Publications (in reverse chronological order)


385   Gonsalves, N., M.K. Sun, P. Chopra, C.-F. Latchoumane, S. Bajwa, R. Tang, B. Patel, G.J. Boons.and L. Karumbaiah. 2024. Neuritogenic glycosaminoglycan hydrogels promote functional recovery after severe traumatic brain injury. J. Neural Eng., In press (DOI: 10.1088/1741-2552/ad5108, online 28/May/2024).

preprint     Tomris, I., A. Kimpel, R. Liang, R. van der Woude, G.J. Boons, Z. Li, and R.P. de Vries. 2024. The HCoV-HKU1 N-terminal domain binds a wide range of 9-O-acetylated sialic acids presented on different glycan cores. bioRxvi (DOI: 10.1101/2024.05.24.595699, posted 24/May/2024).

384   Li, T., C.M. Spruit, N. Wei, L. Liu, M.A. Wolfert, R.P. de Vries, and G.J. Boons. 2024. Chemoenzymatic synthesis of tri-antennary N-glycans terminating in sialyl-Lewisx reveals the importance of glycan complexity for influenza A virus receptor binding. Chem. Eur. J.: e202401108, In press (DOI: 10.1002/chem.202401108).

383   Verpalen, E.C.J.M., A.J. Brouwer,M.A. Wolfert, and G.J. Boons. 2024. Structure-based design and synthesis of lipid A derivatives to modulate cytokine responses. Chem. Eur. J.: e202400429, In press (DOI: 10.1002/chem.202400429).

382   Vigeveno, R.M., A.X. Han, R.P. de Vries, E. Parker, K. de Haan, S. van Leeuwen, K.D. Hulme, A.S. Lauring, A.J.W. te Velthuis, G.J. Boons, R.A.M. Fouchier, C.A. Russell, M.D. de Jong, and D. Eggink. 2024. Long-term evolution of human seasonal influenza virus A(H3N2) is associated with an increase in polymerase complex activity. Virus Evolution 10(1): veae030.

381   Filius, M., R. van Wee, C. de Lannoy, I. Westerlaken, Z. Li, S.H. Kim, C. de Agrela Pinto, Y. Wu, G.J. Boons, M. Pabst, D. de Ridder, and C. Joo. 2024. Full-length single-molecule protein fingerprinting. Nat. Nanotechnol. 19(5): 652-659.

380   Spruit, C.M., D.I. Palme, T. Li, M. Ríos Carrasco, A. Gabarroca García, I.R. Sweet, M. Kuryshko, J.C.L. Maliepaard, K.R. Reiding, D. Scheibner, G.J. Boons, E.M. Abdelwhab, and R.P. de Vries. 2024. Complex N-glycans are important for interspecies transmission of H7 influenza A viruses. J. Virol. 98(4): e0194123. Selected as Editor's Pick.

379   Unione, L., A.N.A. Ammerlaan, G.P. Bosman, E. Uslu, R. Liang, F. Broszeit, R. van der Woude, Y. Liu, S. Ma, L. Liu, M. Gomez-Redondo, I.A. Bermejo, P. Valverde, T. Diercks, A. Ardá, R.P. de Vries, and G.J. Boons. 2024. Probing altered receptor specificities of antigenically drifting human H3N2 viruses by chemoenzymatic synthesis, NMR, and modeling.

378   Wu, Y., G.P. Bosman, D. Chapla, C. Huang, K.W. Moremen, R.P. de Vries, and G.J. Boons. 2024. A biomimetic synthetic strategy can provide keratan sulfate I and II oligosaccharides with diverse fucosylation and sulfation patterns. J. Am. Chem. Soc. 146(13): 9230-9240.

377   Joshi, A., P. Chopra, A. Venot, and G.J. Boons. 2024. Chemical synthesis of D-4,5 unsaturated heparan sulfate oligosaccharides for biomarker discovery. Org. Lett26(12): 2462-2466

376    Ma, S., L. Liu, D. Eggink, S. Herfst, R.A.M. Fouchier, R.P. de Vries, G.J. Boons. 2024. Asymmetrical bi-antennary glycans prepared by a Stop-and-Go strategy reveal receptor binding evolution of human influenza A viruses. JACS Au 4(2): 607-618. Featured as an ACS Editors' Choice.

375   Vos, G.M., Y. Wu, R. van der Woude, R.P. de Vries, and G.J. Boons. 2024. Chemo-enzymatic synthesis of isomeric I-branched polylactosamines using traceless blocking groups. Chem. Eur. J. 30(5): e202302877.

374   de Jong, S.P.J., Z.C. Felix Garza, J.C. Gibson, S. van Leeuwen, R.P. de Vries, G.J. Boons, M. van Hoesel, K. de Haan, L.E. van Groeningen, K.D. Hulme, H.D.G. van Willigen, E. Wynberg, G.J. de Bree, A. Matser, M. Bakker, L. van der Hoek, M. Prins, N.A. Kootstra, D. Eggink, B.E. Nichols, A.X. Han, M.D. de Jong, and C.A. Russell. 2024. Determinants of epidemic size and the impacts of lulls in seasonal influenza virus circulation. Nat. Commun. 15(1): 591.

373   Bunyatov, M., M.A. Wolfert, R. Huizinga, M. Schreurs, B.C. Jacobs, and G.J. Boons. 2024. Chemoenzymatic synthesis of human natural killer-1 containing glycans and application as serum antibodies probes. Nat. Synth. 3: 85-98. Featured in a Nat. Synth. Research Briefing.

research briefing        Jacobs, B.C. and G.J. Boons. 2024. Synthetic glycans provide insight in binding properties of toxic serum antibodies. Nat. Synth. 3: 15-16.


372   Pronker, M.F., R. Creutznacher, I. Drulyte, R.J.G. Hulswit, Z. Li, F.J.M. van Kuppeveld, J. Snijder, Y. Lang, B.-J. Bosch, G.J. Boons, M. Frank, R.J. de Groot, and D.L. Hurdiss. 2023. Sialoglycan binding triggers spike opening in a human coronavirus. Nature 624(7990): 201-206.

371   Wu, Y., G.M. Vos, C. Huang, D. Chapla, A.L.M. Kimpel, K.W. Moremen, R.P. de Vries, and G.J. Boons. 2023. Exploiting substrate specificities of 6-O-sulfotransferases to enzymatically synthesize keratan sulfate oligosaccharides. JACS Au 3(11): 3155-3164. Selected for front cover picture.

370   Spruit, C.M., I.R. Sweet, J.C.L. Maliepaard, T. Bestebroer, P. Lexmond, B Qiu, M.J.A. Damen, R.A.M. Fouchier, K.R. Reiding, J. Snijder, S. Herfst, G.J. Boons, and R.P. de Vries. 2023. Contemporary human H3N2 influenza A viruses require a low threshold of suitable glycan receptors for efficient infection. Glycobiology 33(10): 784-800.

369   Vos, G.M., K.C. Hooijschuur, Z. Li, J. Fjeldsted, C. Klein, R.P. de Vries, J. Sastre Toraño, and G.J. Boons. 2023. Sialic acid O-acetylation patterns and glycosidic linkage type determination by ion mobility-mass spectrometry. Nat. Commun. 14(1): 6795.

368   Chopra, P., T. Yadavalli, F. Palmieri, S.A.K. Jongkees, L. Unione, D. Shukla, and G.J. Boons. 2023. Synthetic heparanase inhibitors can prevent herpes simplex viral spread. Angew. Chem. Int. Ed. 62(41): e202309838.

367   Kadirvelraj, R., B.M. Boruah, S. Wang, D. Chapla, C. Huang, A. Ramiah, K.L. Hudson, A.R. Prudden, G.J. Boons, S.G. Withers, Z.A. Wood, and K.W. Moremen. 2023. Structural basis for Lewis antigen synthesis by the alpha1,3-fucosyltransferase, FUT9. Nat. Chem. Biol. 19(8): 1022-1030.

366   Maliepaard, J.C.L., J.M.A. Damen, G.J.P.H. Boons, and K.R. Reiding. 2023. Glycoproteomics-compatible MS/MS-based quantification of glycopeptide isomers. Anal. Chem. 95(25): 9605-9614.

365   Vos, G.M., J. Weber, I.R. Sweet, K.C. Hooijschuur, J. Sastre Toraño, and G.J. Boons. 2023. Oxidative release of O-glycans under neutral conditions for analysis of glycoconjugates having base-sensitive substituents. Anal. Chem. 95(23): 8825-8833.

364   Xia, M., F. Vago, L. Han, P. Huang, L. Nguyen, G.J. Boons, J.S Klassen, W. Jiang, and M. Tan. 2023. The aTSR domain of Plasmodium circumsporocite protein bound heparan sulfates and elicited high titers of sporozoite binding antibody after displayed by nanoparticles. Int. J. Nanomed.: 3087-3107.

363   Perrett, H.R., P.J.M. Brouwer, J. Hurtado, M.L. Newby, L. Liu, H. Müller-Kräuter, S. Müller Aguirre, J.A. Burger, J.H. Bouhuijs, G. Gibson, T. Messmer, J.S. Schieffelin, A. Antanasijevic, G.J. Boons, T. Strecker, M. Crispin, R.W. Sanders, B. Briney, and A.B. Ward. 2023. Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies. Cell Rep. 42(5): 112524.

362   Hamming, P.H.E., N.J. Overeem, K. Diestelhorst, T. Fiers, M. Tieke, G.M. Vos, G.J.P.H. Boons, E. van der Vries, S. Block, and J. Huskens. 2023. Receptor density-dependent motility of influenza virus particles on surface gradients. ACS Appl. Mater. Interfaces 15(20): 25066-25076.

361   Tomris, I., L. Unione, L. Nguyen, P. Zaree, K.M. Bouwman, L. Liu, Z. Li, J.A. Fok, M. Ríos Carrasco, R. van der Woude, A.L.M. Kimpel, M.W. Linthorst, S.A. Kilavuzoglu, E.C.J.M Verpalen, T.G. Caniels, R.W. Sanders, B.A. Heesters, R.J. Pieters, J. Jiménez-Barbero, J.S. Klassen, G.J. Boons, and R.P. de Vries. 2023. SARS-CoV-2 spike N-terminal domain engages 9-O-acetylated a2–8-linked sialic acids. ACS Chem. Biol. 18(5): 1180-1191.

360   Chen, D., A.K. Srivastava, J. Dubrochowska, L. Liu, T. Li, J.P. Hoffmann, J.K. Kolls, and G.J. Boons. 2023. A bioactive synthetic outer-core oligosaccharide derived from a Klebsiella pneumonia lipopolysaccharide for bacteria recognition. Chem. Eur. J. 29(25): e202203408.

359   Riedel, J., M. Lettow, M. Grabarics, M Gotze, R.L. Miller, G.J. Boons, G. Meijer, G. von Helden, G.P. Szekeres, and K. Pagel. 2023. Predicting structural motifs of glycosaminoglycans using cryogenic infrared spectroscopy and random forest. J. Am. Chem. Soc. 145(14): 7859-7868.

358   Sun, L., P. Chopra, I. Tomris, R. van der Woude, L. Liu, R.P. de Vries, and G.J. Boons. 2023. Well-defined heparin mimetics can inhibit binding of the trimeric spike of SARS-CoV-2 in a length dependent manner. JACS Au 3(4): 1185-1195.

357   Canales, A., J. Sastre, J.M. Ordun~a, C.M. Spruit, J. Pe´rez-Castells, G. Domi´nguez, K.M. Bouwman, R. van der Woude, F.J. Can~ada, C.M. Nycholat, J.C. Paulson, G.J. Boons, J. Jime´nez-Barbero, and R.P. de Vries. 2023. Revealing the specificity of human H1 influenza A viruses to complex N-glycans. JACS Au 3(3): 868-878.

preprint        Saito-Diaz, K., P. Dietrich, H.-F. Wu, X. Sun, A. Jayesh Patel, C. Gale Wzientek, A.R. Prudden, G.J. Boons, S. Chen, L. Studer, B. Xu, I. Dragatsis, and N. Zeltner. 2023. Genipin crosslinks the extracellular matrix to rescue developmental and degenerative defects, and accelerates regeneration of peripheral neurons. bioRxiv (DOI: 10.1101/2023.03.22.533831, posted 24/Mar/2023).

356   Scheibner, D., A.H. Salaheldin, O. Bagato, L.M. Zaeck, A. Mostafa, U. Blohm, C. Mu¨ller, A.F. Eweas, K. Franzke, A. Karger, A. Schäfer, M. Gischke, D. Hoffmann, S. Lerolle, X. Li, H.S. Abd El-Hamid, J. Veits, A. Breithaupt, G.J. Boons, M. Matrosovich, S. Finke, S. Pleschka, T.C. Mettenleiter, R.P. de Vries, and E.M. Abdelwhab. 2023. Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses. PLoS Path. 9(2): e1011135.


355   Sun, L., P. Chopra, and G.J. Boons. 2022. Chemoenzymatic synthesis of heparan sulfate oligosaccharides having a domain structure. Angew. Chem. Int. Ed. 61(47): e202211112.

354   Trattnig, N., Z. Li, G. Bosman, P. Kosma, and G.J. Boons. 2022. Site-specific multi-functionalization of the carrier protein CRM197 by disulfide rebridging for glycoconjugate vaccine development. ChemBioChem 23(21): e202200408.

353   de Jong, H., M.J. Moure, J.E.M. Hartman, G.P. Bosman, J.Y. Ong, B.W. Bardoel, G.J. Boons, M.M.S.M. Wösten, and T. Wennekes. 2022. Selective exoenzymatic labeling of lipooligosaccharides of Neisseria gonorrhoeae with a2,6-sialoside analogues. ChemBioChem 23(19): e202200340.

352   Verheyen S, J. Blatterer J, M.R. Speicher, G.S. Bhavani, G.J. Boons, M.B. Ilse, D. Andrae, J. Sproß, F.M. Vaz, S.G. Kircher, L. Posch-Pertl, D. Baumgartner, T. Lu¨bke, H. Shah, A. Al Kaissi, K.M. Girisha, and B. Plecko. 2022. Novel subtype of mucopolysaccharidosis caused by arylsulfatase K (ARSK) deficiency. J. Med. Gen. 59(10): 957-964.

351   Kariyawasam, U., M. Gulati, Y. Wang, H. Bao, T. Shan, X. Li, X. Cao, N. Sumathipale, Y. Hu, X. Zhang, G.J. Boons, and H. Jiang. 2022. Preferential binding of DAP-PGs by major peptidoglycan recognition proteins found in cell-free hemolymph of Manduca sexta. Insect Biochem. Mol. Biol. 148: 103827.

350   Li, Z., R. Derking, W.-H. Lee, G.P. Bosman, A.B. Ward, R.W. Sanders, and G.J. Boons. 2022. Conjugation of a Toll-like receptor agonist to glycans of an HIV native-like envelope trimer preserves neutralization epitopes. ChemBioChem 23(16): e202200236. Selected as a VIP paper.

349   Danielsson, A., M.M. Kogut, M. Maszota-Zieleniak, P. Chopra, G.J. Boons, and S.A. Samsonov. 2022. Molecular dynamics-based descriptors of 3-O-sulfated heparan sulfate as contributors of protein binding specificity. Comput. Biol. Chem. 99: 107716.

348   Madunic, K., O.A. Mayboroda, T. Zhang, J. Weber, G.J. Boons, H. Morreau, R. van Vlierberghe, T. van Wezel, G.S.M. Lageveen-Kammeijer, and M. Wuhrer. 2022. Specific (sialyl-)Lewis core 2 O-glycans differentiate colorectal cancer from healthy colon epithelium Theranostics 12(10): 4498-4512.

347   Latchoumane, C.F., P. Chopra, L. Sun, A. Ahmed, F. Palmieri, H.F. Wu, R. Guerreso, K. Thorne, N. Zeltner, G.J. Boons,* and L. Karumbaiah.* 2022. Synthetic heparan sulfate hydrogels regulate neurotrophic factor signaling and neuronal network activity. ACS Appl. Mater. Interfaces 14(25): 28476-28488.

