Publications
2023
Scholarly publications
Pérez-Ortega, J., van Harten, R. M., Haagsman, H. P., & Tommassen, J. (2023). Physiological consequences of inactivation of lgmB and lpxL1, two genes involved in lipid A synthesis in Bordetella bronchiseptica. Research in Microbiology, 174(5), [104049]. https://doi.org/10.1016/j.resmic.2023.104049
2022
Scholarly publications
Uruén, C., García, C., Fraile, L., Tommassen, J., & Arenas, J. (2022). How Streptococcus suis escapes antibiotic treatments. Veterinary Research, 53(1), [91]. https://doi.org/10.1186/s13567-022-01111-3
Pérez-Ortega, J., Van boxtel, R., De jonge, E. F., & Tommassen, J. (2022). Regulated Expression of lpxC Allows for Reduction of Endotoxicity in Bordetella pertussis. International Journal of Molecular Sciences, 23(14), 1-14. [8027]. https://doi.org/10.3390/ijms23148027
Foudraine, D. E., Aarents, C. N. M., Wattel, A. A., Van boxtel, R., Strepis, N., Ten kate, M. T., Verbon, A., Luider, T. M., Klaassen, C. H. W., Hays, J., Dekker, L. J. M., Tommassen, J., & Goessens, W. H. F. (2022). Liquid Chromatography-Tandem Mass Spectrometry Analysis Demonstrates a Decrease in Porins and Increase in CMY-2 β-Lactamases in Escherichia coli Exposed to Increasing Concentrations of Meropenem. Frontiers in Microbiology, 13, [793738]. https://doi.org/10.3389/fmicb.2022.793738
De jonge, E. F., Vogrinec, L., Van boxtel, R., & Tommassen, J. (2022). Inactivation of the Mla system and outer-membrane phospholipase A results in disrupted outer-membrane lipid asymmetry and hypervesiculation in Bordetella pertussis. Current Research in Microbial Sciences, 3, [100172]. https://doi.org/10.1016/j.crmicr.2022.100172
De jonge, E. F., & Tommassen, J. (2022). Conditional growth defect of Bordetella pertussis and Bordetella bronchiseptica ferric uptake regulator (fur) mutants. FEMS Microbiology Letters, 369(1), 1-7. [fnac047]. https://doi.org/10.1093/femsle/fnac047
de Jonge, E. F., van Boxtel, R., Balhuizen, M. D., Haagsman, H. P., & Tommassen, J. (2022). Pal depletion results in hypervesiculation and affects cell morphology and outer-membrane lipid asymmetry in bordetellae. Research in Microbiology, 173(4-5), 1-13. [103937]. https://doi.org/10.1016/j.resmic.2022.103937
2021
Scholarly publications
Arenas, J., Szabo, Z., van der Wal, J., Maas, C., Riaz, T., Tønjum, T., & Tommassen, J. (2021). Serum proteases prevent bacterial biofilm formation: role of kallikrein and plasmin. Virulence, 12(1), 2902-2917. https://doi.org/10.1080/21505594.2021.2003115
De Geyter, D., Vanstokstraeten, R., Crombé, F., Tommassen, J., Wybo, I., & Piérard, D. (2021). Sink drains as reservoirs of VIM-2 metallo-β-lactamase-producing Pseudomonas aeruginosa in a Belgian intensive care unit: relation to patients investigated by whole-genome sequencing. Journal of Hospital Infection, 115, 75-82. https://doi.org/10.1016/j.jhin.2021.05.010
Pérez-Ortega, J., Van Harten, R. M., Van Boxtel, R., Plisnier, M., Louckx, M., Ingels, D., Haagsman, H. P., & Tommassen, J. (2021). Reduction of endotoxicity in Bordetella bronchiseptica by lipid A engineering: Characterization of lpxL1 and pagP mutants. Virulence, 12(1), 1452-1468. https://doi.org/10.1080/21505594.2021.1929037
Balhuizen, M. D., Versluis, C. M., Van Harten, R. M., De Jonge, E. F., Brouwers, J. F., Van De Lest, C. H. A., Veldhuizen, E. J. A., Tommassen, J., & Haagsman, H. P. (2021). PMAP-36 reduces the innate immune response induced by Bordetella bronchiseptica-derived outer membrane vesicles. Current Research in Microbial Sciences, 2, [100010]. https://doi.org/10.1016/j.crmicr.2020.100010
De Jonge, E. F., Balhuizen, M. D., Van Boxtel, R., Wu, J., Haagsman, H. P., & Tommassen, J. (2021). Heat shock enhances outer-membrane vesicle release in Bordetella spp. Current Research in Microbial Sciences, 2, 1-11. [100009]. https://doi.org/10.1016/j.crmicr.2020.100009
Uruén, C., Chopo-Escuin, G., Tommassen, J., Mainar-Jaime, R. C., & Arenas, J. (2021). Biofilms as promoters of bacterial antibiotic resistance and tolerance. Antibiotics, 10(1), 1-36. [3]. https://doi.org/10.3390/antibiotics10010003
2020
Scholarly publications
Arenas Busto, J. A., Paganelli, F. L., Rodríguez-Castaño, P., Cano-Crespo, S., van der Ende, A., van Putten, J. P. M., & Tommassen, J. P. M. (2020). Expression of the Gene for Autotransporter AutB of Neisseria meningitidis Affects Biofilm Formation and Epithelial Transmigration. In S. Bleves, R. Voulhoux, B. Ize, T. Sana, & D. Monack (Eds.), Protein Export and Secretion Among Bacterial Pathogens (pp. 08-24). Frontiers Media SA.
