Dr. E.J.M. (Marijke) Achterberg

Dr. E.J.M. (Marijke) Achterberg

Assistant Professor
Animals in Science & Society
+31 30 253 4570
e.j.m.achterberg@uu.nl

Publications

2024

Scholarly publications

Achterberg, M., Lozeman - van t Klooster, J., Pimentel, T., Aleksic, A., Hendriks, J., Nijhof, S. L., Van Der Ent, C. K., & Lesscher, H. (2024). Effect of social play deprivation on stress sensitivity in response to social and non-social challenges. Frontiers in Ethology: Behavioral Development and Play, 3(1458136), 1-11. https://doi.org/10.3389/fetho.2024.1458136
Nyberg, H., Bogen, I. L., Nygaard, E., Achterberg, M., & Andersen, J. M. (2024). Maternal exposure to buprenorphine, but not methadone, during pregnancy reduces social play behavior across two generations of offspring. Psychopharmacology. Advance online publication. https://doi.org/10.1007/s00213-024-06718-2
Brandt, M. J. V., Kosmeijer, C. M., Achterberg, E. J. M., de Theije, C. G. M., & Nijboer, C. H. (2024). Timed fetal inflammation and postnatal hypoxia cause cortical white matter injury, interneuron imbalances, and behavioral deficits in a double-hit rat model of encephalopathy of prematurity. Brain, Behavior, and Immunity - Health, 40, Article 100817. https://doi.org/10.1016/j.bbih.2024.100817
https://research-portal.uu.nl/ws/files/235532483/1-s2.0-S2666354624000954-main.pdf
Hermans, E. C., de Theije, C. G. M., Nijboer, C. H. A., & Achterberg, E. J. M. (2024). Ultrasonic vocalization emission is altered following neonatal hypoxic-ischemic brain injury in mice. Behavioural Brain Research, 471, Article 115113. https://doi.org/10.1016/j.bbr.2024.115113
https://research-portal.uu.nl/ws/files/229034078/1-s2.0-S0166432824002699-main.pdf
Bijlsma, A., Birza, E., Pimentel, T., Maranus, J., van Gaans, M., Lozeman - van t Klooster, J., Baars, A.-M., Achterberg, M., Lesscher, H., Wierenga, C., & Vanderschuren, L. (2024). Opportunities for risk-taking during play alters cognitive performance and prefrontal inhibitory signalling in rats of both sexes. European Journal of Neuroscience, 59(10), 2748-2765. https://doi.org/10.1111/ejn.16313
https://dspace.library.uu.nl/bitstream/handle/1874/452399/Eur_J_of_Neuroscience_-_2024_-_Bijlsma_-_Opportunities_for_risk_taking_during_play_alters_cognitive_performance_and.pdf?sequence=1
Achterberg, M., Biemans, B., & Vanderschuren, L. (2024). Neurexin1α knockout in rats causes aberrant social behaviour: relevance for autism and schizophrenia. Psychopharmacology. Advance online publication. https://doi.org/10.1007/s00213-024-06559-z

2023

Scholarly publications

Achterberg, E. J. M., Burke, C. J., & Pellis, S. M. (2023). When the individual comes into play: The role of self and the partner in the dyadic play fighting of rats. Behavioural Processes, 212, 1-12. Article 104933. https://doi.org/10.1016/j.beproc.2023.104933
https://dspace.library.uu.nl/bitstream/handle/1874/430938/1-s2.0-S0376635723001158-main.pdf?sequence=1
Achterberg, E. J. M., & Vanderschuren, L. J. M. J. (2023). The neurobiology of social play behaviour: Past, present and future. Neuroscience and Biobehavioral Reviews, 152, Article 105319. https://doi.org/10.1016/j.neubiorev.2023.105319
https://dspace.library.uu.nl/bitstream/handle/1874/429703/1-s2.0-S0149763423002889-main.pdf?sequence=1

