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Dr. P.J.J. (Paul) Mandigers

Universitair hoofddocent 
Diergeneeskunde
Departement Clinical Sciences
Inwendige Geneeskunde Gezelschapsdieren
Inwendige Geneeskunde Gezelschapsdieren
Prof. dr. H. Jakobgebouw
Yalelaan 108
3584 CM Utrecht

Dr. P.J.J. (Paul) Mandigers

Universitair hoofddocent
Inwendige Geneeskunde Gezelschapsdieren
p.j.j.mandigers@uu.nl
Profiel CV Publicaties Activiteiten Onderzoek Onderwijs Nevenwerkzaamheden Contact
Profiel CV Publicaties Activiteiten Onderzoek Onderwijs Nevenwerkzaamheden Contact
Onderzoeksthema's

Publicaties

2024

Wetenschappelijke publicaties

Plonek, M., Santifort, K. M., Verduijn, D., Stanczyk, E., Bergmann, W., & Mandigers, P. (2024). Cervicothoracic kyphoscoliosis in a Llama cria. Poster session presented at 36th ESVN-ECVN Congress 2024, Porto, Portugal.
Mandigers, P. (2024). Hearing assessment in Pomeranian dogs with and without Chiari-like malformation based on brainstem auditory evoked response wave latencies – a pilot study.. Poster session presented at 36th ESVN-ECVN Congress 2024, Porto, Portugal.
Santifort, K. M., Bellekom, S. R., Carrera, I., & Mandigers, P. (2024). External manual measurement of mandible length to predict the probability of a Pomeranian having syringomyelia.. Poster session presented at 36th ESVN-ECVN Congress 2024, Porto, Portugal.
Mandigers, P., Opmeer, Y., Alf, V., Diane Shelton, G., van Steenbeek, F., Rozendom, C., van Kooten, P., Rutten, VP., Grinwis, G., Hytönen, M. K., Rosati, M., Fieten, H., Lohi, H., Leegwater, P., & Matiasek, K. (2024). Polymyositis in the Dutch Kooikerdog. Abstract from 36th ESVN-ECVN Congress 2024, Porto, Portugal.
Alf, V., Opmeer, Y., Shelton, G. D., Grinwis, G. C. M., Matiasek, K., Rosati, M., & Mandigers, P. J. J. (2024). Pathologic Changes in and Immunophenotyping of Polymyositis in the Dutch Kooiker Dog. Animals, 14(17). https://doi.org/10.3390/ani14172519
Mandigers, P. J. J., Santifort, K. M., Lowrie, M., & Garosi, L. (2024). Canine paroxysmal dyskinesia-a review. Frontiers in Veterinary Science, 11, Article 1441332. https://doi.org/10.3389/fvets.2024.1441332
Gouveia, D., Mandigers, P., & Cherubini, G. B. (2024). Bromide: the good, the bad, and the ugly of the oldest antiseizure medication. Frontiers in Veterinary Science, 11, Article 1433191. https://doi.org/10.3389/fvets.2024.1433191
Santifort, K., Bellekom, S., Carrera, I., & Mandigers, P. (2024). Craniocervical Morphometry in Pomeranians—Part II: Associations with Chiari-like Malformation and Syringomyelia. Animals, 14(13), Article 1859. https://doi.org/10.3390/ani14131859
Santifort, K., Bellekom, S., Carrera, I., & Mandigers, P. (2024). Craniocervical Morphometry in Pomeranians—Part I: Intra-Observer, Interobserver, and Intermodality (CT vs. MRI) Agreement. Animals, 14(13), Article 1854. https://doi.org/10.3390/ani14131854
Opmeer, Y., Alf, V., Shelton, G. D., Grinwis, G., Rosati, M., Fieten, H., Leegwater, P., Matiasek, K., & Mandigers, P. (2024). Immune Mediated Polymyositis In The Dutch Kooiker Dog. 108. Abstract from ICCFGG 2024, Helsinki, Finland.
Limpens, C., Mandigers, P., Leegwater, P., & Fieten, H. (2024). Population and health analysis in the worldwide population of the Dutch Kooikerdog. 106. Abstract from ICCFGG 2024, Helsinki, Finland.
Leegwater, P., Opmeer, Y., van Steenbeek, F., Rozendom, C., van Kooten, P., Rutten, VP., Fieten, H., Hytönen, M. K., Lohi, H., & Mandigers, P. (2024). Polymyositis in Kooiker dogs is associated with a 39 kb deletion upstream the IL21/IL2 genes. 100. Abstract from ICCFGG 2024, Helsinki, Finland.
Jenkins, C., Di Risio, L., Harmas, T., Johnson, J., Schofield, E. C., Kennedy, L., Short, A., Bhatti, S. F., Foster, D., Leegwater, P., Jokinen, T., Packer, R. M. A., Santifort, K. M., Mandigers, P., Volk, H. A., Mellersh, C., Hytönen, M. K., Lohi, H., & Ricketts, S. L. (2024). Idiopathic epilepsy in the Border Collie: identifying common and rare genetic risk factors. 27. Abstract from ICCFGG 2024, Helsinki, Finland.
Harmas, T., Forman, O., Fischer, A., Freyer, J., Matz, M. S., Fukata, M., Fukata, Y., Nessler, J., Volk, H. A., Tipold, A., Mandigers, P., Leegwater, P., Di Risio, L., Ricketts, S. L., Jenkins, C., Jokinen, T., Meervenne, S. V., Minor, K., Leeb, T., ... Lohi, H. (2024). A study of over 15,000 dogs identifies the major locus for canine non-generalized tonic-clonic seizures. 26. Abstract from ICCFGG 2024, Helsinki, Finland.
Evans, J., Cook, S., Hugen, S., Hayward, J. J., Famula, T. R., McNiel, E., Oberbauer, A., Leegwater, P., Ostrander, E. A., & Mandigers, P. (2024). Bayesian analysis and selection scans for gastric cancer identify multiple risk loci. 53. Abstract from ICCFGG 2024, Helsinki, Finland.
Mandigers, P. (2024). Epilepsie bij de (ras)hond - een uitdaging, zowel genetisch als therapeutisch. In Epilepsie bij de (ras)hond - een uitdaging, zowel genetisch als therapeutisch (75 ed., pp. 23-28). Nederlandse Vereniging Klinische Neurofysiologie (NVKNF).
https://dspace.library.uu.nl/bitstream/handle/1874/452638/Epilepsie_bij_de_ras_hond_NVKNF_2024.pdf?sequence=1
Santifort, K. M., Carrera, I., & Mandigers, P. J. J. (2024). Longitudinal assessment of syringomyelia in Pomeranians. Frontiers in Veterinary Science, 11, 1-9. Article 1364464. https://doi.org/10.3389/fvets.2024.1364464
Boissevain, I. E., Jongbloed, A. W., & Mandigers, P. J. J. (2024). Orde in de praktijk, is dat wenselijk? Een vergelijking tussen het tuchtrecht voor advocaten en voor dierenartsen. Tijdschrift Tuchtrecht, 8, 7-13. Article 1.
https://dspace.library.uu.nl/bitstream/handle/1874/436960/Boissevain_e.a._Orde_in_de_praktijk.pdf?sequence=1
Santifort, K. M., Plonek, M., Kraijer‐Huver, I., Garosi, L., Rothacker, T., & Mandigers, P. (2024). Diagnosis of lymphoma based on magnetic resonance imaging, analysis of cerebrospinal fluid, intraocular fluid and fine‐needle aspirate of a uveal mass lesion in a dog. Veterinary Record Case Reports, 12(2), Article e814. https://doi.org/10.1002/vrc2.814
Limpens, C., Smits, V., Fieten, H., & Mandigers, P. (2024). The effect of MRI-based screening and selection on the prevalence of syringomyelia in the Dutch and Danish Cavalier King Charles Spaniels. Frontiers in Veterinary Science, 11, 1-9. Article 1326621. https://doi.org/10.3389/fvets.2024.1326621
https://dspace.library.uu.nl/bitstream/handle/1874/435941/fvets-11-1326621.pdf?sequence=1
Kinsey, N., Belanger, J. M., Mandigers, P. J. J., Leegwater, P. A., Heinonen, T., Hytönen, M. K., Lohi, H., Ostrander, E. A., & Oberbauer, A. M. (2024). Idiopathic Epilepsy Risk Allele Trends in Belgian Tervuren: A Longitudinal Genetic Analysis. Genes, 15(1), Article 114. https://doi.org/10.3390/genes15010114
https://dspace.library.uu.nl/bitstream/handle/1874/435745/genes-15-00114-v2.pdf?sequence=1