Arenas, J., Pupo, E., Phielix, C., David, D., Zariri, A., Zamyatina, A., Tommassen, J., & Van Der Ley, P. (2020). Shortening the Lipid A Acyl Chains of Bordetella pertussis Enables Depletion of Lipopolysaccharide Endotoxic Activity. Vaccines, 8(4), [594]. https://doi.org/10.3390/vaccines8040594
Arenas, J., Catón, L., Van Den Hoeven, T., De Maat, V., Cruz Herrero, J., & Tommassen, J. (2020). The outer-membrane protein MafA of Neisseria meningitidis constitutes a novel protein secretion pathway specific for the fratricide protein MafB. Virulence, 11(1), 1701-1715. https://doi.org/10.1080/21505594.2020.1851940
2019
Scholarly publications
Arenas, J., Pupo, E., De Jonge, E., Pérez-Ortega, J., Schaarschmidt, J., Van Der Ley, P., & Tommassen, J. (2019). Substrate specificity of the pyrophosphohydrolase LpxH determines the asymmetry of Bordetella pertussis lipid A. Journal of Biological Chemistry, 294(20), 7982-7989. https://doi.org/10.1074/jbc.RA118.004680
Arenas, J., Bossers-de Vries, R., Harders-Westerveen, J., Buys, H., Ruuls-van Stalle, L. M. F., Stockhofe-Zurwieden, N., Zaccaria, E., Tommassen, J., Wells, J. M., Smith, H. E., & de Greeff, A. (2019). In vivo transcriptomes of Streptococcus suis reveal genes required for niche-specific adaptation and pathogenesis. Virulence, 10(1), 334-351. https://doi.org/10.1080/21505594.2019.1599669
2017
Scholarly publications
Tommassen, J., & Arenas Busto, J. (2017). Biological Functions of the Secretome of Neisseria meningitidis. Frontiers in cellular and infection microbiology, 7, [256]. https://doi.org/10.3389/fcimb.2017.00256
Pérez-Ortega, J., Rodríguez, A., Ribes, E., Tommassen, J., & Arenas Busto, J. (2017). Interstrain cooperation in meningococcal biofilms: Role of autotransporters NalP and AutA. Frontiers in Microbiology, 8, [434]. https://doi.org/10.3389/fmicb.2017.00434
Arenas Busto, J., & Tommassen, J. (2017). Meningococcal Biofilm Formation: Let's Stick Together. Trends in Microbiology, 25(2), 113-124. https://doi.org/10.1016/j.tim.2016.09.005
Tommassen - van Boxtel, R., Wattel, A. A., Arenas Busto, J., Goessens, W. H. F., & Tommassen, J. (2017). Acquisition of carbapenem resistance by plasmid-encoded-AmpC-expressing Escherichia coli. Antimicrobial Agents and Chemotherapy, 61(1), [e01413-16]. https://doi.org/10.1128/AAC.01413-16
2015
Scholarly publications
Tommassen, J. P. M., & Wosten, H. A. B. (2015). Microbial cell surfaces and secretion systems. In B. Lugtenberg (Ed.), Principles of plant-microbe interactions: Microbes for sustainable agriculture (pp. 33-44). Springer. https://doi.org/10.1007/978-3-319-08575-3_6
https://dspace.library.uu.nl/bitstream/handle/1874/328045/Microbial.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/328045/Microbial.pdf?sequence=1
Arenas Busto, J. A., Cano, S., Nijland, R., van Dongen, V., Rutten, L., van der Ende, A., & Tommassen, J. P. M. (2015). The meningococcal autotransporter AutA is implicated in autoaggregation and biofilm formation. Environmental Microbiology, 17(4), 1321-37. https://doi.org/10.1111/1462-2920.12581
Paltansing, S., Kraakman, M., van Boxtel, H. A. M., Kors, I., Wessels, E., Goessens, W., Tommassen, J. P. M., & Bernards, A. (2015). Increased expression levels of chromosomal AmpC β-lactamase in clinical Escherichia coli isolates and their effect on susceptibility to extended-spectrum cephalosporins. Microbial Drug Resistance, 21(1), 7-16. https://doi.org/10.1089/mdr.2014.0108
Putker, F., Bos, M. P., & Tommassen, J. P. M. (2015). Transport of lipopolysaccharide to the Gram-negative bacterial cell surface. FEMS Microbiology Reviews, 39(6), 985-1002. https://doi.org/10.1093/femsre/fuv026
