Publications
2025
Scholarly publications
G Valverde, M., Stampa Zamorano, C., Kožinec, D., Benito Zarza, L.
, van Genderen, A. M., Janssen, R., Castilho, M.
, Hrynevich, A., Vermonden, T., Malda, J., de Ruijter, M., Masereeuw, R., & Mihăilă, S. M. (2025).
Thermoforming for Small Feature Replication in Melt Electrowritten Membranes to Model Kidney Proximal Tubule.
Advanced healthcare materials,
14(1), Article 2401800.
https://doi.org/10.1002/adhm.202401800https://research-portal.uu.nl/ws/files/250728734/Adv_Healthcare_Materials_-_2024_-_G_Valverde_-_Thermoforming_for_Small_Feature_Replication_in_Melt_Electrowritten_Membranes_1_.pdf 2024
Scholarly publications
Florczak, S., Ribezzi, D., Falandt, M., Bernal, P., Groessbacher, G.
, Vermonden, T., Malda, J., & Levato, R. (2024).
Multi-material integration in light-based Volumetric Bioprinting: pathways to enhanced precision and complexity in scaffold fabrication. In G. von Freymann, E. Blasco, & D. Chanda (Eds.),
Advanced Fabrication Technologies for Micro/Nano Optics and Photonics XVII Article 128980G (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 12898). SPIE.
https://doi.org/10.1117/12.3008912Ye, S., Marsee, A., van Tienderen, G. S., Rezaeimoghaddam, M., Sheikh, H.
, Samsom, R.-A., de Koning, E. J. P., Fuchs, S., Verstegen, M. M. A., van der Laan, L. J. W., van de Vosse, F.
, Malda, J., Ito, K.
, Spee, B., & Schneeberger, K. (2024).
Accelerated production of human epithelial organoids in a miniaturized spinning bioreactor.
Cell Reports Methods,
4(11), Article 100903.
https://doi.org/10.1016/j.crmeth.2024.100903https://research-portal.uu.nl/ws/files/245914948/1-s2.0-S2667237524002935-main.pdf de Carvalho, A. B. G., Rahimnejad, M., Oliveira, R. L. M. S., Sikder, P., Saavedra, G. S. F. A., Bhaduri, S. B., Gawlitta, D.
, Malda, J., Kaigler, D., Trichês, E. S., & Bottino, M. C. (2024).
Personalized bioceramic grafts for craniomaxillofacial bone regeneration.
International journal of oral science,
16(1), Article 62.
https://doi.org/10.1038/s41368-024-00327-7https://research-portal.uu.nl/ws/files/244978199/s41368-024-00327-7_1_.pdfViola, M., Cedillo-Servin, G.
, van Genderen, A. M., Imhof, I., Vena, P.
, Mihajlovic, M., Piluso, S.
, Malda, J., Vermonden, T., & Castilho, M. (2024).
Microstructured silk fiber scaffolds with enhanced stretchability.
Biomaterials Science,
12(20), 5225-5238.
https://doi.org/10.1039/d4bm00624khttps://research-portal.uu.nl/ws/files/243457694/d4bm00624k.pdf Viola, M., Valverde, M. G., Bernal, P. N.
, van Trijp, J. P., Hak, J.
, Marco, G. D., Neumann, M.
, Schuurmans, C. C. L., van Nostrum, C. F., Masereeuw, R., Mihăilă, S. M., Malda, J., Levato, R., & Vermonden, T. (2024).
Thermal Shrinking of Biopolymeric Hydrogels for High Resolution 3D Printing of Kidney Tubules.
Advanced Functional Materials,
34(46), Article 2406098.
https://doi.org/10.1002/adfm.202406098https://research-portal.uu.nl/ws/files/245912542/Adv_Funct_Materials_-_2024_-_Viola_-_Thermal_Shrinking_of_Biopolymeric_Hydrogels_for_High_Resolution_3D_Printing_of_Kidney.pdf Dubey, N., Rahimnejad, M., Swanson, W. B., Xu, J.
, de Ruijter, M., Malda, J., Squarize, C. H., Castilho, R. M., & Bottino, M. C. (2024).
Integration of Melt Electrowritten Polymeric Scaffolds and Bioprinting for Epithelial Healing via Localized Periostin Delivery.
ACS Macro Letters,
13(8), 959-965.
https://doi.org/10.1021/acsmacrolett.4c00240https://research-portal.uu.nl/ws/files/234252682/dubey-et-al-2024-integration-of-melt-electrowritten-polymeric-scaffolds-and-bioprinting-for-epithelial-healing-via.pdfJanssen, J., Chirico, N., Ainsworth, M. J., Cedillo-Servin, G.
, Viola, M., Dokter, I.
, Vermonden, T., Doevendans, P. A., Serra, M., Voets, I. K.
, Malda, J., Castilho, M., van Laake, L. W., Sluijter, J. P. G., Sampaio-Pinto, V., & van Mil, A. (2024).
Hypothermic and cryogenic preservation of cardiac tissue-engineered constructs.
Biomaterials Science,
12(15), 3866-3881.
https://doi.org/10.1039/d3bm01908jhttps://research-portal.uu.nl/ws/files/233816916/d3bm01908j_1_.pdfWillis, C. R. G., Calvaruso, M., Angeloni, D., Baatout, S., Benchoua, A., Bereiter-Hahn, J., Bottai, D., Buchheim, J.-I., Carnero-Diaz, E., Castiglioni, S., Cavalieri, D., Ceccarelli, G., Chouker, A., Cialdai, F., Ciofani, G., Coppola, G., Cusella, G., Degl'Innocenti, A., Desaphy, J.-F., ... Szewczyk, N. J. (2024).
How to obtain an integrated picture of the molecular networks involved in adaptation to microgravity in different biological systems? npj Microgravity,
10(1), Article 50.
https://doi.org/10.1038/s41526-024-00395-3https://research-portal.uu.nl/ws/files/228248545/s41526-024-00395-3.pdfDavis, T., Tabury, K., Zhu, S., Angeloni, D., Baatout, S., Benchoua, A., Bereiter-Hahn, J., Bottai, D., Buchheim, J.-I., Calvaruso, M., Carnero-Diaz, E., Castiglioni, S., Cavalieri, D., Ceccarelli, G., Choukér, A., Cialdai, F., Ciofani, G., Coppola, G., Cusella, G., ... Monici, M. (2024).
How are cell and tissue structure and function influenced by gravity and what are the gravity perception mechanisms? npj Microgravity,
10(1), Article 16.
https://doi.org/10.1038/s41526-024-00357-9https://research-portal.uu.nl/ws/files/228248452/s41526-024-00357-9_1_.pdfRahimnejad, M., Makkar, H., Dal-Fabbro, R.
, Malda, J., Sriram, G., & Bottino, M. C. (2024).
Biofabrication Strategies for Oral Soft Tissue Regeneration.
Advanced healthcare materials,
13(18), Article 2304537.
https://doi.org/10.1002/adhm.202304537https://research-portal.uu.nl/ws/files/232549954/Adv_Healthcare_Materials_-_2024_-_Rahimnejad_-_Biofabrication_Strategies_for_Oral_Soft_Tissue_Regeneration.pdfBosmans, C., Ginés Rodriguez, N., Karperien, M.
, Malda, J., Moreira Teixeira, L., Levato, R., & Leijten, J. (2024).
Towards single-cell bioprinting: micropatterning tools for organ-on-chip development.
Trends in Biotechnology,
42(6), 739-759.
https://doi.org/10.1016/j.tibtech.2023.11.014https://research-portal.uu.nl/ws/files/227461293/PIIS0167779923003360.pdfRosales, R. M., Mountris, K. A., Oliván-Viguera, A., Pérez-Zabalza, M., Cedillo-Servin, G., Iglesias-García, O.
, Hrynevich, A., Castilho, M.
, Malda, J., Prósper, F., Doblaré, M., Mazo, M. M., & Pueyo, E. (2024).
Experimentally-guided in silico design of engineered heart tissues to improve cardiac electrical function after myocardial infarction.
Computers in Biology and Medicine,
171, 1-13. Article 108044.
https://doi.org/10.1016/j.compbiomed.2024.108044https://dspace.library.uu.nl/bitstream/handle/1874/435892/1-s2.0-S0010482524001288-main.pdf?sequence=1Viola, M., Ainsworth, M. J.
, Mihajlovic, M., Cedillo-Servin, G.
, van Steenbergen, M. J., van Rijen, M.
, de Ruijter, M., Castilho, M.
, Malda, J., & Vermonden, T. (2024).
Covalent Grafting of Functionalized MEW Fibers to Silk Fibroin Hydrogels to Obtain Reinforced Tissue Engineered Constructs.
Biomacromolecules,
25(3), 1563-1577.
https://doi.org/10.1021/acs.biomac.3c01147https://dspace.library.uu.nl/bitstream/handle/1874/436896/viola-et-al-2024-covalent-grafting-of-functionalized-mew-fibers-to-silk-fibroin-hydrogels-to-obtain-reinforced-tissue.pdf?sequence=1 Elkadi, O. A., Abinzano, F., Nippolainen, E., González, O. B.
, Levato, R., Malda, J., & Afara, I. O. (2024).
Non-neotissue constituents as underestimated confounders in the assessment of tissue engineered constructs by near-infrared spectroscopy.
Materials Today Bio,
24, 1-10. Article 100879.
https://doi.org/10.1016/j.mtbio.2023.100879https://dspace.library.uu.nl/bitstream/handle/1874/435439/1-s2.0-S2590006423003393-main.pdf?sequence=1de Ruijter, M.
, Diloksumpan, P., Dokter, I.
, Brommer, H., Smit, I. H., Levato, R., van Weeren, P. R., Castilho, M.
, & Malda, J. (2024).
Orthotopic equine study confirms the pivotal importance of structural reinforcement over the pre-culture of cartilage implants.
Bioengineering and Translational Medicine,
9(1), Article e10614.
https://doi.org/10.1002/btm2.10614https://dspace.library.uu.nl/bitstream/handle/1874/435061/Bioengineering_Transla_Med_-_2023_-_Ruijter_-_Orthotopic_equine_study_confirms_the_pivotal_importance_of_structural.pdf?sequence=1Mancini, I. A. D., Levato, R., Ksiezarczyk, M. M., Castilho, M. D., Chen, M., van Rijen, M. H. P.
, IJsseldijk, L. L., Kik, M., van Weeren, R., & Malda, J. (2024).
Microstructural differences in the osteochondral unit of terrestrial and aquatic mammals.
eLife,
12, Article e80936.
https://doi.org/10.7554/eLife.80936https://dspace.library.uu.nl/bitstream/handle/1874/452483/elife-80936-v2.pdf?sequence=1 Cedillo-Servin, G., Dahri, O., Meneses, J.
, van Duijn, J., Moon, H., Sage, F., Silva, J., Pereira, A., Magalhães, F. D.
, Malda, J., Geijsen, N., Pinto, A. M., & Castilho, M. (2024).
3D Printed Magneto-Active Microfiber Scaffolds for Remote Stimulation and Guided Organization of 3D In Vitro Skeletal Muscle Models.
Small,
20(12), Article 2307178.
https://doi.org/10.1002/smll.202307178https://dspace.library.uu.nl/bitstream/handle/1874/437974/Small_-_2023_-_Cedillo_Servin_-_3D_Printed_Magneto_Active_Microfiber_Scaffolds_for_Remote_Stimulation_and_Guided.pdf?sequence=12023
Scholarly publications
Viola, M., Cedillo-Servin, G.
, van Genderen, A. M., Imhof, I., Vena, P.
, Mihajlovic, M., Piluso, S.
, Malda, J., Vermonden, T., & Castilho, M. (2023).
Microstructured silk-fiber scaffolds with enhanced stretchability. (pp. 1-32). (bioRxiv). bioRxiv.
https://doi.org/10.1101/2023.06.01.542724 Cedillo-Servin, G., Louro, A. F., Gamelas, B., Meliciano, A., Zijl, A., Alves, P. M.
, Malda, J., Serra, M., & Castilho, M. (2023).
Microfiber-reinforced hydrogels prolong the release of human induced pluripotent stem cell-derived extracellular vesicles to promote endothelial migration.
Biomaterials Advances,
155, Article 213692.
https://doi.org/10.1016/j.bioadv.2023.213692https://dspace.library.uu.nl/bitstream/handle/1874/434939/1-s2.0-S2772950823004156-main.pdf?sequence=1Cialdai, F., Brown, A. M., Baumann, C. W., Angeloni, D., Baatout, S., Benchoua, A., Bereiter-Hahn, J., Bottai, D., Buchheim, J.-I., Calvaruso, M., Carnero-Diaz, E., Castiglioni, S., Cavalieri, D., Ceccarelli, G., Choukér, A., Ciofani, G., Coppola, G., Cusella, G., Degl'Innocenti, A., ... Monici, M. (2023).
How do gravity alterations affect animal and human systems at a cellular/tissue level? npj Microgravity,
9(1), Article 84.
https://doi.org/10.1038/s41526-023-00330-yhttps://dspace.library.uu.nl/bitstream/handle/1874/434501/s41526-023-00330-y.pdf?sequence=1Schwab, A., Wesdorp, M. A., Xu, J., Abinzano, F., Loebel, C.
, Falandt, M., Levato, R., Eglin, D., Narcisi, R., Stoddart, M. J.
, Malda, J., Burdick, J. A., D'Este, M., & van Osch, G. J. V. M. (2023).
Modulating design parameters to drive cell invasion into hydrogels for osteochondral tissue formation.
Journal of Orthopaedic Translation,
41, 42-53.
https://doi.org/10.1016/j.jot.2023.07.001https://dspace.library.uu.nl/bitstream/handle/1874/434500/1-s2.0-S2214031X23000487-main.pdf?sequence=1Rikkers, M., Nguyen, H. C., Golafshan, N.
, de Ruijter, M., Levato, R., Vonk, L. A., van Egmond, N., Castilho, M., Custers, R. J. H.
, & Malda, J. (2023).
A gap-filling, regenerative implant for open-wedge osteotomy.
Journal of Cartilage and Joint Preservation,
3(4), 1-10. Article 100117.
https://doi.org/10.1016/j.jcjp.2023.100117https://dspace.library.uu.nl/bitstream/handle/1874/434245/1-s2.0-S2667254523000197-main.pdf?sequence=1Falandt, M., Bernal, P. N., Dudaryeva, O., Florczak, S., Größbacher, G., Schweiger, M., Longoni, A., Greant, C., Assunção, M., Nijssen, O., van Vlierberghe, S.
, Malda, J., Vermonden, T., & Levato, R. (2023).
Spatial-Selective Volumetric 4D Printing and Single-Photon Grafting of Biomolecules within Centimeter-Scale Hydrogels via Tomographic Manufacturing.
Advanced Materials Technologies,
8(15), Article 2300026.
https://doi.org/10.1002/admt.202300026https://dspace.library.uu.nl/bitstream/handle/1874/430342/Adv_Materials_Technologies_-_2023_-_Falandt.pdf?sequence=1 Abbadessa, A., Nuñez Bernal, P., Buttitta, G., Ronca, A., D'Amora, U., Zihlmann, C., Stiefel, N., Ambrosio, L.
, Malda, J., Levato, R., Crecente-Campo, J., & Alonso, M. J. (2023).
Biofunctionalization of 3D printed collagen with bevacizumab-loaded microparticles targeting pathological angiogenesis.
