Publications
2022
Scholarly publications
Noordstra, I., van den Berg, C. M., Boot, F. W. J., Katrukha, E. A., Yu, K. L., Tas, R. P., Portegies, S., Viergever, B. J., de Graaff, E., Hoogenraad, C. C., de Koning, E. J. P., Carlotti, F., Kapitein, L. C., & Akhmanova, A. (2022). Organization and dynamics of the cortical complexes controlling insulin secretion in β-cells. Journal of Cell Science, 135(3), 1-18. [jcs259430]. https://doi.org/10.1242/jcs.259430
2021
Scholarly publications
Lindhout, F. W., Portegies, S., Kooistra, R., Herstel, L. J., Stucchi, R., Hummel, J. J. A., Scheefhals, N., Katrukha, E. A., Altelaar, M., MacGillavry, H. D., Wierenga, C. J., & Hoogenraad, C. C. (2021). Centrosome-mediated microtubule remodeling during axon formation in human iPSC-derived neurons. EMBO Journal, 40(10), 1-17. [e106798]. https://doi.org/10.15252/embj.2020106798
Buijs, R. R., Hummel, J. J. A., Burute, M., Pan, X., Cao, Y., Stucchi, R., Altelaar, M., Akhmanova, A., Kapitein, L. C., & Hoogenraad, C. C. (2021). WDR47 protects neuronal microtubule minus ends from katanin-mediated severing. Cell Reports, 36(2), 1-e7. [109371]. https://doi.org/10.1016/j.celrep.2021.109371
Özkan, N., Koppers, M., van Soest, I., van Harten, A., Jurriens, D., Liv, N., Klumperman, J., Kapitein, L. C., Hoogenraad, C. C., & Farías, G. G. (2021). ER - lysosome contacts at a pre-axonal region regulate axonal lysosome availability. Nature Communications, 12(1), [4493]. https://doi.org/10.1038/s41467-021-24713-5
Zahavi, E. E., Hummel, J. J. A., Han, Y., Bar, C., Stucchi, R., Altelaar, M., & Hoogenraad, C. C. (2021). Combined kinesin-1 and kinesin-3 activity drives axonal trafficking of TrkB receptors in Rab6 carriers. Developmental Cell, 56(4), 494-508.E7. https://doi.org/10.1016/j.devcel.2021.01.010
2020
Scholarly publications
van Gelder, C. A. G. H., Penning, R., Veth, T. S., Catsburg, L. A. E., Hoogenraad, C. C., MacGillavry, H. D., & Altelaar, M. (2020). Temporal Quantitative Proteomics of mGluR-induced Protein Translation and Phosphorylation in Neurons. Molecular and Cellular Proteomics, 19(12), 1952-1967. https://doi.org/10.1074/mcp.RA120.002199
Vogl, A. M., Phu, L., Becerra, R., Giusti, S. A., Verschueren, E., Hinkle, T. B., Bordenave, M. D., Adrian, M., Heidersbach, A., Yankilevich, P., Stefani, F. D., Wurst, W., Hoogenraad, C. C., Kirkpatrick, D. S., Refojo, D., & Sheng, M. (2020). Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics. Nature Structural and Molecular Biology, 27(2), 210-220. https://doi.org/10.1038/s41594-019-0370-3
Rossor, A. M., Sleigh, J. N., Groves, M., Muntoni, F., Reilly, M. M., Hoogenraad, C. C., & Schiavo, G. (2020). Loss of BICD2 in muscle drives motor neuron loss in a developmental form of spinal muscular atrophy. Acta neuropathologica communications, 8(1), [34]. https://doi.org/10.1186/s40478-020-00909-6
Abouelezz, A., Stefen, H., Segerstråle, M., Micinski, D., Minkeviciene, R., Lahti, L., Hardeman, E. C., Gunning, P. W., Hoogenraad, C. C., Taira, T., Fath, T., & Hotulainen, P. (2020). Tropomyosin Tpm3.1 Is Required to Maintain the Structure and Function of the Axon Initial Segment. iScience, 23(5), [101053]. https://doi.org/10.1016/j.isci.2020.101053
Varderidou-Minasian, S., Verheijen, B. M., Schätzle, P., Hoogenraad, C. C., Pasterkamp, R. J., & Altelaar, M. (2020). Deciphering the Proteome Dynamics during Development of Neurons Derived from Induced Pluripotent Stem Cells. Journal of Proteome Research, 19( 6), 2391-2403. https://doi.org/10.1021/acs.jproteome.0c00070
Hoogenraad, C. C., & Riol-Blanco, L. (2020). Interleukin-17: A Social Cytokine. Cell, 181(3), 517-519. https://doi.org/10.1016/j.cell.2020.03.060
Lindhout, F. W., Kooistra, R., Portegies, S., Herstel, L. J., Stucchi, R., Snoek, B. L., Altelaar, M., MacGillavry, H. D., Wierenga, C. J., & Hoogenraad, C. C. (2020). Quantitative mapping of transcriptome and proteome dynamics during polarization of human iPSC-derived neurons. eLife, 9. https://doi.org/10.7554/eLife.58124
He, L., Kooistra, R., Das, R., Oudejans, E., van Leen, E., Ziegler, J., Portegies, S., de Haan, B., Altena, A. V. R., Stucchi, R., Altelaar, A. F. M., Wieser, S., Krieg, M., Hoogenraad, C. C., & Harterink, M. (2020). Cortical anchoring of the microtubule cytoskeleton is essential for neuron polarity. eLife, 9, [e55111]. https://doi.org/10.7554/eLife.55111
Cao, Y., Lipka, J., Stucchi, R., Burute, M., Pan, X., Portegies, S., Tas, R., Willems, J., Will, L., MacGillavry, H., Altelaar, M., Kapitein, L. C., Harterink, M., & Hoogenraad, C. C. (2020). Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule Organization. Current Biology, 30(5), 899-908.e6. https://doi.org/10.1016/j.cub.2019.12.056
Ferrari, L., Stucchi, R., Konstantoulea, K., van de Kamp, G., Kos, R., Geerts, W. J. C., van Bezouwen, L. S., Förster, F. G., Altelaar, M., Hoogenraad, C. C., & Rüdiger, S. G. D. (2020). Arginine π-stacking drives binding to fibrils of the Alzheimer protein Tau. Nature Communications, 11(1), 1-13. [571]. https://doi.org/10.1038/s41467-019-13745-7
Lesuis, S. L., Timmermans, W., Lucassen, P. J., Hoogenraad, C. C., & Krugers, H. J. (2020). Glucocorticoid and β-adrenergic regulation of hippocampal dendritic spines. Journal of Neuroendocrinology, 32(1), [e12811]. https://doi.org/10.1111/jne.12811
2019
Scholarly publications
Ferrari, L., Stucci, R., Konstantoulea, A., van, D. K. G., Kos, R., Geerts, WJ., Forster, FG., Altelaar, M., Hoogenraad, C., & Rudiger, SG. (2019, Jan). Fibril formation rewires interactome of the Alzheimer protein Tau by π-stacking. https://doi.org/10.1101/522284
Freal, A., & Hoogenraad, C. C. (2019). Neuronal Cytoskeleton: Presynaptic Boutons as Hotspots for Activity-Dependent Microtubule Nucleation. Current Biology, 29(24), R1307-R1309. https://doi.org/10.1016/j.cub.2019.11.011
Stanganello, E., Zahavi, E. E., Burute, M., Smits, J., Jordens, I., Maurice, M. M., Kapitein, L. C., & Hoogenraad, C. C. (2019). Wnt Signaling Directs Neuronal Polarity and Axonal Growth. iScience, 13, 318-327. https://doi.org/10.1016/j.isci.2019.02.029
Pan, X., Cao, Y., Stucchi, R., Hooikaas, P. J., Portegies, S., Will, L., Martin, M., Akhmanova, A., Harterink, M., & Hoogenraad, C. C. (2019). MAP7D2 Localizes to the Proximal Axon and Locally Promotes Kinesin-1-Mediated Cargo Transport into the Axon. Cell Reports, 26(8), 1988-1999.e6. https://doi.org/10.1016/j.celrep.2019.01.084
Frias, C. P., Liang, J., Bresser, T., Scheefhals, L., van Kesteren, M., van Dorland, R., Hu, H. Y., Bodzeta, A., van Bergen En Henegouwen, P. M. P., Hoogenraad, C. C., & Wierenga, C. J. (2019). Semaphorin4D Induces Inhibitory Synapse Formation by Rapid Stabilization of Presynaptic Boutons via MET Coactivation. Journal of Neuroscience, 39(22), 4221-4237. https://doi.org/10.1523/JNEUROSCI.0215-19.2019
Hu, H. Y., Kruijssen, D. L. H., Frias, C. P., Rózsa, B., Hoogenraad, C. C., & Wierenga, C. J. (2019). Endocannabinoid Signaling Mediates Local Dendritic Coordination between Excitatory and Inhibitory Synapses. Cell Reports, 27(3), 666-675.e5. https://doi.org/10.1016/j.celrep.2019.03.078
van de Willige, D., Hummel, J. J., Alkemade, C., Kahn, O. I., Au, F. K., Qi, R. Z., Dogterom, M., Koenderink, G. H., Hoogenraad, C. C., & Akhmanova, A. (2019). Cytolinker Gas2L1 regulates axon morphology through microtubule-modulated actin stabilization. EMBO Reports, 20(11), [e47732]. https://doi.org/10.15252/embr.201947732
Lipka, J., & Hoogenraad, C. C. (2019). Solving the Mysteries of Dementia: FTD Mutant Tau Impairs Structural Axon Initial Segment Plasticity. Neuron, 104(3), 429-430. https://doi.org/10.1016/j.neuron.2019.10.021
Will, L., Portegies, S., van Schelt, J., van Luyk, M., Jaarsma, D., & Hoogenraad, C. C. (2019). Dynein activating adaptor BICD2 controls radial migration of upper-layer cortical neurons in vivo. Acta neuropathologica communications, 7(1), 162. https://doi.org/10.1186/s40478-019-0827-y
Harterink, M., Vocking, K., Pan, X., Soriano Jerez, E. M., Slenders, L., Fréal, A., Tas, R. P., Van De Wetering, W. J., Timmer, K., Motshagen, J., Van Beuningen, S. F. B., Kapitein, L. C., Geerts, W. J. C., Post, J. A., & Hoogenraad, C. C. (2019). TRIM46 Organizes Microtubule Fasciculation in the Axon Initial Segment. Journal of Neuroscience, 39(25), 4864-4873. https://doi.org/10.1523/JNEUROSCI.3105-18.2019
https://dspace.library.uu.nl/bitstream/handle/1874/388379/4864.full.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/388379/4864.full.pdf?sequence=1
