Publicaties
2023
Wetenschappelijke publicaties
Zuurveld, M., Diks, M. A. P., Kiliaan, P. C. J., Garssen, J., Folkerts, G., Van't Land, B., & Willemsen, L. E. M. (2023). Butyrate interacts with the effects of 2'FL and 3FL to modulate in vitro ovalbumin-induced immune activation, and 2'FL lowers mucosal mast cell activation in a preclinical model for hen's egg allergy. Frontiers in Nutrition, 10, Article 1305833. https://doi.org/10.3389/fnut.2023.1305833
https://dspace.library.uu.nl/bitstream/handle/1874/435263/fnut-10-1305833.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/435263/fnut-10-1305833.pdf?sequence=1
Gilbert, M. S., Cai, Y., Folkerts, G., Braber, S., & Gerrits, W. J. J. (2023). Effects of non-digestible oligosaccharides on inflammation, lung health and performance of calves. Journal of Dairy Science. Advance online publication. https://doi.org/10.3168/jds.2023-23887
Mavrogeni, M. E., Asadpoor, M., Judernatz, J. H., van Ark, I., Wösten, M. M. S. M., Strijbis, K., Pieters, R. J., Folkerts, G., & Braber, S. (2023). Protective Effects of Alginate and Chitosan Oligosaccharides against
Clostridioides difficile Bacteria and Toxin. Toxins, 15(10), 1-23. Article 586. https://doi.org/10.3390/toxins15100586
Memarzia, A., Saadat, S., Asgharzadeh, F., Behrouz, S., Folkerts, G., & Boskabady, M. H. (2023). Therapeutic effects of medicinal plants and their constituents on lung cancer, in vitro, in vivo and clinical evidence. Journal of Cellular and Molecular Medicine, 27(19), 2841-2863. https://doi.org/10.1111/jcmm.17936
Wang, L., Cai, Y., Garssen, J., Henricks, P. A. J., Folkerts, G., & Braber, S. (2023). Reply to: Gut Microbiota Dysbiosis and Chronic Obstructive Pulmonary Disease: A Question of Chicken and Egg. American Journal of Respiratory and Critical Care Medicine, 208(11), 1240-1241. https://doi.org/10.1164/rccm.202308-1418LE, https://doi.org/10.1164/rccm.202308-1418LE
https://dspace.library.uu.nl/bitstream/handle/1874/434309/wang-et-al-2023-reply-to-li-et-al.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/434309/wang-et-al-2023-reply-to-li-et-al.pdf?sequence=1
Seesing, M. F. J., Janssen, H. J. B., Geraedts, T. C. M., Weijs, T. J., van Ark, I., Leusink-Muis, T., Folkerts, G., Garssen, J., Ruurda, J. P., Nieuwenhuijzen, G. A. P., van Hillegersberg, R., & Luyer, M. D. P. (2023). Exploring the Modulatory Effect of High-Fat Nutrition on Lipopolysaccharide-Induced Acute Lung Injury in Vagotomized Rats and the Role of the Vagus Nerve. Nutrients, 15(10), Article 2327. https://doi.org/10.3390/nu15102327
Zhu, H., Cai, Y., Slimmen, L. J. M., de Bruijn, A. C. J. M., van Rossum, A. M. C., Folkerts, G., Braber, S., & Unger, W. W. J. (2023). Galacto-Oligosaccharides as an Anti-Infective and Anti-Microbial Agent for Macrolide-Resistant and -Sensitive Mycoplasma pneumoniae. FEMS Microbiology Immunology, 12(5), Article 659. https://doi.org/10.3390/pathogens12050659
Mortaz, E., Jamaati, H., K Dezfuli, N., Sheikhzade, H., Hashemian, S. M., Roofchayee, N. D., Dastan, F., Tabarsi, P., Folkerts, G., Garssen, J., Mumby, S., & Adcock, I. M. (2023). Changes in PD-1- and CTLA-4-bearing blood lymphocytes in ICU COVID-19 patients treated with Favipiravir/Kaletra or Dexamethasone/Remdesivir: a pilot study. Iranian Journal of Allergy, Asthma and Immunology, 22(1), 99-109. https://doi.org/10.18502/ijaai.v22i1.12012
Wang, L., Cai, Y., Garssen, J., Henricks, P. A. J., Folkerts, G., & Braber, S. (2023). The Bidirectional Gut-Lung Axis in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine, 207(9), 1145-1160. https://doi.org/10.1164/rccm.202206-1066TR
https://dspace.library.uu.nl/bitstream/handle/1874/428222/rccm.202206_1066tr.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/428222/rccm.202206_1066tr.pdf?sequence=1
Zuurveld, M., Ayechu-Muruzabal, V., Folkerts, G., Garssen, J., van‘t Land, B., & Willemsen, L. E. M. (2023). Specific Human Milk Oligosaccharides Differentially Promote Th1 and Regulatory Responses in a CpG-Activated Epithelial/Immune Cell Coculture. Biomolecules, 13(2), Article 263. https://doi.org/10.3390/biom13020263
Lian, P., Henricks, P. A. J., Wichers, H. J., Folkerts, G., & Braber, S. (2023). Differential Effects of Oligosaccharides, Antioxidants, Amino Acids and PUFAs on Heat/Hypoxia-Induced Epithelial Injury in a Caco-2/HT-29 Co-Culture Model. International Journal of Molecular Sciences, 24(2), 1-20. Article 1111. https://doi.org/10.3390/ijms24021111
Zuurveld, M., Díaz, C. B., Redegeld, F., Folkerts, G., Garssen, J., van’t Land, B., & Willemsen, L. E. M. (2023). An advanced in vitro human mucosal immune model to predict food sensitizing allergenicity risk: A proof of concept using ovalbumin as model allergen. Frontiers in Immunology, 13, 1-12. Article 1073034. https://doi.org/10.3389/fimmu.2022.1073034
Zuurveld, M., Kiliaan, P. C. J., van Grinsven, S. E. L., Folkerts, G., Garssen, J., Van't Land, B., & Willemsen, L. E. M. (2023). Ovalbumin-Induced Epithelial Activation Directs Monocyte-Derived Dendritic Cells to Instruct Type 2 Inflammation in T Cells Which Is Differentially Modulated by 2'-Fucosyllactose and 3-Fucosyllactose. Journal of Innate Immunity, 15(1), 222–239. https://doi.org/10.1159/000526528
2022
Wetenschappelijke publicaties
Kiaee, F., Jamaati, H., Shahi, H., Roofchayee, N. D., Varahram, M., Folkerts, G., Garssen, J., Adcock, I. M., & Mortaz, E. (2022). Immunophenotype and function of circulating myeloid derived suppressor cells in COVID-19 patients. Scientific Reports, 12(1), 1-12. Article 22570. https://doi.org/10.1038/s41598-022-26943-z
Cai, Y., Folkerts, G., & Braber, S. (2022). Non-Digestible Oligosaccharides: A Novel Treatment for Respiratory Infections? Nutrients, 14(23), 1-11. Article 5033. https://doi.org/10.3390/nu14235033
Pelgrim, C. E., van Ark, I., van Berkum, R. E., Schuitemaker-Borneman, A. M., Flier, I., Leusink-Muis, T., Janbazacyabar, H., Diks, M. A. P., Gosker, H. R., Kelders, M. C. J. M., Langen, R. C. J., Schols, A. M. W. J., Hageman, R. J. J., Braber, S., Garssen, J., Folkerts, G., van Helvoort, A., & Kraneveld, A. D. (2022). Effects of a nutritional intervention on impaired behavior and cognitive function in an emphysematous murine model of COPD with endotoxin-induced lung inflammation. Frontiers in Nutrition, 9, Article 1010989. https://doi.org/10.3389/fnut.2022.1010989
Mavrogeni, M. E., Asadpoor, M., Henricks, P. A. J., Keshavarzian, A., Folkerts, G., & Braber, S. (2022). Direct Action of Non-Digestible Oligosaccharides against a Leaky Gut. Nutrients, 14(21), Article 4699. https://doi.org/10.3390/nu14214699
Wang, L., van Iersel, L. E. J., Pelgrim, C. E., Lu, J., van Ark, I., Leusink-Muis, T., Gosker, H. R., Langen, R. C. J., Schols, A. M. W. J., Argilés, J. M., van Helvoort, A., Kraneveld, A. D., Garssen, J., Henricks, P. A. J., Folkerts, G., & Braber, S. (2022). Effects of Cigarette Smoke on Adipose and Skeletal Muscle Tissue: In Vivo and In Vitro Studies. Cells, 11(18), 1-20. Article 2893. https://doi.org/10.3390/cells11182893
Toutounchi, N. S., Braber, S., Land, B. V., Thijssen, S., Garssen, J., Folkerts, G., & Hogenkamp, A. (2022). Deoxynivalenol exposure during pregnancy has adverse effects on placental structure and immunity in mice model. Reproductive Toxicology, 112, 109-118. https://doi.org/10.1016/j.reprotox.2022.07.002
Wang, L., Pelgrim, C. E., Peralta Marzal, L. N., Korver, S., van Ark, I., Leusink-Muis, T., van Helvoort, A., Keshavarian, A., Kraneveld, A. D., Garssen, J., Henricks, P. A. J., Folkerts, G., & Braber, S. (2022). Changes in intestinal homeostasis and immunity in a cigarette smoke- and LPS-induced murine model for COPD: the lung-gut axis. American journal of physiology. Lung cellular and molecular physiology, 323(3), L266-L280. https://doi.org/10.1152/ajplung.00486.2021
Pelgrim, C. E., Wang, L., Peralta Marzal, L. N., Korver, S., van Ark, I., Leusink-Muis, T., Braber, S., Folkerts, G., Garssen, J., van Helvoort, A., & Kraneveld, A. D. (2022). Increased exploration and hyperlocomotion in a cigarette smoke and LPS induced murine model of COPD: linking pulmonary and systemic inflammation with the brain. American journal of physiology. Lung cellular and molecular physiology, 323(3), L251-L265. https://doi.org/10.1152/ajplung.00485.2021
Behrouz, S., Saadat, S., Memarzia, A., Sarir, H., Folkerts, G., & Boskabady, M. H. (2022). The Antioxidant: Anti-Inflammatory and Immunomodulatory Effects of Camel Milk. Frontiers in Immunology, 13, Article 855342. https://doi.org/10.3389/fimmu.2022.855342
Janbazacyabar, H., van Bergenhenegouwen, J., Varasteh, S., Garssen, J., Folkerts, G., & Braber, S. (2022). Repeated exposure of bronchial epithelial cells to particular matter increases allergen-induced cytokine release and permeability. Cytokine, 154, 1-11. Article 155878. https://doi.org/10.1016/j.cyto.2022.155878
Cai, Y., van Putten, J. P. M., Gilbert, M. S., Gerrits, W. J. J., Folkerts, G., & Braber, S. (2022). Galacto-oligosaccharides as an anti-bacterial and anti-invasive agent in lung infections. Biomaterials, 283, 1-18. Article 121461. https://doi.org/10.1016/j.biomaterials.2022.121461
Keulers, L., Dehghani, A., Knippels, L., Garssen, J., Papadopoulos, N., Folkerts, G., Braber, S., & van Bergenhenegouwen, J. (2022). Probiotics, prebiotics, and synbiotics to prevent or combat air pollution consequences: The gut-lung axis. Environmental pollution (Barking, Essex : 1987), 302, 1-14. Article 119066. https://doi.org/10.1016/j.envpol.2022.119066
Mortaz, E., Jamaati, H., Roofchayee, N. D., Sheikhzade, H., Mirenayat, M., Sadeghi, M., Lookzadeh, S., Dezfuli, N. K., Folkerts, G., Mumby, S., Garssen, J., & Adcock, I. M. (2022). Decreased serum levels of angiotensin converting enzyme (ACE)2 and enhanced cytokine levels with severity of COVID-19: normalisation upon disease recovery. Heliyon, 8(2), 1-8. Article e08957. https://doi.org/10.1016/j.heliyon.2022.e08957
Mortaz, E., Nomani, M., Adcock, I., Folkerts, G., & Garssen, J. (2022). Galactooligosaccharides and 2′-fucosyllactose can directly suppress growth of specific pathogenic microbes and affect phagocytosis of neutrophils. Nutrition, 96, 1-7. Article 111601. https://doi.org/10.1016/j.nut.2022.111601
Pelgrim, C. E., van Ark, I., Leusink-Muis, T., Brans, M. A. D., Braber, S., Garssen, J., van Helvoort, A., Kraneveld, A. D., & Folkerts, G. (2022). Intratracheal administration of solutions in mice; development and validation of an optimized method with improved efficacy, reproducibility and accuracy. Journal of Pharmacological and Toxicological Methods, 114, 1-7. Article 107156. https://doi.org/10.1016/j.vascn.2022.107156
Cai, Y., Gilbert, M. S., Gerrits, W. J. J., Folkerts, G., & Braber, S. (2022). Galacto-oligosaccharides alleviate lung inflammation by inhibiting NLRP3 inflammasome activation in vivo and in vitro. Journal of Advanced Research, 39, 305-318. https://doi.org/10.1016/j.jare.2021.10.013
2021
Wetenschappelijke publicaties
Janbazacyabar, H., van Bergenhenegouwen, J., Garssen, J., Leusink-Muis, T., Ark, I. V., van Daal, M. T., Folkerts, G., & Braber, S. (2021). Prenatal and Postnatal Cigarette Smoke Exposure Is Associated With Increased Risk of Exacerbated Allergic Airway Immune Responses: A Preclinical Mouse Model. Frontiers in Immunology, 12, 1-14. Article 797376. https://doi.org/10.3389/fimmu.2021.797376
Seyed Toutounchi, N., Braber, S., van’t Land, B., Thijssen, S., Garssen, J., Kraneveld, A. D., Folkerts, G., & Hogenkamp, A. (2021). Exposure to Deoxynivalenol During Pregnancy and Lactation Enhances Food Allergy and Reduces Vaccine Responsiveness in the Offspring in a Mouse Model. Frontiers in Immunology, 12, 1-15. Article 797152. https://doi.org/10.3389/fimmu.2021.797152
Verstegen, R. E. M., Kostadinova, A. I., Merenciana, Z., Garssen, J., Folkerts, G., Hendriks, R. W., & Willemsen, L. E. M. (2021). Dietary Fibers: Effects, Underlying Mechanisms and Possible Role in Allergic Asthma Management. Nutrients, 13(11), 1-32. Article 4153. https://doi.org/10.3390/nu13114153
van Daal, M. T., Folkerts, G., Garssen, J., & Braber, S. (2021). Pharmacological Modulation of Immune Responses by Nutritional Components. Pharmacological Reviews, 73(4), 198-232. https://doi.org/10.1124/pharmrev.120.000063
Cai, Y., Gilbert, M. S., Gerrits, W. J. J., Folkerts, G., & Braber, S. (2021). Anti-inflammatory properties of fructo-oligosaccharides in a calf lung infection model and in mannheimia haemolytica-infected airway epithelial cells. Nutrients, 13(10), 1-19. Article 3514. https://doi.org/10.3390/nu13103514
Asadpoor, M., Ithakisiou, G.-N., van Putten, J. P. M., Pieters, R. J., Folkerts, G., & Braber, S. (2021). Antimicrobial Activities of Alginate and Chitosan Oligosaccharides Against Staphylococcus aureus and Group B Streptococcus. Frontiers in Microbiology, 12, 1-15. Article 700605. https://doi.org/10.3389/fmicb.2021.700605
Toutounchi, N. S., Braber, S., Hogenkamp, A., Varasteh, S., Cai, Y., Wehkamp, T., Tims, S., Leusink-Muis, T., van Ark, I., Wiertsema, S., Stahl, B., Kraneveld, A. D., Garssen, J., Folkerts, G., & Van’T Land, B. (2021). Human milk oligosaccharide 3′-gl improves influenza-specific vaccination responsiveness and immunity after deoxynivalenol exposure in preclinical models. Nutrients, 13(9), Article 3190. https://doi.org/10.3390/nu13093190
Janbazacyabar, H., van Daal, M., Leusink-Muis, T., van Ark, I., Garssen, J., Folkerts, G., van Bergenhenegouwen, J., & Braber, S. (2021). The Effects of Maternal Smoking on Pregnancy and Offspring: Possible Role for EGF? Frontiers in Cell and Developmental Biology, 9, 1-15. Article 680902. https://doi.org/10.3389/fcell.2021.680902
Asadpoor, M., Varasteh, S., Pieters, R., Folkerts, G., & Braber, S. (2021). Differential effects of oligosaccharides on the effectiveness of ampicillin against Escherichia coli in vitro. PharmaNutrition, 16(6), 1-9. Article 100264. https://doi.org/10.1016/j.phanu.2021.100264
Mortaz, E., Bezemer, G., Alipoor, S. D., Varahram, M., Mumby, S., Folkerts, G., Garssen, J., & Adcock, I. M. (2021). Nutritional Impact and Its Potential Consequences on COVID-19 Severity. Frontiers in Nutrition, 8, 1-11. Article 698617. https://doi.org/10.3389/fnut.2021.698617
Lian, P., Braber, S., Varasteh, S., Wichers, H. J., & Folkerts, G. (2021). Hypoxia and heat stress affect epithelial integrity in a Caco-2/HT-29 co-culture. Scientific Reports, 11(1), Article 13186. https://doi.org/10.1038/s41598-021-92574-5
Wang, L., Pelgrim, C. E., Swart, D. H., Krenning, G., van der Graaf, A. C., Kraneveld, A. D., Leusink-Muis, T., van Ark, I., Garssen, J., Folkerts, G., & Braber, S. (2021). SUL-151 Decreases Airway Neutrophilia as a Prophylactic and Therapeutic Treatment in Mice after Cigarette Smoke Exposure. International Journal of Molecular Sciences, 22(9), 1-17. Article 4991. https://doi.org/10.3390/ijms22094991
Mortaz, E., Tabarsi, P., Jamaati, H., Dalil Roofchayee, N., Dezfuli, N. K., Hashemian, S. M., Moniri, A., Marjani, M., Malekmohammad, M., Mansouri, D., Varahram, M., Folkerts, G., & Adcock, I. M. (2021). Increased Serum Levels of Soluble TNF-α Receptor Is Associated With ICU Mortality in COVID-19 Patients. Frontiers in Immunology, 12, Article 592727. https://doi.org/10.3389/fimmu.2021.592727
Haksar, D., Asadpoor, M., Heise, T., Shi, J., Braber, S., Folkerts, G., Ballell, L., Rodrigues, J., & Pieters, R. J. (2021). Fighting Shigella by Blocking Its Disease-Causing Toxin. Journal of Medicinal Chemistry, 64(9), 6059-6069. https://doi.org/10.1021/acs.jmedchem.1c00152
Ayechu-Muruzabal, V., Xiao, L., Wehkamp, T., van Ark, I., Hoogendoorn, E. J., Leusink-Muis, T., Folkerts, G., Garssen, J., Willemsen, L. E. M., & Van’T Land, B. (2021). A fermented milk matrix containing postbiotics supports th1-and th17-type immunity in vitro and modulates the influenza-specific vaccination response in vivo in association with altered serum galectin ratios. Vaccines, 9(3), 1-17. Article 254. https://doi.org/10.3390/vaccines9030254
Pelgrim, C. E., van den Heuvel, J. M., Folkerts, G., Garssen, J., Maitland-van der Zee, A. H., & Kraneveld, A. D. (2021). Higher prescription of antidepressants and/or anxiolytics among chronic obstructive pulmonary disease patients. Therapeutic Advances in Respiratory Disease, 15, 1-9. https://doi.org/10.1177/1753466620961696