Journal of controlled release : official journal of the Controlled Release Society,
360, 747-758.
https://doi.org/10.1016/j.jconrel.2023.07.017https://dspace.library.uu.nl/bitstream/handle/1874/429995/1-s2.0-S0168365923004443-main.pdf?sequence=1 Galarraga, J. H., Zlotnick, H. M., Locke, R. C., Gupta, S., Fogarty, N. L., Masada, K. M., Stoeckl, B. D., Laforest, L., Castilho, M.
, Malda, J., Levato, R., Carey, J. L., Mauck, R. L., & Burdick, J. A. (2023).
Evaluation of surgical fixation methods for the implantation of melt electrowriting-reinforced hyaluronic acid hydrogel composites in porcine cartilage defects.
International Journal of Bioprinting,
9(5), 493-509. Article 775.
https://doi.org/10.18063/ijb.775https://dspace.library.uu.nl/bitstream/handle/1874/429994/IJB-9-5-775.pdf?sequence=1Van Ombergen, A., Chalupa-Gantner, F., Chansoria, P., Colosimo, B. M., Costantini, M., Domingos, M., Dufour, A., De Maria, C., Groll, J., Jungst, T.
, Levato, R., Malda, J., Margarita, A., Marquette, C., Ovsianikov, A., Petiot, E., Read, S., Surdo, L., Swieszkowski, W., ... Gelinsky, M. (2023).
3D Bioprinting in Microgravity: Opportunities, Challenges, and Possible Applications in Space.
Advanced healthcare materials,
12(23), Article 2300443.
https://doi.org/10.1002/adhm.202300443https://dspace.library.uu.nl/bitstream/handle/1874/431288/Adv_Healthcare_Materials_-_2023_-_Van_Ombergen.pdf?sequence=1Mahmoud, A. H., Han, Y., Dal-Fabbro, R., Daghrery, A., Xu, J., Kaigler, D., Bhaduri, S. B.
, Malda, J., & Bottino, M. C. (2023).
Nanoscale β-TCP-Laden GelMA/PCL Composite Membrane for Guided Bone Regeneration.
ACS applied materials & interfaces,
15(27), 32121–32135.
https://doi.org/10.1021/acsami.3c03059https://dspace.library.uu.nl/bitstream/handle/1874/429392/acsami.3c03059.pdf?sequence=1Ainsworth, M. J., Chirico, N.
, de Ruijter, M., Hrynevich, A., Dokter, I., Sluijter, J. P. G.
, Malda, J., van Mil, A., & Castilho, M. (2023).
Convergence of melt electrowriting and extrusion-based bioprinting for vascular patterning of a myocardial construct.
Biofabrication,
15(3), Article 035025.
https://doi.org/10.1088/1758-5090/ace07fhttps://dspace.library.uu.nl/bitstream/handle/1874/429167/Convergence_of_melt_electrowriting_and_extrusion-based_bioprinting_for_vascular_patterning_of_a_myocardial_construct.pdf?sequence=1Ribezzi, D., Gueye, M., Florczak, S., Dusi, F., de Vos, D.
, Manente, F., Hierholzer, A., Fussenegger, M.
, Caiazzo, M., Blunk, T.
, Malda, J., & Levato, R. (2023).
Shaping Synthetic Multicellular and Complex Multimaterial Tissues via Embedded Extrusion-Volumetric Printing of Microgels.
Advanced Materials,
35(36), Article 2301673.
https://doi.org/10.1002/adma.202301673https://dspace.library.uu.nl/bitstream/handle/1874/430996/Advanced_Materials_-_2023_-_Ribezzi.pdf?sequence=1Moo, E. K., Ebrahimi, M.
, Hrynevich, A., de Ruijter, M., Castilho, M.
, Malda, J., & Korhonen, R. K. (2023).
Load-induced fluid pressurisation in hydrogel systems before and after reinforcement by melt-electrowritten fibrous meshes.
Journal of the Mechanical Behavior of Biomedical Materials,
143, 1-12. Article 105941.
https://doi.org/10.1016/j.jmbbm.2023.105941https://dspace.library.uu.nl/bitstream/handle/1874/429156/1_s2.0_S1751616123002941_main.pdf?sequence=1Größbacher, G., Bartolf-Kopp, M., Gergely, C., Bernal, P. N., Florczak, S., de Ruijter, M., Rodriguez, N. G., Groll, J.
, Malda, J., Jüngst, T.
, & Levato, R. (2023).
Volumetric Printing across Melt Electrowritten Scaffolds Fabricates Multi-Material Living Constructs with Tunable Architecture and Mechanics.
Advanced Materials,
35(32), 1-18. Article 2300756.
https://doi.org/10.1002/adma.202300756https://dspace.library.uu.nl/bitstream/handle/1874/430444/Advanced_Materials_-_2023_-_Gr_bacher.pdf?sequence=1Soliman, B. G., Longoni, A., Wang, M., Li, W., Bernal, P. N., Cianciosi, A., Lindberg, G. C. J.
, Malda, J., Groll, J., Jungst, T.
, Levato, R., Rnjak-Kovacina, J., Woodfield, T. B. F., Zhang, Y. S., & Lim, K. S. (2023).
Programming Delayed Dissolution Into Sacrificial Bioinks For Dynamic Temporal Control of Architecture within 3D-Bioprinted Constructs.
Advanced Functional Materials,
33(8), Article 2210521.
https://doi.org/10.1002/adfm.202210521https://dspace.library.uu.nl/bitstream/handle/1874/427404/Adv_Funct_Materials_2023_Soliman_Programming_Delayed_Dissolution_Into_Sacrificial_Bioinks_For_Dynamic_Temporal.pdf?sequence=1Golafshan, N., Castilho, M., Daghrery, A., Alehosseini, M., van de Kemp, T., Krikonis, K., de Ruijter, M., Dal-Fabbro, R., Dolatshahi-Pirouz, A., Bhaduri, S. B., Bottino, M. C.
, & Malda, J. (2023).
Composite Graded Melt Electrowritten Scaffolds for Regeneration of the Periodontal Ligament-to-Bone Interface.
ACS applied materials & interfaces,
15(10), 12735-12749.
https://doi.org/10.1021/acsami.2c21256https://dspace.library.uu.nl/bitstream/handle/1874/429428/acsami.2c21256.pdf?sequence=1Steverink, J. G., van Tol, F. R., Bruins, S., Smorenburg, A. J.
, Tryfonidou, M. A., Oosterman, B. J., van Dijk, M. R.
, Malda, J., & Verlaan, J.-J. (2023).
Lack of concentration-dependent local toxicity of highly concentrated (5%) versus conventional 0.5% bupivacaine following musculoskeletal surgery in a rat model.
Journal of Experimental Orthopaedics,
10(1), 1-10. Article 21.
https://doi.org/10.1186/s40634-023-00591-2https://dspace.library.uu.nl/bitstream/handle/1874/427557/s40634_023_00591_2.pdf?sequence=1de Silva, L., Bernal, P. N., Rosenberg, A.
, Malda, J., Levato, R., & Gawlitta, D. (2023).
Biofabricating the vascular tree in engineered bone tissue.
Acta Biomaterialia,
156, 250-268.
https://doi.org/10.1016/j.actbio.2022.08.051https://dspace.library.uu.nl/bitstream/handle/1874/431296/1-s2.0-S1742706122005281-main.pdf?sequence=1Daghrery, A., Ferreira, J. A., Xu, J., Golafshan, N., Kaigler, D., Bhaduri, S. B.
, Malda, J., Castilho, M., & Bottino, M. C. (2023).
Tissue-specific melt electrowritten polymeric scaffolds for coordinated regeneration of soft and hard periodontal tissues.
Bioactive Materials,
19, 268-281.
https://doi.org/10.1016/j.bioactmat.2022.04.013https://dspace.library.uu.nl/bitstream/handle/1874/423182/1_s2.0_S2452199X22001827_main.pdf?sequence=1Daghrery, A., Araújo, I. J. D. S., Castilho, M.
, Malda, J., & Bottino, M. C. (2023).
Unveiling the Potential of Melt Electrowriting in Regenerative Dental Medicine.
Acta Biomaterialia,
156, 88-109.
https://doi.org/10.1016/j.actbio.2022.01.010https://dspace.library.uu.nl/bitstream/handle/1874/431762/1-s2.0-S1742706122000101-main.pdf?sequence=12022
Scholarly publications
Hrynevich, A., Ainsworth, M. J.
, van Duijn, J., Malda, J., & Castilho, M. (2022).
ADAPTIVE TOOLPATH G-CODING FOR COMPLEX GEOMETRIES PRODUCED BY MELT ELECTROWRITING FOR THICKER AND MECHANICALLY ROBUST BIOENGINEERED MYOCARDIAL CONSTRUCTS.
Tissue Engineering - Part A.,
28(S1), S449-S449. Article 1600.
https://doi.org/10.1089/ten.tea.2022.29025.abstracts Golafshan, N., Willemsen, K., Weinans, H., van der Wal, B. C. H.
, Malda, J., & Castilho, M. (2022).
A 3D-PRINTED BONE IMPLANT FOR HIP DYSPLASIA TREATMENT: COMBINING SHAPE AND MECHANICAL FUNCTION IN A FULLY RESORBABLE IMPLANT.
Tissue Engineering - Part A.,
28(S1), S440-S440. Article 1566.
https://doi.org/10.1089/ten.tea.2022.29025.abstractsde Ruijter, M., Golafshan, N., Dokter, I., Gkoni, I., Verberne, R.
, van Weeren, R., Brama, P. A. J., Kelly, D. J., Ito, K., Little, P., Pivonka, P.
, Malda, J., & Castilho, M. (2022).
SCALING UP FROM OSTEOCHONDRAL PLUG TO PATIENT-SPECIFIC CONDYLE RESURFACING: FABRICATION, IN VITRO CHARACTERIZATION, AND MECHANICAL CHARACTERIZATION UNDER PHYSIOLOGICAL CONDITIONS OF CLINICALLY RELEVANT OSTEOCHONDRAL IMPLANTS.
Tissue Engineering - Part A.,
28(S1), S290-S290. Article 1039.
https://doi.org/10.1089/ten.tea.2022.29025.abstractsBernal, P. N., Delrot, P., Loterie, D.
, Li, Y., Malda, J., Moser, C.
, & Levato, R. (2022).
HIGH-SPEED VOLUMETRIC BIOPRINTING APPROACH FOR BIOFABRICATION OF COMPLEX LIVING TISSUE STRUCTURES.
Tissue Engineering - Part A.,
28(S1), S150-S150. Article 539.
https://doi.org/10.1089/ten.tea.2022.29025.abstractsAbinzano, F., Lim, K., Bernal, P. N., Roca, P. A., Sanchez, A. A., Otto, I., Matsusaki, M., Woodfield, T.
, Malda, J., & Levato, R. (2022).
DUAL-FUNCTIONALIZED VISIBLE-LIGHT RESPONSIVE GELATIN BIOINK AS CARTILAGE BINDING GLUE AND MATRIX FOR 3D CHONDRAL REGENERATION.
Tissue Engineering - Part A.,
28(S1), S222-S223. Article 790.
https://doi.org/10.1089/ten.tea.2022.29025.abstractsViola, M., Piluso, S.
, Mihajlovic, M., Malda, J., Castilho, M.
, & Vermonden, T. (2022).
SILK-BASED MATERIALS TO CREATE HIGH RESOLUTION THREE-DIMENSIONAL STRUCTURES USING ELECTROHYDRODYNAMIC PRINTING.
Tissue Engineering - Part A.,
28(S1), S110-S110. Article 400.
https://doi.org/10.1089/ten.tea.2022.29025.abstractshttps://dspace.library.uu.nl/bitstream/handle/1874/423390/Pages_from_ten.tea.2022.29025.abstracts3.pdf?sequence=1 van Mil, A., Castilho, M., Chirico, N., Ainsworth, M. J., Dokter, I., Maas, R. G. C., Buikema, J. W.
, Malda, J., & Sluijter, J. P. G. (2022).
NEXT GENERATION BIOENGINEERED HUMAN MYOCARDIUM.
Tissue Engineering - Part A.,
28(S1), S430-S431. Article 1534.
https://doi.org/10.1089/ten.tea.2022.29025.abstractsOtto, I. A., Bernal, P. N., Rikkers, M., Rijen, M. H. P. V.
, Mensinga, A., Kon, M., Breugem, C. C.
, Levato, R., & Malda, J. (2022).
Human adult, pediatric and microtia auricular cartilage harbor fibronectin-adhering progenitor cells with regenerative ear reconstruction potential.
iScience,
25(9), 1-20. Article 104979.
https://doi.org/10.1016/j.isci.2022.104979https://dspace.library.uu.nl/bitstream/handle/1874/423388/PIIS2589004222012512.pdf?sequence=1Mancini, I. A. D., Levato, R., Castilho, M., Chen, M., Rijen, M. H. P. V.
, IJsseldijk, L. L., Kik, M., Weeren, P. R. V., & Malda, J. (2022).
Nature’s design of the osteochondral unit: microstructural differences between terrestrial and aquatic mammals.
https://doi.org/10.1101/2022.06.09.495440 Steverink, J. G., van Tol, F. R., Oosterman, B. J.
, Vermonden, T., Verlaan, J.-J.
, Malda, J., & Piluso, S. (2022).
Robust gelatin hydrogels for local sustained release of bupivacaine following spinal surgery.
Acta Biomaterialia,
146, 145-158.
https://doi.org/10.1016/j.actbio.2022.05.007https://dspace.library.uu.nl/bitstream/handle/1874/421917/1_s2.0_S1742706122002768_main.pdf?sequence=1Terpstra, M. L., Li, J.
, Mensinga, A., de Ruijter, M., van Rijen, M. H. P., Androulidakis, C., Galiotis, C., Papantoniou, I., Matsusaki, M.
, Malda, J., & Levato, R. (2022).
Bioink with cartilage-derived extracellular matrix microfibers enables spatial control of vascular capillary formation in bioprinted constructs.
Biofabrication,
14(3), 1-20. Article 034104.
https://doi.org/10.1088/1758-5090/ac6282https://dspace.library.uu.nl/bitstream/handle/1874/421324/Terpstra_2022_Biofabrication_14_034104.pdf?sequence=1Mihajlovic, M., Rikkers, M.
, Mihajlovic, M., Viola, M., Schuiringa, G.
, Ilochonwu, B. C., Masereeuw, R., Vonk, L.
, Malda, J., Ito, K.
, & Vermonden, T. (2022).
Viscoelastic Chondroitin Sulfate and Hyaluronic Acid Double-Network Hydrogels with Reversible Cross-Links.
Biomacromolecules,
23(3), 1350-1365.
https://doi.org/10.1021/acs.biomac.1c01583https://dspace.library.uu.nl/bitstream/handle/1874/424724/acs.biomac.1c01583.pdf?sequence=1 Bernal, P. N.
, Bouwmeester, M., Madrid-Wolff, J.
, Falandt, M., Florczak, S., Rodriguez, N. G.
, Li, Y., Größbacher, G.
, Samsom, R.-A., van Wolferen, M., van der Laan, L., Delrot, P., Loterie, D.
, Malda, J., Moser, C.
, Spee, B., & Levato, R. (2022).
Volumetric Bioprinting of Organoids and Optically Tuned Hydrogels to Build Liver-Like Metabolic Biofactories.
Advanced Materials,
34(15), 1-16. Article 2110054.
https://doi.org/10.1002/adma.202110054https://dspace.library.uu.nl/bitstream/handle/1874/420374/Advanced_Materials_2022_Bernal_Volumetric_Bioprinting_of_Organoids_and_Optically_Tuned_Hydrogels_to_Build_Liver_Like.pdf?sequence=1Rikkers, M., Korpershoek, J. V.
, Levato, R., Malda, J., & Vonk, L. A. (2022).