Vakpublicaties

Mandigers, P. (2024). Chiari-like malformatie en syringomyelie: Is de Cavalier King Charles Spaniel te redden? Tijdschrift voor Diergeneeskunde, 149(5), 14-15. https://www.knmvd.nl/chiari-like-malformatie-en-syringomyelie-is-de-cavalier-king-charles-spaniel-te-redden/

Populariserende publicaties

Mandigers, P. (2024). Cavalier mogelijk binnen enkele generaties SM-vrij. Onze Hond, 49(5), 6-9.
https://dspace.library.uu.nl/bitstream/handle/1874/452711/Onze-Hond_juni_2024_CKCS.pdf?sequence=1

2023

Wetenschappelijke publicaties

Santifort, K. M., Carrera, I., Bossens, K., & Mandigers, P. J. J. (2023). Phenotypic characterization of Pomeranians with or without Chiari-like malformation and syringomyelia. Frontiers in Veterinary Science, 10, Article 1320942. https://doi.org/10.3389/fvets.2023.1320942
Bontekoning, I., Maes, S. M. J., & Mandigers, P. J. J. (2023). A dog with protothecosis in the Netherlands. Veterinary Record Case Reports, Article e757. https://doi.org/10.1002/vrc2.757
Mandigers, P. J. J., & Santifort, K. M. (2023). Remarkable anecdotes illustrating the nature and effect of seizure-precipitating factors in Border Collies with idiopathic epilepsy. Frontiers in Veterinary Science, 10, Article 1254279. https://doi.org/10.3389/fvets.2023.1254279
Santifort, K. M., Plonek, M., & Mandigers, P. J. J. (2023). Case report: Neuropathic pain versus undesirable behavior in a Dachshund after hemilaminectomy surgery for an intervertebral disc extrusion. Frontiers in Veterinary Science, 10, Article 1223800. https://doi.org/10.3389/fvets.2023.1223800
Mandigers, P. J. J., Stehling, O., Vos-Loohuis, M., Van Steenbeek, F. G., Lill, R., & Leegwater, P. A. (2023). A novel IBA57 variant is associated with mitochondrial iron-sulfur protein deficiency and necrotizing myelopathy in dogs. Frontiers in Genetics, 14, Article 1190222. https://doi.org/10.3389/fgene.2023.1190222
Plonek, M., Santifort, K., Garosi, L., & Mandigers, P. (2023). Acute-onset seizures in a geriatric dog. Journal of the American Veterinary Medical Association, 261(11), 1735-1738. https://doi.org/10.2460/javma.23.04.0199
https://dspace.library.uu.nl/bitstream/handle/1874/433299/javma-javma.23.04.0199.pdf?sequence=1
Boissevain, I. E., Jongbloed, A. W., Meijboom, F. L. B., Hesselink, J. W., & Mandigers, P. J. J. (2023). Experiences and recommendations of veterinarians for the Dutch disciplinary system-a survey-based study. Veterinary Record Open, 10(1), Article e67. https://doi.org/10.1002/vro2.67
Santifort, K. M., Plonek, M., & Mandigers, P. J. J. (2023). Clinical Diagnosis of Rhabdomyolysis without Myoglobinuria or Electromyographic Abnormalities in a Dog. Animals, 13(11), 1-7. Article 1747. https://doi.org/10.3390/ani13111747
Opmeer, Y., Grinwis, G. C. M., Shelton, G. D., Rosati, M., Alf, V., Fieten, H., Leegwater, P. A. J., Matiasek, K., & Mandigers, P. J. J. (2023). An Inflammatory Myopathy in the Dutch Kooiker Dog. Animals, 13(9), Article 1508. https://doi.org/10.3390/ani13091508
Kijan, C., Hugen, S., Thomas, R. E., Oberbauer, A. M., Leegwater, P. A. J., Fieten, H., German, A. J., & Mandigers, P. J. J. (2023). The Histopathological Characteristic of Gastric Carcinoma in the Belgian Tervueren and Groenendael Dog: A Comparison of Two Classification Methods. Animals, 13(9), Article 1532. https://doi.org/10.3390/ani13091532
Plonek, M., Diaz-Espineira, M. M., Stassen, Q. E. M., Santifort, K. M., Leegwater, P. A. J., & Mandigers, P. J. J. (2023). Corrigendum: Phenotypic characterization of idiopathic epilepsy and epilepsy of unknown cause in Irish Setters (Front. Vet. Sci., (2022), 9, (1066094), 10.3389/fvets.2022.1066094). Frontiers in Veterinary Science, 10, 1-3. Article 1145556. https://doi.org/10.3389/fvets.2023.1145556
Beckers, E., Bhatti, S. F. M., Van Poucke, M., Polis, I., Farnir, F., Van Nieuwerburgh, F., Mandigers, P., Van Ham, L., Peelman, L., & Broeckx, B. J. G. (2023). Identification of a Novel Idiopathic Epilepsy Risk Locus and a Variant in the CCDC85A Gene in the Dutch Partridge Dog. Animals, 13(5), Article 810. https://doi.org/10.3390/ani13050810
Hamers, M., Plonek, M., Bhatti, S. F. M., Bergknut, N., Diaz Espineira, M., Santifort, K. M., & Mandigers, P. (2023). Quality of life in dogs with idiopathic epilepsy and their owners with an emphasis on breed: a pilot study. Frontiers in Veterinary Science, 9, Article 1107315. https://doi.org/10.3389/fvets.2022.1107315