Asadpoor, M., Ithakisiou, G.-N., Henricks, P. A. J., Pieters, R., Folkerts, G., & Braber, S. (2021). Non-Digestible Oligosaccharides and Short Chain Fatty Acids as Therapeutic Targets against Enterotoxin-Producing Bacteria and Their Toxins. Toxins, 13(3), Article 175. https://doi.org/10.3390/TOXINS13030175
Li, M., van Esch, B. C. A. M., Henricks, P. A. J., Garssen, J., & Folkerts, G. (2021). IL-33 Is Involved in the Anti-Inflammatory Effects of Butyrate and Propionate on TNFα-Activated Endothelial Cells. International Journal of Molecular Sciences, 22(5), 1-15. Article 2447. https://doi.org/10.3390/ijms22052447
Richards, L. B., Li, M., Folkerts, G., Henricks, P. A. J., Garssen, J., & van Esch, B. C. A. M. (2021). Butyrate and propionate restore the cytokine and house dust mite compromised barrier function of human bronchial airway epithelial cells. International Journal of Molecular Sciences, 22(1), 1-16. Article 65. https://doi.org/10.3390/ijms22010065
2020
Wetenschappelijke publicaties
Mortaz, E., Tabarsi, P., Varahram, M., Folkerts, G., & Adcock, I. M. (2020). The Immune Response and Immunopathology of COVID-19. Frontiers in Immunology, 11, Article 2037. https://doi.org/10.3389/fimmu.2020.02037
Alipoor, S. D., Adcock, I. M., Tabarsi, P., Folkerts, G., & Mortaz, E. (2020). MiRNAs in tuberculosis: Their decisive role in the fate of TB. European Journal of Pharmacology, 886, 1-12. Article 173529. https://doi.org/10.1016/j.ejphar.2020.173529
https://dspace.library.uu.nl/bitstream/handle/1874/410123/1_s2.0_S001429992030621X_main.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/410123/1_s2.0_S001429992030621X_main.pdf?sequence=1
Mortaz, E., Malkmohammad, M., Jamaati, H., Naghan, P. A., Hashemian, S. M. R., Tabarsi, P., Varahram, M., Zaheri, H., Chousein, E. G. U., Folkerts, G., & Adcock, I. M. (2020). Silent hypoxia: higher NO in red blood cells of COVID-19 patients. BMC Pulmonary Medicine, 20(1), 1-6. Article 269. https://doi.org/10.1186/s12890-020-01310-8
Liu, D., Wagner, J. G., Harkema, J. R., Gerlofs-Nijland, M. E., Pinelli, E., Folkerts, G., Vandebriel, R. J., & Cassee, F. R. (2020). Livestock farm particulate matter enhances airway inflammation in mice with or without allergic airway disease. World Allergy Organization Journal, 13(4), Article 100114. https://doi.org/10.1016/j.waojou.2020.100114
Ghiamati Yazdi, F., Zakeri, A., Ark, I. V., Leusink-Muis, T., Braber, S., Soleimanian-Zad, S., & Folkerts, G. (2020). Crude Turmeric Extract Improves the Suppressive Effects of Lactobacillus rhamnosus GG on Allergic Inflammation in a Murine Model of House Dust Mite-Induced Asthma. Frontiers in Immunology, 11, Article 1092. https://doi.org/10.3389/fimmu.2020.01092
Asadpoor, M., Peeters, C., Henricks, P. A. J., Varasteh, S., Pieters, R. J., Folkerts, G., & Braber, S. (2020). Anti-pathogenic functions of non-digestible oligosaccharides in vitro. Nutrients, 12(6), Article 1789. https://doi.org/10.3390/nu12061789
Liu, D., Wagner, J. G., Mariman, R., Harkema, J. R., Gerlofs-Nijland, M. E., Pinelli, E., Folkerts, G., Cassee, F. R., & Vandebriel, R. J. (2020). Airborne particulate matter from goat farm increases acute allergic airway responses in mice. Inhalation Toxicology, 32(6), 265-277. https://doi.org/10.1080/08958378.2020.1781986
Zuurveld, M., van Witzenburg, N. P., Garssen, J., Folkerts, G., Stahl, B., van't Land, B., & Willemsen, L. E. M. (2020). Immunomodulation by Human Milk Oligosaccharides: The Potential Role in Prevention of Allergic Diseases. Frontiers in Immunology, 11, Article 801. https://doi.org/10.3389/fimmu.2020.00801
Cai, Y., Varasteh, S., van Putten, J. P. M., Folkerts, G., & Braber, S. (2020). Mannheimia haemolytica and lipopolysaccharide induce airway epithelial inflammatory responses in an extensively developed ex vivo calf model. Scientific Reports, 10(1), Article 13042. https://doi.org/10.1038/s41598-020-69982-0
Shahir, M., Mahmoud Hashemi, S., Asadirad, A., Varahram, M., Kazempour-Dizaji, M., Folkerts, G., Garssen, J., Adcock, I., & Mortaz, E. (2020). Effect of mesenchymal stem cell-derived exosomes on the induction of mouse tolerogenic dendritic cells. Journal of Cellular Physiology, 235(10), 7043-7055. https://doi.org/10.1002/jcp.29601
Komi, D. E. A., Mortaz, E., Amani, S., Tiotiu, A., Folkerts, G., & Adcock, I. M. (2020). The Role of Mast Cells in IgE-Independent Lung Diseases. Clinical Reviews in Allergy and Immunology, 58, 377–387. https://doi.org/10.1007/s12016-020-08779-5
Lian, P., Braber, S., Garssen, J., Wichers, H. J., Folkerts, G., Fink-Gremmels, J., & Varasteh, S. (2020). Beyond heat stress: Intestinal integrity disruption and mechanism-based intervention strategies. Nutrients, 12(3), Article 734. https://doi.org/10.3390/nu12030734
Folkerts, J., Redegeld, F., Folkerts, G., Blokhuis, B., van den Berg, M. P. M., de Bruijn, M. J. W., van IJcken, W. F. J., Junt, T., Tam, S.-Y., Galli, S. J., Hendriks, R. W., Stadhouders, R., & Maurer, M. (2020). Butyrate inhibits human mast cell activation via epigenetic regulation of FcεRI-mediated signaling. Allergy: European Journal of Allergy and Clinical Immunology, 75(8), 1966-1978. https://doi.org/10.1111/all.14254
Cai, Y., Folkerts, J., Folkerts, G., Maurer, M., & Braber, S. (2020). Microbiota-dependent and -independent effects of dietary fiber on human health. British Journal of Pharmacology, 177(6), 1363-1381. https://doi.org/10.1111/bph.14871
2019
Wetenschappelijke publicaties
Jeurink, P. V., Toutounchi, N. S., Acyabar, H. J., Folkerts, G., & Garssen, J. (2019). Immunopharmacology of Prebiotics and Probiotics. In Nijkamp and Parnham’s Principles of Immunopharmacology: Fourth revised and extended edition (pp. 545-559). Springer. https://doi.org/10.1007/978-3-030-10811-3_27
Malekmohammad, M., Folkerts, G., Kashani, B. S., Naghan, P. A., Dastenae, Z. H., Khoundabi, B., Garssen, J., Mortaz, E., & Adcock, I. M. (2019). Exhaled nitric oxide is not a biomarker for idiopathic pulmonary arterial hypertension or for treatment efficacy. BMC Pulmonary Medicine, 19(1), Article 188. https://doi.org/10.1186/s12890-019-0954-z
Toutounchi, N. S., Hogenkamp, A., Varasteh, S., Land, B. V. T., Garssen, J., Kraneveld, A. D., Folkerts, G., & Braber, S. (2019). Fusarium mycotoxins disrupt the barrier and induce IL-6 release in a human placental epithelium cell line. Toxins, 11(11), Article 665. https://doi.org/10.3390/toxins11110665
Xiao, L., van De Worp, W. R. P. H., Stassen, R., van Maastrigt, C., Kettelarij, N., Stahl, B., Blijenberg, B., Overbeek, S. A., Folkerts, G., Garssen, J., & van't Land, B. (2019). Human milk oligosaccharides promote immune tolerance via direct interactions with human dendritic cells. European Journal of Immunology, 49(7), 1001-1014. https://doi.org/10.1002/eji.201847971
Alipoor, S. D., Tabarsi, P., Varahram, M., Movassaghi, M., Dizaji, M. K., Folkerts, G., Garssen, J., Adcock, I. M., & Mortaz, E. (2019). Serum exosomal miRNAs are associated with active pulmonary tuberculosis. Disease Markers, 2019, Article 1907426. https://doi.org/10.1155/2019/1907426
Xiao, L., Engen, P. A., Leusink-Muis, T., Van Ark, I., Stahl, B., Overbeek, S. A., Garssen, J., Naqib, A., Green, S. J., Keshavarzian, A., Folkerts, G., & Van’t Land, B. (2019). The combination of 2-fucosyllactose with short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides that enhance influenza vaccine responses is associated with mucosal immune regulation in mice. Journal of Nutrition, 149(5), 856-869. https://doi.org/10.1093/jn/nxz006
Ghiamati Yazdi, F., Soleimanian-Zad, S., van den Worm, E., & Folkerts, G. (2019). Turmeric Extract: Potential Use as a Prebiotic and Anti-Inflammatory Compound? Plant Foods for Human Nutrition, 74(3), 293-299. https://doi.org/10.1007/s11130-019-00733-x
Kumawat, K., Geerdink, R. J., Hennus, M. P., Roda, M. A., Van Ark, I., Leusink-Muis, T., Folkerts, G., Van Oort-Jansen, A., Mazharian, A., Watson, S. P., Coenjaerts, F. E., Bont, L., & Meyaard, L. (2019). LAIR-1 limits neutrophilic airway inflammation. Frontiers in Immunology, 10(APR), Article 842. https://doi.org/10.3389/fimmu.2019.00842
Liu, D., Mariman, R., Gerlofs-Nijland, M. E., Boere, J. F., Folkerts, G., Cassee, F. R., & Pinelli, E. (2019). Microbiome composition of airborne particulate matter from livestock farms and their effect on innate immune receptors and cells. Science of the Total Environment, 688, 1298-1307. https://doi.org/10.1016/j.scitotenv.2019.06.217
https://dspace.library.uu.nl/bitstream/handle/1874/389149/1_s2.0_S0048969719327901_main.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/389149/1_s2.0_S0048969719327901_main.pdf?sequence=1
Janbazacyabar, H., van Bergenhenegouwen, J., Verheijden, K. A. T., Leusink-Muis, T., van Helvoort, A., Garssen, J., Folkerts, G., & Braber, S. (2019). Non-digestible oligosaccharides partially prevent the development of LPS-induced lung emphysema in mice. PharmaNutrition, 10, Article 100163. https://doi.org/10.1016/j.phanu.2019.100163
Alipoor, S. D., Adcock, I. M., Folkerts, G., Garssen, J., & Mortaz, E. (2019). A bioinformatics analysis of exosomal microRNAs released following mycobacterial infection. International Journal of Mycobacteriology, 8(3), 218-222. https://doi.org/10.4103/ijmy.ijmy_88_19
Mortaz, E., Zadian, S. S., Shahir, M., Folkerts, G., Garssen, J., Mumby, S., & Adcock, I. M. (2019). Does Neutrophil Phenotype Predict the Survival of Trauma Patients? Frontiers in Immunology, 10, Article 2122. https://doi.org/10.3389/fimmu.2019.02122
Abdul Roda, M., Xu, X., Abdalla, T. H., Sadik, M., Szul, T., Bratcher, P. E., Viera, L., Solomon, G. M., Wells, J. M., McNicholas, C. M., Redegeld, F. A., Folkerts, G., Blalock, J. E., & Gaggar, A. (2019). Proline-Glycine-Proline Peptides Are Critical in the Development of Smoke-Induced Emphysema. American Journal of Respiratory Cell and Molecular Biology, 61(5). https://doi.org/10.1165/rcmb.2018-0216OC
Pelgrim, C. E., Peterson, J. D., Gosker, H. R., Schols, A. M. W. J., van Helvoort, A., Garssen, J., Folkerts, G., & Kraneveld, A. D. (2019). Psychological co-morbidities in COPD: Targeting systemic inflammation, a benefit for both? European Journal of Pharmacology, 842, 99-110. https://doi.org/10.1016/j.ejphar.2018.10.001
2018
Wetenschappelijke publicaties
Dam, S. L., Folkerts, G., & Metselaar, M. H. M. (2018). Stroomschema voor keuze DOAC bij niet-valvulair atriumfibrilleren. Pharmaceutisch Weekblad, 153(38), 14-15.
Ricciardolo, F. L. M., Folkerts, G., Folino, A., & Mognetti, B. (2018). Bradykinin in asthma: Modulation of airway inflammation and remodelling. European Journal of Pharmacology, 827, 181-188. https://doi.org/10.1016/j.ejphar.2018.03.017
https://dspace.library.uu.nl/bitstream/handle/1874/375418/1_s2.0_S001429991830164X_main.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/375418/1_s2.0_S001429991830164X_main.pdf?sequence=1
Xiao, L., Van't Land, B., Engen, P. A., Naqib, A., Green, S. J., Nato, A., Leusink-Muis, T., Garssen, J., Keshavarzian, A., Stahl, B., & Folkerts, G. (2018). Human milk oligosaccharides protect against the development of autoimmune diabetes in NOD-mice. Scientific Reports, 8(1), Article 3829. https://doi.org/10.1038/s41598-018-22052-y
Taghavi, M., Mortaz, E., Khosravi, A., Vahedi, G., Folkerts, G., Varahram, M., Kazempour-Dizaji, M., Garssen, J., & Adcock, I. M. (2018). Zymosan attenuates melanoma growth progression, increases splenocyte proliferation and induces TLR-2/4 and TNF-α expression in mice. Journal of Inflammation, 15(5). https://doi.org/10.1186/s12950-018-0182-y
Xiao, L., Leusink-Muis, T., Kettelarij, N., van Ark, I., Blijenberg, B., Hesen, N. A., Stahl, B., Overbeek, S. A., Garssen, J., Folkerts, G., & Van't Land, B. (2018). Human Milk Oligosaccharide 2'-Fucosyllactose Improves Innate and Adaptive Immunity in an Influenza-Specific Murine Vaccination Model. Frontiers in Immunology, 9, Article 452. https://doi.org/10.3389/fimmu.2018.00452
Alipoor, S. D., Mortaz, E., Tabarsi, P., Marjani, M., Varahram, M., Folkerts, G., Garssen, J., & Adcock, I. M. (2018). miR-1224 Expression Is Increased in Human Macrophages after Infection with Bacillus Calmette-Guérin (BCG). Iranian Journal of Allergy, Asthma and Immunology, 17(3), 250-257. https://ijaai.tums.ac.ir/index.php/ijaai/article/view/1541
https://dspace.library.uu.nl/bitstream/handle/1874/375406/expression.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/375406/expression.pdf?sequence=1
Zheng, B., Morgan, M. E., van de Kant, H. J. G., Garssen, J., Folkerts, G., & Kraneveld, A. D. (2018). Corrigendum "Transcriptional modulation of pattern recognition receptors in chronic colitis in mice is accompanied with Th1 and Th17 response" [Biochem. Biophys. Rep. 12 (2017) 29-39]. Biochemistry and Biophysics Reports, 13, 147-148. https://doi.org/10.1016/j.bbrep.2018.02.002
Verheijden, K. A. T., Braber, S., Leusink-Muis, T., Jeurink, P. V., Thijssen, S., Kraneveld, A. D., Garssen, J., Folkerts, G., & Willemsen, L. E. M. (2018). The Combination Therapy of Dietary Galacto-Oligosaccharides With Budesonide Reduces Pulmonary Th2 Driving Mediators and Mast Cell Degranulation in a Murine Model of House Dust Mite Induced Asthma. Frontiers in Immunology, 9, Article 2419. https://doi.org/10.3389/fimmu.2018.02419
Mortaz, E., Amani, S., Mumby, S., Adcock, I. M., Movassaghi, M., Folkerts, J., Garssen, J., & Folkerts, G. (2018). Role of Mast Cells and Type 2 Innate Lymphoid (ILC2) Cells in Lung Transplantation. Science immunology, 2018, Article 2785971. https://doi.org/10.1155/2018/2785971
Brugman, S., Ikeda-Ohtsubo, W., Braber, S., Folkerts, G., Pieterse, C. M. J., & Bakker, P. A. H. M. (2018). A comparative review on microbiota manipulation: Lessons from fish, plants, livestock, and human research. Frontiers in Nutrition, 5, Article 80. https://doi.org/10.3389/fnut.2018.00080
Ikeda-Ohtsubo, W., Brugman, S., Warden, C. H., Rebel, J. M. J., Folkerts, G., & Pieterse, C. M. J. (2018). How can we define "optimal microbiota?": A comparative review of structure and functions of microbiota of animals, fish, and plants in agriculture. Frontiers in Nutrition, 5, Article 90. https://doi.org/10.3389/fnut.2018.00090
Li, M., van Esch, B. C. A. M., Henricks, P. A. J., Garssen, J., & Folkerts, G. (2018). Time and Concentration Dependent Effects of Short Chain Fatty Acids on Lipopolysaccharide- or Tumor Necrosis Factor α-Induced Endothelial Activation. Frontiers in Pharmacology, 9, Article 233. https://doi.org/10.3389/fphar.2018.00233
Li, M., van Esch, B. C. A. M., Wagenaar, G. T. M., Garssen, J., Folkerts, G., & Henricks, P. A. J. (2018). Pro- and anti-inflammatory effects of short chain fatty acids on immune and endothelial cells. European Journal of Pharmacology, 831, 52-59. https://doi.org/10.1016/j.ejphar.2018.05.003
Li, M., van Esch, B. C. A. M., Henricks, P. A. J., Folkerts, G., & Garssen, J. (2018). The Anti-inflammatory Effects of Short Chain Fatty Acids on Lipopolysaccharide- or Tumor Necrosis Factor α-Stimulated Endothelial Cells via Activation of GPR41/43 and Inhibition of HDACs. Frontiers in Pharmacology, 9, Article 533. https://doi.org/10.3389/fphar.2018.00533
2017
Wetenschappelijke publicaties
Mortaz, E., Alipoor, S. D., Movassaghi, M., Varahram, M., Ghorbani, J., Folkerts, G., Garssen, J., & Adcock, I. M. (2017). Water-pipe smoke condensate increases the internalization of Mycobacterium Bovis of type II alveolar epithelial cells (A549). BMC Pulmonary Medicine, 17(1), Article 68. https://doi.org/10.1186/s12890-017-0413-7
Xiao, L., Stahl, B., Folkerts, G., Garssen, J., Knippels, L., & Van’t Land, B. (2017). The immunological benefits of complex oligosaccharides in human milk. In Nutrition, Immunity, and Infection (pp. 145-158). CRC Press. https://doi.org/10.1201/9781315118901
Alipoor, S. D., Mortaz, E., Tabarsi, P., Marjani, M., Varahram, M., Folkerts, G., Garssen, J., & Adcock, I. M. (2017). miR-1224 Expression is Increased in Human Macrophage After Infection With Bacillus Calmette-Guerin (BCG). Iranian Journal of Allergy, Asthma and Immunology, 2017, 250-257. https://ijaai.tums.ac.ir/index.php/ijaai/article/view/1541