van 't Wout, E. F. A., van Schadewijk, A., van Boxtel, R., Dalton, L. E., Clarke, H. J., Tommassen, J. P. M., Marciniak, S. J., & Hiemstra, P. S. (2015). Virulence Factors of Pseudomonas aeruginosa Induce Both the Unfolded Protein and Integrated Stress Responses in Airway Epithelial Cells. PLoS Pathogens, 11(6), [e1004946]. https://doi.org/10.1371/journal.ppat.1004946
Arenas Busto, J. A., de Maat, V., Caton Alcubierre, L., Krekorian, M., Herrero, J. C., Ferrara, F., & Tommassen, J. P. M. (2015). Fratricide activity of MafB protein of N. meningitidis strain B16B6. BMC Microbiology [E], 15(156). https://doi.org/10.1186/s12866-015-0493-6
Bos, M. P., Boxtel, R. T., & Tommassen, J. P. M. (2015). Experimental Methods for Studying the BAM Complex in Neisseria meningitidis. Methods in Molecular Biology, 1329, 33-49. https://doi.org/10.1007/978-1-4939-2871-2_3
Berendsen, R. L., van Verk, M. C., Stringlis, I. A., Zamioudis, C., Tommassen, J., Pieterse, C. M. J., & Bakker, P. A. H. M. (2015). Unearthing the genomes of plant-beneficial Pseudomonas model strains WCS358, WCS374 and WCS417. BMC Genomics, 16, [539]. https://doi.org/10.1186/s12864-015-1632-z
2014
Scholarly publications
van Dam, V., Roussel-Jazédé, V., Arenas Busto, J., Bos, M., & Tommassen, J. (2014). Outer membrane-embedded and -associated proteins and their role in adhesion and pathogenesis. In H. Remaut, & R. Frozes (Eds.), Bacterial Membranes: Structural and Molecular Biology (pp. 415-447). Caister Academic press, Norfolk (UK).
Adams, H., Horrevoets, W. M., Adema, S. M., Carr, H. E. V., van Woerden, R. E., Koster, M., & Tommassen, J. (2014). Inhibition of biofilm formation by Camelid single-domain antibodies against the flagellum of Pseudomonas aeruginosa. Journal of Biotechnology, 186, 66-73. https://doi.org/10.1016/j.jbiotec.2014.06.029
Adams, H., Horrevoets, W. M., Adema, S. M., Carr, H. E. V., van Woerden, R. E., Koster, M., & Tommassen, J. (2014). Reprint of "Inhibition of biofilm formation by Camelid single-domain antibodies against the flagellum of Pseudomonas aeruginosa". Journal of Biotechnology, 191, 131-138. https://doi.org/10.1016/j.jbiotec.2014.09.022
van Dam, V., Roussel-Jazédé, V., Arenas Busto, J., Langereis, J. D., Tommassen, J., & van Ulsen, P. (2014). Variable processing of the IgA protease autotransporter at the cell surface of Neisseria meningitidis. Microbiology, 160(11), 2421-2431. https://doi.org/10.1099/mic.0.082511-0
Bos, M. P., Grijpstra, J., Tommassen - van Boxtel, H., & Tommassen, J. (2014). Involvement of Neisseria meningitidis Lipoprotein GNA2091 in the Assembly of a Subset of Outer Membrane Proteins. Journal of Biological Chemistry, 289(22), 15602-15610. https://doi.org/10.1074/jbc.M113.539510
Putker, F., Grutsch, A., Tommassen, J., & Bos, M. P. (2014). Ght Protein of Neisseria meningitidis Is Involved in the Regulation of Lipopolysaccharide Biosynthesis. Journal of Bacteriology, 196(4), 780-789. https://doi.org/10.1128/JB.00943-13
Sinnige, T., Weingarth, M., Renault, M., Baker, L., Tommassen, J., & Baldus, M. (2014). Solid-State NMR studies of full-length BamA in lipid bilayers suggest limited overall POTRA mobility. Journal of Molecular Biology, 426(9), 2009-2021. https://doi.org/10.1016/j.jmb.2014.02.007
2013
Scholarly publications
Goessens, W. H., van der Bij, A. K., van Boxtel, R., Pitout, J. D., van Ulsen, J. P., Melles, D. C., & Tommassen, J. P. M. (2013). Antibiotic trapping by plasmid-encoded CMY-2 ß-lactamase combined with reduced outer membrane permeability as a mechanism of carapenem resistance in Escherichia coli. Antimicrobial Agents and Chemotherapy, 57, 3941-3949.
Grijpstra, J., Bos, M. P., & Tommassen, J. P. M. (2013). Assembly of bacterial outer membrane proteins. In A. H. Delcour (Ed.), Bacterial Cell Surfaces: Methods and Protocols (pp. 223-227). Humana Press.
Grijpstra, J., Arenas Busto, J. A., Rutten, L., & Tommassen, J. P. M. (2013). Autotransporter secretion: varying on a theme. Research in Microbiology, 164, 562-582.
