Publicaties
2025
Wetenschappelijke publicaties
Cox, K., Verschaeve, L., van den Brand, J. M. A., & Huysentruyt, F. (2025). Genetic consequences of beaver reintroduction in a multi-lineage contact zone. European Journal of Wildlife Research, 72(1), Article 7. [DOI]
Kok, A., Wilks, S. H., Tureli, S., James, S. L., Bestebroer, T. M., Burke, D. F., Funk, M., van der Vliet, S., Spronken, M. I., Rijnink, W. F., Pattinson, D. J., de Meulder, D., Rosu, M. E., Lexmond, P., van den Brand, J. M. A., Herfst, S., Smith, D. J., Fouchier, R. A. M., & Richard, M. (2025). A vaccine central in A(H5) influenza antigenic space confers broad immunity. Nature, 647(8091), 1005-1013. [DOI] [Portal]
Füll, Y., Schüssele, L. M., Hamza, H., Hoffmann, H., Bauer, M., Stenglein, S., Pötz, O., Steinhilber, A., Anselm, V., Delany, M. W., Van den Brand, J. M. A., Van Amerongen, G., De Waal, L., Pleschka, S., Ludwig, S., & Planz, O. (2025). Antiviral and immunomodulatory effect of zapnometinib in animal models and hospitalized COVID-19 patients. Frontiers in Immunology, 16, 1-21. Article 1631721. [DOI] [Portal]
Schipper, J. G., Aloise, C., Sutter, S. O., Zwaagstra, M., van Vliet, A. L. W., Abdelnabi, R., Ignacio, B., Bonger, K. M., Roelofs, D., van den Brand, J. M. A., Wubbolts, R. W., Bruurs, L. J. M., Thibaut, H. J., Neyts, J., Tanenbaum, M. E., & van Kuppeveld, F. J. M. (2025). The multifaceted role of the viral 2A protease in enterovirus replication and antagonism of host antiviral responses. PLoS Pathogens, 21(8 ), Article e1013443. [DOI] [Portal]
Münger, E., Atama, N. C., van Irsel, J., Blom, R., Krol, L., van Mastrigt, T., van den Berg, T. J., Braks, M., de Vries, A., van der Linden, A., Chestakova, I., Boter, M., Chandler, F. D., Kohl, R., Nieuwenhuijse, D. F., Uiterwijk, M., Fouchier, R. A. M., Sprong, H., Gröne, A., ... Koopmans, M. P. G. (2025). One Health approach uncovers emergence and dynamics of Usutu and West Nile viruses in the Netherlands. Nature Communications, 16(1), Article 7883. [DOI] [Portal]
Fischer, L., de Bruin, E., Jongepier, E., Koffeman, E., König, P., Pfaff, F., Peters, M., van den Brand, J. M. A., Bussi, M., Fischer, D., Caliendo, V., Weerts, E., IJzer, J., Müller, J., Kühling, A.-K., Kummerfeld, M., Müller, J., Petersen, H., Merbach, S., ... Rijks, J. M. (2025). Recombinant Myxoma Virus in European Brown Hares, 2023-2024. Emerging Infectious Diseases, 31(8), 1608-1612. [DOI] [Portal]
Duijvestijn, M. B. H. M., Schuurman, N. N. M. P., Vernooij, J. C. M., Broekhuizen, M. J., de Bruin, E., Carrière, B. S., van den Brand, J. M. A., Wagenaar, J. A., van Kuppeveld, F. J. M., Egberink, H. F., de Haan, C. A. M., & Verhagen, J. H. (2025). Hunting-training dogs and companion dogs in the Netherlands are frequently exposed to highly pathogenic avian influenza (HPAI H5) and human H1N1 virus, 2021–2023. One Health, 21, Article 101134. [DOI] [Portal]
Agliani, G., Visser, I., Marshall, E. M., Giglia, G., de Bruin, E., Verstappen, R., van Mastrigt, T., Chandler, F., Sikkema, R., van der Jeugd, H., Koopmans, M. P. G., Gröne, A., Rockx, B., & van den Brand, J. M. A. (2025). Experimental Usutu virus infection in Eurasian blackbirds (Turdus merula). NPJ Viruses, 3(1), Article 51. [DOI] [Portal]
Giglia, G., Münger, E., Mencattelli, G., Agliani, G., Berends, A. J., Valleriani, F., Filipponi, G., Gavaudan, S., Di Gennaro, A., Fast, C., Sikkema, R. S., Kik, M., Koopmans, M. P. G., Mandara, M. T., Gröne, A., Oude Munnink, B. B., van den Brand, J. M. A., Reusken, C. B. E. M., Monaco, F., & Savini, G. (2025). Usutu virus-disease susceptibility in threatened red-breasted geese (Branta ruficollis) in Italy and the Netherlands. Journal of Comparative Pathology, 219, 98-101. [DOI] [Portal]
Caliendo, V., Martin, B. B., Fouchier, R. A. M., Vuong, O., van den Brand, J. M. A., Leopold, M., & Kühn, S. (2025). Highly Pathogenic Avian Influenza in Northern Fulmars (Fulmarus glacialis) in the Netherlands. Journal of Wildlife Diseases, 61(3), 792-796. [DOI]
Giglia, G., Agliani, G., van Eijk, N. M. H. A., de Bruin, E., Fast, C., Sikkema, R. S., Oude Munnink, B. B., Mandara, M. T., Gröne, A., & van den Brand, J. M. A. (2025). Ocular and periocular Usutu virus-associated lesions in naturally infected Eurasian blackbirds (Turdus merula). Veterinary Pathology, 62(5), 773-780. [DOI] [Portal]
Begeman, L., Geschiere, M. J. M., de Boer, W. F., van den Brand, J. M. A., Eblé, P. L., van der Kerkhof, J. H. T. C., Keur, I., Lina, P. H. C., Reusken, C. B. E. M., de Rosa, M., Schillemans, M. J., Schreuder, I., Swaan, C. M., van Zoonen, K., & Kuiken, T. (2025). Human-bat contacts in the Netherlands, and potential risks for virus exchange. One Health Outlook, 7(1), Article 7. [DOI] [Portal]
Rissmann, M., Noack, D., Spliethof, T. M., Vaes, V. P., Stam, R., van Run, P., Clark, J. J., Verjans, G. M. G. M., Haagmans, B. L., Krammer, F., Koopmans, M. P. G., van den Brand, J. M. A., & Rockx, B. (2025). A pan-orthohantavirus human lung xenograft mouse model and its utility for preclinical studies. PLoS Pathogens, 21(1), Article e1012875. [DOI] [Portal]
2024
Wetenschappelijke publicaties
Böszörményi, K. P., Stammes, M. A., Fagrouch, Z., Acar, F., Niphuis, H., Kayere, G. K., Meijer, L., Snijder, E. J., van der Hoek, L., Berkhout, B., Bogers, W. M., van den Brand, J. M. A., Kondova, I., Verstrepen, B. E., & Verschoor, E. J. (2024). Prolonged fecal shedding of replication-competent virus, lasting immune activation, and intestinal inflammation in a rhesus macaque after experimental SARS-CoV-2 infection. Frontiers in cellular and infection microbiology, 14, Article 1505720. [DOI] [Portal]