The clinical potential of articular cartilage-derived progenitor cells: a systematic review.
npj Regenerative Medicine,
7(1), 1-20. Article 2.
https://doi.org/10.1038/s41536-021-00203-6https://dspace.library.uu.nl/bitstream/handle/1874/419151/s41536_021_00203_6.pdf?sequence=1Galarraga, J. H., Locke, R. C., Witherel, C. E., Stoeckl, B. D., Castilho, M., Mauck, R. L.
, Malda, J., Levato, R., & Burdick, J. A. (2022).
Fabrication of MSC-laden composites of hyaluronic acid hydrogels reinforced with MEW scaffolds for cartilage repair.
Biofabrication,
14(1), 1-16. Article 014106.
https://doi.org/10.1088/1758-5090/ac3acbhttps://dspace.library.uu.nl/bitstream/handle/1874/413900/Galarraga_2022_Biofabrication_14_014106.pdf?sequence=1Aytac, Z., Dubey, N., Daghrery, A., Ferreira, J. A., Araújo, I. J. D. S., Castilho, M.
, Malda, J., & Bottino, M. C. (2022).
Innovations in craniofacial bone and periodontal tissue engineering – from electrospinning to converged biofabrication.
International Materials Reviews,
67(4), 347-384.
https://doi.org/10.1080/09506608.2021.1946236https://dspace.library.uu.nl/bitstream/handle/1874/431668/Innovations_in_craniofacial_bone_and_periodontal_tissue_engineering_from_electrospinning_to_conver.pdf?sequence=1Saukko, A. E. A., Sarin, J. K., Nykänen, O., Nissi, M. J.
, te Moller, N. C. R., Weinans, H.
, Mancini, I. A. D., Visser, J., Brommer, H., van Weeren, P. R., Malda, J., Grinstaff, M. W., & Töyräs, J. (2022).
Dual-contrast computed tomography enables detection of equine posttraumatic osteoarthritis in vitro.
Journal of Orthopaedic Research,
40(3), 703-711.
https://doi.org/10.1002/jor.25066https://dspace.library.uu.nl/bitstream/handle/1874/431692/Journal_Orthopaedic_Research_-_2021_-_Saukko.pdf?sequence=12021
Scholarly publications
Diloksumpan, P., Abinzano, F.
, Ruijter, M. D., Mensinga, A., Plomp, S., Khan, I.
, Brommer, H., Smit, I., Castilho, M. D.
, Weeren, P. R. V., Malda, J., & Levato, R. (2021).
The Complexity of Joint Regeneration: How an Advanced Implant could Fail by Its In Vivo Proven Bone Component.
Journal of Trial and Error,
2(1), 1-20.
https://doi.org/10.36850/e3https://research-portal.uu.nl/ws/files/233040674/01646342620889.pdf Rikkers, M., Dijkstra, K., Terhaard, B. F., Admiraal, J.
, Levato, R., Malda, J., & Vonk, L. A. (2021).
Response.
Cartilage,
13(1_suppl), 1824S-1826S.
https://doi.org/10.1177/1947603521989486https://dspace.library.uu.nl/bitstream/handle/1874/420588/1947603521989486.pdf?sequence=1Abinzano, F.
, Diloksumpan, P., Ruijter, M. D.
, Mensinga, A., Plomp, S., Khan, I. M.
, Brommer, H., Smit, I., Castilho, M.
, van Weeren, R., Malda, J., & Levato, R. (2021).
Building on established technology is no guarantee for success: challenges with the in vivo evaluation of an osteochondral implant based on a proven bone component. Abstract from Conference of the European Society for Biomaterials.
https://eventclass.org/contxt_esb2021/scientific/online-program/session?s=68Zhang, Y. S., Haghiashtiani, G., Hübscher, T., Kelly, D. J., Lee, J. M., Lutolf, M., McAlpine, M. C., Yeong, W. Y., Zenobi-Wong, M.
, & Malda, J. (2021).
3D extrusion bioprinting.
Nature Reviews Methods Primers,
1(1), 1-20. Article 75.
https://doi.org/10.1038/s43586-021-00073-8https://research-portal.uu.nl/ws/files/233446588/s43586-021-00073-8.pdfRikkers, M., Korpershoek, J. V.
, Levato, R., Malda, J., & Vonk, L. A. (2021).
Progenitor Cells in Healthy and Osteoarthritic Human Cartilage Have Extensive Culture Expansion Capacity while Retaining Chondrogenic Properties.
Cartilage,
13(2_suppl), 129S-142S.
https://doi.org/10.1177/19476035211059600https://dspace.library.uu.nl/bitstream/handle/1874/416211/19476035211059600.pdf?sequence=1Levato, R., Lim, K. S., Li, W., Asua, A. U., Peña, L. B., Wang, M.
, Falandt, M., Bernal, P. N., Gawlitta, D., Zhang, Y. S., Woodfield, T. B. F.
, & Malda, J. (2021).
High-resolution lithographic biofabrication of hydrogels with complex microchannels from low-temperature-soluble gelatin bioresins.
Materials Today Bio,
12, 1-13. Article 100162.
https://doi.org/10.1016/j.mtbio.2021.100162https://dspace.library.uu.nl/bitstream/handle/1874/413899/1_s2.0_S2590006421000703_main.pdf?sequence=1 Korpershoek, J. V., Ruijter, M. D., Terhaard, B. F., Hagmeijer, M. H., Saris, D. B. F., Castilho, M.
, Malda, J., & Vonk, L. A. (2021).
Potential of Melt Electrowritten Scaffolds Seeded with Meniscus Cells and Mesenchymal Stromal Cells.
International Journal of Molecular Sciences,
22(20), 1-16. Article 11200.
https://doi.org/10.3390/ijms222011200https://dspace.library.uu.nl/bitstream/handle/1874/413423/ijms_22_11200_v2.pdf?sequence=1Bouwmeester, M. C., Bernal, P. N.
, Oosterhoff, L. A., van Wolferen, M., Lehmann, V., Vermaas, M., Buchholz, M.-B., Peiffer, Q.
, Malda, J., van der Laan, L. J. W.
, Kramer, N. I., Schneeberger, K., Levato, R., & Spee, B. (2021).
Bioprinting of Human Liver-derived Epithelial Organoids for Toxicity Studies.
Macromolecular Bioscience,
21(12), 1-10. Article 2100327.
https://doi.org/10.1002/mabi.202100327https://dspace.library.uu.nl/bitstream/handle/1874/418931/Macromolecular_Bioscience_2021_Bouwmeester_Bioprinting_of_Human_Liver_Derived_Epithelial_Organoids_for_Toxicity.pdf?sequence=1 Golafshan, N., Willemsen, K., Kadumudi, F. B., Vorndran, E., Dolatshahi-Pirouz, A., Weinans, H., van der Wal, B. C. H.
, Malda, J., & Castilho, M. (2021).
3D-Printed Regenerative Magnesium Phosphate Implant Ensures Stability and Restoration of Hip Dysplasia.
Advanced healthcare materials,
10(21), 1-12. Article 2101051.
https://doi.org/10.1002/adhm.202101051https://dspace.library.uu.nl/bitstream/handle/1874/418930/Adv_Healthcare_Materials_2021_Golafshan_3D_Printed_Regenerative_Magnesium_Phosphate_Implant_Ensures_Stability_and.pdf?sequence=1Viola, M., Piluso, S., Groll, J.
, Vermonden, T., Malda, J., & Castilho, M. (2021).
The Importance of Interfaces in Multi-Material Biofabricated Tissue Structures.
Advanced healthcare materials,
10(21), 1-19. Article 2101021.
https://doi.org/10.1002/adhm.202101021https://dspace.library.uu.nl/bitstream/handle/1874/418918/Adv_Healthcare_Materials_2021_Viola_The_Importance_of_Interfaces_in_Multi_Material_Biofabricated_Tissue_Structures.pdf?sequence=1 Daghrery, A., Ferreira, J. A., de Souza Araújo, I. J., Clarkson, B. H., Eckert, G. J., Bhaduri, S. B.
, Malda, J., & Bottino, M. C. (2021).
A Highly Ordered, Nanostructured Fluorinated CaP-Coated Melt Electrowritten Scaffold for Periodontal Tissue Regeneration.
Advanced healthcare materials,
10(21), 1-19. Article 2101152.
https://doi.org/10.1002/adhm.202101152https://dspace.library.uu.nl/bitstream/handle/1874/418910/Adv_Healthcare_Materials_2021_Daghrery_A_Highly_Ordered_Nanostructured_Fluorinated_CaP_Coated_Melt_Electrowritten.pdf?sequence=1Pouran, B.
, Raoof, A., de Winter, D. A. M., Arbabi, V., Bleys, R. L. A. W., Beekman, F. J., Zadpoor, A. A.
, Malda, J., & Weinans, H. (2021).
Topographic features of nano-pores within the osteochondral interface and their effects on transport properties -a 3D imaging and modeling study.
Journal of Biomechanics,
123, 1-8. Article 110504.
https://doi.org/10.1016/j.jbiomech.2021.110504https://dspace.library.uu.nl/bitstream/handle/1874/412350/1_s2.0_S0021929021002852_main.pdf?sequence=1Otto, I. A., Capendale, P. E., Garcia, J. P., de Ruijter, M., van Doremalen, R. F. M., Castilho, M., Lawson, T., Grinstaff, M. W., Breugem, C. C., Kon, M.
, Levato, R., & Malda, J. (2021).
Biofabrication of a shape-stable auricular structure for the reconstruction of ear deformities.
Materials Today Bio,
9, 1-11. Article 100094.
https://doi.org/10.1016/j.mtbio.2021.100094https://dspace.library.uu.nl/bitstream/handle/1874/411725/1_s2.0_S2590006421000028_main.pdf?sequence=1van Genderen, A. M., Jansen, K., Kristen, M.
, van Duijn, J. H., Li, Y.
, Schuurmans, C. C. L., Malda, J., Vermonden, T., Jansen, J., Masereeuw, R., & Castilho, M. (2021).
Topographic Guidance in Melt-Electrowritten Tubular Scaffolds Enhances Engineered Kidney Tubule Performance.
Frontiers in Bioengineering and Biotechnology,
8, 1-14. Article 617364.
https://doi.org/10.3389/fbioe.2020.617364https://dspace.library.uu.nl/bitstream/handle/1874/411350/fbioe_08_617364.pdf?sequence=1 Castilho, M.
, Levato, R., Bernal, P. N., de Ruijter, M., Sheng, C. Y.
, van Duijn, J., Piluso, S., Ito, K.
, & Malda, J. (2021).
Hydrogel-Based Bioinks for Cell Electrowriting of Well-Organized Living Structures with Micrometer-Scale Resolution.
Biomacromolecules,
22(2), 855-866.
https://doi.org/10.1021/acs.biomac.0c01577https://dspace.library.uu.nl/bitstream/handle/1874/410689/acs.biomac.0c01577.pdf?sequence=1Rikkers, M., Dijkstra, K., Terhaard, B. F., Admiraal, J.
, Levato, R., Malda, J., & Vonk, L. A. (2021).
Platelet-Rich Plasma Does Not Inhibit Inflammation or Promote Regeneration in Human Osteoarthritic ChondrocytesIn VitroDespite Increased Proliferation.
Cartilage,
13(2_SUPPL), 991S-1003S.
https://doi.org/10.1177/1947603520961162https://dspace.library.uu.nl/bitstream/handle/1874/429124/rikkers-et-al-2020-platelet-rich-plasma-does-not-inhibit-inflammation-or-promote-regeneration-in-human-osteoarthritic.pdf?sequence=1Kajabi, A. W., Casula, V., Sarin, J. K., Ketola, J. H., Nykänen, O.
, Te Moller, N. C. R., Mancini, I. A. D., Visser, J., Brommer, H., René van Weeren, P.
, Malda, J., Töyräs, J., Nieminen, M. T., & Nissi, M. J. (2021).
Evaluation of articular cartilage with quantitative MRI in an equine model of post-traumatic osteoarthritis.
Journal of Orthopaedic Research,
39(1), 63-73.
https://doi.org/10.1002/jor.24780https://dspace.library.uu.nl/bitstream/handle/1874/432488/Journal_Orthopaedic_Research_-_2020_-_Kajabi_-_Evaluation_of_articular_cartilage_with_quantitative_MRI_in_an_equine_model.pdf?sequence=12020
Scholarly publications
Rikkers, M., Levato, R., Malda, J., & Vonk, L. (2020). Platelet Lysate is Beneficial for Chondrocyte Expansion but Ineffective in 3d Culture. Osteoarthritis and Cartilage, 28, S525-S526.
Rikkers, M., Korpershoek, J. V., van der Leij, S., Levato, R., Malda, J., & Vonk, L. A. (2020). Progenitor Cells From Healthy and Osteoarthritic Human Cartilage Show Potential for One-stage Repair Treatment. Osteoarthritis and Cartilage, 28, S516-S517.
Van Velthoven, M. J. J., Ramadan, R., Zügel, F. S.
, Klotz, B. J., Gawlitta, D., Costa, P. F.
, Malda, J., Castilho, M. D., De Kort, L. M. O., & De Graaf, P. (2020).
Gel Casting as an Approach for Tissue Engineering of Multilayered Tubular Structures.
Tissue Engineering - Part C: Methods,
26(3), 190-198.
https://doi.org/10.1089/ten.tec.2019.0280https://research-portal.uu.nl/ws/files/235529727/van-velthoven-et-al-2020-gel-casting-as-an-approach-for-tissue-engineering-of-multilayered-tubular-structures.pdfCastilho, M., Golafshan, N., Vorndran, E., Gbureck, U., Brommer, H., van Weeren, R., & Malda, J. (2020). 3D printed tough magnesium phosphate-based implants induce bone regeneration in an equine defect model. Journal of Bone and Mineral Research, 35, 71-71.
Safari, N., Golafshan, N., Kharaziha, M., Toroghinejad, M. R.
, Utomo, L., Malda, J., & Castilho, M. (2020).
Stable and Antibacterial Magnesium-Graphene Nanocomposite-Based Implants for Bone Repair.
ACS Biomaterials Science and Engineering,
6(11), 6253-6262.
https://doi.org/10.1021/acsbiomaterials.0c00613https://dspace.library.uu.nl/bitstream/handle/1874/410213/acsbiomaterials.0c00613.pdf?sequence=1Augurio, A., Cortelletti, P., Tognato, R., Rios, A.
, Levato, R., Malda, J., Alini, M., Eglin, D., Giancane, G., Speghini, A., & Serra, T. (2020).
A Multifunctional Nanocomposite Hydrogel for Endoscopic Tracking and Manipulation.
Advanced Intelligent Systems,
2(3), Article 1900105.
https://doi.org/10.1002/aisy.201900105https://dspace.library.uu.nl/bitstream/handle/1874/410176/aisy.201900105.pdf?sequence=1Zhou, L., Gjvm, V. O.
, Malda, J., Stoddart, M. J., Lai, Y., Richards, R. G., Ki-wai Ho, K., & Qin, L. (2020).
Innovative Tissue-Engineered Strategies for Osteochondral Defect Repair and Regeneration: Current Progress and Challenges.
Advanced healthcare materials, Article 2001008.
https://doi.org/10.1002/adhm.202001008https://dspace.library.uu.nl/bitstream/handle/1874/409718/adhm.202001008.pdf?sequence=1Wu, D. J., Vonk, N. H., Lamers, B. A. G., Castilho, M.
, Malda, J., Hoefnagels, J. P. M., & Dankers, P. Y. W. (2020).
Anisotropic hygro-expansion in hydrogel fibers owing to uniting 3D electrowriting and supramolecular polymer assembly.
