Publicaties
2024
Wetenschappelijke publicaties
Mandigers, P., Opmeer, Y., Alf, V., Diane Shelton, G., van Steenbeek, F., Rozendom, C., van Kooten, P., Rutten, VP., Grinwis, G., Hytönen, M. K., Rosati, M., Fieten, H., Lohi, H., Leegwater, P., & Matiasek, K. (2024). Polymyositis in the Dutch Kooikerdog. Abstract from 36th ESVN-ECVN Congress 2024, Porto, Portugal.
Boeykens, F., Abitbol, M., Anderson, H., Dargar, T., Ferrari, P., Fox, P. R., Hayward, J. J., Häggström, J., Davison, S., Kittleson, M. D., van Steenbeek, F., Ljungvall, I., Lyons, L. A., Longeri, M., Ohlsson, Å., Peelman, L., Dufaure de Citres, C., Smets, P., Turba, M. E., & Broeckx, B. J. G. (2024). Corrigendum: Classification of feline hypertrophic cardiomyopathy-associated gene variants according to the American College of Medical Genetics and Genomics guidelines (Frontiers in Veterinary Science, (2024), 11, (1327081), 10.3389/fvets.2024.1327081). Frontiers in Veterinary Science, 11, Article 1458433. https://doi.org/10.3389/fvets.2024.1458433
Leegwater, P., Opmeer, Y., van Steenbeek, F., Rozendom, C., van Kooten, P., Rutten, VP., Fieten, H., Hytönen, M. K., Lohi, H., & Mandigers, P. (2024). Polymyositis in Kooiker dogs is associated with a 39 kb deletion upstream the IL21/IL2 genes. 100. Abstract from ICCFGG 2024, Helsinki, Finland.
https://research-portal.uu.nl/ws/files/227681775/ICCFGG_2024_Programme_Abstract_Book_Leegwater.pdf
https://research-portal.uu.nl/ws/files/227681775/ICCFGG_2024_Programme_Abstract_Book_Leegwater.pdf
Veltrop, R. J. A., Kukk, M. M., Topouzidou, K., Didden, L., Muchir, A., van Steenbeek, F. G., Schurgers, L. J., & Harakalova, M. (2024). From gene to mechanics: a comprehensive insight into the mechanobiology of LMNA mutations in cardiomyopathy. Cell Communication and Signaling, 22(1), Article 197. https://doi.org/10.1186/s12964-024-01546-5
https://dspace.library.uu.nl/bitstream/handle/1874/437914/s12964-024-01546-5.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/437914/s12964-024-01546-5.pdf?sequence=1
Boeykens, F., Abitbol, M., Anderson, H., Dargar, T., Ferrari, P., Fox, P. R., Hayward, J. J., Häggström, J., Davison, S., Kittleson, M. D., van Steenbeek, F., Ljungvall, I., Lyons, L. A., Longeri, M., Ohlsson, Å., Peelman, L., Dufaure de Citres, C., Smets, P., Turba, M. E., & Broeckx, B. J. G. (2024). Classification of feline hypertrophic cardiomyopathy-associated gene variants according to the American College of Medical Genetics and Genomics guidelines. Frontiers in Veterinary Science, 11, Article 1327081. https://doi.org/10.3389/fvets.2024.1327081
https://dspace.library.uu.nl/bitstream/handle/1874/436671/fvets-11-1327081.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/436671/fvets-11-1327081.pdf?sequence=1
2023
Wetenschappelijke publicaties
Hilderink, S., Schuldt, M., Goebel, M., Jansen, V. J., Manders, E., Moorman, S., Dorsch, L. M., van Steenbeek, F. G., van der Velden, J., & Kuster, D. W. D. (2023). Characterization of heterozygous and homozygous mouse models with the most common hypertrophic cardiomyopathy mutation MYBPC3 c.2373InsG in the Netherlands. Journal of Molecular and Cellular Cardiology, 185, 65-76. https://doi.org/10.1016/j.yjmcc.2023.10.008
Niskanen, J. E., Ohlsson, Å., Ljungvall, I., Drögemüller, M., Ernst, R. F., Dooijes, D., van Deutekom, H. W. M., van Tintelen, J. P., Snijders Blok, C. J. B., van Vugt, M., van Setten, J., Asselbergs, F. W., Petrič, A. D., Salonen, M., Hundi, S., Hörtenhuber, M., Kere, J., Pyle, W. G., Donner, J., ... Lohi, H. (2023). Identification of novel genetic risk factors of dilated cardiomyopathy: from canine to human. Genome Medicine, 15(1), Article 73. https://doi.org/10.1186/s13073-023-01221-3