Kok, A., Wilks, S. H., Tureli, S., James, S. L., Bestebroer, T. M., Burke, D. F., Funk, M., van der Vliet, S., Spronken, M. I., Rijnink, W. F., Pattinson, D., de Meulder, D., Rosu, M. E., Lexmond, P., van den Brand, J. M. A., Herfst, S., Smith, D. J., Fouchier, R. A. M., & Richard, M. (2024). A vaccine antigen central in influenza A(H5) virus antigenic space confers subtype-wide immunity. (bioRxiv). bioRxiv. [DOI] [Portal]
Duijvestijn, M. B. H. M., Schuurman, N. N. M. P., Vernooij, J. C. M., van Leeuwen, M. A. J. M., van den Brand, J. M. A., Wagenaar, J. A., van Kuppeveld, F. J. M., Egberink, H. F., de Haan, C. A. M., & Verhagen, J. H. (2024). Highly pathogenic avian influenza (HPAI) H5 virus exposure in domestic cats and rural stray cats, the Netherlands, October 2020 to June 2023. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 29(44), Article pii=2400326. [DOI] [Portal]
Eggink, H., Maas, M., van den Brand, J. M. A., Dekker, J., Franssen, F., Hoving, E. W., Kortbeek, L. M., Kranendonk, M. E. G., Meiners, L. C., Rittscher, A. E., Roelfsema, J., & Schölvinck, E. H. (2024). Taenia martis Neurocysticercosis-Like Lesion in Child, Associated with Local Source, the Netherlands. Emerging Infectious Diseases, 30(3), 555-559. [DOI] [Repository]
Giglia, G., Gianfilippo, A., Mandara, M. T., de Bruin, E., Gröne, A., & van den Brand, J. M. A. (2024). Usutu virus avian and human infection after more than 25 years of circulation. European Journal of Clinical Microbiology and Infectious Diseases, 43(4), 805-807. [DOI] [Repository]
Mollerup, I.-M., Bjørneset, J., Krock, B., Jensen, T. H., Galatius, A., Dietz, R., Teilmann, J., van den Brand, J. M. A., Osterhaus, A., Kokotovic, B., Lundholm, N., & Olsen, M. T. (2024). Did algal toxin and Klebsiella infections cause the unexplained 2007 mass mortality event in Danish and Swedish marine mammals? Science of the Total Environment, 914, Article 169817. [DOI]
Populariserende publicaties
Rijks, J., Caliendo, V., Beerens, N., Sikkema, R. S., van den Brand, JM., & Slaterus, R. (2024). Wild zoogdier besmet met het hoogpathogene H5N1-vogelgriepvirus. De levende natuur, 125(2), 53-56. https://stats.sovon.nl/pub/publicatie/21660 [Portal]
Montizaan, M., van den Brand, JM., & Slaterus, R. (2024). Het ‘merelvirus’ gaat nog steeds rond. De levende natuur, 125(2), 57-60. https://stats.sovon.nl/pub/publicatie/21661 [Portal]
2023
Wetenschappelijke publicaties
Chestakova, I. V., van der Linden, A., Bellido Martin, B., Caliendo, V., Vuong, O., Thewessen, S., Hartung, T., Bestebroer, T., Dekker, J., Jonge Poerink, B., Gröne, A., Koopmans, M., Fouchier, R., van den Brand, J. M. A., & Sikkema, R. S. (2023). High number of HPAI H5 virus infections and antibodies in wild carnivores in the Netherlands, 2020-2022. Emerging Microbes and Infections, 12(2), Article 2270068. [DOI] [Repository]
Laksono, B. M., Roelofs, D., Comvalius, A. D., Schmitz, K. S., Rijsbergen, L. C., Geers, D., Nambulli, S., van Run, P., Duprex, W. P., van den Brand, J. M. A., de Vries, R. D., & de Swart, R. L. (2023). Infection of ferrets with wild type-based recombinant canine distemper virus overwhelms the immune system and causes fatal systemic disease. mSphere, 8(4), Article e0008223. [DOI] [Repository]
Agliani, G., Giglia, G., Marshall, E. M., Gröne, A., Rockx, B. H. G., & van den Brand, J. M. A. (2023). Pathological features of West Nile and Usutu virus natural infections in wild and domestic animals and in humans: A comparative review. One Health, 16, Article 100525. [DOI] [Repository]
Agliani, G., Giglia, G., de Bruin, E., van Mastrigt, T., Blom, R., Sikkema, R. S., Kik, M., Koopmans, M. P. G., Gröne, A., & Van den Brand, J. M. A. (2023). The pathology of co-infection with Usutu virus and Plasmodium spp. in naturally infected Eurasian blackbirds (Turdus merula). One Health, 16, Article 100534. [DOI] [Repository]
Roelofs, D., Schmitz, K. S., van Amerongen, G., Rijsbergen, L. C., Laksono, B. M., Comvalius, A. D., Nambulli, S., Rennick, L. J., van Run, P., Duprex, W. P., van den Brand, J. M. A., de Swart, R. L., & de Vries, R. D. (2023). Inoculation of raccoons with a wild-type-based recombinant canine distemper virus results in viremia, lymphopenia, fever, and widespread histological lesions. mSphere, 8(4), 1-18. Article e0014423. [DOI] [Repository]
Gerhards, N. M., Gonzales, J. L., Vreman, S., Ravesloot, L., van den Brand, J. M. A., Doekes, H. P., Egberink, H. F., Stegeman, A., Oreshkova, N., van der Poel, W. H. M., & de Jong, M. C. M. (2023). Efficient Direct and Limited Environmental Transmission of SARS-CoV-2 Lineage B.1.22 in Domestic Cats. Microbiology spectrum, 11(3), Article e0255322. [DOI] [Repository]
Vreman, S., van der Heijden, E. M. D. L., Ravesloot, L., Ludwig, I. S., van den Brand, J. M. A., Harders, F., Kampfraath, A. A., Egberink, H. F., Gonzales, J. L., Oreshkova, N., Broere, F., van der Poel, W. H. M., & Gerhards, N. M. (2023). Immune Responses and Pathogenesis following Experimental SARS-CoV-2 Infection in Domestic Cats. Viruses, 15(5), 1-18. Article 1052. [DOI] [Repository]
Vreman, S., Kik, M., Germeraad, E., Heutink, R., Harders, F., Spierenburg, M., Engelsma, M., Rijks, J., Brand, J. V. D., & Beerens, N. (2023). Zoonotic Mutation of Highly Pathogenic Avian Influenza H5N1 Virus Identified in the Brain of Multiple Wild Carnivore Species. FEMS Microbiology Immunology, 12(2), Article 168. [DOI] [Repository]