2022

Scholarly publications

Pellis, S., Pellis, V., Ham, J., & Achterberg, M. (2022). The rough-and-tumble play of rats as a natural behavior suitable for studying the social brain. Frontiers in Behavioral Neuroscience, 16, 1-5. Article 1033999. https://doi.org/10.3389/fnbeh.2022.1033999
https://dspace.library.uu.nl/bitstream/handle/1874/423444/fnbeh_16_1033999.pdf?sequence=1
Burke, C., Pellis, S., & Achterberg, M. (2022). Who's laughing? Play, tickling and ultrasonic vocalizations in rats. Philosophical Transactions of the Royal Society B: Biological Sciences, 377(1863), 1-9. Article 20210184. https://doi.org/10.1098/rstb.2021.0184
https://dspace.library.uu.nl/bitstream/handle/1874/422894/s12888_022_04098_5.pdf?sequence=1
Achterberg, E. J. M., van Oldeniel, R. J., van Tilborg, E., Verharen, J. P. H., Nijboer, C. H., & Vanderschuren, L. J. M. J. (2022). Cognitive performance during adulthood in a rat model of neonatal diffuse white matter injury. Psychopharmacology, 239(3), 745-764. https://doi.org/10.1007/s00213-021-06053-w
https://dspace.library.uu.nl/bitstream/handle/1874/419206/Achterberg2022_Article_CognitivePerformanceDuringAdul.pdf?sequence=1
Pellis, S., Pellis, V., Burke, C., Stark, R., Ham, J., Euston, D., & Achterberg, M. (2022). Measuring play fighting in rats: A multilayered approach. Current Protocols, 2(1), 1-28. Article e337. https://doi.org/10.1002/cpz1.337

2021

Scholarly publications

Achterberg, M., & Baars, A. (2021). Een kijkje in het brein van spelende ratten. Abstract from Biotechnische dagen 2021.
Pimentel, T., Achterberg, M., Lozeman - van t Klooster, J., Baars, A., Kirchhoff, S., Vanderschuren, L., & Lesscher, H. (2021). Don’t stress play time! On the interaction of social play and glucocorticoids. Poster session presented at Dutch Neuroscience Meeting.
https://research-portal.uu.nl/ws/files/112557126/Poster_Glucocorticoids_Social_Play_Tara.pdf
Burke, C., Pellis, S., Vanderschuren, L., & Achterberg, M. (2021). Individual differences in social play behaviour in rats: behavioural microstructure and communication. In Dutch Neuroscience Meeting 2021
Burke, C., Pellis, S., Vanderschuren, L., & Achterberg, M. (2021). Individual differences in social play behaviour in rats: behavioural microstructure and communication. In EBPS 2021
Burke, C., Pellis, S., Vanderschuren, L., & Achterberg, M. (2021). Individual differences in social play behaviour in rats: behavioural microstructure and communication. In Global Connectome 2021
Vanderschuren, L., & Achterberg, M. (2021). Social Play Behavior. In S. Della Sala (Ed.), Encyclopedia of Behavioral Neuroscience (2 ed., pp. 85-92). Elsevier. https://doi.org/10.1016/B978-0-12-819641-0.00021-9
Lesscher, H. M. B., Achterberg, E. J. M., Siviy, S. M., & Vanderschuren, L. J. M. J. (2021). Individual differences in social play behaviour predict alcohol intake and control over alcohol seeking in rats. Psychopharmacology, 238(11), 3119-3130. https://doi.org/10.1007/s00213-021-05929-1
https://dspace.library.uu.nl/bitstream/handle/1874/412693/Lesscher2021_Article_IndividualDifferencesInSocialP.pdf?sequence=1

2020

Scholarly publications

Vanderschuren, L. J. M. J., & Achterberg, E. J. M. (2020). Social Play Behavior. In Reference Module in Neuroscience and Biobehavioral Psychology (Elsevier Reference Collection in Neuroscience and Biobehavioral Psychology). Elsevier. https://doi.org/10.1016/b978-0-12-819641-0.00021-9
Achterberg, E. J. M., & Vanderschuren, L. J. M. J. (2020). Treatment with low doses of nicotine but not alcohol affects social play reward in rats. International Journal of Play, 9, 39-57. https://doi.org/10.1080/21594937.2020.1720121
https://dspace.library.uu.nl/bitstream/handle/1874/408000/Treatment_with_low_doses_of_nicotine_but_not_alcohol_affects_social_play_reward_in_rats.pdf?sequence=1