Scheefhals, N., Catsburg, L. A. E., Westerveld, M. L., Blanpied, T. A., Hoogenraad, C. C., & Macgillavry, H. D. (2019). Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5. Cell Reports, 29(2), 258-269, e8. https://doi.org/10.1016/j.celrep.2019.08.102
van Coevorden-Hameete, M. H., de Bruijn, M. A. A. M., de Graaff, E., Bastiaansen, D. A. E. M., Schreurs, M. W. J., Demmers, J. A. A., Ramberger, M., Hulsenboom, E. S. P., Nagtzaam, M. M. P., Boukhrissi, S., Veldink, J. H., Verschuuren, J. J. G. M., Hoogenraad, C. C., Sillevis Smitt, P. A. E., & Titulaer, M. J. (2019). The expanded clinical spectrum of anti-GABABR encephalitis and added value of KCTD16 autoantibodies. Brain, 142(6), 1631-1643. https://doi.org/10.1093/brain/awz094
Fréal, A., Rai, D., Tas, R. P., Pan, X., Katrukha, E. A., van de Willige, D., Stucchi, R., Aher, A., Yang, C., Altelaar, A. F. M., Vocking, K., Post, J. A., Harterink, M., Kapitein, L. C., Akhmanova, A., & Hoogenraad, C. C. (2019). Feedback-Driven Assembly of the Axon Initial Segment. Neuron, 104(2), P305-321.E8. https://doi.org/10.1016/j.neuron.2019.07.029
Farías, G. G., Fréal, A., Tortosa, E., Stucchi, R., Pan, X., Portegies, S., Will, L., Altelaar, M., & Hoogenraad, C. C. (2019). Feedback-Driven Mechanisms between Microtubules and the Endoplasmic Reticulum Instruct Neuronal Polarity. Neuron, 102(1), 184-201.e8. https://doi.org/10.1016/j.neuron.2019.01.030
Hooikaas, P. J., Martin, M., Mühlethaler, T., Kuijntjes, G. J., Peeters, C. A. E., Katrukha, E. A., Ferrari, L., Stucchi, R., Verhagen, D. G. F., Van Riel, W. E., Grigoriev, I., Altelaar, A. F. M., Hoogenraad, C. C., Rüdiger, S. G. D., Steinmetz, M. O., Kapitein, L. C., & Akhmanova, A. (2019). MAP7 family proteins regulate kinesin-1 recruitment and activation. Journal of Cell Biology, 218(4), 1298-1318. https://doi.org/10.1083/jcb.201808065
Lindhout, F. W., Cao, Y., Kevenaar, J. T., Bodzęta, A., Stucchi, R., Boumpoutsari, M. M., Katrukha, E. A., Altelaar, M., MacGillavry, H. D., & Hoogenraad, C. C. (2019). VAP-SCRN1 interaction regulates dynamic endoplasmic reticulum remodeling and presynaptic function. EMBO Journal, 38(20), [e101345]. https://doi.org/10.15252/embj.2018101345
Koopmans, F., van Nierop, P., Andres-Alonso, M., Byrnes, A., Cijsouw, T., Coba, M. P., Cornelisse, L. N., Farrell, R. J., Goldschmidt, H. L., Howrigan, D. P., Hussain, N. K., Imig, C., de Jong, A. P. H., Jung, H., Kohansalnodehi, M., Kramarz, B., Lipstein, N., Lovering, R. C., MacGillavry, H., ... Verhage, M. (2019). SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse. Neuron, 103(2), 217-234. https://doi.org/10.1016/j.neuron.2019.05.002
2018
Scholarly publications
Karasmanis, E. P., Phan, C. T., Angelis, D., Kesisova, I. A., Hoogenraad, C. C., McKenney, R. J., & Spiliotis, E. T. (2018). Polarity of Neuronal Membrane Traffic Requires Sorting of Kinesin Motor Cargo during Entry into Dendrites by a Microtubule-Associated Septin. Developmental Cell, 46(2), 204-218.e7. https://doi.org/10.1016/j.devcel.2018.06.013
Karasmanis, E. P., Phan, C-T., Angelis, D., Kesisova, I. A., Hoogenraad, C. C., McKenney, R. J., & Spiliotis, E. T. (2018). Erratum: Polarity of Neuronal Membrane Traffic Requires Sorting of Kinesin Motor Cargo during Entry into Dendrites by a Microtubule-Associated Septin. Developmental Cell, 46(4), 518-524. https://doi.org/10.1016/j.devcel.2018.08.004
MacGillavry, H. D., & Hoogenraad, C. C. (2018). Membrane trafficking and cytoskeletal dynamics in neuronal function. Molecular and Cellular Neurosciences, 91, 1-2. https://doi.org/10.1016/j.mcn.2018.08.003
Gumy, L. F., & Hoogenraad, C. C. (2018). Local mechanisms regulating selective cargo entry and long-range trafficking in axons. Current Opinion in Neurobiology, 51, 23-28. https://doi.org/10.1016/j.conb.2018.02.007
Tortosa, E., & Hoogenraad, C. C. (2018). Polarized trafficking: the palmitoylation cycle distributes cytoplasmic proteins to distinct neuronal compartments. Current Opinion in Cell Biology, 50, 64-71. https://doi.org/10.1016/j.ceb.2018.02.004
Mikhaylova, M., Bär, J., van Bommel, B., Schätzle, P., YuanXiang, P., Raman, R., Hradsky, J., Konietzny, A., Loktionov, E. Y., Reddy, P. P., Lopez-Rojas, J., Spilker, C., Kobler, O., Raza, S. A., Stork, O., Hoogenraad, C. C., & Kreutz, M. R. (2018). Caldendrin Directly Couples Postsynaptic Calcium Signals to Actin Remodeling in Dendritic Spines. Neuron, 97(5), 1110-1125.e14. https://doi.org/10.1016/j.neuron.2018.01.046
Dumbacher, M., Van Dooren, T., Princen, K., De Witte, K., Farinelli, M., Lievens, S., Tavernier, J., Dehaen, W., Wera, S., Winderickx, J., Allasia, S., Kilonda, A., Spieser, S., Marchand, A., Chaltin, P., Hoogenraad, C. C., & Griffioen, G. (2018). Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer's disease. Molecular Neurodegeneration, 13(1), [50]. https://doi.org/10.1186/s13024-018-0283-3
Akhmanova, A., & Hoogenraad, C. C. (2018). More is not always better: hyperglutamylation leads to neurodegeneration. EMBO Journal, 37(23). https://doi.org/10.15252/embj.2018101023
Kahn, O. I., Schätzle, P., van de Willige, D., Tas, R. P., Lindhout, F. W., Portegies, S., Kapitein, L. C., & Hoogenraad, C. C. (2018). APC2 controls dendrite development by promoting microtubule dynamics. Nature Communications, 9, [2773]. https://doi.org/10.1038/s41467-018-05124-5
Harterink, M., Edwards, S. L., de Haan, B., Yau, K. W., van den Heuvel, S., Kapitein, L. C., Miller, K. G., & Hoogenraad, C. C. (2018). Local microtubule organization promotes cargo transport in C. elegans dendrites. Journal of Cell Science, 131(20), [ jcs223107]. https://doi.org/10.1242/jcs.223107
Cunha-Ferreira, I., Chazeau, A., Buijs, R. R., Stucchi, R., Will, L., Pan, X., Adolfs, Y., van der Meer, C., Wolthuis, J. C., Kahn, O. I., Schätzle, P., Altelaar, M., Pasterkamp, R. J., Kapitein, L. C., & Hoogenraad, C. C. (2018). The HAUS Complex Is a Key Regulator of Non-centrosomal Microtubule Organization during Neuronal Development. Cell Reports, 24(4), 791-800. https://doi.org/10.1016/j.celrep.2018.06.093
Stucchi, R., Plucińska, G., Hummel, J. J. A., Zahavi, E. E., Guerra San Juan, I., Klykov, O., Scheltema, R. A., Altelaar, A. F. M., & Hoogenraad, C. C. (2018). Regulation of KIF1A-Driven Dense Core Vesicle Transport: Ca2+/CaM Controls DCV Binding and Liprin-α/TANC2 Recruits DCVs to Postsynaptic Sites. Cell Reports, 24(3), 685-700. https://doi.org/10.1016/j.celrep.2018.06.071
Schätzle, P., Esteves da Silva, M., Tas, R. P., Katrukha, E. A., Hu, H. Y., Wierenga, C. J., Kapitein, L. C., & Hoogenraad, C. C. (2018). Activity-Dependent Actin Remodeling at the Base of Dendritic Spines Promotes Microtubule Entry. Current Biology, 28(13), 2081-2093.e6. https://doi.org/10.1016/j.cub.2018.05.004
Other output
Pereira Frias, C. S., Bresser, T., Scheefhals, L., van Bergen en Henegouwen, P. M. P., Hoogenraad, C. C., & Wierenga, C. J. (2018). Molecular pathway underlying bouton stabilization by Semaphorin4D during inhibitory synapse formation.. https://doi.org/10.1101/100271
2017
Scholarly publications
Adrian, M., Kusters, R., Storm, C., Hoogenraad, C. C., & Kapitein, L. C. (2017). Probing the Interplay between Dendritic Spine Morphology and Membrane-Bound Diffusion. Biophysical Journal, 113(10), 2261-2270. https://doi.org/10.1016/j.bpj.2017.06.048
Janssen, A. F. J., Tas, R. P., van Bergeijk, P., Oost, R., Hoogenraad, C. C., & Kapitein, L. C. (2017). Myosin-V Induces Cargo Immobilization and Clustering at the Axon Initial Segment. Frontiers in Cellular Neuroscience, 11, [260]. https://doi.org/10.3389/fncel.2017.00260
Tas, R. P., Chazeau, A., Cloin, B. M. C., Lambers, M. L. A., Hoogenraad, C. C., & Kapitein, L. C. (2017). Differentiation between Oppositely Oriented Microtubules Controls Polarized Neuronal Transport. Neuron, 96(6), 1264-1271. https://doi.org/10.1016/j.neuron.2017.11.018
Dörr, J. M., van Coevorden-Hameete, M. H., Hoogenraad, C. C., & Killian, J. A. (2017). Solubilization of human cells by the styrene-maleic acid copolymer: Insights from fluorescence microscopy. Biochimica et Biophysica Acta, 1859(11), 2155-2160. https://doi.org/10.1016/j.bbamem.2017.08.010
Derks, N. AV., Krugers, H. J., Hoogenraad, C. C., Joëls, M., & Sarabdjitsingh, R. A. (2017). Effects of early life stress on rodent hippocampal synaptic plasticity: a systematic review. Current Opinion in Behavioral Sciences, 14, 155-166. https://doi.org/10.1016/j.cobeha.2017.03.005
Miermans, C. A., Kusters, R. P. T., Hoogenraad, C. C., & Storm, C. (2017). Biophysical model of the role of actin remodeling on dendritic spine morphology. PLoS One, 12(2), [e0170113]. https://doi.org/10.1371/journal.pone.0170113