Vercammen, F., Cay, B., Gryseels, S., Balmelle, N., Joffrin, L., Van Hoorde, K., Verhaegen, B., Mathijs, E., Van Vredendaal, R., Dharmadhikari, T., Chiers, K., Van Olmen, T. J. S., Agliani, G., Van den Brand, J. M. A., & Leirs, H. (2023). SARS-CoV-2 Infection in Captive Hippos (Hippopotamus amphibius), Belgium. Animals, 13(2), 1-8. Article 316. [DOI] [Repository]
2022
Wetenschappelijke publicaties
Atama, N. C., Chestakova, I. V., de Bruin, E., van den Berg, T. J., Munger, E., Reusken, C., Oude Munnink, B. B., van der Jeugd, H., van den Brand, J. M. A., Koopmans, M. P. G., & Sikkema, R. S. (2022). Evaluation of the use of alternative sample types for mosquito-borne flavivirus surveillance: Using Usutu virus as a model. One Health, 15, 1-9. Article 100456. [DOI] [Repository]
Sikkema, R. S., Begeman, L., Janssen, R., Wolters, W. J., Geurtsvankessel, C., de Bruin, E., Hakze-van der Honing, R. W., Eblé, P., van der Poel, W. H. M., van den Brand, J. M. A., Slaterus, R., La Haye, M., Koopmans, M. P. G., Velkers, F., & Kuiken, T. (2022). Risks of SARS-CoV-2 transmission between free-ranging animals and captive mink in the Netherlands. Transboundary and emerging diseases, 69(6), 3339-3349. [DOI] [Repository]
van de Ven, K., Lanfermeijer, J., van Dijken, H., Muramatsu, H., Vilas Boas de Melo, C., Lenz, S., Peters, F., Beattie, M. B., Lin, P. J. C., Ferreira, J. A., van den Brand, J., van Baarle, D., Pardi, N., & de Jonge, J. (2022). A universal influenza mRNA vaccine candidate boosts T cell responses and reduces zoonotic influenza virus disease in ferrets. Science advances, 8(50). [DOI] [Repository]
Vilas Boas de Melo, C., Peters, F., van Dijken, H., Lenz, S., van de Ven, K., Wijsman, L., Gomersbach, A., Schouten, T., van Kasteren, P. B., van den Brand, J., & de Jonge, J. (2022). Influenza Infection in Ferrets with SARS-CoV-2 Infection History. Microbiology spectrum, 10(6), 1-15. Article e0138622. [DOI] [Repository]
Giglia, G., Mencattelli, G., Lepri, E., Agliani, G., Gobbi, M., Gröne, A., van den Brand, JM., Savini, G., & Mandara, M. T. (2022). West Nile Virus and Usutu Virus: A Post-Mortem Monitoring Study in Wild Birds from Rescue Centers, Central Italy. Viruses, 14(9), 1-9. Article 1994. [DOI] [Repository]
Giglia, G., Agliani, G., Lepri, E., Baldoni, E., Gobbi, M., Ceccherelli, R., Gröne, A., van den Brand, J. M. A., & Mandara, M. T. (2022). Neuronal satellitosis is a common finding in the avian brain. Avian Pathology, 51(4), 381-387. [DOI] [Repository]
Giglia, G., Agliani, G., Oude Munnik, B. B., Sikkema, R. S., Rijks, J., Koopmans, M. P. G., Reusken, C. B. E. M., Gröne, A., Mandara, M. T., & van den Brand, JM. (2022). Characterization of the Immunopathology of Usutu Virus-Associated Encephalitis: A Pilot Study in Naturally Infected Eurasian Blackbirds (Turdus Merula). Journal of Comparative Pathology, 191, 2-2. [DOI] [Repository]
Rosu, M. E., Kok, A., Bestebroer, T. M., de Meulder, D., Verveer, E. P., Pronk, M. R., Dekker, L. J. M., Luider, T. M., Richard, M., van den Brand, J. M. A., Fouchier, R. A. M., & Herfst, S. (2022). Contribution of neuraminidase to the efficacy of seasonal split influenza vaccines in the ferret model. Journal of Virology, 96(6), 1-18. Article e0195921. [DOI] [Repository]
Te, N., Ciurkiewicz, M., van den Brand, J. M. A., Rodon, J., Haverkamp, A.-K., Vergara-Alert, J., Bensaid, A., Haagmans, B. L., Baumgartner, W., & Segalés, J. (2022). Middle East respiratory syndrome coronavirus infection in camelids. Veterinary Pathology, 59(4), 546-555. [DOI]
Vakpublicaties
van den Brand, JM. (2022). Pathologie. In Proefdieren: zorg, kwaliteit en biotechniek (1 ed., Vol. 1, pp. 637-666).
van den Brand, JM. (2022). Secties. In Proefdieren: zorg, kwaliteit en biotechniek (1 ed., Vol. 1, pp. 619-636).
Populariserende publicaties
van den Brand, JM. (2022). Wilde vogels als informatiebron voor ziektebestrijding. In De Mug: Over steekmuggen en de verspreiding van ziekten (pp. 113-117)
2021
Wetenschappelijke publicaties
Giglia, G., Agliani, G., Munnink, B. B. O., Sikkema, R. S., Mandara, M. T., Lepri, E., Kik, M., Ijzer, J., Rijks, J. M., Fast, C., Koopmans, M. P. G., Verheije, M. H., Gröne, A., Reusken, C. B. E. M., & van den Brand, J. M. A. (2021). Pathology and Pathogenesis of Eurasian Blackbirds (Turdus merula) Naturally Infected with Usutu Virus. Viruses, 13(8), 1-16. Article 1481. [DOI] [Repository]
Watterson, D., Wijesundara, D. K., Modhiran, N., Mordant, F. L., Li, Z., Avumegah, M. S., McMillan, C. L., Lackenby, J., Guilfoyle, K., van Amerongen, G., Stittelaar, K., Cheung, S. T., Bibby, S., Daleris, M., Hoger, K., Gillard, M., Radunz, E., Jones, M. L., Hughes, K., ... Chappell, K. J. (2021). Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2. Clinical & translational immunology, 10(4), 1-21. Article e1269. [DOI] [Repository]
Mykytyn, A. Z., Lamers, M. M., Okba, N. M. A., Breugem, T. I., Schipper, D., van den Doel, P. B., van Run, P., van Amerongen, G., de Waal, L., Koopmans, M. P. G., Stittelaar, K. J., van den Brand, J. M. A., & Haagmans, B. L. (2021). Susceptibility of rabbits to SARS-CoV-2. Emerging Microbes and Infections, 10(1), 1-17. [DOI] [Repository]
2020
Wetenschappelijke publicaties