Putker, F. M., Tommassen-van Boxtel, H. A. M., Stork, M., Rodriguez-Herva, J. J., Koster, M. C., & Tommassen, J. P. M. (2013). The type II secretion system (Xcp) of Pseudomonas putida is active and involved in the secretion of phosphatases. Environmental Microbiology, 15, 2658-2671.
Arenas Busto, J. A., Schipper, K., van Ulsen, J. P., van der Ende, A., & Tommassen, J. P. M. (2013). Domain exchange at the 3'end of the gene encoding the fratricide meningococcal two-partner secretion protein A. BMC Genomics, 14, 622.
van der Meeren, R., Wen, Y., van Gelder, P., Tommassen, J. P. M., Devreese, B., & Savvides, S. N. (2013). New insights into the assembly of bacterial secretins. Structural studies of the periplasmic domain of XcpQ from Pseudomonas aeruginosa. Journal of Biological Chemistry, 288, 1214-1225.
Volokhina, E. B., Grijpstra, J., Beckers, F. H. R., Lindh, E., Robert, V. M. V., Tommassen, J. P. M., & Bos, M. P. (2013). Species-specificity of the BamA component of the bacterial outer membrane protein-assembly machinery. PLoS One, 8, e85799.
Hubert, K., Devos, N., Mordhorst, I., Tans, C., Baudoux, G., Feron, C., Goraj, K. K., Tommassen, J. P. M., vogel, U., Poolman, J. T., & Weynants, V. (2013). ZnuD, a potential candidate for a simple and universal Neisseria meningitidis vaccine. Infection and Immunity, 81, 1915-1927.
2012
Scholarly publications
Kuhn, K., Baumann, C., Tommassen, J. P. M., & Prinz, T. C. (2012). TMT labeling for the quantive analysis of adaptive responses in meningcoccal proteome. In M. Christodoulides (Ed.), Neisseria meningitidis: advanced methods and protocols. (pp. 127-141). (Meth. Mol. Biol.; No. 799). Humana Press.
2011
Scholarly publications
Renault, M. A. M., Bos, M. P., Tommassen, J. P. M., & Baldus, M. (2011). Solid-state NMR on a large multidomain integral membrane protein: the outer membrane protein assembly factor BamA. Journal of the American Chemical Society, 133(12), 4175-4177. https://doi.org/10.1021/ja109469c
Bos, M. P., & Tommassen, J. P. M. (2011). The LptD chaperone LptE is not directly involved in lipopolysaccharide transport in Neisseria meningitidis. Journal of Biological Chemistry, 286, 28688-28696.
2010
Scholarly publications
Arenas, J., Dijken, H., Hamstra, H. J., Tommassen, J. P. M., & van der Ley, P. (2010). Coincorporation of LpxL1 and PagL mutant lipopolysaccharides into liposomes with Nessieria meningitidis opacity protein: Influence on endotoxic and adjuvant activity. Clinical and Vaccine Immunology, 17, 487-495.
Remans, K., Pauwels, K., van Ulsen, J. P., Buts, L., Cornelis, P., Tommassen, J. P. M., Savvides, S. N., Decanniere, K., & van Gelder, P. (2010). Hydrophobid surface patches on LolA of Pseudomonas aeruginosa are essential for lipoprotein binding. Journal of Molecular Biology, 401, 921-930.
Other output
Arenas Busto, J. A., & Tommassen, J. P. M. (2010). The autotransporter NalP, a phase-variable expressed protease, regulates the initiation of meningococcal biofilm formation through eDNA. Poster session presented at Joint meeting CW study groups Protein Research, Nucleic Acids, and Lipids & Biomembranes, Veldhoven.
Putker, F. M., Tommassen-van Boxtel, H. A. M., Stork, M., Tommassen, J. P. M., & Koster, M. C. (2010). Role of type II secretion and the Tat pathway of Pseudomonas putida in phosphate acquisition. Poster session presented at ALW Platform Molecular Genetics, Lunteren.
2009
Scholarly publications
Volokhina, E. B., Beckers, F. H. R., Tommassen, J. P. M., & Bos, M. P. (2009). The ß-barrel outer membrane protein assembly complex of Neisseria meningitidis. Journal of Bacteriology, 191, 7074-7085.
van Ulsen, J. P., Kuhn, K., Prinz, T. C., Legner, H., Schmid, P., Baumann, C., & Tommassen, J. P. M. (2009). Identification of proteins of Neisseria meningitidis induced under iron-limiting conditions using the isobaric tandem mass tag (TMT) labeling approach. Proteomics, 9, 1771-1781.
Walther, D. M., Rapaport, D., & Tommassen, J. P. M. (2009). Biogenesis of ß-barrel membrane proteins in bacteria and eukaryotes: evolutionary conservation and divergence. Cellular and Molecular Life Sciences, 66, 2789-2804.
2008
Scholarly publications
Senf, F., Tommassen, J. P. M., & Koster, M. C. (2008). Polar secretion of proteins via the type II secretion system in Pseudomonas aeruginosa. Microbiology, 154, 3025-3032.