346   Sheikh, M.O., C.J. Capicciotti, L. Liu, J. Praissman, D. Ding, D.G. Mead, M.A. Brindley, T. Willer, K.P. Campbell, K.W. Moremen, L. Wells, and G.J. Boons. 2022. Cell surface glycan engineering reveals that matriglycan alone can recapitulate dystroglycan binding and function. Nat. Commun. 13(1): 3617. Featured on Nat. Commun. Editors’ Highlights page “Structural biology, biochemistry and biophysics” by P. Lössl (Juli 12, 2022).

345   Li, Z., L. Liu, L. Unione, Y. Lang, R.J. de Groot, and G.J. Boons. 2022. Synthetic O-acetyl-N-glycolylneuraminic acid oligosaccharides reveal host-associated binding patterns of coronaviral glycoproteins. ACS Inf. Dis. 8(5): 1041-1050.

344   Laman, J.D., R. Huizinga, G.J. Boons, and B.C. Jacobs. 2022. Guillain-Barré syndrome: expanding the concept of molecular mimicry. Trends Immunol. 43(4): 296-308

343   Spruit, C.M., X. Zhu, I. Tomris, M. Rios Carrasco, A.X. Han, F. Broszeit, R. van der Woude, K.M. Bouwman, M.M.T. Luu, K. Matsuno, Y. Sakoda, C.A. Russell, I.A. Wilson, G.J. Boons, and R.P. de Vries. 2022. N-glycolylneuraminic acid binding of avian and equine H7 influenza A viruses. J. Vir. 96(5): e0212021.

342   Tomris, I., K.M. Bouwman, Y. Adolfs, D. Noack, R. van der Woude, G. Kerster, S. Herfst, R.W. Sanders, M.J. van Gils, G.J. Boons, B.L. Haagmans, R.J. Pasterkamp, B. Rockx, and R.P. de Vries. 2022. Distinct spatial arrangements of ACE2 and TMPRSS2 expression in Syrian hamster lung lobes dictates SARS-CoV-2 infection patterns. PLoS Pathog. 18(3): e1010340.

341   Luijkx, Y.M.C.A., A.J. Henselijn, G.P. Bosman, D.A.T. Cramer, C.A.P. Giesbers, E.M. van ‘t Veld, G.J. Boons, A.J.R. Heck, K.R. Reiding, K. Strijbis, and T. Wennekes. 2022. Detection of bacterial a-L-fucosidases with an ortho-quinone methide-based probe and mapping of the probe-protein adducts. Molecules 27(5): 1615.

340   Wu,J., P. Chopra, G.J. Boons, and J. Zaia. 2022. Influence of saccharide modifications on heparin lyase III substrate specificities. Glycobiology 32(3): 208-217.

339   Gaide, N., M.N. Lucas, M. Delpont, G. Croville, K.M. Bouwman, A. Papanikolaou, R. van der Woude, I.A. Gagarinov, G.J. Boons, R.P. de Vries, R. Volmer, A. Teillaud, T. Vergne, C. Bleuart, G, Le Loc'h, M, Delverdier, and J.L. Guérin. 2022. Pathobiology of highly pathogenic H5 avian influenza viruses in naturally infected Galliformes and Anseriformes in France during winter 2015-2016. Vet. Res. 53(1): 11.

338   Li, Z., L. Unione, L. Liu, Y. Lang, R.P. de Vries, R.J. de Groot, and G.J. Boons. 2022. Synthetic O-acetylated sialosides and their acetamido-deoxy analogs as probes for coronaviral hemagglutinin-esterase recognition. J. Am. Chem. Soc. 144(1): 424-435.

337   Nguyen, L., K.A. McCord, D.T. Bui, K.M. Bouwman, E.N. Kitova, M. Elaish, D. Kumawat, G.C. Daskhan, I. Tomris, L. Han, P. Chopra, T.-J. Yang, S.D. Willows, A.L. Mason, L.K. Mahal, T.L. Lowary, L.J. West, S.D. Hsu, T. Hobman, S.M. Tompkins, G.J. Boons, R.P. de Vries, M.S. Macauley, and J.S. Klassen. 2022. Sialic acid-dependent binding and viral entry of SARS-CoV-2. Nat. Chem. Biol. 18(1): 81-90.


336   Karlsson, R., P. Chopra, A. Joshi, Z. Yang, S.Y. Vakhrushev, T. Mandel Clausen, C.D. Painter, G.P. Szekeres, Y.-H. Chen, D.R. Sandoval, L. Hansen, J.D. Esko, K. Pagel, D.P. Dyer, J.E. Turnbull, H. Clausen,* G.J. Boons,* and R.L. Miller.* 2021. Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates. Sci. Adv. 7(52): eabl6026.

335   Meng, X., G.J. Boons, M.M.S.M. Wösten, and T. Wennekes. 2021. Metabolic labeling of legionaminic acid in flagellin glycosylation of Campylobacter jejuni identifies Maf4 as a putative legionaminyl transferase. Angew. Chem. Int. Ed. 60(47): 24811-24816.

334   Arunkumar, G.A., D. Bhavsar, T. Li, S. Strohmeier, V. Chromikova, F. Amanat, M. Bunyatov, P.C. Wilson, A.H. Ellebedy, G.J. Boons, V. Simon, R.P. de Vries, and F. Krammer. 2021. Functionality of the putative surface glycoproteins of the Wuhan spiny eel influenza virus. Nat. Commun. 12(1): 6161.

333   Schuurmans, C.C.L., A.J. Brouwer, J.A.W. Jong, G.J.P.H. Boons, W.E. Hennink, and T. Vermonden. 2021. Hydrolytic (in)stability of methacrylate esters in covalently cross-linked hydrogels based on chondroitin sulfate and hyaluronic acid methacrylate. ACS Omega 6(40): 26302-26310.

332   Broszeit, F., R.J. van Beek, L. Unione, T.M. Bestebroer, D. Chapla, J.-Y. Yang, K.W. Moremen, S. Herfst, R.A.M. Fouchier, R.P. de Vries, and G.J. Boons. 2021. Glycan remodeled erythrocytes facilitate antigenic characterization of recent A/H3N2 influenza viruses. Nat. Commun. 12(1): 5449.

331   Huang, J., P. Chopra, L. Liu, T. Nagy, J. Murray, R.A. Tripp, G.J. Boons, and J.J. Mousa. 2021. Structure, immunogenicity, and conformation-dependent receptor binding of the post-fusion human metapneumovirus F protein. J. Virol. 95(18): e00593-21.

330   Srivastava, A.D., L. Unione, M. Bunyatov, I.A. Gagarinov, S. Delgado, N.G.A. Abrescia, A. Ardá, and G.J. Boons. 2021. Chemoenzymatic synthesis of complex N-glycans of the parasite S. mansoni to examine the importance of epitope presentation on DC-SIGN recognition. Angew. Chem. Int. Ed. 60(35): 19287-19296.

329   Moure, M.J., A. Gimeno, S. Delgado, T. Diercks, G.J. Boons, J. Jimenez-Barbero, and A. Arda. 2021. Selective 13C-labels on repeating glycan oligomers to reveal protein binding epitopes through NMR: polylactosamine binding to galectins. Angew. Chem. Int. Ed. 60(34): 18777-18782.

328   Liu, L., P. Chopra, X. Li, K.M. Bouwman, S.M Tompkins, M.A. Wolfert, R.P. de Vries, and G.J. Boons. 2021. Heparan sulfate proteoglycans as an initial attachment factor for SARS-CoV-2. ACS Cent. Sci. 7(6): 1009-1018.

327   Li, Z., Y. Lang, L. Liu, M.I. Bunyatov, A. Isaza Sarmiento, R.J. de Groot, and G.J. Boons. 2021. Synthetic O-acetylated sialosides facilitate functional receptor identification for human respiratory viruses. Nat. Chem. 13(5): 496-503.

326   Spruit, C.M., N. Nemanichvili, M. Okamatsu, H. Takematsu, H., G.J. Boons, and R.P. de Vries. 2021. N-glycolylneuraminic acid in animal models for human influenza A virus. Viruses 13(5): 815.

325   Bouwman, K.M., I. Tomris, H.L. Turner, R. van der Woude, G.P. Bosman, B. Rockx, S. Herfst, B.L. Haagmans, A.B. Ward, G.J. Boons, and R.P. de Vries. 2021. Multimerization- and glycosylation-dependent receptor binding of SARS CoV-2 spike proteins. PLoS Pathog. 17(2): e1009282.

324   Sastre Toraño, J., O. Aizpurua-Olaizola, N. Wei, T. Li, L. Unione, G. Jiménez-Osés, F. Corzana, V.J. Somovilla, J.M. Falcon-Perez, and G.J. Boons. 2021. Identification of isomeric N-glycans by conformer distribution fingerprinting using ion mobility-mass spectrometry. Chem. Eur. J. 26(6): 2149-2154.

323   Chopra, P., A. Joshi, J. Wu, W. Lu, T. Yadavalli, M.A. Wolfert, D. Shukla, J. Zaia, and G.J. Boons. 2021. The 3-O-sulfation of heparan sulfate modulates protein binding and lyase degradation. Proc. Natl. Acad. Sci. U. S. A. 118(3): e2012935118.


322   Overeem, N.J., P.H.E. Hamming, O.C. Grant, D. Di Iorio, M. Tieke, M.C. Bertolino, Z. Li, G. Vos, R.P. de Vries, R.J. Woods,* N.B. Tito, G.J.P.H. Boons,* E. van der Vries,* and J. Huskens.* 2020. Hierarchical multivalent effects control influenza host specificity. ACS Cent. Sci. 6(12): 2311-2318.

321   Sun, L., P. Chopra, and G.J. Boons. 2020. Modular synthesis of heparan sulfate oligosaccharides having N-acetyl and N-sulfate moieties. J. Org. Chem. 85(24): 16082-16098.

320   Boruah, B.M., R. Kadirvelraj, L. Liu, A. Ramiah, C. Li, G. Zong, G.P. Bosman, J.-Y. Yang, L.-X. Wang, G.J. Boons, Z.A. Wood, and K.W. Moremen. 2020. Characterizing human a-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases. J. Biol. Chem. 295(50): 17027-17045.

319   Verpalen, E.C.J.M., A.J. Brouwer, and G.J. Boons. 2020. Synthesis of monophosphoryl lipid A using 2-naphtylmethyl ethers as permanent protecting groups. Carbohydr. Res. 498: 108152.

318   Srivastava, A.D., L. Unione, M.A. Wolfert, P. Valverde, A. Ardá, J. Jiménez-Barbero, and G.J. Boons. 2020. Mono- and di-fucosylated glycans of the parasitic worm S. mansoni are recognized differently by the innate immune receptor DC-SIGN. Chem. Eur. J. 26(67): 15605-15612. Selected as "Hot Paper"

317   Li, T., M.A. Wolfert, N. Wei, R. Huizinga, B.C. Jacobs, and G.J. Boons. 2020. Chemoenzymatic synthesis of Campylobacter jejuni lipo-oligosaccharide core domains to examine Guillain-Barré syndrome serum antibody specificities. J. Am. Chem. Soc. 142(46): 19611-19621.

316   Williams, C.R., L. Chen, E.S. Sheppard, P. Chopra, J. Locklin, G.J. Boons, and D.C. Krause. 2020. Distinct Mycoplasma pneumoniae interactions with sulfated and sialylated receptors. Infect. Immun. 88(11): e00392-20.

315   Lang, Y., W. Li, Z. Li, D. Koerhuis, A.C.S. van den Burg, E. Rozemuller, B.-J. Bosch, F.J.M. van Kuppeveld, G.J.P.H. Boons, E.G. Huizinga, H.M. van der Schaar, and R.J. de Groot. 2020. Coronavirus hemagglutinin-esterase and spike proteins co-evolve for functional balance and optimal virion avidity. Proc. Natl. Acad. Sci. U. S. A. 117(41): 25759-25770.

314   Trabszo,C. B. Ramms, P. Chopra, R. Lüllmann-Rauch, S. Stroobants, J. Sproß, A. Jeschke, T. Schinke, G.J. Boons, J.D. Esko, T. Lübke, and T. Dierks. 2020. Arylsulfatase K inactivation causes mucopolysaccharidosis due to deficient glucuronate desulfation of heparan and chondroitin sulfate. Biochem. J. 477(17): 3433-3451.

313   Du, W. M.A. Wolfert, B. Peeters, F.J.M. van Kuppeveld, G.J. Boons, E. de Vries, and C.A.M. de Haan. 2020. Mutation of the second sialic acid-binding site of influenza A virus neuraminidase drives compensatory mutations in hemagglutinin. PloS Pathog. 16(8): e1008816.

312   Lettow, M., M. Grabarics, K. Greis, E. Mucha, D. Thomas, P. Chopra, G.J. Boons, R. Karlsson, J. Turnbull, G. Meijer, R. Miller, G. von Helden, and K. Pagel. 2020. Cryogenic infrared spectroscopy reveals structural modularity in the vibrational fingerprints of heparan sulfate diastereomers. Anal. Chem. 92(15): 10228-10232.

311   Jansen, A.J.G., T. Spaan, H.Z. Low, D. Di Iorio, J. van den Brand, M. Tieke, A. Barendrecht, K. Rohn, G. van Amerongen, K. Stittelaar, W. Baumgärtner, A. Osterhaus, T. Kuiken, G.J. Boons, J. Huskens, M. Boes, C. Maas, and E. van der Vries. 2020. Influenza-induced thrombocytopenia is dependent on the subtype and sialoglycan receptor and increases with virus pathogenicity. Blood Adv. 4(13): 2967-2978.

310   Shrestha, S., S. Katiyar, C.E. Sanz-Rodriguez, N.R. Kemppinen, H.W. Kim, R. Kadirvelraj, C. Panagos, N. Keyhaninejad, M. Colonna, P. Chopra, D.P. Byrne, G.J. Boons, E.V. Knaap, P.A. Eyers, A.S. Edison, Z.A. Wood, and N. Kannan. 2020. A novel redox-active switch in fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily. Sc. Signaling. 13(639): eaax6313.

309   Eggink D., M. Spronken, R. van der Woude, J. Buzink, F. Broszeit, R. McBride R, H.A. Pawestri, V. Setiawaty, J.C. Paulson, G.J. Boons, R.A.M. Fouchier, C.A. Russell, M.D. de Jong, and R.P. de Vries. 2020. Phenotypic effects of substitutions within the receptor binding site of highly pathogenic avian influenza H5N1 virus observed during human infection. J. Virol. 94(13): e00195-20.

308   Talsma, D.T., F. Poppelaars, W.A Dam, A.H Meter-Arkema, R.R Vives, P. Gál, G.J.P.H. Boons, P. Chopra, A. Naggi, M. Seelen, S. Philip Berger, M. Daha, C.A. Stegeman, and J. van den Born. 2020. MASP-2 is a heparin-binding protease; Identification of blocking oligosaccharides. Front. Immunol. 11: 732.

307   Dumas, E.K., H. Demiraslan, R.J. Ingram, R.M. Sparks, E. Muns, A. Zamora, J. Larabee, L. Garman, J. Ballard, G.J. Boons, J.A. James, Ü. Kayabas, M. Doganay, and A.D. Farris. 2020. Toxin-neutralizing antibodies elicited by naturally acquired cutaneous anthrax are elevated following severe disease and appear to target conformational epitopes. PLoS ONE 15(4): e0230782.

306   Miller, R.L., S.E. Guimond, R. Schwörer, O.V. Zubkova, P.C. Tyler, Y. Xu, J. Liu, P. Chopra, G.J. Boons, M. Grabarics, C. Manz, J. Hofmann, N. Karlsson, J.E. Turnbull, W.B. Struwe, and K. Pagel. 2020. Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides. Nat. Commun. 11(1): 1481.

305   Singh, J., C. Her, N. Supekar, G.J. Boons, V.V. Krishnan, and C.L. Brooks. 2020. Role of glycosylation on the ensemble of conformations in the MUC1 immunodominant epitope. J. Pept. Sc. 26(1): e3229.


304   Sastre Toraño, J., I.A. Gagarinov, G.M. Vos, F. Broszeit, A.D. Srivastava, M. Palmer, J.I. Langridge, O. Aizpurua-Olaizola, V.J. Somovilla, and G.J. Boons. 2019. Ion-mobility spectrometry can assign exact fucosyl positions in glycans and prevent misinterpretation of mass spectrometry data after gas-phase rearrangement. Angew. Chem. Int. Ed. 58(49): 17616-17620.