European Polymer Journal,
141, Article 110099.
https://doi.org/10.1016/j.eurpolymj.2020.110099https://dspace.library.uu.nl/bitstream/handle/1874/409717/1_s2.0_S0014305720318139_main.pdf?sequence=1Schmidt, S., Abinzano, F.
, Mensinga, A., Teßmar, J., Groll, J.
, Malda, J., Levato, R., & Blunk, T. (2020).
Differential production of cartilage ECM in 3D agarose constructs by equine articular cartilage progenitor cells and mesenchymal stromal cells.
International Journal of Molecular Sciences,
21(19), 1-19. Article 7071.
https://doi.org/10.3390/ijms21197071https://dspace.library.uu.nl/bitstream/handle/1874/409716/ijms_21_07071_v2.pdf?sequence=1Groen, W. M. G. A. C., Utomo, L., Castilho, M., Gawlitta, D.
, Malda, J., van Weeren, P. R., Levato, R., & Korthagen, N. M. (2020).
Impact of endotoxins in gelatine hydrogels on chondrogenic differentiation and inflammatory cytokine secretion in vitro.
International Journal of Molecular Sciences,
21(22), 1-17. Article 8571.
https://doi.org/10.3390/ijms21228571https://dspace.library.uu.nl/bitstream/handle/1874/409715/ijms_21_08571.pdf?sequence=1 Cui, X., Soliman, B. G., Alcala-Orozco, C. R., Li, J., Vis, M. A. M., Santos, M., Wise, S. G.
, Levato, R., Malda, J., Woodfield, T. B. F., Rnjak-Kovacina, J., & Lim, K. S. (2020).
Correction to: Rapid Photocrosslinking of Silk Hydrogels with High Cell Density and Enhanced Shape Fidelity (Adv. Healthcare Mater, (2020), 9, (1901667), 10.1002/adhm.201901667).
Advanced healthcare materials,
9(22), 1. Article 2001801.
https://doi.org/10.1002/adhm.202001801https://dspace.library.uu.nl/bitstream/handle/1874/409714/adhm.202001801.pdf?sequence=1Piluso, S.
, Flores Gomez, D., Dokter, I., Moreira Texeira, L.
, Li, Y., Leijten, J.
, van Weeren, R., Vermonden, T., Karperien, M.
, & Malda, J. (2020).
Rapid and cytocompatible cell-laden silk hydrogel formation via riboflavin-mediated crosslinking.
Journal of Materials Chemistry B,
8(41), 9566-9575.
https://doi.org/10.1039/d0tb01731khttps://dspace.library.uu.nl/bitstream/handle/1874/428100/d0tb01731k.pdf?sequence=1Schneeberger, K., Bouwmeester, M., Levato, R., Kramer, N., Malda, J., & Spee, B. (2020).
BIOFABRICATION OF LIVER CONSTRUCTS FOR DRUG TOXICITY STUDIES.
Drug Metabolism and Pharmacokinetics,
35(1), S8-S8.
https://doi.org/10.1016/j.dmpk.2020.04.295 Albers, H. J., Linssen, J. E. A., Costa, P. F., Middelkamp, H. H. T., van der Hout, L., Malda, J., Passier, R., van den Berg, A., & van der Meer, A. D. (2020). Using 3D-printing to fabricate a microfluidic vascular model to mimic arterial thrombosis. In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 (pp. 1070-1071). Chemical and Biological Microsystems Society.
Peiffer, Q. C., de Ruijter, M.
, van Duijn, J., Crottet, D., Dominic, E.
, Malda, J., & Castilho, M. (2020).
Melt electrowriting onto anatomically relevant biodegradable substrates: Resurfacing a diarthrodial joint.
Materials and Design,
195, 1-9. Article 109025.
https://doi.org/10.1016/j.matdes.2020.109025https://dspace.library.uu.nl/bitstream/handle/1874/408783/1_s2.0_S0264127520305608_main.pdf?sequence=1Jahanmard, F.
, Croes, M., Castilho, M., Majed, A.
, Steenbergen, M. J., Lietaert, K., Vogely, H. C., van der Wal, B. C. H.
, Stapels, D. A. C., Malda, J., Vermonden, T., & Amin Yavari, S. (2020).
Bactericidal coating to prevent early and delayed implant-related infections.
Journal of controlled release : official journal of the Controlled Release Society,
326, 38-52.
https://doi.org/10.1016/j.jconrel.2020.06.014https://dspace.library.uu.nl/bitstream/handle/1874/408782/1_s2.0_S0168365920303485_main.pdf?sequence=1Otto, I. A., Simone, A.
, Malda, J., Kon, M., & Breugem, C. C. (2020).
Engaging stakeholders in bioprinting research: Views and concerns of microtia patients' parents on bioprinted auricular cartilage.
Journal of Plastic, Reconstructive and Aesthetic Surgery,
73(12), 2239-2260.
https://doi.org/10.1016/j.bjps.2020.05.066https://dspace.library.uu.nl/bitstream/handle/1874/408781/1_s2.0_S1748681520302461_main.pdf?sequence=1Dubey, N., Ferreira, J. A., Daghrery, A., Aytac, Z.
, Malda, J., Bhaduri, S. B., & Bottino, M. C. (2020).
Highly tunable bioactive fiber-reinforced hydrogel for guided bone regeneration.
Acta Biomaterialia,
113, 164-176.
https://doi.org/10.1016/j.actbio.2020.06.011https://dspace.library.uu.nl/bitstream/handle/1874/408780/1_s2.0_S1742706120303329_main.pdf?sequence=1Castilho, M., de Ruijter, M., Beirne, S., Villette, C. C., Ito, K., Wallace, G. G.
, & Malda, J. (2020).
Multitechnology Biofabrication: A New Approach for the Manufacturing of Functional Tissue Structures? Trends in Biotechnology,
38(12), 1316-1328.
https://doi.org/10.1016/j.tibtech.2020.04.014https://dspace.library.uu.nl/bitstream/handle/1874/408778/1_s2.0_S0167779920301190_main.pdf?sequence=1Schwab, A.
, Levato, R., D'Este, M., Piluso, S., Eglin, D.
, & Malda, J. (2020).
Printability and Shape Fidelity of Bioinks in 3D Bioprinting.
Chemical Reviews,
120(19), 11028-11055.
https://doi.org/10.1021/acs.chemrev.0c00084https://dspace.library.uu.nl/bitstream/handle/1874/408777/acs.chemrev.0c00084.pdf?sequence=1Golafshan, N., Vorndran, E., Zaharievski, S.
, Brommer, H., Kadumudi, F. B., Dolatshahi-Pirouz, A., Gbureck, U.
, van Weeren, R., Castilho, M.
, & Malda, J. (2020).
Tough magnesium phosphate-based 3D-printed implants induce bone regeneration in an equine defect model.
Biomaterials,
261, Article 120302.
https://doi.org/10.1016/j.biomaterials.2020.120302https://dspace.library.uu.nl/bitstream/handle/1874/408775/1_s2.0_S0142961220305482_main.pdf?sequence=1Langerak, N.
, Ahmed, H. M. M., Li, Y.
, Middel, I. R., Eslami Amirabadi, H., Malda, J., Masereeuw, R., & van Roij, R. (2020).
A Theoretical and Experimental Study to Optimize Cell Differentiation in a Novel Intestinal Chip.
Frontiers in Bioengineering and Biotechnology,
8, Article 763.
https://doi.org/10.3389/fbioe.2020.00763https://dspace.library.uu.nl/bitstream/handle/1874/408705/fbioe_08_00763.pdf?sequence=1Mancini, I. A. D., Schmidt, S.
, Brommer, H., Pouran, B., Schäfer, S., Tessmar, J.
, Mensinga, A., van Rijen, M. H. P., Groll, J., Blunk, T.
, Levato, R., Malda, J., & van Weeren, P. R. (2020).
A composite hydrogel-3D printed thermoplast osteochondral anchor as an example for a zonal approach to cartilage repair: in vivo performance in a long-term equine model.
Biofabrication,
12, Article 035028.
https://doi.org/10.1088/1758-5090/ab94cehttps://dspace.library.uu.nl/bitstream/handle/1874/432526/Mancini_2020_Biofabrication_12_035028.pdf?sequence=1 Qiu, B., Bessler, N., Figler, K., Buchholz, M. B., Rios, A. C.
, Malda, J., Levato, R., & Caiazzo, M. (2020).
Bioprinting Neural Systems to Model Central Nervous System Diseases.
Advanced Functional Materials,
30(44), Article 1910250.
https://doi.org/10.1002/adfm.201910250https://dspace.library.uu.nl/bitstream/handle/1874/432455/Adv_Funct_Materials_-_2020_-_Qiu_-_Bioprinting_Neural_Systems_to_Model_Central_Nervous_System_Diseases.pdf?sequence=1 Groen, W. M., Levato, R., Malda, J., van Weeren, P. R., & Korthagen, N. M. (2020).
In vitro response of mesenchymal stromal cells and peripheral blood mononuclear cells to high- and low-endotoxin gelatine methacryloyl hydrogels. S523-S524.
https://doi.org/10.1016/j.joca.2020.02.823 Levato, R., Jungst, T., Scheuring, R. G., Blunk, T., Groll, J.
, & Malda, J. (2020).
From Shape to Function: The Next Step in Bioprinting.
Advanced Materials,
32(12), Article 1906423.
https://doi.org/10.1002/adma.201906423https://dspace.library.uu.nl/bitstream/handle/1874/408143/adma.201906423.pdf?sequence=1 Diloksumpan, P., Bolaños, R. V.
, Cokelaere, S., Pouran, B.
, de Grauw, J., van Rijen, M.
, van Weeren, R., Levato, R., & Malda, J. (2020).
Orthotopic Bone Regeneration within 3D Printed Bioceramic Scaffolds with Region-Dependent Porosity Gradients in an Equine Model.
Advanced healthcare materials,
9(10), 1-11. Article e1901807.
https://doi.org/10.1002/adhm.201901807https://dspace.library.uu.nl/bitstream/handle/1874/408142/adhm.201901807.pdf?sequence=1 Lim, K. S., Abinzano, F., Bernal, P. N., Albillos Sanchez, A., Atienza-Roca, P., Otto, I. A., Peiffer, Q. C., Matsusaki, M., Woodfield, T. B. F.
, Malda, J., & Levato, R. (2020).
One-Step Photoactivation of a Dual-Functionalized Bioink as Cell Carrier and Cartilage-Binding Glue for Chondral Regeneration.
Advanced healthcare materials,
9(15), Article 1901792.
https://doi.org/10.1002/adhm.201901792https://dspace.library.uu.nl/bitstream/handle/1874/408141/adhm.201901792.pdf?sequence=1Dubey, N., Ferreira, J.
, Malda, J., Bhaduri, S. B., & Bottino, M. C. (2020).
Extracellular Matrix/Amorphous Magnesium Phosphate Bioink for 3D Bioprinting of Craniomaxillofacial Bone Tissue.
ACS applied materials & interfaces,
12(21), 23752–23763.
https://doi.org/10.1021/acsami.0c05311https://dspace.library.uu.nl/bitstream/handle/1874/408140/acsami.0c05311.pdf?sequence=1Morgan, B., Bauza-Mayol, G., Gardner, O., Zhang, Y., Levato, R., Archer, C.
, van Weeren, R., Malda, J., Conlan, R. S., Francis, L., & Khan, I. (2020).
BMP9 is a potent chondrogenic and morphogenic factor for articular cartilage-derived chondroprogenitors.
Stem Cells and Development,
29(14), 882-894.
https://doi.org/10.1089/scd.2019.0209https://dspace.library.uu.nl/bitstream/handle/1874/432327/scd.2019.0209.pdf?sequence=1Bolaños, R. V., Castilho, M.
, de Grauw, J., Cokelaere, S., Plomp, S., Groll, J.
, van Weeren, P. R., Gbureck, U.
, & Malda, J. (2020).
Long-Term in Vivo Performance of Low-Temperature 3D-Printed Bioceramics in an Equine Model.
ACS Biomaterials Science and Engineering,
6(3), 1681-1689.
https://doi.org/10.1021/acsbiomaterials.9b01819https://dspace.library.uu.nl/bitstream/handle/1874/408019/acsbiomaterials.9b01819.pdf?sequence=1Diloksumpan, P., de Ruijter, M., Castilho, M., Gbureck, U.
, Vermonden, T., van Weeren, P. R., Malda, J., & Levato, R. (2020).
Combining multi-scale 3D printing technologies to engineer reinforced hydrogel-ceramic interfaces.
Biofabrication,
12(2), Article 025014.
https://doi.org/10.1088/1758-5090/ab69d9https://dspace.library.uu.nl/bitstream/handle/1874/394410/Diloksumpan_2020_Biofabrication_12_025014.pdf?sequence=1 Cui, X., Soliman, B. G., Alcala-Orozco, C. R., Li, J., Vis, M. A. M., Santos, M., Wise, S. G.
, Levato, R., Malda, J., Woodfield, T. B. F., Rnjak-Kovacina, J., & Lim, K. S. (2020).
Rapid Photocrosslinking of Silk Hydrogels with High Cell Density and Enhanced Shape Fidelity.
Advanced healthcare materials,
9(4), Article e1901667.
https://doi.org/10.1002/adhm.201901667https://dspace.library.uu.nl/bitstream/handle/1874/394409/adhm.201901667.pdf?sequence=3Kristen, M., Ainsworth, M. J., Chirico, N., van der Ven, C. F. T., Doevendans, P. A., Sluijter, J. P. G.
, Malda, J., van Mil, A., & Castilho, M. (2020).
Fiber Scaffold Patterning for Mending Hearts: 3D Organization Bringing the Next Step.
Advanced healthcare materials,
9(1), e1900775.
https://doi.org/10.1002/adhm.201900775https://dspace.library.uu.nl/bitstream/handle/1874/389189/Kristen_et_al_2020_Advanced_Healthcare_Materials.pdf?sequence=1Mouser, V. H. M., Levato, R., Mensinga, A.
, Dhert, W. J. A., Gawlitta, D.
, & Malda, J. (2020).
Bio-ink development for three-dimensional bioprinting of hetero-cellular cartilage constructs.
Connective Tissue Research,
61(2), 137-151.
https://doi.org/10.1080/03008207.2018.1553960https://dspace.library.uu.nl/bitstream/handle/1874/394458/development.pdf?sequence=12019
Scholarly publications
Van Kampen, K. A., Scheuring, R. G., Terpstra, M. L.
, Levato, R., Groll, J.
, Malda, J., Mota, C., & Moroni, L. (2019).
Biofabrication: From additive manufacturing to bioprinting. In
Encyclopedia of Tissue Engineering and Regenerative Medicine (Vol. 1-3, pp. 41-55). Elsevier.
https://doi.org/10.1016/B978-0-12-801238-3.11118-3Tognato, R., Armiento, A. R., Bonfrate, V.
, Levato, R., Malda, J., Alini, M., Eglin, D., Giancane, G., & Serra, T. (2019).
A Stimuli-Responsive Nanocomposite for 3D Anisotropic Cell-Guidance and Magnetic Soft Robotics.
Advanced Functional Materials,
29(9).
https://doi.org/10.1002/adfm.201804647https://dspace.library.uu.nl/bitstream/handle/1874/391150/Tognato_et_al_2019_Advanced_Functional_Materials.pdf?sequence=1Bernal, P. N., Delrot, P., Loterie, D., Li, Y.
, Malda, J., Moser, C.
, & Levato, R. (2019).
Volumetric Bioprinting of Complex Living-Tissue Constructs within Seconds.