Populariserende publicaties

Mandigers, P., & Ueckert, K. (2023). Hoe samenwerking een erfelijke ziekte liet verdwijnen. Onze Hond, 48(8), 48-49.
https://dspace.library.uu.nl/bitstream/handle/1874/432238/Samenwerking_loont_ENM_opgelost.pdf?sequence=1

2022

Wetenschappelijke publicaties

Santifort, K. M., Mandigers, P., Bergknut, N., Van Soens, I., & Carrera, I. (2022). Dysphonia in a dog with cervical spinal cord injury and suspected progressive myelomalacia caused by a C4-C5 hydrated nucleus pulposus extrusion. Vet Record Case Reports, 10(1), 1-6. Article e267. https://doi.org/10.1002/vrc2.267
Plonek, M., Diaz-Espineira, M. M., Stassen, Q. E. M., Santifort, K. M., Leegwater, P. A. J., & Mandigers, P. J. J. (2022). Phenotypic characterization of idiopathic epilepsy and epilepsy of unknown cause in Irish Setters. Frontiers in Veterinary Science, 9, Article 1066094. https://doi.org/10.3389/fvets.2022.1066094
Boissevain, I. E., van Rooij, M., Jongbloed, A. W., Meijboom, F. L. B., Hesselink, J. W., & Mandigers, P. J. J. (2022). 15 years of facts and figures on veterinary disciplinary measures in the Netherlands. Frontiers in Veterinary Science, 9, Article 987797. https://doi.org/10.3389/fvets.2022.987797
Jenkins, C., Luisa, D. R., Heinonen, T., Johnson, J., Kennedy, L., Short, A., Bhatti, S. F., Foster, D., Leegwater, P., Mandigers, P., Jokinen, T., Packer, R. M. A., Santifort, K. M., Volk, H. A., Mellersh, C. S., Hytönen, M., Lohi, H., & Ricketts, S. L. (2022). Idiopathic epilepsy in the Border Collie: using genome-wide association study and whole genome sequencing approaches to identify genetic risk factors. 59-59. Abstract from 11th International Conference on Canine and Feline Genetics and Genomics, Huntsville, Alabama, United States. https://online.flippingbook.com/view/187823506/59/
Belanger, J. M., Heinonen, T., Famula, T. R., Mandigers, P. J. J., Leegwater, P. A., Hytönen, M. K., Lohi, H., & Oberbauer, A. M. (2022). Validation of a Chromosome 14 Risk Haplotype for Idiopathic Epilepsy in the Belgian Shepherd Dog Found to Be Associated with an Insertion in the RAPGEF5 Gene. Genes, 13(7), 1-7. Article 1124. https://doi.org/10.3390/genes13071124
Santifort, K. M., & Mandigers, P. J. J. (2022). Dystonia in veterinary neurology. Journal of Veterinary Internal Medicine, 36(6), 1872-1881. https://doi.org/10.1111/jvim.16532
Polidoro, D., Temmerman, R., Devreese, M., Charalambous, M., Ham, L. V., Cornelis, I., Broeckx, B. J. G., Mandigers, P. J. J., Fischer, A., Storch, J., & Bhatti, S. F. M. (2022). Pharmacokinetics of Cannabidiol Following Intranasal, Intrarectal, and Oral Administration in Healthy Dogs. Frontiers in Veterinary Science, 9, 1-8. Article 899940. https://doi.org/10.3389/fvets.2022.899940
Lichtenauer, E. A., Evers, B., van den Broek, J., & Mandigers, P. J. J. (2022). Bromide Dose in Dogs With Epilepsy Living Close to Coastal Areas and Living More Inland: A Retrospective Observational Study. Frontiers in Veterinary Science, 9, 1-6. Article 906288. https://doi.org/10.3389/fvets.2022.906288
Santifort, K. M., Bertijn, E., Bhatti, S. F. M., Leegwater, P., Fischer, A., & Mandigers, P. J. J. (2022). Phenotypic Characterization of Idiopathic Epilepsy in Border Collies. Frontiers in Veterinary Science, 9, 1-7. Article 880318. https://doi.org/10.3389/fvets.2022.880318
Santifort, K., Beukers, M., Gil, V. A., Pijnenburg, J., Van Soens, I., Mandigers, P., & Bergknut, N. (2022). Fast three-dimensional contrast-enhanced magnetic resonance angiography of the canine lumbar spinal cord vascular supply: A feasibility study. Veterinary Radiology and Ultrasound, 63(6), 749-752. https://doi.org/10.1111/vru.13103
Santifort, K., Van Soens, I., Beukers, M., Grinwis, G., van der Lugt, J., & Mandigers, P. (2022). Papillary meningioma with multifocal leptomeningeal spread in a dog. Veterinary Record Case Reports, 10(2), 1-6. Article e325. https://doi.org/10.1002/vrc2.325

