Publications
2022
Scholarly publications
van den Berg, R., Mastrobattista, E., & Jiskoot, W. (2022).
Claiming therapeutic protein stability in a clinical setting based on limited analytical data is misleading and dangerous.
American Journal of Health-System Pharmacy,
79(8), 622-623.
https://doi.org/10.1093/ajhp/zxab465 Rousou, C., de Maar, J.
, Qiu, B., van der Wurff-Jacobs, K., Ruponen, M., Urtti, A.
, Oliveira, S., Moonen, C.
, Storm, G., Mastrobattista, E., & Deckers, R. (2022).
The Effect of Microbubble-Assisted Ultrasound on Molecular Permeability across Cell Barriers.
Pharmaceutics,
14(3).
https://doi.org/10.3390/pharmaceutics14030494 Bouzetos, E., Ganar, K. A.
, Mastrobattista, E., Deshpande, S., & van der Oost, J. (2022).
(R)evolution-on-a-chip.
Trends in Biotechnology,
40(1), 60-76.
https://doi.org/10.1016/j.tibtech.2021.04.009Evers, M. J. W., Du, W., Yang, Q.
, Kooijmans, S. A. A., Vink, A.
, van Steenbergen, M., Vader, P., de Jager, S. C. A., Fuchs, S. A.
, Mastrobattista, E., Sluijter, J. P. G., Lei, Z.
, & Schiffelers, R. (2022).
Delivery of modified mRNA to damaged myocardium by systemic administration of lipid nanoparticles.
Journal of Controlled Release,
343, 207-216.
https://doi.org/10.1016/j.jconrel.2022.01.027 Walther, J., Wilbie, D., Tissingh, V. S. J., Öktem, M., Van Der Veen, H.
, Lou, B., & Mastrobattista, E. (2022).
Impact of Formulation Conditions on Lipid Nanoparticle Characteristics and Functional Delivery of CRISPR RNP for Gene Knock-Out and Correction.
Pharmaceutics,
14(1), [213].
https://doi.org/10.3390/pharmaceutics14010213 Rousou, C., De Maar, J.
, Qiu, B., Van Der Wurff-Jacobs, K., Ruponen, M., Urtti, A.
, Oliveira, S., Moonen, C.
, Storm, G., Mastrobattista, E., & Deckers, R. (2022).
The Effect of Microbubble-Assisted Ultrasound on Molecular Permeability across Cell Barriers.
Pharmaceutics,
14(3), [494].
https://doi.org/10.3390/pharmaceutics14030494 Lau, C. Y. J.
, Benne, N., Lou, B., Braake, D. T., Bosman, E., van Kronenburg, N., Fens, M., Broere, F., Hennink, W. E., & Mastrobattista, E. (2022).
Tuning surface charges of peptide nanofibers for induction of antigen-specific immune tolerance: an introductory study.
Journal of Pharmaceutical Sciences,
111(4), 1004-1011.
https://doi.org/10.1016/j.xphs.2022.01.0302021
Scholarly publications
Raes, L., Pille, M., Harizaj, A., Goetgeluk, G., Van Hoeck, J., Stremersch, S., Fraire, J. C., Brans, T.
, de Jong, O. G., Maas-Bakker, R., Mastrobattista, E., Vader, P., De Smedt, S. C., Vandekerckhove, B., Raemdonck, K., & Braeckmans, K. (2021).
Cas9 RNP transfection by vapor nanobubble photoporation for
ex vivo cell engineering. Molecular Therapy - Nucleic Acids,
25, 696-707.
https://doi.org/10.1016/j.omtn.2021.08.014Lou, B., Lau, C. Y. J., Hennink, W. E., & Mastrobattista, E. (2021).
Preparation of mRNA Polyplexes with Post-conjugated Endosome-Disruptive Peptides. In W. M. Hussein, R. J. Stephenson, & I. Toth (Eds.),
Peptide Conjugation: Methods and Protocols (1 ed., pp. 275-286). (Methods in Molecular Biology; Vol. 2355). Humana, New York, NY.
https://doi.org/10.1007/978-1-0716-1617-8_21 Rousou, C., Schuurmans, C. C. L., Urtti, A.
, Mastrobattista, E., Storm, G., Moonen, C., Kaarniranta, K.
, & Deckers, R. (2021).
Ultrasound and Microbubbles for the Treatment of Ocular Diseases: From Preclinical Research towards Clinical Application.
Pharmaceutics,
13(11), 1-35. [1782].
https://doi.org/10.3390/pharmaceutics13111782 Mastrobattista, E. (2021).
Formulation and delivery solutions for the next generation biotherapeutics.
Journal of controlled release : official journal of the Controlled Release Society,
336, 583-597.
https://doi.org/10.1016/j.jconrel.2021.06.029 Jarusintanakorn, S., Phechkrajang, C., Khongkaew, P.
, Mastrobattista, E., & Yamabhai, M. (2021).
Determination of Chinese hamster ovary (CHO) cell densities and antibody titers from small volumes of cell culture supernatants using multivariate analysis and partial least squares regression of UV-Vis spectra.
Analytical and Bioanalytical Chemistry,
413(23), 5743-5753.
https://doi.org/10.1007/s00216-021-03549-4 Crommelin, D. J. A., Anchordoquy, T. J., Volkin, D. B., Jiskoot, W.
, & Mastrobattista, E. (2021).
Addressing the Cold Reality of mRNA Vaccine Stability.
Journal of Pharmaceutical Sciences,
110(3), 997-1001.
https://doi.org/10.1016/j.xphs.2020.12.006 Ter Braake, D., Benne, N., Lau, C. Y. J.
, Mastrobattista, E., & Broere, F. (2021).
Retinoic Acid-Containing Liposomes for the Induction of Antigen-Specific Regulatory T Cells as a Treatment for Autoimmune Diseases.
Pharmaceutics,
13(11), 1-17. [1949].
https://doi.org/10.3390/pharmaceutics13111949 Raes, L., Pille, M., Harizaj, A., Goetgeluk, G., van Hoeck, J., Stremersch, S., Fraire, J. C., Brans, T.
, de Jong, O. G., Maas - Bakker, R., Mastrobattista, E., Vader, P., de Smedt, S. C., Vandekerckhove, B., Raemdonck, K., & Braeckmans, K. (2021).
Cas9 RNP transfection by vapor nanobubble photoporation for ex vivo cell engineering.
Molecular Therapy - Nucleic Acids,
25, 696-707.
https://doi.org/10.1016/j.omtn.2021.08.014Jerry Lau, C. Y., & Mastrobattista, E. (2021).
Programming supramolecular peptide materials by modulating the intermediate steps in the complex assembly pathway: implications for biomedical applications.