Geurtsen, J. J. G., Fransen, F., Vandebriel, R. J., Gremmer, E. R., de la Fonteyne-Blankestijn, L. J. J., Kuipers, B., Tommassen, J. P. M., & van der Ley, P. (2008). Supplementation of whole-cell pertussis vaccines with lipopolysaccharide analogs: modification of vaccine-induced immune responses. Vaccine, 26, 899-906.
2007
Scholarly publications
Arts, J. G., de Groot, A., Ball, G., Durand, E., El Khattabi, M., Filloux, A., Tommassen, J. P. M., & Koster, M. C. (2007). Interaction domains in the Pseudomonas aeruginosa type II secretory apparatus component XcpS. Microbiology, 153, 1582-1592.
Tommassen, J. P. M. (2007). Getting into and through the outer membrane. Science, 317, 903-904.
Weynants, V. E., Feron, C. M., Goraj, K. K., Bos, M. P., Denoel, P. A., Verlant, V. G., Tommassen, J. P. M., Peak, I. R. A., Judd, R. C., Jennings, M. P., & Poolman, J. T. (2007). Additive and synergic bactericidal activity of antibodies directed against minor outer membrane proteins of Neisseria meningitidis. Infection and Immunity, 75, 5434-5442.
Pauwels, K., van Molle, I., Tommassen, J. P. M., & van Gelder, P. (2007). Chaperoning Anfinsen: the steric foldases. Molecular Microbiology, 64, 917-922.
Geurtsen, J. J. G., Vandebriel, R. J., Gremmer, E. R., Kuipers, B., Tommassen, J. P. M., & van der Ley, P. A. (2007). Consequences of the expression of lipopolysaccharide-modifying enzymes for the efficacy and reactogenicity of whole-cell pertussis vaccines. Microbes and Infection, 9, 1096-1103.
Kortekaas, J. A., Petterson, A., van der Biezen, J., Weynants, V. E., van der Ley, P., Poolman, J., Bos, M. P., & Tommassen, J. P. M. (2007). Shielding of immunogenic domains in Neisseria meningitidis FrpB (FetA) by the major variable region. Vaccine, 25, 72-84.
Geurtsen, J. J. G., Banus, H. A., Gremmer, E. R., Ferguson, H., de la Fonteyne-Blankestijn, L. J. J., Vermeulen, J. P., Dormans, J. A. M. A., Tommassen, J. P. M., van der Ley, P. A., Mooi, F. R., & Vandebriel, R. J. (2007). LPS analogs improve the efficacy of accellular pertussis vaccine and reduce type I hypersensitivity in mice. Clinical and Vaccine Immunology, 14, 821-829.
2006
Scholarly publications
van Ulsen, J. P., Gros, P., & Tommassen, J. P. M. (2006). Structure and function of the translocator domain of bacterial autotransporters. In R. Grisshammer, & S. Buchanan (Eds.), Structural biology of membrane proteins (pp. 270-287). RSC.
El Khattabi, M., Adams, H., Heezius, E., hermans, P., Detmers, F., Maassen, B. T. H., van der Ley, P., Tommassen, J. P. M., Verrips, C. T., & Stam, J. C. (2006). Llama single-chain antibody that blocks lipopolysaccharide binding and signalling: prospects for therapeutic applications. Clinical and Vaccine Immunology, 13, 1079-1086.
Kortekaas, J. A., Müller, S. A., Ringler, P., Gregorini, M., Weynants, V. E., Rutten, L., Bos, M. P., & Tommassen, J. P. M. (2006). Immunogenicity and structural characterisation of an in vitro folded meningococcal siderophore receptor (FrpB, FetA). Microbes and Infection, 8, 2145-2153.
https://dspace.library.uu.nl/bitstream/handle/1874/19475/10.1016-j.micinf.2006.04.011.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/19475/10.1016-j.micinf.2006.04.011.pdf?sequence=1
Pettersson, A., Kortekaas, J. A., Weynants, V. E., Voet, P., Poolman, J. T., Bos, M. P., & Tommassen, J. P. M. (2006). Vaccine potential of the Neisseria meningitidis lactoferrin-binding proteins LbpA and LbpB. Vaccine, 24, 3545-3557.
Geurtsen, J. J. G., Steeghs, L. J. J. M., Hamstra, H. J., ten Hove, J., de Haan, A., Kuipers, B., Tommassen, J. P. M., & van der Ley, P. (2006). Expression of LPS-modifying enzymes PagP and PagL modulates the endotoxic activity of Bordetella pertussis. Infection and Immunity, 74, 5574-5585.
2005
Scholarly publications
Tefsen, B., Bos, M. P., Beckers, F. H. R., Tommassen, J. P. M., & de Cock, J. J. P. A. (2005). MsbA is not required for phospholipid transport in Neisseria meningitidis. Journal of Biological Chemistry, 280, 35961-35966.