2021

Wetenschappelijke publicaties

de Boer, T. S., Diaz Espineira, M. M., & Mandigers, P. J. J. (2021). Is Encephalitozoon cuniculi of Significance in Young Dogs With Neurological Signs? Frontiers in Veterinary Science, 8, 1-6. Article 678968. https://doi.org/10.3389/fvets.2021.678968
Santifort, K. M., Ives, E. J., Fenn, J., Raimondi, F., Lourinho, F., Mandigers, P. J. J., & Bergknut, N. (2021). Suspected acquired narcolepsy in 8 dogs. Journal of Veterinary Internal Medicine, 35(3), 1448-1454. https://doi.org/10.1111/jvim.16116
Cerda-Gonzalez, S., Packer, R. A., Garosi, L., Lowrie, M., Mandigers, P. J. J., O'Brien, D. P., & Volk, H. A. (2021). International veterinary canine dyskinesia task force ECVN consensus statement: Terminology and classification. Journal of Veterinary Internal Medicine, 35(3), 1218-1230. https://doi.org/10.1111/jvim.16108
Mandigers, P. J. J., Van Steenbeek, F. G., Bergmann, W., Vos-Loohuis, M., & Leegwater, P. A. (2021). A knockout mutation associated with juvenile paroxysmal dyskinesia in Markiesje dogs indicates SOD1 pleiotropy. Human Genetics, 140(11), 1547-1552. https://doi.org/10.1007/s00439-021-02271-6
Santifort, K. M., & Mandigers, P. J. J. (2021). What is your neurologic diagnosis? Journal of the American Veterinary Medical Association, 258(3), 261-263. https://doi.org/10.2460/javma.258.3.261

2020

Wetenschappelijke publicaties

Letko, A., Minor, K. M., Friedenberg, S. G., Shelton, G. D., Salvador, J. P., Mandigers, P. J. J., Leegwater, P. A. J., Winkler, P. A., Petersen-Jones, S. M., Stanley, B. J., Ekenstedt, K. J., Johnson, G. S., Hansen, L., Jagannathan, V., Mickelson, J. R., & Drögemüller, C. (2020). A CNTNAP1 Missense Variant Is Associated with Canine Laryngeal Paralysis and Polyneuropathy. Genes, 11(12), Article 1426. https://doi.org/10.3390/genes11121426
Santifort, K. M., Hamers, M., & Mandigers, P. (2020). Epilepsy in veterinary patients: perspectives of Dutch veterinarians in first-line practice. Veterinary Record, 187(6), e44. https://doi.org/10.1136/vr.105806
Nessler, J., Hug, P., Mandigers, P. J. J., Leegwater, P. A. J., Jagannathan, V., Das, A. M., Rosati, M., Matiasek, K., Sewell, A. C., Kornberg, M., Hoffmann, M., Wolf, P., Fischer, A., Tipold, A., & Leeb, T. (2020). Mitochondrial PCK2 Missense Variant in Shetland Sheepdogs with Paroxysmal Exercise-Induced Dyskinesia (PED). Genes, 11(7). https://doi.org/10.3390/genes11070774
Brocal, J., Lowrie, M., Wamsley, G., Cauduro, A., Mandigers, P., Gutierrez-Quintana, R., & Stalin, C. (2020). Epileptic seizures triggered by eating in dogs. Journal of Veterinary Internal Medicine, 34(3), 1231-1238. https://doi.org/10.1111/jvim.15773

Populariserende publicaties

Mandigers, P. J. J. (2020). Chiari malformatie en syringomyelie: veel voorkomende aandoeningen bij de toybreeds. Onze Hond, 2020(6), 56-63.
https://dspace.library.uu.nl/bitstream/handle/1874/409202/OH06_gezondheid_kleineHondjes_P_v1.pdf?sequence=1
Mandigers, P. J. J. (2020). Epilepsie, adviezen voor de fokkerij. Onze Hond, 45(3), 55-59. Article 3.
https://dspace.library.uu.nl/bitstream/handle/1874/395232/OH03_Gezondheid_EpilepsieAdviezen_P_.pdf?sequence=1

2019

Wetenschappelijke publicaties

Wu, X., Mandigers, P. J. J., Watson, A. L., van den Ingh, T. S. G. A. M., Leegwater, P. A. J., & Fieten, H. (2019). Association of the canine ATP7A and ATP7B with hepatic copper accumulation in Dobermann dogs. Journal of Veterinary Internal Medicine, 33(4), 1646-1652. https://doi.org/10.1111/jvim.15536

Populariserende publicaties

Mandigers, P. J. J. (2019). Is het epilepsie of een bewegingsstoornis? Onze Hond, 44(10), 94-101.
https://dspace.library.uu.nl/bitstream/handle/1874/394511/OH10_Gezondheid_Epilepsie_P_.pdf?sequence=3