Current opinion in colloid & interface science,
51, 1-10. [101396].
https://doi.org/10.1016/j.cocis.2020.101396 2020
Scholarly publications
Oude Blenke, E., Mahakena, S.
, Fens, M., van den Dikkenberg, J., Holkers, M.
, & Mastrobattista, E. (2020).
Impact of chemistry and nanoformulation parameters on cellular uptake and airway distribution of RNA oligonucleotides.
Journal of controlled release : official journal of the Controlled Release Society,
317, 154-165.
https://doi.org/10.1016/j.jconrel.2019.11.025 Crommelin, D. J. A., Mastrobattista, E., Hawe, A., Hoogendoorn, K. H., & Jiskoot, W. (2020).
Shifting Paradigms Revisited: Biotechnology and the Pharmaceutical Sciences.
Journal of Pharmaceutical Sciences,
109(1), 30-43.
https://doi.org/10.1016/j.xphs.2019.08.010 Aldosari, M. H., den Hartog, M., Ganizada, H., Evers, M. J. W.
, Mastrobattista, E., & Schellekens, H. (2020).
Feasibility Study for Bedside Production of Recombinant Human Acid α-Glucosidase: Technical and Financial Considerations.
Current Pharmaceutical Biotechnology,
21(6), 467-479.
https://doi.org/10.2174/1389201021666200217113049 Lau, C. Y. J., Fontana, F.
, Mandemaker, L. D. B., Wezendonk, D., Vermeer, B.
, Bonvin, A. M. J. J., de Vries, R., Zhang, H., Remaut, K.
, van den Dikkenberg, J., Medeiros-Silva, J., Hassan, A., Perrone, B., Kuemmerle, R., Gelain, F.
, Hennink, W. E., Weingarth, M., & Mastrobattista, E. (2020).
Author Correction: Control over the fibrillization yield by varying the oligomeric nucleation propensities of self-assembling peptides.
Communications Chemistry,
3(1), [179].
https://doi.org/10.1038/s42004-020-00436-4Lau, C. Y. J., Fontana, F., Mandemaker, L. D. B., Wezendonk, D., Vermeer, B.
, Bonvin, A. M. J. J., De Vries, R., Zhang, H., Remaut, K.
, Van Den Dikkenberg, J., Medeiros-silva, J., Hassan, A., Perrone, B., Kuemmerle, R., Gelain, F.
, Hennink, W. E., Weingarth, M., & Mastrobattista, E. (2020).
Control over the fibrillization yield by varying the oligomeric nucleation propensities of self-assembling peptides.
Communications Chemistry,
3(1), [164].
https://doi.org/10.1038/s42004-020-00417-7 Kloos, R., van der Sluis, I. M.
, Mastrobattista, E., Hennink, W., Pieters, R.
, & Verhoef, J-J. (2020).
Acute lymphoblastic leukaemia patients treated with PEGasparaginase develop antibodies to PEG and the succinate linker.
British Journal of Haematology,
189(3), 442-451.
https://doi.org/10.1111/bjh.162542019
Scholarly publications
Schiffelers, R. M., Oude Blenke, E., & Mastrobattista, E. (2019).
Oligonucleotides. In
Pharmaceutical Biotechnology: Fundamentals and Applications (pp. 305-322). Springer International Publishing AG.
https://doi.org/10.1007/978-3-030-00710-2_15 Jiskoot, W., Kersten, G. F. A.
, Mastrobattista, E., & Slütter, B. (2019).
Vaccines. In
Pharmaceutical Biotechnology: Fundamentals and Applications (pp. 282-304). Springer International Publishing AG.
https://doi.org/10.1007/978-3-030-00710-2_14 Leneweit, G., Miranda, B. S.
, de Matos, M. B. C., Beztsinna, N., Heyder, C., Dührkop, C., Nirschl, H., Ekdahl, K. N., Nilsson, B.
, Mastrobattista, E., & Kok, R. J. (2019).
Colloidal formulation of mistletoe extracts in a pharmaceutical flow process for targeted cancer therapy.
Phytomedicine,
61(Supplement 1).
https://doi.org/10.1016/j.phymed.2019.09.118Willems, L., Van Westerveld, L., Roberts, S., Weitzhandler, I., Calcines Cruz, C., Hernandez-Garcia, A., Chilkoti, A.
, Mastrobattista, E., Van Der Oost, J., & De Vries, R. (2019).
Nature of amorphous hydrophilic block affects self-assembly of an artificial viral coat polypeptide.
Biomacromolecules,
20(10), 3641-3647.
https://doi.org/10.1021/acs.biomac.9b00512Kordalivand, N., Tondini, E.
, Lau, C. Y. J., Vermonden, T., Mastrobattista, E., Hennink, W. E., Ossendorp, F.
, & Nostrum, C. F. V. (2019).
Cationic synthetic long peptides-loaded nanogels: An efficient therapeutic vaccine formulation for induction of T-cell responses.
Journal of Controlled Release,
315, 114-125.
https://doi.org/10.1016/j.jconrel.2019.10.048 Kontturi, L. S., Van Den Dikkenberg, J., Urtti, A.
, Hennink, W. E., & Mastrobattista, E. (2019).
Light-triggered cellular delivery of oligonucleotides.
Pharmaceutics,
11(2), [90].
https://doi.org/10.3390/pharmaceutics11020090 Lou, B., Connor, K., Sweeney, K., Miller, I. S., O’Farrell, A.
, Ruiz-Hernandez, E., Murray, D. M., Duffy, G. P.
, Wolfe, A., Mastrobattista, E., Byrne, A. T.
, & Hennink, W. E. (2019).
RGD-decorated cholesterol stabilized polyplexes for targeted siRNA delivery to glioblastoma cells.
Drug Delivery and Translational Research,
9(3), 679-693.
https://doi.org/10.1007/s13346-019-00637-y Willems, L., Roberts, S., Weitzhandler, I., Chilkoti, A.
, Mastrobattista, E., Van Der Oost, J., & De Vries, R. (2019).
Inducible Fibril Formation of Silk-Elastin Diblocks.
ACS Omega,
4(5), 9135-9143.
https://doi.org/10.1021/acsomega.9b01025Aldosari, M. H., de Vries, R. P., Rodriguez, L. R., Hesen, N. A.
, Beztsinna, N., van Kuilenburg, A. B. P., Hollak, C. E. M.
, Schellekens, H., & Mastrobattista, E. (2019).
Liposome-targeted recombinant human acid sphingomyelinase: Production, formulation, and in vitro evaluation.
European Journal of Pharmaceutics and Biopharmaceutics,
137, 185-195.
https://doi.org/10.1016/j.ejpb.2019.02.019 Rousou, C., Hoogenboom, P., van Overdam, K. A.
, Storm, G., Dorrestijn, J.
, & Mastrobattista, E. (2019).