Advanced Materials,
31(42), Article 1904209.
https://doi.org/10.1002/adma.201904209https://dspace.library.uu.nl/bitstream/handle/1874/390216/Bernal_et_al_2019_Advanced_Materials.pdf?sequence=1Mancini, I. A. D., Rieppo, L., Pouran, B., Afara, I. O.
, Braganca, F. M. S., van Rijen, M. H. P.
, Kik, M., Weinans, H., Toyras, J.
, van Weeren, P. R., & Malda, J. (2019).
Effects of body mass on microstructural features of the osteochondral unit: A comparative analysis of 37 mammalian species.
Bone,
127, 664-673.
https://doi.org/10.1016/j.bone.2019.07.001https://dspace.library.uu.nl/bitstream/handle/1874/385052/Effects_of_body_mass.pdf?sequence=1 Klotz, B. J., Oosterhoff, L. A., Utomo, L., Lim, K. S., Vallmajo-Martin, Q.
, Clevers, H., Woodfield, T. B. F., Rosenberg, A. J. W. P.
, Malda, J., Ehrbar, M.
, Spee, B., & Gawlitta, D. (2019).
A Versatile Biosynthetic Hydrogel Platform for Engineering of Tissue Analogues.
Advanced healthcare materials,
2019(8), Article e1900979.
https://doi.org/10.1002/adhm.201900979https://dspace.library.uu.nl/bitstream/handle/1874/389131/Klotz_et_al_2019_Advanced_Healthcare_Materials.pdf?sequence=1 Sarin, J. K., Nykänen, O., Tiitu, V.
, Mancini, I. A. D., Brommer, H., Visser, J., Malda, J., van Weeren, P. R., Afara, I. O., & Töyräs, J. (2019).
Arthroscopic Determination of Cartilage Proteoglycan Content and Collagen Network Structure with Near-Infrared Spectroscopy.
Annals of Biomedical Engineering,
47(8), 1815-1826.
https://doi.org/10.1007/s10439-019-02280-7https://dspace.library.uu.nl/bitstream/handle/1874/382714/Sarin2019_Article_ArthroscopicDeterminationOfCar.pdf?sequence=1Visser, J., Melchels, F. P. W., Weinans, H., Kruyt, M. C.
, & Malda, J. (2019).
Mogelijkheden van 3D-printen in de geneeskunde: 5 jaar later.
Nederlands Tijdschrift voor Geneeskunde,
163, Article D3683.
https://www-ntvg-nl.proxy.library.uu.nl/artikelen/mogelijkheden-van-3d-printen-de-geneeskundehttps://dspace.library.uu.nl/bitstream/handle/1874/381726/NTvG_d3683.pdf?sequence=1 Castilho, M., Mouser, V., Chen, M.
, Malda, J., & Ito, K. (2019).
Bi-layered micro-fibre reinforced hydrogels for articular cartilage regeneration.
Acta Biomaterialia,
95, 297-306.
https://doi.org/10.1016/j.actbio.2019.06.030https://dspace.library.uu.nl/bitstream/handle/1874/432718/1-s2.0-S174270611930443X-main.pdf?sequence=1Nykänen, O., Sarin, J. K., Ketola, J. H., Leskinen, H.
, Te Moller, N. C. R., Tiitu, V.
, Mancini, I. A. D., Visser, J., Brommer, H., René van Weeren, P., Malda, J., Töyräs, J., & Nissi, M. J. (2019).
T2* and quantitative susceptibility mapping in an equine model of post-traumatic osteoarthritis: assessment of mechanical and structural properties of articular cartilage.
Osteoarthritis and Cartilage,
27(10), 1481-1490.
https://doi.org/10.1016/j.joca.2019.06.009https://research-portal.uu.nl/ws/files/237715074/1-s2.0-S1063458419311136-main.pdfPiluso, S., Li, Y., Abinzano, F., Levato, R.
, Moreira Teixeira, L., Karperien, M., Leijten, J.
, van Weeren, R., & Malda, J. (2019).
Mimicking the Articular Joint with In Vitro Models.
Trends in Biotechnology,
37(10), 1063-1077.
https://doi.org/10.1016/j.tibtech.2019.03.003https://dspace.library.uu.nl/bitstream/handle/1874/389444/piluso.pdf?sequence=1Lim, K. S.
, Klotz, B. J., Lindberg, G. C. J.
, Melchels, F. P. W., Hooper, G. J.
, Malda, J., Gawlitta, D., & Woodfield, T. B. F. (2019).
Visible Light Cross-Linking of Gelatin Hydrogels Offers an Enhanced Cell Microenvironment with Improved Light Penetration Depth.
Macromolecular Bioscience,
2019(19), Article 1900098.
https://doi.org/10.1002/mabi.201900098https://dspace.library.uu.nl/bitstream/handle/1874/381039/mabi.201900098.pdf?sequence=3Boere, J., van de Lest, C. H. A., de Grauw, J. C., Plomp, S. G. M., Libregts, S. F. W. M., Arkesteijn, G. J. A., Malda, J., Wauben, M. H. M., & van Weeren, P. R. (2019).
Extracellular vesicles in synovial fluid from juvenile horses: No age-related changes in the quantitative profile.
Veterinary Journal,
244, 91-93.
https://doi.org/10.1016/j.tvjl.2018.12.010https://dspace.library.uu.nl/bitstream/handle/1874/380517/1_s2.0_S1090023318307755_main.pdf?sequence=1 Jansen, K., Castilho, M., Aarts, S., Kaminski, M. M., Lienkamp, S. S., Pichler, R.
, Malda, J., Vermonden, T., Jansen, J., & Masereeuw, R. (2019).
Fabrication of Kidney Proximal Tubule Grafts Using Biofunctionalized Electrospun Polymer Scaffolds.
Macromolecular Bioscience,
19(2), Article e1800412.
https://doi.org/10.1002/mabi.201800412https://dspace.library.uu.nl/bitstream/handle/1874/389617/Jansen_et_al_2019_Macromolecular_Bioscience.pdf?sequence=1 Ruijter, M. D., Ribeiro, A., Dokter, I., Castilho, M.
, & Malda, J. (2019).
Simultaneous Micropatterning of Fibrous Meshes and Bioinks for the Fabrication of Living Tissue Constructs.
Advanced healthcare materials,
8(7), Article 1800418.
https://doi.org/10.1002/adhm.201800418https://dspace.library.uu.nl/bitstream/handle/1874/432160/Adv_Healthcare_Materials_-_2018_-_de_Ruijter_-_Simultaneous_Micropatterning_of_Fibrous_Meshes_and_Bioinks_for_the.pdf?sequence=12018
Scholarly publications
Van Mil, A., Castilho, M., Maher, M., Metz, C. H., Maas, R. G. C., Hochleitner, G., Groll, J., Ito, K., Malda, J., & Sluijter, J. P. G. (2018). Engineering myocardial tissue in vitro using stretchable microfiber scaffolds and human iPSC-derived cardiomyocytes. Cardiovascular Research, 114, S112-S112.
Sarin, J. K.
, te Moller, N., Brommer, H., van Weeren, R., Mancini, I., Malda, J., Afara, I. O., & Töyräs, J. (2018).
Spectroscopic Evaluation of Post-Traumatic Osteoarthritis in Shetland Ponies.
https://doi.org/10.1364/ots.2018.otu4d.5Chen, M. J., Kimpton, L. S., Whiteley, J. P., Castilho, M.
, Malda, J., Please, C. P., Waters, S. L., & Byrne, H. M. (2018).
Multiscale modelling and homogenisation of fibre-reinforced hydrogels for tissue engineering.
European Journal of Applied Mathematics,
31(1), 143-171.
https://doi.org/10.1017/S0956792518000657https://dspace.library.uu.nl/bitstream/handle/1874/392297/multiscale_modelling_and_homogenisation_of_fibrereinforced_hydrogels_for_tissue_engineering.pdf?sequence=1 de Graaf, P., van Velthoven, M., Ramadan, R., Klotz, B. J., Gawlitta, D., Castilho, M., Malda, J., Costa, P., & de Kort, L. M. O. (2018). Gel casting as an approach for tissue engineering of multilayered tubular structures: application for urethral reconstruction. Neurourology and Urodynamics, 37(S5), S208-S209.
Castilho, M., van Mil, A., Maher, M., Metz, C. H. G., Hochleitner, G., Groll, J., Doevendans, P. A., Ito, K., Sluijter, J. P. G.
, & Malda, J. (2018).
Melt Electrowriting Allows Tailored Microstructural and Mechanical Design of Scaffolds to Advance Functional Human Myocardial Tissue Formation.
Advanced Functional Materials,
28(40), Article 1803151.
https://doi.org/10.1002/adfm.201803151https://dspace.library.uu.nl/bitstream/handle/1874/381725/Castilho_et_al_2018_Advanced_Functional_Materials.pdf?sequence=1Güney, A., Gardiner, C., McCormack, A.
, Malda, J., & Grijpma, D. W. (2018).
Thermoplastic PCL-b-PEG-b-PCL and HDI Polyurethanes for Extrusion-Based 3D-Printing of Tough Hydrogels.
Bioengineering (Basel, Switzerland),
5(4), Article 99.
https://doi.org/10.3390/bioengineering5040099https://dspace.library.uu.nl/bitstream/handle/1874/376617/bioengineering_05_00099.pdf?sequence=1Groll, J., Burdick, J. A., Cho, D.-W., Derby, B., Gelinsky, M., Heilshorn, S. C., Jüngst, T.
, Malda, J., Mironov, V. A., Nakayama, K., Ovsianikov, A., Sun, W., Takeuchi, S., Yoo, J. J., & Woodfield, T. B. F. (2018).
A definition of bioinks and their distinction from biomaterial inks.
Biofabrication,
11(1), Article 013001.
https://doi.org/10.1088/1758-5090/aaec52https://dspace.library.uu.nl/bitstream/handle/1874/376084/groll.pdf?sequence=1Boere, J., Malda, J., van de Lest, C. H. A., van Weeren, P. R., & Wauben, M. H. M. (2018).
Extracellular Vesicles in Joint Disease and Therapy.
Frontiers in Immunology,
9, Article 2575.
https://doi.org/10.3389/fimmu.2018.02575https://dspace.library.uu.nl/bitstream/handle/1874/376018/Extracellular.pdf?sequence=1 Sarin, J. K.
, Te Moller, N. C. R., Mancini, I. A. D., Brommer, H., Visser, J., Malda, J., van Weeren, P. R., Afara, I. O., & Töyräs, J. (2018).
Arthroscopic near infrared spectroscopy enables simultaneous quantitative evaluation of articular cartilage and subchondral bone in vivo.
Scientific Reports,
8(1), Article 13409.
https://doi.org/10.1038/s41598-018-31670-5https://dspace.library.uu.nl/bitstream/handle/1874/374664/sarin.pdf?sequence=1Pouran, B., Arbabi, V., Bajpayee, A. G., van Tiel, J., Töyräs, J., Jurvelin, J. S.
, Malda, J., Zadpoor, A. A., & Weinans, H. (2018).
Multi-scale imaging techniques to investigate solute transport across articular cartilage.
Journal of Biomechanics,
78, 10-20.
https://doi.org/10.1016/j.jbiomech.2018.06.012de Almeida Monteiro Melo Ferraz, M., Henning, H. H. W., Ferreira da Costa, P.
, Malda, J., Le Gac, S., Bray, F.
, van Duursen, M. B. M., Brouwers, J. F., van de Lest, C. H. A., Bertijn, I., Kraneburg, L.
, Vos, P. L. A. M., Stout, T. A. E., & Gadella, B. M. (2018).
Potential Health and Environmental Risks of Three-Dimensional Engineered Polymers.
Environmental science & technology letters,
5(2), 80-85.
https://doi.org/10.1021/acs.estlett.7b00495https://dspace.library.uu.nl/bitstream/handle/1874/371939/ferraz.pdf?sequence=1 Sarin, J. K.
, te Moller, N., Brommer, H., van Weeren, R., Mancini, I.
, Malda, J., Afara, I. O., & To¨yräs, J. (2018).
Spectroscopic evaluation of post-traumatic osteoarthritis in Shetland ponies. In
Optical Tomography and Spectroscopy, OTS 2018 (Vol. Part F90-OTS 2018). OSA - The Optical Society.
https://doi.org/10.1364/OTS.2018.OTu4D.5Klotz, B. J., Lim, K. S., Chang, Y. X., Soliman, B. J., Pennings, I.
, Melchels, F. P., Melchels, F. P., Rosenberg, A. J. W. P.
, Malda, J., & Gawlittal, D. (2018).
Engineering of a complex bone tissue model with endothelialised channels and capillary-like networks.
European Cells and Materials,
35, 335-348.
https://doi.org/10.22203/eCM.v035a23https://dspace.library.uu.nl/bitstream/handle/1874/375301/v035a23.pdf?sequence=1 Lim, K. S., Levato, R., Ferreira da Costa, P., Castilho, M. D., Alcala-Orozco, C. R.
, van Dorenmalen, K. M. A., Melchels, F. P. W., Gawlitta, D., Hooper, G. J.
, Malda, J., & Woodfield, T. B. F. (2018).
Bio-resin for high resolution lithography-based biofabrication of complex cell-laden constructs.
Biofabrication,
10(3), Article 034101.
https://doi.org/10.1088/1758-5090/aac00cOtto, I. A., Levato, R., Webb, W. R., Khan, I. M., Breugem, C. C.
, & Malda, J. (2018).
Progenitor cells in auricular cartilage demonstrate cartilage-forming capacity in 3D hydrogel culture.
European Cells and Materials,
35, 132-150.
https://doi.org/10.22203/eCM.v035a10https://dspace.library.uu.nl/bitstream/handle/1874/374968/otto.pdf?sequence=1Castilho, M., Hochleitner, G., Wilson, W., van Rietbergen, B., Dalton, P. D., Groll, J.
, Malda, J., & Ito, K. (2018).
Mechanical behavior of a soft hydrogel reinforced with three-dimensional printed microfibre scaffolds.
Scientific Reports,
8(1), Article 1245.
https://doi.org/10.1038/s41598-018-19502-yhttps://dspace.library.uu.nl/bitstream/handle/1874/374950/castilho.pdf?sequence=1Pouran, B., Moshtagh, P. R., Arbabi, V., Snabel, J., Stoop, R., Ruberti, J.
, Malda, J., Zadpoor, A. A., & Weinans, H. (2018).
Non-enzymatic cross-linking of collagen type II fibrils is tuned via osmolality switch.
Journal of Orthopaedic Research,
36(7), 1929-1936.
https://doi.org/10.1002/jor.23857https://dspace.library.uu.nl/bitstream/handle/1874/374949/pouran.pdf?sequence=1Ruijter, M. D., Hrynevich, A., Haigh, J. N., Hochleitner, G., Castilho, M., Groll, J.
, Malda, J., & Dalton, P. D. (2018).
Out-of-Plane 3D-Printed Microfibers Improve the Shear Properties of Hydrogel Composites.
Small,
14(8), 14.
https://doi.org/10.1002/smll.201702773https://dspace.library.uu.nl/bitstream/handle/1874/363920/Microfibers.pdf?sequence=1Mouser, V. H. M., Dautzenberg, N. M. M., Levato, R., van Rijen, M. H. P.
, Dhert, W. J. A., Malda, J., & Gawlitta, D. (2018).
Ex vivo model unravelling cell distribution effect in hydrogels for cartilage repair.