Chen, X., Orriols, M., Walther, F. J., Laghmani, E. H., Hoogeboom, A. M., Hogen-Esch, A. C. B., Hiemstra, P. S., Folkerts, G., Goumans, M.-J. T. H., Ten Dijke, P., Morrell, N. W., & Wagenaar, G. T. M. (2017). Bone Morphogenetic Protein 9 Protects against Neonatal Hyperoxia-Induced Impairment of Alveolarization and Pulmonary Inflammation. Frontiers in Physiology, 8, Article 486. https://doi.org/10.3389/fphys.2017.00486
Zheng, B., Morgan, M. E., van de Kant, H. J. G., Garssen, J., Folkerts, G., & Kraneveld, A. D. (2017). Transcriptional modulation of pattern recognition receptors in chronic colitis in mice is accompanied with Th1 and Th17 response. Biochemistry and Biophysics Reports, 12, 29-39. https://doi.org/10.1016/j.bbrep.2017.08.009
Xiao, L., Van't Land, B., van de Worp, W. R. P. H., Stahl, B., Folkerts, G., & Garssen, J. (2017). Early-Life Nutritional Factors and Mucosal Immunity in the Development of Autoimmune Diabetes. Frontiers in Immunology, 8, Article 1219. https://doi.org/10.3389/fimmu.2017.01219
Jamaati, H., Mortaz, E., Pajouhi, Z., Folkerts, G., Movassaghi, M., Moloudizargari, M., Adcock, I. M., & Garssen, J. (2017). Nitric Oxide in the Pathogenesis and Treatment of Tuberculosis. Frontiers in Microbiology, 8, Article 2008. https://doi.org/10.3389/fmicb.2017.02008
Ricciardolo, F. L. M., Sorbello, V., Folino, A., Gallo, F., Massaglia, G. M., Favatà, G., Conticello, S., Vallese, D., Gani, F., Malerba, M., Folkerts, G., Rolla, G., Profita, M., Mauad, T., Di Stefano, A., & Ciprandi, G. (2017). Identification of IL-17F/frequent exacerbator endotype in asthma. Journal of Allergy and Clinical Immunology. https://doi.org/10.1016/j.jaci.2016.10.034
2016
Wetenschappelijke publicaties
Verheijden, K. A. T., Braber, S., Leusink-Muis, T., Thijssen, S., Boon, L., Kraneveld, A. D., Garssen, J., Folkerts, G., & Willemsen, L. E. M. (2016). Regulatory T cell depletion abolishes the protective effect of dietary galactooligosaccharides on eosinophilic airway inflammation in house dust mite-induced asthma. Allergy: European Journal of Allergy and Clinical Immunology, 71, 229-230. https://doi.org/10.1111/all.12972
Athari, S. S., Pourpak, Z., Folkerts, G., Garssen, J., Moin, M., Adcock, I. M., Movassaghi, M., Ardestani, M. S., Moazzeni, S. M., & Mortaz, E. (2016). Conjugated Alpha-Alumina nanoparticle with vasoactive intestinal peptide as a Nano-drug in treatment of allergic asthma in mice. European Journal of Pharmacology, 791, 811-820. https://doi.org/10.1016/j.ejphar.2016.10.014
Richards, L. B., Li, M., van Esch, B. C. A. M., Garssen, J., & Folkerts, G. (2016). The effects of short-chain fatty acids on the cardiovascular system. PharmaNutrition, 4(2), 68-111. https://doi.org/10.1016/j.phanu.2016.02.001
Verheijden, K. A., Braber, S., Leusink-Muis, T., Thijssen, S., Boon, L., Kraneveld, A. D., Garssen, J., Folkerts, G., & Willemsen, L. E. (2016). Regulatory T Cell Depletion Abolishes the Protective Effect of Dietary Galacto-Oligosaccharides on Eosinophilic Airway Inflammation in House Dust Mite-Induced Asthma in Mice. Journal of Nutrition, 146(4), 831-837. https://doi.org/10.3945/jn.115.224402
Chen, X., Walther, F. J., van Boxtel, R., Laghmani, E. H., Sengers, R. M. A., Folkerts, G., DeRuiter, M. C., Cuppen, E., & Wagenaar, G. T. M. (2016). Deficiency or inhibition of lysophosphatidic acid receptor 1 protects against hyperoxia-induced lung injury in neonatal rats. Acta Physiologica, 216(3), 358–375. https://doi.org/10.1111/apha.12622
Zheng, B., van Bergenhenegouwen, J., van de Kant, H. J. G., Folkerts, G., Garssen, J., Vos, A. P., Morgan, M. E., & Kraneveld, A. D. (2016). Specific probiotic dietary supplementation leads to different effects during remission and relapse in murine chronic colitis. Benef Microbes, 7(2), 205-213. https://doi.org/10.3920/bm2015.0037
Ezzati Givi, M., Akbari, P., Boon, L., Puzovic, V. S., Bezemer, G. F. G., Ricciardolo, F. L. M., Folkerts, G., Redegeld, F. A., & Mortaz, E. (2016). Dendritic cells inversely regulate airway inflammation in cigarette smoke-exposed mice. American journal of physiology. Lung cellular and molecular physiology, 310(1), L95-L102. Article ajplung.00251.2014. https://doi.org/10.1152/ajplung.00251.2014
Verheijden, K. A. T., Willemsen, L. E. M., Braber, S., Leusink-Muis, T., Jeurink, P. V., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2016). The development of allergic inflammation in a murine house dust mite asthma model is suppressed by synbiotic mixtures of non-digestible oligosaccharides and Bifidobacterium breve M-16V. European Journal of Nutrition, 55(3), 1141-1151. https://doi.org/10.1007/s00394-015-0928-8
2015
Wetenschappelijke publicaties
Folkerts, G. (2015). An update on mycobacteria and the development of allergic diseases. International Journal of Mycobacteriology, 4(Supplement 1), 67. https://doi.org/10.1016/j.ijmyco.2014.11.013
Adcock, I. M., Hashemian, S. M. R., Mortaz, E., Masjedi, M. R., & Folkerts, G. (2015). Severity of acute respiratory distress syndrome resulting from tuberculosis correlates with bronchoalveolar lavage CXCL-8 expression. International Journal of Mycobacteriology. https://doi.org/10.1016/j.ijmyco.2014.11.039
Mortaz, E., Folkerts, G., Jamaati, H., Garssen, J., Marwan El-Sabbana, M., Sourosh, D., Velayati, A. A., & Adcock, I. M. (2015). Water pipe condense induces the release of CXCL-8 by human macrophage via reactive oxygen species and activation of NFKB. American Journal of Respiratory and Critical Care Medicine, 191, Article A4289.
Groenink, L., Folkerts, G., & Schuurman, H.-J. (2015). European Journal of Pharmacology, Special issue on translational value of animal models: Introduction. European Journal of Pharmacology, 759, 1-2. https://doi.org/10.1016/j.ejphar.2015.03.050
Chen, X., Walther, F. J., Sengers, R. M. A., Laghmani, E. H., Salam, A., Folkerts, G., Pera, T., & Wagenaar, G. T. M. (2015). Metformin attenuates hyperoxia-induced lung injury in neonatal rats by reducing the inflammatory response. American journal of physiology. Lung cellular and molecular physiology, 309(3), L262-L270. https://doi.org/10.1152/ajplung.00389.2014
Haghgoo, S. M., Allameh, A., Mortaz, E., Garssen, J., Folkerts, G., Barnes, P. J., & Adcock, I. M. (2015). Pharmacogenomics and targeted therapy of cancer: Focusing on non-small cell lung cancer. European Journal of Pharmacology, 754, 82-91. Article 000351953800012. https://doi.org/10.1016/j.ejphar.2015.02.029
Verheijden, K. A. T., Akbari, P., Willemsen, L. E. M., Kraneveld, A. D., Folkerts, G., Garssen, J., Fink-Gremmels, J., & Braber, S. (2015). Inflammation-induced expression of the alarmin interleukin 33 can be suppressed by galacto-oligosaccharides. International Archives of Allergy and Immunology, 167(2), 127-136. https://doi.org/10.1159/000437327
Mortaz, E., Adcock, I. M., Ricciardolo, F. L. M., Varahram, M., Jamaati, H., Velayati, A. A., Folkerts, G., & Garssen, J. (2015). Anti-Inflammatory Effects of Lactobacillus Rahmnosus and Bifidobacterium Breve on Cigarette Smoke Activated Human Macrophages. PLoS One, 10(8), Article e0136455. https://doi.org/10.1371/journal.pone.0136455
https://dspace.library.uu.nl/bitstream/handle/1874/325186/journal.pone.0136455.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/325186/journal.pone.0136455.pdf?sequence=1
Givi, M. E., Folkerts, G., Wagenaar, G. T. M., Redegeld, F. A., & Mortaz, E. (2015). Cigarette smoke differentially modulates dendritic cell maturation and function in time. Respiratory Research, 16, 131. https://doi.org/10.1186/s12931-015-0291-6
Hahn, C. S., Scott, D. W., Xu, X., Roda, M. A., Payne, G. A., Wells, J. M., Viera, L., Winstead, C. J., Bratcher, P., Sparidans, R. W., Redegeld, F. A., Jackson, P. L., Folkerts, G., Blalock, J. E., Patel, R. P., & Gaggar, A. (2015). The matrikine N-α-PGP couples extracellular matrix fragmentation to endothelial permeability. Science advances, 1(3). https://doi.org/10.1126/sciadv.1500175
Verheijden, K. A. T., Willemsen, L. E. M., Braber, S., Leusink-Muis, T., Delsing, D. J. M., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2015). Dietary galacto-oligosaccharides prevent airway eosinophilia and hyperresponsiveness in a murine house dust mite-induced asthma model. Respiratory Research, 16, 17. https://doi.org/10.1186/s12931-015-0171-0
Abdul Roda, M., Fernstrand, A. M., Redegeld, F. A., Blalock, J. E., Gaggar, A., & Folkerts, G. (2015). The matrikine PGP as a potential biomarker in COPD. American journal of physiology. Lung cellular and molecular physiology, 308(11), L1095-L1101. https://doi.org/10.1152/ajplung.00040.2015
Sorbello, V., Ciprandi, G., Di Stefano, A., Massaglia, G. M., Favatà, G., Conticello, S., Malerba, M., Folkerts, G., Profita, M., Rolla, G., & Ricciardolo, F. L. M. (2015). Nasal IL-17F is related to bronchial IL-17F/neutrophilia and exacerbations in stable atopic severe asthma. Allergy, 70(2), 236-240. https://doi.org/10.1111/all.12547
Overige resultaten
Wagenaar, G. T. M., Chen, X., Van Boxtel, R., Laghmani, E., Sengers, R., Folkerts, G., Cuppen, E., & Walther, F. (2015). Deficiency or inhibition of lysophosphatidic acid receptor 1 protects against hyperoxia-induced lung injury in neonatal rats.
Chen, X., Walther, F., Van Boxtel, R., Laghmani, E. H., Sengers, R., Folkerts, G., Cuppen, E., & Wagenaar, G. (2015). Deficiency or inhibition of lysophosphatidic acid receptor 1 protects against hyperoxia-induced lung injury in neonatal rats. https://doi.org/10.1183/13993003.congress2015.PA1866
Verheijden, K. A. T., Kraneveld, A. D., Garssen, J., Folkerts, G., & Willemsen, L. E. M. (2015). Dietary galacto-oligosaccharides reduce airway eosinophilia and enhance the Th2 suppressive effect of budesonide in house dust mite-induced asthma in mice. Allergy, 70, 44. https://doi.org/10.1111/all.12715
2014
Wetenschappelijke publicaties
Verheijden, K., Willemsen, L. E. M., Braber, S., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2014). The preventive effects of dietary galacto-oligosaccharides in a house dust mite-induced asthma model in mice. Allergy, 69, 467. https://doi.org/10.1111/all.12478
Vos, A. P., Nato, A. N., Bastiaans, J., Leusink-Muis, T., Stahl, B., Garssen, J., & Folkerts, G. (2014). Early supplementation of non-obese diabetic mice with oligosaccharides isolated from human milk reduces spontaneous autoimmune diabetes development later in life. Gastroenterology, 146(5), 840. https://doi.org/10.1016/S0016-5085(14)63052-3
Verheijden, K., Willemsen, L., Braber, S., Garssen, J., Kraneveld, A., & Folkerts, G. (2014). Dietary intervention with galactooligosaccharides is as effective or may be more effective as the treatment with the corticosteroid, budesonide, in a house dust mite-induced model of allergic asthma. Basic & Clinical Pharmacology & Toxicology, 115, 289-290.
Bezemer, G., Van Ark, I., Leusink Muis, T., Kraneveld, A., Garssen, J., & Folkerts, G. (2014). Acetate is more effective than a glucocorticoid steroid at preventing and reducing neutrophilic airway inflammation in a cigarette smoke induced mouse model for copd. Basic & Clinical Pharmacology & Toxicology, 115, 285.
Verheijden, K. A. T., Willemsen, L. E. M., Braber, S., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2014). A combination of fructo-oligosaccharides and Bifidobacterium breve M-16V suppresses airway resistance and inflammation in house dust mite allergic mice. Allergy, 69, 467-468. https://doi.org/10.1111/all.12478
Sagar, S., Vos, A. P., Morgan, M. E., Garssen, J., Georgiou, N. A., Boon, L., Kraneveld, A. D., & Folkerts, G. (2014). The combination of Bifidobacterium breve with non-digestible oligosaccharides suppresses airway inflammation in a murine model for chronic asthma. Biochimica et Biophysica Acta, 1842(4), 573-83. https://doi.org/10.1016/j.bbadis.2014.01.005
Sagar, S., Morgan, M. E., Chen, S., Vos, A. P., Garssen, J., van Bergenhenegouwen, J., Boon, L., Georgiou, N. A., Kraneveld, A. D., & Folkerts, G. (2014). Bifidobacterium breve and Lactobacillus rhamnosus treatment is as effective as budesonide at reducing inflammation in a murine model for chronic asthma. Respiratory Research, 15, 46. https://doi.org/10.1186/1465-9921-15-46
Zheng, B., van Bergenhenegouwen, J., Overbeek, S., van de Kant, H. J. G., Garssen, J., Folkerts, G., Vos, P., Morgan, M. E., & Kraneveld, A. D. (2014). Bifidobacterium breve attenuates murine dextran sodium sulfate-induced colitis and increases regulatory T cell responses. PLoS One, 9(5), e95441. https://doi.org/10.1371/journal.pone.0095441
Morgan, M. E., Koelink, P. J., Zheng, B., den Brok, M. H. M. G. M., van de Kant, H. J. G., Verspaget, H. W., Folkerts, G., Adema, G. J., & Kraneveld, A. D. (2014). Toll-like receptor 6 stimulation promotes T-helper 1 and 17 responses in gastrointestinal-associated lymphoid tissue and modulates murine experimental colitis. Mucosal Immunology, 7(5), 1266-77. https://doi.org/10.1038/mi.2014.16
Abdul Roda, M., Sadik, M., Gaggar, A., Hardison, M. T., Jablonsky, M. J., Braber, S., Blalock, J. E., Redegeld, F. A., Folkerts, G., & Jackson, P. L. (2014). Targeting prolyl endopeptidase with valproic acid as a potential modulator of neutrophilic inflammation. PLoS One, 9(5), Article e97594. https://doi.org/10.1371/journal.pone.0097594
Wagenaar, G. T. M., Sengers, R. M. A., Laghmani, E. H., Chen, X., Lindeboom, M. P. H. A., Roks, A. J. M., Folkerts, G., & Walther, F. J. (2014). Angiotensin II type 2 receptor ligand PD123319 attenuates hyperoxia-induced lung and heart injury at a low dose in newborn rats. American journal of physiology. Lung cellular and molecular physiology, 307(3), L261-72. https://doi.org/10.1152/ajplung.00345.2013
Verheijden, K. A. T., Henricks, P. A. J., Redegeld, F. A., Garssen, J., & Folkerts, G. (2014). Measurement of airway function using invasive and non-invasive methods in mild and severe models for allergic airway inflammation in mice. Frontiers in Pharmacology, 5, Article 190. https://doi.org/10.3389/fphar.2014.00190
Sagar, S., Folkerts, G., & Garssen, J. (2014). Prebiotics, probiotics and synbiotics for the management of respiratory disease. In Nutraceuticals and Functional Foods in Human Health and Disease Prevention (pp. 271-278). Taylor & Fancis/CRC press. https://doi.org/10.1201/b19308
Mortaz, E., Tabarasi, P., Seif, S., Karahrudi, M. A., Moniri, A., Kazempourdizaji, M., Adcock, I. M., Folkerts, G., Garssen, J., & Velayati, A. A. (2014). Concomitant occurrence of Mycobacterium tuberculosis and non-tuberculous Mycobacteria in a heterozygous carrier of chronic granulomatous patient. BioMed Research International.
Hashemian, S. M. R., Mortaz, E., Tabarsi, P., Jamaati, H., Maghsoomi, Z., Khosravi, A., Garssen, J., Masjedi, M. R., Velayati, A. A., Folkerts, G., Barnes, P. J., & Adcock, I. M. (2014). Elevated CXCL-8 expression in bronchoalveolar lavage correlates with disease severity in patients with acute respiratory distress syndrome resulting from tuberculosis. Journal of Inflammation (BioMed Central), 11, Article 11:21 . https://doi.org/10.1186/1476-9255-11-21
Folkerts, G., & Garssen, J. (2014). Pharma-Nutrition; An Overview. (AAPS Advances in the Pharmaceutical Sciences Series ed.) Springer. https://doi.org/10.1007/978-3-319-06151-1
Sagar, S., Folkerts, G., & Garssen, J. (2014). Pharma-Nutrition. In G. Folkerts, & J. Garssen (Eds.), Pharma-Nutrition; An Overview (pp. 3-8). (AAPS Advances in the Pharmaceutical Sciences Series). Springer. https://doi.org/10.1007/978-3-319-06151-1_1
Koelink, P. J., Overbeek, S. A., Braber, S., Morgan, M. E., Henricks, P. A. J., Abdul Roda, M., Verspaget, H. W., Wolfkamp, S. C., te Velde, A. A., Jones, C. W., Jackson, P. L., Blalock, J. E., Sparidans, R. W., Kruijtzer, J. A. W., Garssen, J., Folkerts, G., & Kraneveld, A. D. (2014). Collagen degradation and neutrophilic infiltration: a vicious circle in inflammatory bowel disease. Gut, 63, 578-587. https://doi.org/10.1136/gutjnl-2012-303252
Overige resultaten
Abdul Roda, M., Xu, X., Jackson, P. L., Folkerts, G., Redegeld, F., Wells, J. M., McNicholas-Bevensee, C. M., Viera, L., Bezemer, G., Blalock, J. E., & Gaggar, A. (2014). Prolyl endopeptidase inhibition ameliorates cardiovascular changes in a smoking mouse model.
Nato, A., Folkerts, G., Mortaz, E., Kraneveld, A., & Bezemer, G. (2014). The cigarette smoke-induced CXCL-8 release from human neutrophils is inhibited by TLR-9 antagonists. 299-300.