A technical protocol for an experimental ex vivo model using arterially perfused porcine eyes.
Experimental Eye Research,
181, 171-177.
https://doi.org/10.1016/j.exer.2019.02.003 Lou, B., De Beuckelaer, A., Boonstra, E.
, Li, D., De Geest, B. G., De Koker, S.
, Mastrobattista, E., & Hennink, W. E. (2019).
Modular core-shell polymeric nanoparticles mimicking viral structures for vaccination.
Journal of Controlled Release,
293, 48-62.
https://doi.org/10.1016/j.jconrel.2018.11.006 2018
Scholarly publications
Ljeskovic, N. J., Blauuw, M., Talsma, H., Koster, A., & Mastrobattista, E. (2018). When e-learning replaces the classroom: Lessons learned during the development process of an online biotechnology course. Pharmacy Education, 18(1), 19-20.
Lou, B., De Beuckelaer, A., Dakwar, G. R., Remaut, K., Grooten, J., Braeckmans, K.
, De Geest, B. G., Mastrobattista, E., De Koker, S.
, & Hennink, W. E. (2018).
Post-PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties.
Journal of Controlled Release,
284, 73-83.
https://doi.org/10.1016/j.jconrel.2018.06.010 Cao, S., Abdelmohsen, L. K. E. A., Shao, J.
, Van Den Dikkenberg, J., Mastrobattista, E., Williams, D. S., & Van Hest, J. C. M. (2018).
PH-Induced Transformation of Biodegradable Multilamellar Nanovectors for Enhanced Tumor Penetration.
ACS Macro Letters,
7(11), 1394-1399.
https://doi.org/10.1021/acsmacrolett.8b00807 Lou, B., De Koker, S.
, Lau, C. Y. J., Hennink, W. E., & Mastrobattista, E. (2018).
MRNA Polyplexes with Post-Conjugated GALA Peptides Efficiently Target, Transfect, and Activate Antigen Presenting Cells.
Bioconjugate Chemistry.
https://doi.org/10.1021/acs.bioconjchem.8b00524 de Matos, M. B. C., Beztsinna, N., Heyder, C., Fens, M. H. A. M., Mastrobattista, E., Schiffelers, R. M., Leneweit, G.
, & Kok, R. J. (2018).
Thermosensitive liposomes for triggered release of cytotoxic proteins.
European Journal of Pharmaceutics and Biopharmaceutics,
132, 211-221.
https://doi.org/10.1016/j.ejpb.2018.09.010 Beztsinna, N., de Matos, M. B. C., Walther, J., Heyder, C., Hildebrandt, E., Leneweit, G.
, Mastrobattista, E., & Kok, R. J. (2018).
Quantitative analysis of receptor-mediated uptake and pro-apoptotic activity of mistletoe lectin-1 by high content imaging.
Scientific Reports,
8(1), [2768].
https://doi.org/10.1038/s41598-018-20915-y Oude Blenke, E., Evers, M. J. W., Baumann, V., Winkler, J.
, Storm, G., & Mastrobattista, E. (2018).
Critical evaluation of quantification methods for oligonucleotides formulated in lipid nanoparticles.
International Journal of Pharmaceutics,
548(2), 793-802.
https://doi.org/10.1016/j.ijpharm.2017.12.035 Kordalivand, N., Li, D., Beztsinna, N., Sastre Torano, J., Mastrobattista, E., van Nostrum, C. F., Hennink, W. E., & Vermonden, T. (2018).
Polyethyleneimine coated nanogels for the intracellular delivery of RNase A for cancer therapy.
Chemical Engineering Journal,
340, 32-41.
https://doi.org/10.1016/j.cej.2017.12.071 2017
Scholarly publications
Schellekens, H., Aldosari, M., Talsma, H., & Mastrobattista, E. (2017).
Erratum: Making individualized drugs a reality.
Nature Biotechnology,
35(8), 797.
https://doi.org/10.1038/nbt0817-797c Guan, J., Sun, J.
, Sun, F., Lou, B., Zhang, D.
, Mashayekhi, V., Sadeghi, N., Storm, G., Mastrobattista, E., & He, Z. (2017).
Hypoxia-induced tumor cell resistance is overcome by synergistic GAPDH-siRNA and chemotherapy co-delivered by long-circulating and cationic-interior liposomes.
Nanoscale,
9(26), 9190-9201 .
https://doi.org/10.1039/C7NR02663C Schellekens, H., Aldosari, M., Talsma, H., & Mastrobattista, E. (2017).
Making individualized drugs a reality.
Nature Biotechnology,
35(6), 507-513.
https://doi.org/10.1038/nbt.3888 Li, D., Chen, Y., Mastrobattista, E., Van Nostrum, C. F., Hennink, W. E., & Vermonden, T. (2017).
Reduction-sensitive polymer-shell-coated nanogels for intracellular delivery of antigens.
ACS Biomaterials Science and Engineering,
3(1), 42-48.
https://doi.org/10.1021/acsbiomaterials.6b00651 Oude Blenke, E., Sleszynska, M., Evers, M. J. W.
, Storm, G., Martin, N., & Mastrobattista, E. (2017).
Strategies for the Activation and Release of the Membranolytic Peptide Melittin from Liposomes Using Endosomal pH as a Trigger.
Bioconjugate Chemistry,
28(2), 574-582.
https://doi.org/10.1021/acs.bioconjchem.6b00677 Tüysüz, N., van Bloois, L., van den Brink, S., Begthel, H., Verstegen, M. M. A., Cruz, L. J., Hui, L., van der Laan, L. J. W., de Jonge, J., Vries, R., Braakman, E.
, Mastrobattista, E., Cornelissen, J. J.
, Clevers, H., & Ten Berge, D. (2017).
Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells.
Nature Communications,
8, [14578].
https://doi.org/10.1038/ncomms14578 Radmalekshahi, M., Fransen, M. F., Krawczyk, M.
, Mansourian, M., Bourajjaj, M., Chen, J., Ossendorp, F.
, Hennink, W. E., Mastrobattista, E., & Amidi, M. (2017).
Self-Assembling Peptide Epitopes as Novel Platform for Anticancer Vaccination.
Molecular Pharmaceutics,
14, 1482-1493.
https://doi.org/10.1021/acs.molpharmaceut.6b01003 Li, D., van Nostrum, C. F., Mastrobattista, E., Vermonden, T., & Hennink, W. E. (2017).
Nanogels for intracellular delivery of biotherapeutics.
Journal of Controlled Release,
259, 16-28.
https://doi.org/10.1016/j.jconrel.2016.12.020 2016
Scholarly publications
Jiskoot, W., Kersten, G. F. A., & Mastrobattista, E. (2016). Vaccines. In Pharmaceutical Biotechnology: Fundamentals and Applications, Third Edition (pp. 405-427). CRC Press.