Okba, N. M. A., Widjaja, I., van Dieren, B., Aebischer, A., van Amerongen, G., de Waal, L., Stittelaar, K. J., Schipper, D., Martina, B., van den Brand, J. M. A., Beer, M., Bosch, B.-J., & Haagmans, B. L. (2020). Particulate multivalent presentation of the receptor binding domain induces protective immune responses against MERS-CoV. Emerging Microbes and Infections, 9(1), 1080-1091. [DOI] [Repository]
Stas, E., Kranenburg, L., Witt, P., de Grauw, J., van den Brand, J., Ensink, J., & Brommer, H. (2020). An atypical presentation of a mesenteric Meckel's diverticulum in a 7-year-old warmblood mare: case report. BMC Veterinary Research, 16(1), Article 409. [DOI] [Repository]
Ouwendijk, W. J., van den Ham, H. J., Delany, M. W., van Kampen, J. J., van Nierop, G. P., Mehraban, T., Zaaraoui-Boutahar, F., van IJcken, W. F., van den Brand, J. M., De Vries, R. D., Andeweg, A. C., & Verjans, G. M. (2020). Alveolar barrier disruption in varicella pneumonia is associated with neutrophil extracellular trap formation. JCI insight, 5(21), Article :e138900. [DOI] [Repository]
Herfst, S., Zhang, J., Richard, M., McBride, R., Lexmond, P., Bestebroer, T. M., Spronken, M. I. J., de Meulder, D., van den Brand, J. M., Rosu, M. E., Martin, S. R., Gamblin, S. J., Xiong, X., Peng, W., Bodewes, R., van der Vries, E., Osterhaus, A. D. M. E., Paulson, J. C., Skehel, J. J., & Fouchier, R. A. M. (2020). Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals. Cell Host & Microbe, 28(4), 602-613.e7. [DOI] [Repository]
Sikkema, R. S., Schrama, M., van den Berg, T., Morren, J., Munger, E., Krol, L., van der Beek, J. G., Blom, R., Chestakova, I., van der Linden, A., Boter, M., van Mastrigt, T., Molenkamp, R., Koenraadt, C. J., van den Brand, J. M., Oude Munnink, B. B., Koopmans, M. P., & van der Jeugd, H. (2020). Detection of West Nile virus in a common whitethroat (Curruca communis) and Culex mosquitoes in the Netherlands, 2020. Eurosurveillance, 25(40). [DOI] [Portal]
Jansen, A. J. G., Spaan, T., Low, H. Z., Di Iorio, D., van den Brand, J., Tieke, M., Barendrecht, A., Rohn, K., van Amerongen, G., Stittelaar, K., Baumgärtner, W., Osterhaus, A., Kuiken, T., Boons, G.-J., Huskens, J., Boes, M., Maas, C., & van der Vries, E. (2020). Influenza-induced thrombocytopenia is dependent on the subtype and sialoglycan receptor and increases with virus pathogenicity. Blood, 4(13), 2967-2978. [DOI] [Repository]
Rockx, B., Kuiken, T., Herfst, S., Bestebroer, T., Lamers, M. M., Munnink, B. B. O., de Meulder, D., van Amerongen, G., van den Brand, J., Okba, N. M. A., Schipper, D., van Run, P., Leijten, L., Sikkema, R., Verschoor, E., Verstrepen, B., Bogers, W., Langermans, J., Drosten, C., ... Haagmans, B. L. (2020). Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model. Science, 368(6494), 1012-1015. [DOI] [Repository]
Richard, M., van den Brand, J. M. A., Bestebroer, T. M., Lexmond, P., de Meulder, D., Fouchier, R. A. M., Lowen, A. C., & Herfst, S. (2020). Influenza A viruses are transmitted via the air from the nasal respiratory epithelium of ferrets. Nature Communications, 11(1), Article 766. [DOI] [Repository]
Giglia, G., Reusken, C. B. E. M., Schaafsma, F., Mandara, M. T., Rijks, J., Sikkema, R., Gröne, A., Koopmans, M., Verheije, M. H., & van den Brand, J. M. A. (2020). Usutu Virus Infection and Plasmodium Co-Infection in Blackbirds (Turdus Merula) in the Netherlands From 2016 to 2018. Journal of Comparative Pathology, 174, 155. [DOI] [Repository]
Begeman, L., Kooi, E. A., van Weezep, E., van de Bildt, M. W. G., Reusken, C. B. E. M., Lina, P. H. C., Koopmans, M. P. G., van den Brand, J. M. A., & Kuiken, T. (2020). Faeces as a novel material to estimate lyssavirus prevalence in bat populations. Zoonoses and Public Health, 67(2), 198-202. [DOI] [Repository]
Populariserende publicaties
van den Brand, JM. (2020, Nov). Vaccinonderzoek COVID-19. NVVP.
2019
Wetenschappelijke publicaties
Farag, E., Sikkema, R. S., Mohamedani, A. A., de Bruin, E., Munnink, B. B. O., Chandler, F., Kohl, R., van der Linden, A., Okba, N. M. A., Haagmans, B. L., van den Brand, J. M. A., Elhaj, A. M., Abakar, A. D., Nour, B. Y. M., Mohamed, A. M., Alwaseela, B. E., Ahmed, H., Alhajri, M. M., Koopmans, M., ... Elrahman, S. H. A. (2019). MERS-CoV in Camels but Not Camel Handlers, Sudan, 2015 and 2017. Emerging Infectious Diseases, 25(12), 2333-2335. [DOI] [Repository]
Petzold, J., van den Brand, J. M. A., Nobach, D., Hoffmann, B., Hoffmann, D., Fast, C., Reusken, C. B. E. M., van Run, P. R. W. A., Schlottau, K., Beer, M., & Herden, C. (2019). Distribution of zoonotic variegated squirrel bornavirus 1 in naturally infected variegated and Prevost's squirrels. Scientific Reports, 9(1), Article 11402. [DOI] [Repository]
Widagdo, W., Okba, N. M. A., Li, W., de Jong, A., de Swart, R. L., Begeman, L., van den Brand, J. M. A., Bosch, B.-J., & Haagmans, B. L. (2019). Species-Specific Colocalization of Middle East Respiratory Syndrome Coronavirus Attachment and Entry Receptors. Journal of Virology, 93(16). [DOI] [Repository]
Widagdo, W., Okba, N. M. A., Richard, M., de Meulder, D., Bestebroer, T. M., Lexmond, P., Farag, E. A. B. A., Al-Hajri, M., Stittelaar, K. J., de Waal, L., van Amerongen, G., van den Brand, J. M. A., Haagmans, B. L., & Herfst, S. (2019). Lack of Middle East Respiratory Syndrome Coronavirus Transmission in Rabbits. Viruses, 11(4), Article 381. [DOI] [Repository]
2018
Wetenschappelijke publicaties
van den Brand, JM. (2018). Distribution of zoonotic variegated squirrel bornavirus 1 in naturally infected variegated and Prevost's squirrels. Poster session presented at Veterinary science day 2018, Bunnik, Netherlands.
