From September 1995 I have worked as a post-doc in the Neuroimaging section of the Department of psychiatry of the University Medical Center Utrecht, and from 1998 onwards as an assistant professor. During the first years, I developed the image processing and analysis system of the group. As of 2015, thousands of scans have been analyzed using this pipeline. Gradually my research interests moved from image analysis of structural MRI brain scans to (longitudinal) brain data analysis and modeling, and from group-level statistics to individual predictions using Machine Learning. My research involves the study of both healthy development and psychiatric disorders including schizophrenia and bipolar disorder. Currently, the focus of my research line is on developing individual prediction models based on MRI brain image data and clinical data from psychiatric patients, with special attention to interpretable models. Starting in 2016, part of my research and teaching activities is at the Faculty of Humanities of Utrecht University.