2018

Wetenschappelijke publicaties

Santifort, K. M., Kooistra, H. S., & Mandigers, P. J. J. (2018). Neurological signs due to hypoadrenocorticism in two dogs. Veterinary Record Case Reports, 6, Article 669. https://doi.org/10.1136/vetreccr-2018-000669
https://dspace.library.uu.nl/bitstream/handle/1874/376559/e000669.full.pdf?sequence=1
Santifort, K. M., Jurgens, B., Grinwis, G. C., Gielen, I., Meij, B. P., & Mandigers, P. J. (2018). Invasive nasal histiocytic sarcoma as a cause of epilepsy. JFMS open reports, 4(2). https://doi.org/10.1177/2055116918811179
Santifort, K. M., Luin, M. V., & Mandigers, P. J. J. (2018). Pyridostigmine bromide intoxication in two domestic cats. Veterinary Record Case Reports, 6(2). https://doi.org/10.1136/vetreccr-2018-000596
Minor, K. M., Letko, A., Becker, D., Drögemüller, M., Mandigers, P. J. J., Bellekom, S. R., Leegwater, P. A. J., Stassen, Q. E. M., Putschbach, K., Fischer, A., Flegel, T., Matiasek, K., Ekenstedt, K. J., Furrow, E., Patterson, E. E., Platt, S. R., Kelly, P. A., Cassidy, J. P., Shelton, G. D., ... Drögemüller, C. (2018). Canine NAPEPLD-associated models of human myelin disorders. Scientific Reports, 8(1), Article 5818. https://doi.org/10.1038/s41598-018-23938-7
Ancot, F., Lemay, P., Knowler, S. P., Kennedy, K., Griffiths, S., Cherubini, G. B., Sykes, J., Mandigers, P. J. J., Rouleau, G. A., Rusbridge, C., & Kibar, Z. (2018). A genome-wide association study identifies candidate loci associated to syringomyelia secondary to Chiari-like malformation in Cavalier King Charles Spaniels. BMC Genetics, 19(1), Article 16. https://doi.org/10.1186/s12863-018-0605-z

2017

Wetenschappelijke publicaties

Wijnrocx, K., Van Bruggen, L. W. L., Eggelmeijer, W., Noorman, E., Jacques, A., Buys, N., Janssens, S., & Mandigers, P. J. J. (2017). Twelve years of chiari-like malformation and syringomyelia scanning in Cavalier King Charles Spaniels in the Netherlands: Towards a more precise phenotype. PLoS One, 12(9), Article e0184893. https://doi.org/10.1371/journal.pone.0184893
Mandigers, P. J. J. (2017). Het voorkomen van epilepsie bij de Nederlandse hondenrassen. Tijdschrift voor Diergeneeskunde, 142(2), 28-31.
https://dspace.library.uu.nl/bitstream/handle/1874/433966/Het_voorkomen_van_epilepsie_bij_de_Nederlandse_hondenrassen_02_2017.pdf?sequence=1
Hugen, S., Thomas, R. E., German, A. J., Burgener, I. A., & Mandigers, P. J. J. (2017). Gastric carcinoma in canines and humans, a review. Veterinary and Comparative Oncology, 15(3), 692-705. https://doi.org/10.1111/vco.12249

Overige resultaten

Hamers, M. F. N., Diaz Espineira, M. M., & Mandigers, P. J. J. (2017). Canine epilepsy: a survey on the owners' perspective of quality of life.. Abstract from Voorjaarsdagen 2017.
https://dspace.library.uu.nl/bitstream/handle/1874/396324/Canine_epilepsy_a_survey_on_the_owners_perspective_of_quality_of_life_Maud_Hamers.pdf?sequence=1
Boer, T. S. D., Boswijk-Appelhof, L. C., Diaz Espineira, M. M., & Mandigers, P. J. J. (2017). The clinical significance of Encephalitozoon cuniculi in young dogs with neurological signs.. Abstract from Voorjaarsdagen 2017.
https://dspace.library.uu.nl/bitstream/handle/1874/395245/The_clinical_significance_of_encephalitozoon_cuniculi_in_young_dogs_with_neurological_signs_Tamar_de_Boer.pdf?sequence=1
Wijnrocx, K., Bruggen, L. W. L. V., Eggelmeijer, W., Noorman, E., Jacques, A., Buys, N., Janssens, S., & Mandigers, P. J. J. (2017). Twelve years of Chiari-like malformation and syringomyelia scanning in Cavalier King Charles Spaniels in the Netherlands: can we get away from it?. Abstract from Voorjaarsdagen 2017.
https://dspace.library.uu.nl/bitstream/handle/1874/396323/Twelve_years_of_chiari_like_malformation_and_syringomyelia_scanning_in_Cavalier_King_Charles_Spaniels_in_the_Netherlands_can_we_get_away_from_it_Katrien_Wijnrocx.pdf?sequence=1
Verstrepen, B. E., Fagrouch, Z., Drenthen, J., Heteren, M. V., Oostermeijer, H., Haaksma, T., Huizinga, R., Jacobs, B., Mandigers, P. J. J., Bogers, W. M., Kondova, I., & Verschoor, E. J. (2017). Experimental infection of rhesus macaques with Zika virus. Abstract from Dutch Annual Virology Symposium, Amsterdam, Netherlands.
Minor, K., Letko, A., Becker, D., Mandigers, P. J. J., Bellekom, S. R., Leegwater, P. A. J., Putschbach, K., Fischer, A., Flegel, T., Matiasek, K., Furrow, E., Patterson, N., Platt, S. R., Kelly, P. A., Shelton, G. D., Martineau, H., Muir, C., Priestnall, S. L., Oevermann, A., ... Drogemuller, C. (2017). Mutations of NAPEPLD independently associated with leukoencephalomyelopathy in Leonberger and Rottweiler dogs.. Abstract from (th dog and cat genetic conference, Minnesota, United States.