Rad-Malekshahi, M., Franssen, M., Bourajjaj, M., Weingarth, M., Ossendorp, F., Hennink, W., Amidi, M., Mastrobattista, E., & Jovanovic Ljeskovic, N. (2016). Self-assembling peptide epitopes for tumor vaccination. Arhiv za Farmaciju, 66(SPEC. ISS), 165-166.
Schiffelers, R. M., & Mastrobattista, E. (2016). Oligonucleotides. In Pharmaceutical Biotechnology: Fundamentals and Applications, Third Edition (pp. 211-224). CRC Press.
Oude Blenke, E. E., Van Den Dikkenberg, J., Van Kolck, B., Kros, A.
, & Mastrobattista, E. (2016).
Coiled coil interactions for the targeting of liposomes for nucleic acid delivery.
Nanoscale,
8(16), 8955-8965.
https://doi.org/10.1039/c6nr00711b Oude Blenke, E., Evers, M. J. W.
, Mastrobattista, E., & van der Oost, J. (Accepted/In press).
CRISPR-Cas9 gene editing: Delivery aspects and therapeutic potential.
Journal of Controlled Release.
https://doi.org/10.1016/j.jconrel.2016.08.002 Janssen, M. J., Arcolino, F. O., Schoor, P.
, Kok, R. J., & Mastrobattista, E. (2016).
Gene based therapies for kidney regeneration.
European Journal of Pharmacology,
790, 99-108.
https://doi.org/10.1016/j.ejphar.2016.07.037 Radmalekshahi, M., Lempsink, L.
, Amidi, M., Hennink, W. E., & Mastrobattista, E. (2016).
Biomedical Applications of Self-Assembling Peptides.
Bioconjugate Chemistry,
27(1), 3-18.
https://doi.org/10.1021/acs.bioconjchem.5b00487 2015
Scholarly publications
Radmalekshahi, M., Visscher, K. M.
, Garcia Lopes Maia Rodrigues, J., De Vries, R.
, Hennink, W. E., Baldus, M., Bonvin, A. M. J. J., Mastrobattista, E., & Weingarth, M. (2015).
The Supramolecular Organization of a Peptide-Based Nanocarrier at High Molecular Detail.
Journal of the American Chemical Society,
137(24), 7775-7784.
https://doi.org/10.1021/jacs.5b02919 Duinhouwer, L. E.
, Tüysüz, N., Rombouts, E. W. J. C., Ter Borg, M. N. D.
, Mastrobattista, E., Spanholtz, J., Cornelissen, J. J., Berge, D. T., & Braakman, E. (2015).
Wnt3a protein reduces growth factor-driven expansion of human hematopoietic stem and progenitor cells in serum-free cultures.
PLoS One,
10(3), [e0119086].
https://doi.org/10.1371/journal.pone.0119086Novo, L.
, Mastrobattista, E., Van Nostrum, C. F., Lammers, T., & Hennink, W. E. (2015).
Decationized polyplexes for gene delivery.
Expert Opinion on Drug Delivery,
12(4), 507-512.
https://doi.org/10.1517/17425247.2015.988136Maas, S. L. N., De Vrij, J.
, Van Der Vlist, E. J., Geragousian, B.
, Van Bloois, L., Mastrobattista, E., Schiffelers, R. M., Wauben, M. H. M., Broekman, M. L. D., & Nolte-'T Hoen, E. N. M. (2015).
Possibilities and limitations of current technologies for quantification of biological extracellular vesicles and synthetic mimics.
Journal of Controlled Release,
200, 87-96.
https://doi.org/10.1016/j.jconrel.2014.12.041Oude Blenke, E., Klaasse, G., Merten, H., Plückthun, A.
, Mastrobattista, E., & Martin, N. I. (2015).
Liposome functionalization with copper-free "click chemistry".
Journal of Controlled Release,
202, 14-20.
https://doi.org/10.1016/j.jconrel.2015.01.027 Novo, L., Takeda, K. M., Petteta, T., Dakwar, G. R.
, Van Den Dikkenberg, J. B., Remaut, K., Braeckmans, K.
, Van Nostrum, C. F., Mastrobattista, E., & Hennink, W. E. (2015).
Targeted decationized polyplexes for siRNA delivery.
Molecular Pharmaceutics,
12(1), 150-161.
https://doi.org/10.1021/mp500499x 2014
Scholarly publications
De Raad, M., Teunissen, E. A., & Mastrobattista, E. (2014).
Peptide vectors for gene delivery: From single peptides to multifunctional peptide nanocarriers.
Nanomedicine,
9(14), 2217-2232.
https://doi.org/10.2217/NNM.14.90 Rad-Malekshahi, M., Flement, M.
, Hennink, W. E., & Mastrobattista, E. (2014).
Optimization of the recombinant production and purification of a self-assembling peptide in Escherichia coli.
Microbial Cell Factories,
13(1), [178].
https://doi.org/10.1186/s12934-014-0178-0Babae, N., Bourajjaj, M., Liu, Y., Van Beijnum, J. R., Cerisoli, F., Scaria, P. V., Verheul, M., Van Berkel, M. P., Pieters, E. H. E., Van Haastert, R. J., Yousefi, A., Mastrobattista, E., Storm, G., Berezikov, E., Cuppen, E., Woodle, M., Schaapveld, R. Q. J., Prevost, G. P., Griffioen, A. W., ... Schiffelers, R. M. (2014). Systemic miRNA-7 delivery inhibits tumor angiogenesis and growth in murine xenograft glioblastoma. Oncotarget, 5(16), 6687-6700.
Lanzi, A., Fehres, C. M., De Gruijl, T. D., Van Kooyk, Y.
, & Mastrobattista, E. (2014).
Effects of antigen-expressing immunostimulatory liposomes on chemotaxis and maturation of dendritic cells in vitro and in human skin explants.
Pharmaceutical Research,
31(2), 516-526.
https://doi.org/10.1007/s11095-013-1179-0 Novo, L.
, Mastrobattista, E., Van Nostrum, C. F., & Hennink, W. E. (2014).
Targeted decationized polyplexes for cell specific gene delivery.
Bioconjugate Chemistry,
25(4), 802-812.
https://doi.org/10.1021/bc500074aYousefi, A., Lauwers, M.
, Nemes, R., van Holten, T.
, Babae, N., Roest, M., Storm, G.
, Schiffelers, R., & Mastrobattista, E. (2014).
Hemocompatibility Assessment of two siRNA Nanocarrier Formulations.
Pharmaceutical Research,
31(11), 3127-3135.
https://doi.org/10.1007/s11095-014-1405-4 Yousefi, A., Bourajjaj, M., Babae, N., Noort, P. I. V., Schaapveld, R. Q. J., Beijnum, J. R. V., Griffioen, A. W., Storm, G.