https://dspace.library.uu.nl/bitstream/handle/1874/432054/s13073-023-01221-3.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/432054/s13073-023-01221-3.pdf?sequence=1
van den Berg, M., Kooistra, H., Grinwis, G., Nicoli, S., Golinelli, S., Stammeleer, L., van Wolferen, M., Timmermans - Sprang, E., Zandvliet, M., van Steenbeek, F., & Galac, S. (2023). Whole transcriptome analysis of canine pheochromocytoma and paraganglioma. Frontiers in Veterinary Science, 10, Article 1155804. https://doi.org/10.3389/fvets.2023.1155804
Mandigers, P. J. J., Stehling, O., Vos-Loohuis, M., Van Steenbeek, F. G., Lill, R., & Leegwater, P. A. (2023). A novel IBA57 variant is associated with mitochondrial iron-sulfur protein deficiency and necrotizing myelopathy in dogs. Frontiers in Genetics, 14, Article 1190222. https://doi.org/10.3389/fgene.2023.1190222
Spanjersberg, T. C. F., Oosterhoff, L. A., Kruitwagen, H. S., van den Dungen, N. A. M., Vernooij, J. C. M., Asselbergs, F. W., Mokry, M., Spee, B., Harakalova, M., & van Steenbeek, F. G. (2023). Locational memory of macrovessel vascular cells is transcriptionally imprinted. Scientific Reports, 13(1), 13028. Article 13028. https://doi.org/10.1038/s41598-023-38880-6
Gaar-Humphreys, K. R., van den Brink, A., Wekking, M., Asselbergs, F. W., van Steenbeek, F. G., Harakalova, M., & Pei, J. (2023). Targeting lipid metabolism as a new therapeutic strategy for inherited cardiomyopathies. Frontiers in Cardiovascular Medicine, 10, Article 1114459. https://doi.org/10.3389/fcvm.2023.1114459
Bouwmeester, M. C., Tao, Y., Proença, S., van Steenbeek, F. G., Samsom, R.-A., Nijmeijer, S. M., Sinnige, T., van der Laan, L. J. W., Legler, J., Schneeberger, K., Kramer, N. I., & Spee, B. (2023). Drug Metabolism of Hepatocyte-like Organoids and Their Applicability in In Vitro Toxicity Testing. Molecules (Basel, Switzerland), 28(2), Article 621. https://doi.org/10.3390/molecules28020621
Sanders, K., Kooistra, H. S., van den Heuvel, M., Mokry, M., Grinwis, G. C. M., van den Dungen, N. A. M., van Steenbeek, F. G., & Galac, S. (2023). Transcriptome sequencing reveals two subtypes of cortisol-secreting adrenocortical tumours in dogs and identifies CYP26B1 as a potential new therapeutic target. Veterinary and Comparative Oncology, 21(1), 100-110. https://doi.org/10.1111/vco.12871
2022
Wetenschappelijke publicaties
Korff, S., Mostaguir, K., Beghetti, M., D'Antiga, L., Debray, D., Franchi-Abella, S., Gonzales, E., Guerin, F., Hachulla, A.-L., Lambert, V., Makrythanasis, P., Roduit, N., Savale, L., Senat, M.-V., Spaltenstein, J., van Steenbeek, F., Wildhaber, B. E., Zwahlen, M., & McLin, V. A. (2022). International registry of congenital porto-systemic shunts: a multi-centre, retrospective and prospective registry of neonates, children and adults with congenital porto-systemic shunts. Orphanet Journal of Rare Diseases, 17(1), Article 284. https://doi.org/10.1186/s13023-022-02412-8
Gaar-Humphreys, K. R., Spanjersberg, T. C. F., Santarelli, G., Grinwis, G. C. M., Szatmári, V., Roelen, B. A. J., Vink, A., Tintelen, J. P. V., Asselbergs, F. W., Fieten, H., Harakalova, M., & Steenbeek, F. G. V. (2022). Genetic Basis of Dilated Cardiomyopathy in Dogs and Its Potential as a Bidirectional Model. Animals, 12(13), 1-18. Article 1679. https://doi.org/10.3390/ani12131679