IJsseldijk, L. L., van Neer, A., Deaville, R., Begeman, L., van de Bildt, M., van den Brand, J. M. A., Brownlow, A., Czeck, R., Dabin, W., Ten Doeschate, M., Herder, V., Herr, H., IJzer, J., Jauniaux, T., Jensen, L. F., Jepson, P. D., Jo, W. K., Lakemeyer, J., Lehnert, K., ... Siebert, U. (2018). Beached bachelors: An extensive study on the largest recorded sperm whale Physeter macrocephalus mortality event in the North Sea. PLoS One, 13(8), Article e0201221. [DOI] [Repository]
Haverkamp, A.-K., Lehmbecker, A., Spitzbarth, I., Widagdo, W., Haagmans, B. L., Segalés, J., Vergara-Alert, J., Bensaid, A., van den Brand, J. M. A., Osterhaus, A. D. M. E., & Baumgärtner, W. (2018). Experimental infection of dromedaries with Middle East respiratory syndrome-Coronavirus is accompanied by massive ciliary loss and depletion of the cell surface receptor dipeptidyl peptidase 4. Scientific Reports, 8(1), Article 9778. [DOI] [Repository]
van den Brand, J. M. A., Verhagen, J. H., Veldhuis Kroeze, E. J. B., Van de Bildt, M. W. G., Bodewes, R., Herfst, S., Richard, M., Lexmond, P., Bestebroer, T. M., Fouchier, R. A. M., & Kuiken, T. (2018). Wild ducks excrete highly pathogenic avian influenza virus H5N8 (2014-2015) without clinical or pathological evidence of disease. Emerging Microbes and Infections, 7(1), 67. [DOI] [Repository]
de Wit, E., Siegers, J. Y., Cronin, J. M., Weatherman, S., van den Brand, J., Leijten, L. M., van Run, P. R., Begeman, L., van den Ham, H.-J., Andeweg, A. C., Bushmaker, T., Scott, D. P., Saturday, G., Vincent, M., Feldmann, H., & van Riel, D. (2018). 1918 H1N1 influenza virus replicates in the nervous system of ferrets. Journal of NeuroImmune Pharmacology, 13, S22-S22.
Poen, M. J., Bestebroer, T. M., Vuong, O., Scheuer, R. D., van der Jeugd, H. P., Kleyheeg, E., Eggink, D., Lexmond, P., van den Brand, J. M. A., Begeman, L., van der Vliet, S., Müskens, G. J. D. M., Majoor, F. A., Koopmans, M. P. G., Kuiken, T., & Fouchier, R. A. M. (2018). Local amplification of highly pathogenic avian influenza H5N8 viruses in wild birds in the Netherlands, 2016 to 2017. Eurosurveillance, 23(4), Article 17-00449. [DOI] [Repository]
Herfst, S., Mok, C. K. P., van den Brand, J. M. A., van der Vliet, S., Rosu, M. E., Spronken, M. I., Yang, Z., de Meulder, D., Lexmond, P., Bestebroer, T. M., Peiris, J. S. M., Fouchier, R. A. M., & Richard, M. (2018). Human Clade 2.3.4.4 A/H5N6 Influenza Virus Lacks Mammalian Adaptation Markers and Does Not Transmit via the Airborne Route between Ferrets. mSphere, 3(1), Article e00405-17. [DOI] [Repository]
Meyer Sauteur, P. M., de Groot, R. C. A., Estevão, S. C., Hoogenboezem, T., de Bruijn, A. C. J. M., Sluijter, M., de Bruijn, M. J. W., De Kleer, I. M., van Haperen, R., van den Brand, J. M. A., Bogaert, D., Fraaij, P. L. A., Vink, C., Hendriks, R. W., Samsom, J. N., Unger, W. W. J., & van Rossum, A. M. C. (2018). The Role of B Cells in Carriage and Clearance of Mycoplasma pneumoniae From the Respiratory Tract of Mice. Journal of Infectious Diseases, 217(2), 298-309. [DOI]
de Wit, E., Siegers, J. Y., Cronin, J. M., Weatherman, S., van den Brand, J., Leijten, L. M., van Run, P. R., Begeman, L., van den Ham, H.-J., Andeweg, A. C., Bushmaker, T., Scott, D. P., Saturday, G., Munster, V. J., Feldmann, H., & van Riel, D. (2018). 1918 H1N1 influenza virus replicates and induces pro-inflammatory cytokine responses in extra-respiratory tissues of ferrets. Journal of Infectious Diseases, 217(8), 1237-1246. [DOI]
2017
Wetenschappelijke publicaties
Jansen, G., Low, H., van den Brand, J., van Riel, D., & van der Vries, E. (2017). Uptake of Influenza Virus By Platelets Occurs Via Phagocytosis. Blood, 130.
Schlottau, K., Jenckel, M., van den Brand, J., Fast, C., Herden, C., Hoeper, D., Homeier-Bachmann, L., Thielebein, J., Mensing, N., Diender, B., Hoffmann, D., Ulrich, R. G., Mettenleiter, T. C., Koopmans, M., Tappe, D., Schmidt-Chanasit, J., Reusken, C. B. E. M., Beer, M., & Hoffmann, B. (2017). Variegated Squirrel Bornavirus 1 in Squirrels, Germany and the Netherlands. Emerging Infectious Diseases, 23(3), 477-481. [DOI]
Vergara-Alert, J., van den Brand, J. M. A., Widagdo, W., Muñoz, M., Raj, V. S., Schipper, D., Solanes, D., Cordón, I., Bensaid, A., Haagmans, B. L., & Segalés, J. (2017). Livestock Susceptibility to Infection with Middle East Respiratory Syndrome Coronavirus. Emerging Infectious Diseases, 23(2), 232-240. [DOI] [Repository]
Widagdo, W., Begeman, L., Schipper, D., van Run, P. R., Cunningham, A. A., Kley, N., Reusken, C. B. E. M., Haagmans, B. L., & van den Brand, J. M. A. (2017). Tissue Distribution of the MERS-Coronavirus Receptor in Bats. Scientific Reports, 7, Article 1193. [DOI] [Repository]
Richard, M., Herfst, S., van den Brand, J. M. A., de Meulder, D., Lexmond, P., Bestebroer, T. M., & Fouchier, R. A. M. (2017). Mutations Driving Airborne Transmission of A/H5N1 Virus in Mammals Cause Substantial Attenuation in Chickens only when combined. Scientific Reports, 7, Article 7187. [DOI] [Repository]
Short, K. R., Veeris, R., Leijten, L. M., van den Brand, J. M., Jong, V. L., Stittelaar, K. J., Osterhaus, A. D. M. E., Andeweg, A. C., & van Riel, D. (2017). Proinflammatory Cytokine Responses in Extra-Respiratory Tissues During Severe Influenza. Journal of Infectious Diseases, 216(7), 829-833. [DOI]
de Graaf, M., Bodewes, R., van Elk, C. E., van de Bildt, M., Getu, S., Aron, G. I., Verjans, G. M. G. M., Osterhaus, A. D. M. E., van den Brand, J. M. A., Kuiken, T., & Koopmans, M. P. G. (2017). Norovirus Infection in Harbor Porpoises. Emerging Infectious Diseases, 23(1), 87-91. [DOI] [Repository]
2016
Wetenschappelijke publicaties
Jansen, A. J. G., Low, H. Z., van den Brand, J., van Riel, D., Osterhaus, A., & van der Vries, E. (2016). Platelets Can Phagocytose Influenza Virus Which May Contribute to the Occurrence of Thrombocytopenia during Influenza Infection. Blood, 128(22). [DOI]