, Schiffelers, R. M., & Mastrobattista, E. (2014).
Anginex lipoplexes for delivery of anti-angiogenic siRNA.
International Journal of Pharmaceutics,
472(1-2), 175-184.
https://doi.org/10.1016/j.ijpharm.2014.06.028 Novo, L., Rizzo, L. Y., Golombek, S. K., Dakwar, G. R.
, Lou, B., Remaut, K.
, Mastrobattista, E., Van Nostrum, C. F., Jahnen-Dechent, W., Kiessling, F., Braeckmans, K.
, Lammers, T., & Hennink, W. E. (2014).
Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy.
Journal of Controlled Release,
195, 162-175.
https://doi.org/10.1016/j.jconrel.2014.08.028 2013
Scholarly publications
Schiffelers, R. M., & Mastrobattista, E. (2013).
Oligonucleotides. In
Pharmaceutical Biotechnology: Fundamentals and Applications, Fourth Edition (pp. 459-475). Springer New York LLC.
https://doi.org/10.1007/978-1-4614-6486-0_23 Teunissen, E., Mastrobattista, E., Rottier, P., & Crommelin, D. (2013).
Directed evolution of artificial viruses.
Molecular Diagnosis and Therapy,
21(9), 18-19.
https://doi.org/10.1038/mt.2013.140 Jiskoot, W., Kersten, G. F. A.
, & Mastrobattista, E. (2013).
Vaccines. In
Pharmaceutical Biotechnology: Fundamentals and Applications, Fourth Edition (pp. 439-457). Springer New York LLC.
https://doi.org/10.1007/978-1-4614-6486-0_22 de Raad, M., Kooijmans, S. A. A., Teunissen, E. A., & Mastrobattista, E. (2013).
A Solid-Phase Platform for Combinatorial and Scarless Multipart Gene Assembly.
ACS Synthetic Biology,
2(6), 316-326.
https://doi.org/10.1021/sb300122q Teunissen, E. A., de Raad, M., & Mastrobattista, E. (2013). Production and biomedical applications of virus-like particles derived from polyomaviruses. Journal of Controlled Release, 172(1), 305-21.
Mastrobattista, E. (2013). Advanced drug delivery in motion. International Journal of Pharmaceutics, 454(1), 517-20.
Yousefi, A., Storm, G., Schiffelers, R. M., & Mastrobattista, E. (2013).
Trends in polymeric delivery of nucleic acids to tumors. Journal of Controlled Release,
170(2), 209-18.
http://www.ncbi.nlm.nih.gov/pubmed/23770011 Oude Blenke, E., Mastrobattista, E., & Schiffelers, R. M. (2013).
Strategies for triggered drug release from tumor targeted liposomes. Expert Opinion on Drug Delivery,
10(10), 1399-410.
http://www.ncbi.nlm.nih.gov/pubmed/23796390 Novo, L., van Gaal, E. V. B., Mastrobattista, E., van Nostrum, C. F., & Hennink, W. E. (2013). Decationized crosslinked polyplexes for redox-triggered gene delivery. Journal of Controlled Release, 169(3), 246-56.
2012
Scholarly publications
Tuysuz, N., Van Bloois, L., Mastrobattista, E., & Ten Berge, D. (2012). Exploring the role of Wnt proteins in the regulation of hematopoietic stem cell (HSC) self-renewal and differentiation. Experimental Hematology, 40(8), 91.
Lanzi, A., Amidi, M., Fehres, C. M.
, De Raad, M., De Gruijl, T. D., Van Kooyk, Y.
, Hennink, W. E., & Mastrobattista, E. (2012).
Antigen-expressing immunostimulatory liposomes: A novel genetically-programmable vaccine platform.
Immunology,
137, 22-23.
https://doi.org/10.1111/imm.12001 Nolte - t Hoen, E. N. M., van der Vlist, E. J., Aalberts, M., Mertens, H. C. H.
, Bosch, B. J., Bartelink, W., Mastrobattista, E., van Gaal, E. V. B., Stoorvogel, W., Arkesteijn, G. J. A. A., & Wauben, M. H. M. (2012).
Quantitative and qualitative flow cytometric analysis of nanosized cell-derived membrane vesicles.
Nanomedicine : nanotechnology, biology and medicine,
8(5), 712-720.
https://doi.org/10.1016/j.nano.2011.09.006 de Raad, M., Teunissen, E. A., Lelieveld, D., Egan, D. A.
, & Mastrobattista, E. (2012).
High-content screening of peptide-based non-viral gene delivery systems.
Journal of Controlled Release,
158(3), 433-442.
http://www.ncbi.nlm.nih.gov/pubmed/21983020 de Graaf, A. J., Azevedo Próspero dos Santos, I. I., Pieters, E. H. E., Rijkers, D. T. S., van Nostrum, C. F., Vermonden, T., Kok, R. J., Hennink, W. E., & Mastrobattista, E. (2012). A micelle-shedding thermosensitive hydrogel as sustained release formulation. Journal of Controlled Release, 162, 582-590.
Joshi, M. D., Unger, W. J.
, Storm, G., van Kooyk, Y.
, & Mastrobattista, E. (2012).
Targeting tumor antigens to dendritic cells using particulate carriers. Journal of Controlled Release,
161(1), 25-37.
https://doi.org/10.1016/j.jconrel.2012.05.010 van Rooy, I., Hennink, W. E., Storm, G., Schiffelers, R. M., & Mastrobattista, E. (2012). Attaching the phage display-selected GLA peptide to liposomes: factors influencing target binding. European Journal of Pharmaceutical Sciences, 45(3), 330-5.
Mastrobattista, E., & Hennink, W. E. (2012). Polymers for gene delivery: charged for success. Nature Materials, 10-12.
Amidi, M., van Helden, M. J. G., Tabataei, N. R., de Goede, A. L., Schouten, M., de Bot, V., Lanzi, A. J. E., Gruters, R. A., Rimmelzwaan, G. F., Sijts, E. J. A. M., & Mastrobattista, E. (2012). Induction of humoral and cellular immune responses by antigen-expressing immunostimulatory liposomes. Journal of Controlled Release, 164, 323-330.
de Graaf, A. J., Mastrobattista, E., Vermonden, T., van Nostrum, C. F., Rijkers, D. T. S., Liskamp, R. M. J., & Hennink, W. E. (2012). Thermosensitive peptide-hybrid ABC block copolymers obtained by ATRP: synthesis, self assembly, and enzymatic degradation. Macromolecules, 45, 842-851.