Altex,
35(1), 65-76.
https://doi.org/10.14573/altex.1704171https://dspace.library.uu.nl/bitstream/handle/1874/361623/mouser.pdf?sequence=1Moroni, L., Boland, T., Burdick, J. A., De Maria, C., Derby, B., Forgacs, G., Groll, J., Li, Q.
, Malda, J., Mironov, V. A., Mota, C., Nakamura, M., Shu, W., Takeuchi, S., Woodfield, T. B. F., Xu, T., Yoo, J. J., & Vozzi, G. (2018).
Biofabrication: A Guide to Technology and Terminology.
Trends in Biotechnology,
36(4), 384-402.
https://doi.org/10.1016/j.tibtech.2017.10.015https://dspace.library.uu.nl/bitstream/handle/1874/377392/Biofabrication.pdf?sequence=1Other output
Sarin, J. K.
, te Moller, N. C. R., Brommer, H., van Weeren, P. R., Mancini, I. A. D., Malda, J., Afara, I. O., & Töyräs, J. (2018).
Spectroscopic Evaluation of Post-Traumatic Osteoarthritis in Shetland Ponies. Abstract from Optical Tomography and Spectroscopy, Florida, United States.
https://doi.org/10.1364/OTS.2018.OTu4D.52017
Scholarly publications
Webb, W. R., Levato, R., van Weeren, P. R., Malda, J., & Khan, I. M. (2017). The potential use of microcarriers as a vehicle to deliver and differentiate chondroprogenitors. International Journal of Experimental Pathology, 98(1), A20-A21.
Woodfield, T., Lim, K., Morouço, P.
, Levato, R., Malda, J., & Melchels, F. (2017).
5.14 Biofabrication in tissue engineering. In P. Ducheyne (Ed.),
Comprehensive Biomaterials II (pp. 236-266). Elsevier.
https://doi.org/10.1016/B978-0-12-803581-8.10221-8Ferreira da Costa, P., Albers, H. J., Linssen, J. E. A., Middelkamp, H. H. T., van der Hout, L., Passier, R., van den Berg, A.
, Malda, J., & van der Meer, A. D. (2017).
Mimicking arterial thrombosis in a 3D-printed microfluidic in vitro vascular model based on computed tomography angiography data.
Lab on a Chip - Miniaturisation for Chemistry and Biology,
17(16), 2785-2792.
https://doi.org/10.1039/c7lc00202ehttps://dspace.library.uu.nl/bitstream/handle/1874/360913/Mimicking.pdf?sequence=1Levato, R., Webb, W. R., Otto, I. A., Mensinga, A., Zhang, Y., van Rijen, M.
, van Weeren, R., Khan, I. M.
, & Malda, J. (2017).
The bio in the ink: cartilage regeneration with bioprintable hydrogels and articular cartilage-derived progenitor cells.
Acta Biomaterialia,
61, 41-53.
https://doi.org/10.1016/j.actbio.2017.08.005https://dspace.library.uu.nl/bitstream/handle/1874/360437/Bio.pdf?sequence=1Stichler, S., Böck, T., Paxton, N. C., Bertlein, S., Levato, R., Schill, V., Smolan, W.
, Malda, J., Tessmar, J., Blunk, T., & Groll, J. (2017).
Double printing of hyaluronic acid / poly(glycidol) hybrid hydrogels with poly(ε-caprolactone) for MSC chondrogenesis.
Biofabrication,
9(4), Article 044108.
https://doi.org/10.1088/1758-5090/aa8cb7https://dspace.library.uu.nl/bitstream/handle/1874/361622/Stichler_2017_Biofabrication_9_044108.pdf?sequence=1Mouser, V. H. M., Levato, R., Bonassar, L. J., D'Lima, D. D., Grande, D. A., Klein, T. J., Saris, D. B. F., Zenobi-Wong, M., Gawlitta, D.
, & Malda, J. (2017).
Three-Dimensional Bioprinting and Its Potential in the Field of Articular Cartilage Regeneration.
Cartilage,
8(4), 327-340.
https://doi.org/10.1177/1947603516665445https://dspace.library.uu.nl/bitstream/handle/1874/360912/threedimensional.pdf?sequence=1Ribeiro, A.
, Blokzijl, M. M., Levato, R., Visser, C. W., Castilho, M.
, Hennink, W. E., Vermonden, T., & Malda, J. (2017).
Assessing bioink shape fidelity to aid material development in 3D bioprinting.
Biofabrication,
10, Article 014102.
https://doi.org/10.1088/1758-5090/aa90e2https://dspace.library.uu.nl/bitstream/handle/1874/361621/ribeiro.pdf?sequence=1Mancini, I. A. D., Vindas Bolaños, R. A.
, Brommer, H., Castilho, M., Ribeiro, A.
, van Loon, J. P. A. M., Mensinga, A., van Rijen, M. H. P.
, Malda, J., & van Weeren, R. (2017).
Fixation of Hydrogel Constructs for Cartilage Repair in the Equine Model: A Challenging Issue.
Tissue engineering. Part C, Methods,
23(11), 804-814.
https://doi.org/10.1089/ten.TEC.2017.0200https://dspace.library.uu.nl/bitstream/handle/1874/360436/ten.tec.2017.0200.pdf?sequence=1 Castilho, M., Feyen, D., Flandes-Iparraguirre, M., Hochleitner, G., Groll, J., Doevendans, P. A. F.
, Vermonden, T., Ito, K., Sluijter, J. P. G.
, & Malda, J. (2017).
Melt Electrospinning Writing of Poly-Hydroxymethylglycolide-co-ε-Caprolactone-Based Scaffolds for Cardiac Tissue Engineering.
Advanced healthcare materials,
6(18), Article 1700311.
https://doi.org/10.1002/adhm.201700311https://dspace.library.uu.nl/bitstream/handle/1874/356029/Melt.pdf?sequence=1Groen, W. M.
, Diloksumpan, P., van Weeren, P. R., Levato, R.
, & Malda, J. (2017).
From intricate to integrated: Biofabrication of articulating joints.
Journal of Orthopaedic Research,
35(10), 2089–2097.
https://doi.org/10.1002/jor.23602https://dspace.library.uu.nl/bitstream/handle/1874/360418/Groen_et_al_2017_Journal_of_Orthopaedic_Research.pdf?sequence=1Mouser, V. H. M.
, Abbadessa, A., Levato, R.
, Hennink, W., Vermonden, T., Gawlitta, D.
, & Malda, J. (2017).
Development of a thermosensitive HAMA-containing bio-ink for the fabrication of composite cartilage repair constructs.
Biofabrication,
9(1), Article 015026.
https://doi.org/10.1088/1758-5090/aa6265https://dspace.library.uu.nl/bitstream/handle/1874/360808/mouser.pdf?sequence=1Schneeberger, K., Spee, B., Costa, P., Sachs, N.
, Clevers, H., & Malda, J. (2017).
Converging biofabrication and organoid technologies: the next frontier in hepatic and intestinal tissue engineering? Biofabrication,
9, Article 013001.
https://doi.org/10.1088/1758-5090/aa6121https://dspace.library.uu.nl/bitstream/handle/1874/360389/Schneeberger_2017_Biofabrication_9_013001.pdf?sequence=1 de Almeida Monteiro Melo Ferraz, M., Henning, H. H. W., Ferreira da Costa, P.
, Malda, J., Melchels, F. P. W.
, Wubbolts, R. W., Stout, T. A. E., Vos, P. L. A. M., & Gadella, B. M. (2017).
Improved bovine embryo production in an oviduct-on-a-chip system: prevention of poly-spermic fertilization and parthenogenic activation.
Lab on a Chip - Miniaturisation for Chemistry and Biology,
17(5), 905-916.
https://doi.org/10.1039/c6lc01566bhttps://dspace.library.uu.nl/bitstream/handle/1874/360794/c6lc01566b.pdf?sequence=1 Vindas Bolaños, R. A.
, Cokelaere, S. M., Estrada McDermott, J. M., Benders, K. E. M., Gbureck, U.
, Plomp, S. G. M., Weinans, H., Groll, J.
, van Weeren, P. R., & Malda, J. (2017).
The use of a cartilage decellularized matrix scaffold for the repair of osteochondral defects: the importance of long-term studies in a large animal model.
Osteoarthritis and Cartilage,
25(3), 413–420.
https://doi.org/10.1016/j.joca.2016.08.005https://dspace.library.uu.nl/bitstream/handle/1874/346772/cartilage.pdf?sequence=1Zhao, X., Hwang, N. S., Bichara, D. A., Saris, D. B.
, Malda, J., Vacanti, J. P., Pomerantseva, I., Sundback, C. A., Langer, R., Anderson, D. G., & Randolph, M. A. (2017).
Chondrogenesis by bone marrow-derived mesenchymal stem cells grown in chondrocyte-conditioned medium for auricular reconstruction.
Journal of Tissue Engineering and Regenerative Medicine,
11(10), 2763-2773.
https://doi.org/10.1002/term.2171https://research-portal.uu.nl/ws/files/251705151/J_Tissue_Eng_Regen_Med_-_2016_-_Zhao_-_Chondrogenesis_by_bone_marrow_derived_mesenchymal_stem_cells_grown_in.pdf2016
Scholarly publications
Mok, S.-W., Nizak, R., Fu, S.-C., Ho, K.-W. K., Qin, L., Saris, D. B. F., Chan, K.-M.
, & Malda, J. (2016).
From the printer: Potential of three-dimensional printing for orthopaedic applications.
Journal of Orthopaedic Translation,
6, 42-49.
https://doi.org/10.1016/j.jot.2016.04.003Jessop, Z. M., Javed, M., Otto, I. A., Combellack, E. J., Morgan, S., Breugem, C. C., Archer, C. W., Khan, I. M., Lineaweaver, W. C., Kon, M.
, Malda, J., & Whitaker, I. S. (2016).
Combining regenerative medicine strategies to provide durable reconstructive options: auricular cartilage tissue engineering.
Stem cell research & therapy,
7, Article 19.
https://doi.org/10.1186/s13287-015-0273-0https://dspace.library.uu.nl/bitstream/handle/1874/352055/Combining.pdf?sequence=1Otto, I. A., van Doremalen, R. F. M.
, Melchels, F. P. W., Kolodzynski, M. N., Pouran, B.
, Malda, J., Kon, M., & Breugem, C. C. (2016).
Accurate Measurements of the Skin Surface Area of the Healthy Auricle and Skin Deficiency in Microtia Patients.
Plastic and reconstructive surgery. Global open,
4(12), Article e1146.
https://doi.org/10.1097/GOX.0000000000001146https://dspace.library.uu.nl/bitstream/handle/1874/348935/accurate.pdf?sequence=1Boere, J., van de Lest, C. H. A., Libregts, S. F. W. M., Arkesteijn, G. J. A.
, Geerts, W. J. C., Nolte-'t Hoen, E. N. M., Malda, J., van Weeren, P. R., & Wauben, M. H. M. (2016).
Synovial fluid pretreatment with hyaluronidase facilitates isolation of CD44+ extracellular vesicles.
Journal of Extracellular Vesicles,
5(1), Article 31751.
https://doi.org/10.3402/jev.v5.31803https://dspace.library.uu.nl/bitstream/handle/1874/346760/Synovial.pdf?sequence=1 Mouser, V. H. M.
, Melchels, F. P. W., Visser, J., Dhert, W. J. A., Gawlitta, D.
, & Malda, J. (2016).
Yield stress determines bioprintability of hydrogels based on gelatin-methacryloyl and gellan gum for cartilage bioprinting.
Biofabrication,
8(3), Article 035003.
https://doi.org/10.1088/1758-5090/8/3/035003https://dspace.library.uu.nl/bitstream/handle/1874/341059/Yield.pdf?sequence=1Melchels, F. P. W., Blokzijl, M. M., Levato, R., Peiffer, Q. C., Ruijter, M. D.
, Hennink, W. E., Vermonden, T., & Malda, J. (2016).
Hydrogel-based reinforcement of 3D bioprinted constructs.
Biofabrication,
8(3), Article 035004.
https://doi.org/10.1088/1758-5090/8/3/035004https://dspace.library.uu.nl/bitstream/handle/1874/346755/Hydrogel.pdf?sequence=1 Carter, S.-S. D., Vaquette, C., Ivanovski, S., Hutmacher, D. W.
, & Malda, J. (2016).
Additive Biomanufacturing: An Advanced Approach for Periodontal Tissue Regeneration.
Annals of Biomedical Engineering,
45(1), 12–22.
https://doi.org/10.1007/s10439-016-1687-2https://dspace.library.uu.nl/bitstream/handle/1874/346754/Additive.pdf?sequence=1Zhao, X., Papadopoulos, A., Ibusuki, S., Bichara, D. A., Saris, D. B.
, Malda, J., Anseth, K. S., Gill, T. J., & Randolph, M. A. (2016).
Articular cartilage generation applying PEG-LA-DM/PEGDM copolymer hydrogels.
BMC Musculoskeletal Disorders [E],
17(1), 1-10. Article 245.
https://doi.org/10.1186/s12891-016-1100-1https://dspace.library.uu.nl/bitstream/handle/1874/345458/Articular.pdf?sequence=1Abbadessa, A., Blokzijl, M. M., Mouser, V. H. M., Marica, P.
, Malda, J., Hennink, W. E., & Vermonden, T. (2016).
A thermo-responsive and photo-polymerizable chondroitin sulfate-based hydrogel for 3D printing applications.
Carbohydr Polym,
149, 163-174.
https://doi.org/10.1016/j.carbpol.2016.04.080https://dspace.library.uu.nl/bitstream/handle/1874/345949/thermo_responsive.pdf?sequence=1 Abbadessa, A., Mouser, V. H. M.
, Blokzijl, M. M., Gawlitta, D.
, Dhert, W. J. A., Hennink, W. E., Malda, J., & Vermonden, T. (2016).
A Synthetic Thermosensitive Hydrogel for Cartilage Bioprinting and Its Biofunctionalization with Polysaccharides.
Biomacromolecules,
17(6), 2137-2147.
https://doi.org/10.1021/acs.biomac.6b00366https://dspace.library.uu.nl/bitstream/handle/1874/345451/Synthetic.pdf?sequence=1 Klotz, B. J., Gawlitta, D., Rosenberg, A. J. W. P.
, Malda, J., & Melchels, F. P. W. (2016).
Gelatin-Methacryloyl Hydrogels: Towards Biofabrication-Based Tissue Repair.
Trends in Biotechnology,
34(5), 394-407.
https://doi.org/10.1016/j.tibtech.2016.01.002https://dspace.library.uu.nl/bitstream/handle/1874/345912/Gelatin_Methacryloyl.pdf?sequence=1 Groll, J., Boland, T., Blunk, T., Burdick, J. A., Cho, D.-W., Dalton, P. D., Derby, B., Forgacs, G., Li, Q., Mironov, V. A., Moroni, L., Nakamura, M., Shu, W., Takeuchi, S., Vozzi, G., Woodfield, T. B. F., Xu, T., Yoo, J. J.
, & Malda, J. (2016).
Biofabrication: reappraising the definition of an evolving field.
Biofabrication,
8(1), 1-5. Article 013001.
https://doi.org/10.1088/1758-5090/8/1/013001https://dspace.library.uu.nl/bitstream/handle/1874/345426/Biofabrication.pdf?sequence=1Malda, J., Boere, J., van de Lest, C. H. A., van Weeren, P. R., & Wauben, M. H. M. (2016).
Extracellular vesicles - new tool for joint repair and regeneration.
Nature reviews. Rheumatology,
12, 243-249.
https://doi.org/10.1038/nrrheum.2015.170https://dspace.library.uu.nl/bitstream/handle/1874/345882/Extracellular.pdf?sequence=1 Other output
Serra Braganca, F. M., Mancini, I.