Hays, J. P., van Selm, S., Hoogenboezem, T., Estevao, S., Eadie, K., van Veelen, P., Tommassen, J. P. M., van Belkum, A., & Hermans, P. W. M. (2005). Identification and characterization of a novel outer membrane protein (OMP J) of Moraxella catarrhalis that exists in two major forms. Journal of Bacteriology, 187, 7977-7984.
Tefsen, B., Geurtsen, J. J. G., Beckers, F. H. R., Tommassen, J. P. M., & de Cock, J. J. P. A. (2005). Lipopolysaccharide transport to the bacterial outer membrane in spheroblasts. Journal of Biological Chemistry, 280, 4504-4509.
Other output
Thibodeaux, B. A., Caballero, A. R., Marquart, M. E., Tommassen, J. P. M., & Lazdunski, A. (2005). Virulence contribution of Pseudomonas aeruginosa elastase and alkaline protease in Pseudomonas putida model of rabbit keraititis. Abstract from Unknown event, Asilomar, USA.
2004
Scholarly publications
Bos, M. P., & Tommassen, J. P. M. (2004). Biogenesis of the Gram-negative bacterial outer membrane. Current Opinion in Microbiology, 7, 610-616.
https://dspace.library.uu.nl/bitstream/handle/1874/12392/bos_04_biogenesis_gram_negative.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/12392/bos_04_biogenesis_gram_negative.pdf?sequence=1
Filloux, A., Bleves, S., van Ulsen, J. P., & Tommassen, J. P. M. (2004). Protein secretion mechanisms in Pseudomonas. In J. L. Ramos (Ed.), Pseudomonas, Vol. 1 (pp. 749-791). Kuwer Academic/Plenum Publishers.
Burghout, P. J., Beckers, F. H. R., de Wit, E., Tommassen-van Boxtel, H. A. M., Cornelis, G. R., Tommassen, J. P. M., & Koster, M. C. (2004). Role of the pilot protein YscW in the biogenesis of the YscC secretin in Yersinia enterocolitica. Journal of Bacteriology, 186, 5366-5375.
Burghout, P. J., Tommassen-van Boxtel, H. A. M., van Gelder, P., Ringler, P., Muller, S. A., Tommassen, J. P. M., & Koster, M. C. (2004). Structure and electrophysiological properties of the YscC secretin from the type III secretion system of Yersinia enterocolitica. Journal of Bacteriology, 186, 4645-4654.
2003
Scholarly publications
Vandeputte-Rutten, L., Bos, M. P., Tommassen, J. P. M., & Gros, P. (2003). Crystal structure of neisserial surface protein A (NspA), a conserved outer membrane protein with vaccine potential. Journal of Biological Chemistry, 278(27), 24825-24830.
https://dspace.library.uu.nl/bitstream/handle/1874/14289/10.1074-jbc.M302803200.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/14289/10.1074-jbc.M302803200.pdf?sequence=1
Other output
Tommassen, J. P. M. (2003). Over bacterien: The good, the bad and the ugly. Universiteit Utrecht.
2002
Scholarly publications
Adams, H., Teertstra, W. R., Koster, M. C., & Tommassen, J. P. M. (2002). PspE (phage-shock protein E) of Escherichia coli is a rhodanese. FEBS Letters, 518, 173-176.
Adams, H., Scotti, P. A., de Cock, J. J. P. A., Luirink, J., & Tommassen, J. P. M. (2002). The presence of a helix breaker in the hydrophobic core of signal sequences of secretory proteins prevents recognition by the signal-recognition particle of Escherichia coli. European Journal of Biochemistry, 269, 5564-5571.
2001
Scholarly publications
Hoffer, S. M., & Tommassen, J. P. M. (2001). The phosphate-binding protein of Escherichia coli is not essential for Pi-regulated expression of the pho regulon. Journal of Bacteriology, 183, 5768-5771.
Hoffer, S. M., Schoondermark, P. F. J., van Veen, H. W., & Tommassen, J. P. M. (2001). Activation by gene amplification of pitB, encoding a third phosphate transporter of Escherichia coli K-12. Journal of Bacteriology, 183, 4659-4663.
van Ulsen, J. P., van Alphen, L., Hopman, C. T. P., van der Ende, A., & Tommassen, J. P. M. (2001). In vivo expression of Neisseria meningitidis proteins homologous to the Haemophilus influenzae Hap and Hia autotransporters. FEMS Immunology and Medical Microbiology, 32, 53-64.
Hoffer, S. M., van Uden, N., & Tommassen, J. P. M. (2001). Expression of the pho regulon interferes with induction of the uhpT gene in Escherichia coli K-12. Archives of Microbiology, 176, 370-376.
Folders, J., Algra, J., Roelofs, M. S., van Loon, L. C., Tommassen, J. P. M., & Bitter, W. (2001). Characterization of Pseudomonas aeruginosa chitinase, a gradually secreted protein. Journal of Bacteriology, 183, 7044-7052.