2019

Scholarly publications

Menon, J. M. L., Nolten, C., Achterberg, E. J. M., Joosten, R. N. J. M. A., Dematteis, M., Feenstra, M. G. P., Drinkenburg, W. H., & Leenaars, C. H. C. (2019). Brain Microdialysate Monoamines in Relation to Circadian Rhythms, Sleep, and Sleep Deprivation – a Systematic Review, Network Meta-analysis, and New Primary Data. Journal of Circadian Rhythms, 17(1), 1-32. Article 1. https://doi.org/10.5334/jcr.174
https://dspace.library.uu.nl/bitstream/handle/1874/377905/174_1634_2_PB.pdf?sequence=1
Achterberg, E. J. M., van Swieten, M. M. H., Houwing, D. J., Trezza, V., & Vanderschuren, L. J. M. J. (2019). Opioid modulation of social play reward in juvenile rats. Neuropharmacology, 159, Article 107332. https://doi.org/10.1016/j.neuropharm.2018.09.007
https://dspace.library.uu.nl/bitstream/handle/1874/389736/1_s2.0_S0028390818306324_main.pdf?sequence=1

2018

Scholarly publications

Nijhof, S. L., Vinkers, C. H., van Geelen, S. M., Duijff, S. N., Achterberg, E. J. M., der Net, J. V., Veltkamp, R. C., Grootenhuis, M. A., de Putte, E. M. V., Hillegers, M. H. J., der Brug, A. W. V., Wierenga, C. J., Benders, M. J. N. L., Engels, R. C. M. E., der Ent, C. K. V., Vanderschuren, L. J. M. J., & Lesscher, H. M. B. (2018). Healthy play, better coping: The importance of play for the development of children in health and disease. Neuroscience and Biobehavioral Reviews, 95, 421-429. https://doi.org/10.1016/j.neubiorev.2018.09.024
https://dspace.library.uu.nl/bitstream/handle/1874/372326/Healthy.pdf?sequence=1
Kentrop, J., Smid, C., Achterberg, E. J. M., van Ijzerdoorn, M., Bakermans-Kranenburg, M., Joels, M., & van der Veen, R. (2018). Effects of Maternal Deprivation and Complex Housing on Rat Social Behavior in Adolescence and Adulthood. Frontiers in Behavioral Neuroscience, 12, 1-15. Article 193. https://doi.org/10.3389/fnbeh.2018.00193
https://dspace.library.uu.nl/bitstream/handle/1874/371953/kentrop.pdf?sequence=1
Achterberg, E. J. M., Damsteegt, R., & Vanderschuren, L. J. M. J. (2018). On the central noradrenergic mechanism underlying the social play-suppressant effect of methylphenidate in rats. Behavioural Brain Research, 347, 158-166. https://doi.org/10.1016/j.bbr.2018.03.004
https://dspace.library.uu.nl/bitstream/handle/1874/362876/achterberg.pdf?sequence=1
van Tilborg, E., Achterberg, E. J. M., van Kammen, C. M., van der Toorn, A., Groenendaal, F., Dijkhuizen, R. M., Heijnen, C. J., Vanderschuren, L. J. M. J., Benders, M. N. J. L., & Nijboer, C. H. A. (2018). Combined fetal inflammation and postnatal hypoxia causes myelin deficits and autism-like behavior in a rat model of diffuse white matter injury. GLIA, 66(1), 78-93. https://doi.org/10.1002/glia.23216
https://dspace.library.uu.nl/bitstream/handle/1874/358494/5.pdf?sequence=1

2016

Scholarly publications

Vanderschuren, L. J. M. J., Achterberg, E. J. M., & Trezza, V. (2016). The neurobiology of social play and its rewarding value in rats. Neuroscience and Biobehavioral Reviews, 70, 86-105. https://doi.org/10.1016/j.neubiorev.2016.07.025
https://dspace.library.uu.nl/bitstream/handle/1874/347918/neurobiology.pdf?sequence=1
Achterberg, E. J. M., van Swieten, M. M. H., Driel, N. V., Trezza, V., & Vanderschuren, L. J. M. J. (2016). Dissociating the role of endocannabinoids in the pleasurable and motivational properties of social play behaviour in rats. Pharmacological Research, 110, 151-158. https://doi.org/10.1016/j.phrs.2016.04.031
https://dspace.library.uu.nl/bitstream/handle/1874/347916/Dissociating.pdf?sequence=1
Achterberg, E. J. M., van Kerkhof, L. W. M., Servadio, M., van Swieten, M., Houwing, D. J., Aalderink, M., Driel, N. V., Trezza, V., & Vanderschuren, L. J. M. J. (2016). Contrasting Roles of Dopamine and Noradrenaline in the Motivational Properties of Social Play Behavior in Rats. Neuropsychopharmacology, 41(3), 858-868. https://doi.org/10.1038/npp.2015.212
https://dspace.library.uu.nl/bitstream/handle/1874/329701/contrasting.pdf?sequence=1