Raj, V. S., van den Brand, J. M. A., Volz, A., Wohlsein, P., Smits, S. L., Okba, N., Fux, R., Moise Bensaid, A., Solanes Foz, D., Kuiken, T., Baumgaertner, W., Segales, J., Sutter, G., Osterhaus, A. D. M. E., & Haagmans, B. L. (2016). A poxvirus-based vaccine reduces virus excretion after MERS coronavirus infection in dromedary camels. International Journal of Infectious Diseases, 45, 421-422. [DOI]
Haagmans, B. L., van den Brand, J. M. A., Raj, V. S., Volz, A., Wohlsein, P., Smits, S. L., Schipper, D., Bestebroer, T. M., Okba, N., Fux, R., Bensaid, A., Solanes Foz, D., Kuiken, T., Baumgärtner, W., Segalés, J., Sutter, G., & Osterhaus, A. D. M. E. (2016). An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels. Science, 351(6268), 77-81. [DOI]
Kühn, N., Bergmann, S., Kösterke, N., Lambertz, R. L. O., Keppner, A., van den Brand, J. M. A., Pöhlmann, S., Weiß, S., Hummler, E., Hatesuer, B., & Schughart, K. (2016). The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases. Journal of Virology, 90(9), 4298-307. [DOI]
Leist, S. R., Pilzner, C., van den Brand, J. M. A., Dengler, L., Geffers, R., Kuiken, T., Balling, R., Kollmus, H., & Schughart, K. (2016). Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice. BMC Genomics, 17, 143. [DOI]
Siegers, J. Y., van den Brand, J. M., Leijten, L. M., van de Bildt, M. W., van Run, P. R., Amerongen, G. V., Stittelaar, K. J., Koopmans, M. P. G., Osterhaus, A. D. M. E., Kuiken, T., & van Riel, D. (2016). Vaccination Is More Effective Than Prophylactic Oseltamivir in Preventing CNS Invasion by H5N1 Virus via the Olfactory Nerve. Journal of Infectious Diseases, 214(4), 516-24. [DOI]
van den Brand, J. M. A., Wohlsein, P., Herfst, S., Bodewes, R., Pfankuche, V. M., van de Bildt, M. W. G., Seehusen, F., Puff, C., Richard, M., Siebert, U., Lehnert, K., Bestebroer, T., Lexmond, P., Fouchier, R. A. M., Prenger-Berninghoff, E., Herbst, W., Koopmans, M., Osterhaus, A. D. M. E., Kuiken, T., & Baumgärtner, W. (2016). Influenza A (H10N7) Virus Causes Respiratory Tract Disease in Harbor Seals and Ferrets. PLoS One, 11(7), Article e0159625. [DOI] [Repository]
2015
Wetenschappelijke publicaties
van den Brand, J. M. A., Smits, S. L., & Haagmans, B. L. (2015). Pathogenesis of Middle East respiratory syndrome coronavirus. Journal of Pathology, 235(2), 175-84. [DOI]
Haagmans, B. L., van den Brand, J. M. A., Provacia, L. B., Raj, V. S., Stittelaar, K. J., Getu, S., de Waal, L., Bestebroer, T. M., Amerongen, G. V., Verjans, G. M. G. M., Fouchier, R. A. M., Smits, S. L., Kuiken, T., & Osterhaus, A. D. M. E. (2015). Asymptomatic Middle East respiratory syndrome coronavirus infection in rabbits. Journal of Virology, 89(11), 6131-5. [DOI]
van den Brand, J. M., Krone, O., Wolf, P. U., Van de Bildt, M. W. G., Amerongen, G. V., Osterhaus, A. D. M. E., & Kuiken, T. (2015). Host-specific exposure and fatal neurologic disease in wild raptors from highly pathogenic avian influenza virus H5N1 during the 2006 outbreak in Germany. Veterinary Research, 46, 24. [DOI]
Richard, M., Herfst, S., van den Brand, J. M. A., Lexmond, P., Bestebroer, T. M., Rimmelzwaan, G. F., Koopmans, M. P. G., Kuiken, T., & Fouchier, R. A. M. (2015). Low Virulence and Lack of Airborne Transmission of the Dutch Highly Pathogenic Avian Influenza Virus H5N8 in Ferrets. PLoS One, 10(6), e0129827. [DOI]
Drexler, J. F., Corman, V. M., Lukashev, A. N., van den Brand, J. M. A., Gmyl, A. P., Brünink, S., Rasche, A., Seggewiβ, N., Feng, H., Leijten, L. M., Vallo, P., Kuiken, T., Dotzauer, A., Ulrich, R. G., Lemon, S. M., Drosten, C., & Hepatovirus Ecology Consortium (2015). Evolutionary origins of hepatitis A virus in small mammals. Proceedings of the National Academy of Sciences of the United States of America, 112(49), 15190-5. [DOI]
Short, K. R., Richard, M., Verhagen, J. H., van Riel, D., Schrauwen, E. J. A., van den Brand, J. M. A., Mänz, B., Bodewes, R., & Herfst, S. (2015). One health, multiple challenges: The inter-species transmission of influenza A virus. Health, 1, 1-13. [DOI] [Repository]
2014
Wetenschappelijke publicaties
van den Brand, J. M. A., Haagmans, B. L., van Riel, D., Osterhaus, A. D. M. E., & Kuiken, T. (2014). The pathology and pathogenesis of experimental severe acute respiratory syndrome and influenza in animal models. Journal of Comparative Pathology, 151(1), 83-112. [DOI] [Repository]
Goeijenbier, M., van Gorp, E. C. M., Van den Brand, J. M. A., Stittelaar, K. J., Bakhtiari, K., Roelofs, J. J. T. H., Amerongen, G. V., Kuiken, T., Martina, B. E. E., Meijers, J. C. M., & Osterhaus, A. D. M. E. (2014). Activation of coagulation and tissue fibrin deposition in experimental influenza in ferrets. BMC Microbiology, 14, 134. [DOI]
Bodewes, R., Ruiz-Gonzalez, A., Schapendonk, C. M. E., van den Brand, J. M. A., Osterhaus, A. D. M. E., & Smits, S. L. (2014). Viral metagenomic analysis of feces of wild small carnivores. Virology Journal, 11, 89. [DOI]
Raj, V. S., Smits, S. L., Provacia, L. B., van den Brand, J. M. A., Wiersma, L., Ouwendijk, W. J. D., Bestebroer, T. M., Spronken, M. I., van Amerongen, G., Rottier, P. J. M., Fouchier, R. A. M., Bosch, B. J., Osterhaus, A. D. M. E., & Haagmans, B. L. (2014). Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus. Journal of Virology, 88(3), 1834-8. [DOI] [Repository]
2013
Wetenschappelijke publicaties
Goeijenbier, M., Van den Brand, J. M. A., Stittelaar, K., Van Haagen, C., Bakhtiari, K., Kuiken, T., Osterhaus, A. D. M. E., Martina, B. E., Meijers, J. C., & Van Gorp, E. C. M. (2013). Consumptive coagulopathy and tissue fibrin deposition in seasonal-, pandemic- and highly pathogenic avian influenza infection. Journal of Thrombosis and Haemostasis, 11, 239-239.