2000
Scholarly publications
Jansen, C., Wiese, A., Reubsaet, L., Dekker, N., De Cock, H., Seydel, U., & Tommassen, J. (2000). Biochemical and biophysical characterization of in vitro folded outer membrane porin PorA of Neisseria meningitidis. Biochimica et Biophysica Acta-Biomembranes, 1464(2), 284-298. https://doi.org/10.1016/S0005-2736(00)00155-3
Prinz, T. C., & Tommassen, J. P. M. (2000). Association of iron-regulated outer membrane proteins of Neisseria meningitidis with the RmpM (class 4) protein. FEMS Microbiology Letters, 183, 49-53.
Puntervoll, P., Kleivdal, H., Dahl, K. O., Bitter, W., Tommassen, J. P. M., & Jensen, H. B. (2000). The Fusobacterium nucleatum porin FomA possesses the general topology of the non-specific porins. Microbiology, 146, 1437-1445.
El Khattabi, M., van Gelder, P., Bitter, W., & Tommassen, J. P. M. (2000). Role of the lipase-specific foldase of Burkholderia glumae as a steric chaperone. Journal of Biological Chemistry, 275, 26885-26891.
Jansen, C. M., Wiese, A., Reubsaet, L., Dekker, N., de Cock, J. J. P. A., Seydel, U., & Tommassen, J. P. M. (2000). Immunogenicity of in vitro folded outer membrane protein PorA of Neisseria meningitidis. FEMS Immunology and Medical Microbiology, 27, 227-233.
Jansen, C. M., Heutink, M. J. A., Tommassen, J. P. M., & de Cock, J. J. P. A. (2000). The assembly pathway of outer membrane protein PhoE of Escherichia coli. European Journal of Biochemistry, 267, 3792-3800.
Braun, P., Bitter, W., & Tommassen, J. P. M. (2000). Activation of Pseudomonas aeruginosa elastase in Pseudomonas putida by triggering dissociation of the propeptide-enzyme complex. Microbiology, 146, 2565-2572.
1999
Scholarly publications
Pettersson, A., van der Biezen, J., Joosten, V., Hendriksen, J., & Tommassen, J. P. M. (1999). Sequence variability of the meningococcal lactoferrin-binding protein LbpB. Gene, 231, 105-110.
El Khattabi, M., Ockhuysen, C., Bitter, W., Jaeger, K-E., & Tommassen, J. P. M. (1999). Specificity of the lipase-specific foldases of gram-negative bacteria and the role of the membrane anchor. Molecular and General Genetics, 261, 770-776.
Bitter, W., & Tommassen, J. P. M. (1999). Ushers and other doorkeepers. Trends in Microbiology, 7, 4-6.
Dekker, N., Tommassen, J. P. M., & Verheij, H. M. (1999). Bacteriocin release protein triggers dimerization of outer membrane phospholipase A in vivo. Journal of Bacteriology, 181, 3281-3283.
Brok, R., van Gelder, P., Winterhalter, M., Ziese, U., Koster, A. J., de Cock, J. J. P. A., Koster, M. C., & Tommassen, J. P. M. (1999). The C-terminal domain of the Pseudomonas secretin XcpQ forms oligomeric rings with pore activity. Journal of Molecular Biology, 294, 1169-1179.
Wilhelm, S., Tommassen, J. P. M., & Jaeger, K-E. (1999). A novel lipolytic enzyme located in the outer membrane of Pseudomonas aeruginosa. Journal of Bacteriology, 181, 6977-6986.
Other output
Pettersson-Fernholm, A. M., & Tommassen, J. P. M. (1999). Neisseria lactoferrin binding protein. (Patent No. W0-9909176).
Ruelle, J-L., Vinals-Bassols, C., & Tommassen, J. P. M. (1999). In vitro and in vivo assembly of bacterial porins: PorA of Neisseria meningitidis and PhoE of Escherichia coli. (Patent No. WO9964448).
1998
Scholarly publications
Bitter, W., Koster, M., Latijnhouwers, M., de Cock, H., & Tommassen, J. (1998). Formation of oligomeric rings by XcpQ and PilQ, which are involved in protein transport across the outer membrane of Pseudomonas aeruginosa. Molecular Microbiology, 27(1), 209-219.
1997
Scholarly publications
Merck, K. B., de Cock, H., Verheij, H. M., & Tommassen, J. (1997). Topology of the outer membrane phospholipase A of Salmonella typhimurium. Journal of Bacteriology, 179(11), 3443-50.
de Cock, H., Struyvé, M., Kleerebezem, M., van der Krift, T., & Tommassen, J. (1997). Role of the carboxy-terminal phenylalanine in the biogenesis of outer membrane protein PhoE of Escherichia coli K-12. Journal of Molecular Biology, 269(4), 473-8. https://doi.org/10.1006/jmbi.1997.1069
Koster, M., Bitter, W., de Cock, H., Allaoui, A., Cornelis, G. R., & Tommassen, J. (1997). The outer membrane component, YscC, of the Yop secretion machinery of Yersinia enterocolitica forms a ring-shaped multimeric complex. Molecular Microbiology, 26(4), 789-97.