Lombardi, L., Persiconi, I., Gallo, A., Hoogenraad, C. C., & De Stefano, M. E. (2017). NGF-dependent axon growth and regeneration are altered in sympathetic neurons of dystrophic mdx mice. Molecular and Cellular Neurosciences, 80, 1-17. https://doi.org/10.1016/j.mcn.2017.01.006
Abil, Z., Gumy, L. F., Zhao, H., & Hoogenraad, C. C. (2017). Inducible Control of mRNA Transport Using Reprogrammable RNA-Binding Proteins. ACS Synthetic Biology, 6(6), 950-956. https://doi.org/10.1021/acssynbio.7b00025
van den Berg, R., Hoogenraad, C. C., & Hintzen, R. Q. (2017). Axonal transport deficits in multiple sclerosis: spiraling into the abyss. Acta Neuropathologica, 134(1), 1-14. https://doi.org/10.1007/s00401-017-1697-7
Katrukha, E. A., Mikhaylova, M., van Brakel, H. X., van Bergen En Henegouwen, P. M., Akhmanova, A., Hoogenraad, C. C., & Kapitein, L. C. (2017). Probing cytoskeletal modulation of passive and active intracellular dynamics using nanobody-functionalized quantum dots. Nature Communications, 8, [14772]. https://doi.org/10.1038/ncomms14772
Harterink, M., Santos Esteves da Silva, M., Will, L., Turan, J., Ibrahim, A., Lang, A. E., Van Battum, E. Y., Pasterkamp, R. J., Kapitein, L. C., Kudryashov, D., Barres, B. A., Hoogenraad, C. C., & Zuchero, J. B. (2017). DeActs: genetically encoded tools for perturbing the actin cytoskeleton in single cells. Nature Methods, 14(5), 479-482. https://doi.org/10.1038/nmeth.4257
https://dspace.library.uu.nl/bitstream/handle/1874/359001/deacts.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/359001/deacts.pdf?sequence=1
Gumy, L. F., Katrukha, E. A., Grigoriev, I., Jaarsma, D., Kapitein, L. C., Akhmanova, A., & Hoogenraad, C. C. (2017). MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus KIF5-Dependent Cargo Transport in Sensory Neurons. Neuron, 94(2), 347-362.e7. https://doi.org/10.1016/j.neuron.2017.03.046
https://dspace.library.uu.nl/bitstream/handle/1874/359343/1_s2.0_S0896627317302908_main.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/359343/1_s2.0_S0896627317302908_main.pdf?sequence=1
Tortosa Binacua, E., Adolfs, Y., Fukata, M., Pasterkamp, R. J., Kapitein, L. C., & Hoogenraad, C. C. (2017). Dynamic Palmitoylation Targets MAP6 to the Axon to Promote Microtubule Stabilization during Neuronal Polarization. Neuron, 94(4), 809-825.e7. https://doi.org/10.1016/j.neuron.2017.04.042
van Coevorden-Hameete, M. H., van Beuningen, S. F. B., Perrenoud, M., Will, L. M., Hulsenboom, E., Demonet, J-F., Sabater, L., Kros, J. M., Verschuuren, J. J. G. M., Titulaer, M. J., de Graaff, E., Sillevis Smitt, P. A. E., & Hoogenraad, C. (2017). Antibodies to TRIM46 are associated with paraneoplastic neurological syndromes. Annals of Clinical and Translational Neurology, 4(9), 680-686. https://doi.org/10.1002/acn3.396
Cloin, B. M. C., De Zitter, E., Salas Pastene, D., Gielen, V., Folkers, G. E., Mikhaylova, M., Bergeler, M., Krajnik, B., Harvey, J., Hoogenraad, C. C., Van Meervelt, L., Dedecker, P., & Kapitein, L. C. (2017). Efficient switching of mCherry fluorescence using chemical caging. Proceedings of the National Academy of Sciences of the United States of America, 114(27), 7013-7018. https://doi.org/10.1073/pnas.1617280114
van Riel, W. E., Rai, A., Bianchi, S., Katrukha, E. A., Liu, Q., Heck, A. J., Hoogenraad, C. C., Steinmetz, M. O., Kapitein, L. C., & Akhmanova, A. (2017). Kinesin-4 KIF21B is a potent microtubule pausing factor. eLife, 6, [e24746]. https://doi.org/10.7554/eLife.24746
Frese, C. K., Mikhaylova, M., Stucchi, R., Gautier, V., Liu, Q., Mohammed, S., Heck, A. J. R., Altelaar, A. F. M., & Hoogenraad, C. C. (2017). Quantitative Map of Proteome Dynamics during Neuronal Differentiation. Cell Reports, 18(6), 1527-1542. https://doi.org/10.1016/j.celrep.2017.01.025
Post, H., Penning, R., Fitzpatrick, M., Garrigues, L. B., Wu, W., Mac Gillavry, H. D., Hoogenraad, C. C., Heck, A. J. R., & Altelaar, A. F. M. (2017). Robust, Sensitive, and Automated Phosphopeptide Enrichment Optimized for Low Sample Amounts Applied to Primary Hippocampal Neurons. Journal of Proteome Research, 16(2), 728-737. https://doi.org/10.1021/acs.jproteome.6b00753
2016
Scholarly publications
Emoto, K., Wong, R., Huang, E., & Hoogenraad, C. (2016). Dendrites: Development and disease. Springer Japan. https://doi.org/10.1007/978-4-431-56050-0
Tortosa Binacua, E., Kapitein, L. C., & Hoogenraad, C. C. (2016). Microtubule Organization and Microtubule-Associated Proteins (MAPs). In K. Emoto, R. Wong, E. Huang, & C. Hoogenraad (Eds.), Dendrites: Development and Disease (pp. 31). Springer. https://doi.org/10.1007/978-4-431-56050-0_3
Fréal, A., Fassier, C., Le Bras, B., Bullier, E., de Gois, S., Hazan, J., Hoogenraad, C. C., & Couraud, F. (2016). Cooperative Interactions between 480 kDa Ankyrin-G and EB proteins assemble the axon initial segment. Journal of Neuroscience, 36(16), 4421-4433. https://doi.org/10.1523/JNEUROSCI.3219-15.2016
Derks, N. A. V., Krugers, H. J., Hoogenraad, C. C., Joëls, M., & Sarabdjitsingh, R. A. (2016). Effects of Early Life Stress on Synaptic Plasticity in the Developing Hippocampus of Male and Female Rats. PLoS One, 11(10), [e0164551]. https://doi.org/10.1371/journal.pone.0164551
Wu, J., de Heus, C., Liu, Q., Bouchet, B. P., Noordstra, I., Jiang, K., Hua, S., Martin, M., Yang, C., Grigoriev, I., Katrukha, E. A., Altelaar, A. F. M., Hoogenraad, C. C., Qi, R. Z., Klumperman, J., & Akhmanova, A. (2016). Molecular Pathway of Microtubule Organization at the Golgi Apparatus. Developmental Cell, 39(1), 44–60. https://doi.org/10.1016/j.devcel.2016.08.009
Hoogenraad, C. C., & Akhmanova, A. (2016). Bicaudal D Family of Motor Adaptors: Linking Dynein Motility to Cargo Binding. Trends in Cell Biology, 26(5), 327-40. https://doi.org/10.1016/j.tcb.2016.01.001
Yau, K. W., Schätzle, P., Tortosa, E., Pagès, S., Holtmaat, A., Kapitein, L. C., & Hoogenraad, C. (2016). Dendrites In Vitro and In Vivo Contain Microtubules of Opposite Polarity and Axon Formation Correlates with Uniform Plus-End-Out Microtubule Orientation. Journal of Neuroscience, 36(4), 1071-85. https://doi.org/10.1523/JNEUROSCI.2430-15.2016
Chazeau, A., Katrukha, E. A., Hoogenraad, C. C., & Kapitein, L. C. (2016). Studying neuronal microtubule organization and microtubule-associated proteins using single molecule localization microscopy. Methods in Cell Biology, 131, 127-49. https://doi.org/10.1016/bs.mcb.2015.06.017
https://dspace.library.uu.nl/bitstream/handle/1874/343664/Studying.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/343664/Studying.pdf?sequence=1
Schätzle, P., Kapitein, L. C., & Hoogenraad, C. C. (2016). Live imaging of microtubule dynamics in organotypic hippocampal slice cultures. Methods in Cell Biology, 131, 107-126. https://doi.org/10.1016/bs.mcb.2015.06.006
https://dspace.library.uu.nl/bitstream/handle/1874/343663/Live.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/343663/Live.pdf?sequence=1
van den Berg, R., Laman, J. D., van Meurs, M., Hintzen, R. Q., & Hoogenraad, C. C. (2016). Rotarod motor performance and advanced spinal cord lesion image analysis refine assessment of neurodegeneration in experimental autoimmune encephalomyelitis. Journal of Neuroscience Methods, 262, 66-76. https://doi.org/10.1016/j.jneumeth.2016.01.013
Lipka, J., Kapitein, L. C., Jaworski, J., & Hoogenraad, C. C. (2016). Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites. EMBO Journal, 35(3), 302-18. https://doi.org/10.15252/embj.201592929
https://dspace.library.uu.nl/bitstream/handle/1874/344421/protein.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/344421/protein.pdf?sequence=1
Kuijpers, M., van de Willige, D., Freal, A., Chazeau, A., Franker, M. A., Hofenk, J., Rodrigues, R. J. C., Kapitein, L. C., Akhmanova, A., Jaarsma, D., & Hoogenraad, C. C. (2016). Dynein Regulator NDEL1 Controls Polarized Cargo Transport at the Axon Initial Segment. Neuron, 89(3), 461-471. https://doi.org/10.1016/j.neuron.2016.01.022
https://dspace.library.uu.nl/bitstream/handle/1874/344420/Dynein.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/344420/Dynein.pdf?sequence=1
Harterink, M., van Bergeijk, P., Allier, C., de Haan, B., van den Heuvel, S., Hoogenraad, C. C., & Kapitein, L. C. (2016). Light-controlled intracellular transport in Caenorhabditis elegans. Current Biology, 26(4), PR153-R154. https://doi.org/10.1016/j.cub.2015.12.016
van Beuningen, S. F., & Hoogenraad, C. C. (2016). Neuronal polarity: remodeling microtubule organization. Current Opinion in Neurobiology, 39, 1-7. https://doi.org/10.1016/j.conb.2016.02.003