van der Velden, J., Asselbergs, F. W., Bakkers, J., Batkai, S., Bertrand, L., Bezzina, C. R., Bot, I., Brundel, B., Carrier, L., Chamuleau, S., Ciccarelli, M., Dawson, D., Davidson, S. M., Dendorfer, A., Duncker, D. J., Eschenhagen, T., Fabritz, L., Falcão-Pires, I., Ferdinandy, P., ... Thum, T. (2022). Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC working group on myocardial function and the ESC Working Group on Cellular Biology of the Heart. Cardiovascular Research, 118(15), 3016-3051. https://doi.org/10.1093/cvr/cvab370
https://dspace.library.uu.nl/bitstream/handle/1874/425613/cvab370.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/425613/cvab370.pdf?sequence=1
Vakpublicaties
van Steenbeek, F. (2022). Hoe de grote boze wolf verlatingsangst kreeg. In Epigenetica: Hetzelfde DNA, maar toch anders. Hoe kan dat? (pp. 61-62). Stichting Bio-Wetenschappen en Maatschappij. https://www.biomaatschappij.nl/artikel/hoe-de-grote-boze-wolf-verlatingsangst-kreeg/
2021
Wetenschappelijke publicaties
Pei, J., Schuldt, M., Nagyova, E., Gu, Z., El Bouhaddani, S., Yiangou, L., Jansen, M., Calis, J. J. A., Dorsch, L. M., Blok, C. S., van den Dungen, N. A. M., Lansu, N., Boukens, B. J., Efimov, I. R., Michels, M., Verhaar, M. C., de Weger, R., Vink, A., van Steenbeek, F. G., ... Harakalova, M. (2021). Multi-omics integration identifies key upstream regulators of pathomechanisms in hypertrophic cardiomyopathy due to truncating MYBPC3 mutations. Clinical Epigenetics, 13(1), 1-20. Article 61. https://doi.org/10.1186/s13148-021-01043-3
Dog Biomedical Variant Database Consortium (2021). Improving the resolution of canine genome-wide association studies using genotype imputation: A study of two breeds. Animal Genetics, 52(5), 703-713. https://doi.org/10.1111/age.13117
Mandigers, P. J. J., Van Steenbeek, F. G., Bergmann, W., Vos-Loohuis, M., & Leegwater, P. A. (2021). A knockout mutation associated with juvenile paroxysmal dyskinesia in Markiesje dogs indicates SOD1 pleiotropy. Human Genetics, 140(11), 1547-1552. https://doi.org/10.1007/s00439-021-02271-6
2020
Wetenschappelijke publicaties
Ribitsch, I., Baptista, P. M., Lange-Consiglio, A., Melotti, L., Patruno, M., Jenner, F., Schnabl-Feichter, E., Dutton, L. C., Connolly, D. J., van Steenbeek, F. G., Dudhia, J., & Penning, L. C. (2020). Large Animal Models in Regenerative Medicine and Tissue Engineering: To Do or Not to Do. Frontiers in Bioengineering and Biotechnology, 8, Article 972. https://doi.org/10.3389/fbioe.2020.00972
Wu, X., den Boer, E. R., Vos-Loohuis, M., Monroe, G. R., Nijman, I. J., van Steenbeek, F. G., Leegwater, P. A. J., & Fieten, H. (2020). Investigation of Genetic Modifiers of Copper Toxicosis in Labrador Retrievers. Life (Basel, Switzerland), 10(11), Article 266. https://doi.org/10.3390/life10110266
Ye, S., Boeter, J. W. B., Mihajlovic, M., van Steenbeek, F. G., van Wolferen, M. E., Oosterhoff, L. A., Marsee, A., Caiazzo, M., van der Laan, L. J. W., Penning, L. C., Vermonden, T., Spee, B., & Schneeberger, K. (2020). A Chemically Defined Hydrogel for Human Liver Organoid Culture. Advanced Functional Materials, 30(48), Article 2000893. https://doi.org/10.1002/adfm.202000893
Kruitwagen, H. S., Oosterhoff, L. A., van Wolferen, M. E., Chen, C., Nantasanti Assawarachan, S., Schneeberger, K., Kummeling, A., van Straten, G., Akkerdaas, I. C., Vinke, C. R., van Steenbeek, F. G., van Bruggen, L. W. L., Wolfswinkel, J., Grinwis, G. C. M., Fuchs, S. A., Gehart, H., Geijsen, N., Vries, R. G., Clevers, H., ... Spee, B. (2020). Long-Term Survival of Transplanted Autologous Canine Liver Organoids in a COMMD1-Deficient Dog Model of Metabolic Liver Disease. Cells, 9(2), 1-16. Article 410. https://doi.org/10.3390/cells9020410