2013
Wetenschappelijke publicaties
Givi, M. E., Blokhuis, B. R., Da Silva, C. A., Adcock, I., Garssen, J., Folkerts, G., Redegeld, F. A., & Mortaz, E. (2013). Cigarette smoke suppresses the surface expression of c-kit and FcεRI on mast cells. Mediators of Inflammation, 2013, 813091. https://doi.org/10.1155/2013/813091
Overbeek, S. A., Kleinjan, M., Henricks, P. A. J., Kamp, V. M., Ricciardolo, F. L., Georgiou, N. A., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2013). Chemo-attractant N-acetyl proline-glycine-proline induces CD11b/CD18-dependent neutrophil adhesion. Biochimica et Biophysica Acta-General Subjects, 1830(1), 2188-2193. https://doi.org/10.1016/j.bbagen.2012.09.023
Overbeek, S. A., Braber, S., Koelink, P. J., Henricks, P. A. J., Mortaz, E., LoTam Loi, A. T., Jackson, P. L., Garssen, J., Wagenaar, G. T. M., Timens, W., Koenderman, L., Blalock, J. E., Kraneveld, A. D., & Folkerts, G. (2013). Cigarette Smoke-Induced Collagen Destruction; Key to Chronic Neutrophilic Airway Inflammation? PLoS One, 8(1), Article e55612. https://doi.org/10.1371/journal.pone.0055612
Morgan, M. E., Zheng, B., Koelink, P. J., van de Kant, H. J. G., Haazen, L. C. J. M., van Roest, M., Garssen, J., Folkerts, G., & Kraneveld, A. D. (2013). New Perspective on Dextran Sodium Sulfate Colitis: Antigen-Specific T Cell Development during Intestinal Inflammation. PLoS One, 8(7), Article e69936. https://doi.org/10.1371/journal.pone.0069936
Sagar, S., Morgan, M. E., Garssen, J., Georgiou, N., Kraneveld, A. D., Folkerts, G., & Vos, A. P. (2013). Treatment with a synbiotic concept reduces asthma-like symptoms and induces regulatory responses in a murine model of chronic allergic asthma. Allergy, 68, 669. https://doi.org/10.1111/all.12253
Sagar, S., Morgan, M. E., Vos, P., Garssen, J., Van Bergenhenegouwen, J., Georgiou, N., Kraneveld, A., & Folkerts, G. (2013). Bifidobacterium breve treatment is as effective as budesonide at reducing inflammation in a murine model of chronic asthma. Annals of Nutrition and Metabolism, 63, 1717. https://doi.org/10.1159/000354245
van Bergenhenegouwen, J., Plantinga, T. S., Joosten, L. A. B., Netea, M. G., Folkerts, G., Kraneveld, A. D., Garssen, J., & Vos, A. P. (2013). TLR2 & Co: a critical analysis of the complex interactions between TLR2 and coreceptors. Journal of Leukocyte Biology, 94(5), 885-902. https://doi.org/10.1189/jlb.0113003
Mortaz, E., Adcock, I. M., Folkerts, G., Barnes, P. J., Vos, A. P., & Garssen, J. (2013). Probiotics in the management of lung diseases. Mediators of Inflammation, 2013.
Zheng, B., Morgan, M. E., van de Kant, H. J. G., Garssen, J., Folkerts, G., & Kraneveld, A. D. (2013). Transcriptional modulation of pattern recognition receptors in acute colitis in mice. Biochimica et Biophysica Acta, 1832(12), 2162-2172.
Ezzati Givi, M., Blokhuis, B. R. J., Da Silva, C. A., Adcock, I., Garssen, J., Folkerts, G., Redegeld, F. A. M., & Mortaz, E. (2013). Cigarette smoke suppresses the surface expression of c-kit and FcepsilonRI on mast cells. Mediators of Inflammation, 2013.
van Noort, J. M., Bsibsi, M., Nacken, P. J., Gerritsen, W. H., Amor, S., Holtman, I. R., Boddeke, E., van Ark, I., Leusink-Muis, A., Folkerts, G., Hennink, W. E., & Amidi, M. (2013). Activation of an immune-regulatory macrophage response and inhibition of lung inflammation in a mouse model of COPD using heat-shock protein alpha B-crystallin-loaded PLGA microparticles. Biomaterials, 34(3), 831-40.
Sagar, S., Verheijden, K. A. T., Georgiou, N. A., Garssen, J., Kraneveld, A. D., Vos, A. P., & Folkerts, G. (2013). Differential regulation of inflammation and immunity in mild and severe experimental asthma. Mediators of Inflammation, 2013.
Overige resultaten
Abdul Roda, M., Bezemer, G., Redegeld, F., Gaggar, A., Blalock, E., & Folkerts, G. (2013). Prolyl endopeptidase inhibitors in neutrophilic lung inflammation in mice.
Givi, M. E., Folkerts, G., Redegeld, F., & Mortaz, E. (2013). Role of dendritic cell subsets in the early stage of cigarette smoke-induced lung inflammation.
Mortaz, E., Redegeld, F. A., Folkerts, G., & Ezzati Givi, N. (2013). Dendritic cells subsets in an acute model of cigarette smoke induced lung inflammation.
2012
Wetenschappelijke publicaties
Kraneveld, A. D., Sagar, S., Garssen, J., & Folkerts, G. (2012). The two faces of mast cells in food allergy and allergic asthma: the possible concept of Yin Yang. Biochimica et Biophysica Acta, 1822(1), 93-9. https://doi.org/10.1016/j.bbadis.2011.06.013
Mortaz, E., Adcock, I. M., Shafei, H., Masjedi, M. R., & Folkerts, G. (2012). Role of P2X7 Receptors in Release of IL-1β: A Possible Mediator of Pulmonary Inflammation. Tanaffos Journal, 11(2), 6-11.
Mortaz, E., Ezzati Givi, N., Da Silva, C. A., Folkerts, G., & Redegeld, F. A. (2012). A relation between TGF-β and mast cell tryptase in experimental emphysema models. Biochimica et Biophysica Acta. Molecular Basis of Disease, 1822(7), 1154-1160. https://doi.org/10.1016/j.bbadis.2012.03.006
ten Hoeve, A. L., Roda, M. A., Redegeld, F., Folkerts, G., Blalock, J. E., & Gaggar, A. (2012). Proline-glycine-proline as a potential biomarker in chronic obstructive pulmonary disease and cystic fibrosis. Tanaffos Journal, 11(2), 12-15.
Bezemer, G. F. G., Sagar, S., van Bergenhenegouwen, J., Georgiou, N. A., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2012). Dual role of toll-like receptors in asthma and chronic obstructive pulmonary disease. Pharmacological Reviews, 64(2), 337-358. https://doi.org/10.1124/pr.111.004622
Koelink, P. J., Overbeek, S. A., Braber, S., Morgan, M. E., Henricks, P. A., Verspaget, H. W., Wolfkamp, S. C., Te Velde, A. A., Jackson, P. L., Blalock, J. E., Garssen, J., Folkerts, G., & Kraneveld, A. D. (2012). Collagen proteolysis is important in neutrophilic intestinal auto-inflammation found in inflammatory bowel disease via proline-glycine-proline. Gastroenterology, 142(5), 883.
Sagar, S., Verheijden, K. A. T., Kraneveld, A. D., Georgiou, N., Garssen, J., & Folkerts, G. (2012). Different toll-like receptors (TLRs) and nod-like receptors (NLRs) expression profiles in lung tissue during mild and severe experimental asthma. American Journal of Respiratory and Critical Care Medicine, 185.
Sagar, S., Kraneveld, A. D., Georgiou, N. A., Garssen, J., & Folkerts, G. (2012). Probiotics and synbiotics: Effects on chronic asthma in mice. European Respiratory Journal, 40.
Mortaz, E., Silva, C., Folkerts, G., Garssen, J., & Redegeld, F. (2012). Cigarette smoke suppresses mast cell maturation and cytokine release independent of TLR4 signaling. European Respiratory Journal, 40.
Braber, S., Akbari, P., Kraneveld, A. D., Folkerts, G., Garssen, J., & Fink-Gremmels, J. (2012). Oligosaccharides: A promising new approach for minimizing the pathological effects of deoxynivalenol on the intestinal tract. Journal of Veterinary Pharmacology and Therapeutics, 35, 49-50. https://doi.org/10.1111/jvp.12004
Garssen, J., Folkerts, G., Redegeld, F., & Mortaz, E. (2012). Maturation and development of mast cells during cigarette smoke exposure. Allergy, 67, 636. https://doi.org/10.1111/all.12038
Braber, S., Thio, M., Blokhuis, B. R. J., Henricks, P. A. J., Koelink, P. J., Groot Kormelink, T., Bezemer, G. F. G., Kerstjens, H. A. M., Postma, D. S., Garssen, J., Kraneveld, A. D., Redegeld, F. A. M., & Folkerts, G. (2012). An association between neutrophils and immunoglobulin free light chains in the pathogenesis of chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine, 185(8), 817-24.
Ezzati Givi, M., Redegeld, F. A. M., Folkerts, G., & Mortaz, E. (2012). Dendritic cells in pathogenesis of COPD. Current Pharmaceutical Design, 18(16), 2329-35.
Ricciardolo, F. L. M., Sorbello, V., Benedetto, S., Defilippi, I., Sabatini, F., Robotti, A., Renswouw, D. C., Bucca, C., Folkerts, G., & de Rose, V. (2012). Bradykinin- and lipopolysaccharide-induced bradykinin B2 receptor expression, interleukin 8 release and "nitrosative stress" in bronchial epithelial cells BEAS-2B: role for neutrophils. European Journal of Pharmacology, 694(1-3), 30-8.
Koelink, P. J., Overbeek, S. A., Braber, S., de Kruijf, P., Folkerts, G., Smit, M. J., & Kraneveld, A. D. (2012). Targeting chemokine receptors in chronic inflammatory diseases: an extensive review. Pharmacology & Therapeutics, 133(1), 1-18. http://www.ncbi.nlm.nih.gov/pubmed/21839114
Sagar, S., Georgiou, N. A., Folkerts, G., Garssen, J., & Kraneveld, A. D. (2012). Role of Toll-Like Receptors in Asthma. In Toll-Like Receptors in Diseases of the Lung (pp. 26-45)
Mortaz, E., Ezzati Givi, M., Da Silva, C. A., Folkerts, G., & Redegeld, F. A. M. (2012). A relation between TGF-beta and mast cell tryptase in experimental emphysema models. Biochimica et Biophysica Acta. Molecular Basis of Disease, 1822(7), 1154-60.
van Bergenhenegouwen, B. J., Bezemer, G. F. G., Garssen, J., & Folkerts, G. (2012). COPD: Contribution of TLRs to disease pathogenesis. In Toll-Like Receptors in Diseases of the Lung (pp. 67-86)
Overige resultaten
Zheng, B., Van Bergenhenegouwen, J., Van De Kant, H., Garssen, J., Folkerts, G., Vos, P., Morgan, M. E., & Kraneveld, A. D. (2012). Bifidobacterium attenuates murine dextran sodium sulfate-induced colitis and increases regulatory t cell responses. 909.
Abdul Roda, M., Gaggar, A., Blalock, J. E., Jackson, P. L., Braber, S., Hardison, M. T., Redegeld, F., & Folkerts, G. (2012). Targeting prolyl endopeptidase in chronic obstructive pulmonary disease.
Mortaz, E., Ezzati Givi, N., Silva, C., Folkerts, G., & Redegeld, F. (2012). A relation between TGF-ß and mast cells tryptase in experimental emphysema models.
Verheijden, K., Henricks, P., Redegeld, F., Nijkamp, F., & Folkerts, G. (2012). A comparative study between penh and airway resistance in a mild and severe mouse model for allergic asthma.
Verheijden, K., Henricks, P., Redegeld, F., Nijkamp, F., & Folkerts, G. (2012). Comparison between Penh and airway resistance in a mild and severe mouse model for allergic asthma.
Bezemer, G., Diks, M., Vos, P., Garssen, J., Henricks, P., Kraneveld, A., & Folkerts, G. (2012). Synbiotics reduce airway inflammation and improve airway function in a mouse model for COPD.
2011
Wetenschappelijke publicaties
Garssen, J., & Folkerts, G. (2011). Foreword supplement. European Journal of Pharmacology, 668(SUPPL. 1). https://doi.org/10.1016/j.ejphar.2011.07.022
Kloek, J., Mortaz, E., Van Ark, I., Bloksma, N., Garssen, J., Nijkamp, F. P., & Folkerts, G. (2011). A whey-based glutathione-enhancing diet decreases allergen-induced airway contraction in a guinea-pig model of asthma. British Journal of Nutrition, 105(10), 1465-1470. https://doi.org/10.1017/S0007114510005337
van Eijl, S., Mortaz, E., Versluis, C., Nijkamp, F. P., Folkerts, G., & Bloksma, N. (2011). A low vitamin A status increases the susceptibility to cigarette smoke-induced lung emphysema in C57BL/6J mice. Journal of Physiology and Pharmacology, 62(2), 175-82.
Braber, S., Koelink, P. J., Henricks, P. A. J., Jackson, P. L., Nijkamp, F. P., Garssen, J., Kraneveld, A. D., Blalock, J. E., & Folkerts, G. (2011). Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown. American journal of physiology. Lung cellular and molecular physiology, 300(2), L255-L265. https://doi.org/10.1152/ajplung.00304.2010
Mortaz, E., Henricks, P. A. J., Kraneveld, A. D., Ezzati Givi, N., Garssen, J., & Folkerts, G. (2011). Cigarette smoke induces the release of CXCL-8 from human bronchial epithelial cells via TLRs and induction of the inflammasome. Biochimica et Biophysica Acta. Molecular Basis of Disease, 1812(9), 1104-1110. https://doi.org/10.1016/j.bbadis.2011.06.002
Zheng, B., Morgan, M. E., Van De Kant, H. J. G., Garssen, J., Folkerts, G., & Kraneveld, A. D. (2011). A survey of pathogen recognition receptors in the dextran sodium sulfate-induced mouse colitis model. European Journal of Pharmacology, 668, 28-29. https://doi.org/10.1016/j.ejphar.2011.09.260
Verheijden, K. A. T., Van Bergenhenegouwen, J., Garssen, J., Bezemer, G. F. G., Kraneveld, A. D., & Folkerts, G. (2011). Treatment with specific prebiotics or probiotics prevents the development of lung emphysema in a mouse model of COPD. European Journal of Pharmacology, 668, 12-13. https://doi.org/10.1016/j.ejphar.2011.09.220
van Eijl, S., Mortaz, E., Ferreira, A. F., Kuper, F., Nijkamp, F. P., Folkerts, G., & Bloksma, N. (2011). Humic acid enhances cigarette smoke-induced lung emphysema in mice and IL-8 release of human monocytes. Pulmonary Pharmacology & Therapeutics, 24(6), 682-689. https://doi.org/10.1016/j.pupt.2011.07.001
Nazary, M., Van Der Zee, H. H., Prens, E. P., Folkerts, G., & Boer, J. (2011). Pathogenesis and pharmacotherapy of Hidradenitis suppurativa. European Journal of Pharmacology, 672(1-3), 1-8. https://doi.org/10.1016/j.ejphar.2011.08.047
Van Bergenhenegouwen, J., Verheijden, K., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2011). Bifidobacterium breve and Lactobacillus rhamnosus prevent endotoxin-induced lung emphysema in mice. European Journal of Pharmacology, 668, 31-32. https://doi.org/10.1016/j.ejphar.2011.09.268
Overbeek, S. A., Braber, S., Henricks, P. A. J., Kleinjan, M., Kamp, V. M., Georgiou, N. A., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2011). Cigarette smoke induces β2-integrin-dependent neutrophil migration across human endothelium. Respiratory Research, 12, 75.
Braber, S., Overbeek, S. A., Koelink, P. J., Henricks, P. A. J., Zaman, G. J. R., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2011). CXCR2 antagonists block the N-Ac-PGP-induced neutrophil influx in the airways of mice, but not the production of the chemokine CXCL1. European Journal of Pharmacology, 668(3), 443-449. https://doi.org/10.1016/j.ejphar.2011.03.025
Kloek, J., Mortaz, E., van Ark, I., Lilly, C. M., Nijkamp, F. P., & Folkerts, G. (2011). Glutathione prevents the early asthmatic reaction and airway hyperresponsivness in Guinea pigs. Journal of Physiology and Pharmacology, 61, 67-72.
Overbeek, S. A., Henricks, P. A. J., Srienc, A. I., Koelink, P. J., de Kruijf, P., Lim, H. D., Smit, M. J., Zaman, G. J. R., Garssen, J., Nijkamp, F. P., Kraneveld, A. D., & Folkerts, G. (2011). N-acetylated Proline-Glycine-Proline induced G-protein dependent chemotaxis of neutrophils is independent of CXCL8 release. European Journal of Pharmacology, 668(3), 428-34.
Overbeek, S. A., Braber, S., Henricks, P. A. J., Kleinjan, M., Kamp, V. M., Georgiou, N. A., Garssen, J., Kraneveld, A. D., & Folkerts, G. (2011). Cigarette smoke induces beta2-integrin-dependent neutrophil migration across human endothelium. Respiratory Research, 12, 75.
Mortaz, E., Folkerts, G., & Redegeld, F. A. M. (2011). Mast cells and COPD. Pulmonary Pharmacology & Therapeutics, 24(4), 367-72.
Vakpublicaties
Garssen, J., & Folkerts, G. (2011). Foreword supplement. European Journal of Pharmacology, 668 Suppl.
Overige resultaten
Morgan, M. E., Zheng, B., Van De Kant, H., Folkerts, G., & Kraneveld, A. D. (2011). The development of TH17 responses towards gut antigens during colitis requires both intestinal inflammation and TLR stimulation. European Journal of Pharmacology, 496-497. https://doi.org/10.1016/j.ejphar.2011.09.210
Bezemer, G., Fillipov, D., Mortaz, E., Van Ark, I., Garssen, J., Kraneveld, A., Ossendorp, F., & Folkerts, G. (2011). Consequences of chronic pulmonary TLR9 activation in the lung and beyond.
Givi, M., Redegeld, F., Folkerts, G., & Mortaz, E. (2011). Cigarette smoke extract suppresses the maturation and function of bone marrow derived dendritic cells.
Morgan, M. E., Zheng, B., Van De Kant, H. J., Folkerts, G., Garssen, J., & Kraneveld, A. D. (2011). Toll-like receptor 2/6 stimulation in combination with intestinal inflammation leads to TH17 responses against orally administered antigens. 103-104. https://doi.org/10.1097/MPG.0b013e318224e326
Morgan, M. E., Zheng, B., Van Den Kant, H., Hazen, L., Van Roest, M., Folkerts, G., & Kraneveld, A. D. (2011). The development of Th17 responses towards gut antigens during colitis requires both intestinal inflammation and TLR2/6 stimulation. 7-8. https://doi.org/10.1016/j.ejphar.2011.09.210
Mortaz, E., Henricks, P., Kraneveld, A., Givi, M., Garssen, J., & Folkerts, G. (2011). Cigarette smoke induces the release of CXCL-8 from human bronchial epithelial cells via TLRs and the induction of inflammasome.
Mortaz, E., Folkerts, G., Kraneveld, A., Kool, M., Lambrecht, B., Garssen, J., & Redegeld, F. (2011). Role of inflammasome signaling in development and function of mast cells.