Kevenaar, J. T., Bianchi, S., van Spronsen, M., Olieric, N., Lipka, J., Frias, C. P., Mikhaylova, M., Harterink, M., Keijzer, N., Wulf, P. S., Hilbert, M., Kapitein, L. C., de Graaff, E., Akhmanova, A., Steinmetz, M. O., & Hoogenraad, C. C. (2016). Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity. Current Biology, 26(7), 849-861. https://doi.org/10.1016/j.cub.2016.01.048
https://dspace.library.uu.nl/bitstream/handle/1874/343660/Microtubule.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/343660/Microtubule.pdf?sequence=1
van de Willige, D., Hoogenraad, C. C., & Akhmanova, A. (2016). Microtubule plus-end tracking proteins in neuronal development. Cellular and Molecular Life Sciences, 73(10), 2053-77. https://doi.org/10.1007/s00018-016-2168-3
Josifova, D. J., Monroe, G. R., Tessadori, F., de Graaff, E., van der Zwaag, B., Mehta, S. G., Harakalova, M., Duran, K. J., Savelberg, S. M. C., Nijman, I. J., Jungbluth, H., Hoogenraad, C. C., Bakkers, J., Knoers, N. V., Firth, H. V., Beales, P. L., van Haaften, G., van Haelst, M. M., & DDD Study (2016). Heterozygous KIDINS220/ARMS nonsense variants cause spastic paraplegia, intellectual disability, nystagmus, and obesity. Human Molecular Genetics, 25(11), 2158-2167. https://doi.org/10.1093/hmg/ddw082
Padzik, A., Deshpande, P., Hollos, P., Franker, M., Rannikko, E. H., Cai, D., Prus, P., Mågård, M., Westerlund, N., Verhey, K. J., James, P., Hoogenraad, C. C., & Coffey, E. T. (2016). KIF5C S176 Phosphorylation Regulates Microtubule Binding and Transport Efficiency in Mammalian Neurons. Frontiers in Cellular Neuroscience [E], 10. https://doi.org/10.3389/fncel.2016.00057
Franker, M. A., Esteves da Silva, M., Tas, R. P., Tortosa, E., Cao, Y., Frias, C. P., Janssen, A. F. J., Wulf, P. S., Kapitein, L. C., & Hoogenraad, C. C. (2016). Three-Step Model for Polarized Sorting of KIF17 into Dendrites. Current Biology, 26(13), 1705-1712. https://doi.org/10.1016/j.cub.2016.04.057
https://dspace.library.uu.nl/bitstream/handle/1874/341485/Model.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/341485/Model.pdf?sequence=1
Ruane, P. T., Gumy, L. F., Bola, B., Anderson, B., Wozniak, M. J., Hoogenraad, C. C., & Allan, V. J. (2016). Tumour Suppressor Adenomatous Polyposis Coli (APC) localisation is regulated by both Kinesin-1 and Kinesin-2. Scientific Reports, 6, [27456]. https://doi.org/10.1038/srep27456
van Coevorden-Hameete, M. H., Titulaer, M. J., Schreurs, M. W. J., de Graaff, E., Sillevis Smitt, P. A. E., & Hoogenraad, C. C. (2016). Detection and Characterization of Autoantibodies to Neuronal Cell-Surface Antigens in the Central Nervous System. Frontiers in Molecular Neuroscience, 9. https://doi.org/10.3389/fnmol.2016.00037
Grubb, M. S., Hoogenraad, C. C., Schwabe, L., & López-Bendito, G. (2016). Moving on: mobility for early-career neuroscientists. European Journal of Neuroscience, 44(6), 2285–2290. https://doi.org/10.1111/ejn.13339
Waaijers, S., Muñoz, J., Berends, C., Ramalho, J. J., Goerdayal, S. S., Low, T. Y., Zoumaro-Djayoon, A. D., Hoffmann, M., Koorman, T., Tas, R. P., Harterink, M., Seelk, S., Kerver - Stumpfova, J., Hoogenraad, C. C., Bossinger, O., Tursun, B., van den Heuvel, S., Heck, A. J. R., & Boxem, M. (2016). A tissue-specific protein purification approach in Caenorhabditis elegans identifies novel interaction partners of DLG-1/Discs large. BMC Biology, 14, [66]. https://doi.org/10.1186/s12915-016-0286-x
https://dspace.library.uu.nl/bitstream/handle/1874/341483/protein.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/341483/protein.pdf?sequence=1
van Bergeijk, P., Hoogenraad, C. C., & Kapitein, L. C. (2016). Right Time, Right Place: Probing the Functions of Organelle Positioning. Trends in Cell Biology, 26(2), 121-134. https://doi.org/10.1016/j.tcb.2015.10.001
https://dspace.library.uu.nl/bitstream/handle/1874/329577/Right.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/329577/Right.pdf?sequence=1
2015
Scholarly publications
Adrian, M., Hoogenraad, C. C., & Kapitein, L. C. (2015). Positioning of Rab11-positive recycling endosomes regulates synapse architecture and growth cone dynamics. Molecular Biology of the Cell, 26(25). https://doi.org/10.1091/mbc.E15-09-0674
van Beuningen, S. F. B., Will, L., Harterink, M., Chazeau, A., van Battum, E. Y., Frias, C. P., Franker, M. A. M., Katrukha, E. A., Stucchi, R., Vocking, K., Antunes, A. T., Slenders, L., Doulkeridou, S., Sillevis Smitt, P., Altelaar, A. F. M., Post, J. A., Akhmanova, A., Pasterkamp, R. J., Kapitein, L. C., ... Hoogenraad, C. C. (2015). TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays. Neuron, 88(6), 1208-1226. https://doi.org/10.1016/j.neuron.2015.11.012
van Erp, S., van den Heuvel, D. M. A., Fujita, Y., Robinson, R. A., Hellemons, A. J. C. G. M., Adolfs, Y., Van Battum, E. Y., Blokhuis, A. M., Kuijpers, M., Demmers, J. A. A., Hedman, H., Hoogenraad, C. C., Siebold, C., Yamashita, T., & Pasterkamp, R. J. (2015). Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases. Developmental Cell, 35(5), 537-552. https://doi.org/10.1016/j.devcel.2015.11.008
Akhmanova, A., & Hoogenraad, C. C. (2015). Microtubule minus-end-targeting proteins. Current Biology, 25(4), R162-71. https://doi.org/10.1016/j.cub.2014.12.027
MacGillavry, H. D., & Hoogenraad, C. C. (2015). The internal architecture of dendritic spines revealed by super-resolution imaging: What did we learn so far? Experimental Cell Research, 335(2), 180-6. https://doi.org/10.1016/j.yexcr.2015.02.024
Joëls, M., Hoogenraad, C. C., Poirazi, P., & Di Luca, M. (2015). The Hitchhiker's Guide to a Neuroscience Career. Neuron, 86(3), 613-6. https://doi.org/10.1016/j.neuron.2015.04.002
Franssen, E. H. P., Zhao, R-R., Koseki, H., Kanamarlapudi, V., Hoogenraad, C. C., Eva, R., & Fawcett, J. W. (2015). Exclusion of integrins from CNS axons is regulated by Arf6 activation and the AIS. Journal of Neuroscience, 35(21), 8359-75. https://doi.org/10.1523/JNEUROSCI.2850-14.2015
Kapitein, L. C., & Hoogenraad, C. C. (2015). Building the Neuronal Microtubule Cytoskeleton. Neuron, 87(3), 492-506. https://doi.org/10.1016/j.neuron.2015.05.046
https://dspace.library.uu.nl/bitstream/handle/1874/329578/39_main.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/329578/39_main.pdf?sequence=1
Mikhaylova, M., Cloin, B. M. C., Finan, K., van den Berg, R., Teeuw, J., Kijanka, M. M., Sokolowski, M., Katrukha, E. A., Maidorn, M., Opazo, F., Moutel, S., Vantard, M., Perez, F., van Bergen en Henegouwen, P. M. P., Hoogenraad, C. C., Ewers, H., & Kapitein, L. C. (2015). Resolving bundled microtubules using anti-tubulin nanobodies. Nature Communications [E], 6, [7933]. https://doi.org/10.1038/ncomms8933
https://dspace.library.uu.nl/bitstream/handle/1874/324920/33.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/324920/33.pdf?sequence=1
Kevenaar, J. T., & Hoogenraad, C. C. (2015). The axonal cytoskeleton: from organization to function. Frontiers in Molecular Neuroscience, 8, [44]. https://doi.org/10.3389/fnmol.2015.00044
Esteves da Silva, M., Adrian, M., Schätzle, P., Lipka, J., Watanabe, T., Cho, S., Futai, K., Wierenga, C. J., Kapitein, L. C., & Hoogenraad, C. C. (2015). Positioning of AMPA Receptor-Containing Endosomes Regulates Synapse Architecture. Cell Reports [E], 13(5), 933-943. https://doi.org/10.1016/j.celrep.2015.09.062
Jaarsma, D., & Hoogenraad, C. C. (2015). Cytoplasmic dynein and its regulatory proteins in Golgi pathology in nervous system disorders. Frontiers in Neuroscience, 9, [397]. https://doi.org/10.3389/fnins.2015.00397
https://dspace.library.uu.nl/bitstream/handle/1874/324917/fnins_09_00397.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/324917/fnins_09_00397.pdf?sequence=1
van Coevorden-Hameete, M. H., de Graaff, E., Titulaer, M. J., Hulsenboom, E., Sabater, L., Hoogenraad, C. C., & Sillevis Smitt, P. A. (2015). Plasticity-related gene 5: A novel surface autoantigen in paraneoplastic cerebellar degeneration. Neurology® neuroimmunology & neuroinflammation, 2(5), [e156]. https://doi.org/10.1212/NXI.0000000000000156
https://dspace.library.uu.nl/bitstream/handle/1874/324902/Hameete.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/324902/Hameete.pdf?sequence=1
van Bergeijk, P., Adrian, M., Hoogenraad, C. C., & Kapitein, L. C. (2015). Optogenetic control of organelle transport and positioning. Nature, 518, 111–114 . https://doi.org/10.1038/nature14128
https://dspace.library.uu.nl/bitstream/handle/1874/320995/nature14128.pdf?sequence=2
https://dspace.library.uu.nl/bitstream/handle/1874/320995/nature14128.pdf?sequence=2