Verheul, R. J., Hagenaars, N., van Es, T., van Gaal, E. V. B., de Jong, P. H. J. L. F., Bruijns, S., Mastrobattista, E., Slutter, B., Que, I., Heldens, J. G., van den Bosch, H., Glansbeek, H. L., Hennink, W. E., & Jiskoot, W. (2012). A step-by-step approach to study the influence of N-acetylation on the adjuvanticity of N,N,N-trimethyl chitosan (TMC) in an intranasal nanoparticulate influenza virus vaccine. European Journal of Pharmaceutical Sciences, 45(4), 467-74.
Other output
Nolte-'t Hoen, E. N. M., Wauben, M. H. M., & Mastrobattista, E. (2012). Preparation of cell-derived vesicle-inspired membrane carriers for efficient delivery of small regulatory RNAs by co-encapsulation of small infrastructural RNAs. (Patent No. 61623625).
2011
Scholarly publications
De Graaf, A. J., Mastrobattista, E., Van Nostrum, C. F., Rijkers, D. T. S., Hennink, W. E., & Vermonden, T. (2011).
ATRP, subsequent azide substitution and 'click' chemistry: Three reactions using one catalyst in one pot.
Chemical Communications,
47(24), 6972-6974.
https://doi.org/10.1039/c1cc12224j Amidi, M., de Raad, M., Crommelin, D. J. A., Hennink, W. E., & Mastrobattista, E. (2011). Antigen-expressing immunostimulatory liposomes as a genetically programmable synthetic vaccine. Syst Synth Biol, 5(1-2), 21-31.
van Rooy, I., Wu, S. Y., Storm, G., Hennink, W. E., Dinter-Heidorn, H., Schiffelers, R. M., & Mastrobattista, E. (2011). Preparation and characterization of liposomal formulations of neurotensin-degrading enzyme inhibitors. International Journal of Pharmaceutics, 416(2), 448-52.
de Graaf, A. J., Boere, K. W. M., Kemmink, J., Fokkink, R. G.
, van Nostrum, C. F., Rijkers, D. T. S., van de Gucht, J.
, Wienk, H. L. J., Baldus, M., Mastrobattista, E., Vermonden, T., & Hennink, W. E. (2011).
Looped structure of flowerlike Micelles revealed by 1H NMR relaxometry and light scattering.
Langmuir,
27(16), 9843-9848.
https://doi.org/10.1021/la2019605 van Rooy, I., Cakir-Tascioglu, S., Hennink, W. E., Storm, G., Schiffelers, R. M., & Mastrobattista, E. (2011). In vivo methods to study uptake of nanoparticles into the brain. Pharmaceutical Research, 28(3), 456-71.
van Gaal, E. V. B., van Eijk, R., Oosting, R. S., Kok, R. J., Hennink, W. E., Crommelin, D. J. A., & Mastrobattista, E. (2011). How to screen non-viral gene delivery systems in vitro? Journal of Controlled Release, 154(3), 218-32.
van Gaal, E. V. B., Oosting, R. S., van Eijk, R., Bakowska, M., Feyen, D., Kok, R. J., Hennink, W. E., Crommelin, D. J. A., & Mastrobattista, E. (2011). DNA nuclear targeting sequences for non-viral gene delivery. Pharmaceutical Research, 28(7), 1707-22.
van Rooy, I., Mastrobattista, E., Storm, G., Hennink, W. E., & Schiffelers, R. M. (2011). Comparison of five different targeting ligands to enhance accumulation of liposomes into the brain. Journal of Controlled Release, 150, 30-36.
de Graaf, A. J., Mastrobattista, E., van Nostrum, C. F., Rijkers, D. T. S., Hennink, W. E., & Vermonden, T. (2011). ATRP, subsequent azide substitution and "click" chemistry: three reactions using one catalyst in a one-pot. Chemical Communications, 47, 6972-6974.
Other output
van Rooy, I., Hennink, W. E., Mastrobattista, E., Schiffelers, R. M., Dinther-Heidorn, H., Brinkhuis, R. P., van Hest, J., & Rutjes, F. (2011). Peptide ligands for targeting to the blood-brain barrier. (Patent No. WO/2011/005098).
2010
Scholarly publications
Hagenaars, N., Mastrobattista, E., & Jiskoot, W. (2010). Trimethylchitosan vergroot effectiviteit door beter contact: Op weg naar een intran asaal griepvaccin. Pharmaceutisch Weekblad, 145(42), 16-19.
van Rooy, I., Cakir-Tascioglu, S., Couraud, P. O., Romero, I. A., Weksler, B., Storm, G., Hennink, W. E., Schiffelers, R. M., & Mastrobattista, E. (2010). Identification of peptide ligands for targeting to the blood-brain barrier. Pharmaceutical Research, 27(4), 673-82.
Amidi, M., de Raad, M., de Graauw, H., van Ditmarsch, D., Hennink, W. E., Crommelin, D. J. A., & Mastrobattista, E. (2010). Optimization and quantification of protein synthesis inside liposomes. Journal of Liposome Research, 20(1), 73-83.
van Hell, A. J., Fretz, M. M., Crommelin, D. J. A., Hennink, W. E., & Mastrobattista, E. (2010). Peptide nanocarriers for intracellular delivery of photosensitizers. Journal of Controlled Release, 141(3), 347-53.
van Hell, A. J., Klymchenko, A.
, Burgers, P. P., Moret, E. E., Jiskoot, W., Hennink, W. E., Crommelin, D. J. A., & Mastrobattista, E. (2010).
Conformation and intermolecular interactions of SA2 peptides self-assembled into vesicles. Journal of Physical Chemistry. B,
114(34), 11046-52.
https://dspace.library.uu.nl/bitstream/handle/1874/258658/jp103440d.pdf?sequence=1 Amidi, M., Mastrobattista, E., Jiskoot, W., & Hennink, W. E. (2010). Chitosan-based delivery systems for protein therapeutics and antigens. Advanced Drug Delivery Reviews, 62(1), 59-82.
Hagenaars, N., Mania, M. M., de Jong, P., Que, I., Nieuwland, R., Slutter, B., Glansbeek, H. L., Heldens, J., van den Bosch, H., Lowik, C., Kaijzel, E. L., Mastrobattista, E., & Jiskoot, W. (2010). Role of trimethylated chitosan (TMC) in nasal residence time, local distribution and toxicity of an intranasal influenza vaccine. Journal of Controlled Release, 144, 17-24.
van Gaal, E. V. B., Oosting, R. S., Hennink, W. E., Crommelin, D. J. A., & Mastrobattista, E. (2010). Junk DNA enhances pEI-based non-viral gene delivery. International Journal of Pharmaceutics, 390(1), 76-83.
van Gaal, E. V. B., Spierenburg, G., Hennink, W. E., Crommelin, D. J. A., & Mastrobattista, E. (2010). Flow cytometry for rapid size determination and sorting of nucleic acid containing nanoparticles in biological fluids. Journal of Controlled Release, 141(3), 328-38.