Mortaz, E., Van Bergenhenegouwen, J., Georgiou, N., Garssen, J., Kraneveld, A., & Folkerts, G. (2011). Lactobacillus rhamnosus and Bifidobacterium breve suppress cigarette smoke induced CXCL-8 release by human macrophages. 11-12. https://doi.org/10.1016/j.ejphar.2011.09.219
Mortaz, E., Ezzati Givi, N., Henricks, P., Kraneveld, A., & Folkerts, G. (2011). Regulation of the release of CXCL-8 from human bronchial epithelial cells via TLRs and induction of the inflammasome. 287. https://doi.org/10.1016/j.clinbiochem.2011.08.716
Sagar, S., Verheijden, K. A. T., Kraneveld, A. D., Georgiou, N., Folkerts, G., & Garssen, J. (2011). An expression survey of toll-like receptors (TLRs) and nod-like receptors (NLRs) in allergic asthma.
Overbeek, S., Braber, S., Henricks, P., Kleinjan, M., Kamp, V., Georgiou, N., Garssen, J., Kraneveld, A., & Folkerts, G. (2011). Cigarette smoke induces β2-integrin-dependent neutrophil migration across human umbilical vein endothelium.
2010
Wetenschappelijke publicaties
de Kruijf, P., Lim, H. D., Overbeek, S. A., Zaman, G. J. R., Kraneveld, A. D., Folkerts, G., Leurs, R., & Smit, M. J. (2010). The collagen-breakdown product N-acetyl-Proline-Glycine-Proline (N-α-PGP) does not interact directly with human CXCR1 and CXCR2. European Journal of Pharmacology, 643(1), 29-33. https://doi.org/10.1016/j.ejphar.2010.06.017
Hougee, S., Vriesema, A. J. M., Wijering, S. C., Knippels, L. M. J., Folkerts, G., Nijkamp, F. P., Knol, J., & Garssen, J. (2010). Oral treatment with probiotics reduces allergic symptoms in ovalbumin-sensitized mice: A bacterial strain comparative study. International Archives of Allergy and Immunology, 151(2), 107-117. https://doi.org/10.1159/000236000
Mortaz, E., Folkerts, G., Nijkamp, F. P., & Henricks, P. A. J. (2010). ATP and the pathogenesis of COPD. European Journal of Pharmacology, 638(1-3), 1-4. https://doi.org/10.1016/j.ejphar.2010.04.019
Sarir, H., Mortaz, E., Janse, W. T., Ezzati Givi, N., Nijkamp, F. P., & Folkerts, G. (2010). IL-8 production by macrophages is synergistically enhanced when cigarette smoke is combined with TNF-α. Biochemical Pharmacology, 79(5), 698-705. https://doi.org/10.1016/j.bcp.2009.10.001
Ezzati Givi, N., Folkerts, G., Redegeld, F., & Mortaz, E. (2010). Cross-linking IgE with antigen induces proinflammatory cytokine production via inflammasome signaling. Allergy, 65, 127-128. https://doi.org/10.1111/j.1398-9995.2010.02392.x
Folkerts, G., Blalock, E., Braber, S., Kraneveld, A., & Nijkamp, F. (2010). CXC chemokines and antagonists in chronic airway inflammation. Basic & Clinical Pharmacology & Toxicology, 107, 35-36. https://doi.org/10.1111/j.1742-7843.2010.00598-2.x
De Kruijf, P., Koelink, P., Zheng, B., Folkerts, G., Leurs, R., Chazot, P. L., Lethbridge, N. L., Kraneveld, A. D., & Smit, M. J. (2010). Expression profiling of chemotactic receptors in inflammatory diseases. Inflammation Research, 59, 347. https://doi.org/10.1007/s00011-010-0263-8
Mortaz, E., Adcock, I. M., Ito, K., Kraneveld, A. D., Nijkamp, F. P., & Folkerts, G. (2010). Cigarette smoke induces CXCL8 production by human neutrophils via activation of TLR9 receptor. European Respiratory Journal, 36(5), 1143-54.
Braber, S., Henricks, P. A. J., Nijkamp, F. P., Kraneveld, A. D., & Folkerts, G. (2010). Inflammatory changes in the airways of mice caused by cigarette smoke exposure are only partially reversed after smoking cessation. Respiratory Research, 11(99), 1-11. http://respiratory-research.com/content/11/1/99
Braber, S., Verheijden, K. A. T., Henricks, P. A. J., Kraneveld, A. D., & Folkerts, G. (2010). A comparison of fixation methods on lung morphology in a murine model of emphysema. American journal of physiology. Lung cellular and molecular physiology, 299(6), L843-51.
de Kruijf, P., Lim, H. D., Overbeek, S. A., Zaman, G. J. R., Kraneveld, A. D., Folkerts, G., Leurs, R., & Smit, M. J. (2010). The collagen-breakdown product N-acetyl-Proline-Glycine-Proline (N-alpha-PGP) does not interact directly with human CXCR1 and CXCR2. European Journal of Pharmacology, 643(1), 29-33.
Kloek, J., Mortaz, E., van Ark, I., Lilly, C. M., Nijkamp, F. P., & Folkerts, G. (2010). Glutathione prevents the early asthmatic reaction and airway hyperresponsiveness in guinea pigs. Journal of Physiology and Pharmacology, 61(1), 67-72.
Sarir, H., Mortaz, E., Janse, W. T., Givi, M. E., Nijkamp, F. P., & Folkerts, G. (2010). IL-8 production by macrophages is synergistically enhanced when cigarette smoke is combined with TNF-alpha. Biochemical Pharmacology, 79(5), 698-705.
Overige resultaten
Overbeek, S. A., Braber, S., Henricks, P. A. J., Kraneveld, A. D., Blalock, J. E., Nijkamp, F., & Folkerts, G. (2010). Exposure of human neutrophils to cigarette smoke or N-acetyl proline-glycine-proline results in CXCL8 and matrix metalloprotease 8 and 9 release.
Abdul Roda, M., Gaggar, A., Hardison, M. T., Blalock, J. E., Folkerts, G., & Jackson, P. L. (2010). Targeting prolyl endopeptidase with valproic acid as a potential modulator of chronic inflammation.
Bezemer, G. F. G., Mortaz, E., Den Brok, M., Van Ark, I., Kraneveld, A. D., Adema, G. J., Nijkamp, F., & Folkerts, G. (2010). Lps induced TNF-α production by bronchoaveolar lavage-and lung cells is increased in TLR 9 deficient mice.
Braber, S., Overbeek, S. A., Bezemer, G. F. G., Nijkamp, F., Henricks, P. A. J., Jackson, P. L., Blalock, J. E., Kraneveld, A. D., & Folkerts, G. (2010). Prolyl Endopeptidase (PE): An important enzyme involved in the development of lung emphysema?.
Braber, S., Overbeek, S. A., Bezemer, G. F. G., Henricks, P. A. J., Kraneveld, A. D., Folkerts, G., & Nijkamp, F. (2010). Smoking cessation reduces cytokine and chemokine levels but increases IL-10 in a mouse model for lung emphysema.
Morgan, M. E., Zheng, B., Folkerts, G., & Kraneveld, A. D. (2010). Following antigen-specific responses within dextran sodium sulfate colitis: Tools for drug research. 267.
Mortaz, E., Kraneveld, A., Nijkamp, F., & Folkerts, G. (2010). Cigarette smoke modulates release of CXCL8 through the inflammasome signaling in human bronchial epithelial cells (16HBE14o).
Mortaz, E., Ezzati Givi, N., Nijkamp, F., Kraneveld, A. D., & Folkerts, G. (2010). Modulation of CXCL-8 production through the inflammasome signaling by human bronchial epithelial cells (16HBE14O).
Overbeek, S. A., Braber, S., Henricks, P. A. J., Kraneveld, A. D., Nijkamp, F., & Folkerts, G. (2010). Human neutrophils stimulated with collagen breakdown product PGP results in chemotaxis, instant calcium influx and CXCL8 release.
2009
Wetenschappelijke publicaties
Braber, S., Hartog, A., Van Bergen-Henegouwen, J., Kraneveld, A. D., Folkerts, G., & Garssen, J. (2009). The role of collagen breakdown products inosteoarthritis. Naunyn-Schmiedeberg's Archives of Pharmacology, 379(2), 201. https://doi.org/10.1007/s00210-008-0340-5
Verheijden, K., Van Houwelingen, A. H., Van Ark, I., Nijkamp, F. P., & Folkerts, G. (2009). Cigarette smoke-induced lung emphysema: C57BL/6 versus BALB/c. Naunyn-Schmiedeberg's Archives of Pharmacology, 379(2), 213. https://doi.org/10.1007/s00210-008-0340-5
Henderik, R., Folkerts, G., & Hovius, J. W. R. (2009). Anticoagulante en immunosuppressieve eiwitten in tekenspeeksel: De teek als apo-teek van de toekomst. Pharmaceutisch Weekblad, 144(7), 24-27.
Mortaz, E., Lazar, Z., Koenderman, L., Kraneveld, A. D., Nijkamp, F. P., & Folkerts, G. (2009). Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of IL-8 in response to TLR-9 stimulation. Respiratory Research, 10, Article 47. https://doi.org/10.1186/1465-9921-10-47
Mortaz, E., Braber, S., Nazary, M., Givi, M. E., Nijkamp, F., & Folkerts, G. (2009). ATP in the pathogenesis of lung emphysema. European Journal of Pharmacology, 619(1-3), 92-96. https://doi.org/10.1016/j.ejphar.2009.07.022
Mortaz, E., Folkerts, G., Engels, G. M. H., Nijkamp, F. P., & Redegeld, F. A. M. (2009). Cigarette smoke suppresses in vitro allergic activation of mouse mast cells. Clinical and Experimental Allergy, 39(5), 679-687.
van Putte, B. P., Grootenboers, M. J. J. H., van Boven, W. J., Oosterhout, M., Pasterkamp, G., Folkerts, G., & Schramel, F. (2009). Selective pulmonary artery perfusion for the treatment of primary lung cancer: Improved drug exposure of the lung. Lung Cancer, 65, 208-213.
Grootenboers, M. J. J. H., Schramel, F. M., van Boven, W. J., Hendriks, J. M., van Schil, P. E., de Wit, P. E., Pasterkamp, G., Folkerts, G., & van Putte, B. P. (2009). Selective pulmonary artery perfusion followed by blood flow occlusion: new challenge for the treatment of pulmonary malignancies. Lung Cancer, 63, 400-404. http://www.ncbi.nlm.nih.gov/pubmed/18657338?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1
Mortaz, E., Kraneveld, A. D., Smit, J. J., Kool, M., Lambrecht, B. N., Kunkel, S. L., Lukacs, N. W., Nijkamp, F. P., & Folkerts, G. (2009). Effect of cigarette smoke extract on dendritic cells and their impact on T-cell proliferation. PLoS One, 4(3), 3. https://doi.org/10.1371/journal.pone.0004946
Calder, P. C., Albers, R., Antoine, J. M., Blum, S., Bourdet-Sicard, R., Ferns, G. A., Folkerts, G., Friedman, P. S., Frost, G. S., Guarner, F., Lovik, M., Macfarlane, S., Meyer, P. D., M'Rabet, L., Serafini, M., van Eden, W., van Loo, J., Vias Dias, W., Vidry, S., ... Zhao, J. (2009). Inflammatory disease processes and interactions with nutrition. British Journal of Nutrition, 101(Supple 1), 1-45.
Sarir, H., Mortaz, E., Karimi, K., Kraneveld, A. D., Rahman, I., Caldenhoven, E., Nijkamp, F. P., & Folkerts, G. (2009). Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages. Journal of Inflammation (BioMed Central), 6, Article 6:12. https://doi.org/10.1186/1476-9255-6-12
Mortaz, E., Lazar, Z., Koenderman, L., Kraneveld, A. D., Nijkamp, F. P., & Folkerts, G. (2009). Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of CXCL8 in response to TLR-9 stimulation. Respiratory Research, 10, 47.
Vakpublicaties
Henderik, R., Folkerts, G., & Hovius, J. W. R. (2009). Anticoagulant and immunosuppressive proteins in tick saliva: the tick as "apotheek" of the future. Pharmaceutisch Weekblad, 144(7), 24-27.
Overige resultaten
De Kruijf, P., Overbeek, S. A., Lim, H. D., Kraneveld, A., Folkerts, G., Leurs, R., & Smit, M. J. (2009). The collagen-breakdown product N-acetyl PGP does not interact directly with human CXCR1 and CXCR2. 268-269. Abstract from FIGON Dutch Medicins Days, Lunteren, Nederland. https://doi.org/10.1007/s00210-009-0422-z
Folkerts, G., Engels, F., Nijkamp, F., Redegeld, F., & Mortaz, E. (2009). Cigarette smoke differentially affects allergic activation of mast cells. 138. https://doi.org/10.1111/j.1398-9995.2009.02075.x
Mortaz, E., Ezzati Givi, M., Nijkamp, F. P., & Folkerts, G. (2009). Suppression of phosphoinositide 3-kinase signaling by cigarette smoke attenuates release of IFN-A by human plasmacytoid dendritic cells. 363. https://doi.org/10.1002/eji.200990184
Ezzati Givi, M., Mortaz, E., Nijkamp, F. P., & Folkerts, G. (2009). Effects of cigarette smoke on differentiation and maturation of mouse dendritic cells. Poster session presented at FIGON Dutch Medicines Day 2009, Lunteren, NL.
Kraneveld, A. D., Mortaz, E., Ito, K., Adcock, I., Nijkamp, F. P., Georgiou, N. A., & Folkerts, G. (2009). Cigarette smoke triggers human neutrophils to produce interleukin-8 via modulation of TLR9 receptor. Poster session presented at Keystone Symposium, Banff, Canada.
Overbeek, S. A., de Kruijf, P., Srienc, A., Lim, H., Henricks, P. A. J., Smit, M. J., Leurs, R., Kraneveld, A. D., & Folkerts, G. (2009). Involvement of CXCR2 in collagen breakdown product-induced chamotaxis of human neutrophils. Poster session presented at TiPharma Spring meeting, Utrecht, NL.
Folkerts, G., Engels, G. M. H., Nijkamp, F. P., Redegeld, F. A. M., & Mortaz, E. (2009). Cigarette smoke differentially affects allergic activation of mast cells. Poster session presented at EAACI, Warsaw, Poland.
Morgan, M. E., Zheng, B., Haazen, L., van Roest, M., Folkerts, G., & Kraneveld, A. D. (2009). Following antigen-specific responses within the Dextran Sodium Sulphate-induced colitis model. Poster session presented at NVVI, Noordwijkerhout, NL.
Braber, S., Nijkamp, F. P., Henricks, P. A. J., Blalock, J. E., Kraneveld, A. D., & Folkerts, G. (2009). Prolyl Endopeptidase (PE): an important enzyme involved in the development of lung emphysema?. Poster session presented at TiPharma Spring meeting, Utrecht, NL.
Zheng, B., Morgan, M. E., Folkerts, G., & Kraneveld, A. D. (2009). A survey of Toll-like receptors in the dextran sodium sulfate mouse model of colitis. Poster session presented at NVVI, Noordwijkerhout, NL.
Mortaz, E., Ezzati Givi, M., Bezemer, G. F. G., Nijkamp, F. P., Kraneveld, A. D., & Folkerts, G. (2009). Cigarette smoke extracts modulates CXCL-8 production in human bronchial epithelial (16HBE14o) cells by TLR signalling. Poster session presented at NVVI, Noordwijkerhout, NL.
2008
Wetenschappelijke publicaties
Sarir, H., Henricks, P. A. J., van Houwelingen, A. H., Nijkamp, F. P., & Folkerts, G. (2008). Cells, mediators and Toll-like receptors in COPD. European Journal of Pharmacology, 585(2-3), 346-353. https://doi.org/10.1016/j.ejphar.2008.03.009
Mortaz, E., Rad, M. V., Johnson, M., Raats, D., Nijkamp, F. P., & Folkerts, G. (2008). Salmeterol with fluticasone enhances the suppression of IL-8 release and increases the translocation of glucocorticoid receptor by human neutrophils stimulated with cigarette smoke. Journal of Molecular Medicine, 86(9), 1045-56. https://doi.org/10.1007/s00109-008-0360-0
van Putte, B. P., Grootenboers, M. J. J. H., van Boven, W. J., Hendriks, J. M. H., Schil, P. E. Y., Guetens, G., de Boeck, G., Pasterkamp, G., Schramel, F., & Folkerts, G. (2008). Pharmacokinetics of Gemcitabine when Delivered by Selective Pulmonary Artery Perfusion for the Treatment of Lung Cancer. Drug Metabolism and Disposition, 36, 676-681.
van Houwelingen, A. H., Weathington, N. M., Verweij, V. G. M., Blalock, J. E., Nijkamp, F. P., & Folkerts, G. (2008). Induction of lung emphysema is prevented by L-arginine-threonine-arginine. FASEB Journal, 22, 3403-3408.
Ricciardolo, F. L. M., Nijkamp, F. P., de Rose, V., & Folkerts, G. (2008). The guinea pig as an animal model for asthma. Current Drug Targets, 9, 452-465.
Folkerts, G., Kraneveld, A. D., & Nijkamp, F. P. (2008). New endogenous CXC chemokine ligands as potential targets in lung emphysema. Trends in Pharmacological Sciences, 29(4), 181-185.
Calder, P. C., Albers, R., Antoine, J.-M., Blum, S., Bourdet-Sicard, R., Ferns, G. A., Folkerts, G., Friedmann, P. S., Frost, G. S., Guarner, F., Lovik, M., Macfarlane, S., Meyer, P. D., M'Rabet, L., Serafini, M., van Eden, W., van Loo, J., vas Dias, W., Vidry, S., ... Zhao, J. (2008). Nutrition and inflammatory processes. In Proceedings of the Nutrition Society (pp. E9)
Mortaz, E., Redegeld, F. A. M., Sarir, H., Karimi, K., Raats, D. A. E., Nijkamp, F. P., & Folkerts, G. (2008). Cigarette smoke stimulates the production of chemokines in mast cells. Journal of Leukocyte Biology, 83(3), 575-580.
Vakpublicaties
Folkerts, G. (2008). COPD: Chronic Obstructive Pulmonary Diseases. Verbeterde vertaalslag van dier naar mens en vice versa. Conceptuur, 54, 10-12.
Overige resultaten
Overbeek, S. A., de Kruijf, P., Scrienc, A., Lim, H., Henricks, P. A. J., Smit, J. J., Leurs, R., Kraneveld, A. D., & Folkerts, G. (2008). Involvement of CXCR2 in collagen breakdown product-induced chemotaxis of human neutrophils. Poster session presented at FIGON Dutch Medicins Days, Lunteren, Nederland.
Hougee, S., Knippels, L. M. J., Nauta, A. J., Folkerts, G., Nijkamp, F. P., Knol, J., & Garssen, J. (2008). Oral treatment with a specific synbiotic mixture inhibits the allergic airway response in mice. Poster session presented at XXVII Congress of the European Academy of Allergology and Clinical Immunology, Barcelona, Spain.
Braber, S., Blokhuis, B. R. J., Redegeld, F. A. M., Kraneveld, A. D., & Folkerts, G. (2008). Free immunoglobulin light chains in COPD models. Poster session presented at FIGON Dutch Medicins Days, Lunteren, Nederland.
