The Hindon sub-basin, part of the Gangetic Plain, suffers from water depletion and pollution due to over-extraction and emissions by agriculture and other sectors. With relevant stakeholders in the Hindon sub-basin, the contribution of agriculture and other sectors to problems with water quantity and quality will be determined. The origins of water flows and pollutants, particularly nitrate and lead, will be traced with isotope analysis. Stakeholders and researchers will identify alternative agricultural management options to improve water use efficiency and to reduce emissions by agriculture. Using spatially explicit models for trade-off analysis, these will be evaluated and visualised at the levels of fields, farms, landscapes, and the whole sub-basin. A vision of future development will be formulated and steps for its implementation will be identified and started.