Cloin, B., Hoogenraad, C., Mikhaylova, M., & Kapitein, L. (2015). Single molecule localization microscopy to study neuronal microtubule organization. In Immunocytochemistry and Related Techniques (pp. 389-408). (Neuromethods; Vol. 101). Humana Press. https://doi.org/10.1007/978-1-4939-2313-7_21
https://dspace.library.uu.nl/bitstream/handle/1874/428547/978_1_4939_2313_7_21.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/428547/978_1_4939_2313_7_21.pdf?sequence=1
2014
Scholarly publications
Kuijpers, M., van Dis, V., Haasdijk, E. D., Harterink, M., Vocking, K., Post, J. A., Scheper, W., Hoogenraad, C. C., & Jaarsma, D. (2014). Amyotrophic lateral sclerosis (ALS)-associated VAPB-P56S inclusions represent an ER quality control compartment. Acta neuropathologica communications, 1(1), [24]. https://doi.org/10.1186/2051-5960-1-24
van Dis, V., Kuijpers, M., Haasdijk, E. D., Teuling, E., Oakes, S. A., Hoogenraad, C. C., & Jaarsma, D. (2014). Golgi fragmentation precedes neuromuscular denervation and is associated with endosome abnormalities in SOD1-ALS mouse motor neurons. Acta neuropathologica communications, 2, 38. https://doi.org/10.1186/2051-5960-2-38
Hessel, E. V. S., de Wit, M., Wolterink-Donselaar, I. G., Karst, H., de Graaff, E., van Lith, H. A., de Bruijn, E., de Sonnaville, S., Verbeek, N. E., Lindhout, D., de Kovel, C. G. F., Koeleman, B. P. C., van Kempen, M., Brilstra, E., Cuppen, E., Loos, M., Spijker, S. S., Kan, A. A., Baars, S. E., ... de Graan, P. N. E. (2014). Identification of Srp9 as a febrile seizure susceptibility gene. Annals of Clinical and Translational Neurology, 1(4), 239-50. https://doi.org/10.1002/acn3.48
Benoit, R. M., Frey, D., Hilbert, M., Kevenaar, J. T., Wieser, M. M., Stirnimann, C. U., McMillan, D., Ceska, T., Lebon, F., Jaussi, R., Steinmetz, M. O., Schertler, G. F. X., Hoogenraad, C. C., Capitani, G., & Kammerer, R. A. (2014). Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A. Nature, 505(7481), 108-111. https://doi.org/10.1038/nature12732
Jaarsma, D., van den Berg, R., Wulf, P. S., van Erp, S., Keijzer, N., Schlager, M. A., de Graaff, E., De Zeeuw, C. I., Pasterkamp, R. J., Akhmanova, A., & Hoogenraad, C. C. (2014). A role for Bicaudal-D2 in radial cerebellar granule cell migration. Nature Communications [E], 5, 3411. https://doi.org/10.1038/ncomms4411
Yau, K. W., van Beuningen, S. F. B., Cunha-Ferreira, I., Cloin, B. M. C., van Battum, E. Y., Will, L., Schätzle, P., Tas, R. P., van Krugten, J., Katrukha, E. A., Jiang, K., Wulf, P. S., Mikhaylova, M., Harterink, M., Pasterkamp, R. J., Akhmanova, A., Kapitein, L. C., & Hoogenraad, C. C. (2014). Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development. Neuron, 82(5), 1058-73. https://doi.org/10.1016/j.neuron.2014.04.019
Boekhoorn, K., van Dis, V., Goedknegt, E., Sobel, A., Lucassen, P. J., & Hoogenraad, C. C. (2014). The microtubule destabilizing protein stathmin controls the transition from dividing neuronal precursors to postmitotic neurons during adult hippocampal neurogenesis. Developmental Neurobiology, 74(12), 1226-42. https://doi.org/10.1002/dneu.22200
Van Battum, E. Y., Gunput, R-A. F., Lemstra, S., Groen, E. J. N., Yu, K. L., Adolfs, Y., Zhou, Y., Hoogenraad, C. C., Yoshida, Y., Schachner, M., Akhmanova, A., & Pasterkamp, R. J. (2014). The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections. Nature Communications [E], 5, [4317]. https://doi.org/10.1038/ncomms5317
Adrian, M., Kusters, R., Wierenga, C. J., Storm, C., Hoogenraad, C. C., & Kapitein, L. C. (2014). Barriers in the brain: resolving dendritic spine morphology and compartmentalization. Frontiers in Neuroanatomy, 8, 142. https://doi.org/10.3389/fnana.2014.00142
Hoogenraad, C., & Wierenga, C. (2014). Neurons, Overview. In M. J. Aminoff, & R. B. Daroff (Eds.), Encyclopedia of the Neurological Sciences (2 ed., Vol. 3, pp. 456-458). Academic Press Inc..
van Coevorden - Hameete, M., de Graaff, E., Titulaer, M. J., Hoogenraad, C., & Sillevis Smitt, P. A. (2014). Molecular and celllar mechanisms underlying anti-neuronal antibody mediated disorders of the central nervous system. Autoimmunity Reviews, 13(3), 299-312. https://doi.org/10.1016/j.autrev.2013.10.016
Schwenk, B. M., Lang, C. M., Hogl, S., Tahirovic, S., Orozco, D., Rentzsch, K., Lichtenthaler, S. F., Hoogenraad, C., Capell, A., Haass, C., & Edbauer, D. (2014). The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes. EMBO Journal, 33(5), 450-467. https://doi.org/10.1002/embj.201385857
Schlager, M. A., Serra-Marquez, A., Grigoriev, I., Gumy, L., Estevez da Silva, M., Wulf, P., Akhmanova, A., & Hoogenraad, C. (2014). Bicaudal d family adaptor proteins control the velocity of Dynein-based movements. Cell Reports [E], 8(5), 1248-1256. https://doi.org/10.1016/j.celrep.2014.07.052
Maeder, C. I., Shen, K., & Hoogenraad, C. (2014). Axon and dendritic trafficking. Current Opinion in Neurobiology, 27, 165-170. https://doi.org/10.1016/j.conb.2014.03.015
Jiang, K., Hua, S., Mohan, R., Grigoriev, I., Yau, K. W., Liu, Q., Katrukha, E. A., Altelaar, A. F. M., Heck, A. J. R., Hoogenraad, C. C., & Akhmanova, A. (2014). Microtubule minus-end stabilization by polymerization-driven CAMSAP deposition. Developmental Cell, 28(3), 295-309. https://doi.org/10.1016/j.devcel.2014.01.001
Gumy, L., Katrukha, E., Kapitein, L., & Hoogenraad, C. (2014). New insights into mRNA trafficking in axons. Developmental Neurobiology, 74(3), 233-244. https://doi.org/10.1002/dneu.22121
Geiger, J. C., Lipka, J., Hoyer, S., Schlager, M. A., Wulf, P., Weinges, S., Demmers, J., & Hoogenraad, C. (2014). The GRIP1/14-3-3 pathway coordinates cargo trafficking and dendrite development. Developmental Cell, 28(4), 381-393. https://doi.org/10.1016/j.devcel.2014.01.018
Other output
Kevenaar, J., Bianchi, S., van Spronsen, M., Olieric, N., Lipka, J., Mikhaylova, M., Rietman, L., Wulf, P., Beier, A., Harschnitz, O., Geijsen, N., Kapitein, L., de Graaff, E., Pasterkamp, R. J., Akhmanova, A., Steinmetz, M. O., & Hoogenraad, C. (2014). Goldberg-Shprintzen syndrome protein KBP controls kinesin activity to regulate vesicle trafficking and neuronal development. Poster session presented at Gordon Conference: "Cell Biology of the Neuron" 2014, Waterville Valley, United States.
Franker, M., Kapitein, L., & Hoogenraad, C. (2014). Unraveling the regulatory mechanisms that govrn KIF17 transport in vivo. Poster session presented at Dutch Biophysics meeting 2014, Netherlands.
van Riel, H., Doodhi, H., Kevenaar, J., van der Vaart, B., Grigoriev, I., Bouchet, B., Olieric, N., Bianchi, S., Steinmetz, M. O., Hoogenraad, C., & Akhmanova, A. (2014). Microtubule growth inhition by kinesin-4 family members KIF21A and KIF21B. Poster session presented at EMBO Conference: Microtubules: Structure, Regulation and Functions, Heidelberg, Germany.
Kevenaar, J., Bianchi, S., van Spronsen, M., Olieric, N., Lipka, J., Mikhaylova, M., Rietman, L., Wulf, P., Beier, A., Harschnitz, O., Geijsen, N., Kapitein, L., de Graaff, E., Pasterkamp, R. J., Akhmanova, A., Steinmetz, M. O., & Hoogenraad, C. (2014). Goldberg-Shprintzen syndrome protein KBP controls kinesin activity to regulate vesicle trafficking and neuronal development.
2013
Scholarly publications
Kapitein, L. C., van Bergeijk, P., Lipka, J., Keijzer, N., Wulf, P. S., Katrukha, E. A., Akhmanova, A., & Hoogenraad, C. C. (2013). Myosin-V opposes microtubule-based cargo transport and drives directional motility on cortical actin. Current Biology, 23(9), 828-34. https://doi.org/10.1016/j.cub.2013.03.068
Spangler, S. A., Schmitz, S. K., Kevenaar, J. T., de Graaff, E., de Wit, H., Demmers, J., Toonen, R. F. G., & Hoogenraad, C. C. (2013). Liprin-alpha2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission. Journal of Cell Biology, 201(6), 915-928.
Timmermans, W., Xiong, H., Hoogenraad, C. C., & Krugers, H. J. (2013). Stress and excitatory synapses: from health to disease. Neuroscience, 248, 626-636.
Gumy, L. F., & Hoogenraad, C. C. (2013). Off the rails: axonal cargoes on the road to nowhere. EMBO Journal, 32(10), 1345-1347.
van Spronsen, M., Mikhaylova, M., Lipka, J., Schlager, M. A., van den Heuvel, D. J., Kuijpers, M., Wulf, P. S., Keijzer, N., Demmers, J., Kapitein, L. C., Jaarsma, D., Gerritsen, H., Akhmanova, A., & Hoogenraad, C. C. (2013). TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites. Neuron, 77(3), 485-502. https://doi.org/10.1016/j.neuron.2012.11.027
Kuijpers, M., Yu, K. L., Teuling, E., Akhmanova, A. S., Jaarsma, D., & Hoogenraad, C. C. (2013). The ALS8 protein VAPB interacts with the ER-Gogi recycling protein YIF1A and regulates membrane delivery into dendrites. EMBO Journal, 32(14), 2056-2072.