Schneeberger, K., Sánchez-Romero, N., Ye, S., van Steenbeek, F. G., Oosterhoff, L. A., Pla Palacin, I., Chen, C., van Wolferen, M. E., van Tienderen, G., Lieshout, R., Colemonts-Vroninks, H., Schene, I., Hoekstra, R., Verstegen, M. M. A., van der Laan, L. J. W., Penning, L. C., Fuchs, S. A., Clevers, H., De Kock, J., ... Spee, B. (2020). Large-scale Production of LGR5-positive Bipotential Human Liver Stem Cells. Hepatology, 72(1), 257-270. https://doi.org/10.1002/hep.31037
2019
Wetenschappelijke publicaties
Jagannathan, V., Drögemüller, C., Leeb, T., Aguirre, G., André, C., Bannasch, D., Becker, D., Davis, B., Ekenstedt, K., Faller, K., Forman, O., Friedenberg, S., Furrow, E., Giger, U., Hitte, C., Hytönen, M., Lohi, H., Mellersh, C., Mickelson, J. R., ... Wade, C. (2019). A comprehensive biomedical variant catalogue based on whole genome sequences of 582 dogs and eight wolves. Animal Genetics, 50(6), 695-704. https://doi.org/10.1111/age.12834
Keijser, S. F. A., Vernooij, J. C. M., van Garderen, E., van Rooijen, P., Fieten, H., van Steenbeek, F. G., Hesselink, J. W., & Nielen, M. (2019). Quantification of the health-status of the Dutch Labrador retriever population. Preventive Veterinary Medicine, 171, Article 104764. https://doi.org/10.1016/j.prevetmed.2019.104764
https://dspace.library.uu.nl/bitstream/handle/1874/384847/Quantification.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/384847/Quantification.pdf?sequence=1
Oosterhoff, L. A., Kruitwagen, H. S., van Wolferen, M. E., van Balkom, B. W. M., Mokry, M., Lansu, N., van den Dungen, N. A. M., Penning, L. C., Spanjersberg, T. C. F., de Graaf, J. W., Veenendaal, T., Zomerdijk, F., Fledderus, J. O., Spee, B., & van Steenbeek, F. G. (2019). Characterization of Endothelial and Smooth Muscle Cells From Different Canine Vessels. Frontiers in Physiology, 10, Article 101. https://doi.org/10.3389/fphys.2019.00101
2018
Wetenschappelijke publicaties
Keijser, S. F. A., Fieten, H., Vos-Loohuis, M., Piek, C. J., Anderson, H., Donner, J., Scholten, I., Nielen, M., Hesselink, J. W., & van Steenbeek, F. G. (2018). DNA panel screening as a potential tool to monitor health and inbreeding in a small, closed dog population. Canine genetics and epidemiology, 5(12), Article 12. https://doi.org/10.1186/s40575-018-0068-6
den Toom, M. L., Grinwis, G., Boroffka, S. A., de Jong, P. A., van Steenbeek, F. G., & Szatmári, V. (2018). Pulmonary veno-occlusive disease as a cause of severe pulmonary hypertension in a dog. Acta Veterinaria Scandinavica, 60(1), Article 78. https://doi.org/10.1186/s13028-018-0433-1
Keijser, S. F. A., Vernooij, J. C. M., Rothuizen, J., Fieten, H., Nielen, M., Hesselink, J. W., & van Steenbeek, F. G. (2018). PETscan: measuring incidence of disease phenotypes to prioritize genetic studies in companion animals. Animal Genetics, 49(5), 492-495. https://doi.org/10.1111/age.12707
Van den Bossche, L., van Steenbeek, F. G., Weber, M. F., Spee, B., Penning, L. C., van Sluijs, F. J., Zomerdijk, F., Groot Koerkamp, M. J. A., Rothuizen, J., Burgener, I. A., & Kummeling, A. (2018). Genome-wide based model predicting recovery from portosystemic shunting after liver shunt attenuation in dogs. Journal of Veterinary Internal Medicine, 32(4), 1343-1352. https://doi.org/10.1111/jvim.15140
2017
Wetenschappelijke publicaties