2007
Wetenschappelijke publicaties
Sarir, H., Mortaz, E., Karimi, K., Johnson, M., Nijkamp, F. P., & Folkerts, G. (2007). Combination of fluticasone propionate and salmeterol potentiates the suppression of cigarette smoke-induced IL-8 production by macrophages. European Journal of Pharmacology, 571(1), 55-61. https://doi.org/10.1016/j.ejphar.2007.05.034
Romagnoli, M., Caramori, G., Braccioni, F., Barreiro, E., Siafakas, N. M., Vignola, A. M., Chanez, P., Fabbri, L. M., Papi, A., Abraham, B., Anto, J. M., Bel, E. H. D., Bonsignore, G., Castellsague, J., Cibella, F., Cuttitta, G., Dahlen, B., Dahlen, S.-E., Drews, N., ... Yourgioti, G. (2007). Near-fatal asthma phenotype in the ENFUMOSA Cohort. Clinical and Experimental Allergy, 37, 552-557.
Vos, A. P., van Esch, B. C., Stahl, B., M'Rabet, L., Folkerts, G., Nijkamp, F. P., & Garssen, J. (2007). Dietary supplementation with specific oligosaccharide mixtures decreases parameters of allergic asthma in mice. International Immunopharmacology, 7(12), 1582-1587. https://doi.org/10.1016/j.intimp.2007.07.024
Ricciardolo, F. L. M., & Folkerts, G. (2007). Nitric oxide synthase as a therapeutic target in asthma. In R. Polosa, & S. T. Holgate (Eds.), Asthma: Modern Therapeutic Strategies (pp. 73-91). (Therapeutics Strategies). Atlas Medical Publishing Ltd.
Blasi, F., Aliberti, S., Allegra, L., Piatti, G., Tarsia, P., Ossewaarde, J. M., Verweij, V. G. M., Nijkamp, F. P., & Folkerts, G. (2007). Chlamydophila pneumoniae induces a sustained airway hyperresponsiveness and inflammation in mice. Respiratory Research, 8, 83.
Vakpublicaties
Ten Broeke, R., Deneer, V. H. M., Vernooij, P. D., Van Den Bosch, J. M. M., Folkerts, G., Tjoeng, M. M., Zanen, P., Van Der Zeijden, J., & Van Der Hoorn, Y. H. (2007). Het effect van bèta-agonisten en corticosteroïden op de cytokineproductie bij COPD-patiënten. Pharmaceutisch Weekblad, 142(11), 30-33.
ten Broeke, R., Deneer, V. H. M., Vernooij, P. D., van den Bosch, J. M. M., Folkerts, G., & Tjoeng, M. M. (2007). Het effect van beta-agonisten en corticosteroiden op de cytokineproductie bij COPD-patienten. PW Wetenschappelijk Platform, 1(2), 30-33.
van Roozendaal, B., & Folkerts, G. (2007). NO-NSIAD's. Pharmaceutisch Weekblad, 142, 20-21.
Overige resultaten
Mortaz, E., Sarir, H., Raats, D. A. E., Nijkamp, F. P., & Folkerts, G. (2007). Salmeterol and fluticasone by increasing translocation of glucocorticoid receptor inhibits releases of Il-8 induced cigarette smoke extract. Poster session presented at EAACI 2007, Gutenberg, Sweden.
Mortaz, E., Folkerts, G., Nijkamp, F. P., & Redegeld, F. A. M. (2007). Cigarette smoke suppresses the production of cytokines but nog chemeokines by IgE/Ag activation in mast cells. Poster session presented at World Allergy Meeting, Bangkok, Thailand.
Mortaz, E., Adcock, I., Kazuhiro, I., Nijkamp, F. P., & Folkerts, G. (2007). CPG potentiates the effects of cigarette smoke on releases of IL-8 in neutrophils. Poster session presented at Annual World Immunology Meeting 2007 (AAI), Miami, USA.
Sarir, H., Mortaz, E., Karimi, K., Nijkamp, F. P., & Folkerts, G. (2007). N-acetylcysteine prevents cigarette smoke (CS)-induced over expression of TLR4 on monocyte-derived macrophages (MDMs). Poster session presented at FIGON Medicines Days, Lunteren, Nederland.
Mortaz, E., Smit, J. J., Ketelaars, E., Raats, D. A. E., Kools, M., Nijkamp, F. P., & Folkerts, G. (2007). Effects of cigarette smoke extracts on immunologic function of plasmacytoid dendritic cells. Poster session presented at American thoracic Society, San Francisco, USA.
Overbeek, S. A., Mortaz, E., Nijkamp, F. P., & Folkerts, G. (2007). Human nutrophiles from smokers vs. non-smokers produce more MMP's elastase and IL-8 after stimulation with cigarette smoke. Poster session presented at FIGON Medicines Days 2007, Lunteren, Nederland.
Vaezirad, M. M., Mortaz, E., Kraneveld, A. D., Nijkamp, F. P., & Folkerts, G. (2007). Salmeterol and Fluticason by increasing of translocation of glucocorticoid receptors suppress cigarette smoke-induced IL-8 production by neutrophils. Poster session presented at FIGON Medicines Days 2007, Lunteren, Nederland.
Mortaz, E., Raats, D. A. E., Vader, P., Adcock, I., Ito, K., Nijkamp, F. P., & Folkerts, G. (2007). CPG potentiates the effects of cigarette smoke on releases of IL-8 in neutrophils. Poster session presented at FIGON Medicines Days 2007, Lunteren, Nederland.
Braber, S., den Hartog, A., van Bergenhenegouwen, B. J., Kraneveld, A. D., Folkerts, G., & Garssen, J. (2007). The role of collagen breakdown products in osteoarthritis. Poster session presented at FIGON Medicines Days 2007, Lunteren, Nederland.
2006
Wetenschappelijke publicaties
Folkerts, G., & Groneberg, D. A. (2006). European Journal of Pharmacology: Preface. European Journal of Pharmacology, 533(1-3), 1. https://doi.org/10.1016/j.ejphar.2006.01.012
Weathington, N. M., Van Houwelingen, A. H., Noerager, B. D., Jackson, P. L., Kraneveld, A. D., Galin, F. S., Folkerts, G., Nijkamp, F. P., & Blalock, J. E. (2006). Weathington et al. reply [2]. Nature Medicine, 12(6), 604. https://doi.org/10.1038/nm0606-604
Karimi, K., Sarir, H., Mortaz, E., Smit, J. J., Hosseini, H., de Kimpe, J. J., Nijkamp, F. P., & Folkerts, G. (2006). Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages. Respiratory Research, 7, 66-66.
ten Broeke, R., de Crom, R., van Haperen, R., Verweij, V. G. M., Leusink-Muis, A., van Ark, I., de Clerck, F., Nijkamp, F. P., & Folkerts, G. (2006). Overexpression of endothelial nitric oxide synthase suppresses features of allergic asthma in mice. Respiratory Research, 7.
Folkerts, G., & Nijkamp, F. P. (2006). Nitric oxide in asthma therapy. Current Pharmaceutical Design, 12, 3221-3232.
Ricciardolo, F. L. M., Di Stefano, A., Sabatini, F., & Folkerts, G. (2006). Reactive nitrogen species in the respiratory tract. European Journal of Pharmacology, 533, 8-18.
Ricciardolo, F. L. M., Nijkamp, F. P., & Folkerts, G. (2006). Nitric oxide synthase (NOS) as therapeutic target for asthma and chronic obstructive pulmonary disease. Current Drug Targets, 7, 721-735.
Weathington, N. M., van Houwelingen, A. H., Noerager, B. D., Jackson, P. L., Kraneveld, A. D., Galin, F. S., Folkerts, G., Nijkamp, F. P., & Blalock, J. E. (2006). A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation. Nature Medicine, 12(3), 317-323. https://doi.org/10.1038/nm1361
van Putte, B. P., Hendriks, J. M. H., Guetens, G., de Boeck, G., de Bruijn, E. A., Schil, P. E. Y., & Folkerts, G. (2006). Modified approach of administering cytostatics to the lung: more efficient isolated lung perfusion. Annals of Thoracic Surgery, 82, 1033-1037.
Overige resultaten
Mortaz, E., Sarir, H., Yosefi, S., Agar, C., Hussaini, K., Nijkamp, F. P., & Folkerts, G. (2006). Cigarette smoke media increases production of IL-8 and ENA-78 by human neutrophil's. Poster session presented at FOCIS, San Francisco, USA.
Sarir, H., Mortaz, E., Nijkamp, F. P., & Folkerts, G. (2006). Cigarette smoke induces chemokine releases and suppresses degranulation of bone marrow drived mast cells. Poster session presented at 1st Joint Meeting of European National Societies of Immunology - 16th European Congress of Immunology, Paris, France.
Mortaz, E., Sarir, H., Yosefi, S., Agar, C., Hussaini, K., Nijkamp, F. P., & Folkerts, G. (2006). Cigarette smoke media induces MIP-1alpha release from mast cells. Poster session presented at EACCI, Vienna, Austria.
Mortaz, E., Sarir, H., Yosefi, S., Agar, C., Hussaini, K., Nijkamp, F. P., & Folkerts, G. (2006). effects of cigarette smoke on proteases and elastase release of human neutrophils. Poster session presented at American thoracic Society, San Diego, USA.
2005
Wetenschappelijke publicaties
van Putte, B. P., Huisman, A., Hendriks, J. M., van Schil, P. E., van Boven, W. J., Schramel, F. M., Nijkamp, F. P., & Folkerts, G. (2005). Pulmonary intravascular volume can be used for dose calculation in isolated lung perfusion. European Journal of Cardio-thoracic Surgery, 28(4), 594-598.
https://dspace.library.uu.nl/bitstream/handle/1874/11612/folkerts_05_pulmonary_intravascular.pdf?sequence=2
https://dspace.library.uu.nl/bitstream/handle/1874/11612/folkerts_05_pulmonary_intravascular.pdf?sequence=2
Gaga, M., Papageorgiou, N., Yiourgioti, G., Karydi, P., Liapikou, A., Bitsakou, H., Zervas, E., Koulouris, N. G., Holgate, S. T., Abraham, B., Anto, J. M., Barreiro, E., Bel, E. H. D., Bonsignore, G., Bousquet, J., Castellsague, J., Chanez, P., Cibella, F., Cuttita, G., ... Watson, L. (2005). Risk factors and characteristics associated with severe and difficult to treat asthma phenotype: an analysis of the ENFUMOSA group of patients based on the ECRHS questionnaire. Clinical and Experimental Allergy, 35, 954-959.
2004
Wetenschappelijke publicaties
Folkerts, G., & Nijkamp, F. P. (2004). Airway nitrergic pathways: is there therapeutic potential in asthma and COPD? Current Opinion in Pharmacology, 4(3), 202-206. https://doi.org/10.1016/j.coph.2004.01.005
Smit, J. J., Folkerts, G., & Nijkamp, F. P. (2004). Ramp-ing up allergies: Nramp1 (Slc11a1), macrophages and the hygiene hypothesis. Trends in Immunology, 25, 342-347.
https://dspace.library.uu.nl/bitstream/handle/1874/14961/folkerts_04_ramping_up_allergies.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/14961/folkerts_04_ramping_up_allergies.pdf?sequence=1
Ricciardolo, F. L. M., Sterk, P. J., Gaston, B., & Folkerts, G. (2004). Nitric oxide in health and disease of the respiratory system. Physiological Reviews, 84, 731-765.
https://dspace.library.uu.nl/bitstream/handle/1874/14963/folkerts_04_nitric_oxidenr2.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/14963/folkerts_04_nitric_oxidenr2.pdf?sequence=1
ten Broeke, R., Leusink-Muis, A., Hilberdink, R., van Ark, I., van den Worm, E., Villain, M., de Clerck, F., Blalock, J. E., Nijkamp, F. P., & Folkerts, G. (2004). Specific modulation of calmodulin activity induces a dramatic production of superoxide by alveolar macrophages. Laboratory Investigation, 84, 29-40.
https://dspace.library.uu.nl/bitstream/handle/1874/14957/folkerts_04_specific_modulation.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/14957/folkerts_04_specific_modulation.pdf?sequence=1
Smit, J. J., Folkerts, G., & Nijkamp, F. P. (2004). Mycobacteria, genes and the 'hygiene hypothesis'. Current Opinion in Allergy and Clinical Immunology, 4, 57-62.
https://dspace.library.uu.nl/bitstream/handle/1874/14956/folkerts_04_mycobacteria.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/14956/folkerts_04_mycobacteria.pdf?sequence=1
ten Broeke, R., Blalock, J. E., Nijkamp, F. P., & Folkerts, G. (2004). Calcium sensors as new therapeutic targets for asthma and chronic obstructive pulmonary disease. Clinical and Experimental Allergy, 34, 170-176.
Groneberg, D. A., Folkerts, G., Peiser, C., Chung, K. F., & Fischer, A. (2004). Neuropeptide Y (NPY). Pulmonary Pharmacology & Therapeutics, 17(4), 173-180. https://doi.org/10.1016/j.pupt.2004.04.003
Henricks, P. A. J., Folkerts, G., & Nijkamp, F. P. (2004). Asthma and oxidative stress. In V. Vallyathan, V. Castranova, & X. Shi (Eds.), Oxygen/Nitrogen Radicals. Lung Injury and Disease (pp. 413-444). (Lung Biology in Health and Diseases; No. 187). Marcel Dekker.
Vakpublicaties
Ten Broeke, R., & Folkerts, G. (2004). De (patho)fysiologie van stikstofoxide in de luchtwegen. Pharmaceutisch Weekblad, 139(44), 1458-1461.
ten Broeke, R., & Folkerts, G. (2004). Ingespannen zoeken naar ontspanning. Pharmaceutisch Weekblad, 139, 1458-1461.
2003
Wetenschappelijke publicaties
Abraham, B., Antó, J. M., Barreiro, E., Bel, E. H. D., Bonsignore, G., Bousquet, J., Castellsague, J., Chanez, P., Cibella, F., Cuttitta, G., Dahlén, B., Dahlén, S.-E., Drews, N., Djukanovic, R., Fabbri, L. M., Folkerts, G., Gaga, M., Gratziou, C., Guerrera, G., ... Yourgioti, G. (2003). The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma. European Respiratory Journal, 22(3), 470-477. https://doi.org/10.1183/09031936.03.00261903
Smit, J. J., van Loveren, H., Hoekstra, M. O., van der Kant, P. A. A., Folkerts, G., & Nijkamp, F. P. (2003). Therapeutic treatment with heat-killed Mycobacterium vaccae (SRL172) in a mild and severe mouse model for allergic asthma. European Journal of Pharmacology, 470, 193-199.
Muijsers, R. B. R., Nijkamp, F. P., & Folkerts, G. (2003). Nitric oxide and other inflammatory mediators. In S. L. Johnston, & N. G. Papadopoulos (Eds.), Respiratory infections in allergy and asthma (pp. 229-250). Marcel Dekker.
Smit, J. J., van Loveren, H., Hoekstra, M. O., Schijf, M. A., Folkerts, G., & Nijkamp, F. P. (2003). Mycobacterium vaccae administration during allergen sensitization or challenge suppresses asthmatic features. Clinical and Experimental Allergy, 33, 1083-1089.
ten Broeke, R., Brandhorst, M. C., Leusink-Muis, A., Villain, M., de Clerck, F., Blalock, J. E., Nijkamp, F. P., & Folkerts, G. (2003). Ca2+ sensors modulate asthmatic symptoms in an allergic model for asthma. European Journal of Pharmacology, 476, 151-157.
Ricciardolo, F. L. M., Timmers, M. C., Sont, J. K., Folkerts, G., & Sterk, P. J. (2003). Effect of bradykinin on allergen induced increase in exhaled nitric oxide in asthma. Thorax, 58, 840-845.
Smit, J. J., van Loveren, H., Hoekstra, M. O., Folkerts, G., & Nijkamp, F. P. (2003). Prophylactic treatment with heat-killed M. vaccae (SRL172) in a mouse model for allergic asthma. In G. Marone (Ed.), Clinical Immunology and Allergy in Medicine (pp. 385-396). JGC Editions.
Abraham, B., Anto, J. M., Barreiro, E., Bel, E. H. D., Bonsignore, G., Bousquet, J., Castellsague, J., Chanez, P., Cibella, F., Cuttitta, G., Dahlen, B., Dahlen, S.-E., Drews, N., Djukanovic, R., Fabbri, L. M., Folkerts, G., Gaga, M., Gratziou, C., Holgate, S. T., ... Yourgioti, G. (2003). The ENFUMOSA cross-sectional European multicentre study of the cinical phenotype of chronic severe asthma. European Respiratory Journal, 22, 470-477.
Smit, J. J., van Loveren, H., Hoekstra, M. O., Karimi, K., Folkerts, G., & Nijkamp, F. P. (2003). The Slc11a1 (Nramp1) gene controls efficacy of mycobacterial treatment of allergic asthma. Journal of Immunology, 171, 754-760.
Kloek, J., van Ark, I., de Clerck, F., Bloksma, M. A., Nijkamp, F. P., & Folkerts, G. (2003). Modulation of airway hyperresponsiveness by thiols in a murine in vivo model of allergic asthma. Inflammation Research, 52, 126-131.
2002
Wetenschappelijke publicaties
Muijsers, R. B. R., Van Der Veeken, A., Habernickel, J., Folkerts, G., Postma, D. S., & Nijkamp, F. P. (2002). Intra-luminal exposure of murine airways to peroxynitrite causes inflammation but not hyperresponsiveness. Inflammation Research, 51(1), 33-37.
Kloek, J., van Ark, I., Bloksma, N., De Clerck, F., Nijkamp, F. P., & Folkerts, G. (2002). Glutathione and other low-molecular-weight thiols relax guinea pig trachea ex vivo: interactions with nitric oxide? American journal of physiology. Lung cellular and molecular physiology, 283(2), L403-408. https://doi.org/10.1152/ajplung.00376.2001
Scheerens, J., van Gessel, S. B. E., Nijkamp, F. P., & Folkerts, G. (2002). Eotaxin protein levels and airway pathology in a mouse model for allergic asthma. European Journal of Pharmacology, 453(1), 111-7.
Fischer, K., Folkerts, G., Geppetti, P., & Groneberg, D. A. (2002). Mediators of asthma: nitric oxide. Pulmonary Pharmacology & Therapeutics, 15, 73-81.
Sadeghi - Hashjin, G., Nijkamp, F. P., Henricks, P. A. J., & Folkerts, G. (2002). Sodium cromoglycate and doxantrazole are oxygen radical scavengers. European Respiratory Journal, 20, 867-872.
Haag, M., Leusink-Muis, A., le Bouquin, R., Nijkamp, F. P., Lugnier, A., Frossard, N., Folkerts, G., & Pons, F. (2002). Increased expression and decreased activity of cytochrome P450 1A1 in a murine model of toluene diisocyanate-induced asthma. Archives of Toxicology, 76, 621-627.
Kloek, J., Nijkamp, F. P., Bloksma, M. A., de Clerck, F., & Folkerts, G. (2002). Differential responsiveness of proximal and distal parts of isolated guinea pig trachea. European Journal of Pharmacology, 442, 289-294.
Scheerens, J., van Gessel, S. B. E., Nijkamp, F. P., & Folkerts, G. (2002). Eotaxin protein level and airway pathology in a mouse model for allergic asthma. European Journal of Pharmacology, 453, 111-117.