303   Hoeksma, J., T. Misset, C. Wever, J. Kemmink, J. Kruijtzer, K. Versluis, r.M.J. Liskamp, G.J. Boons, A.J.R. Heck, T. Boekhout, and J. den Hertog. 2019. A new perspective on fungal metabolites: identification of bioactive compounds from fungi using zebrafish embryogenesis as read-out. Sc. Rep. 9(1): 17546.

302   Liu, H., A. Joshi, P. Chopra, L. Liu, G.J. Boons, and J.S. Sharp. 2019. Salt-free fractionation of complex isomeric mixtures of glycosaminoglycan oligosaccharides compatible with ESI-MS and microarray analysis. Sc. Rep. 9(1): 16566.

301   Chopra, P., M.T. Logun, E.M. White, W. Lu, J. Locklin, L. Karumbaiah, and G.J. Boons. 2019. Fully synthetic heparan sulfate-based neural tissue construct that maintains the undifferentiated state of neural stem cells. ACS Chem. Biol. 14(9): 1921-1929.

300   Gray, C.J., L.G, Migas, P.E. Barran, K. Pagel, P.H. Seeberger, C.E. Eyers, G.J. Boons, N.L.B. Pohl, I. Compagnon, G. Widmalm, and S.L. Flitsch. 2019. Advancing solutions to the carbohydrate sequencing challenges. J. Am. Chem. Soc. 141(37): 14463-14479.

299   Wu, J., J. Wei, P. Chopra, G.J. Boons, C. Lin, and J. Zaia. 2019. Sequencing heparan sulfate using HILIC LC-NETD-MS/MS. Anal. Chem. 91(18): 11738-11746.

298   t' Hart, I.M.E.,T. Li, M.A. Wolfert, S. Wang, K.W. Moremen, and G.J. Boons. 2019. Chemoenzymatic synthesis of the oligosaccharide moiety of the tumor-associated antigen disialosyl globopentaosylceramide. Org. Biomol. Chem. 17(31): 7304-7308.

297   Gagarinov, I.A., T. Li, N. Wei, J. Sastre Toraño, R.P. de Vries, M.A. Wolfert, and G.J. Boons. 2019. Protecting group-controlled enzymatic glycosylation of oligo-N-acetyllactosamine derivatives. Angew. Chem. Int. Ed. 58(31): 10547-10552.

296   Lu, W., W. Du, V.J. Somovilla, G. Yu, D. Haksar, E.J. de Vries,  G.J. Boons, R.P. de Vries, C.A.M. de Haan, and R.J. Pieters. 2019. Enhanced inhibition of influenza A virus adhesion by di- and trivalent hemagglutinin inhibitors. J. Med. Chem. 62(13): 6398-6404.

295   Broszeit, F., N. Tzarum, X. Zhu, N. Nemanachvilli, D. Eggink, T. Leenders, Z. Li, L. Liu, M.A. Wolfert, A. Papanikolaou, C. Martinez-Romero, I.A. Gagarinov, W. Yu, A. Garcia-Sastre, T. Wennekes, M. Okamatsu, M.H. Verheije, I.A. Wilson, G.J. Boons, and R.P. de Vries. 2019. N-glycolylneuraminic acid as a receptor for influenza A viruses. Cell Rep. 27(11): 3284-3294.e6.

294   Du, W., H. Guo, V.S. Nijman, J. Doedt, E. van der Vries, J. van der Lee, Z. Li, G.J. Boons, F.J.M. van Kuppeveld, E. de Vries, M. Matrosovich, and C.A.M. de Haan. 2019. The 2nd sialic acid-binding site of influenza A virus neuraminidase is an important determinant of the hemagglutinin-neuraminidase-receptor balance. PLoS Pathog. 15(6):e1007860.

293   Tortorici, A. M., A.C. Walls, Y. Lang, C. Wang, Z. Li, D. Koerhuis, G.J. Boons, B.J. Bosch, F.A. Rey, R.J. de Groot, and D. Veesler. 2019. Structural basis for human coronavirus attachment to sialic acid receptors. Nat. Struct. Mol. Biol. 26(6): 481-489.

292   Bouwman, K.M., M. Delpont, F. Broszeit, R. Berger, E.A.W.S. Weerts, M.-N. Lucas, M. Delverdier, S. Belkasmi, A. Papanikolaou, G.J. Boons, J.-L. Guérin, R.P. de Vries, M.F. Ducatez, and M.H. Verheij. 2019. Guinea fowl coronavirus diversity has phenotypic consequences for glycan and tissue binding. J. Virol. 93(10): e00067-19.

291   Hu, Y., X. Cao, X. Li, Y. Wang, G.J. Boons, J. Deng, and H. Jiang. 2019.The three-dimensional structure and recognition mechanism of Manduca sexta peptidoglycan recognition protein-1. Insect Biochem. Mol. Biol. 108: 44-52.

290   van der Beek, S.L., A. Zorzoli, E. Çanak, R.N. Chapman, B.H. Meyer, D. Evangelopoulos, L.P.S. de Carvalho, G.J. Boons, H.C. Dorfmueller, and N.M. van Sorge. 2019. Streptococcal dTDP-L-rhamnose biosynthesis enzymes: functional characterization and lead compound identification. Mol. Microbiol. 111(4): 951-964.

289   Li, T., L. Liu, N. Wei, J.-Y. Yang, D.G. Chapla, K.W. Moremen, and G.J. Boons. 2019. An automated platform for the enzyme-mediated assembly of complex oligosaccharides. Nat. Chem. 11(3): 229-236. Highlighted in Nat. Chem. News & Views: Pohl, N.L.B. 2019. Robots command enzymes. Nat. Chem. 11(3): 201-203.

288   Nemanachvili, N.,I. Tomris, H.L. Turner, R. McBride, O.C. Grant, R. van der Woude, M.H. Aldosari, R.J. Pieters, R.J. Woods, J.C. Paulson, G.J. Boons, A.B. Ward, M.H. Verheije, and R.P. de Vries. 2019. Fluorescent trimeric hemagglutinins reveal multivalent receptor-binding properties. J. Mol. Biol. 431(4): 842-856.

287   Hulswit, R.J.G., Y. Lang, M.J.G. Bakkers, W. Li, Z. Li, A. Schouten, B. Ophorst, F.J.M. van Kuppeveld, G.J. Boons, B.J. Bosch, E.G. Huizinga, and R.J. de Groot. 2019. Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor binding site in spike protein domain A. Proc. Natl. Acad. Sci. U. S. A. 16(7): 2681-2690.

286   Liu, L., A.R. Prudden, C.J. Capicciotti, G.P. Bosman, J.-Y. Yang, D.G. Chapla, K.W. Moremen, and G.J. Boons. 2019. Streamlining the chemoenzymatic synthesis of complex N-glycans by a stop and go strategy. Nat. Chem. 11(2): 161-169.

285   Marcelo, F., N. Supekar, F. Corzana, J.C. van der Horst, I.M. Vuist, D.H Live, G.J. Boons, D.F. Smith, and S.J. van Vliet. 2019. Identification of a secondary binding site in human macrophage galactose-type lectin by microarray studies: Implications for the molecular recognition of its ligands. J. Biol. Chem. 294(4): 1300-1311.


284  Chapman, R.N., L. Liu, and G.J. Boons. 2018. 4,6-O-Pyruvyl ketal modified N-acetylmannosamine of the secondary cell wall polysaccharide of Bacillus anthracis is the anchoring residue for its surface layer proteins. J. Am. Chem. Soc. 140(49): 17079–17085.

283  Du, W., M. Dai, Z. Li, G.J. Boons, B. Peeters, F.J.M. van Kuppeveld, E. de Vries, and C.A.M. de Haan. 2018. Substrate binding by the second sialic acid-binding site of influenza A virus N1 neuraminidase contributes to enzymatic activity. J. Virol. 92(20): e01243-18.

282  Moure, M.J., A. Eletsky, Q. Gao, L.C. Morris, J.-Y. Yang, D. Chapla, Y. Zhao, C. Zong, I.J. Amster, K.W. Moremen, G.J. Boons, and J.H. Prestegard. 2018. Paramagnetic tag for glycosylation sites in glycoproteins: Structural constraints on heparan sulfate binding to Robo1. ACS Chem. Biol. 13(9): 2560-2567.

281  Yu, S.-H., P. Zhao, P.K. Prabhakar, T. Sun, A. Beedle, G.J. Boons, K.W. Moremen, L. Wells, and R. Steet. 2018. Defective mucin-type glycosylation on a-dystroglycan in COG-deficient cells increases its susceptibility to bacterial proteases. J. Biol. Chem. 293(37): 14534-14544.

280  Yi, F., X. Hong, A.B. Kumar, C. Zong, G.J. Boons, C.R. Scott, F. Turecek, B.H. Robinson, and M.H. Gelb. 2018. Detection of mucopolysaccharidosis III-A (Sanfilippo Syndrome-A) in dried blood spots (DBS) by tandem mass spectrometry. Mol. Genet. Metab. 125(1-2): 59-63.

279  Liang Q., P. Chopra, G.J. Boons, and J.S. Sharp. 2018. Improved de novo sequencing of heparin/heparan sulfate oligosaccharides by propionylation of sites of sulfation. Carbohydr. Res. 465: 16-21.

278  Hogan, J.D., J.A. Klein, J. Wu, P. Chopra, G.J. Boons, L. Carvalho, C. Lin, and J. Zaia. 2018. Software for peak finding and elemental composition assignment for glycosaminoglycan tandem mass spectra. Mol. Cell. Proteomics 17(7): 1448-1456.

277  Chinoy, Z.S., F. Friscourt, C. Capicciotti, P. Chiu, and G.J. Boons. 2018. Chemoenzymatic synthesis of asymmetrical multi-antennary N-glycans to dissect glycan-mediated interactions between human sperm and oocytes. Chem. Eur. J. 24(31): 7970-7975. Selected as a VIP paper.

276  Wu, J., J. Wei, J.D. Hogan, P. Chopra, A. Joshi, W. Lu, J.A. Klein, G.J. Boons, C. Lin, and J. Zaia. 2018. Negative electron transfer dissociation sequencing of 3-O-sulfation-containing heparan sulfate oligosaccharides. J. Am. Soc. Mass Spectrom. 29(6): 1262-1272.

275  Zhao Y., J.Y. Yang, D.F. Thieker, Y. Xu, C. Zong, G.J. Boons, J. Liu, R.J. Woods, K.W. Moremen, I.J. Amster. 2018. A traveling wave ion mobility spectrometry (TWIMS) study of the Robo1-heparan sulfate interaction. J. Am. Soc. Mass Spectrom. 29(6): 1153-1165.

274  Lu, W., C. Zong, P. Chopra, L. Pepi, Y. Xu, I.J. Amster, J. Liu,and G.J. Boons. 2018. Controlled chemoenzymatic synthesis of heparan sulfate oligosaccharides. Angew. Chem. Int. Ed. 57(19): 5340-5344.

273  Kadirvelraj, R., J.-Y. Yang, J.H. Sanders, L. Liu, A. Ramiah, P.K. Prabhakar, G.J. Boons, Z.A. Wood, and K.W. Moremen. 2018. Human N-acetylglucosaminyltransferase II substrate recognition uses a modular architecture that includes a convergent exosite. Proc. Natl. Acad. Sci. U. S. A. 115(18): 4637-4642.

272  Sychantha, D., R. Chapman, N.C. Bamford, G.J. Boons, P.L. Howell, and A.J. Clarke. 2018. Molecular basis for the attachment of S-layer proteins to the cell wall of Bacillus anthracis. Biochemistry 57(13): 1949-1953.

271  Williams C., F. Royo, O. Aizpurua-Olaizola, R. Pazos, G.J. Boons, N.-C. Reichardt, and J.M. Falcon-Perez. 2018. Glycosylation of extracellular vesicles: current knowledge, tools and clinical perspectives. J. Extracell. Vesicles. 7(1): 1442985.

270  Aizpurua-Olaizola O., J. Sastre Toraño, J.M. Falcon-Perez, C. Williams, N. Reichardt, and G.J. Boons. 2018. Mass spectrometry for glycan biomarker discovery. Trends Anal. Chem. 100: 7-14.

269  Aizpurua-Olaizola O., J. Sastre Toraño, A.V. Pukin, O. Fu, G.J. Boons, G.J. de Jong, and R.J. Pieters. 2018. Affinity capillary electrophoresis for the assessment of binding affinity of carbohydrate-based cholera toxin inhibitors. Electrophoresis 39(2): 344-347.

268  Supekar, N.T., V. Lakshminarayanan, C. Capicciotti, A. Sirohiwal, C.S. Madsen, M.A. Wolfert, P.A. Cohen, S.J. Gendler, and G.J. Boons. 2018. Synthesis and immunological evaluation of a multicomponent cancer vaccine candidate containing a long MUC1 glycopeptide. ChemBioChem 19(2): 121-125.

267  Sychantha, D., D.J. Little, R.N. Chapman, G.J. Boons, H. Robinson, P.L. Howell, and A.J. Clarke. 2018. PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides. Nat. Chem. Biol. 14(1): 79-85.


266  Moure, M.J., Y. Zhuo, G. J. Boons,* and J. H. Prestegard.* 2017. Perdeuterated and 13C-enriched myo-inositol for DNP assisted monitoring of enzymatic phosphorylation by inositol-3-kinase. Chem. Commun. 53(92): 12398-12401.

265  Liu, L., A.R. Prudden, G.P. Bosman, and G.J. Boons. 2017. Improved isolation and characterization procedure of sialylglycopeptide from egg yolk powder. Carbohydr. Res. 452: 122-128.

264  Klamer, Z., B. Staal, A.R. Prudden, L. Liu, D.F. Smith, G.J. Boons, and B. Haab. 2017. Mining high-complexity motifs in glycans: a new language to uncover the fine-specificities of lectins and glycosidases. Anal. Chem. 89(22): 12342-12350.

263  Benedetti, E., M. Pucic-Bakovic, T. Keser, A. Wahl, A. Hassinen, J.Y. Yang, L. Lui, I. Trbojevic Akmacic, G. Razdorov, J. Štambuk, L. Klaric, I. Ugrina, M.H.J. Selman, M. Wuhrer, I. Rudan, O. Polasek, C. Hayward, H. Grallert, K. Strauch, A. Peters, T. Meitinger, C. Gieger, M. Vilaj, , G.J. Boons, K.W. Moremen, T. Ovchinnikova, N. Bovin, S. Kellokumpu, F.J. Theis, G. Lauc, and J. Krumsiek. 2017. Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway. Nat. Commun. 8: 1483. (Erratum author affiliation in: Nat. Commun. 2018 9(1): 706).

262  Capicciotti, C.J., C. Zong, M.O. Sheikh, T. Sun, L. Wells, and G.J. Boons. 2017. Cell-surface glyco-engineering by exogenous enzymatic transfer using a bifunctional CMP-Neu5Ac derivative. J. Am. Chem. Soc. 139(38): 13342-13348. Highlighted in ACS Chem. Biol.: Underwood, J.G. 2017. Synthetic décor on the extracellular canvas. ACS Chem. Biol. 12: 2480-2481.

261  Agyekum, I., C. Zong, G.J. Boons, J, and I.J. Amster. 2017. Single stage tandem mass spectrometry assignment of the C-5 uronic acid stereochemistry in heparan sulfate tetrasaccharides using electron detachment dissociation. J. Am. Soc. Mass Spectrom. 28(9): 1741-1750.

260  Ding, N., X. Li, Z.S. Chinoy, and G.J. Boons. 2017. Synthesis of a glycosylphosphatidylinositol anchor derived from Leishmania donovanithat can be functionalization by Cu-catalyzed azide-alkyne cycloadditions. Org. Lett. 19(14): 3827-3830.

259  Zong, C.,A. Venot,X. Li,W. Lu,W. Xiao,J.L. Wilkes,C.L. Salanga, T.M. Handel,L. Wang,M.A. Wolfert,and G.J. Boons. 2017. Heparan sulfate microarray reveals that heparan sulfate-protein binding exhibits different ligand requirements J. Am. Chem. Soc. 139(28): 9534-9543.