2016

Wetenschappelijke publicaties

Bhatti, S., De Risio, L., Muñana, K., Penderis, J., Stein, V. M., Tipold, A., Berendt, M., Farquhar, R., Fischer, A., Long, S., Löscher, W., Mandigers, P. J. J., Matiasek, K., Pakozdy, A., Patterson, N., Platt, S., Podell, M., Potschka, H., Rusbridge, C., & Volk, H. A. (2016). Epilepsie aktuell - Zusammenfassung der IVETF-Empfehlungen zum "Therapeutischen Management der kaninen Epilepsie in Europa". Kleintierpraxis, 61(10), 529-544. https://doi.org/10.2377/0023-2076-61-529
https://dspace.library.uu.nl/bitstream/handle/1874/346792/Kleintierpraxis_Treatment_Okt_2016.pdf?sequence=1
De Risio, L., Bhatti, S., Muñana, K., Penderis, J., Stein, V. M., Tipold, A., Berendt, M., Farqhuar, R., Fischer, A., Long, S., Mandigers, P. J. J., Matiasek, K., Packer, R. M. A., Pakozdy, A., Patterson, N., Platt, S., Potschka, H., Pumarola, M. B., Rusbridge, C., & Volk, H. A. (2016). Epilepsie aktuell - Zusammenfassung des Konsens papiers des IVETF "Vorschlag fur die diagnostische Herangehensweise bei Hunden mit Epilepsie". Kleintierpraxis, 61(9), 477-487. https://doi.org/10.2377/0023-2076-61-477
Berendt, M., Hülsmeyer, V.-I., Bhatti, S., De Risio, L., Farquhar, R., Fischer, A., Mandigers, P. J. J., & Long, S. (2016). Epilepsie aktuell - Zusammenfassung der Konsens papiers der IVETF zur Definition der Epilepsie, ihrer Klassifikation und der Terminologie sowie zur Genetik der Erkrankung bei Rassehunden. Kleintierpraxis, 61(8), 425-435. https://doi.org/10.2377/0023-2076-61-425

Vakpublicaties

Mandigers, P. J. J. (2016). Feline Hyperesthesie Syndroom. Tijdschrift voor Diergeneeskunde, 2016(3), 2-3.
https://dspace.library.uu.nl/bitstream/handle/1874/345972/Feline_Hyperaesthesie_TVD0716.pdf?sequence=1
L.M.J., V., Grinwis, G. C. M., Bergknut, P. N., & Mandigers, P. J. J. (2016). Dysautonomie bij de hond. Tijdschrift voor Diergeneeskunde, 2016(2), 24-27.
https://dspace.library.uu.nl/bitstream/handle/1874/345944/Dysautonomie_hond_TvD_2016.pdf?sequence=1

2015

Wetenschappelijke publicaties

Potschka, H., Fischer, A., Löscher, W., Patterson, N., Bhatti, S., Berendt, M., De Risio, L., Farquhar, R., Long, S., Mandigers, P., Matiasek, K., Muñana, K., Pakozdy, A., Penderis, J., Platt, S., Podell, M., Rusbridge, C., Stein, V., Tipold, A., & Volk, H. A. (2015). International veterinary epilepsy task force consensus proposal: outcome of therapeutic interventions in canine and feline epilepsy. BMC Veterinary Research, 11, Article 177. https://doi.org/10.1186/s12917-015-0465-y
Berendt, M., Farquhar, R. G., Mandigers, P. J. J., Pakozdy, A., Bhatti, S. F. M., De Risio, L., Fischer, A., Long, S., Matiasek, K., Muñana, K., Patterson, E. E., Penderis, J., Platt, S., Podell, M., Potschka, H., Pumarola, M. B., Rusbridge, C., Stein, V. M., Tipold, A., & Volk, H. A. (2015). International veterinary epilepsy task force consensus report on epilepsy definition, classification and terminology in companion animals. BMC Veterinary Research, 11, Article 182. https://doi.org/10.1186/s12917-015-0461-2
De Risio, L., Bhatti, S., Muñana, K., Penderis, J., Stein, V., Tipold, A., Berendt, M., Farqhuar, R., Fischer, A., Long, S., Mandigers, P. J. J., Matiasek, K., Packer, R. M. A., Pakozdy, A., Patterson, N., Platt, S., Podell, M., Potschka, H., Batlle, M. P., ... Volk, H. A. (2015). International veterinary epilepsy task force consensus proposal: diagnostic approach to epilepsy in dogs. BMC Veterinary Research, 11, Article 148. https://doi.org/10.1186/s12917-015-0462-1
Hülsmeyer, V.-I., Fischer, A., Mandigers, P. J. J., DeRisio, L., Berendt, M., Rusbridge, C., Bhatti, S. F. M., Pakozdy, A., Patterson, E. E., Platt, S., Packer, R. M. A., & Volk, H. A. (2015). International Veterinary Epilepsy Task Force's current understanding of idiopathic epilepsy of genetic or suspected genetic origin in purebred dogs. BMC Veterinary Research, 11, 175. https://doi.org/10.1186/s12917-015-0463-0
Bhatti, S. F. M., De Risio, L., Muñana, K., Penderis, J., Stein, V. M., Tipold, A., Berendt, M., Farquhar, R. G., Fischer, A., Long, S., Löscher, W., Mandigers, P. J. J., Matiasek, K., Pakozdy, A., Patterson, E. E., Platt, S., Podell, M., Potschka, H., Rusbridge, C., & Volk, H. A. (2015). International Veterinary Epilepsy Task Force consensus proposal: medical treatment of canine epilepsy in Europe. BMC Veterinary Research, 11, Article 176. https://doi.org/10.1186/s12917-015-0464-z
Overduin, L. M., & Mandigers, P. J. J. (2015). Epilepsie bij de hond, deel 2: de behandeling. Tijdschrift voor Diergeneeskunde, 140(9), 24-30.
https://dspace.library.uu.nl/bitstream/handle/1874/327187/Epilepsie_bij_de_hond_TvD_2015_deel_2.pdf?sequence=1
Mandigers, P. J. J., & Overduin, L. M. (2015). Epilepsie bij de hond, deel 1: indeling en classificatie. Tijdschrift voor Diergeneeskunde, 140(7), 30-35.
https://dspace.library.uu.nl/bitstream/handle/1874/327186/Epilepsie_bij_de_hond_TvD_2015_deel_1.pdf?sequence=1
Packer, R. M., Berendt, M., Bhatti, S., Charalambous, M., Cizinauskas, S., De Risio, L., Farquhar, R., Hampel, R., Hill, M., Mandigers, P. J., Pakozdy, A., Preston, S. M., Rusbridge, C., Stein, V. M., Taylor-Brown, F., Tipold, A., & Volk, H. A. (2015). Inter-observer agreement of canine and feline paroxysmal event semiology and classification by veterinary neurology specialists and non-specialists. BMC Veterinary Research, 11(1), 356. https://doi.org/10.1186/s12917-015-0356-2

2014

Wetenschappelijke publicaties

Mandigers, P. J. J., Duijvestijn, M. B. H. M., Ankringa, N., Maes, S., van Essen, E., Schoormans, A. H. W., German, A. J., & Houwers, D. J. (2014). The clinical significance of Cyniclomyces guttulatus in dogs with chronic diarrhoea, a survey and a prospective treatment study. Veterinary Microbiology, 172, 241-247. https://doi.org/10.1016/j.vetmic.2014.05.018
Mandigers, P. J. J. (2014). Het gebruik van bromide als anti-epilepticum bij de hond. Tijdschrift voor Diergeneeskunde, 138(2), 42-44.