Lipka, J. E., Kuijpers, M., Jaworski, J., & Hoogenraad, C. C. (2013). Mutations in cytopalsmic dynein and its regulators cause malformations of cortical development and neurodegenerative diseases. Biochemical Society Transactions, 41(6), 1605-1612.
Kapitein, L. C., van Bergeijk, P. M., Lipka, J. E., Keijzer, N., Wulf, P. S., Katrukha, Y., Akhmanova, A. S., & Hoogenraad, C. C. (2013). Myosin-V opposes microtuble-based cargo transport and drives directional motility on cortical actin. Current Biology, 23(9), 828-834.
Gumy, L. F., Chew, D. J., Tortosa, E., Katrukha, Y., Kapitein, L. C., Tolkovsky, A. M., Hoogenraad, C. C., & Fawcett, J. W. (2013). The kinesin-2 family member KIF3C regulates microtubule dynamics and is required for axon growth and regeneration. Journal of Neuroscience, 33(28), 11329-11345.
van der Vaart, B., van Riel, W. E., Doodhi, H., Kevenaar, J. T., Katrukha, E. A., Gumy, L., Bouchet, B. P., Grigoriev, I., Spangler, S. A., Yu, K. L., Wulf, P. S., Wu, J., Lansbergen, G., van Battum, E. Y., Pasterkamp, R. J., Mimori-Kiyosue, Y., Demmers, J., Olieric, N., Maly, I. V., ... Akhmanova, A. (2013). CFEOM1-Associated Kinesin KIF21A Is a Cortical Microtubule Growth Inhibitor. Developmental Cell, 27(2), 145-160. https://doi.org/10.1016/j.devcel.2013.09.010
van Spronsen, C. S. A. M., van Battum, E. Y., Kuijpers, M., Vangoor, V. R., rietman, M. L., Pothof, J., Gumy, L. F., van IJcken, W., Akhmanova, A. S., Pasterkamp, R. J., & Hoogenraad, C. C. (2013). Developmental and Activity-Dependent miRNA Expression Profiling in Primary Hippocampal Neuron Cultures. PLoS One, 8(10), e74907. http://www.ncbi.nlm.nih.gov/pubmed/24098357
Maat, P., de Graaff, E., Beveren, N. M., Hulsenboom, E., Verdijk, R. M., Koorengevel, K., van Duijn, M., Hooijkaas, H., Hoogenraad, C. C., & Sillevis Smitt, P. A. (2013). Psychiatric phenomena as initial manifestation of encephalitis by anti-NMDAR antibodies. Acta Neuropsychiatrica, 25(3), 128-136.
Prota, E. A., Magiera, M. M., Kuijpers, M., Bargsten, K., Frey, D., Wieser, M. M., Jaussi, R., Hoogenraad, C. C., Kammerer, R. A., Janke, C., & Steinmetz, M. O. (2013). Structural basis of tubulin tyrosination by tubulin tyrosine ligase. Journal of Cell Biology, 200(3), 259-270.
Harterink, M., & Hoogenraad, C. C. (2013). Slide to the left and slide to the right: motor coordination in neurons. Developmental Cell, 26(4), 326-328.
Other output
Kevenaar, J. T., Schmitz, S. K., Spangler, S. A., Jaarsma, D., de Graaff, E., Toonen, R. F., & Hoogenraad, C. C. (2013). Liprin-a2 regulates presynaptic plasticity by organizing active zone composition. Poster session presented at ENCODS, Bordeaux, France.
Harterink, M., de Haan, B., & Hoogenraad, C. C. (2013). Neuronal microtubule organization in C. Elegans.. Poster session presented at The microtubule cytoskeleton in development and disease, Barcelona, Spain.
Estevez da Silva, M., Kapitein, L. C., Adrian, M., Wierenga, C. J., & Hoogenraad, C. C. (2013). Controlled delivery of AMPA receptors-containing recycling endosomes to excitatory synapsis.. Poster session presented at Gordon Research Conference-Excitatory Synapsis & Brain Function, Les Diablerets, Switzerland.
van Bergeijk, P., Adrian, M., Hoogenraad, C. C., & Kapitein, L. C. (2013). Optical control of Intracellular Transport. Poster session presented at american Society of Cell Biology (ASCB) Annual meeting.
Estevez da Silva, M., Kapitein, L. C., Adrian, M., Wierenga, C. J., & Hoogenraad, C. C. (2013). Controlled delivery of AMPA receptors-containing recycling endosomes to excitatory synapsis. Poster session presented at 20th Annual ONWAR PhD meeting, Woudschoten, the Netherlands.
Estevez da Silva, M., Kapitein, L. C., Adrian, M., Wierenga, C. J., & Hoogenraad, C. C. (2013). Controlled delivery of AMPA receptors-containing recycling endosomes to excitatory synapses. Poster session presented at Gordon Research Seminar-Excitatory Synapsis & Brain Funtion, Les Diablerets, Switzerland.
Pereira Frias, C. S., Hoogenraad, C. C., & Wierenga, C. J. (2013). Two-photon microscopy of dunamic changes in inhibitory axons induced by Sema4D. Poster session presented at Dutch meeting on Molecular and Cellular Biophysics, Veldhoven, The Netherlands.
Kevenaar, J. T., Schmitz, S. K., Spangler, S. A., Jaarsma, D., de Graaff, E., Toonen, R. F., & Hoogenraad, C. C. (2013). Liprin-a2 regulates presynaptic plasticity by organizing active zone composition. Poster session presented at Gordon Research Conference Excitatory synapses and brain function, les Diablerets, Switzerland.
Cloin, B. M. C., Katrukha, Y., Mikhaylova, M., Hoogenraad, C. C., & Kapitein, L. C. (2013). Super-resolution of the cytoskeleton to understand polarized transport in neurons. Poster session presented at STW Nano dag, Utrecht, The Netherlands.
Yau, K. W., van Beuningen, S. F. B., Cloin, B. M. C., Jiang, K., Katrukha, Y., Harterink, M., Wulf, P. S., Akhmanova, A. S., Kapitein, L. C., & Hoogenraad, C. C. (2013). Microtubule minus-end binding protein CAMSAP2 controls specification and dendrite development. Poster session presented at The 5th EMBO meeting, Amsterdam, The Netherlands.
van Riel, W. E., van der Vaart, B., Doodhi, H., Kevenaar, J. T., Grigoriev, I. S., Bouchet, B. P. J., Hoogenraad, C. C., & Akhmanova, A. S. (2013). Congenital Fibrosis of the Extraocular Muscles type 1 (CFEOM1)-associated kinesin KIF21A is a cortical microtubule growth inhibitor.. Poster session presented at BioMed Conferences: The microtubule cytoskeleton in development and disease., Barcelona, Spain.
Franker, M. A. M. L., Kapitein, L. C., & Hoogenraad, C. C. (2013). Kinesin-1 and kinesin-2 motor proteins are regulated by different mechanisms in living cells.. Poster session presented at Molecular and Cellular Biophysics, Veldhoven, The Netherlands.
Pereira Frias, C. S., Hoogenraad, C. C., & Wierenga, C. J. (2013). Two-photon microscopy of dynamic changes in inhibitory axonal boutons induced by Sema4D. Poster session presented at ESN-FENS Conference "The Neurobiology of Synapsis and their Dysfunction", Stresa, Italy.
Kevenaar, J. T., Bianchi, S., van Spronsen, M., Olieric, N., Lipka, J. E., Mikhaylova, M., Rietman, L. M., Kapitein, L. C., de Graaff, E., Keijzer, N., Wulf, P. S., Pasterkamp, J. R., Steinmetz, M. O., Hoogenraad, C. C., & Akhmanova, A. S. (2013). Misregulation of KIF1A-mediated synaptic vesicle transport underlies Goldberg-Shprintzen syndrome. Poster session presented at Annual PhD ONWAR meeting, Zeist, The Netherlands.
Mikhaylova, M., Katrukha, Y., Brakel, H. X., van Bergen en Henegouwen, P. M. P., Akhmanova, A. S., Hoogenraad, C. C., & Kapitein, L. C. (2013). Inducible targeting of cytoplasmic quantum dots.. Poster session presented at Dutch meeting on Molecular and Cellular Biophysics, Veldhoven, The Netherlands.
Harterink, M., de Haan, B., Yau, K. W., van den Heuvel, S., & Hoogenraad, C. C. (2013). Neuronal microtubule organization in C. Elegans.. Poster session presented at 19th International C. elegans meeting, Los Angeles, UCLA.
Gumy, L. F., Chew, D. J., Tortosa Binacua, E., Katrukha, Y., Kapitein, L. C., Tolkovsky, A. M., Hoogenraad, C. C., & Fawcett, J. W. (2013). The kinesin-2 family member KIF3C regulates microtubule dynamics and is required for axon growth and regeneration.. Poster session presented at Symposia: Cell biology and pathology of axons, Lake Tahoe, Ca, USA.
2012
Scholarly publications
Zhou, M., Hoogenraad, C. C., Joels, M., & Krugers, H. J. (2012). Combined β-adrenergic and corticosteroid receptor activation regulates AMPA receptor function in hippocampal neurons. Journal of Psychopharmacology, 26(4), 516-524. http://www.ncbi.nlm.nih.gov/pubmed/21965192
Zhou, M., Hoogenraad, C. C., Joëls - de Kloet, M., & Krugers, H. J. (2012). Combined ß-adrenergic and corticosteroid receptor activation regulates AMPA receptor function in hippocampal neurons. Journal of Psychopharmacology, 26(4), 516-524.
van der Vaart, B., Franker, M. A., Kuijpers, M., Hua, S., Bouchet, B. P. J., Jiang, K., Grigoriev, I. S., Hoogenraad, C. C., & Akhmanova, A. S. (2012). Microtubule plus-end tracking proteins SLAIN1/2 and ch-TOG promote axonal development. Journal of Neuroscience, 32(42), 14722-14728. https://doi.org/10.1523/JNEUROSCI.1240-12.2012
de Graaff, E., Maat, P., Hulsenboom, E., van den Berg, R., van den Bent, M., Demmers, J., Lugtenburg, P. J., Hoogenraad, C. C., & Sillevis Smitt, P. (2012). Identification of delta/notch-like epidermal growth factor-related receptor as the Tr antigen inparaneoplastic cerebellar degeneration. Annals of Neurology, 71(6), 815-824. https://doi.org/10.1002/ana.23550
Splinter, D., Razafsky, D. S., Schlager, M. A., Serra-Marques, A., Grigoriev, I. S., Demmers, J., Keijzer, N., Jiang, K., Poser, I., Hyman, A. A., Hoogenraad, C. C., King, S. J., & Akhmanova, A. S. (2012). BICD2, dynactin, and LIS1 cooperate in reulating dynein recruitment to cellular structures. Molecular and Cellular Biology, 23(21), 4226-4241.
van den Berg, R., & Hoogenraad, C. C. (2012). Molecular motors in cargo trafficking and synapse assembly. Advances in Experimental Medicine and Biology, 970, 173-196.