Stassen, Q. E. M., Koskinen, L. L. E., van Steenbeek, F. G., Seppälä, E. H., Jokinen, T. S., Prins, P. G. M., Bok, H. G. J., Zandvliet, M. M. J. M., Vos-Loohuis, M., Leegwater, P. A. J., & Lohi, H. (2017). Paroxysmal Dyskinesia in Border Terriers: Clinical, Epidemiological, and Genetic Investigations. Journal of Veterinary Internal Medicine, 31(4), 1123-1131. https://doi.org/10.1111/jvim.14731
Van den Bossche, L., Schoonenberg, V. A. C., Burgener, I. A., Penning, L. C., Schrall, I. M., Kruitwagen, H. S., van Wolferen, M. E., Grinwis, G. C. M., Kummeling, A., Rothuizen, J., van Velzen, J. F., Stathonikos, N., Molenaar, M. R., Helms, B. J., Brouwers, J. F. H. M., Spee, B., & van Steenbeek, F. G. (2017). Aberrant hepatic lipid storage and metabolism in canine portosystemic shunts. PLoS One, 12(10), Article e0186491. https://doi.org/10.1371/journal.pone.0186491
Dirksen, K., Spee, B., Penning, L. C., van den Ingh, T. S. G. A. M., Burgener, I. A., Watson, A. L., Groot Koerkamp, M., Rothuizen, J., van Steenbeek, F. G., & Fieten, H. (2017). Gene expression patterns in the progression of canine copper-associated chronic hepatitis. PLoS One, 12(5), e0176826. https://doi.org/10.1371/journal.pone.0176826
Keijser, S. F. A., Meijndert, L. E., Fieten, H., Carrière, B. J., van Steenbeek, F. G., Leegwater, P. A. J., Rothuizen, J., & Nielen, M. (2017). Disease burden in four populations of dog and cat breeds compared to mixed-breed dogs and European shorthair cats. Preventive Veterinary Medicine, 140, 38-44. https://doi.org/10.1016/j.prevetmed.2017.02.016
https://dspace.library.uu.nl/bitstream/handle/1874/360829/1_s2.0_S0167587717301708_main.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/360829/1_s2.0_S0167587717301708_main.pdf?sequence=1
Wangdee, C., Leegwater, P. A. J., Heuven, H. C. M., van Steenbeek, F. G., Techakumphu, M., & Hazewinkel, H. A. W. (2017). Population genetic analysis and genome-wide association study of patellar luxation in a Thai population of Pomeranian dogs. Research in Veterinary Science, 111, 9-13. https://doi.org/10.1016/j.rvsc.2016.11.006
2016
Wetenschappelijke publicaties
Meneses, A. M. C., Schneeberger, K., Kruitwagen, H. S., Penning, L. C., van Steenbeek, F. G., Burgener, I. A., & Spee, B. (2016). Intestinal Organoids-Current and Future Applications. Veterinary Sciences, 3(4). https://doi.org/10.3390/vetsci3040031
Meneses, A., Schneeberger, K., Kruitwagen, H., Penning, L., van Steenbeek, F., Burgener, I., & Spee, B. (2016). Intestinal Organoids—Current and Future Applications. Veterinary Sciences, 3(4), 31. https://doi.org/10.3390/vetsci3040031
Van den Bossche, L., & van Steenbeek, F. G. (2016). Canine congenital portosystemic shunts: Disconnections dissected. Veterinary Journal, 211, 14-20. https://doi.org/10.1016/j.tvjl.2015.09.025
https://dspace.library.uu.nl/bitstream/handle/1874/346834/Canine.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/346834/Canine.pdf?sequence=1
Oosterhoff, L. A., Kruitwagen, H. S., Spee, B., & van Steenbeek, F. G. (2016). Isolation and Culture of Primary Endothelial Cells from Canine Arteries and Veins. Journal of Visualized Experiments, (117), Article e54786. https://doi.org/10.3791/54786
https://dspace.library.uu.nl/bitstream/handle/1874/346022/isolation.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/346022/isolation.pdf?sequence=1
Leegwater, P. A., Vos-Loohuis, M., Ducro, B. J., Boegheim, I. J., van Steenbeek, F. G., Nijman, I. J., Monroe, G. R., Bastiaansen, J. W. M., Dibbits, B. W., van de Goor, L. H., Hellinga, I., Back, W., & Schurink, A. (2016). Dwarfism with joint laxity in Friesian horses is associated with a splice site mutation in B4GALT7. BMC Genomics, 17, Article 839. https://doi.org/10.1186/s12864-016-3186-0