2012

Wetenschappelijke publicaties

van den Schuurmans, A. B. J., & Mandigers, P. J. J. (2012). A correlation between potassium bromide dose and serumlevel. ECVN.

2010

Wetenschappelijke publicaties

Mandigers, P. J. J., Biourge, V., & German, A. J. (2010). Efficacy of a commercial hydrolysate diet in eight cats suffering from inflammatory bowel disease or adverse reaction to food. Tijdschrift voor Diergeneeskunde, 135(18), 668-72.
van Dijl, I., & Mandigers, P. (2010). Enquête 'Verwijzen in de praktijk'. Tijdschrift voor Diergeneeskunde, 135(2), 62-5.
Mandigers, P., & German, A. J. (2010). Dietary hypersensitivity in cats and dogs. Tijdschrift voor Diergeneeskunde, 135(19), 706-10.
Mandigers, P. J. J., Biourge, V., van den Ingh, T. S. G. A. M., Ankringa, N., & German, A. J. (2010). A randomized, open-label, positively-controlled field trial of a hydrolyzed protein diet in dogs with chronic small bowel enteropathy. Journal of Veterinary Internal Medicine, 24(6), 1350-1357.

Vakpublicaties

Mandigers, P. (2010). De gruwel en het dogmatisme van een verplicht pensioenfonds. Tijdschrift voor Diergeneeskunde, 135(17), 650.

2009

Wetenschappelijke publicaties

Mandigers, P., & Rusbridge, C. (2009). Op Chiari lijkende malformatie- Syringomyelie bij de Cavalier King Charles Spaniël. Tijdschrift voor Diergeneeskunde, 134(18), 746-50.

Vakpublicaties

Lubbes, D., Mandigers, P. J. J., Heuven, H. C. M., & Teske, E. (2009). [Incidence of gastric carcinoma in Dutch Tervueren shepherd dogs born between 1991 and 2002]. Tijdschrift voor Diergeneeskunde, 134, 606-610.
https://dspace.library.uu.nl/bitstream/handle/1874/322916/2009_Lubbes_Maagcarc_Tervurense_Herder_TvD.pdf?sequence=1

2008

Wetenschappelijke publicaties

Michiels, L., Reusch, C. E., Boari, A., Petrie, G., Mandigers, P., Thollot, I. G., Rosenberg, D., Mooney, C., Bonfanti, U., Font, A., Sparkes, A., Bewig, K., Clercx, C., Jensen, A. L., & Horspool, L. J. I. (2008). Treatment of 46 cats with porcine lente insulin--a prospective, multicentre study. Journal of Feline Medicine and Surgery, 10(5), 439-51. https://doi.org/10.1016/j.jfms.2007.10.013

2007

Wetenschappelijke publicaties

Mandigers, P. J. J., Bode, P., van Wees, A. M. T. C., van den Brom, W. E., van den Ingh, T. S. G. A. M., & Rothuizen, J. (2007). Hepatic (64)Cu excretion in Dobermanns with subclinical hepatitis. Research in Veterinary Science, 83(2), 204-9. https://doi.org/10.1016/j.rvsc.2006.12.006

2006

Wetenschappelijke publicaties

Mandigers, P. J. J., Senders, T., & Rothuizen, J. (2006). Morbidity and mortality in 928 Dobermanns born in the Netherlands between 1993 and 1999. Veterinary Record, 158, 226-229.
https://dspace.library.uu.nl/bitstream/handle/1874/20220/Mandigers%2C%2520Senders%2C%2520Rothuizen%2520-%2520Morbidity%2520and%2520mortality%2520in%2520928%2520Dobermanns%2520born%2520in%2520the%2520Netherlands%2520between%25201993%2520and%25201999.pdf?sequence=1

2005

Wetenschappelijke publicaties

Mandigers, P. J. J., Horspool, L. J. L., van den Ingh, T. S. G. A. M., Teske, E., Bode, P., & Rothuizen, J. (2005). Double-blind, placebo-controlled study of the efficacy of nandrolone laurate in the treatment of dobermanns with subclinical hepatitis. Veterinary Record, 157(11), 313-317.
https://dspace.library.uu.nl/bitstream/handle/1874/377379/2005_Mandigers_Vet_Rec.pdf?sequence=1
Mandigers, P. J. J., van den Ingh, T. S. G. A. M., Bode, P., & Rothuizen, J. (2005). Improvement in liver pathology after 4 months of D-penicillamine in 5 doberman pinschers with subclinical hepatitis. Journal of Veterinary Internal Medicine, 19(1), 40-43.
Mandigers, P. (2005). Methoden van niet-invasieve bloeddrukmeting bij de hond en kat. Tijdschrift voor Diergeneeskunde, 130(7), 198-201.
Mandigers, P. J. J. (2005). Insights in the pathogenesis of Dobermann hepatitis. [Doctoral thesis 1 (Research UU / Graduation UU), Utrecht University]. https://dspace.library.uu.nl:8443/handle/1874/1763
Mandigers, P. J. J. (2005). The making, evaluation and use of ECG's in practice. In M. C. Labberte (Ed.), Symposium State of the Haert, Labberte, M.C. vol 2 (pp. 11-13)
Mandigers, P. J. J. (2005). Erfelijkheid van epilepsie bij de hond. In E. Gruys (Ed.), Gruys E. vol 3 (pp. 1-9)
Mandigers, P. J. J. (2005). Gastrointestinalne problemy. In Brauner Tibor Dr. (pp. 4-16)
Spee, B., Mandigers, P. J. J., Arends, B., Bode, P., van den Ingh, T. S. G. A. M., Hoffmann, G., Rothuizen, J., & Penning, L. C. (2005). Differential expression of copper-associated and oxidative stress related proteins in a new variant of copper toxicosis in Doberman pinschers. Comparative Hepatology, 4(3), 1-13.