Richard, M., Schrauwen, E. J. A., de Graaf, M., Bestebroer, T. M., Spronken, M. I. J., van Boheemen, S., de Meulder, D., Lexmond, P., Linster, M., Herfst, S., Smith, D. J., van den Brand, J. M., Burke, D. F., Kuiken, T., Rimmelzwaan, G. F., Osterhaus, A. D. M. E., & Fouchier, R. A. M. (2013). Limited airborne transmission of H7N9 influenza A virus between ferrets. Nature, 501(7468), 560-3. [DOI]
2012
Wetenschappelijke publicaties
van den Brand, J. M. A., van Leeuwen, M., Schapendonk, C. M., Simon, J. H., Haagmans, B. L., Osterhaus, A. D. M. E., & Smits, S. L. (2012). Metagenomic analysis of the viral flora of pine marten and European badger feces. Journal of Virology, 86(4), 2360-5. [DOI]
van den Brand, J. M. A., Stittelaar, K. J., Leijten, L. M. E., van Amerongen, G., Simon, J. H., Osterhaus, A. D. M. E., & Kuiken, T. (2012). Modification of the ferret model for pneumonia from seasonal human influenza A virus infection. Veterinary Pathology, 49(3), 562-8. [DOI]
van den Brand, J. M. A., Stittelaar, K. J., Amerongen, G. V., Reperant, L. A., de Waal, L., Osterhaus, A. D. M. E., & Kuiken, T. (2012). Comparison of temporal and spatial dynamics of seasonal H3N2, pandemic H1N1 and highly pathogenic avian influenza H5N1 virus infections in ferrets. PLoS One, 7(8), e42343. [DOI]
2011
Wetenschappelijke publicaties
Kuiken, T., Fouchier, R. A. M., Rimmelzwaan, G. F., van den Brand, JM., van Riel, D., & Osterhaus, A. (2011). Pigs, Poultry, and Pandemic Influenza: How Zoonotic Pathogens Threaten Human Health. Advances in Experimental Medicine and Biology, 719, 59-66. Article 719. [DOI]
Smits, S. L., van den Brand, J. M. A., de Lang, A., Leijten, L. M. E., van IJcken, W. F. J., Amerongen, G. V., Osterhaus, A. D. M. E., Andeweg, A. C., & Haagmans, B. L. (2011). Distinct severe acute respiratory syndrome coronavirus-induced acute lung injury pathways in two different nonhuman primate species. Journal of Virology, 85(9), 4234-45. [DOI]
Baras, B., de Waal, L., Stittelaar, K. J., Jacob, V., Giannini, S., Kroeze, E. J. B. V., van den Brand, J. M. A., Amerongen, G. V., Simon, J. H., Hanon, E., Mossman, S. P., & Osterhaus, A. D. M. E. (2011). Pandemic H1N1 vaccine requires the use of an adjuvant to protect against challenge in naïve ferrets. Vaccine, 29(11), 2120-6. [DOI]
van den Brand, J. M. A., Kreijtz, J. H. C. M., Bodewes, R., Stittelaar, K. J., van Amerongen, G., Kuiken, T., Simon, J., Fouchier, R. A. M., Del Giudice, G., Rappuoli, R., Rimmelzwaan, G. F., & Osterhaus, A. D. M. E. (2011). Efficacy of vaccination with different combinations of MF59-adjuvanted and nonadjuvanted seasonal and pandemic influenza vaccines against pandemic H1N1 (2009) influenza virus infection in ferrets. Journal of Virology, 85(6), 2851-8. [DOI]
2010
Wetenschappelijke publicaties
Van Den Brand, J., Stittelaar, K., Herfst, S., Van De Bildt, M., Kuiken, T., & Osterhaus, A. (2010). Pathology of Pandemic (h1n1) 2009 Influenza Virus Infection in Macaques, Ferrets and Cats. Journal of Comparative Pathology, 143(4), 346-346. [DOI]
Kuiken, T., van den Brand, J., van Riel, D., Pantin-Jackwood, M., & Swayne, D. E. (2010). Comparative Pathology of Select Agent Influenza A Virus Infections. Veterinary Pathology, 47(5), 893-914. [DOI]
Smits, S. L., de Lang, A., van den Brand, J. M. A., Leijten, L. M., van IJcken, W. F. J., Eijkemans, M. J. C., Amerongen, G. V., Kuiken, T., Andeweg, A. C., Osterhaus, A. D. M. E., & Haagmans, B. L. (2010). Exacerbated innate host response to SARS-CoV in aged non-human primates. PLoS Pathogens, 6(2), e1000756. [DOI] [Repository]
van den Brand, J. M. A., Stittelaar, K. J., Amerongen, G. V., Rimmelzwaan, G. F., Simon, J., de Wit, E., Munster, V. J., Bestebroer, T. M., Fouchier, R. A. M., Kuiken, T., & Osterhaus, A. D. M. E. (2010). Severity of pneumonia due to new H1N1 influenza virus in ferrets is intermediate between that due to seasonal H1N1 virus and highly pathogenic avian influenza H5N1 virus. Journal of Infectious Diseases, 201(7), 993-9. [DOI]
Chutinimitkul, S., van Riel, D., Munster, V. J., van den Brand, J. M. A., Rimmelzwaan, G. F., Kuiken, T., Osterhaus, A. D. M. E., Fouchier, R. A. M., & de Wit, E. (2010). In vitro assessment of attachment pattern and replication efficiency of H5N1 influenza A viruses with altered receptor specificity. Journal of Virology, 84(13), 6825-33. [DOI]
Munster, V. J., Schrauwen, E. J. A., de Wit, E., van den Brand, J. M. A., Bestebroer, T. M., Herfst, S., Rimmelzwaan, G. F., Osterhaus, A. D. M. E., & Fouchier, R. A. M. (2010). Insertion of a multibasic cleavage motif into the hemagglutinin of a low-pathogenic avian influenza H6N1 virus induces a highly pathogenic phenotype. Journal of Virology, 84(16), 7953-60. [DOI]
Herfst, S., van den Brand, J. M. A., Schrauwen, E. J. A., de Wit, E., van Munster, J., van Amerongen, G., Linster, M., Zaaraoui-Boutahar, F., van IJcken, W. F. J., Rimmelzwaan, G. F., Osterhaus, A. D. M. E., Fouchier, R. A. M., Andeweg, A. C., & Kuiken, T. (2010). Pandemic 2009 H1N1 influenza virus causes diffuse alveolar damage in cynomolgus macaques. Veterinary Pathology, 47(6), 1040-7. [DOI]
van den Brand, J. M. A., Stittelaar, K. J., Amerongen, G. V., Van de Bildt, M. W. G., Leijten, L. M. E., Kuiken, T., & Osterhaus, A. D. M. E. (2010). Experimental pandemic (H1N1) 2009 virus infection of cats. Emerging Infectious Diseases, 16(11), 1745-7. [DOI]