van Steenbeek, F. G., Hytönen, M. K., Leegwater, P. A. J., & Lohi, H. (2016). The canine era: the rise of a biomedical model. Animal Genetics, 47(5), 519-527. https://doi.org/10.1111/age.12460
Fieten, H., Gill, Y., Martin, A. J., Concilli, M., Dirksen, K., van Steenbeek, F. G., Spee, B., van den Ingh, T. S. G. A. M., Martens, E. C. C. P., Festa, P., Chesi, G., van de Sluis, B., Houwen, R. H. J. H., Watson, A. L., Aulchenko, Y. S., Hodgkinson, V. L., Zhu, S., Petris, M. J., Polishchuk, R. S., ... Rothuizen, J. (2016). The Menkes and Wilson disease genes counteract in copper toxicosis in Labrador retrievers: a new canine model for copper-metabolism disorders. Disease Models & Mechanisms, 9, 25-38. https://doi.org/10.1242/dmm.020263
Malagola, E., Teunissen, M., van der Laan, L. J. W., Verstegen, M., Schotanus, B. A., van Steenbeek, F. G., Penning, L. C., van Wolferen, M. E., Tryfonidou, M. A., & Spee, B. (2016). Characterization and comparison of canine multipotent stromal cells derived from liver and bone marrow. Stem Cells and Development, 35(2). https://doi.org/10.1089/scd.2015.0125
https://dspace.library.uu.nl/bitstream/handle/1874/351635/Characterization.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/351635/Characterization.pdf?sequence=1
2015
Wetenschappelijke publicaties
Szatmári, V., Teske, E., Nikkels, P. G. J., Griese, M., de Jong, P. A., Grinwis, G., Theegarten, D., Veraa, S., van Steenbeek, F. G., Drent, M., & Bonella, F. (2015). Pulmonary alveolar proteinosis in a cat. BMC Veterinary Research, 11(1), Article 302. https://doi.org/10.1186/s12917-015-0613-4
Ducro, B. J., Schurink, A., Bastiaansen, J. W. M., Boegheim, I. J. M., van Steenbeek, F. G., Vos-Loohuis, M., Nijman, I. J., Monroe, G. R., Hellinga, I., Dibbits, B. W., Back, W., & Leegwater, P. A. J. (2015). A nonsense mutation in B3GALNT2 is concordant with hydrocephalus in Friesian horses. BMC Genomics, 16(1), 761. https://doi.org/10.1186/s12864-015-1936-z
van Dongen, A. M., Heuving, S. M., Tryfonidou, M. A., van Steenbeek, F. G., Rothuizen, J., & Penning, L. C. (2015). Increased bone morphogenetic protein 7 signalling in the kidneys of dogs affected with a congenital portosystemic shunt. Veterinary Journal, 204(2), 226-228. https://doi.org/10.1016/j.tvjl.2015.03.008
https://dspace.library.uu.nl/bitstream/handle/1874/329337/S109002331.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/329337/S109002331.pdf?sequence=1
2014
Wetenschappelijke publicaties
Wangdee, C., Leegwater, P. A. J., Heuven, H. C. M., van Steenbeek, F. G., Meutstege, F. J., Meij, B. P., & Hazewinkel, H. A. W. (2014). Prevalence and genetics of patellar luxation in Kooiker dogs. Veterinary Journal, 201(3), 333-337. https://doi.org/10.1016/j.tvjl.2014.05.036
Boerkamp, K. M., van Steenbeek, F. G., Penning, L. C., Groot Koerkamp, M. J. A., van Leenen, D., Vos-Loohuis, M., Grinwis, G. C. M., & Rutteman, G. R. (2014). The two main forms of histiocytic sarcoma in the predisposed Flatcoated retriever dog display variation in gene expression. PLoS One, 9(6), Article e98258. https://doi.org/10.1371/journal.pone.0098258
van Straten, G., van Steenbeek, F. G., Grinwis, G. C. M., Favier, R. P., Kummeling, A., Gils, I. H., Fieten, H., Groot Koerkamp, M. J. A., Holstege, F. C. P., Rothuizen, J., & Spee, B. (2014). Aberrant expression and distribution of enzymes of the urea cycle and other ammonia metabolizing pathways in dogs with congenital portosystemic shunts. PLoS One, 9(6), Article e100077. https://doi.org/10.1371/journal.pone.0100077