2001
Wetenschappelijke publicaties
Muijsers, R. B. R., Ten Hacken, N. H. T., Van Ark, I., Folkerts, G., Nijkamp, F. P., & Postma, D. S. (2001). L-arginine is not the limiting factor for nitric oxide synthesis by human alveolar macrophages in vitro. European Respiratory Journal, 18(4), 667-671. https://doi.org/10.1183/09031936.01.00101301
Folkerts, G., van Heuven-Nolsen, D., & Nijkamp, F. P. (2001). Bradykinin causes inhibition of methacholine-induced bronchoconstriction in vivo in mice. Naunyn-Schmiedeberg's Archives of Pharmacology, 364(1), 53-58. https://doi.org/10.1007/s002100100430
Muijsers, R. B. R., van Ark, I., Folkerts, G., Koster, A. S., van Oosterhout, A. J. M., Postma, D. S., & Nijkamp, F. P. (2001). Apocynin and 1400 W prevents airway hyperresponsiveness during allergic reactions in mice. British Journal of Pharmacology, 134, 434-440.
Folkerts, G., Kloek, J., Geppetti, P., van der Linde, H. J., & Nijkamp, F. P. (2001). Factors that determine acetylcholine responsiveness of guinea pig tracheal tubes. European Journal of Pharmacology, 420, 151-157.
Folkerts, G., Kloek, J., Muijsers, R. B. R., & Nijkamp, F. P. (2001). Reactive nitrogen and oxygen species in airway inflammation. European Journal of Pharmacology, 429, 251-262.
ten Broeke, R., Folkerts, G., Leusink-Muis, A., van der Linde, H. J., Villain, M., Manion, M., de Clerck, F., Blalock, J. E., & Nijkamp, F. P. (2001). Calcium sensors as new therapeutic targets for airway hyperresponsiveness and asthma. FASEB Journal, 15, 1831-1833.
Folkerts, G., van Heuven-Nolsen, D., & Nijkamp, F. P. (2001). Bradykinin causes inhibition of methacholine-induced bronchoconstriction in vivo in mice. Naunyn-Schmiedeberg's Archives of Pharmacology, 364, 53-58.
Folkerts, G., van der Linde, H. J., & Nijkamp, F. P. (2001). Overview of experimental animal respiratory viral provocation models. In D. P. Skoner (Ed.), Asthma and respiratory infections; Lung biology in health and disease Vol. 154 (pp. 129-154). Marcel Dekker.
Overige resultaten
Scheerens, J., Stirling, R. G., Barnes, P. J., Folkerts, G., & Chung, K. F. (2001). Eotaxin inhalation results in increasing numbers of sputum eosinophils in mild asthmatic volunteers. A196-A196. Abstract from Unknown event, Asilomar, USA.
Kloek, J., Folkerts, G., Bloksma, M. A., Lilly, C. M., de Clerck, F., Drazen, J. M., & Nijkamp, F. P. (2001). Glutathione modulates non-specific and allergen-induced airway responsiveness in the guinea pig. A925-A925. Abstract from Unknown event, Asilomar, USA.
2000
Wetenschappelijke publicaties
Tognetto, M., Schmidlin, F., Trevisani, M., Nijkamp, F. P., Gies, J.-P., Frossard, N., Amadesi, S., Folkerts, G., & Geppetti, P. (2000). Expression of B1receptor in the mouse trachea. European Respiratory Review, 10(73), 267-268.
Rook, G. A. W., Folkerts, G., Walzl, G., & Openshaw, P. (2000). Clean living increases more than just atopic disease (multiple letters) [1]. Immunology Today, 21(5), 249-250.
Nijkamp, F. P., & Folkerts, G. (2000). Nitric oxide and bronchial hyperresponsiveness. In M. G. Belvisi, & J. A. Mitchell (Eds.), Nitric oxide in pulmonary processes: role in physiology and pathophysiology of lung disease (pp. 111-126). Birkhaüser.
Folkerts, G., Westra-de Vlieger, J., De Vries, A., Faas, S., Van Der Linde, H., Engels, F., De Jong, J. C., Verheyen, F. A. K. C. P., Van Heuven-Nolsen, D., & Nijkamp, F. P. (2000). Virus- and bradykinin-induced airway hyperresponsiveness in guinea pigs. American Journal of Respiratory and Critical Care Medicine, 161(5), 1666-1671.
Hjoberg, J., Folkerts, G., van Gessel, S. B. E., Hogman, M., Hedenstierna, G., & Nijkamp, F. P. (2000). Hyperosmolarity-induced relaxation and prostaglandin release in guinea pig trachea in vitro. European Journal of Pharmacology, 398, 303-307.
Folkerts, G., ten Broeke, R., Fischer, K., Geppetti, P., & Nijkamp, F. P. (2000). Nitric oxide control of airway smooth muscle. European Respiratory Review, 10(73), 249-252.
Folkerts, G., Fischer, K., Muijsers, R. B. R., & Nijkamp, F. P. (2000). Peroxynitrite and nitrergic neural transmission: pathophysiological implications. In S. Kalsner (Ed.), Nitric oxide and free radicals in peripheral neurotransmission (pp. 279-306). (Nitric oxide in biology and medicine; No. 2). Birkhaüser.
Muijsers, R. B. R., van den Worm, E., Folkerts, G., Beukelman, C. J., Koster, A. S., Postma, D. S., & Nijkamp, F. P. (2000). Apocynin inhibits peroxynitrite formation by murine macrophages. British Journal of Pharmacology, 130, 932-936.
Tognetto, M., Schmidlin, F., Trevisani, M., Nijkamp, F. P., Gies, J. P., Frossard, N., Amadesi, S., Folkerts, G., & Geppetti, P. (2000). Expression of B1 receptor in the mouse trachea. European Respiratory Review, 10(73), 267-268.
Folkerts, G., & Nijkamp, F. P. (2000). Epithelial control over smooth-muscle responsiveness. In W. W. Busse, & S. T. Holgate (Eds.), Asthma and Rhinitis Vol. 2 (pp. 1425-1433). Blackwell.
Folkerts, G., Walzl, G., & Openshaw, P. J. M. (2000). Do common childhood infections 'teach' the immune system not to be allergic? Immunology Today, 21, 118-120.
Vakpublicaties
Folkerts, G., Walzl, G., & Openshaw, P. (2000). Reply to Rook. Immunology Today, 21, 249-250.
Overige resultaten
Smit, J. J., Folkerts, G., Leusink-Muis, A., Sandvold, M. L., Myhren, F., & Nijkamp, F. P. (2000). A derivative of methylprednisolone, P4114, is more potent in suppressing the ovalbumin-induced bronchoconstriction in guinea pigs. 248-248. Abstract from Unknown event, Asilomar, USA.
Scheerens, J., van Gessel, S. B. E., Folkerts, G., Sterk, P., Hiemstra, P., & Nijkamp, F. P. (2000). The increase in eotaxin concentration in the airways of ovalbumin sensitised and challenged mice is not related to the development of airway eosinophilia of airway hyperresponsiveness. A383-A838. Abstract from Unknown event, Asilomar, USA.
Kloek, J., Folkerts, G., Bloksma, M. A., de Clerck, F., & Nijkamp, F. P. (2000). Relaxing effects of glutathione and other thiols in guinea-pig trachea Ex Vivo: interactions with nitric oxide. A743-A743. Abstract from Unknown event, Asilomar, USA.
ten Broeke, R., Folkerts, G., Leusink-Muis, A., Manion, M., Villain, M., de Clerck, F., Blalock, J. E., & Nijkamp, F. P. (2000). Complementary peptides to EF hand of calmodulin modulate airway responsiveness and [Ca2+]1 and nitric oxide production by guinea pig tracheal epithelial cells. 46-46. Abstract from Unknown event, Asilomar, USA.
Muijsers, R. B. R., van Ark, I., Folkerts, G., van Oosterhout, A. J. M., Koster, A. S., Postma, D. S., & Nijkamp, F. P. (2000). Inhibitors of both NADPH-oxidase and nitric oxide synthase prevent airway hyperresponsiveness but not allergic inflammation in a murine model of asthma. 54-54. Abstract from Unknown event, Asilomar, USA.
Folkerts, G., Leusink-Muis, A., Sandvold, M. L., Myhren, F., & Nijkamp, F. P. (2000). The acute allergen-induced bronchoconstriction in guinea pigs is prevented by aerosols with P4114, a derivative of methylpredisolone (MP). 559s. Abstract from Unknown event, Asilomar, USA.
1999
Wetenschappelijke publicaties
Folkerts, G., & Nijkamp, F. (1999). Folkerts and Nijkamp reply. Trends in Pharmacological Sciences, 20(2), 53-54.
Scheerens, J., Folkerts, G., Van Der Linde, H., Sterk, P. J., Conroy, D. M., Williams, T. J., & Nijkamp, F. P. (1999). Eotaxin levels and eosinophils in guinea pig broncho-alveolar lavage fluid are increased at the onset of a viral respiratory infection. Clinical and Experimental Allergy, 29 Suppl 2, 74-77.
Leusink-Muis, A., Folkerts, G., Sandvold, M. L., Myhren, F., & Nijkamp, F. P. (1999). P4112 and P4114, derivatives of betamethasone and methylprednisolone, respectively, are more potent in reducing rat peritoneal cell numbers and activity. In H. E. Neffen, & C. E. Baena-Cagnani (Eds.), VXI World congress of Asthma (pp. 23-26). Monduzzi editore S.p.A..
Leusink-Muis, A., ten Broeke, R., Folkerts, G., de Clerck, F., & Nijkamp, F. P. (1999). Betametasone prevents virus-induced airway inflammation but not airway hyperresponsiveness in guinea pigs. Clinical and Experimental Allergy, 29(suppl. 2), 82-85.
Trevisani, M., Schmidlin, F., Tognetto, M., Nijkamp, F. P., Gies, J. P., Frossard, N., Amadesi, S., Folkerts, G., & Geppetti, P. (1999). Evidence for in vitro expression of B1 receptor in the mouse trachea and urinary bladder. British Journal of Pharmacology, 126, 1293-1300.
Hammermann, R., Hirschmann, J., Hey, C., Mossner, J., Folkerts, G., Nijkamp, F. P., Wessler, I., & Racke, K. (1999). Cationic proteins inhibit L-arginine uptake in rat alveolar macrophages and tracheal epithelial cells. Implications for nitric oxide synthesis. American Journal of Respiratory and Critical Care Medicine, 21, 155-162.
Nijkamp, F. P., & Folkerts, G. (1999). Nitric oxide and bronchial hyperresponsiveness. In M. G. Belvisi, & J. A. Mitchell (Eds.), Nitric oxide in pulmonary processes: role in physiology and pathophysiology of lung disease (pp. 111-126). Birhauser Verlag.
Vakpublicaties
Folkerts, G., & Nijkamp, F. P. (1999). Reply: airway epithelium: more than just a source for epithelium-derived relaxing factors! Trends in Pharmacological Sciences, 20, 53-54.
ten Hacken, N. H., Timens, W., van der Mark, T., Nijkamp, F. P., Postma, D. S., & Folkerts, G. (1999). Stikstofmonoxide en astma. Nederlands Tijdschrift voor Geneeskunde, 143, 1606-1611.
Overige resultaten
Leusink-Muis, A., Broeke, R. T., Folkerts, G., De Clerck, F., & Nijkamp, F. P. (1999). Betamethasone prevents virus-induced airway inflammation but not airway hyperresponsiveness in guinea pigs. 82-85.
Kloek, J., Folkerts, G., de Clerck, F., & Nijkamp, F. P. (1999). Glutathione and other thiols relax guinea-pig trachea ex vivo and enhance NO-concentrations in the tracheal effluent. 15-15. Abstract from Unknown event, Asilomar, USA.
Folkerts, G., Leusink-Muis, A., ten Broeke, R., de Clerck, F., & Nijkamp, F. P. (1999). Potential links between virus-induced and allergen-induced airway inflammation and airway hyperresponsiveness in animal models. 1-2. Abstract from Unknown event, Asilomar, USA.
Kloek, J., Folkerts, G., de Clerck, F., & Nijkamp, F. P. (1999). Thiols relax guinea-pig trachea via K+-channels, not via activation of guanylate cyclase. 133-133. Abstract from Unknown event, Asilomar, USA.
Hjoberg, J., Folkerts, G., Hogman, M., Hedenstierna, G., & Nijkamp, F. P. (1999). Prostaglandins are responsible for the hyperosmolarity induced relaxations of the guinea pig trachea. A396-A396. Abstract from Unknown event, Asilomar, USA.
Folkerts, G. (1999). Potential links between virus-induced and allergen-induced airway inflammation and airway hyperresponsiveness in animal models. 5-5. Abstract from Unknown event, Asilomar, USA.
Leusink-Muis, A., Folkerts, G., Sandvold, M. L., Myhren, F., & Nijkamp, F. P. (1999). P4112 and P4114, derivates of betamethasone and methulprednisolone, respectively, are more potent in reducing rat peritoneal cell numbers and activity. 134-134. Abstract from Unknown event, Asilomar, USA.
Scheerens, J., Folkerts, G., van der Linde, H. J., Conroy, D. M., Sterk, P., Williams, T. J., & Nijkamp, F. P. (1999). Increased eotaxin levels in BAL fluid of guinea pigs infected with a respiratory virus. 138-138. Abstract from Unknown event, Asilomar, USA.
Kloek, J., Folkerts, G., de Clerck, F., & Nijkamp, F. P. (1999). Glutathione reduces guinea-pig tracheal hyperreactivity caused by epithelial denudation in a perfused organ bath. A410-A410. Abstract from Unknown event, Asilomar, USA.
ten Broeke, R., Folkerts, G., van der Linde, H. J., Leusink-Muis, A., Blalock, J. E., de Clerck, F., & Nijkamp, F. P. (1999). In vitro effects of the EF hand-binding peptides CALP1 and CALP2 on guinea pig tracheal tubes. 126-126. Abstract from Unknown event, Asilomar, USA.
Muijsers, R. B. R., van Ark, I., Folkerts, G., Postma, D. S., & Nijkamp, F. P. (1999). Inhibition of peroxynitrite formation prevents allergen-induced hyperresponsiveness in a murine model of allergic asthma. 41-41. Abstract from Unknown event, Asilomar, USA.
ten Broeke, R., Folkerts, G., van der Linde, H. J., Leusink-Muis, A., Blalock, J. E., de Clerck, F., & Nijkamp, F. P. (1999). Modulation of guinea pig tracheal responsiveness by EF hand-binding calcium-like peptides CALP-1 and CALP-2. A398-A398. Abstract from Unknown event, Asilomar, USA.
van den Worm, E., Muijsers, R. B. R., Folkerts, G., Beukelman, C. J., van den Berg, A. J. J., Kroes, B. H., van Dijk, H., Labadie, R. P., & Nijkamp, F. P. (1999). Apocynin inhibits peroxynitrite formation by J774 macrophages. Abstract from Joint meeting of: American Society of Pharmacognosy, Amsterdam.
Muijsers, R. B. R., Folkerts, G., Habernickel, J., Postma, D. S., & Nijkamp, F. P. (1999). Peroxynitrite induced airway-hyperresponsiveness in the mouse. A884-A884. Abstract from Unknown event, Asilomar, USA.
1998
Wetenschappelijke publicaties
Kraneveld, A. D., Folkerts, G., Van Oosterhout, A. J., & Nijkamp, F. P. (1998). Airway hyperresponsiveness: first eosinophils and then neuropeptides. International Journal of Immunopharmacology, 19(9-10), 517-27.
Folkerts, G., Busse, W. W., Nijkamp, F. P., Sorkness, R., & Gern, J. E. (1998). Virus-induced airway hyperresponsiveness and asthma. American Journal of Respiratory and Critical Care Medicine, 157(6 Pt 1), 1708-1720. https://doi.org/10.1164/ajrccm.157.6.9707163
Sadeghi-Hashjin, G., Henricks, P. A., Folkerts, G., Muis, T., Garssen, J., & Nijkamp, F. P. (1998). Role of the epithelial layer in the generation of superoxide anion by the guinea-pig isolated trachea. Mediators of Inflammation, 7(1), 35-40. https://doi.org/10.1080/09629359891360
Sadeghi-Hashjin, G., Folkerts, G., Henricks, P. A., Muijsers, R. B., & Nijkamp, F. P. (1998). Peroxynitrite in airway diseases. Clinical and Experimental Allergy, 28(12), 1464-73.
Folkerts, G., & Nijkamp, F. P. (1998). Airway epithelium: more than just a barrier! Trends in Pharmacological Sciences, 19, 334-341.
Emanueli, C., Riccardolo, F., Vergnani, L., Bertrand, C., Ricci, F., Manzoli, N., Folkerts, G., Nijkamp, F. P., & Geppetti, P. (1998). Characterization of the endothelin receptor mediating epithelium-derived relaxant nitric oxide release form guinea-pig trachea. British Journal of Pharmacology, 125, 963-968.
Sadeghi - Hashjin, G., Folkerts, G., Henricks, P. A. J., & Nijkamp, F. P. (1998). Peroxynitrite in airway disease. Clinical and Experimental Allergy, 28, 1464-1473.
Muijsers, R. B. R., Folkerts, G., van den Worm, E., Beukelman, C. J., Postma, D. S., & Nijkamp, F. P. (1998). Inhibition of peroxynitrite formation by apocynin in a murine macrophage cell-line. British Journal of Pharmacology, 123, 112-112.
Folkerts, G., & Nijkamp, F. P. (1998). Viral infection and asthma; the modulatory role of nitric oxide on prostaglandin H synthase. In A. Szczeklik, R. Gryglewski, & J. R. Vane (Eds.), Eicosanoids, Asprin, and Asthma (pp. 231-251). Marcel Dekker.
Folkerts, G., Kraneveld, A. D., van Oosterhout, A. J. M., & Nijkamp, F. P. (1998). Mast cells, eosinophils and NANC-nerves in viral respiratory tract infections. European Respiratory Review, 64, 1111-1121.
Vakpublicaties
Gerritsen, J., & Folkerts, G. (1998). Symposium Bronchitus VI Groningen. Pulmonair, 6, 2-8.
Folkerts, G. (1998). The biology of nitric oxide. Pulmonair, 5, 2-4.
Overige resultaten
Hammermann, R., Hirschmann, J., Folkerts, G., Nijkamp, F. P., Wessler, I., & Racke, K. (1998). Differential effects of poly-cationic peptides on L-arginine utilization by NO synthase and arginase in rat alveolar macrophages (AM). 42P-42P. Abstract from Unknown event, Asilomar, USA.
Folkerts, G., van der Linde, H. J., & Nijkamp, F. P. (1998). Nitric oxide and cholinesterase suppresses the acetylcholine induced contractions in guinea pig airways. A37-A37. Abstract from Unknown event, Asilomar, USA.
Muijsers, R. B. R., Folkerts, G., van den Worm, E., Beukelman, C. J., Postma, D. S., & Nijkamp, F. P. (1998). Inhibition of peroxynitrite formation by apocynin in a murine macrophage cell-line. 112-112. Abstract from Unknown event, Asilomar, USA.