258  Lin, A.E., C.A. Autran, A. Szyszka, T. Escajadillo, M. Huang, K. Godula, A.R. Prudden, G.J. Boons, A.L. Lewis, K.S. Doran, V. Nizet, and L. Bode. 2017. Human milk oligosaccharides inhibit growth of group B Streptococcus. J. Biol. Chem. 292(27): 11243-11249.

257  Prudden, A.R., L. Liu, C.J. Capicciotti, M.A. Wolfert, S. Wang, Z. Gao, L. Meng, K.W. Moremen, and G.J. Boons. 2017. Synthesis of asymmetrical multiantennary human milk oligosaccharides. Proc. Natl. Acad. Sci. U. S. A. 114(27): 6954-6959.

256  Movahedin, M., T.M. Brooks, N.T. Supekar, N. Gokanapudi, G.J. Boons, and C.L. Brooks. 2017. Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen. Glycobiology 27(7): 677-687.

255  Dhamale, O.,R.E. Lawrence, E.M. Wiegmann, B.A. Shah, K. al-Mafraji, W.C. Lamanna, T. Lübke, T. Dierks, G.J. Boons, and J.D. Esko. 2017. Arylsulfatase K is the lysosomal 2-sulfogluronate sulfatase. ACS Chem. Biol. 12(2): 367-373.

254  Halmo, S.M., D. Singh, S. Patel, S. Wang, M. Edlin, G.J. Boons, K.W. Moremen, D. Live, and L. Wells. 2017. Protein O-linked mannose ß-1,4-N-acetylglucosaminyltransferase 2 (POMGNT2) is a gatekeeper enzyme for functional glycosylation of a-dystroglycan. J. Biol. Chem. 292(6): 2101-2109.

253  Gagarinov, I.A., T. Li, J. Sastre Toraño, T. Caval, A.D. Srivastava, J.A.W. Kruijtzer, A.J.R. Heck, and G.J. Boons. 2017. Chemoenzymatic approach for the preparation of asymmetric bi-, tri- and tetra-antennary N-glycans from a common precursor. J. Am. Chem. Soc. 139(2): 1011–1018.

252  Zhao, Y., A. Singh, Y. Xu, C. Zong, F. Zhang, G.J. Boons, J. Liu, R.J. Linhardt, R.J. Woods, and I.J. Amster. 2017. Gas-phase analysis of the complex of fibroblast growth factor 1 with heparan sulfate: a traveling wave ion mobility spectrometry (TWIMS) and molecular modeling study. J. Am. Soc. Mass Spectrom. 28(1): 96-109.


251  Li, T., M. Huang, L. Liu, S. Wang, K.W. Moremen, and G.J. Boons. 2016. Divergent chemoenzymatic synthesis of asymmetrical core fucosylated and core-unmodified N-glycans. Chem. Eur. J. 22(52): 18742-18746.

250  Gao, Q., C.-Y. Chen, C. Zong, S. Wang, A. Ramiah, P. Prabhakar, L. Morris, G.J. Boons, K. Moremen, and J. Prestegard. 2016. Structural aspects of heparan sulfate binding to Robo1-Ig1-2. ACS Chem. Biol. 11(11): 3106-3113.

249  Singh, A., M.B. Tessier, K. Pederson, X. Wang, A.P. Venot, G.J. Boons, J.H. Prestegard, and R.J Woods. 2016. Extension and validation of the GLYCAM force field parameters for modeling glycosaminoglycans. Can. J. Chem. 94(11): 927-935.

248  Zong, C., R. Huang, E. Condac, Y. Chiu, W. Xiao, X. Li, W. Lu, M. Ishahara, S. Wang, A. Ramiah, M. Stickney, P. Azadi, I.J. Amster, K.W. Moremen, L. Wang, J.S. Sharp, and G.J. Boons. 2016. Integrated approach to identify heparan sulfate ligand requirements of Robo1. J. Am. Chem. Soc. 138(39): 13059-13067.

247  Bode, L., N. Contractor, D. Barile, N. Pohl, A. Prudden, G.J. Boons, Y.-S. Jin, and S. Jennewein. 2016. Overcoming the limited availability of human milk oligosaccharides: challenges and opportunities for research and application. Nutr. Rev. 74(10): 635-644.

246  Sun, T.,S.-H. Yu,P. Zhao, L. Meng, K.W. Moremen, L. Wells, R. Steet, and G.J. Boons.. 2016. One-step selective exoenzymatic labeling (SEEL) strategy for the biotinylation and identification of glycoproteins of living cells. J. Am. Chem. Soc. 138(36): 11575-11582.

245  Li, X., S.J.H. Martin, Z.S. Chinoy, L. Liu, B. Rittgers, R.A. Dluhy, and G.J. Boons. 2016. Label-free detection of glycan-protein interactions for array development by Surface Enhanced Raman Spectroscopy (SERS). Chem. Eur. J. 22(32): 11180-11185.

244  Bakkers, M.J.G., Q. Zeng, L.J. Feitsma, R.J.G. Hulswit, Z. Li, A. Westerbeke, F.J.M. van Kuppeveld, G.J. Boons, M.A. Langereis, E.G. Huizinga, and R.J. de Groot. 2016. Coronavirus receptor switch explained from the stereochemistry of protein-carbohydrate interactions and a single mutation. Proc. Natl. Acad. Sci. U. S. A. 113(22): E3111-E3119.

243  Huang, R., C. Zong, A. Venot, Y. Chiu, D. Zhou, G.J. Boons, and J.S. Sharp. 2016. De novo sequencing of complex mixtures of heparan sulfate oligosaccharides. Anal. Chem. 88(10): 5299-5307.

242  Wang, K., F. Friscourt, C. Dai, L. Wang, Y. Zheng, G.J. Boons, S. Wang, and B. Wang. 2016. A metal-free turn-on fluorescent probe for the fast and sensitive detection of inorganic azides. Bioorg. Med. Chem. Lett. 26(7): 1651-1654. Coverage in Synform: Synform 2016/09: A131–A134.

241  Fang, T.,  Y. Gu,W. Huang, and G.J. Boons. 2016. Mechanism of glycosylation of anomeric sulfonium ions. J. Am. Chem. Soc. 138(9): 3002-3011.

240  Ríos, P., T.S. Carter, T.J. Mooibroek, M.P. Crump, M. Lisbjerg, M. Pittelkow, N.T. Supekar, G.J. Boons, and A.P. Davis. 2016. Synthetic receptors for high-affinity recognition of O-GlcNAc derivatives. Angew. Chem. Int. Ed. 55(10): 3387-3392.

239  Martínez-Sáez, N., N.T. Supekar, M.A. Wolfert, I.A. Bermejo, R. Hurtado-Guerrero, J.L. Asensio, J. Jiménez-Barbero, J.H. Busto, A. Avenoza, G.J. Boons, J.M. Peregrina, and F. Corzana. 2016.Mucin architecture behind the immune response: design and evaluation and conformational analysis of an antitumor vaccine derived from an unnatural MUC1 fragment. Chem. Sc. 7(3): 2294-2301.

238  Yu, S.-H., P. Zhao, T. Sun, Z. Gao, K.W. Moremen, G.J. Boons, L. Wells, and R. Steet. 2016. Selective exo-enzymatic labeling detects increased cell surface sialoglycoprotein expression upon megakaryocytic differentiation. J. Biol. Chem. 291(8): 3982-3989.

237  Hudlikar, M.S., X. Li, I.A. Gagarinov, N. Kolishetti, M.A. Wolfert, and G.J. Boons. 2016. Controlled multi-functionalization facilitates targeted delivery of nanoparticles to cancer cells. Chem. Eur. J. 22(4): 1415-1423.

236  Lakshminarayanan V., N.T. Supekar, J. Wei, D.B. McCurry, A.C. Dueck, H.E. Kosiorek, P.P. Trivedi, J.M. Bradley, C.S. Madsen, L.B. Pathangey, D. Hoelzinger, M.A. Wolfert, G.J. Boons, P.A. Cohen, and S.J. Gendler. 2016. MUC1 vaccines, comprised of glycosylated or non-glycosylated peptides or tumor-derived MUC1, can circumvent immunoediting to control tumor growth in MUC1 transgenic mice. PLoS ONE 11(1): e0145920.


235  van der Beek, S.L., Y. Le Breton, A.T. Ferenbach, R.N. Chapman, D.M.F. van Aalten, I. Navratilova, G.J. Boons, K.S. McIver, N.M. van Sorge, and H.C. Dorfmueller. 2015. GacA is essential for Group A Streptococcus and defines a new class of monomeric dTDP-4-dehydrorhamnose reductases (RmlD). Mol. Microbiol. 98(5): 946-962.

234  Agyekum, I., A.B. Patel, C.L. Zong, G.J. Boons, and I.J. Amster. 2015. Assignment of hexuronic acid stereochemistry in synthetic heparan sulfate tetrasaccharides with 2-O-sulfo uronic acids using electron detachment dissociation. Int. J. Mass Spectrom.390: 163-169.

233  Friscourt, F., C.J. Fahrni, and G.J. Boons. 2015. Fluorogenic strain-promoted alkyne-diazo cycloadditions. Chem. Eur. J. 21(40): 13996-14001.

232  Huang, W., Q. Gao, and G.J. Boons. 2015. Assembly of a complex branched oligosaccharide by combining fluorous-supported synthesis and stereoselective glycosylations using anomeric sulfonium ions. Chem. Eur. J. 21(37): 12920-12926. Selected for frontispiece.

231  Liu, L., J. Zha, A. DiGiandomenico, D. McAllister, C.K. Stover, Q. Wang, and G.J. Boons. 2015. Synthetic enterobacterial common antigen (ECA) for the development of a universal immunotherapy for drug-resistant Enterobacteriaceae. Angew. Chem. Int. Ed. 54(37): 10953-10957. Press release by Angew. Chem. Int. Ed. News Room (Juli 31, 2015): Sugar Antigen Lost its Resistance. Successful chemical synthesis of enterobacterial common antigen relevant for immunotherapy. Highlighted in C&EN: Borman, S. A. 2015. Enterobacterial antigen analogs synthesized. Carbohydrate chemistry: Protein conjugates of the antigen could serve as vaccines for pathogenic bacteria. Chemical & Engineering News, 93(32): 50.

230  Chinoy, Z.S., C.M. Schafer, C.M. West, and G.J. Boons. 2015. Chemical synthesis of a glycopeptide derived from Skp1 for probing protein specific glycosylation. Chem. Eur. J. 21(33): 11779–11787.

229  Ledin, P.A., W. Xu, F. Friscourt, G.J. Boons, and V. Tsukruk. 2015. Branched polyhedral oligomeric silsesquioxane nanoparticles prepared via strain-promoted 1,3-dipolar cycloadditions. Langmuir 31(29): 8146–8155.

228  Thompson, P., V. Lakshminarayanan N.T. Supekar, J.M. Bradley, P.A. Cohen, M.A. Wolfert, S.J. Gendler, and G.J. Boons. 2015. Linear synthesis and immunological properties of a fully synthetic vaccine containing a sialylated MUC1 glycopeptide. Chem. Commun. 51(50): 10214-10217.

227  Gagarinov, I.A., T. Fang, L. Liu, A.D. Srivastava, and G.J. Boons. 2015. Synthesis of Staphylococcus aureus Type 5 trisaccharide repeating unit: solving the problem of lactamization. Org. Lett. 17(4): 928-931.

226  Forestier, C.L. Q. Gao, and G.J. Boons. 2015. Leishmania lipophosphoglycan: how to establish structure-activity relationships for this highly complex and multifunctional glycoconjugate? Front. Cell. Infect. Microbiol. 4 (Aricle 193): 1-7.

225  Huang, Y., Y. Mao, C. Zhong, C. Lin, G.J. Boons, and J. Zaia. 2015. Discovery of a heparan sulfate 3-O-sulfation specific peelingreaction. Anal. Chem. 87(1): 592-600.


224  Praissman, J.L., D.H. Live, S. Wang, A. Ramiah, Z.S. Chinoy, G.J. Boons, K.W. Moremen, and L. Wells. 2014. B4GAT1 is the priming enzyme for the LARGE-dependent functional glycosylation of alpha-dystroglycan. eLife 3: e03943.

223  Hu, H., Y. Huang, Y. Mao, X. Yu, Y. Xu, J. Liu, C. Zong, G.J. Boons, C. Lin, Y. Xia, and J. Zaia. 2014. A computational framework for heparan sulfate sequencing using high-resolution tandem mass spectra. Mol. Cell. Proteomics 13(9): 2490-2502.

222  Prudden, A.R., Z.S. Chinoy,M.A. Wolfert, and G.J. Boons. 2014. A multifunctional anomeric linker for the chemoenzymatic synthesis of complex oligosaccharides. Chem. Commun. 50(54): 7132-7135.

221  Li, X., T. Fang,and G.J. Boons. 2014. Preparation of well-defined antibody–drug conjugates through glycan remodeling and strain-promoted azide–alkyne cycloadditions. Angew. Chem. Int. Ed. 53(28): 7179-7182.

220  Abdel Aal, A.M., V. Lakshminarayanan, P. Thompson, N. Supekar, J.M. Bradley, M.A. Wolfert, P.A. Cohen, S.J. Gendler, and G.J. Boons. 2014. Immune and anticancer responses elicited by fully synthetic aberrantly glycosylated MUC1 tripartite vaccines modified by a TLR2 or TLR9 agonist. ChemBioChem 15(10): 1508-1513.

219  Ledin, P.A., N. Kolishetti, M.S. Hudlikar, and G.J. Boons. 2014. Exploring strain-promoted 1,3-dipolar cycloadditions on end functionalized polymers. Chem. Eur. J. 20(28): 8753-8760.

218  Arumugam, S., J. Guo, N.E. Mbua, F. Friscourt, N. Lin, E. Nekongo, G.J. Boons, and V.V. Popik. 2014. Selective and reversible photochemical derivatization of cysteine residues in peptides and proteins. Chem. Sci.5(4): 1591-1598.

217  Dhamale, O.P., C. Zhong, K. Al-Mafraji, and G.J. Boons. 2014. New glucuronic acid donors for the modular synthesis of heparan sulfate oligosaccharides. Org. Biomol. Chem. (12): 2087-2098.

216  Kailemia M.J., M. Park, D.A. Kaplan, A. Venot, G.J. Boons, L. Li, R.J Linhardt, and I.J. Amster. 2014. High-field asymmetric-waveform ion mobility spectrometry and electron detachment dissociation for isobaric mixtures of glycosaminoglycans. J. Am. Soc. Mass Spectrom. 25(2): 258-268.


215  Li, H., K. Mo, Q. Wang, C.K. Stover, A. DiGiandomenico, and G.J. Boons. 2013. Epitope mapping of monoclonal antibodies using synthetic oligosaccharidesuncovers novel aspects of immune recognition of the Psl exopolysaccharide of Pseudomonas aeruginosa. Chem. Eur. J. 19(51): 17425-17431.

214  Live, D., L. Wells, and G.J. Boons. 2013. Dissecting the molecular basis for the role of the O-mannosylation pathway in disease: a-dystroglycan and forms of muscular dystrophy. ChemBioChem 14(18): 2392-2402.

213  Mbua, N.E., X. Li,H. Flanagan-Steet, L. Meng, K. Aoki, K.W. Moremen, M.A. Wolfert, R. Steet, and G.J. Boons. 2013. Selective exo-enzymatic labeling of N-glycans of living cells by recombinant ST6Gal I. Angew. Chem. Int. Ed. 52(49): 13012-13015. Selected as "Hot Paper".

212  Wolfert, M.A. and G.J. Boons. 2013. Adaptive immune activation: glycosylation does matter. Nat. Chem. Biol. 9(12): 776-784.

211  Ledin, P.A., N. Kolishetti, and G.J. Boons. 2013. Multifunctionalization of polymers by strain-promoted cycloadditions. Macromolecules 46(19): 7759-7768.

210  Heimburg-Molinaro J., J.W. Priest, D. Live, G.J. Boons, X. Song, R.D. Cummings, and J.R. Mead. 2013. Microarray analysis of the human antibody response to synthetic Cryptosporidium glycopeptides. Int. J. Parasitol. 43(11): 901-907.

209  Kaeothip, S. and G.J. Boons. 2013. Chemical synthesis of b-arabinofuranosyl containing oligosaccharides derived from plant cell wall extensins. Org. Biomol. Chem. 11(31): 5136-5146.

