Publications
2023
Scholarly publications
Zaree, P., Tomris, I., de Vos, S. D., van der Woude, R., Flesch, F. M., Klein Gebbink, R. J. M., de Vries, R. P., & Pieters, R. J. (2023). Facile electrochemical affinity measurements of small and large molecules. RSC Advances, 13(14), 9756-9760. https://doi.org/10.1039/d3ra01029e
2021
Scholarly publications
Zaree, P., Torano, J. S., de Haan, C. A. M., Scheltma, R. A., Barendregt, A., Thijssen, V., Yu, G., Flesch, F., & Pieters, R. J. (2021). The assessment of Pseudomonas aeruginosa lectin LecA binding characteristics of divalent galactosides using multiple techniques. Glycobiology, 31(11), 1490-1499. https://doi.org/10.1093/glycob/cwab074
2017
Scholarly publications
Mackus, M., van de Loo, A. J. A. E., Raasveld, S. J., Hogewoning, A., Sastre Toraño, J., Flesch, F. M., Korte-Bouws, G. A. H., van Neer, R. H. P., Wang, X., Nguyen, T. T., Brookhuis, K. A., Kraneveld, A. D., Garssen, J., & Verster, J. C. (2017). Biomarkers of the alcohol hangover state: Ethyl glucuronide (EtG) and ethyl sulfate (EtS). Human Psychopharmacology, 32(5), [2624]. https://doi.org/10.1002/hup.2624
2015
Scholarly publications
Jordan, N. Y., Mimpen, J. Y., van den Bogaard, W. J. M., Flesch, F. M., van de Meent, M. H. M., & Torano, J. S. (2015). Analysis of caffeine and paraxanthine in human saliva with ultra-high-performance liquid chromatography for CYP1A2 phenotyping. Journal of chromatography. B, 995, 70-73. https://doi.org/10.1016/j.jchromb.2015.05.020
2013
Scholarly publications
Haselberg, R., Flesch, F. M., Boerke, A., & Somsen, G. W. (2013). Thickness and morphology of polyelectrolyte coatings on silica surfaces before and after protein exposure studied by atomic force microscopy. Analytica Chimica Acta, 779, 90-95.
2011
Professional publications
Meijerman, I., ten Berge, H., Wisman, G., Oussoren, C., Stroink, T., Flesch, F. M., & Koster, A. S. (2011). Interne onderwijsdifferentiatie in een bachelor Farmacie cursus. Onderzoek van Onderwijs, 40, 28-33.
2008
Scholarly publications
Hofman, J-W., Carstens, M. G., Van Zeeland, F., Helwig, C., Flesch, F. M., Hennink, W. E., & Van Nostrum, C. F. (2008). Photocytotoxicity of mTHPC (temoporfin) loaded polymeric micelles mediated by lipase catalyzed degradation. Pharmaceutical Research, 25(9), 2065-2073. https://doi.org/10.1007/s11095-008-9590-7
Fens, M. H. A. M., Mastrobattista, E., De Graaff, A. M., Flesch, F. M., Ultee, A., Rasmussen, J. T., Molema, G., Storm, G., & Schiffelers, R. M. (2008). Angiogenic endothelium shows lactadherin-dependent phagocytosis of aged erythrocytes and apoptotic cells. Blood, 111(9), 4542-4550. https://doi.org/10.1182/blood-2007-06-094763
Fens, M. H. A. M., Mastrobattista, E., de Graaff, A. M., Flesch, F. M., Ultee, A., Rasmussen, J., Molema, G., Storm, G., & Schiffelers, R. M. (2008). Angiogenic dndothelium shows lactadherin-dependent phagocytosis of aged erythrocytes and apoptotic cells. Blood, 111(9), 4542-4550.
https://dspace.library.uu.nl/bitstream/handle/1874/37414/2008%252329.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/37414/2008%252329.pdf?sequence=1
Romberg, B., Flesch, F. M., Hennink, W. E., & Storm, G. (2008). Enzyme-induced shedding of a poly(amino acid)-coating triggers contents release from dioleoyl phosphatidylethanolamine liposomes. International Journal of Pharmaceutics, 355, 108-113.
Hofman, J. W., Carstens, M. G., van Zeeland, F., Helwig, C., Flesch, F. M., Hennink, W. E., & van Nostrum, C. F. (2008). Photocytotoxicity of mTHPC (temoporfin) loaded oligomeric micelles mediated by lipase catalyzed degradation. Pharmaceutical Research, 25, 2065-2073.
Beijnen, J. H., van der Schoot, S. C., Nuijen, B., Flesch, F. M., Gore, A., Mirejovsky, D., & Lenaz, L. (2008). Complexation study of the anticancer agent EO-9 with 2-hydroxypropyl-beta-cyclodextrin. Drug Development and Industrial Pharmacy, 34(10), 1130-1139.