Other output
Boekhoorn, K., van Dis, V., Goedknegt, E., Lucassen, P. J., & Hoogenraad, C. C. (2012). The microtubule de-stabilizing protein stathmin is invovled in adult hippocampal neurogenesis. Abstract from Regulation of adult neurogenesis: from epigenetics to behavior, Barcelona, Spain.
Kevenaar, J. T., Schmitz, S. K., Jaarsma, D., de Graaff, E., Toonen, R. F. G., & Hoogenraad, C. C. (2012). Liprin-α2 regulates presynaptic plasticity by organizaing active zone composition. Abstract from Federation of European Neuroscience Societies Forum of Neuroscience, Barcelona.
Kuijpers, M., Yu, K. L., Teuling, E., Akhmanova, A. S., Jaarsma, D., & Hoogenraad, C. C. (2012). The ALS protein VAPB interacts with the ER-Golgi recycling protein YIF1A and regulates membrane delivery into dendrites. Poster session presented at World Molecular Imaging Congress & European Molecular Imaging Meeting, Waterville Valey, NH, USA.
Hoogenraad, C. C. (2012). Cellulaire dynamica – beweging in ons brein. Utrecht University.
https://dspace.library.uu.nl/bitstream/handle/1874/234360/Casper%2520oratie%2520final%2520version.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/234360/Casper%2520oratie%2520final%2520version.pdf?sequence=1
Mikhaylova, M., Reddy, P. P., Hradsky, J., Kapitein, L. C., Hoogenraad, C. C., & Kreutz, M. R. (2012). Calcium dependent regulation of actin dynamcis in spines via caldendrin and cortactin. Abstract from 8th FENS Forum of Neuroscience, Barcelona, Spain.
van den Berg, R., Katrukha, Y., Cloin, B. M. C., Mikhaylova, M., Hoogenraad, C. C., & Kapitein, L. C. (2012). From Tip to Tail; Superresolution imaging of cytoskeleton proteins. Poster session presented at The Dutch meeting on Molecular and Cellular Biophysics, Veldhoven.
Kuijpers, M., Yu, K. L., Teuling, E., Akhmanova, A. S., Jaarsma, D., & Hoogenraad, C. C. (2012). The ALS protein VAPB interacts with the ER-Golgi recycling protein YIF1A and regulates membrane delivery into dendrites. Poster session presented at The Dutch meeing on Molecular and Cellular Biophysics, Veldhoven.
Lipka, J. E., van Spronsen, C. S. A. M., Franker, A. M., Estevez da Silva, M., Kapitein, L. C., & Hoogenraad, C. C. (2012). Kinesin-1 and dynein motors drive polarized mitochondria transport in neurons. Poster session presented at The Dutch meeting on Molecular and Cellular Biophysics, Veldhoven.
Boekhoorn, K., van Dis, V., Goedknegt, E., Lucassen, P. J., & Hoogenraad, C. C. (2012). The microtubule de-stabilizing protein stathmin is invovled in adult hippocampal neurogenesis. Poster session presented at 8th FENS Forum of Neuroscience, Barcelona, Spain.
Kuijpers, M., Yu, K. L., Teuling, E., Akhmanova, A. S., Jaarsma, D., & Hoogenraad, C. C. (2012). The ALS protein VAPB interacts with the ER-Golgi recycling protein YIF1A and regulates membrane delivery into dendrites. Abstract from The Dutch meeting on Molecular and Cellular Biophysics, Veldhoven.
Kuijpers, M., Yu, K. L., Teuling, E., Akhmanova, A. S., Jaarsma, D., & Hoogenraad, C. C. (2012). The ALS protein VAPB interacts with the ER-Golgi recycling protein YIF1A and regulates membrane delivery into dendrites. Abstract from World Molecular Imaging Congress & European Molecular Imaging Meeting, Waterville Valey, NH, USA.
Boekhoorn, K., van Dis, V., Goedknegt, E., Lucassen, P. J., & Hoogenraad, C. C. (2012). The microtubule de-stabilizing protein stathmin is invovled in adult hippocampal neurogenesis. Abstract from 8th FENS Forum of Neuroscience, Barcelona, Spain.
Gumy, L. F., Chew, D., Katrukha, Y., Kapitein, L. C., Tolkovsky, A. M., Hoogenraad, C. C., & Fawcett, J. W. (2012). The motor protein Kif3c regulates microtubule dynamics and is required for axon growth and regeneration. Abstract from Gordon Research Conference "Cell Biology of the Neuron", Waterville, NH, USA.
van den Berg, R., Katrukha, Y., Cloin, B. M. C., Mikhaylova, M., Hoogenraad, C. C., & Kapitein, L. C. (2012). From Tip to Tail; Superresolution imaging of cytoskeleton proteins. Abstract from The Dutch meeting on Molecular and Cellular Biophysics, Veldhoven.
Kevenaar, J. T., Schmitz, S. K., Jaarsma, D., de Graaff, E., Toonen, R. F. G., & Hoogenraad, C. C. (2012). Liprin-α2 regulates presynaptic plasticity by organizaing active zone composition. Poster session presented at Federation of European Neuroscience Societies Forum of Neuroscience, Barcelona.
Lipka, J. E., van Spronsen, C. S. A. M., Franker, A. M., Estevez da Silva, M., Kapitein, L. C., & Hoogenraad, C. C. (2012). Kinesin-1 and dynein motors drive polarized mitochondria transport in neurons. Abstract from The Dutch meeting on Molecular and Cellular Biophysics, Veldhoven.
Mikhaylova, M., Reddy, P. P., Hradsky, J., Kapitein, L. C., Hoogenraad, C. C., & Kreutz, M. R. (2012). Calcium dependent regulation of actin dynamcis in spines via caldendrin and cortactin. Poster session presented at 8th FENS Forum of Neuroscience, Barcelona, Spain.
Boekhoorn, K., van Dis, V., Goedknegt, E., Lucassen, P. J., & Hoogenraad, C. C. (2012). The microtubule de-stabilizing protein stathmin is invovled in adult hippocampal neurogenesis. Poster session presented at Regulation of adult neurogenesis: from epigenetics to behavior, Barcelona, Spain.
Boekhoorn, K., van Dis, V., Goedknegt, E., Lucassen, P. J., & Hoogenraad, C. C. (2012). The microtubule de-stabilizing protein stathmin is invovled in adult hippocampal neurogenesis. Poster session presented at Dutch meeting on Molecular and Cellular Biophysics, Veldhoven.
Lipka, J. E., van Spronsen, C. S. A. M., Franker, M. A. M. L., Estevez da Silva, M., Kapitein, L. C., & Hoogenraad, C. C. (2012). Kinesin-1 and dynein motors drive polarized mitochondria transport in neurons. Poster session presented at 8th FENS Forum of Neuroscience, Barcelona, Spain.
2011
Scholarly publications
Spangler, S. A., Jaarsma, D., de Graaff, E., Wulf, P. S., Akhmanova, A. S., & Hoogenraad, C. C. (2011). Differential expression of liprin-alpha proteins in the brain suggests functional diversification. Journal of Comparative Neurology, 519(15), 3040-3060.
Kuijpers, M., & Hoogenraad, C. C. (2011). Centrosomes, microtubules and neuronal development. Molecular and Cellular Neuroscience, 48(4), 349-358. https://doi.org/10.1016/j.mcn.2011.05.004
Bralten, L. B., Nouwens, S., Kockx, C., Erdem, L., Hoogenraad, C. C., Kros, J. M., Moorhouse, M. J., Sillevis Smitt, P. A., van der Spek, P., van IJcken, W., Stubbs, A., & French, P. J. (2011). Absence of common somatic alterations in genes on 1p and 19q in oligodendrogiomas. PLoS One, 6(7), e22000.
van der Vaart, B., Manatschal, C., Grigoriev, I. S., Olieric, V., Gouveia, S. M., Bjelic, S., Demmers, J., Vorobjev, I., Hoogenraad, C. C., Steinmetz, M. O., & Akhmanova, A. S. (2011). SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase. Current Biology, 21(11), 967-974.
Wei, Z., Zheng, S., Spangler, S. A., Yu, C., Hoogenraad, C. C., & Zhang, M. (2011). Liprin-mediated large signaling complex organization revealed by the liprin-alpha/CASK and liprin-alpha/liprin-beta complex structures. Molecular Cell, 43(4), 586-598. https://www.sciencedirect.com/science/article/pii/S1097276511005788?via%3Dihub
Swiech, L., Blazejczyk, M., Urbanska, M., Pietruszka, P., Dortland, B. R., Malik, A. R., Wulf, P. S., Hoogenraad, C. C., & Jaworski, J. (2011). CLIP-170 and IQGAP1 cooperatively regulate dendrite morphology. Journal of Neuroscience, 31(12), 4555-4568.
Kapitein, L. C., Yau, K. W., Gouveia, S. M., van der Zwan, W. A., Wulf, P. S., Keijzer, N., Demmers, J., Jaworski, J., Akhmanova, A. S., & Hoogenraad, C. C. (2011). NMDA receptor activation suppresses microtubule growth and spine entry. Journal of Neuroscience, 31(22), 8194-8209.
Hossaini, M., Cano, S. C., van Dis, V., Haasdijk, E. D., Hoogenraad, C. C., Holstege, J. C., & Jaarsma, D. (2011). Spinal inhibitory interneuron pathology follows motor neuron degeneration independent of glial mutant superoxide dismutase 1 expression in SOD1-ALS mice. Journal of Neuropathology and Experimental Neurology, 70(8), 662-677.
Borgesius, N. Z., van Woerden, G. M., Buitendijk, G. H., Keijzer, N., Jaarsma, D., Hoogenraad, C. C., & Elgersma, Y. (2011). {beta}CaMKII plays a nonenzymatic role in hippocampal synaptic plasticity and learning by targeting {alpha}CaMKII to synapses. Journal of Neuroscience, 31(28), 10141-10148.
Grigoriev, I., Yu, K. L., Martinez Sanchez, E., Serra-Marquez, A., Smal, I., Meijering, E., Peränen, J., Pasterkamp, R. J., van der Sluijs, P., Hoogenraad, C. C., & Akhmanova, A. S. (2011). Rab6, Rab8, and MICAL3 cooperate in controlling docking and fusion of exocytotic carriers. Current Biology, 21(11), 967-974. http://www.ncbi.nlm.nih.gov/pubmed/21596566
van der Sluijs, P., & Hoogenraad, C. C. (2011). New insights in endosomal dynamics and AMPA receptor trafficking. Seminars in cell & developmental biology, 22(5), 499-505.