208  Wang, Z.,Z. Chinoy,S. Ambre,W. Peng,R. McBride, R.P. de Vries,J. Glushka,J.C. Paulson, and G.J. Boons. 2013. A general strategy for the chemoenzymatic synthesis of asymmetrically branched N-glycans. Science 341(6144): 379-383. Highlighted in Science; C&EN; Nature News; Nature Methods: Kiessling, L. L. and M.B. Kraft. 2013. A path to complex carbohydrates. Science 341(6144): 357-358; Arnaud, C.H. 2013. Branching out in different ways.Carbohydrate chemistry: New synthetic strategy leads to asymmetrically branched N-glycans. Chem. Eng. News 91(30): 9; Johnston, R. 2013. Asymmetrical glycans synthesized in lab. Nature, doi:10.1038/nature. 2013.13454; Eisenstein, M. 2013. Constructing complicated carbohydrates. Nat. Methods 10(10): 932.

207  Arumugam, S., S.V. Orski, N.E. Mbua, C. McNitt, G.J. Boons, J. Locklin, and V.V. Popik. 2013. Photo-click chemistry strategies for spatiotemporal control of metal-free ligation, labeling, and surface derivatization. Pure Appl. Chem. 85(7): 1499-1513.

206  Mbua, N.E., H. Flanagan-Steet, S. Johnson, M.A. Wolfert, G.J. Boons, and R. Steet. 2013.  Abnormal accumulation of sialylated glycoproteins visualized in Niemann-Pick Type C cells using the chemical reporter strategy. Proc. Natl. Acad. Sci. U. S. A. 110(25): 10207-10212.

205  Zong, C., A. Venot, O. Dhamale, and G.J. Boons. 2013. Fluorous supported modular synthesis of heparin sulfate oligosaccharides. Org. Lett. 15(2): 342-345.

204  Talabnin, K., K. Aoki, P. Saichua, S. Wongkham, S. Kaewkes, G.J. Boons, B. Sripa, and M. Tiemeyer. 2013. Stage-specific expression and antigenicity of glycoprotein glycans isolated from the human liver fluke, Opisthorchis viverrini. Int. J. Parasitol. 43(1): 37-50.


203  Leach III, F.E., S. Arungundram, K. Al-Mafraji, A. Venot, G.J. Boons, and I.J. Amster. 2012. Electron detachment dissociation of synthetic heparan sulfate glycosaminoglycan tetrasaccharides varying in degree of sulfation and hexuronic acid stereochemistry. Int. J. Mass Spectrom. 330-332: 152-159.

202  Friscourt, F., C.J. Fahrni, and G.J. Boons. 2012. A fluorogenic probe for the catalyst-free detection of azide-tagged molecules. J. Am. Chem. Soc. 134(45): 18809-18815.

201  Mo, K.F., X. Li, H. Li, L.Y. Low, C.P. Quinn,and G.J. Boons. 2012. Endolysins of Bacillus anthracis bacteriophages recognize unique carbohydrate epitopes of vegetative cell wall polysaccharides with high affinity and selectivity. J. Am. Chem. Soc. 134(37): 15556–15562.

200  Boltje, T.J., W. Zhong, J. Park, M.A. Wolfert, W. Chen, and G.J. Boons. 2012. Chemical synthesis and immunological evaluation of the inner-core oligosaccharide of Francisella tularensis. J. Am. Chem. Soc. 134(34): 14255-14262.

199  Fang, T., K.F. Mo, and G.J. Boons. 2012. Stereoselective assembly of complex oligosaccharides using anomeric sulfonium ions as glycosyl donors. J. Am. Chem. Soc. 134(17): 7545-7552.

198  Guo, J., G. Chen, X. Ning, X. Li, J. Zhou, A. Jagielska, B. Xu, and G.J. Boons. 2012. A chemo-mechanical tweezer for single molecular characterization of soft materials. Chem. Eur. J. 18(15): 4568-4574.

197  Friscourt, F., P.A. Ledin,N.E. Mbua, H.R Flanagan-Steet, M.A. Wolfert,R. Steet,and G.J. Boons. 2012. Polar dibenzocyclooctynes for selective labeling of extracellular glycoconjugates of living cells. J. Am. Chem. Soc. 134(11): 5381-5389.

196  Lawrence, R., J.R. Brown, K. Al-Mafraji, W.C. Lamanna, J.R. Beitel, G.J. Boons, J.D. Esko, and B.E. Crawford. 2012. Disease-specific non-reducing end carbohydrate biomarkers for mucopolysaccharidoses. Nat. Chem. Biol. 8(2): 197-204.

195  Nguyen T.K., S. Arungundram, V.M. Tran, K. Raman, K. Al-Mafraji, A. Venot , G.J. Boons, and B. Kuberan. 2012. A synthetic heparan sulfate oligosaccharide library reveals the novel enzymatic action of D-glucosaminyl 3-O-sulfotransferase-3a. Mol. BioSyst. 8: 609-614.

194  van der Linden, W.A., N. Li, S. Hoogendoorn, M. Ruben, M. Verdoes, J. Guo, G.J. Boons, G.A. van der Marel, B.I. Florea, H.S. Overkleeft. 2012. Two-step bioorthogonal activity-based proteasome profiling using copper-free click reagents: a comparative study. 2011. Bioorg. Med. Chem. 20(2): 662-666.

193  Lakshminarayanan, V., P. Thompson, M.A. Wolfert, T. Buskas, J.M. Bradley, L.B. Pathangey,C.S. Madsen, P.A. Cohen, S.J. Gendler, and G.J. Boons. 2012. Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine. Proc. Natl. Acad. Sci. U. S. A. 109(1): 261-266.


192  Akimoto, Y.,Y. Miura, T. Toda, M.A. Wolfert, L. Wells, G.J. Boons, G.W. Hart, T. Endo, and H. Kawakami. 2011. Morphological changes in diabetic kidney are associated with increased O-GlcNAcylation of cytoskeletal proteins including alpha-actinin 4. Clin. Proteomics 8: 15.

191  Mo, K., T. Fang, S. Stalnaker, P.S. Kirby, M. Liu, L. Wells, M. Pierce, D.H. Live and G.J. Boons. 2011. Synthetic, structural and biosynthetic studies of an unusual phospho-glycopeptide derived from alpha-dystroglycan. J. Am. Chem. Soc. 133(36): 14418-14430.

190  Zhao, P., R. Viner, C.F. Teo, G.J. Boons, D. Horn, and L. Wells. 2011. Combining high-energy C-trap dissociation and electron transfer dissociation for protein O-GlcNAc modification site assignment. J. Proteome Res. 10(9): 4088-4104.

189  Mbua, N.E., J. Guo, M.A. Wolfert, R. Steet, and G.J. Boons. 2011. Strain-promoted alkyne-azide cycloadditions (SPAAC) reveal new features of glycoconjugate biosynthesis. ChemBioChem 12(12): 1912-1921.

188  Mir, M., J. Asong, X. Li, J. Cardot, G.J. Boons, and R.N. Husson. 2011. The extracytoplasmic domain of the Mycobacterium tuberculosis Ser/Thr kinase PknB binds specific muropeptides and is required for PknB localization. PLoS Pathog. 7(7): e1002182.

187  Li, X., J. Guo, J. Asong, M.A. Wolfert, and G.J. Boons. 2011. Multifunctional surface modification of gold-stabilized nanoparticles by bioorthogonal reactions. J. Am. Chem. Soc. 133(29): 11147-11153. Highlighted in ChemViews Magazine: News. 2011. Modular modification of gold nanoparticles. ChemViews Magazine of ChemPubSoc Europe, news 1236817.

186  Kashyap, D.R., M. Wang, L.H. Liu, G.J. Boons, D. Gupta, and R. Dziarski. 2011. Peptidoglycan recognition proteins kill bacteria by inducing suicide through protein-sensing two-component systems. Nat. Med. 17(6): 676-683.

185  Leach III, F.E., J.J. Wolff, Z. Xiao, M. Ly, T.N. Laremore, S. Arungundram, K. Al-Mafraji, A. Venot, G.J. Boons, R.J. Linhardt, I.J. Amster. 2011. Negative electron transfer dissociation Fourier transform mass spectrometry of glycosaminoglycan carbohydrates. Eur. J. Mass Spectrom. 17(2): 167-176.

184  Saile, E., G.J. Boons, T. Buskas, R.W. Carlson, E.L. Kannenberg, J.R. Barr, A.E. Boyer, M. Gallegos-Candela, and C.P. Quinn. 2011. Antibody responses to a spore carbohydrate antigen as a marker of non-fatal inhalation anthrax in rhesus macaques. Clin. Vaccine Immunol. 18(5): 743-748.

183  van der Wel, H., J.M. Johnson, Y. Xu, C.V. Karunaratne, K.D. Wilson, Y. Vohra, G.J. Boons, C.M. Taylor, B. Bendiak, and C.M. West. 2011. Requirements for Skp1 processing by cytosolic prolyl 4(trans)-hydroxylase and a-N-acetylglucosaminyltransferase enzymes involved in O2-signaling in Dictyostelium. Biochemistry 50(10): 1700-1713.

182  Oh H.B., F.E. Leach III, S. Arungundram, K. Al-Mafraji, A. Venot, G.J. Boons, and I.J. Amster. 2011. Multivariate analysis of electron detachment dissociation and infrared multiphoton dissociation mass spectra of heparan sulfate tetrasaccharides differing only in hexuronic acid stereochemistry. J. Am. Soc. Mass Spectrom. 22(3): 582-590.

181  Sanders, B.C.,F. Friscourt,P.A. Ledin,N.E. Mbua, S. Arumugam, J. Guo, T.J. Boltje, V.V. Popik, and G.J. Boons. 2011. Metal-free sequential [3+2]-dipolar cycloadditions using cyclooctynes and 1,3-dipoles of different reactivity. J. Am. Chem. Soc. 133(4): 949-957. Highlighted in JACS Beta: JACS Select #18, 2012. The Chemistry-Glycobiology Frontier (B. Imperiali, Guest Editor).

180  Boltje, T.J., J.H. Kim, J. Park, and G.J. Boons. 2011. Stereoelectronic effects determine oxacarbenium vs b-sulfonium ion mediated glycosylations. Org. Lett. 13(2): 284-287.

179  Ledin, P.A., F. Friscourt, J. Guo, and G.J. Boons. 2011. Convergent assembly and surface modification of multifunctional dendrimers by three consecutive click reactions. Chem. Eur. J. 17(3): 839-846.


178  Guo, J., G. Chen, X. Ning, M.A. Wolfert, X. Li, B. Xu, and G.J. Boons. 2010. Surface modification of polymeric micelles by strain-promoted alkyne-azide cycloadditions. Chem. Eur. J. 16(45): 13360-13366. Selected for frontispiece. Highlighted in Angew. Chem. Int. Ed.: Manova R., T.A. van Beek, and H. Zuilhof. 2011. Surface functionalization by strain-promoted alkyne-azide click reactions. Angew. Chem. Int. Ed. 50(24): 5428-5430.

177  Friscourt, F.and G.J. Boons. 2010. One-pot three-step synthesis of 1,2,3-triazoles by copper-catalyzed cycloaddition of azides with alkynes formed by a Sonogashira cross-coupling and desilylation. Org. Lett. 12(21): 4936-4939.

176  Boons G.J. 2010. Liposomes modified by carbohydrate ligands can target B-cells for the treatment of B-cell lymphomas. Expert Rev. Vaccines. 9(11): 1251-1256.

175  Boltje, T.J., C. Li, and G.J. Boons. 2010. Versatile set of orthogonal protecting groups for the preparation of highly branched oligosaccharides. Org. Lett. 12(20): 4636-4639.

174  Gaekwad J., Y. Zhang, W. Zhang, J, Reeves, M.A. Wolfert, and G.J. Boons. 2010. Differential induction of innate immune responses by synthetic lipid A derivatives.J. Biol. Chem. 285(38): 29375-29386.

173  Berghaus L.J., J.N. Moore, D.J. Hurley, M.L. Vandenplas, B.P. Fortes, M.A. Wolfert, and G.J. Boons. 2010. Innate immune responses of primary murine macrophage-lineage cells and RAW 264.7 cells to ligands of Toll-like receptors 2, 3, and 4. Comp. Immunol. Microbiol. Infect. Dis. 33(5): 443-454.

172  Boltje, T.J., J.H. Kim, J. Park, and G.J. Boons. 2010. Chiral-auxiliary-mediated 1,2-cis-glycosylations for the solid-supported synthesis of a biologically important branched a-glucan. Nat. Chem. 2(7): 552-557.

171  Teo C.F., S. Ingale, M.A. Wolfert, G.A. Elsayed,L.G. Nöt, J.C. Chatham,L. Wells, and G.J. Boons. 2010. Glycopeptide-specific monoclonal antibodies suggest new roles for O-GlcNAc. Nat. Chem. Biol. 6(5): 338-343.

170  Ning X., R.P. Temming, J. Dommerholt,J. Guo,D.B. Ania,M.F. Debets,M.A. Wolfert,G.J. Boons, and F.L. van Delft. 2010. Protein modification by strain-promoted alkyne-nitrone cycloaddition. Angew. Chem. Int. Ed. 49(17): 3065-3068. Selected as "Hot Paper".

169  Maiti, K.K., M. DeCastro, A.M. Abdel-Aal El-Sayed, M.I. Foote, M.A. Wolfert, and G.J. Boons. 2010. Chemical synthesis and proinflammatory responses of monophosphoryl lipid A adjuvant candidates. Eur. J. Org. Chem. (1): 80-91.


168  Arungundram,S., K. Al-Mafraji,J. Asong,F.E. Leach III, I.J. Amster,A. Venot, J.E. Turnbull,and G.J. Boons. 2009. Modular synthesis of heparan sulfate oligosaccharides for structure-activity relationship studies. J. Am. Chem. Soc. 131(47): 17394-17405. Highlighted in C&EN: Borman, S.A. 2009. Giant leap for obstinate targets. Sugar chemistry: Parallel combinatorial synthesis yields 12 hard-to-make oligosaccharides.Chemical & Engineering News, 87(47): 10.

167  Poloukhtine, A.A., N.E. Mbua, M.A. Wolfert, G.J. Boons, and V.V. Popik. 2009. Selective labeling of living cells by a photo-triggered click reaction J. Am. Chem. Soc. 131(43): 15769-15776.

166  Boltje, T.J., T. Buskas, and G.J. Boons. 2009. Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research. Nat. Chem. 1(8): 611-622.

165  Wang, Z.A., H. van der Wel, Y. Vohra, T. Buskas, G.J. Boons, and C.M. West. 2009. Role of a cytoplasmic dual-function glycosyltransferase in O2 regulation of development in Dictyostelium. J. Biol. Chem. 284(42): 28896-28904.

164  Buskas, T., P. Thompson, and G.J. Boons. 2009. Immunotherapy for cancer: Synthetic carbohydrate-based vaccines. Chem. Commun. (36): 5335-5349.

163  Vohra, Y., T. Buskas, and G.J. Boons. 2009. Rapid assembly of oligosaccharides: a highly convergent strategy for the assembly of a glycosylated amino acid derived from PSGL-1. J. Org. Chem. 74(16): 6064-6071.

162  Leoff C., E. Saile, J. Rauvolfova, C.P. Quinn, A.R. Hoffmaster, W. Zhong, A.S. Mehta, G.J. Boons, R.W. Carlson, and E.L. Kannenberg. 2009. Secondary cell wall polysaccharides of Bacillus anthracis are antigens that contain specific epitopes which cross-react with three pathogenic Bacillus cereus strains that caused severe disease, and other epitopes common to all the Bacillus cereus strains tested. Glycobiology 19(6): 665-673.

161  Marina-García N., L. Franchi, Y.G. Kim, Y. Hu, D.E. Smith, G.J. Boons, and G. Nunez. 2009. Clathrin- and dynamin-dependent endocytic pathway regulates muramyl dipeptide internalization and NOD2 activation. J. Immunol. 182(7): 4321-4327.

160  Asong, J., M.A. Wolfert, K. Maiti, D. Miller, and G.J. Boons. 2009. Binding and cellular activation studies reveal that Toll-like receptor 2 can differentially recognize peptidoglycan from Gram-positive and Gram-negative bacteria. J. Biol. Chem. 284(13): 8643-8653.