Other output
Nolte-'t Hoen, E. N. M., van der Vlist, E. J., Mertens, H. C. H., Mastrobattista, E., van Gaal, E. V. B., Bosch, B. J., Stoorvogel, W., Arkesteijn, G., & Wauben, M. H. M. (2010). Flow cytometric analysis of individual biological nanoparticles. Abstract from 9th International Conference on New Trends in Immunosuppression and Immunotherapy 2010, Geneva, Switzerland.
2009
Scholarly publications
Hagenaars, N., Mastrobattista, E., Verheul, R. J., Mooren, I., Glansbeek, H. L., Heldens, J. G. M., van den Bosch, H., & Jiskoot, W. (2009). Physicochemical and Immunological Characterization of N,N,N-Trimethyl Chitosan-Coated Whole Inactivated Influenza Virus Vaccine for Intranasal Administration. Pharmaceutical Research, 26(6), 1353-1364.
Hagenaars, N., Verheul, R. J., Mooren, I., de Jong, P. H. J. L. F., Mastrobattista, E., Glansbeek, H. L., Heldens, J. G., van den Bosch, H., Hennink, W. E., & Jiskoot, W. (2009). Relationship between structure and adjuvanticity of N,N,N-trimethyl chitosan (TMC) structural variants in a nasal influenza vaccine. Journal of Controlled Release, 140(2), 126-33.
Wilschut, K. J., van der Aa, M., Oosting, R. S., Hennink, W. E., Koning, G. A., Crommelin, D. J. A., & Mastrobattista, E. (2009). Fluorescence in situ hybridization to monitor the intracellular location and accessibility of plasmid DNA delivered by cationic polymer-based gene carriers. European Journal of Pharmaceutics and Biopharmaceutics, 72(2), 391-396.
de Graaf, A. J., Kooijman, M., Hennink, W. E., & Mastrobattista, E. (2009). Nonnatural Amino Acids for Site-Specific Protein Conjugation. Bioconjugate Chemistry, 20(7), 1281-1295.
van Hell, A. J., Crommelin, D. J., Hennink, W. E., & Mastrobattista, E. (2009). Stabilization of peptide vesicles by introducing inter-peptide disulfide bonds. Pharmaceutical Research, 26(9), 2186-93.
Other output
Hennink, W. E., Amidi, M., & Mastrobattista, E. (2009). Antigen-expressing liposomes.
2008
Scholarly publications
Fens, M. H. A. M., Mastrobattista, E., De Graaff, A. M., Flesch, F. M., Ultee, A., Rasmussen, J. T., Molema, G.
, Storm, G., & Schiffelers, R. M. (2008).
Angiogenic endothelium shows lactadherin-dependent phagocytosis of aged erythrocytes and apoptotic cells.
Blood,
111(9), 4542-4550.
https://doi.org/10.1182/blood-2007-06-094763 de Wolf, H. K., Johansson, N., Thong, A. T.
, Snel, C. J., Mastrobattista, E., Hennink, W. E., & Storm, G. (2008).
Plasmid CpG depletion improves degree and duration of tumor gene expression after intravenous administration of polyplexes.
Pharmaceutical Research,
25, 1654-1662.
https://dspace.library.uu.nl/bitstream/handle/1874/41760/2008_31.pdf?sequence=1 Fens, M. H. A. M., Mastrobattista, E., de Graaff, A. M., Flesch, F. M., Ultee, A., Rasmussen, J., Molema, G.
, Storm, G., & Schiffelers, R. M. (2008).
Angiogenic dndothelium shows lactadherin-dependent phagocytosis of aged erythrocytes and apoptotic cells. Blood,
111(9), 4542-4550.
https://dspace.library.uu.nl/bitstream/handle/1874/37414/2008%252329.pdf?sequence=1 Hagenaars, N., Mastrobattista, E., Glansbeek, H. L., Helden, J., van den Bosch, H., Schijns, V., Betbeder, D., Vromans, H., & Jiskoot, W. (2008). Head-to-head comparison of four nonadjuvanted inactivated cell culture-derived influenza vaccines: Effect of composition, spatial organization and immunization route on the immunogenicity in a murine challenge model. Vaccine, 51, 6555-6563.
2007
Scholarly publications
Mastrobattista, E., Hennink, W. E., & Schiffelers, R. M. (2007). Delivery of nucleic acids. Pharmaceutical Research, 24, 1561-1563.
van der Aa, M. A. E. M., Huth, U. S., Häfele, S. Y., Schubert, R.
, Oosting, R. S., Mastrobattista, E., Hennink, W. E., Peschka-Süss, R., Koning, G. A.
, & Crommelin, D. J. A. (2007).
Cellular uptake of cationic polymer-DNA complexes via caveolae plays a pivotal role in gene transfection in COS-7 cells.
Pharmaceutical Research,
24, 1590-1598.
https://dspace.library.uu.nl/bitstream/handle/1874/31094/Cellular%2520uptake.pdf?sequence=1van Hell, A. J., Costa, C. I. C. A., Flesch, F. M., Sutter, M., Jiskoot, W., Crommelin, D. J. A., Hennink, W. E., & Mastrobattista, E. (2007). Self-assembly of recombinant amphiphilic oligopeptides into vesicles. Biomacromolecules, 8, 2753-2761.
Professional publications
Jiskoot, W., Kersten, G. F. A., & Mastrobattista, E. (2007). Vaccines. In D. J. A. Crommelin, R. D. Sindelar, & B. Meibohm (Eds.), Pharmaceutical Biotechnology, An Introduction for Pharmacists and Pharmaceutical Scientists (pp. 405-427). Informa Healthcare.
Schiffelers, R. M., & Mastrobattista, E. (2007). Oligonucleotides. In D. J. A. Crommelin, R. D. Sindelar, & B. Meibohm (Eds.), Pharmaceutical Biotechnology, An Introduction for Pharmacists and Pharmaceutical Scientists (pp. 211-223). Informa Healthcare.
2006
Scholarly publications
Miller, O. J., Bernath, K., Agresti, J. J., Amitai, G., Kelly, B. T.
, Mastrobattista, E., Taly, V., Magdassi, S., Tawfik, D. S., & Griffiths, A. D. (2006).
Directed evolution by in vitro compartmentalization.
Nature Methods,
3(7), 561-570.
https://doi.org/10.1038/nmeth897Koning, G. A.
, Schiffelers, R. M., Wauben, M. H. M., Kok, R. J., Mastrobattista, E., Molema, G., Ten Hagen, T. L. M.
, & Storm, G. (2006).
Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate-containing RGD peptide liposomes inhibits experimental arthritis.