Populariserende publicaties

van, D. E. W., den, H. A., Gostelie, E., Verburgh, M., Bouwhuis, G., Hooijer, GA., van, D. F., Urlings, B., van, M. J., Hof, M., & Mandigers, P. (2005). Brief aan de leden van de KNMvD Tussenstand nieuw kwaliteitsbeleid. Tijdschrift voor Diergeneeskunde, 130(13), 428 - 429.

2004

Wetenschappelijke publicaties

Mandigers, P. J. J., van den Ingh, T. S. G. A. M., Bode, P., Teske, E., & Rothuizen, J. (2004). Association between liver copper concentration and subclinical hepatitis in Doberman Pinschers. Journal of Veterinary Internal Medicine, 18(5), 647-50.
Mandigers, P. J. J., van den Ingh, T. S. G. A. M., Bode, P., Teske, E., & Rothuizen, J. (2004). Association between liver copper concentration and subclinical hepatitis in Doberman Pinchers. Journal of Veterinary Internal Medicine, 18, 647-650. https://doi.org/10.1111/j.1939-1676.2004.tb02600.x
https://dspace.library.uu.nl/bitstream/handle/1874/322905/2004_Mandigers_JVIM.pdf?sequence=1
Mandigers, P. J. J., van den Ingh, T. S. G. A. M., Spee, B., Penning, L. C., Bode, P., & Rothuizen, J. (2004). Chronic hepatitis in Doberman pinschers. A review. Veterinary Quarterly, 26(3), 99-106.
Mandigers, P. J. J., van den Ingh, T. S. G. A. M., Spee, B., Penning, L. C., & Rothuizen, J. (2004). The pathogenesis of Doberman hepatitis. In 14th Symposium ECVIM-CA (pp. 120-123)

Vakpublicaties

Houwers, D. J., van Duijkeren, E., Bosje, J. T., Gerritsen, R. J., den Hertog, E. J., Mandigers, P. J. J., van Noort, R., & Overduin, L. M. (2004). Antimicrobiële middelen bij hond en kat met diarree. Tijdschrift voor Diergeneeskunde, 129(7), 221-222.

2002

Wetenschappelijke publicaties

Mandigers, P. (2002). [European congress about aging of the brain in dogs]. Tijdschrift voor Diergeneeskunde.
Mandigers, P. J. J., Nell, T., & Mandigers, P. J. J. (2002). Treatment of bitches with acquired urinary incontinence with oestriol. Veterinary Record, 149(25), 764-7.

2000

Wetenschappelijke publicaties

Mandigers, P. J. J., van den Ingh, T. S. G. A. M., Bode, P., Teske, E., Ubbink, G. J., & Rothuizen, J. (2000). Incidence of subclinical hepatitis in three year old Dobermanns and associated liver values. In Proceedings of the Xth ESVIM Annual Congress (pp. 58-59).

1998

Wetenschappelijke publicaties

van den Ingh, T. S. G. A. M., Mandigers, PJ., & van, N. JJ. (1998). A neuronal vacuolar disorder in young rottweiler dogs. The Veterinary record, 142(10), 245-247. https://doi.org/10.1136/vr.142.10.245

1997

Wetenschappelijke publicaties

Mandigers, P. (1997). Verloskundige waarnemingen van veearts W. Munter (1767-1838) uit Goudswaard (Z.-H.). Argos, (17), 281-9.

1996

Wetenschappelijke publicaties

Mandigers, P. J. J., & Stokhof, A. A. (1996). A computerized ECG analyzer. Veterinary Quarterly, 18(sup1), 56-57. https://doi.org/10.1080/01652176.1996.9694686

1994

Wetenschappelijke publicaties

Mandigers, P. J., Kooistra, H. S., van der Gaag, I., Selman, P. J., & Rutteman, G. R. (1994). Een teef die progressief slomer en heser werd. Tijdschrift voor Diergeneeskunde, 119(1), 6-9.
Mandigers, P. J., van Nes, J. J., & Voorhout, G. (1994). Intracranial tumors: a diagnostic challenge. Veterinary Quarterly, 16 Suppl 1, 62S.
Mandigers, P. J. (1994). De oprichting van de Veterinaire Studentenrijvereniging De Solleysel. Tijdschrift voor Diergeneeskunde, 119(8), 238-41.
Mandigers, P. J., Ubbink, G. J., Vanden Broek, J., & Bouw, J. (1994). Relationship between litter size and other reproductive traits in the Dutch Kooiker dog. Veterinary Quarterly, 16(4), 229-32. https://doi.org/10.1080/01652176.1994.9694454

1993

Wetenschappelijke publicaties

Mandigers, P. J., van der Hage, M. H., Westerhof, I., & Dorrestein, G. M. (1993). Een veldonderzoek naar de effectiviteit van ivermectine in propyleenglycol bij de behandeling van schurft bij cavia's. Tijdschrift voor Diergeneeskunde, 118(2), 42-6.
Mandigers, P. J., Van Nes, J. J., Knol, B. W., Ubbink, G. J., & Gruys, E. (1993). Hereditary necrotising myelopathy in Kooiker dogs. Research in Veterinary Science, 54(1), 118-23.
Mandigers, P. J., van Nes, J. J., Knol, B. W., Ubbink, G. J., & Gruys, E. (1993). Hereditary Kooiker dog ataxia. Tijdschrift voor Diergeneeskunde, 118 Suppl 1, 65S.

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