159  Chen, G., X. Ning, B. Park, G.J. Boons, and B. Xu. 2009. Simple, clickable protocol for atomic force microscopy tip modification and its application for trace ricin detection by recognition imaging. Langmuir 25(5): 2860-2864.

158  Ferrand, Y., E. Klein, N.P. Barwell, M.P. Crump, J. Jimenez-Barbera, C. Vicent, G.J. Boons, S. Ingale, and A.P. Davis. 2009. A synthetic lectin for O-linked b-N-acetylglucosamine. Angew. Chem. Int. Ed. 48(10): 1775-1779. Selected for inside cover picture.

157  Ingale, S., M.A. Wolfert, T. Buskas, and G.J. Boons. 2009. Increasing the antigenicity of synthetic tumor-associated carbohydrate antigens by targeting Toll-like receptors. ChemBioChem 10(3): 455-463.

156  Kuntz, D.A., W. Zhong, J. Guo, D.R. Rose, and G.J. Boons. 2009. The molecular basis of inhibition of Golgi a-mannosidase II by mannostatin A. ChemBioChem 10(2): 268-277.


155  Park, J., T.J. Boltje, and G.J. Boons. 2008. Direct and stereoselective synthesis of a-linked 2-deoxyglycosides. Org. Lett. 10(19): 4367-4370.

154  Zhang, Y., J. Gaekwad, M.A. Wolfert, and G.J. Boons. 2008. Synthetic tetra-acylated derivatives of lipid A from Porphyromonas gingivalis are antagonists of human TLR4. Org. Biomol. Chem. 6(18): 3371-3381.

153  Vohra, Y., M. Vasan, A. Venot, and G.J. Boons. 2008. One-pot synthesis of oligosaccharides by combining reductive openings of benzylidene acetals and glycosylations. Org. Lett. 10(15): 3247-3250.

152  Rauvolfova, J., A. Venot, and G.J. Boons. 2008. Chemo-enzymatic synthesis of C-9 acetylated sialosides. Carbohydr. Res. 343(10-11): 1605-1611.

151  Vasan M., J. Rauvolfova, M.A. Wolfert, C. Leoff, E.L. Kannenberg, C.P. Quinn, R.W. Carlson, and G.J. Boons. 2008. Chemical synthesis and immunological properties of oligosaccharides derived from the vegetative cell wall of Bacillus anthracis. ChemBioChem 9(11): 1716-1720.

150  Zhong W., D.A. Kuntz, B. Ember, H. Singh, K.W. Moremen, D.R. Rose, and G.J. Boons. 2008. Probing the substrate specificity of Golgi b-mannosidase II by use of synthetic oligosaccharides and a catalytic nucleophile mutant. J. Am. Chem. Soc. 130(28): 8975-8983.

149  Marina-Garcia, N., L. Franchi, Y.G. Kim, D. Miller, C. McDonald, G.J. Boons, and G. Nunez. 2008. Pannexin-1-mediated intracellular delivery of muramyl dipeptide induces caspase-1 activation via Cryopyrin/NLRP3 independently of Nod2. J. Immunol. 180(6): 4050-4057.

148  Ning, X., J. Guo, M.A. Wolfert, and G.J. Boons. 2008. Visualizing metabolically labeled glycoconjugates of living cells by copper-free and fast Huisgen cycloadditions. Angew. Chem. Int. Ed. 47(12): 2253-2255. Selected as a VIP paper.

147  Rao, Y., T. Buskas, A. Albert, M.A. O’Neill, M.G. Hahn, and G.J. Boons. 2008. Synthesis and immunological properties of a tetrasaccharide portion of the B side chain of rhamnogalacturonan II (RG-II). ChemBioChem 9(3): 381-388.

146  Zhang, Y., J. Gaekwad, M.A. Wolfert, and G.J. Boons. 2008. Innate immune responses of synthetic lipid A derivatives of Neisseria meningitidis. Chem. Eur. J. 14(2): 558-569.


145  Ingale, S., M.A. Wolfert, J. Gaekwad, T. Buskas, and G.J. Boons. 2007. Robust immune responses elicited by a fully synthetic three-component vaccine. Nat. Chem. Biol. 3(10): 663-667. Highlighted in Nat. Chem. Biol.: Bundle, D.R. 2007. A carbohydrate vaccine exceeds the sum of its parts. Nat. Chem. Biol. 3(10): 605-606.

144  Li, X., S. Wang, J. Qi, S.F. Echtenkamp, R. Chatterjee, M. Wang, G.J. Boons, R. Dziarski, and D. Gupta. 2007. Zebrafish peptidoglycan recognition proteins are bactericidal amidases essential for defense against bacterial infections. Immunity. 27(3): 518-529.

143  Rao, Y. and G.J. Boons. 2007. A highly convergent chemical synthesis of conformational epitopes of rhamnogalacturonan II. Angew. Chem. Int. Ed. 46(32): 6148-6151.

142  Zhang, Y., M.A. Wolfert, and G.J. Boons. 2007. The influence of the long chain fatty acid on the antagonistic activities of Rhizobium sin-1 lipid A. Bioorg. Med. Chem. 15(14): 4800-4812.

141  Vasan M., M.A. Wolfert, and G.J. Boons. 2007. Agonistic and antagonistic properties of a Rhizobium sin-1 lipid A modified by an ether-linked lipid. Org. Biomol. Chem. 5(13): 2087-2097.

140  Cho, S., Q. Wang, C.P. Swaminathan, D. Hesek, M. Lee, G.J. Boons, S. Mobashery, and R.A. Mariuzza. 2007. Structural insights into the bacterial mechanism of human peptidoglycan recognition proteins. Proc. Natl. Acad. Sci. U. S. A. 104(21): 8761-8766.

139  Park, J., S. Kawatkar, J.H. Kim, and G.J. Boons. 2007. Stereoselective glycosylations of 2-azido-2-deoxy-glucosides using intermediate sulfonium ions. Org. Lett. 9(10): 1959-1962.

138  Zhang, Y., J. Gaekwad, M.A. Wolfert, and G.J. Boons. 2007. Modulation of innate immune responses with synthetic lipid A derivatives. J. Am. Chem. Soc. 129(16): 5200-5216.

137  Liu, S., A. Venot, L. Meng, F. Tian, K.W. Moremen, G.J. Boons, and J.H. Prestegard. 2007. Spin-labeled analogs of CMP-NeuAc as NMR probes of the a-2,6-sialyltransferase ST6Gal I. Chem. Biol. 14(4): 409-418.

136  Wolfert, M.A., A. Roychowdhury, and G.J. Boons. 2007. Modifications of the structure of peptidoglycan is a strategy to avoid detection by nucleotide-binding oligomerization domain protein 1. Infect. Immun. 75(2): 706-713. Selected for IAI Spotlight.


135  Mehta, A., E. Saile, W. Zhong, T. Buskas, R. Carlson, E. Kannenberg, Y. Reed, C.P. Quinn, and G.J. Boons. 2006. Synthesis and antigenic analysis of the Bc1A glycoprotein oligosaccharide from the Bacillus anthracis exosporium. Chem. Eur. J. 12(36): 9136-9149. Selected for frontispiece.

134  Ingale, S., T. Buskas, and G.J. Boons. 2006. Synthesis of glyco(lipo)peptides by liposome-mediated native chemical ligationOrg. Lett. 8(25): 5785-5788.

133  Kim, J.H., H. Yang, V. Khot, D. Whitfield, and G.J. Boons. 2006. Stereoselective glycosylations using (R)- or (S)-(ethoxycarbonyl)benzyl chiral auxiliaries at C-2 of glycopyranosyl donors. Eur. J. Org. Chem. (22): 5007-5028. Selected for cover picture.

132  Zhu, X., S. Kawatkar, Y. Rao, and G.J. Boons. 2006. Practical approach for the stereoselective introduction of b-arabinofuranosides. J. Am. Chem. Soc. 128(36): 11948-11957. Highlighted in C&EN: Borman, S.A. 2007. Bacterial wall component made. Chemical & Engineering News 85(32): 6.

131  Alphey, M.S., A. Burton, M.D. Urbaniak, G.J. Boons, M.A. Ferguson, and W.N. Hunter. 2006. Tyrpanosoma brucei UDP-galactose-4’-epimerase in ternary complex with NAD+ and the substrate analogue UDP-4-deoxy-4-fluoro-a-d-galactose. Acta Crystallograph. Sect. F Struct. Biol. Cryst. Commun. 62(9): 829-834.

130  Guo, J., J. Asong, and G.J. Boons. 2006. Selective inhibition of glycosidases by feedback prodrugs. Angew. Chem. Int. Ed. 45(32): 5345-5348.

129  Buskas, T., S. Ingale, and G.J. Boons. 2006. Glycopeptides as versatile tools for glycobiology. Glycobiology 16(8): 113R-136R.

128  Kawatkar, S., D.A. Kuntz, R.J. Woods, D.R. Rose, and G.J. Boons. 2006. Structural basis of the inhibition of Golgi a-mannosidase II by mannostatin A and the role of the thiomethyl moiety in protein-ligand interactions. J. Am. Chem. Soc. 128(25): 8310-8319.

127  Buts, L., A. Garcia-Pino, A. Imberty, N. Amiot, G.J. Boons, S. Beeckmans, W. Versees, L. Wyns, and R. Loris. 2006. Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin. FEBS J. 273(11): 2407-2420.

126  Guan, R., P.H. Brown, C.P. Swaminathan, A. Roychowdhury, G.J. Boons, and R.A. Mariuzza. 2006. Crystal structure of human peptidoglycan recognition protein Ia bound to a muramyl pentapeptide from Gram-positive bacteria. Protein Science 15(5): 1199-1206.

125  Rao, Y., A. Venot, E.E. Swayze, R.H. Griffey, and G.J. Boons. 2006. Trisaccharide mimetics of the aminoglycoside antibiotic neomycin. Org. Biomol. Chem. 4(7): 1328-1337.

124  Swaminathan, C.P., P.H. Brown, A. Roychowdhury, Q. Wang, R. Guan, N. Silverman, W.E. Goldman, G.J. Boons, and R.A. Mariuzza. 2006. Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs). Proc. Natl. Acad. Sci. U. S. A. 103(3): 684-689.

123  Lee, H.S., M.A. Wolfert, Y. Zhang, and G.J. Boons. 2006. The 2-aminogluconate isomer of Rhizobium sin-1 lipid A can antagonize TNF-a production induced by enteric LPS. ChemBioChem 7(1): 140-148.


122  Kumar, S., A. Roychowdhury, B. Ember, Q. Wang, R. Guan, R.A. Mariuzza, and G.J. Boons. 2005. Selective recognition of synthetic lysine and meso-diaminopimelic acid-type peptidoglycan fragments by human peptidoglycan recognition protein Ia and S. J. Biol. Chem. 280(44): 37005-37012.

121  Roychowdhury, A., M.A. Wolfert, and G.J. Boons. 2005. Synthesis and pro-inflammatory properties of muramyl tripeptides containing lysine and diaminopimelic acid moieties. ChemBioChem 6(11): 2088-2097.

120  Buskas, T., S. Ingale, and G.J. Boons. 2005. Towards a fully synthetic carbohydrate-based anticancer vaccine: Synthesis and immunological evaluation of a lipidated glycopeptide containing the tumor-associated Tn-antigen. Angew. Chem. Int. Ed. 44(37): 5985-5988. Selected as a VIP paper. Highlighted in C&EN: Borman, S.A. 2005. Cancer vaccine is best in class: Three-part carbohydrate vaccine elicits strong anticancer response. Chemical & Engineering News 83(37): 10.

119  Buskas, T., Y. Li, and G.J. Boons. 2005. Synthesis of a dimeric Lewis antigen and the evaluation of the epitope specificity of antibodies elicited in mice. Chem. Eur. J. 11(18): 5457-5467.

118  Kim, J.H., H. Yang, J. Park, and G.J. Boons. 2005. A general strategy for stereoselective glycosylations. J. Am. Chem. Soc. 127(34): 12090-12097. Highlighted in C&EN and in Nature: Borman, S.A. 2005. New approach to glycosylation: Technique could facilitate one-pot and automated syntheses of carbohydrates. Chemical & Engineering News 83(34): 11; Flitsch, S.L. 2005. Synthetic chemistry: Glycosylation with a twist. Nature 437: 201-202.

117  Cato, D., T. Buskas, and G.J. Boons. 2005. Highly efficient stereospecific preparation of Tn and TF building blocks using thioglycosyl donors and the Ph2SO/Tf2O promoter system. J. Carbohydr. Chem. 24: 503-516.

116  Siriwardena, A., H. Strachan, S. El-Daher, G. Way, B. Winchester, J. Glushka, K. Moremen, and G.J. Boons. 2005. Potent and selective inhibition of class II a-d-mannosidase activity by a bicyclic sulfonium salt. ChemBioChem 6(5): 845-848.

115  Roychowdhury, A. and G.J. Boons. 2005. The synthesis of diaminopimelic acid containing peptidoglycan fragments using metathesis cross couplings. Tetrahedron Lett. 46(10): 1675-1678.

114  Majumdar, D., G.A. Elsayed, T. Buskas, and G.J. Boons. 2005. Synthesis of proteophosphoglycans of Leishmania major and Leishmania mexicana. J. Org. Chem. 70(5): 1691-1697.

113  Guan, R., A. Roychowdhury, B. Ember, S. Kumar, G.J. Boons, and R.A. Mariuzza. 2005. Crystal structure of a peptidoglycan recognition protein (PGRP) in complex with a muramyl tripeptide from Gram-positive bacteria. J. Endotoxin Res. 11(1): 41-46.

112  Kim, J.H., H. Yang, and G.J. Boons. 2005. Stereoselective glycosylations with chiral auxiliaries. Angew. Chem. Int. Ed. 44(6): 947-949. Highlighted in Nature: Research Highlights. 2005 Nature 436: 757.


111  Guan, R., A. Roychowdhury, B. Ember, S. Kumar, G.J. Boons, and R.A. Mariuzza. 2004. Structural basis for peptidoglycan binding by peptidoglycan recognition proteins. Proc. Natl. Acad. Sci. U. S. A. 101(49): 17168-17173.

110  Santhanam, B., M.A. Wolfert, J.N. Moore, and G.J. Boons. 2004. Synthesis and biological evaluation of a lipid A derivative that contains an aminogluconate moiety. Chem. Eur. J. 10(19): 4798-4807.

109  Santhanam, B. and G.J. Boons. 2004. Preparation of a lipid A derivative that contains a 27-hydroxyoctacosanoic acid moiety. Org. Lett. 6(19): 3333-3336.

108  Li, B., S.P. Kawatkar, S. George, H. Strachan, R.J. Woods, A. Siriwardena, K.W. Moremen, and G.J. Boons. 2004. Inhibition of Golgi mannosidase II with mannostatin A analogs: Synthesis, biological evaluation and structure activity relationship studies. ChemBioChem 5(9): 1220-1227.

107  Venot, A., E.E. Swayze, R.H. Griffey, and G.J. Boons. 2004. Disaccharide mimetics of the aminoglycoside antibiotic neamine. ChemBioChem 5(9): 1228-1236.

106  Buskas, T., Y.H. Li, and G.J. Boons. 2004. The immunogenicity of the tumor-associated antigen Lewisy may be suppressed by a bifunctional cross-linker required for coupling to a carrier protein. Chem. Eur. J. 10(14): 3517-3524.

105  Galan, M.C., A.P. Venot, and G.J.Boons. 2004. The design and synthesis of a selective inhibitor of fucosyltransferase VI. Org. & Biomol. Chem. 2(9): 1376-1380.

104  Galan, M.C., C.S. Dodsen, A.P. Venot, and G.J. Boons. 2004. Glycosyltransferase activity can be selectively modulated by chemical modificiations of acceptor substrates. Biorg. Med. Chem. Lett. 14(9):2205-2208.

103  Narendran P., K. Elsegood, N.J. Leech, W.M. Macindoe, G.J. Boons, and C.M. Dayan. 2004. Dendritic cell-based assays, but not mannosylation of antigen, improves detection of T-cell responses to proinsulin in type 1 diabetes. Immunology. 111(4): 422-429.

102  Watt, G. and G.J. Boons. 2004. A convergent strategy for the preparation of N-glycan core di, tri- and pentasaccharide thioaldoses for the site-specific glycosylation of peptides and proteins bearing free cysteines. Carbohydr. Res. 339(2): 181-193. Selected for cover picture.