Lavrijsen, I. C. M., Leegwater, P. A. J., Wangdee, C., van Steenbeek, F. G., Schwencke, M., Breur, G. J., Meutstege, F. J., Nijman, I. J., Cuppen, E. P. J. G., Heuven, H. C. M., & Hazewinkel, H. A. W. (2014). Genome-wide survey indicates involvement of loci on canine chromosomes 7 and 31 in patellar luxation in Flat-Coated Retrievers. BMC Genetics [E], 15, Article 15:64 . https://doi.org/10.1186/1471-2156-15-64
2013
Wetenschappelijke publicaties
van Steenbeek, F. G., Spee, B., Penning, L. C., Kummeling, A., Gils, I. H., Grinwis, G. C. M., van Leenen, D., Holstege, F. C. P., Vos-Loohuis, M., Rothuizen, J., & Leegwater, P. A. J. (2013). Altered subcellular localization of heat shock protein 90 is associated with impaired expression of the aryl hydrocarbon receptor pathway in dogs. PLoS One, 8(3), e57973. https://doi.org/10.1371/journal.pone.0057973
Boerkamp, K. M., van der Kooij, M. A., van Steenbeek, F. G., van Wolferen, M. E., Groot Koerkamp, M. J. A., van Leenen, D., Grinwis, G. C. M., Penning, L. C., Wiemer, E. A., & Rutteman, G. R. (2013). Gene expression profiling of histiocytic sarcomas in a canine model: the predisposed flatcoated retriever dog. PLoS One, 8, e71094. https://doi.org/10.1371/journal.pone.0071094
van Steenbeek, F. G., van den Bossche, L., Grinwis, G. C. M., Kummeling, A., Gils, I. H., Koerkamp, M. G., van Leenen, D., Holstege, F. C., Penning, L. C., Rothuizen, J., Leegwater, P. A. J., & Spee, B. (2013). Aberrant gene expression in dogs with portosystemic shunts. PLoS One, 8(2), e57662. https://doi.org/10.1371/journal.pone.0057662
van Steenbeek, F. G. (2013). The genetic background of congenital portosystemic shunts in dogs. [Doctoral thesis 1 (Research UU / Graduation UU), Utrecht University]. Utrecht University.
https://dspace.library.uu.nl/bitstream/handle/1874/275371/steenbeek.pdf?sequence=2
https://dspace.library.uu.nl/bitstream/handle/1874/275371/steenbeek.pdf?sequence=2
2012
Wetenschappelijke publicaties
van der Heijden, M., de Vries, M., van Steenbeek, F. G., Favier, R. P., Deijs, M., Brinkhof, B., Rothuizen, J., van der Hoek, L., & Penning, L. C. (2012). Sequence-independent VIDISCA-454 technique to discover new viruses in canine livers. Journal of Virological Methods, 185(1), 152-155. https://doi.org/10.1016/j.jviromet.2012.05.019
van Steenbeek, F. G., van den Bossche, L., Leegwater, P. A. J., & Rothuizen, J. (2012). Inherited liver shunts in dogs elucidate pathways regulating embryonic development and clinical disorders of the portal vein. Mammalian Genome, 23(1-2), 76-84. https://doi.org/10.1007/s00335-011-9364-0
https://dspace.library.uu.nl/bitstream/handle/1874/272363/mammgenome2011review.pdf?sequence=2
https://dspace.library.uu.nl/bitstream/handle/1874/272363/mammgenome2011review.pdf?sequence=2
van den Bossche, L., van Steenbeek, F. G., Favier, R. P., Kummeling, A., Leegwater, P. A. J., & Rothuizen, J. (2012). Distribution of extrahepatic congenital portosystemic shunt morphology in predisposed dog breeds. BMC Veterinary Research, (112), 10.1186/1746-6148-8-112. https://doi.org/10.1186/1746-6148-8-112
Overige resultaten
Fieten, H., van Steenbeek, F. G., Leegwater, P. A. J., Favier, R. P., & Rothuizen, J. (2012). Portosystemic vascular anomalies in dogs: genetics, diagnosis and therapeutic options. 65-65. Abstract from 58th Jahreskongress der Deutschen Gesellschaft fur Kleintiermedizin, Dusseldorf.