Arthritis and Rheumatism,
54(4), 1198-1208.
https://doi.org/10.1002/art.21719Miller, O. J., Bernath, K., Agresti, J. J., Amitai, G., Kelly, B. T., Mastrobattista, E., Taly, V., Magdassi, S., Tawfik, D. S., & Griffiths, A. D. (2006). Direct evolution by in vitro compartmentalization. Nature Methods, 3, 561-570.
van der Aa, M. A. E. M.
, Mastrobattista, E., Oosting, R. S., Hennink, W. E., Koning, G. A.
, & Crommelin, D. J. A. (2006).
The nuclear pore complex: the gateway to successful nonviral gene delivery.
Pharmaceutical Research,
23(3), 447-459.
https://dspace.library.uu.nl/bitstream/handle/1874/19728/oosting_06_nuclearporecomplex.pdf?sequence=2Mastrobattista, E., van der Aa, M. A. E. M., Hennink, W. E., & Crommelin, D. J. A. (2006). Artificial viruses: a nanotechnological approach to gene delivery. Nature Reviews. Drug Discovery, 5, 115-121.
van Gaal, E. V. B., Hennink, W. E., Crommelin, D. J. A., & Mastrobattista, E. (2006). Plasmid engineering for controlled and sustained gene expression for nonviral gene therapy. Pharmaceutical Research, 23, 1053-1074.
2005
Scholarly publications
Mastrobattista, E., Bravo, S. A., van der Aa, M.
, & Crommelin, D. J. A. (2005).
Nonviral gene delivery systems: From simple transfection agents to artificial viruses.
Drug Discovery Today: Technologies,
2(1), 103-109.
https://doi.org/10.1016/j.ddtec.2005.04.002 Mastrobattista, E., Taly, V., Chanudet, E., Treacy, P., Kelly, B. T., & Griffiths, A. D. (2005).
High-throughput screening of enzyme libraries: In vitro evolution of a β-galactosidase by fluorescence-activated sorting of double emulsions.
Chemistry and Biology,
12(12), 1291-1300.
https://doi.org/10.1016/j.chembiol.2005.09.016 Mastrobattista, E., Bravo, S. A., van der Aa, M. A. E. M., & Crommelin, D. J. A. (2005). Nonviral gene delivery systems: from simple transfection agents to artifical viruses. Drug Discovery Today. Technologies, 2, 103-109.
Mastrobattista, E., Taly, V., Chanudet, E., Treacy, P., Kelly, B. T., & Griffiths, A. D. (2005). High-throughput screening of enzyme libraries: in vitro evolution of a b-galactosidase by fluorescence-activated sorting of double emulsiom. Chemistry & Biology, 12, 1291-1300.
Fretz, M. M., Mastrobattista, E., Koning, G. A., Jiskoot, W., & Storm, G. (2005). Strategies for cytosolic delivery of liposomal macromolecules. International Journal of Pharmaceutics, 298(2), 305-309.
2004
Scholarly publications
Bernath, K., Hai, M.
, Mastrobattista, E., Griffiths, A. D., Magdassi, S., & Tawfik, D. S. (2004).
In vitro compartmentalization by double emulsions: Sorting and gene enrichment by fluorescence activated cell sorting.
Analytical Biochemistry,
325(1), 151-157.
https://doi.org/10.1016/j.ab.2003.10.005Fretz, M. M., Koning, G. A.
, Mastrobattista, E., Jiskoot, W., & Storm, G. (2004).
OVCAR-3 cells internalize TAT-peptide modified liposomes by endocytosis.
Biochimica et Biophysica Acta - Biomembranes,
1665(1-2), 48-56.
https://doi.org/10.1016/j.bbamem.2004.06.022 Fretz, M. M., Koning, G. A., Mastrobattista, E., Jiskoot, W., & Storm, G. (2004). Ovcar-3 cells internalise TAT-peptide modified lipsomoes by endocytosis. Biochimica et Biophysica Acta-Biomembranes, 1665, 48-56.
2003
Scholarly publications
Crommelin, D. J. A., Storm, G., Jiskoot, W., Stenekes, R. J. H., Mastrobattista, E., & Hennink, W. E. (2003). Nanotechnological approaches for the delivery of macromolecules. Journal of Controlled Release, 87, 81-88.
2002
Scholarly publications
Metselaar, J. M., Mastrobattista, E., & Storm, G. (2002). Liposomes for intravenous drug targeting: design and applications. Mini-Reviews in Medicinal Chemistry, 2, 319-329.
Mastrobattista, E., Crommelin, D. J. A., Wilschut, J., & Storm, G. (2002). Targeted liposomes for delivery of protein-based drugs into the cytoplasm of tumor cells. Journal of Liposome Research, 12, 57-65.
Mastrobattista, E., Koning, G. A., van Bloois, L., Filipe, A. C. S., Jiskoot, W., & Storm, G. (2002). Functional characterization of an endosome-disruptive peptide and its application in cytosolic delivery of immunoliposome-entrapped proteins. Journal of Biological Chemistry, 277, 27135-27143.
2001
Scholarly publications
Mastrobattista, E., Schoen, P., Wilschut, J.
, Crommelin, D. J. A., & Storm, G. (2001).
Targeting influenza virosomes to ovarian carcinoma cells.
FEBS Letters,
509(1), 71-76.
https://doi.org/10.1016/S0014-5793(01)03112-X Mastrobattista, E., Schoen, P., Wilschut, J., Crommelin, D. J. A., & Storm, G. (2001). Targeting influenza vitrosomes to ovarian carcinoma cells. FEBS Letters, 509, 71-76.
Storm, G., Mastrobattista, E., Verbaan, F. J., Crommelin, D. J. A., & Hennink, W. E. (2001). Design of methacrylate-based polyplexes for tumor targeting. Gene Therapy, 6, 143-148.
Mastrobattista, E., Kapel, R. H. G., Eggenhuisen, M. H., Roholl, P. J. M., Crommelin, D. J. A., Hennink, W. E., & Storm, G. (2001). Lipid-coated polyplexes for targeted gene delivery to ovarian carcinoma cells. Cancer Gene Therapy, 8, 405-413.
Mastrobattista, E. (2001). Targeted liposomes for cytosolic drug delivery to tumor cells.
1999
Scholarly publications
Mastrobattista, E., Storm, G., van Bloois, L., Reszka, R., Bloemen, P. G. M., Crommelin, D. J. A., & Henricks, P. A. J. (1999). Cellular uptake of liposomes targeted to intercellular adhesion molecule-1 (ICAM-1) on bronchial epithelial cells. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1419, 353-363.
Mastrobattista, E., Koning, G. A., & Storm, G. (1999). Immunoliposomes for the targeted deliverey of antitumor drugs. Advanced Drug Delivery Reviews, 40, 103-127.