101  Prabhu, A., A.P. Venot, and G.J. Boons. 2003. A new set of orthogonal protecting groups for the modular synthesis of heparan sulfate fragments. Org. Lett. 5(26): 4975-4978.

100  Galan, M.C., A.P. Venot, J. Glushka, A. Imberty, and G.J. Boons. 2003. Chemo-enzymatic synthesis of conformationally constrained oligosaccharides. Org. & Biomol. Chem. 1(22): 3891-3899.

99    Majumdar, D., T. Zhu, and G.J. Boons. 2003. Synthesis of oligosaccharides on soluble high-molecular-weight branched polymers in combination with purification by nanofiltration. Org. Lett. 5(20): 3591-3594.

98    Watt, G., J. Lund, M. Levens, V.S.K. Kolli, R. Jefferis, and G.J. Boons. 2003. Site-specific glycosylation of an aglycosylated human IgG1-Fc antibody protein generates neoglycoproteins with enhanced function. Chem. & Biol. 10(9): 807-814.

97    Elsayed, G.A. and G.J. Boons. 2003. Chemical synthesis of a-d-mannosylphosphate serine derivatives: A new class of synthetic glycopeptides. Synlett. (9): 1373-1375.

96    Pinhal-Enfield, G., M. Ramanathan, G. Hasko, S.N. Vogel, A.L. Salzman, G.J. Boons, and S.J. Leibovich. 2003. An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9, and adenosine A2A receptors. Am. J. Path. 163(2): 711-721.

95    Galan, M.C., A.P. Venot, and G.J. Boons. 2003. Glycosyltransferase activity can be modulated by small conformational changes of acceptor substrates. Biochemistry 42(28): 8522-8529.

94    Thobhani, S., B. Ember, A. Siriwardena, and G.J. Boons. 2003. Multivalency and the mode of action of bacterial sialidases. J. Am. Chem. Soc. 125(24): 7154-7155. Highlighted in C&EN:Science Concentrates. 2003. Polyvalent ligand inhibits cholera enzyme. Chemical & Engineering News 81(25): 38.

93    Demchenko, A.V, M.A. Wolfert, B. Santhanam, J.N. Moore, and G.J. Boons. 2003. Synthesis and biological evaluation of Rhizobium sin-1 lipid A derivatives. J. Am. Chem. Soc. 125(20): 6103-6112.


92    Geurtsen, R. and G.J. Boons. 2002. Chemoselective glycosylations of sterically hindered glycosyl acceptors. Tetrahedron Lett. 43(55): 9429-9431.

91    Arranz-Plaza, E., A.S. Tracy, A. Siriwardena, J.M. Pierce, and G.J. Boons. 2002. High-avidity, low-affinity multivalent interactions and the block to polyspermy in Xenopus laevis. J. Am. Chem. Soc. 124(44): 13035-13046.

90    Roychowdhury, A., A. Siriwardena, and G.J. Boons. 2002. A highly convergent approach for the synthesis of disaccharide repeating units of peptidoglycan. Tetrahedron Lett. 43(43):7805-7807.

89    Wolfert, M.A., T.F. Murray, G.J. Boons, and J.N. Moore. 2002. The origin of the synergistic effect of muramyl dipeptide with endotoxin and peptidoglycan. J. Biol. Chem. 277(42): 39179-39186.

88    Haller, M.F. and G.J. Boons. 2002. Selectively protected disaccharide building blocks for modular synthesis of heparin fragments. Eur. J. Org. Chem. (13): 2033-2038.

87    Elsayed, G.A., T. Zhu, and G.J. Boons. 2002. Demixing libraries of saccharides using a multi-linker approach in combination with a soluble polymeric support. Tetrahedron Lett. 43(26): 4691-4694.

86    Galan, M.C., A.P. Venot, J. Glushka, A. Imberty, and G.J. Boons. 2002. a-(2,6)-Sialyltransferase-catalyzed sialylations of conformationally constrained oligosaccharides. J. Am. Chem. Soc. 124(21): 5964-5973.

85    Geurtsen, R. and G.J. Boons. 2002. Regioselective glycosylations in solution and on soluble and insoluble polymeric support. Eur. J. Org. Chem. (9): 1473-1477.

84    De Meo, C., A.V. Demchenko, and G.J. Boons. 2002. Triflouroacetamido substituted sialyl donors for the preparation of sialyl galactosides. Aust. J. Chem. 55(1-2): 131-134.


83    Zhu, T. and G.J. Boons. 2001. Thioglycosides protected as trans-2,3-cyclic carbonates in chemoselective glycosylations. Org. Lett. 3(26): 4201-4203.

82    Clarke, C., R.J. Woods, J. Glushka, A. Cooper, M.A. Nutley, and G.J. Boons. 2001. Involvement of water in carbohydrate-protein binding. J. Am. Chem. Soc. 123(49): 12238-12247.

81    Kearns, D.B., A. Venot, P.J. Bonner, B. Stevens, G.J. Boons, and L.J. Shimkets. 2001. Identification of a developmental chemoattractant in Myxococcus xanthus through metabolic engineering. Proc. Natl. Acad. Sci. U. S. A. 98(24): 13990-13994.

80    Arranz, E. and G.J. Boons. 2001. The 2-(allyloxy) phenyl acetyl ester as a new relay protecting group for oligosaccharide synthesis. Tetrahedron Lett. 42(37): 6469-6471.

79    Siriwardena, A., M.R. Jørgensen, M.A. Wolfert, M.L. Vandenplas, J.N. Moore, and G.J. Boons. 2001. Synthesis and proinflammatory effects of peptidoglycan-derived neoglycopeptide polymers. J. Am. Chem. Soc. 123(33): 8145-8146.

78    De Meo, C., A.V. Demchenko, and G.J. Boons. 2001. A stereoselective approach for the synthesis of a-sialosides. J. Org. Chem. 66(16): 5490-5497.

77    McWatt, M. and G.J. Boons. 2001. Parallel combinatorial synthesis of glycodendrimers and their hydrogelation properties. Eur. J. Org. Chem. (13): 2535-2545.

76    Zhu, T. and G.J. Boons. 2001. A highly efficient synthetic strategy for polymeric support synthesis of Lex, Ley, and H-type 2 oligosaccharides. Chem. Eur. J. 7(11): 2382-2389.

75    Demchenko, A.V. and G.J. Boons. 2001. A highly convergent synthesis of a complex oligosaccharide derived from group B type III Streptococcus. J. Org. Chem. 66(8): 2547-2554.

74    Haller, M. and G.J. Boons. 2001. Towards a modular approach for heparin synthesis. J. Chem. Soc., Perkin Trans. 1(8): 814-822.


73    Boons, G.J. and A.V. Demchenko. Recent advances in O-sialylation. 2000. Chem. Rev. 100(12): 4539-4565.

72    Zhu, T. and G.J. Boons. 2000. Intermolecular aglycon transfer of ethyl thioglycosides can be prevented by judicious choice of protecting groups. Carbohydr. Res. 329(4): 709-715.

71    Zhu, T. and G.J. Boons. 2000. A novel and efficient synthesis of a dimeric Lex oligosaccharide on polymeric support. J. Am. Chem. Soc. 122(41): 10222-10223.

70    Bai, Y., G.J. Boons, A. Burton, M. Johnson, and M. Haller. 2000. Vinyl glycosides in oligosaccharide synthesis . 6. 3-Buten-2-yl 2-azido-2-deoxy glycosides and 3-buten-2-yl-phthalimido-2-deoxy glycosides as novel glycosyl donors. J. Carbohydr. Chem. 19(7): 939-958.

69    Belogi, G., T. Zhu, and G.J. Boons. 2000. Polymer-supported oligosaccharide synthesis by a loading-release-reloading strategy. Tetrahedron Lett. 41(36): 6969-6972.

68    Belogi, G., T. Zhu, and G.J. Boons. 2000. Polystyrylboronic acid as a reusable polymeric support for oligosaccharide synthesis. Tetrahedron Lett. 41(36): 6965-6968.

67    Reichel, F., A.M. Roelofsen, H.P.M. Geurts, S.J. van der Gaast, M.C. Feiters, and G.J. Boons. 2000. Synthesis and supramolecular characterization of a novel class of glycopyranosyl-containing amphiphiles. J. Org. Chem. 65(11): 3357-3366.

66    Zhu, T. and G.J. Boons. 2000. A new set of orthogonal protecting groups for oligosaccharide synthesis on a polymeric support. Tetrahedron: Asymmetry 11(1): 199-205.


65    Boons, G.J. 1999. Combinatorial approaches in oligosaccharide synthesis. Carbohydrates in Europe 27: 28-32.

64    Zhu, T. and G.J. Boons. 1999. A two directional and highly convergent approach for the synthesis of the tumor-associated antigen Globo-H. Angew. Chem. Int. Ed. 38(23): 3495-3497.

63    Geurtsen, R., F. Côté, M.G. Hahn, and G.J. Boons. 1999. Chemoselective glycosylation strategy for the convergent assembly of phytoalexin-elicitor active oligosaccharides and their photoreactive derivatives. J. Org. Chem. 64(21): 7828-7835.

62    Reichel, F., A.M. Roelofsen, H.P.M. Geurts, T.I. Hämäläinen, M.C. Feiters, and G.J. Boons. 1999. Stereochemical dependence of the self-assembly of the immunoadjuvants Pam3Cys and Pam3Cys-Ser. J. Am. Chem. Soc. 121(35): 7989-7997.

61    Demchenko, A.V., E. Rousson, and G.J. Boons. 1999. Stereoselective 1,2-cis-galactosylation assisted by remote neighboring group participation and solvent effects. Tetrahedron Lett. 40(36): 6523-6526.

60    Navarre, N., N. Amiot, A. van Oijen, A. Imberty, A. Poveda, J. Jiménez-Barbero, A. Cooper, M.A. Nutley, and G.J. Boons. 1999. Synthesis and conformational analysis of a conformationally constrained trisaccharide, and complexation properties with concanavalin A. Chem. Eur. J. 5(8): 2281-2294.

59    Demchenko, A.V. and G.J. Boons. 1999. A novel direct glycosylation approach for the synthesis of dimers of N-acetylneuraminic acid. Chem. Eur. J. 5(4): 1278-1283.


58    Johnson, M., C. Arles, and G.J. Boons. 1998. Vinyl glycosides in oligosaccharide synthesis .5. A latent-active glycosylation strategy for the preparation of branched trisaccharide libraries. Tetrahedron Lett. 39(52): 9801-9804.

57    Reichel F. and G.J. Boons. 1998. Sweet promise. Chemistry in Britain 34(9): 43-46.

56    Zhu, T. and G.J. Boons. 1998. A two-directional approach for the solid-phase synthesis of trisaccharide libraries. Angew. Chem. Int. Ed. 37(13-14): 1898-1900.

55    Bowers, S.G., D.M. Coe, and G.J. Boons. 1998. Application of the 2,5-dimethylpyrrole group as a new and orthogonal amine-protecting group in oligosaccharide synthesis. J. Org. Chem. 63(14): 4570-4571.

54    Demchenko, A.V. and G.J. Boons. 1998. A novel and versatile glycosyl donor for the preparation of glycosides of N-acetylneuraminic acid. Tetrahedron Lett. 39(19): 3065-3068.

53    Zhu, T. and G.J. Boons. 1998. A two directional glycosylation strategy for the convergent assembly of oligosaccharides. Tetrahedron Lett. 39(15): 2187-2190.

52    Macindoe, W.M., A.H. van Oijen, and G.J. Boons. 1998. A unique and highly facile method for synthesizing disulfide linked neoglycoconjugates: A new approach for remodelling of peptides and proteins. Chem. Commun. (7): 847-848.

51    Zhu, T. and G.J. Boons. 1998. Two-directional, convergent synthesis of a pentasaccharide that is involved in the hyperacute rejection response in xenotransplantation from pig to man. J. Chem. Soc., Perkin Trans. 1 (5): 857-861.


50    Gibson, R.R., R.P. Dickinson, and G.J. Boons. 1997. Vinyl glycosides in oligosaccharide synthesis .4. Glycosidase-catalysed preparation of substituted allyl glycosides. J. Chem. Soc., Perkin Trans. 1 (22): 3357-3360.

49    Geurtsen, R., D.S. Holmes, and G.J. Boons. 1997. Chemoselective glycosylations .2. Differences in size of anomeric leaving groups can be exploited in chemoselective glycosylations. J. Org. Chem. 62(23): 8145-8154.

48    Reichel, F., P.R. Ashton, and G.J. Boons. 1997. Synthetic carbohydrate-based vaccines: Synthesis of an l-glycero-d-manno-heptose antigen-T-epitope-lipopeptide conjugate. Chem. Commun. (21): 2087-2088.

47    Burton, A., P. Wyatt, and G.J. Boons. 1997. Preparation of fluorinated galactosyl nucleoside diphosphates to study the mechanism of the enzyme galactopyranose mutase. J. Chem. Soc., Perkin Trans. 1 (16): 2375-2382.

46    Demchenko, A.V., T. Stauch, and G.J. Boons. 1997. Solvent and other effects on the stereoselectivity of thioglycoside glycosidations. Synlett (7): 818-820.

45    Boons, G.J. and T. Zhu. 1997. Novel regioselective glycosylations for the convergent and chemoselective assembly of oligosaccharides. Synlett (7): 809-811.

44    Boons, G.J., S. Bowers, and D.M. Coe. 1997. Trityl ethers in oligosaccharide synthesis: A novel strategy for the convergent assembly of oligosaccharides. Tetrahedron Lett. 38(21): 3773-3776

43    Navarre, N., A.H. van Oijen, and G.J. Boons. 1997. The design and synthesis of a conformationally constrained trisaccharide for probing carbohydrate-protein interactions. Tetrahedron Lett. 38(11): 2023-2026.

42    Demchenko, A.V. and G.J. Boons. 1997. A highly convergent synthesis of a hexasaccharide derived from the oligosaccharide of group B type III Streptococcus. Tetrahedron Lett. 38(9): 1629-1632.


41    Boons, G.J., B. Heskamp, and F. Hout. 1996. Vinyl glycosides in oligosaccharide synthesis: A strategy for the preparation of trisaccharide libraries based on latent-active glycosylation. Angew. Chem. Int. Ed. 35(23-24): 2845-2847.

40    Boons, G.J. and T. Stauch. 1996. Stereoselectivity in glycosidic bond formation: Studies on the anomerisation of thioglycosides. Synlett (9): 906-908.

39    Boons, G.J. 1996. Synthetic oligosaccharides: Recent advances. Drug Discovery Today 1(8): 331-342.

38    Boons, G.J. and S. Isles. 1996. Vinyl glycosides in oligosaccharide synthesis .2. The use of allyl and vinyl glocosides in oligosaccharide synthesis. J. Org. Chem. 61(13): 4262-4271.

37    Boons, G.J. 1996. Recent developments in chemical oligosaccharide synthesis. Contemp. Org. Synth. 3(3): 173-200.

36    Boons, G.J., R. Eveson, S. Smith, and T. Stauch. 1996. A critical evaluation of the cationic coupling of 4-acetoxy-1,3-dioxanes. Synlett (6): 536-538.

35    Boons, G.J., A. Burton, and P. Wyatt. 1996. Glycosyl phosphates: A new latent-active anomeric phosphorylation strategy. Synlett (4): 310-312.

34    Parsons, N.J., G.J. Boons, P.R. Ashton, P.D. Redfern, P. Quirk, Y. Gao, C. Constantinidou, J. Patel, J. Bramley, J.A. Cole, and H. Smith. 1996. Lactic acid is the factor in blood cell extracts which enhances the ability of CMP-NANA to sialylate gonococcal lipopolysaccharide and induce serum resistance. Microb. Pathog. 20(2): 87-100.

33    Boons, G.J. 1996. Strategies in oligosaccharide synthesis. Tetrahedron 52(4): 1095-1121.

32    Boons, G.J., A. Burton, and S. Isles. 1996. A new procedure for the isomerisation of substituted and unsubstituted allyl ethers of carbohydrates. Chem. Commun. (2): 141-142.


