine morphology and compartmentalization. Frontiers in Neuroanatomy, 8, 142. https://doi.org/10.3389/fnana.2014.00142
Gumy, L., Katrukha, E., Kapitein, L., & Hoogenraad, C. (2014). New insights into mRNA trafficking in axons. Developmental Neurobiology, 74(3), 233-244. https://doi.org/10.1002/dneu.22121
Doodhi, H., Katrukha, E., Kapitein, L., & Akhmanova, A. (2014). Mechanical and geometrical constraints control kinesin-based microtubule guidance. Current Biology, 24(3), 322-328. https://doi.org/10.1016/j.cub.2014.01.005
Other output
Kevenaar, J., Bianchi, S., van Spronsen, M., Olieric, N., Lipka, J., Mikhaylova, M., Rietman, L., Wulf, P., Beier, A., Harschnitz, O., Geijsen, N., Kapitein, L., de Graaff, E., Pasterkamp, R. J., Akhmanova, A., Steinmetz, M. O., & Hoogenraad, C. (2014). Goldberg-Shprintzen syndrome protein KBP controls kinesin activity to regulate vesicle trafficking and neuronal development. Poster session presented at Gordon Conference: "Cell Biology of the Neuron" 2014, Waterville Valley, United States.
Franker, M., Kapitein, L., & Hoogenraad, C. (2014). Unraveling the regulatory mechanisms that govrn KIF17 transport in vivo. Poster session presented at Dutch Biophysics meeting 2014, Netherlands.
Kevenaar, J., Bianchi, S., van Spronsen, M., Olieric, N., Lipka, J., Mikhaylova, M., Rietman, L., Wulf, P., Beier, A., Harschnitz, O., Geijsen, N., Kapitein, L., de Graaff, E., Pasterkamp, R. J., Akhmanova, A., Steinmetz, M. O., & Hoogenraad, C. (2014). Goldberg-Shprintzen syndrome protein KBP controls kinesin activity to regulate vesicle trafficking and neuronal development.
Doodhi, H., Katrukha, E., Kapitein, L., & Akhmanova, A. (2014). Mechanistic insights into kinesin-based microtubule guidance. Poster session presented at EMBO Conference: Microtubules: Structure, Regulation and Functions, Heidelberg, Germany.
2013
Scholarly publications
Kapitein, L. C., van Bergeijk, P., Lipka, J., Keijzer, N., Wulf, P. S., Katrukha, E. A., Akhmanova, A., & Hoogenraad, C. C. (2013). Myosin-V opposes microtubule-based cargo transport and drives directional motility on cortical actin. Current Biology, 23(9), 828-34. https://doi.org/10.1016/j.cub.2013.03.068
van Spronsen, M., Mikhaylova, M., Lipka, J., Schlager, M. A., van den Heuvel, D. J., Kuijpers, M., Wulf, P. S., Keijzer, N., Demmers, J., Kapitein, L. C., Jaarsma, D., Gerritsen, H., Akhmanova, A., & Hoogenraad, C. C. (2013). TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites. Neuron, 77(3), 485-502. https://doi.org/10.1016/j.neuron.2012.11.027
Kapitein, L. C., van Bergeijk, P. M., Lipka, J. E., Keijzer, N., Wulf, P. S., Katrukha, Y., Akhmanova, A. S., & Hoogenraad, C. C. (2013). Myosin-V opposes microtuble-based cargo transport and drives directional motility on cortical actin. Current Biology, 23(9), 828-834.
Mohan, R., Katrukha, Y., Doodhi, H., Smal, I., Meijering, E., Kapitein, L. C., Steinmetz, M. O., & Akhmanova, A. S. (2013). End-binding proteins sensitize microtubules to the action of microtubule-targeting agents. Proceedings of the National Academy of Sciences of the United States of America, 110(22), 8900-8905.
Gumy, L. F., Chew, D. J., Tortosa, E., Katrukha, Y., Kapitein, L. C., Tolkovsky, A. M., Hoogenraad, C. C., & Fawcett, J. W. (2013). The kinesin-2 family member KIF3C regulates microtubule dynamics and is required for axon growth and regeneration. Journal of Neuroscience, 33(28), 11329-11345.
Other output
Estevez da Silva, M., Kapitein, L. C., Adrian, M., Wierenga, C. J., & Hoogenraad, C. C. (2013). Controlled delivery of AMPA receptors-containing recycling endosomes to excitatory synapsis.. Poster session presented at Gordon Research Conference-Excitatory Synapsis & Brain Function, Les Diablerets, Switzerland.
van Bergeijk, P., Adrian, M., Hoogenraad, C. C., & Kapitein, L. C. (2013). Optical control of Intracellular Transport. Poster session presented at american Society of Cell Biology (ASCB) Annual meeting.