, Brommer, H., Malda, J., Visser, J., & René van Weeren, P. (2016).
COMPENSATORY MECHANISM OF GAIT ADAPTATION TO BILATERAL STIFLE JOINT INJURIES IN SHETLAND PONIES AT TROT.
https://doi.org/10.1111/evj.27_12595 2015
Scholarly publications
Chan, K.-M., Rolf, C. G., Qin, L., Felländer-Tsai, L., Castelein, R. M., Saris, D. B. F.
, Malda, J., Richards, G., Goodman, S. B., Tuan, R. S., Maloney, W., Lidgren, L., Hopkins, C., Fu, S.-C., Li, G., Ding, M., Tang, T., Zhang, X., Wei, L., ... Ouyang, H. (2015).
Musculoskeletal regeneration research network: A global initiative.
Journal of Orthopaedic Translation,
3(4), 160-165.
https://doi.org/10.1016/j.jot.2015.08.007Visser, J., Melchels, F. P. W., Mancini, I. A. D., Brommer, H., Jeon, J. E., Dalton, P. D., Dhert, W. J. A., Saris, D. B. F., Hutmacher, D. W., van Weeren, P. R., & Malda, J. (2015). Reinforced gelatin hydrogels for cartilage repair; from in vitro testing to implantation in the equine stifle join. In Reinforced gelatin hydrogels for cartilage repair; from in vitro testing to implantation in the equine stifle join
Visser, J., Melchers, F., Mancini, I. A. D., Brommer, H., Jeon, J. E., Dalton, P., Dhert, W. J. A., Saris, D. B. F., Hutmacher, D. W., van Weeren, P. R., & Malda, J. (2015). Reinforced gelatin hydrogels for cartilage repair: from in vitro testing to implantation in the equine knee joint. In Reinforced gelatin hydrogels for cartilage repair: from in vitro testing to implantation in the equine knee joint
Otto, I. A., Melchels, F. P. W., Zhao, X., Randolph, M. A., Kon, M., Breugem, C. C.
, & Malda, J. (2015).
Auricular reconstruction using biofabrication-based tissue engineering strategies.
Biofabrication,
7(3), 032001.
https://doi.org/10.1088/1758-5090/7/3/032001Visser, J., Gawlitta, D., Benders, K. E. M., Toma, S. M. H., Pouran, B.
, van Weeren, P. R., Dhert, W. J. A., & Malda, J. (2015).
Endochondral bone formation in gelatin methacrylamide hydrogel with embedded cartilage-derived matrix particles.
Biomaterials,
37, 174-182.
https://doi.org/10.1016/j.biomaterials.2014.10.020 Boere, K. W. M., Blokzijl, M. M., Visser, J., Linssen, J. E. A.
, Malda, J., Hennink, W. E., & Vermonden, T. (2015).
Biofabrication of reinforced 3D-scaffolds using two-component hydrogels.
Journal of Materials Chemistry A,
3(46), 9067-9078.
https://doi.org/10.1039/c5tb01645bhttps://dspace.library.uu.nl/bitstream/handle/1874/428104/c5tb01645b.pdf?sequence=1 Visser, J., Levett, P. A.
, te Moller, N. C. R., Besems, J.
, Boere, K. W. M., van Rijen, M. H. P.
, de Grauw, J. C., Dhert, W. J. A., van Weeren, P. R., & Malda, J. (2015).
Crosslinkable Hydrogels Derived from Cartilage, Meniscus, and Tendon Tissue.
Tissue Engineering. Part A,
21(7-8), 1195-1206.
https://doi.org/10.1089/ten.tea.2014.0362 Visser, J., Melchels, F. P. W., Jeon, J. E., van Bussel, E. M., Kimpton, L. S., Byrne, H. M.
, Dhert, W. J. A., Dalton, P. D., Hutmacher, D. W.
, & Malda, J. (2015).
Reinforcement of hydrogels using three-dimensionally printed microfibres.
Nature Communications [E],
6, Article 6933.
https://doi.org/10.1038/ncomms7933https://dspace.library.uu.nl/bitstream/handle/1874/327177/ncomms7933.pdf?sequence=1Schuurman, W., Klein, T. J.
, Dhert, W. J. A., van Weeren, P. R., Hutmacher, D. W.
, & Malda, J. (2015).
Cartilage regeneration using zonal chondrocyte subpopulations: a promising approach or an overcomplicated strategy? Journal of Tissue Engineering and Regenerative Medicine,
9(6), 669-678.
https://doi.org/10.1002/term.1638 Gawlitta, D., Benders, K. E. M., Visser, J., van der Sar, A. S., Kempen, D. H. R.
, Theyse, L. F. H., Malda, J., & Dhert, W. J. A. (2015).
Decellularized Cartilage-Derived Matrix as Substrate for Endochondral Bone Regeneration.
Tissue Engineering. Part A,
21(3-4), 694-703.
https://doi.org/10.1089/ten.TEA.2014.0117https://dspace.library.uu.nl/bitstream/handle/1874/314325/ten.tea.2014.pdf?sequence=1Other output
Boere, J., van de Lest, C. H. A., de Grauw, J. C., Libregts, S. F. W. M., Arkesteijn, G., Bergman, J., Geerts, W. J., Malda, J., Wauben, M. H. M., & René van Weeren, P. (2015). Quantitative and qualitative analysis of synovial fluid extracellular vesicles in an equine model for acute synovitis. Abstract from Veterinary Science Day, Bunnik, Netherlands.
Boere, J., van de Lest, C. H. A., de Grauw, J. C., Malda, J., van Weeren, P. R., & Wauben, M. H. M. (2015). High-resolution flow cytometric analysis of synovial fluid derived extracellular vesicle populations during joint inflammation. Abstract from ISEV annual meeting 2015, Washington, DC, United States.
2014
Scholarly publications
Benders, K. E. M., Boot, W.
, van Weeren, R., Gawlitta, D., Bergman, E., Saris, D. B. F.
, Dhert, W., & Malda, J. (2014).
Multipotent stromal cells outperform chondrocytes on cartilage-derived matrix scaffolds.
Cartilage,
5(4), 221-230.
https://doi.org/10.1177/1947603514535245Levato, R.
, Visser, J., Planell, J. A., Engel, E.
, Malda, J., & Mateos-Timoneda, M. A. (2014).
Biofabrication of tissue constructs by 3D bioprinting of cell-laden microcarriers. Biofabrication,
6(3), Article 035020.
https://doi.org/10.1088/1758-5082/6/3/035020Kock, L. M.
, Malda, J., Dhert, W. J. A., Ito, K., & Gawlitta, D. (2014).
Flow-perfusion interferes with chondrogenic and hypertrophic matrix production by mesenchymal stem cells.
Journal of Biomechanics,
47(9), 2122-2129.
https://doi.org/10.1016/j.jbiomech.2013.11.006https://dspace.library.uu.nl/bitstream/handle/1874/314332/flow.pdf?sequence=1Levett, P. A.
, Melchels, F. P. W., Schrobback, K., Hutmacher, D. W.
, Malda, J., & Klein, T. J. (2014).
A biomimetic extracellular matrix for cartilage tissue engineering centered on photocurable gelatin, hyaluronic acid and chondroitin sulfate. Acta Biomaterialia,
10(1), 214-223.
https://doi.org/10.1016/j.actbio.2013.10.005Levett, P. A.
, Melchels, F. P. W., Schrobback, K., Hutmacher, D. W.
, Malda, J., & Klein, T. J. (2014).
Chondrocyte redifferentiation and construct mechanical property development in single-component photocrosslinkable hydrogels. Journal of Biomedical Materials Research. Part A.,
102(8), 2544-2553.
https://doi.org/10.1002/jbm.a.34924Boere, K. W. M., Visser, J., Seyednejad, H., Rahimian, S., Gawlitta, D.
, Van Steenbergen, M. J., Dhert, W. J. A., Hennink, W. E., Vermonden, T., & Malda, J. (2014).
Covalent attachment of a three-dimensionally printed thermoplast to a gelatin hydrogel for mechanically enhanced cartilage constructs.
Acta Biomaterialia,
10(6), 2602-2611.
https://doi.org/10.1016/j.actbio.2014.02.041 Other output
Boere, J., de Grauw, J., van de Lest, C., Malda, J., Wauben, M., & van Weeren, R. (2014). Increased concentration of extracellular vesicles in the synovial fluid during synovitis LPS-induced inflammation in the joint. Abstract from Dutch Society for Matrix Biology (NVMB) Symposium, Amersfoort, Netherlands.
Boere, J., van der Vrande, S., van de Lest, C., Malda, J., & van Weeren, R. (2014). Zonal organization in prenatal cartilage: the basis for cartilage tissue engineering?. Abstract from Dutch Society for Tissue Engineering (NBTE) Annual Meeting, Lunteren, Netherlands.
Boere, J., van de Lest, C., Nolte - t Hoen, E., Libregts, S., Wubbolts, R., de Grauw, J., Malda, J., Wauben, M., & van Weeren, R. (2014). Cartilage homeostasis might be regulated by extracellular vesicles facilitating intercellular communication between joint cells (3). Abstract from NIRM consortium meeting, Rotterdam, Netherlands.
Boere, J., van de Lest, C., Nolte - t Hoen, E., Libregts, S., Wubbolts, R., de Grauw, J., Malda, J., Wauben, M., & van Weeren, R. (2014). Cartilage homeostasis might be regulated by extracellular vesicles facilitating intercellular communication between joint cells (2). Abstract from FEBS workshop: Lipids as Molecular Switches, Island of Spetses, Greece.
Boere, J., van de Lest, C., Nolte - t Hoen, E., Libregts, S., Wubbolts, R., de Grauw, J., Malda, J., Wauben, M., & van Weeren, R. (2014). Cartilage homeostasis might be regulated by extracellular vesicles facilitating intercellular communication between joint cells. Abstract from 1st Matrix Biology Europe (MBE) conference (XXIVth FECTS meeting), Rotterdam, Netherlands.
Boere, J., van de Lest, C., Nolte - t Hoen, E., Libregts, S., Wubbolts, R., de Grauw, J., Malda, J., Wauben, M., & van Weeren, R. (2014). Extracellular vesicles isolated from equine synovial fluid bind to and are internalized by chondrocytes and synoviocytes in vitro. Abstract from International Society for Extracellular Vesicles (ISEV) Annual Meeting, Rotterdam, Netherlands.
2013
Scholarly publications
McCarthy, H. S.
, Malda, J., Richardson, J. B., & Roberts, S. (2013).
Increased Production of Clusterin in Biopsies of Repair Tissue following Autologous Chondrocyte Implantation.
Cartilage,
4(3), 227-238.
https://doi.org/10.1177/1947603513477652Schuurman, W., Harimulyo, E. B., Gawlitta, D., Woodfield, T. B. F.
, Dhert, W. J. A., van Weeren, P. R., & Malda, J. (2013).
Three-dimensional assembly of tissue-engineered cartilage constructs results in cartilaginous tissue formation without retainment of zonal characteristics.
Journal of Tissue Engineering and Regenerative Medicine,
10(4), 315-324.
https://doi.org/10.1002/term.1726 Malda, J., de Grauw, J. C., Benders, K. E. M.
, Kik, M. J. L., van de Lest, C. H. A., Creemers, L. B.
, Dhert, W. J. A., & van Weeren, P. R. (2013).
Of mice, men and elephants: the relation between articular cartilage thickness and body mass. PLoS One,
8(2), e57683.
http://www.ncbi.nlm.nih.gov/pubmed/23437402 Benders, K. E. M.
, van Weeren, P. R., Badylak, S. F., Saris, D. B. F.
, Dhert, W. J. A., & Malda, J. (2013).
Extracellular matrix scaffolds for cartilage and bone regeneration. Trends in Biotechnology,
31(3), 169-176.
https://doi.org/10.1016/j.tibtech.2012.12.004Malda, J., Visser, J., Melchels, F. P., Juengst, T.
, Hennink, W. E., Dhert, W. J. A., Groll, J., & Hutmacher, D. W. (2013).
25th Anniversary Article: Engineering Hydrogels for Biofabrication.
Advanced Materials,
25(36), 5011-5028.
https://doi.org/10.1002/adma.201302042 Schuurman, W., Levett, P. A., Pot, M. W.
, van Weeren, P. R., Dhert, W. J. A., Hutmacher, D. W.
, Melchels, F. P. W., Klein, T. J.
, & Malda, J. (2013).
Gelatin-methacrylamide hydrogels as potential biomaterials for fabrication of tissue-engineered cartilage constructs.
Macromolecular Bioscience,
13(5), 551-561.
https://doi.org/10.1002/mabi.201200471 Visser, J., Peters, B., Burger, T. J., Boomstra, J.
, Dhert, W. J. A., Melchels, F. P. W., & Malda, J. (2013).
Biofabrication of multi-material anatomically shaped tissue constructs.
Biofabrication,
5(3), 035007.
https://doi.org/10.1088/1758-5082/5/3/035007 Professional publications
Visser, J.
, Melchels, F. P. W., Dhert, W. J. A., & Malda, J. (2013).
[Tissue printing; the potential application of 3D printing in medicine]. Nederlands Tijdschrift voor Geneeskunde,
157(52), A7043.
http://www.ncbi.nlm.nih.gov/pubmed/24382049Other output
Malda, J. (2013). Engineering of hydrogel-based bioinks for the fabrication of cell-laden 3D constructs. Human Gene Therapy, 24(12), A27-A27.
Boere, J., van de Lest, C., Malda, J., & van Weeren, R. (2013). Isolation and anaylsis of nano-sized vesicles from equine synovial fluid (2). Abstract from NIRM consortium meeting, Utrecht, Netherlands.
Boere, J., van de Lest, C. H. A., Malda, J., & van Weeren, P. R. (2013). Isolation and analysis of nano-sized particles from equine synovial fluid. Abstract from Dutch Society for Matrix Biology (NVMB) Annual Meeting, Netherlands.
Visser, J., Levett, P. A., Te Moller, N. C. R., Besems, J., de Grauw, J. C., van Weeren, P. R., Dhert, W. J. A., & Malda, J. (2013). Arthroscopic optical coherence tomography provides detailed information on articular cartilage lesions in horses.. Abstract from Ann. Meet. Dutch Soc. Matriox Biol., Lunteren, May 2013..
Boere, J., van de Lest, C. H. A., de Grauw, J. C., Wauben, M. H. M., Malda, J., & van Weeren, P. R. (2013). Intercellular communication in the equine joint: lipidome analysis of cell-derived vesicles. Abstract from Dutch Society for Biomaterials and Tissue Engineering (NBTE) Annual Meeting, Lunteren, Netherlands.
Boere, J., van de Lest, C. H. A., de Grauw, J. C., Wauben, M. H. M., Malda, J., & van Weeren, P. R. (2013). Lipidome analysis of cell-derived vesicles in the equine joint. Abstract from Veterinary Science Day November 14th.
2012
Scholarly publications
Schrobback, K., Klein, T. J., Crawford, R., Upton, Z.
, Malda, J., & Leavesley, D. I. (2012).
Effects of oxygen and culture system on in vitro propagation and redifferentiation of osteoarthritic human articular chondrocytes.
Cell and Tissue Research,
347(3), 649-63.
https://doi.org/10.1007/s00441-011-1193-7Schrobback, K.
, Malda, J., Crawford, R. W., Upton, Z., Leavesley, D. I., & Klein, T. J. (2012).
Effects of oxygen on zonal marker expression in human articular chondrocytes.
Tissue Engineering. Part A,
18(9-10), 920-33.
https://doi.org/10.1089/ten.TEA.2011.0088Fedorovich, N. E.