31    Boons, G.J., R. Geurtsen, and E. Holmes. 1995. Chemoselective glycosylations .1. Differences in size of anomeric leaving groups can be exploited in chemoselective glycosylations. Tetrahedron Lett. 36(35): 6325-6328.

30    Boons, G.J., S. Isles, and P. Setälä. 1995. An improved procedure for the preparation of 1,6-anhydro sugars. Synlett(7): 755-756.

29    Boons, G.J., J.A. Clase, I.C. Lennon, S.V. Ley, and J. Staunton. 1995. Biosynthesis of tetronasin .4. Preparation of deuterium labelled C19-C26, C17-C26, C11-C26 and C3-C26 polyketide fragments as putative bisynthetic precursors of the ionophore antibiotic tetronasin (ICI 139603). Tetrahedron 51(18): 5417-5446.


28    Boons, G.J., R. Downham, K.S. Kim, S.V. Ley, and M. Woods. 1994. Dispiroketals in synthesis .10. Further reactions of dispoke protected lactate and glycolate enolates. Tetrahedron 50(24): 7157-7176.

27    Boons, G.J. and S. Isles. 1994. Vinyl glycosides in oligosaccharide synthesis .1. A new latent-active glycosylation strategy. Tetrahedron Lett. 35(21): 3593-3596.

26    Boons, G.J., I.C. Lennon, S.V. Ley, E.S.E. Owen, J. Staunton, and D.J. Wadsworth. 1994. Novel polyene cyclisation routes to the acyl tetronic acid ionophore tetronasin (ICI M139603). Tetrahedron Lett. 35(2): 323-326.

25    Boons, G.J., D.S. Brown, J.A. Clase, I.C. Lennon, and S.V. Ley. 1994. Two new routes to the C19-C26 tetrahydrofuran fragment of the acyl tetronic acid ionophore tetronasin (ICI M139603). Tetrahedron Lett. 35(2): 319-322.


24    Boons, G.J., P. Grice, R. Leslie, S.V. Ley, and L.L. Yeung. 1993. Dispiroketals in synthesis .5. A new opportunity for oligosaccharide synthesis using differentially activated glycosyl donors and acceptors. Tetrahedron Lett. 34(52): 8523-8526.

23    Boons, G.J., G.H. Castle, J.A. Clase, P. Grice, S.V. Ley, and C. Pinel. 1993. Selective acylation and alkylation reactions of diols using dibutyltin dimethoxide. Synlett (12): 913-914.

22    Boons, G.J., D.A. Entwistle, S.V. Ley, and M. Woods. 1993. Dispiroketals in synthesis .4. Enantioselective desymmertrization of glycerol using a C2-symmetric disubstituted bis-dihydropyran. Tetrahedron Lett. 34(35): 5649-5652.

21    Smid, P., F.J.M. Schippers, H.J.G. Broxterman, G.J.P.H. Boons, G.A. van der Marel, and J.H. van Boom. 1993. Use of (chloromethyl)dimethylphenylsilane in sugar chemistry. Stereo-controlled approach to destomic acid and 1-deoxy-nojirimycin. Recl. Trav. Chim. Pays-Bas 112(7-8): 451-456.

20    Ley, S.V., G.J. Boons, R. Leslie, M. Woods, and D.M. Hollinshead. 1993. Dispiroketals in synthesis .3. Selective protection of diequatorial vicinal diols in carbohydrates. Synthesis (7): 689-692.


19    Smid, P., W.P.A. Jörning, A.M.G. van Duuren, G.J.P.H. Boons, G. A. van der Marel, and J.H. van Boom. 1992. Stereoselective synthesis of a dimer containing an a-linked 2-acetamido-4-amino-2,4,6-trideoxy-d-galactopyranose (sugp) unit. J. Carbohydrate Chem. 11(7): 849-865.

18    Noort, D., N.C.R. van Straten, G.J.P.H. Boons, G.A. van der Marel, X. Bossuyt, N. Blanckaert, G.J. Mulder, and J.H. van Boom. 1992. Synthesis of a potential inhibitor of UDP-glycoronosyltransferase. Biomed. Chem. Lett. 2(6): 583-588.

17    van der Klein, P.A.M., W. Filemon, G.J.P.H. Boons, G.H. Veeneman, G.A. van der Marel, and J.H. van Boom. 1992. Synthesis of a cell wall component of Haemophilus (Actionobacillus) Pleuropneumoniae serotype 5. Tetrahedron 48(22): 4649-4658.

16    Boons, G.J.P.H., M. Overhand, G.A. van der Marel, and J.H. van Boom. 1992. Synthesis of two branched heptopyranoside (l,d-Hepp)-containing trisaccharides of the inner-core region of Citrobacter PCM 1487. Recl. Trav. Chim. Pays-Bas 111(3): 144-148.

15    Boons, G.J.P.H., F.L. van Delft, P.A.M. van der Klein, G.A. van der Marel, and J.H. van Boom. 1992. Synthesis of ld-Hepp and KDO containing disaccharide and tetrasaccharide derivatives of Neisseria meningitidis inner-core region via iodonium ion promoted glycosidations. Tetrahedron 48(5): 885-904.


14    Boons, G.J.P.H., R. Steyger, M. Overhand, G.A. van der Marel, and J.H. van Boom. 1991. Synthesis of naturally occurring ld-Hepp containing disaccharides. J. Carbohydr. Chem. 10(6): 995-1007.

13    Verheul, A.F.M., G.J.P.H. Boons, G.A. van der Marel, J.H. van Boom, H.J. Jennings, H. Snippe, J. Verhoef. P. Hoogerhout, and J.T. Poolman. 1991. Minimal oligosaccharide structures required for induction of immune responses against meningococcal immunotype L1, L2, and L3,7,9 lipopolysaccharides determined by using synthetic oligosaccharide-protein conjugates. Infect. Immun. 59(10): 3566-3573.

12    Boons, G.J.P.H., P. Hoogerhout, J.T. Poolman, G.A. van der Marel, and J.H. van Boom. 1991. Preparation of a well-defined sugar-peptide conjugate: A possible approach to a synthetic vaccine against Neisseria meningitidis. Bioorg. Med. Chem. Lett. 1(6): 303-308.


11    Verheul, A.F.M., H. Snippe, J. Verhoef, P. Hoogerhout, J.T. Poolman, G.J.P.H. Boons, G.A. van der Marel, and J.H. van Boom. 1991. Immunogenicity of meningococcal LPS derived oligosaccharide-protein conjugates using isolated and synthetic oligosaccharides. Neisseriae 1990: 301-306.

10    Boons, G.J.P.H., C.J.J. Elie, G.A. van der Marel, and J.H. van Boom. 1990. Use of (phenyldimethylsilyl)methoxymethyl and (phenyldimethylsilyl)methyl ethers as protecting groups for sugar hydroxyls. Tetrahedron Lett. 31(15): 2197-2200.

9      van der Klein P.A.M., G.J.P.H. Boons, G.H. Veeneman, G.A. van der Marel, and J.H. van Boom. 1990. Iodonium ion promoted cyclization: A convenient approach to glycosyl donors of 3-deoxy-d-manno-2-octulosonic acid (KDO). Synlett (6): 311-313.

8      Noort, D., G.H. Veeneman, G.J.P.H. Boons, G.A. van der Marel, G.J. Mulder, and J.H. van Boom. 1990. Iodonium ion promoted reactions at the anomeric C-2 centre of 1-methylene sugars. Synlett (4): 205-206.

7      Boons, G.J.P.H., P.A.M. van der Klein, G.A. van der Marel, and J.H. van Boom. 1990. A practical route toward the preparation of 4,5:7,8-di-O-isopropylidene KDO ethyl ester. Recl. Trav. Chim. Pays-Bas 109(4): 273-276.


6      van der Klein, P.A.M., G.J.P.H. Boons, G.H. Veeneman, G.A. van der Marel, and J. H. van Boom. 1989. An efficient route to 3-deoxy-d-manno-2-octulosonic acid (KDO) derivatives via a 1,4-cyclic sulfate approach. Tetrahedron Lett. 30(40): 5477-5480.

5      Boons, G.J.P.H., M. Overhand, G.A. van der Marel, and J.H. van Boom. 1989. Application of the dimethyl(phenyl)silyl group as a masked form of the hydroxy group in the synthesis of an l-glycero-a-d-manno-heptopyranoside-containing trisaccharide from the dephosphorylated inner core region of Neisseria meningitidis. Angew. Chem. Int. Ed. 28(11): 1504-1506.

4      Boons, G.J.P.H., M. Overhand, G.A. van der Marel, and J.H. van Boom. 1989. Synthesis of a trisaccharide of the inner core region of Citrobacter PCM 187 lipopolysaccharide that contains l-glycero-a-d-manno-heptopyranosyl units. Carbohydr. Res. 192: c1-c4.

3      Boons, G.J.P.H., G.A. van der Marel, J.T. Poolman, and J.H. van Boom. 1989. Synthesis of l-glycero-a-d-manno-heptopyranose-containing disaccharide derivatives of the Neisseria meningtitidis dephosphorylated inner-core region. Recl. Trav. Chim. Pays-Bas 108(10): 339-343.

2      Boons, G.J.P.H., G.A. van der Marel, and J. H. van Boom. 1989. A versatile and new highly stereoselective approach to the synthesis of l-glycero-d-manno-heptopyranosides. Tetrahedron Lett. 30(2): 229-232.


1      Boons, G.J.P.H., P.A.M. van der Klein, G.A. van der Marel, and J. H. van Boom. 1988. Synthesis of l-glycero-d-manno-heptose. Recl. Trav. Chim. Pays-Bas 107(7-8): 507-508.


Contributions to Edited Work (in reverse chronological order)

19    Gagarinov, I.A., A.D. Srivastava, G.J. Boons, and S. Visansirikul. 2017. Simplifying access to 3,4-di-O-acetyl-D-fucal (Chapter 24). In: Carbohydrate Chemistry: Proven Synthetic Methods, Volume 4 (C. Vogel and P. Murphy, eds). CRC Press, Taylor & Francis Group, Chapter 24.

18    Gagarinov, I.A., A.D. Srivastava, G.J. Boons, and Z. Wang. 2017. A multigram synthesis of phenyl 2-azido-3-O-benzyl-2-deoxy-4,6-O-benzylidene-1-thio-a-D-mannopyranoside (Chapter 21). In: Carbohydrate Chemistry: Proven Synthetic Methods, Volume 4 (C. Vogel and P. Murphy, eds). CRC Press, Taylor & Francis Group, Chapter 21.

17    Boltje, T.J., L. Liu, and G.J. Boons. 2016. Controlling anomeric selectivity, reactivity, and regioselectivity in glycosylations using protecting groups. In: Glycochemical Synthesis: Strategies and Applications (S.-C. Hung and M.M.L. Zulueta, eds). Wiley, Inc., Chapter 4.

16    West, C.M., H. van der Wel, Z. Chinoy, G.J. Boons, T.J. Gauthier, C.M. Taylor, and Y. Xu. 2015. Generating isoform-specific antibodies: Lessons from nucleocytoplasmic glycoprotein Skp1. In: Glycoscience: Biology and Medicine (N. Taniguchi, T. End, G.W. Hart, P.H. Seeberger, C.-H. Wong, eds) Springer, Japan, pp. 927-934.

15    Boltje, T.J., R. Benedict, and G.J. Boons. 2014. Highly stereoselective 1,2-cis-glycosylations employing the C-2 (S)-(phenylthiomethyl)benzyl ether as a chiral auxiliary. In: Carbohydrate Chemistry: Proven Synthetic Methods, Volume 2 (G. van der Marel and J. Codee, eds) CRC Press, Taylor and Francis Group, pp. 3-8.

14    Friscourt, F. and G.J. Boons. 2013. Bioorthogonal reactions for labeling glycoconjugates. In: Click Chemistry in Glycoscience: New Developments and Strategies (Z.J. Witczak and R. Bielski, eds) John Wiley & Sons, Inc., pp. 211-233.

13    Boons, G.J. 2010. Bioorthogonal chemical reporter methodology for visualization, isolation and analysis of glycoconjugates. In: Carbohydrate Chemistry: Chemical and Biological Approaches 36 (A. Pilar Rauter and T.K. Lindhorst, eds) RSC Publishing, Cambridge, pp. 152-167.

12    Buskas, T., P. Thompson, and G.J. Boons. 2008. Semisynthetic and fully synthetic carbohydrate-based cancer vaccines. In: Carbohydrate-Based Vaccines and Immunotherapies (Z. Guo and G.J. Boons, eds) John Wiley & Sons, Inc., Hoboken, NJ, pp. 263-311.

11    Zhong, W. and G.J. Boons. 2008. Thioglycosides in oligosaccharide synthesis. In: Handbook of Chemical Glycosylation: Advances in Stereoselectivity and Therapeutic Relevance (A.V. Demchenko, ed.) Wiley-VCH, pp. 261-302.

10    Kim, J.H., H. Yang, and G.J. Boons. 2007. Stereoselective glycosylations using chiral auxiliaries. In: Frontiers in Modern Carbohydrate Chemistry (A.V. Demchenko, ed.) American Chemical Society, Washington DC, pp.73-90.

9      De Meo, C., G.J. Boons, and A.V. Demchenko. 2007. Synthesis of glycosides of sialic acid. In: Comprehensive Glycoscience, Volume 1 (J.P. Kamerling, ed-in-chief, and G.J. Boons, Y.C. Lee, A. Suzuki, N. Taniguchi, and A.G.J. Voragen, eds.) Elsevier B.V., Amsterdam, pp. 583-604.

8      Boons, G.J. and B. Santhanam. 2003. Phathalic anhydride. In: Encyclopedia of Reagents for Organic Synthesis. John Wiley & Sons, Inc.

7      Boons, G.J. 2003. Sialic acid chemistry and biochemistry. In: Carbohydrate-based Drug Discovery (C.H. Wong, ed.) Wiley-VCH, pp. 55-102.

6      Boons, G.J. 2001. Glycosides as donors. In: Glycoscience: Chemistry and Chemical Biology I-III. (B. Fraser-Reid, J. Tatsuta, and J. Thiem, eds.) Springer-Verlag, Berlin Heidelberg, Volume I, pp. 551-581.

5      Boons, G.J. and T. Zhu. 2001. Two-direction glycosylations for the preparation of libraries of oligosaccharides. In: Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries (P. Seeberger, ed.) John Wiley & Sons, Inc. Press, pp. 201-211.

4      Boons, G.J. and R. Polt. 1997. The synthesis of N- and O-linked glycopeptides. In: Carbohydrate Chemistry (G.J. Boons, ed.) Blackie Academic & Professional, pp. 223-242.

3      Boons, G.J. 1997. Strategies and tactics in oligosaccharide synthesis. In: Carbohydrate Chemistry (G.J. Boons, ed.) Blackie Academic & Professional, pp.175-222.

2      Boons, G.J. and B. Heskamp. 1997. Functionalised saccharides. In: Carbohydrate Chemistry (G.J. Boons, ed.) Blackie Academic & Professional, pp. 46-83.

1      Boons, G.J. 1997. Structure, configuration and conformation of mono- and oligosaccharides. In: Carbohydrate Chemistry (G.J. Boons, ed.) Blackie Academic & Professional, pp.1-20.


Authored Book

Boons, G.J. and K.J. Hale. 2000. Organic Synthesis with Carbohydrates, Sheffield Academic Press Ltd., Sheffield, UK; Blackwell Science, Inc., Malden, Massachusetts (Postgraduate Chemistry Series).


Edited Books

Carbohydrate Chemistry (G.J. Boons, ed.) 1997. Blackie Academic & Professional (Professional Reference Book).

Comprehensive Glycoscience, From Chemistry to Systems Biology (4 Volume Set) (J.P. Kamerling, ed-in-chief, and G.J. Boons, Y.C. Lee, A. Suzuki, N. Taniguchi, and A.G.J. Voragen, eds.) 2007. Elsevier B.V., Amsterdam, The Netherlands.

Carbohydrate-Based Vaccines and Immunotherapies (Z. Guo and G.J. Boons, eds.) 2009. John Wiley & Sons, Inc. (Wiley Series in Drug Discovery and Development).

Carbohydrate Recognition: Biological Problems, Methods, and Applications (B. Wang and G.J. Boons, eds.) 2011.John Wiley & Sons, Inc. (Wiley Series in Drug Discovery and Development).