Estevez da Silva, M., Kapitein, L. C., Adrian, M., Wierenga, C. J., & Hoogenraad, C. C. (2013). Controlled delivery of AMPA receptors-containing recycling endosomes to excitatory synapsis. Poster session presented at 20th Annual ONWAR PhD meeting, Woudschoten, the Netherlands.
Estevez da Silva, M., Kapitein, L. C., Adrian, M., Wierenga, C. J., & Hoogenraad, C. C. (2013). Controlled delivery of AMPA receptors-containing recycling endosomes to excitatory synapses. Poster session presented at Gordon Research Seminar-Excitatory Synapsis & Brain Funtion, Les Diablerets, Switzerland.
Cloin, B. M. C., Katrukha, Y., Mikhaylova, M., Hoogenraad, C. C., & Kapitein, L. C. (2013). Super-resolution of the cytoskeleton to understand polarized transport in neurons. Poster session presented at STW Nano dag, Utrecht, The Netherlands.
Yau, K. W., van Beuningen, S. F. B., Cloin, B. M. C., Jiang, K., Katrukha, Y., Harterink, M., Wulf, P. S., Akhmanova, A. S., Kapitein, L. C., & Hoogenraad, C. C. (2013). Microtubule minus-end binding protein CAMSAP2 controls specification and dendrite development. Poster session presented at The 5th EMBO meeting, Amsterdam, The Netherlands.
Franker, M. A. M. L., Kapitein, L. C., & Hoogenraad, C. C. (2013). Kinesin-1 and kinesin-2 motor proteins are regulated by different mechanisms in living cells.. Poster session presented at Molecular and Cellular Biophysics, Veldhoven, The Netherlands.
Kevenaar, J. T., Bianchi, S., van Spronsen, M., Olieric, N., Lipka, J. E., Mikhaylova, M., Rietman, L. M., Kapitein, L. C., de Graaff, E., Keijzer, N., Wulf, P. S., Pasterkamp, J. R., Steinmetz, M. O., Hoogenraad, C. C., & Akhmanova, A. S. (2013). Misregulation of KIF1A-mediated synaptic vesicle transport underlies Goldberg-Shprintzen syndrome. Poster session presented at Annual PhD ONWAR meeting, Zeist, The Netherlands.
Mikhaylova, M., Katrukha, Y., Brakel, H. X., van Bergen en Henegouwen, P. M. P., Akhmanova, A. S., Hoogenraad, C. C., & Kapitein, L. C. (2013). Inducible targeting of cytoplasmic quantum dots.. Poster session presented at Dutch meeting on Molecular and Cellular Biophysics, Veldhoven, The Netherlands.
Gumy, L. F., Chew, D. J., Tortosa Binacua, E., Katrukha, Y., Kapitein, L. C., Tolkovsky, A. M., Hoogenraad, C. C., & Fawcett, J. W. (2013). The kinesin-2 family member KIF3C regulates microtubule dynamics and is required for axon growth and regeneration.. Poster session presented at Symposia: Cell biology and pathology of axons, Lake Tahoe, Ca, USA.
van Bergeijk, P. M., Adrian, M., Hoogenraad, C. C., & Kapitein, L. C. (2013). Optogenetic control of Intracellular Transport. Poster session presented at American Society of Cell Biology (ASCB), New Orleans, USA.
Yau, K. W., van Beuningen, S. F. B., Cloin, B. M. C., Jiang, K., Katrukha, Y., Harterink, M., Wulf, P. S., Akhmanova, A. S., Kapitein, L. C., & Hoogenraad, C. C. (2013). Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development. Poster session presented at Annual Dutch meeting on Molecular and Cellular Biophysics 2013, Veldhoven, The Netherlands.
2012
Other output
Mikhaylova, M., Reddy, P. P., Hradsky, J., Kapitein, L. C., Hoogenraad, C. C., & Kreutz, M. R. (2012). Calcium dependent regulation of actin dynamcis in spines via caldendrin and cortactin. Abstract from 8th FENS Forum of Neuroscience, Barcelona, Spain.
van den Berg, R., Katrukha, Y., Cloin, B. M. C., Mikhaylova, M., Hoogenraad, C. C., & Kapitein, L. C. (2012). From Tip to Tail; Superresolution imaging of cytoskeleton proteins. Poster session presented at The Dutch meeting on Molecular and Cellular Biophysics, Veldhoven.
Lipka, J. E., van Spronsen, C. S. A. M., Franker, A. M., Estevez da Silva, M., Kapitein, L. C., & Hoogenraad, C. C. (2012). Kinesin-1 and dynein motors drive polarized mitochondria transport in neurons. Poster session presented at The Dutch meeting on Molecular and Cellular Biophysics, Veldhoven.