1996
Scholarly publications
Janssen, R., Wauben, MH., & Tommassen, J. (1996). Quaternary structure of a carrier protein influences antigenicity and immunogenicity of an inserted T cell determinant. International Immunology. https://doi.org/10.1093/intimm/8.6.829
de Cock, H., van Blokland, S., & Tommassen, J. (1996). In vitro insertion and assembly of outer membrane protein PhoE of Escherichia coli K-12 into the outer membrane. Role of Triton X-100. Journal of Biological Chemistry, 271(22), 12885-90.
Kleerebezem, M., Heutink, M., de Cock, H., & Tommassen, J. (1996). The qmeA (ts) mutation of Escherichia coli is localized in the fabI gene, which encodes enoyl-ACP reductase. Research in Microbiology, 147(8), 609-13.
de Cock, H., & Tommassen, J. (1996). Lipopolysaccharides and divalent cations are involved in the formation of an assembly-competent intermediate of outer-membrane protein PhoE of E.coli. EMBO Journal, 15(20), 5567-73.
1995
Scholarly publications
Tommassen, J., & de Cock, H. (1995). Export and assembly of outer membrane proteins in e. coli. Advances in Cellular and Molecular Biology of Membranes and Organelles, 4(C), 145-173. https://doi.org/10.1016/S1874-5172(06)80011-8
1994
Scholarly publications
Bitter, W., van Leeuwen, I. S., de Boer, J., Zomer, H. W. M., Koster, M. C., Weisbeek, P. J., & Tommassen, J. (1994). Localization of functional domains in the Escherichia coli coprogen receptor FhuE and the Pseudomonas putida ferric-pseudobactin 358 receptor PupA. Mgg Molecular & General Genetics, 245(6), 694-703. https://doi.org/10.1007/BF00297276
de Groot, A., Heijnen, I., de Cock, H., Filloux, A., & Tommassen, J. (1994). Characterization of type IV pilus genes in plant growth-promoting Pseudomonas putida WCS358. Journal of Bacteriology, 176(3), 642-50.
Van Gelder, P., De Cock, H., & Tommassen, J. (1994). Detergent-induced folding of the outer-membrane protein PhoE, a pore protein induced by phosphate limitation. European Journal of Biochemistry, 226(3), 783-7.
1992
Scholarly publications
Tommassen, J., Struyvé, M., & de Cock, H. (1992). Export and assembly of bacterial outer membrane proteins. Antonie van Leeuwenhoek International Journal of General and Molecular Microbiology, 61(2), 81-5.
de Cock, H., & Tommassen, J. (1992). SecB-binding does not maintain the translocation-competent state of prePhoE. Molecular Microbiology, 6(5), 599-604.
de Cock, H., Overeem, W., & Tommassen, J. (1992). Biogenesis of outer membrane protein PhoE of Escherichia coli. Evidence for multiple SecB-binding sites in the mature portion of the PhoE protein. Journal of Molecular Biology, 224(2), 369-79.
1991
Scholarly publications
de Cock, H., Quaedvlieg, N., Bosch, D., Scholten, M., & Tommassen, J. (1991). Glycine-144 is required for efficient folding of outer membrane protein PhoE of Escherichia coli K12. FEBS Letters, 279(2), 285-8.
de Cock, H., & Tommassen, J. (1991). Conservation of components of the Escherichia coli export machinery in prokaryotes. FEMS Microbiology Letters, 64(2-3), 195-9.
1990
Scholarly publications
de Cock, H., Hekstra, D., & Tommassen, J. (1990). In vitro trimerization of outer membrane protein PhoE. Biochimie, 72(2-3), 177-82.
de Cock, H., Hendriks, R., de Vrije, T., & Tommassen, J. (1990). Assembly of an in vitro synthesized Escherichia coli outer membrane porin into its stable trimeric configuration. Journal of Biological Chemistry, 265(8), 4646-51.
1989
Scholarly publications
Tommassen, J., de Vrije, T., de Cock, H., Bosch, D., & de Kruijff, B. (1989). Involvement of membrane lipids in protein export in Escherichia coli. Journal of cell science. Supplement, 11, 73-83.
de Cock, H., Meeldijk, J., Overduin, P., Verkleij, A., & Tommassen, J. (1989). Membrane biogenesis in Escherichia coli: effects of a secA mutation. Biochimica et Biophysica Acta, 985(3), 313-9.
1988
Scholarly publications
Thole, J. E., Hindersson, P., de Bruyn, J., Cremers, F., van der Zee, J., de Cock, H., Tommassen, J., van Eden, W., & van Embden, J. D. (1988). Antigenic relatedness of a strongly immunogenic 65 kDA mycobacterial protein antigen with a similarly sized ubiquitous bacterial common antigen. Microbial Pathogenesis, 4(1), 71-83.
1987
Scholarly publications
Tommassen, J., Koster, M., & Overduin, P. (1987). Molecular analysis of the promoter region of the Escherichia coli K-12 phoE gene. Identification of an element, upstream from the promoter, required for efficient expression of phoE protein. Journal of Molecular Biology, 198(4), 633-641. https://doi.org/10.1016/0022-2836(87)90206-3