Bodewes, R., Kreijtz, J. H. C. M., van Amerongen, G., Geelhoed-Mieras, M. M., Verburgh, R. J., Heldens, J. G. M., Bedwell, J., van den Brand, J. M. A., Kuiken, T., van Baalen, C. A., Fouchier, R. A. M., Osterhaus, A. D. M. E., & Rimmelzwaan, G. F. (2010). A single immunization with CoVaccine HT-adjuvanted H5N1 influenza virus vaccine induces protective cellular and humoral immune responses in ferrets. Journal of Virology, 84(16), 7943-52. [DOI]
2009
Wetenschappelijke publicaties
Rockx, B., Baas, T., Zornetzer, G. A., Haagmans, B., Sheahan, T., Frieman, M., Dyer, M. D., Teal, T. H., Proll, S., van den Brand, J., Baric, R., & Katze, M. G. (2009). Early Upregulation of Acute Respiratory Distress Syndrome-Associated Cytokines Promotes Lethal Disease in an Aged-Mouse Model of Severe Acute Respiratory Syndrome Coronavirus Infection (vol 83, pg 7062, 2009). Journal of Virology, 83(17), 9022-9022. [DOI]
Rockx, B., Baas, T., Zornetzer, G. A., Haagmans, B., Sheahan, T., Frieman, M., Dyer, M. D., Teal, T. H., Proll, S., van den Brand, J., Baric, R., & Katze, M. G. (2009). Early Upregulation of Acute Respiratory Distress Syndrome-Associated Cytokines Promotes Lethal Disease in an Aged-Mouse Model of Severe Acute Respiratory Syndrome Coronavirus Infection. Journal of Virology, 83(14), 7062-7074. [DOI]
Kreijtz, J. H. C. M., Suezer, Y., de Mutsert, G., van den Brand, J. M. A., van Amerongen, G., Schnierle, B. S., Kuiken, T., Fouchier, R. A. M., Löwer, J., Osterhaus, A. D. M. E., Sutter, G., & Rimmelzwaan, G. F. (2009). Recombinant modified vaccinia virus Ankara expressing the hemagglutinin gene confers protection against homologous and heterologous H5N1 influenza virus infections in macaques. Journal of Infectious Diseases, 199(3), 405-13. [DOI]
van Riel, D., van den Brand, J. M. A., van Munster, J., Besteboer, T. M., Fouchier, R. A. M., Osterhaus, A. D. M. E., & Kuiken, T. (2009). Pathology and virus distribution in chickens naturally infected with highly pathogenic avian influenza A virus (H7N7) During the 2003 outbreak in The Netherlands. Veterinary Pathology, 46(5), 971-6. [DOI]
Munster, V. J., de Wit, E., van den Brand, J. M. A., Herfst, S., Schrauwen, E. J. A., Bestebroer, T. M., van de Vijver, D. A. M. C., Boucher, C. A. B., Koopmans, M. P. G., Rimmelzwaan, G. F., Kuiken, T., Osterhaus, A. D. M. E., & Fouchier, R. A. M. (2009). Pathogenesis and transmission of swine-origin 2009 A(H1N1) influenza virus in ferrets. Science, 325(5939), 481-3. [DOI]
Kreijtz, J. H. C. M., Suezer, Y., de Mutsert, G., van den Brand, J. M. A., van Amerongen, G., Schnierle, B. S., Kuiken, T., Fouchier, R. A. M., Löwer, J., Osterhaus, A. D. M. E., Sutter, G., & Rimmelzwaan, G. F. (2009). Preclinical evaluation of a modified vaccinia virus Ankara (MVA)-based vaccine against influenza A/H5N1 viruses. Vaccine, 27(45), 6296-9. [DOI]
Kreijtz, J. H. C. M., Suezer, Y., de Mutsert, G., Amerongen, G. V., Schwantes, A., van den Brand, J. M. A., Fouchier, R. A. M., Löwer, J., Osterhaus, A. D. M. E., Sutter, G., & Rimmelzwaan, G. F. (2009). MVA-based H5N1 vaccine affords cross-clade protection in mice against influenza A/H5N1 viruses at low doses and after single immunization. PLoS One, 4(11), e7790. [DOI]
Bodewes, R., Kreijtz, J. H. C. M., Baas, C., Geelhoed-Mieras, M. M., de Mutsert, G., van Amerongen, G., Fouchier, R. A. M., Osterhaus, A. D. M. E., Rimmelzwaan, G. F., & van den Brand, JM. (2009). Vaccination against human influenza A/H3N2 virus prevents the induction of heterosubtypic immunity against lethal infection with avian influenza A/H5N1 virus. PLoS One, 4(5), e5538. [DOI]
Kreijtz, J. H. C. M., Bodewes, R., van den Brand, J. M. A., de Mutsert, G., Baas, C., van Amerongen, G., Fouchier, R. A. M., Osterhaus, A. D. M. E., & Rimmelzwaan, G. F. (2009). Infection of mice with a human influenza A/H3N2 virus induces protective immunity against lethal infection with influenza A/H5N1 virus. Vaccine, 27(36), 4983-9. [DOI]
2008
Wetenschappelijke publicaties
Haagmans, B. L., Smits, S. L., de Lang, A., van den Brand, J. M. A., Leijten, L. M. E., Andeweg, A., van Amerongen, G., Kuiken, T., & Osterhaus, A. D. M. E. (2008). Severe SARS coronavirus infection in aged macaques is associated with reduced expression of anti-inflammatory type-1 interferons. Cytokine, 43(3), 243-243. [DOI]
van den Brand, J. M. A., Haagmans, B. L., Leijten, L. M. E., van Riel, D., Martina, B. E. E., Osterhaus, A. D. M. E., & Kuiken, T. (2008). Pathology of experimental SARS coronavirus infection in cats and ferrets. Veterinary Pathology, 45(4), 551-62. [DOI]
2007
Wetenschappelijke publicaties
de Bruijn, N. D., Kirpensteijn, J., Neyens, I. J. S., Van den Brand, J. M. A., & van den Ingh, T. S. G. A. M. (2007). A clinicopathological study of 52 feline epulides. Veterinary Pathology, 44(2), 161-9. [DOI]
van den Brand, J. M. A., Manvell, R., Paul, G., Kik, M. J. L., & Dorrestein, G. M. (2007). Reovirus infections associated with high mortality in psittaciformes in The Netherlands. Avian Pathology, 36(4), 293-9. [DOI]
2006
Wetenschappelijke publicaties
van den Brand, J. M. A., Hendriks - Onstein, W. K., Kik, M. J. L., Gröne, A., Sloet van Oldruitenborgh-Oosterbaan, M. M., & van den Brand, JM. (2006). Renal cysts, nephrolithiasis, and ovarian cysts in a donkey suspected of having been sexually abused. Tijdschrift voor Diergeneeskunde, 15(131), 730-735.