Gumy, L. F., Chew, D., Katrukha, Y., Kapitein, L. C., Tolkovsky, A. M., Hoogenraad, C. C., & Fawcett, J. W. (2012). The motor protein Kif3c regulates microtubule dynamics and is required for axon growth and regeneration. Abstract from Gordon Research Conference "Cell Biology of the Neuron", Waterville, NH, USA.
van den Berg, R., Katrukha, Y., Cloin, B. M. C., Mikhaylova, M., Hoogenraad, C. C., & Kapitein, L. C. (2012). From Tip to Tail; Superresolution imaging of cytoskeleton proteins. Abstract from The Dutch meeting on Molecular and Cellular Biophysics, Veldhoven.
Lipka, J. E., van Spronsen, C. S. A. M., Franker, A. M., Estevez da Silva, M., Kapitein, L. C., & Hoogenraad, C. C. (2012). Kinesin-1 and dynein motors drive polarized mitochondria transport in neurons. Abstract from The Dutch meeting on Molecular and Cellular Biophysics, Veldhoven.
Mikhaylova, M., Reddy, P. P., Hradsky, J., Kapitein, L. C., Hoogenraad, C. C., & Kreutz, M. R. (2012). Calcium dependent regulation of actin dynamcis in spines via caldendrin and cortactin. Poster session presented at 8th FENS Forum of Neuroscience, Barcelona, Spain.
Lipka, J. E., van Spronsen, C. S. A. M., Franker, M. A. M. L., Estevez da Silva, M., Kapitein, L. C., & Hoogenraad, C. C. (2012). Kinesin-1 and dynein motors drive polarized mitochondria transport in neurons. Poster session presented at 8th FENS Forum of Neuroscience, Barcelona, Spain.
2011
Scholarly publications
Kapitein, L. C., Yau, K. W., Gouveia, S. M., van der Zwan, W. A., Wulf, P. S., Keijzer, N., Demmers, J., Jaworski, J., Akhmanova, A. S., & Hoogenraad, C. C. (2011). NMDA receptor activation suppresses microtubule growth and spine entry. Journal of Neuroscience, 31(22), 8194-8209.
Kapitein, L. C., & Hoogenraad, C. C. (2011). Which way to go? Cytoskeletal organization and polarized transport in neurons. Molecular and Cellular Neuroscience, 46(1), 9-20. https://doi.org/10.1016/j.mcn.2010.08.015
Hellal, F., Hurtado, A., Ruschel, J., Flynn, K. C., Laskowski, C. J., Umlauf, M., Kapitein, L. C., Strikis, D., Lemmon, V., Bixby, J., Hoogenraad, C. C., & Bradke, F. (2011). Microtubule stabilization reduces scarring and causes axon regeneration after spinal cord injury. Science, 331(6019), 928-931. https://doi.org/10.1126/science.1201148
2010
Scholarly publications
Stiess, M., Maghelli, N., Kapitein, L. C., Gomis-Rüth, S., Wilsch-Bräuninger, M., Hoogenraad, C. C., Tolić-Nørrelykke, I. M., & Bradke, F. (2010). Axon extension occurs independently of centrosomal microtubule nucleation. Science, 327(5966), 704-7. https://doi.org/10.1126/science.1182179
Kapitein, L. C., Schlager, M. A., Kuijpers, M., Wulf, P. S., van Spronsen, M., MacKintosh, F. C., & Hoogenraad, C. C. (2010). Mixed microtubules steer dynein-driven cargo transport into dendrites. Current Biology, 20(4), 290-9. https://doi.org/10.1016/j.cub.2009.12.052
Kapitein, L. C., Schlager, M. A., van der Zwan, W. A., Wulf, P. S., Keijzer, N., & Hoogenraad, C. C. (2010). Probing intracellular motor protein activity using an inducible cargo trafficking assay. Biophysical Journal, 99(7), 2143-52. https://doi.org/10.1016/j.bpj.2010.07.055
Hoogenraad, C. C., Popa, I. L., Futai, K., Martinez Sanchez, E., Wulf, P. S., van Vlijmen, T., Dortland, B., Oorschot, V. M. J., Govers, R., Monti, M., Heck, A. J. R., Sheng, M., Klumperman, J., Rehmann, H., Jaarsma, D., Kapitein, L. C., & van der Sluijs, P. (2010). Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes. PloS Biology [E], 8(1), e1000283. http://www.ncbi.nlm.nih.gov/pubmed/20098723
2009
Scholarly publications
Jaworski, J., Kapitein, L. C., Gouveia, S. M., Dortland, B. R., Wulf, P. S., Grigoriev, I., Camera, P., Spangler, S. A., Di Stefano, P., Demmers, J., Krugers, H., Defilippi, P., Akhmanova, A., & Hoogenraad, C. C. (2009). Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity. Neuron, 61(1), 85-100. https://doi.org/10.1016/j.neuron.2008.11.013