, Schuurman, W., Wijnberg, H. M., Prins, H.
, van Weeren, P. R., Malda, J., Alblas, J.
, & Dhert, W. J. A. (2012).
Biofabrication of osteochondral tissue equivalents by printing topologically defined, cell-laden hydrogel scaffolds. Tissue engineering. Part C, Methods,
18(1), 33-44.
https://doi.org/10.1089/ten.TEC.2011.0060Malda, J., Benders, K. E. M., Klein, T. J.
, de Grauw, J. C., Kik, M. J. L., Hutmacher, D. W., Saris, D. B. F.
, van Weeren, P. R., & Dhert, W. J. A. (2012).
Comparative study of depth-dependent characteristics of equine and human osteochondral tissue from the medial and lateral femoral condyles.
Osteoarthritis and Cartilage,
20(10), 1147-1151.
https://doi.org/10.1016/j.joca.2012.06.005 Other output
Boere, J., van de Lest, C., Redout, E., de Grauw, J., Malda, J., & van Weeren, R. (2012). Similar effects of interleukin-1beta on cartilage explant cultures in media supplemented with adult serum, adult synovial fluid or immature serum. Abstract from 21st Ann. Meet. Dutch Society for Biomaterials and Tissue Engineering (NBTE) (Lunteren The Netherlands).
2011
Scholarly publications
Schrobback, K., Klein, T. J., Schuetz, M., Upton, Z., Leavesley, D. I.
, & Malda, J. (2011).
Adult human articular chondrocytes in a microcarrier-based culture system: expansion and redifferentiation.
Journal of Orthopaedic Research,
29(4), 539-46.
https://doi.org/10.1002/jor.21264Rouwkema, J., Gibbs, S., Lutolf, M. P., Martin, I., Vunjak-Novakovic, G.
, & Malda, J. (2011).
In vitro platforms for tissue engineering: implications for basic research and clinical translation.
Journal of Tissue Engineering and Regenerative Medicine,
5(8), e164-7.
https://doi.org/10.1002/term.414Censi, R., Schuurman, W., Malda, J., Di Dato, G., Burgisser, P., Dhert, W. J. A., van Nostrum, C. F., Vermonden, T., & Hennink, W. E. (2011). A Printable Photopolymerizable Thermosensitive p(HPMAm-lactate)-PEG Hydrogel for Tissue Engineering. Advanced Functional Materials, 10, 1833-1842.
Schuurman, W., Khristov, V., Pot, M. W.
, van Weeren, P. R., Dhert, W. J. A., & Malda, J. (2011).
Bioprinting of hybrid tissue constructs with tailorable mechanical properties.
Biofabrication,
3(2), 021001.
https://doi.org/10.1088/1758-5082/3/2/021001 Seyednejad, S. H., Ji, W.
, Schuurman, W., Dhert, W. J. A., Malda, J., Yang, F., Jansen, J. A.
, van Nostrum, C. F., Vermonden, T., & Hennink, W. E. (2011).
An electrospun degradable scaffold based on a novel hydrophilic polyester for tissue-engineering applications.
Macromolecular Bioscience,
11(12), 1684-1692.
https://doi.org/10.1002/mabi.201100229 Pescosolido, L., Vermonden, T., Malda, J., Censi, R., Dhert, W. J. A., Alhaique, F.
, Hennink, W. E., & Matricardi, P. (2011).
In situ forming IPN hydrogels of calcium alginate and dextran-HEMA for biomedical applications. Acta Biomaterialia,
7(4), 1627-1633.
https://doi.org/10.1016/j.actbio.2010.11.040 Catt, C. J.
, Schuurman, W., Sengers, B. G.
, van Weeren, P. R., Dhert, W. J. A., Please, C. P.
, & Malda, J. (2011).
Mathematical modelling of tissue formation in chondrocyte filter cultures. European Cells & Materials [E],
22, 377-392.
http://www.ncbi.nlm.nih.gov/pubmed/22179936Pescosolido, L., Schuurman, W., Malda, J., Matricardi, P., Alhaigue, F., Coviello, T.
, van Weeren, P. R., Dhert, W. J. A., Hennink, W. E., & Vermonden, T. (2011).
Hyaluronic acid and dextran-based semi-IPN hydrogels as biomaterials for bioprinting. Biomacromolecules,
12(5), 1831-1838.
https://doi.org/10.1021/bm200178w Other output
Schuurman, W., Khristov, V., Pot, M. W., van Weeren, P. R., Dhert, W. J. A., & Malda, J. (2011). Hybrid Bioprinting Technique to Generate Organized Constructs with Improved Mechanical Properties. Abstract from Dutch Society of Matrix Biology, Lunteren, the Netherlands.
Benders, K. E. M., Klein, T. J., de Grauw, J. C., Hutmacher, D. W., van Weeren, P. R., Saris, D. B. F., Dhert, W. J. A., & Malda, J. (2011). Depth-dependent Similarities of Equine and Human Osteochondral Tissue from the Femoral Condyles. Abstract from UK Matrix Biology meeting, Bristol, UK.
2010
Scholarly publications
Benders, K. E. M.
, Malda, J., Saris, D. B. F.
, Dhert, W. J. A., Steck, R., Hutmacher, D. W., & Klein, T. J. (2010).
Formalin fixation affects equilibrium partitioning of an ionic contrast agent-microcomputed tomography (EPIC-μCT) imaging of osteochondral samples.
Osteoarthritis and Cartilage,
18(12), 1586-1591.
https://doi.org/10.1016/j.joca.2010.10.005Malda, J., ten Hoope, W.
, Schuurman, W., van Osch, G. J. V. M.
, van Weeren, P. R., & Dhert, W. J. A. (2010).
Localization of the potential zonal marker clusterin in native cartilage and in tissue-engineered constructs. Tissue Engineering,
16(3), 897-904.
https://doi.org/10.1089/ten.tea.2009.0376 Bekkers, J. E. J., Tsuchida, A. I.
, Malda, J., Creemers, L. B., Castelein, R. M., Saris, D. B. F.
, & Dhert, W. J. A. (2010).
Quality of scaffold fixation in a human cadaver knee model. Osteoarthritis and Cartilage,
18(2), 266-272.
https://doi.org/10.1016/j.joca.2009.09.001Gawlitta, D., Farrell, E.
, Malda, J., Creemers, L. B., Alblas, J.
, & Dhert, W. J. A. (2010).
Modulating endochondral ossification of multipotent stromal cells for bone regeneration. Tissue Engineering,
16(4), 385-395.
https://doi.org/10.1089/ten.teb.2009.07122009
Scholarly publications
Borg, D. J., Dawson, R. A., Leavesley, D. I., Hutmacher, D. W., Upton, Z.
, & Malda, J. (2009).
Functional and phenotypic characterization of human keratinocytes expanded in microcarrier culture.
Journal of Biomedical Materials Research - Part A,
88(1), 184-94.
https://doi.org/10.1002/jbm.a.31864Shipley, R. J., Jones, G. W., Dyson, R. J., Sengers, B. G., Bailey, C. L., Catt, C. J., Please, C. P.
, & Malda, J. (2009).
Design criteria for a printed tissue engineering construct: a mathematical homogenization approach.
Journal of Theoretical Biology,
259(3), 489-502.
https://doi.org/10.1016/j.jtbi.2009.03.037Klein, T. J.
, Malda, J., Sah, R. L., & Hutmacher, D. W. (2009).
Tissue engineering of articular cartilage with biomimetic zones.
Tissue Engineering - Part B: Reviews,
15(2), 143-57.
https://doi.org/10.1089/ten.TEB.2008.0563Ainscough, S. L., Feigl, B.
, Malda, J., & Harkin, D. G. (2009).
Discovery and characterization of IGFBP-mediated endocytosis in the human retinal pigment epithelial cell line ARPE-19.
Experimental Eye Research,
89(5), 629-37.
https://doi.org/10.1016/j.exer.2009.06.005Woodfield, T. B. F., Moroni, L., & Malda, J. (2009). Combinatorial approaches to controlling cell behaviour and tissue formation in 3D via rapid-prototyping and smart scaffold design. Combinatorial chemistry & high throughput screening, 12(6), 562-79.
Klein, T. J., Rizzi, S. C., Reichert, J. C., Georgi, N.
, Malda, J., Schuurman, W., Crawford, R. W., & Hutmacher, D. W. (2009).
Strategies for zonal cartilage repair using hydrogels. Macromolecular Bioscience,
9(11), 1049-1058.
https://doi.org/10.1002/mabi.200900176Rouwkema, J., Koopman, B. F. J. M., van Blitterswijk, C. A., Dhert, W. J. A., & Malda, J. (2009). Supply of nutrients to cells in engineered tissues. Biotechnology & Genetic Engineering Reviews, 26, 175-190.
Schuurman, W., Gawlitta, D., Klein, T. J., ten Hoope, W., van Rijen, M. H. P.
, Dhert, W. J. A., van Weeren, P. R., & Malda, J. (2009).
Zonal chondrocyte subpopulations reacquire zone-specific characteristics during in vitro redifferentiation. American Journal of Sports Medicine,
37(Suppl. 1), 97S-104S.
https://doi.org/10.1177/0363546509350978 Other output
Klein, T. J., Rizzi, S. C., Reichert, J. C., Georgi, N.
, Malda, J., Schuurman, W., Crawford, R. W., & Hutmacher, D. W. (2009).
Cover Picture Macromolecular Bioscience 11/2009. Macromolecular Bioscience.
https://doi.org/10.1002/mabi.2009900232008
Scholarly publications
Upton, Z., Cuttle, L., Noble, A., Kempf, M., Topping, G.
, Malda, J., Xie, Y., Mill, J., Harkin, DG., Kravchuk, O., Leavesley, DI., & Kimble, RM. (2008).
Vitronectin: growth factor complexes hold potential as a wound therapy approach. Journal of Investigative Dermatology,
128(6).
https://doi.org/10.1038/sj.jid.5701148Malda, J., Rouwkema, J., Leeuwenburgh, S. C. G.
, Dhert, W. J. A., & Kirkpatrick, C. J. (2008).
Crossing frontiers in biomaterials and regenerative medicine. 8th World Biomaterials Congress, 28 May - 1 June, Amsterdam, The Netherlands.
Regenerative Medicine,
3(5), 765-8.
https://doi.org/10.2217/17460751.3.5.765 Leeuwenburgh, S. C. G.
, Jansen, J. A., Malda, J., Dhert, W. A., Rouwkema, J., van Blitterswijk, C. A., Kirkpatrick, C. J., & Williams, D. F. (2008).
Trends in biomaterials research: An analysis of the scientific programme of the World Biomaterials Congress 2008.
Biomaterials,
29(21), 3047-52.
https://doi.org/10.1016/j.biomaterials.2008.04.032Fernandez, M. L., Broadbent, J. A., Shooter, G. K.
, Malda, J., & Upton, Z. (2008).
Development of an enhanced proteomic method to detect prognostic and diagnostic markers of healing in chronic wound fluid.
British Journal of Dermatology,
158(2), 281-90.
https://doi.org/10.1111/j.1365-2133.2007.08362.x2007
Scholarly publications
Wu, D.
, Malda, J., Crawford, R., & Xiao, Y. (2007).
Effects of hyperbaric oxygen on proliferation and differentiation of osteoblasts from human alveolar bone.
Connective Tissue Research,
48(4), 206-13.
https://doi.org/10.1080/030082007014587492006
Scholarly publications
Dawson, R. A., Upton, Z.
, Malda, J., & Harkin, D. G. (2006).
Preparation of cultured skin for transplantation using insulin-like growth factor I in conjunction with insulin-like growth factor binding protein 5, epidermal growth factor, and vitronectin.
Transplantation,
81(12), 1668-76.
https://doi.org/10.1097/01.tp.0000226060.51572.89Radisic, M.
, Malda, J., Epping, E., Geng, WL., Langer, R., & Vunjak-Novakovic, G. (2006).
Oxygen gradients correlate with cell density and cell viability in engineered cardiac tissue.
Biotechnology and Bioengineering,
93(2), 332-343.
https://doi.org/10.1002/bit.207222005
Scholarly publications
Lewis, M. C., Macarthur, B. D.
, Malda, J., Pettet, G., & Please, C. P. (2005).
Heterogeneous proliferation within engineered cartilaginous tissue: the role of oxygen tension.
Biotechnology and Bioengineering,
91(5), 607-15.
https://doi.org/10.1002/bit.20508Malda, J., Woodfield, T. B. F., van der Vloodt, F., Wilson, C., Martens, D. E., Tramper, J., van Blitterswijk, C. A., & Riesle, J. (2005).
The effect of PEGT/PBT scaffold architecture on the composition of tissue engineered cartilage.
Biomaterials,
26(1), 63-72.
https://doi.org/10.1016/j.biomaterials.2004.02.046 2004
Scholarly publications
Malda, J., van den Brink, P., Meeuwse, P., Grojec, M., Martens, D. E., Tramper, J., Riesle, J., & van Blitterswijk, C. A. (2004).
Effect of oxygen tension on adult articular chondrocytes in microcarrier bioreactor culture.
Tissue Engineering,
10(7-8), 987-94.
https://doi.org/10.1089/ten.2004.10.987 Malda, J., Woodfield, T. B. F., van der Vloodt, F., Kooy, F. K., Martens, D. E., Tramper, J., van Blitterswijk, C. A., & Riesle, J. (2004).
The effect of PEGT/PBT scaffold architecture on oxygen gradients in tissue engineered cartilaginous constructs.
Biomaterials,
25(26), 5773-80.
https://doi.org/10.1016/j.biomaterials.2004.01.028 Woodfield, T. B. F.
, Malda, J., de Wijn, J.
, Péters, F., Riesle, J., & van Blitterswijk, C. A. (2004).
Design of porous scaffolds for cartilage tissue engineering using a three-dimensional fiber-deposition technique.
Biomaterials,
25(18), 4149-61.
https://doi.org/10.1016/j.biomaterials.2003.10.056Malda, J., van Blitterswijk, C. A., van Geffen, M., Martens, D. E., Tramper, J., & Riesle, J. (2004).
Low oxygen tension stimulates the redifferentiation of dedifferentiated adult human nasal chondrocytes.
Osteoarthritis and Cartilage,
12(4), 306-13.
https://doi.org/10.1016/j.joca.2003.12.001 Malda, J., Rouwkema, J., Martens, D. E., Le Comte, E. P., Kooy, F. K., Tramper, J., van Blitterswijk, C. A., & Riesle, J. (2004).
Oxygen gradients in tissue-engineered PEGT/PBT cartilaginous constructs: measurement and modeling.
Biotechnology and Bioengineering,
86(1), 9-18.
https://doi.org/10.1002/bit.20038 2003
Scholarly publications
Malda, J., Martens, DE., Tramper, J., van, B. CA., & Riesle, J. (2003). Cartilage tissue engineering: controversy in the effect of oxygen. Critical Reviews in Biotechnology, 23(3), 175-194.
Malda, J., van Blitterswijk, C. A., Grojec, M., Martens, D. E., Tramper, J., & Riesle, J. (2003).
Expansion of bovine chondrocytes on microcarriers enhances redifferentiation.
Tissue Engineering,
9(5), 939-48.
https://doi.org/10.1089/107632703322495583 Malda, J., Kreijveld, E., Temenoff, J. S., van Blitterswijk, C. A., & Riesle, J. (2003).
Expansion of human nasal chondrocytes on macroporous microcarriers enhances redifferentiation.
Biomaterials,
24(28), 5153-61.
https://doi.org/10.1016/s0142-9612(03)00428-9