Hayashi, K., Suzuki, A., Hirai, S., Kurihara, Y., Hoogenraad, C. C., & Ohno, S. (2011). Maintenance of dendritic spine morphology by partitioning-defective 1b through regulation of microtubule growth. Journal of Neuroscience, 31(34), 12094-12103.
Other output
de Graaff, E., Maat, P., Hulsenboom, E., van den Berg, R., van den Bent, M., Demmers, J., & Hoogenraad, C. C. (2011). Identifying the anti-TR antigen in paraneoplastic cerbellar degeneration. Abstract from American Society for Cell Biology Annual Meeting 2011, Denver.
de Graaff, E., Maat, P., Hulsenboom, E., van den Berg, R., van den Bent, M., Demmers, J., & Hoogenraad, C. C. (2011). Identifying the anti-TR antigen in paraneoplastic cerbellar degeneration. Poster session presented at American Society for Cell Biology Annual Meeting 2011, Denver.
Yu, K. L., Grigoriev, I. S., Martinez Sanchez, E., Serra-Marquez, A., Peranen, J., Pasterkamp, R. J., van der Sluijs, P., Hoogenraad, C. C., & Akhmanova, A. S. (2011). Rab6, Rab8, and MICAL3 cooperate in controlling docking and fusion of exocytotic carriers. Abstract from American Society for Cell Biology Annual Meeting 2011, Denver.
Yu, K. L., Grigoriev, I. S., Martinez Sanchez, E., Serra-Marquez, A., Peranen, J., Pasterkamp, R. J., van der Sluijs, P., Hoogenraad, C. C., & Akhmanova, A. S. (2011). Rab6, Rab8, and MICAL3 cooperate in controlling docking and fusion of exocytotic carriers. Poster session presented at American Society for Cell Biology Annual Meeting 2011, Denver.
2010
Scholarly publications
Stiess, M., Maghelli, N., Kapitein, L. C., Gomis-Rüth, S., Wilsch-Bräuninger, M., Hoogenraad, C. C., Tolić-Nørrelykke, I. M., & Bradke, F. (2010). Axon extension occurs independently of centrosomal microtubule nucleation. Science, 327(5966), 704-7. https://doi.org/10.1126/science.1182179
Kapitein, L. C., Schlager, M. A., Kuijpers, M., Wulf, P. S., van Spronsen, M., MacKintosh, F. C., & Hoogenraad, C. C. (2010). Mixed microtubules steer dynein-driven cargo transport into dendrites. Current Biology, 20(4), 290-9. https://doi.org/10.1016/j.cub.2009.12.052
Kapitein, L. C., Schlager, M. A., van der Zwan, W. A., Wulf, P. S., Keijzer, N., & Hoogenraad, C. C. (2010). Probing intracellular motor protein activity using an inducible cargo trafficking assay. Biophysical Journal, 99(7), 2143-52. https://doi.org/10.1016/j.bpj.2010.07.055
Hoogenraad, C. C., Popa, I. L., Futai, K., Martinez Sanchez, E., Wulf, P. S., van Vlijmen, T., Dortland, B., Oorschot, V. M. J., Govers, R., Monti, M., Heck, A. J. R., Sheng, M., Klumperman, J., Rehmann, H., Jaarsma, D., Kapitein, L. C., & van der Sluijs, P. (2010). Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes. PloS Biology [E], 8(1), e1000283. http://www.ncbi.nlm.nih.gov/pubmed/20098723
Splinter, D., Tanenbaum, M. E., Lindqvist, A., Jaarsma, D., Flotho, A., Yu, K. L., Grigoriev, I., Engelsma, D., Haasdijk, E. D., Keijzer, N., Demmers, J., Fornerod, M., Melchior, F., Hoogenraad, C. C., Medema, R. H., & Akhmanova, A. S. (2010). Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry. PloS Biology [E], 8(4), e1000350. http://www.ncbi.nlm.nih.gov/pubmed/20386726
2009
Scholarly publications
Jaworski, J., Kapitein, L. C., Gouveia, S. M., Dortland, B. R., Wulf, P. S., Grigoriev, I., Camera, P., Spangler, S. A., Di Stefano, P., Demmers, J., Krugers, H., Defilippi, P., Akhmanova, A., & Hoogenraad, C. C. (2009). Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity. Neuron, 61(1), 85-100. https://doi.org/10.1016/j.neuron.2008.11.013
2008
Scholarly publications
Jaarsma, D., Teuling, E., Haasdijk, E. D., De Zeeuw, C. I., & Hoogenraad, C. C. (2008). Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice. Journal of Neuroscience, 28(9), 2075-88. https://doi.org/10.1523/JNEUROSCI.5258-07.2008
van Vlijmen, T., Vleugel, M. M., Evers, M., Mohammed, S., Wulf, P. S., Heck, A. J. R., Hoogenraad, C. C., & van der Sluijs, P. (2008). A unique residue in rab3c determines the interaction with novel binding protein Zwint-1. The FEBS journal, 582, 2838-2842.
2007
Scholarly publications
Sheng, M., & Hoogenraad, C. C. (2007). The postsynaptic architecture of excitatory synapses: a more quantitative view. Annual Review of Biochemistry, 76, 823-47. https://doi.org/10.1146/annurev.biochem.76.060805.160029
2005
Scholarly publications
Dunah, A. W., Hueske, E., Wyszynski, M., Hoogenraad, C. C., Jaworski, J., Pak, D. T., Simonetta, A., Liu, G., & Sheng, M. (2005). LAR receptor protein tyrosine phosphatases in the development and maintenance of excitatory synapses. Nature Neuroscience, 8(4), 458-67. https://doi.org/10.1038/nn1416
Akhmanova, A., & Hoogenraad, C. C. (2005). Microtubule plus-end-tracking proteins: mechanisms and functions. Current Opinion in Cell Biology, 17(1), 47-54. https://doi.org/10.1016/j.ceb.2004.11.001
Akhmanova, A. S., Mausset-Bonnefont, A. L., van Cappellen, W., Keijzer, N., Hoogenraad, C. C., Stepanova, T., Drabek, K., van Wees, J. D., Mommaas, M., Onderwater, J., van der Meulen, H., Tanenbaum, M. E., Medema, R. H., Hoogerbrugge, J. W., Vreeburg, J., Uringa, E. J., Grootegoed, J. A., Grosveld, F., & Galjart, N. (2005). The microtubule plus-end-tracking protein CLIP-170 associates with the spermatid manchette and is essential for spermatogenesis. Genes and Development, 19(20), 2501-15.
2004
Scholarly publications
Lansbergen, G., Komarova, Y., Modesti, M., Wyman, C., Hoogenraad, C. C., Goodson, H. V., Lemaitre, R. P., Drechsel, D. N., van Munster, E., Gadella, T. W. J., Grosveld, F., Galjart, N., Borisy, G. G., & Akhmanova, A. (2004). Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization. Journal of Cell Biology, 166(7), 1003-14. https://doi.org/10.1083/jcb.200402082
Hoogenraad, C. C., Akhmanova, A., Galjart, N., & De Zeeuw, C. I. (2004). LIMK1 and CLIP-115: linking cytoskeletal defects to Williams syndrome. BioEssays, 26(2), 141-50. https://doi.org/10.1002/bies.10402
2003
Scholarly publications
Hoogenraad, C. C., Wulf, P., Schiefermeier, N., Stepanova, T., Galjart, N., Small, J. V., Grosveld, F., de Zeeuw, C. I., & Akhmanova, A. (2003). Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport. EMBO Journal, 22(22), 6004-15. https://doi.org/10.1093/emboj/cdg592
De Zeeuw, C. I., Chorev, E., Devor, A., Manor, Y., Van Der Giessen, R. S., De Jeu, M. T., Hoogenraad, C. C., Bijman, J., Ruigrok, T. J. H., French, P., Jaarsma, D., Kistler, W. M., Meier, C., Petrasch-Parwez, E., Dermietzel, R., Sohl, G., Gueldenagel, M., Willecke, K., & Yarom, Y. (2003). Deformation of network connectivity in the inferior olive of connexin 36-deficient mice is compensated by morphological and electrophysiological changes at the single neuron level. Journal of Neuroscience, 23(11), 4700-11.
Hoogenraad, C. C., & Sheng, M. (2003). The return of the exocyst. Nature Cell Biology, 5(6), 493-5. https://doi.org/10.1038/ncb0603-493
Stepanova, T., Slemmer, J., Hoogenraad, C. C., Lansbergen, G., Dortland, B., De Zeeuw, C. I., Grosveld, F., van Cappellen, G., Akhmanova, A., & Galjart, N. (2003). Visualization of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein). Journal of Neuroscience, 23(7), 2655-64.
2002
Scholarly publications
Matanis, T., Akhmanova, A., Wulf, P., Del Nery, E., Weide, T., Stepanova, T., Galjart, N., Grosveld, F., Goud, B., De Zeeuw, C. I., Barnekow, A., & Hoogenraad, C. C. (2002). Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex. Nature Cell Biology, 4(12), 986-92. https://doi.org/10.1038/ncb891
Hoogenraad, C. C., Koekkoek, B., Akhmanova, A., Krugers, H., Dortland, B., Miedema, M., van Alphen, A., Kistler, W. M., Jaegle, M., Koutsourakis, M., Van Camp, N., Verhoye, M., van der Linden, A., Kaverina, I., Grosveld, F., De Zeeuw, C. I., & Galjart, N. (2002). Targeted mutation of Cyln2 in the Williams syndrome critical region links CLIP-115 haploinsufficiency to neurodevelopmental abnormalities in mice. Nature Genetics, 32(1), 116-27. https://doi.org/10.1038/ng954
Coquelle, F. M., Caspi, M., Cordelières, F. P., Dompierre, J. P., Dujardin, D. L., Koifman, C., Martin, P., Hoogenraad, C. C., Akhmanova, A., Galjart, N., De Mey, J. R., & Reiner, O. (2002). LIS1, CLIP-170's key to the dynein/dynactin pathway. Molecular and Cellular Biology, 22(9), 3089-102.
2001
Scholarly publications
Akhmanova, A. S., Hoogenraad, C. C., Drabek, K., Stepanova, T., Dortland, B., Verkerk, T., Vermeulen, W., Burgering, B. M. T., de Zeeuw, C. I., Grosveld, F., & Galjart, N. (2001). CLASPs are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fribroblasts. Cell, 104, 923-935.