2015

Scholarly publications

Achterberg, M., Van Kerkhof, L. W. M., Servadio, M., Van Swieten, M. M. H., Houwing, D. H., Aalderink, M., Trezza, V., & Vanderschuren, L. J. M. J. (2015). Measuring motivation and performance of social play behavior in rats: Role of dopamine and noradrenaline. European Neuropsychopharmacology, 25(pp S29-S30), March. https://doi.org/10.1016/S0924-977X(15)30007-9
https://dspace.library.uu.nl/bitstream/handle/1874/380175/s2.0_S0924977X15300079.pdf?sequence=1
Achterberg, E. J. M., van Kerkhof, L. W. M., Damsteegt, R., Trezza, V., & Vanderschuren, L. J. M. J. (2015). Methylphenidate and atomoxetine inhibit social play behavior through prefrontal and subcortical limbic mechanisms in rats. Journal of Neuroscience, 35(1), 161-169. https://doi.org/10.1523/JNEUROSCI.2945-14.2015
https://dspace.library.uu.nl/bitstream/handle/1874/326550/161.full.pdf?sequence=1

2014

Scholarly publications

Achterberg, E. J. M., Trezza, V., Siviy, S. M., Schrama, L. H., Schoffelmeer, A. N., & Vanderschuren, L. J. M. J. (2014). Amphetamine and cocaine suppress social play behavior in rats through distinct mechanisms. Psychopharmacology, 231(8), 1503-1515. https://doi.org/10.1007/s00213-013-3272-9
https://dspace.library.uu.nl/bitstream/handle/1874/314221/rats.pdf?sequence=1
Achterberg, E. J. M. (2014). On the pleasurable, motivational and cognitive aspects of social play behavior: pharmacological studies in rats. [Doctoral thesis 1 (Research UU / Graduation UU), Utrecht University]. Brain Center Rudolf Magnus, Universiteit Utrecht.
https://dspace.library.uu.nl/bitstream/handle/1874/291368/achterberg.pdf?sequence=1
Achterberg, E. J. M., Trezza, V., & Vanderschuren, L. J. M. J. (2014). Glucocorticoid receptor antagonism disrupts the reconsolidation of social reward-related memories in rats. Behavioural Pharmacology, 25(3), 216-225. https://doi.org/10.1097/FBP.0000000000000039
https://dspace.library.uu.nl/bitstream/handle/1874/386212/Glucocorticoid_receptor_antagonism.pdf?sequence=1

2012

Scholarly publications

Achterberg, E. J. M., Trezza, V., & Vanderschuren, L. J. M. J. (2012). β-Adrenoreceptor stimulation mediates reconsolidation of social reward-related memories. PLoS One, 7, e39639. Article e39639. https://doi.org/10.1371/journal.pone.0039639
https://dspace.library.uu.nl/bitstream/handle/1874/386234/Social_Reward_Related_Memories.PDF?sequence=1
Vanderschuren, L. J. M. J., Achterberg, E. J. M., Baarendse, P. J. J., Damsteegt, R., van Kerkhof, L. W. M., & Trezza, V. (2012). Studying the neurobehavioral mechanisms of social behavior in adolescent rats. In A. J. Spink, F. Grieco, O. E. Krips, L. W. S. Loijens, L. P. J. J. Noldus, & P. H. Zimmerman (Eds.), Proceedings of Measuring Behavior 2012 (pp. 135-137)
https://dspace.library.uu.nl/bitstream/handle/1874/386201/Measuring_Behavior_2012.pdf?sequence=1

2011

Scholarly publications

Trezza, V., Damsteegt, R., Achterberg, E. J. M., & Vanderschuren, L. J. M. J. (2011). Nucleus Accumbens Mu-Opioid Receptors Mediate Social Reward. Journal of Neuroscience, 31(17), 6362-6370. https://doi.org/10.1523/JNEUROSCI.5492-10.2011
https://dspace.library.uu.nl/bitstream/handle/1874/236401/Neuroscience%252027-4-11.pdf?sequence=1