Muijsers, R. B. R., Folkerts, G., van den Worm, E., Beukelman, C. J., Postma, D. S., & Nijkamp, F. P. (1998). Inhibition of peroxynitrite formation in the murine macrophage cell-line. A234-A234. Abstract from Unknown event, Asilomar, USA.
van Heuven-Nolsen, D., van Velsen, D., Folkerts, G., & Nijkamp, F. P. (1998). Bradykinin causes inhibition of the methacholine-induced bronchoconstriction. A80-A80. Abstract from Unknown event, Asilomar, USA.
van Heuven-Nolsen, D., van Velsen, D., Folkerts, G., & Nijkamp, F. P. (1998). Bradykinin causes inhibition of methacholine-induced bronchoconstriction in vivo in mice.. 159P-159P. Abstract from Unknown event, Asilomar, USA.
Hammermann, R., Hirschmann, J., Hey, C., Folkerts, G., Nijkamp, F. P., Gleich, G. J., Wessler, I., & Racke, K. (1998). Polycationic peptides inhibit L-arginine (L-Arg) transport in rat and guinea-pig alveolar macrophages (AM). R327-R327. Abstract from Unknown event, Asilomar, USA.
Sadeghi - Hashjin, G., Folkerts, G., Henricks, P. A. J., & Nijkamp, F. P. (1998). Mast cell stabilizers inhibit chemiluminescence production by alveolar macrophages. R332-R332. Abstract from Unknown event, Asilomar, USA.
Hirschmann, J., Hammermann, R., Folkerts, G., Nijkamp, F. P., Gleich, G. J., Wessler, I., & Racke, K. (1998). .Inhibition of L-arginine transport in rat and guinea-pig alveolar macrophages (AM) by poly-cationic peptides.. 177P-177P. Abstract from Unknown event, Asilomar, USA.
Muijsers, R. B. R., de Kimpe, J. J., van der Linde, H. J., Folkerts, G., Postma, D. S., & Nijkamp, F. P. (1998). Modulation of endogenous nitric oxide and peroxynitrite formation by murine J774 macrophages. 112-112. Abstract from Unknown event, Asilomar, USA.
1997
Wetenschappelijke publicaties
Muijsers, R. B., Folkerts, G., Henricks, P. A., Sadeghi-Hashjin, G., & Nijkamp, F. P. (1997). Peroxynitrite: a two-faced metabolite of nitric oxide. Life Sciences, 60(21), 1833-1845.
Folkerts, G., & Nijkamp, F. P. (1997). Viral infection and asthma; the modulatory role of nitric oxide on prostaglandin H synthase. In A. Szezeklik, R. Gryglewski, & J. R. Vane (Eds.), Lung Biology in Health and Disease (pp. 231-251). Marcel Dekker.
Nijkamp, F. P., & Folkerts, G. (1997). Nitric oxide: initiator and modulator. Clinical and Experimental Allergy, 27, 347-350.
Folkerts, G., Visser, E. J., & Nijkamp, F. P. (1997). Liposomes enhance guinea pig tracheal relaxations induced by beta-receptor stimulation. International Review of Allergology and Clinical Immunology, 3, 178-182.
Folkerts, G., van der Linde, H. J., & Nijkamp, F. P. (1997). Pharmacological evidence that nitric oxide and cholinesterase in the epithelial layer suppresses the acetylcholine-induced contractions in guinea-pig airways. British Journal of Pharmacology, 120, 59P-59P.
Folkerts, G., van der Linde, H. J., & Nijkamp, F. P. (1997). Overview of experimental animal respiratory viral provocation models. In D. P. Skoner (Ed.), Lung Biology in Health and Disease Marcel Dekker.
Folkerts, G., Visser, E. J., Nijkamp, F. P., Ladenius, A. R. C., van der Linde, H. J., & van Rooijen, N. (1997). Partial elimination and selective in situ activation of guinea pig alveolar macrophages using liposomes. International Review of Allergology and Clinical Immunology, 3, 132-138.
Overige resultaten
van Heuven-Nolsen, D., Denee, J. H., Folkerts, G., & Nijkamp, F. P. (1997). Experimental virus infection induces airway hyperresponsiveness to bradykinin in guinea pigs. A63-A63. Abstract from Unknown event, Asilomar, USA.
Daffonchio, L., Folkerts, G., & Nijkamp, F. P. (1997). Effect of ketoprofen lysine salt on virus induced airway inflammation in guinea-pigs. 26-26. Abstract from Unknown event, Asilomar, USA.
de Kimpe, J. J., Muijsers, R. B. R., van Heuven-Nolsen, D., Folkerts, G., & Nijkamp, F. P. (1997). Nitric oxide rather than peroxynitrite after gram positive cell wall components. 102P-102P. Abstract from Unknown event, Asilomar, USA.
1996
Wetenschappelijke publicaties
Figini, M., Ricciardolo, F. L. M., Javdan, P., Nijkamp, F. P., Emanueli, C., Pradelles, P., Folkerts, G., & Geppetti, P. (1996). Evidence that epithelium-derived relaxing factor released by bradykinin in the guinea pig trachea is nitric oxide. American Journal of Respiratory and Critical Care Medicine, 153(3), 918-923.
Sadeghi-Hashjin, G., Folkerts, G., Henricks, P. A., van de Loo, P. G., Dik, I. E., & Nijkamp, F. P. (1996). Relaxation of guinea-pig trachea by sodium nitroprusside: cyclic GMP and nitric oxide not involved. British Journal of Pharmacology, 118(3), 466-470.
Sadeghi-Hashjin, G., Henricks, P. A., Folkerts, G., Verheyen, A. K., van der Linde, H. J., & Nijkamp, F. P. (1996). Bovine tracheal responsiveness in vitro: role of the epithelium and nitric oxide. European Respiratory Journal, 9(11), 2286-2293. https://doi.org/10.1183/09031936.96.09112286
Folkerts, G., Sadeghi - Hashjin, G., Henricks, P. A. J., van der Linde, H. J., van Ark, I., Verheyen, A. K. C. P., & Nijkamp, F. P. (1996). Peroxynitrite induces hyperresponsiveness of the guinea pig airways in vitro and in vivo. In J. Stamler, S. Gross, S. Moncada, & A. E. Higgs (Eds.), The Biology of Nitric Oxide (part 5) (pp. 220). Ponthart Press.
Sadeghi-Hashjin, G., Folkerts, G., Henricks, P. A. J., Van De Loo, P. G. F., Van Der Linde, H. J., Dik, I. E. M., & Nijkamp, F. P. (1996). Induction of guinea pig airway hyperresponsiveness by inactivation of guanylate cyclase. European Journal of Pharmacology, 302(1-3), 109-115. https://doi.org/10.1016/0014-2999(96)00081-7
Figini, M., Ricciardolo, F. L. M., Javdan, P., Nijkamp, F. P., Emanueli, C., Pradelles, P., Folkerts, G., & Geppetti, P. (1996). Evidence that epithelium-derived relaxing factor is released by bradykin in the guinea pig trachea is nitric oxide. American Journal of Respiratory and Critical Care Medicine, 153, 918-923.
Sadeghi-Hashjin, G., Folkerts, G., Henricks, P. A. J., Verheyen, A. K. C. P., Van Der Linde, H. J., Van Ark, I., Coene, A., & Nijkamp, F. P. (1996). Peroxynitrite induces airway hyperresponsiveness in guinea pigs in vitro and in vivo. American Journal of Respiratory and Critical Care Medicine, 153(5), 1697-1701.
Overige resultaten
van Heuven-Nolsen, D., de Vlieger, J. F., van der Linde, H. J., Folkerts, G., & Nijkamp, F. P. (1996). The bradykinin antagonist HOE 140 prevents the virus-induced airway hyperresponsiveness in guinea pigs.. Abstract from Unknown event, Asilomar, USA.
Sadeghi - Hashjin, G., Henricks, P. A. J., Folkerts, G., & Nijkamp, F. P. (1996). Bovine tracheal responsiveness in vitro: no evidence for a role of nitric oxide.. Abstract from Unknown event, Asilomar, USA.
Sadeghi - Hashjin, G., Folkerts, G., Henricks, P. A. J., van de Loo, P. G. F., van der Linde, H. J., & Nijkamp, F. P. (1996). Inhibition of cyclic GMP synthesis induces airway hyperresponsiveness in the guinea-pig.. Abstract from Unknown event, Asilomar, USA.
Sadeghi - Hashjin, G., Folkerts, G., Henricks, P. A. J., van der Linde, H. J., Verheyen, A. K. C. P., Coene, A., van Ark, I., & Nijkamp, F. P. (1996). Peroxynitrite-induced airway hyperresponsiveness in guinea pigs is associated with increased major basic protein levels and epithelium desquamation.. Abstract from Unknown event, Asilomar, USA.
1995
Wetenschappelijke publicaties
Van Oosterhout, A. J. M., Van Ark, I., Folkerts, G., Van Der Linde, H. J., Savelkoul, H. F. J., Verheyen, A. K. C. P., & Nijkamp, F. P. (1995). Antibody to interleukin-5 inhibits virus-induced airway hyperresponsiveness to histamine in guinea pigs. American Journal of Respiratory and Critical Care Medicine, 151(1), 177-183.
Ladenuis, A. R. C., Folkerts, G., Van der Linde, H. J., & Nijkamp, F. P. (1995). Potentiation by viral respiratory infection of ovalbumin-induced guinea-pig tracheal hyperresponsiveness: Role for tachykinins. British Journal of Pharmacology, 115(6), 1048-1052.
Folkerts, G., van der Linde, H. J., & Nijkamp, F. P. (1995). Virus-induced airway hyperresponsiveness in guinea pigs is related to a deficiency in nitric oxide. Journal of Clinical Investigation, 95(1), 26-30. https://doi.org/10.1172/JCI117649
Folkerts, G., & Nijkamp, F. P. (1995). Virus-induced airway hyperresponsiveness. Role of inflammatory cells and mediators. American Journal of Respiratory and Critical Care Medicine, 151(5), 1666-73; discussion 1673-4. https://doi.org/10.1164/ajrccm.151.5.7735631
Folkerts, G., van der Linde, H., Verheyen, A. K., & Nijkamp, F. P. (1995). Endogenous nitric oxide modulation of potassium-induced changes in guinea-pig airway tone. British Journal of Pharmacology, 115(7), 1194-1198.
Folkerts, G., Van der Linde, H., Van de Loo, P. G., Engels, F., & Nijkamp, F. P. (1995). Leukotrienes mediate tracheal hyperresponsiveness after nitric oxide synthesis inhibition. European Journal of Pharmacology, 285(2), R1-2.
Hashjin, G. S., Henricks, P. A. J., Folkerts, G., & Nijkamp, F. P. (1995). Preparation of bovine tracheal smooth muscle for in vitro pharmacological studies. Journal of Pharmacological and Toxicological Methods, 34(2), 103-108. https://doi.org/10.1016/1056-8719(95)00043-H
Overige resultaten
Nijkamp, F. P., & Folkerts, G. (1995). Nitric oxide and bronchial hyperresponsiveness. 81-96.
1994
Wetenschappelijke publicaties
Nijkamp, F. P., & Folkerts, G. (1994). Nitric oxide and bronchial reactivity. Clinical and Experimental Allergy, 24(10), 905-14.
1993
Wetenschappelijke publicaties
Folkerts, G., De Clerck, F., Reijnart, I., Span, P., & Nijkamp, F. P. (1993). Virus-induced airway hyperresponsiveness in the guinea-pig: possible involvement of histamine and inflammatory cells. British Journal of Pharmacology, 108(4), 1083-1093.
Folkerts, G., Verheyen, A. K., Geuens, G. M., Folkerts, H. F., & Nijkamp, F. P. (1993). Virus-induced changes in airway responsiveness, morphology, and histamine levels in guinea pigs. American Review of Respiratory Disease, 147(6 Pt 1), 1569-77. https://doi.org/10.1164/ajrccm/147.6_Pt_1.1569
Folkerts, G., van der Linde, H. J., Omini, C., & Nijkamp, F. P. (1993). Virus-induced airway inflammation and hyperresponsiveness in the guinea-pig is inhibited by levodropropizine. Naunyn-Schmiedeberg's Archives of Pharmacology, 348(2), 213-9.
Nijkamp, F. P., van der Linde, H. J., & Folkerts, G. (1993). Nitric oxide synthesis inhibitors induce airway hyperresponsiveness in the guinea pig in vivo and in vitro. Role of the epithelium. American Review of Respiratory Disease, 148(3), 727-34. https://doi.org/10.1164/ajrccm/148.3.727
1992
Wetenschappelijke publicaties
Folkerts, G., Verheyen, A., & Nijkamp, F. P. (1992). Viral infection in guinea pigs induces a sustained non-specific airway hyperresponsiveness and morphological changes of the respiratory tract. European Journal of Pharmacology: Environmental Toxicology and Pharmacology, 228(2-3), 121-130.
Folkerts, G., Verheyen, A., Janssen, M., & Nijkamp, F. P. (1992). Virus-induced airway hyperresponsiveness in the guinea pig can be transferred by bronchoalveolar cells. Journal of Allergy and Clinical Immunology, 90(3 Pt 1), 364-72.
Folkerts, G., Van Esch, B., Janssen, M., & Nijkamp, F. P. (1992). Virus-induced airway hyperresponsiveness in guinea pigs in vivo: study of broncho-alveolar cell number and activity. European Journal of Pharmacology, 228(4), 219-227.
1990
Wetenschappelijke publicaties
Folkerts, G., van Esch, B., Janssen, M., & Nijkamp, F. P. (1990). Superoxide production by broncho-alveolar cells is diminished in parainfluenza-3 virus treated guinea pigs. Agents and actions. Supplements, 31, 139-142.
Overige resultaten
Folkerts, G., & Nijkamp, F. P. (1990). Parainfluenza-3 infection of the guinea pig airways induces respiratory airway hyperreactivity in vitro. 261-263.
Folkerts, G., Van Esch, B., & Nijkamp, F. P. (1990). Does stimulation of broncho-alveolar cells by viruses lead to respiratory airway hyperreactivity in the guinea pig?. 188-189.
Folkerts, G., Janssen, M., & Nijkamp, F. P. (1990). Parainfluenza-3 induced hyperreactivity of the guinea pig trachea coincides with an increased number of broncho-alveolar cells. 159S-161S.
1989
Wetenschappelijke publicaties
Nijkamp, F. P., Folkerts, G., Beetens, J. R., & De Clerck, F. (1989). Suppression of PAF-induced bronchoconstriction in the guinea-pig by oxatomide: mechanism of action. Naunyn-Schmiedeberg's Archives of Pharmacology, 340(1), 111-118. https://doi.org/10.1007/BF00169216
Folkerts, G., & Nijkamp, F. P. (1989). Bronchial hyperreactivity induced by parainfluenza 3 is partly prevented by atropine. Agents and Actions, 26(1-2), 66-67.
Folkerts, G., Engels, F., & Nijkamp, F. P. (1989). Respiratory airway hyperreactivity coincides with decreased epithelium-derived PGE2. Agents and Actions, 26(1-2), 68-69.
Folkerts, G., Engels, F., & Nijkamp, F. P. (1989). Endotoxin-induced hyperreactivity of the guinea-pig isolated trachea coincides with decreased prostaglandin E2production by the epithelial layer. British Journal of Pharmacology, 96(2), 388-394.
Nijkamp, F. P., Folkerts, G., Beetens, J. R., & De Clerck, F. (1989). Supression of PAF-induced bronchoconstriction in the guinea-pig by oxatomide: Mechanism of action. Naunyn-Schmiedeberg's Archives of Pharmacology, 340(1), 111-118.
1988
Wetenschappelijke publicaties
Folkerts, G., & Nijkamp, F. P. (1988). Effect of arachidonic acid metabolites on intact and epithelium-denuded tracheal spirals of endotoxin-treated guinea pigs. Agents and Actions, 23(1-2), 91-93.
Folkerts, G., Henricks, P., & Nijkamp, F. P. (1988). Inflammatory reactions in the respiratory airways of the guinea pig do not necessarily induce bronchial hyperreactivity. Agents and Actions, 23(1-2), 94-96.
Loesberg, C., Folkerts, G., & Nijkamp, F. P. (1988). Effects of dietary linoleic acid on beta-adrenergic responsiveness of the guinea pig respiratory system. Prostaglandins, Leukotrienes and Essential Fatty Acids, 34(2), 127-134. https://doi.org/10.1016/0952-3278(88)90074-9
Van Oosterhout, A. J. M., Folkerts, G., Ten Have, G. A. M., & Nijkamp, F. P. (1988). Involvement of the spleen in the endotoxin-induced deterioration of the respiratory airway and lymphocyte β-adrenergic systems of the guinea pig. European Journal of Pharmacology, 147(3), 421-429.
Van Oosterhout, A. J. M., Woutersen-Van Nijnanten, F. M. A., Folkerts, G., & Nijkamp, F. P. (1988). Effects of anterior hypothalamic lesions and sham-operations on bacterial endotoxin-induced non-specific airway hyperreactivity in vivo and in vitro. British Journal of Pharmacology, 94(3), 908-916.
Folkerts, G., Henricks, P. A. J., Slootweg, P. J., & Nijkamp, F. P. (1988). Endotoxin-induced inflammation and injury of the guinea pig respiratory airways cause bronchial hyporeactivity. American Review of Respiratory Disease, 137(6), 1441-1448.
1987
Wetenschappelijke publicaties
Engels, F., Folkerts, G., Van Heuven-Nolsen, D., & Nijkamp, F. P. (1987). Haemophilus influenzae-induced decreases in lung β-adrenoceptor function and number coincide with decreases in spleen noradrenaline. Naunyn-Schmiedeberg's Archives of Pharmacology, 336(3), 274-279.
1986
Wetenschappelijke publicaties
Van Heuven-Nolsen, D., Folkerts, G., De Wildt, D. J., & Nijkamp, F. P. (1986). The influence of Bordetella pertussis and its constituents on the beta-adrenergic receptor in the guinea pig respiratory system. Life Sciences, 38(8), 677-685. https://doi.org/10.1016/0024-3205(86)90581-3
Folkerts, G., & Nijkamp, F. P. (1986). Induction of guinea pig respiratory airway hyperreactivity by Haemophilus influenzae: Role of the histaminergic and cholinergic receptor systems. Agents and Actions, 17(3-4), 399-400.
Loesberg, C., Folkerts, G., Woutersen-van Nijnanten, F. M. A., & Nijkamp, F. P. (1986). Effects of dietary poly-unsaturated fatty acids on the β-adrenergic receptor reactivity in the guinea pig respiratory system. Agents and Actions, 19(5-6), 359-360. https://doi.org/10.1007/BF01971254
Nijkamp, F. P., & Folkerts, G. (1986). Reversal of arachidonic acid-induced guinea-pig tracheal relaxation into contraction after epithelium removal. European Journal of Pharmacology, 131(2-3), 315-316. https://doi.org/10.1016/0014-2999(86)90591-1
1985
Wetenschappelijke publicaties
Folkerts, G., & Nijkamp, F. P. (1985). Haemophilus influenzae induces a potentiated increase in guinea-pig pulmonary resistance to histamine. European Journal of Pharmacology, 119(1-2), 117-120. https://doi.org/10.1016/0014-2999(85)90329-2
1983
Wetenschappelijke publicaties
Folkerts, G., Nijkamp, F. P., & van Oosterhout, A. J. M. (1983). Induction in guinea‐pigs of airway hyperreactivity and decreased lung β‐adrenoceptor number by 15‐hydroperoxy‐arachidonic acid. British Journal of Pharmacology, 80(4), 597-599. https://doi.org/10.1111/j.1476-5381.1983.tb10047.x