2011
Wetenschappelijke publicaties
Vaysse, A., Ratnakumar, A., Derrien, T., Axelsson, E., Rosengren Pielberg, G., Sigurdsson, S., Fall, T., Seppälä, E. H., Hansen, M. S., Lawley, C. T., Karlsson, E. K., Bannasch, D. L., Vilà, C., Lohi, H., Galibert, F., Fredholm, M., Häggström, O., Hedhammar, A., André, C., ... Webster, M. T. (2011). Identification of Genomic Regions Associated with Phenotypic Variation between Dog Breeds using Selection Mapping. PLoS Genetics, 7(10), Article e1002316. https://doi.org/10.1371/journal.pgen.1002316
https://dspace.library.uu.nl/bitstream/handle/1874/234168/vaysse%2520et%2520al%2520Plos%2520Genetics%2520TR2.pdf?sequence=2
https://dspace.library.uu.nl/bitstream/handle/1874/234168/vaysse%2520et%2520al%2520Plos%2520Genetics%2520TR2.pdf?sequence=2
Voorbij, A. M. W. Y., van Steenbeek, F. G., Vos-Loohuis, M., Martens, E. E. C. P., Hanson-Nilsson, J. M., van Oost, B. A., Kooistra, H. S., & Leegwater, P. A. J. (2011). A Contracted DNA Repeat in LHX3 Intron 5 Is Associated with Aberrant Splicing and Pituitary Dwarfism in German Shepherd Dogs. PLoS One, 6(11), Article e27940. https://doi.org/10.1371/journal.pone.0027940
https://dspace.library.uu.nl/bitstream/handle/1874/234182/Contracted%2520DNA%2520Repeat%2520in%2520LHX3%2520Intron%25205%2520Is%2520Associated%2520with%2520Aberrant%2520Splicing%2520and%2520Pituitary.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/234182/Contracted%2520DNA%2520Repeat%2520in%2520LHX3%2520Intron%25205%2520Is%2520Associated%2520with%2520Aberrant%2520Splicing%2520and%2520Pituitary.pdf?sequence=1
2010
Wetenschappelijke publicaties
Thitaram, C., Somgird, C., Mahasawangkul, S., Angkavanich, T., Roongsri, R., Thongtip, N., Colenbrander, B., van Steenbeek, F. G., & Lenstra, J. A. (2010). Genetic assessment of captive elephant (Elephas maximus) populations in Thailand. Conservation Genetics, 11(1), 325-330. https://doi.org/10.1007/s10592-009-0018-7
2009
Wetenschappelijke publicaties
van Steenbeek, F. G., Leegwater, P. A. J., van Sluijs, F. J., Heuven, H. C. M., & Rothuizen, J. (2009). Evidence of Inheritance of Intrahepatic Portosystemic Shunts in Irish Wolfhounds. Journal of Veterinary Internal Medicine, 23, 950-952.
2008
Wetenschappelijke publicaties
Thitaram, C., Thongtip, N., Somgird, C., Colenbrander, B., Van Boxtel, D. C. J., Van Steenbeek, F., & Lenstra, J. A. (2008). Evaluation and selection of microsatellite markers for an identification and parentage test of Asian elephants (Elephas maximus). Conservation Genetics, 9(4), 921-925. https://doi.org/10.1007/s10592-007-9406-z