2007
Scholarly publications
Carstens, M. G., Bevernage, J. J. L., van Nostrum, C. F., van Steenbergen, M. J., Flesch, F. M., Verrijk, R., de Leede, L., Crommelin, D. J. A., & Hennink, W. E. (2007). Small oligomeric micelles based on end group modified mPeg-oligocaprolactone with monodisperse hydrophobic blocks. Macromolecules, 40, 116-122.
van der Schoot, S. C., Nuijen, B., Flesch, F. M., Gore, A., Mirejovsky, D., Lenaz, L., & Beijnen, J. H. (2007). Development of a bladder instillation of the indoloquinone anticancer agent EO-9 using tert-butyl alcohol as lyophilization vehicle. AAPS PharmSciTech, 8(3).
van Hell, A. J., Costa, C. I. C. A., Flesch, F. M., Sutter, M., Jiskoot, W., Crommelin, D. J. A., Hennink, W. E., & Mastrobattista, E. (2007). Self-assembly of recombinant amphiphilic oligopeptides into vesicles. Biomacromolecules, 8, 2753-2761.
2006
Scholarly publications
Schillemans, J. P., Flesch, F. M., Hennink, W. E., & Van Nostrum, C. F. (2006). Synthesis of bilayer-coated nanogels by selective cross-linking of monomers inside liposomes. Macromolecules, 39(17), 5885-5890. https://doi.org/10.1021/ma060727t
Schillemans, J. P., Flesch, F. M., Hennink, W. E., & van Nostrum, C. F. (2006). Synthesis of bilayer-coated nanogels by selective crosslinking of monomers inside liposomes. Macromolecules, 39, 5885-5890.
2005
Scholarly publications
Flesch, F. M., Yu, J. W., Lemmon, M. A., & Burger, K. N. (2005). Membrane activity of the phospholipase C-delta1 pleckstrin homology (PH) domain. Biochemical Journal, 389, 435-441.
Van Thienen, T. G., Lucas, B., Flesch, F. M., van Nostrum, C. F., Demeester, J., & de Smedt, S. C. (2005). On the synthesis and characterization of biodegradable dextran nanogels with tunable degradation properties. Macromolecules, 38(20), 8503-8511.
2003
Scholarly publications
Lefievre, L., Barratt, C. L., Harper, C. V., Conner, S. J., Flesch, F. M., Deeks, E., Moseley, F. L. C., Pixton, K. L., Brewis, I. A., & Publicover, S. J. (2003). Physiological and proteomic approaches to studying prefertilization events in the human. Reproductive BioMedicine Online, 7, 419-427.
Other output
Pixton, K. L., Deeks, E. D., Flesch, F. M., Barratt, C. L., & Brewis, I. A. (2003). Proteomic approaches to study human spermatozoa in fertile and infertile men. Abstract from Unknown event, Asilomar, USA.
2001
Scholarly publications
Flesch, F. M., Brouwers, J. F. H. M., Nievelstein, P. F. E. M., Verkleij, A. J., van Golde, L. M. G., Colenbrander, B. A., & Gadella, B. M. (2001). Bicarbonate stimulated phospholipid scrambling induces cholesterol redistribution and enables cholesterol depletion in the sperm plasma membrane. Journal of Cell Science, 114, 3543-3555.
Flesch, F. M., Wijnand, E., van de Lest, C. H. A., Colenbrander, B. A., van Golde, L. M. G., & Gadella, B. M. (2001). Capacitation dependent activation of tyrosine phosphorylation generates two sperm head plasma membrane proteins with high primary binding affinity for the zona pellucida. Molecular Reproduction and Development, 60, 107-115.
2000
Scholarly publications
Flesch, F. M. (2000). Capacitation dependent changes in the sperm plasma membrane influence porcine gamete interaction. [Doctoral thesis 1 (Research UU / Graduation UU), Utrecht University].
Revah, I., Gadella, B. M., Flesch, F. M., & Colenbrander, B. A. (2000). Physiological state of bull sperm affects fucose- and mannose-binding properties. Biology of Reproduction, 62, 1010-1015.
Revah, I., Gadella, B. M., Flesch, F. M., Colenbrander, B. A., & Suarez, S. S. (2000). The physiological state of bull sperm affect fructose en mannose-binding properties. Biology of Reproduction, 62, 1010-1015.
Flesch, F. M., Colenbrander, B. A., van Golde, L. M. G., & Gadella, B. M. (2000). Capacitation induced molecular alterations in the plasma membrane of boar spermatozoa in relation to zona affinity. In L. A. Johnson, & H. D. Guthrie (Eds.), Boar Semen Preservation IV (pp. 21-31). Allen Press Inc..
Flesch, F. M., & Gadella, B. M. (2000). Dynamics of the mammalian sperm membrane in the process of fertilization. Biochimica et Biophysica Acta, 469(3), 197-235.
1996
Scholarly publications
Van Hellemond, J. J., Luijten, M., Flesch, F. M., Gaasenbeek, C. P., & Tielens, A. G. (1996). Rhodoquinone is synthesized de novo by Fasciola hepatica. Molecular and Biochemical Parasitology, 82(2), 217-226. https://doi.org/10.1016/0166-6851(96)02738-7