Publicaties
2023
Wetenschappelijke publicaties
Eppink, M., Wapenaar, M., Crommelin, D., Hawe, A., Giezen, T., Black, A., & Tam, A. (2023). Therapeutic Proteins and Advanced Therapy Medicinal Products. In Practical Pharmaceutics: An International Guideline for the Preparation, Care and Use of Medicinal Products, Second Edition (pp. 551-590). Springer. https://doi.org/10.1007/978-3-031-20298-8_24
https://dspace.library.uu.nl/bitstream/handle/1874/436536/978-3-031-20298-8_24.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/436536/978-3-031-20298-8_24.pdf?sequence=1
Oude Blenke, E., Örnskov, E., Schöneich, C., Nilsson, G. A., Volkin, D. B., Mastrobattista, E., Almarsson, Ö., & Crommelin, D. J. A. (2023). The Storage and In-Use Stability of mRNA Vaccines and Therapeutics: Not A Cold Case. Journal of Pharmaceutical Sciences, 112(2), 386-403. https://doi.org/10.1016/j.xphs.2022.11.001
2022
Wetenschappelijke publicaties
Szebeni, J., Storm, G., Ljubimova, J. Y., Castells, M., Phillips, E. J., Turjeman, K., Barenholz, Y., Crommelin, D. J. A., & Dobrovolskaia, M. A. (2022). Applying lessons learned from nanomedicines to understand rare hypersensitivity reactions to mRNA-based SARS-CoV-2 vaccines. Nature Nanotechnology, 17(4), 337-346. https://doi.org/10.1038/s41565-022-01071-x
https://dspace.library.uu.nl/bitstream/handle/1874/426386/Applying_lessons_learned_from_nanomedicines_to_understand_rare_hypersensitivity_reactions_to_mRNA_based_SARS_CoV_2_vaccines.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/426386/Applying_lessons_learned_from_nanomedicines_to_understand_rare_hypersensitivity_reactions_to_mRNA_based_SARS_CoV_2_vaccines.pdf?sequence=1
Jiskoot, W., Hawe, A., Menzen, T., Volkin, D. B., & Crommelin, D. J. A. (2022). Ongoing Challenges to Develop High Concentration Monoclonal Antibody-based Formulations for Subcutaneous Administration: Quo Vadis? Journal of Pharmaceutical Sciences, 111(4), 861-867. https://doi.org/10.1016/j.xphs.2021.11.008
2021
Wetenschappelijke publicaties
Schoenmaker, L., Witzigmann, D., Kulkarni, J. A., Verbeke, R., Kersten, G., Jiskoot, W., & Crommelin, D. J. A. (2021). mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability. International Journal of Pharmaceutics, 601, 1-13. Article 120586. https://doi.org/10.1016/j.ijpharm.2021.120586
Crommelin, D. J. A., Volkin, D. B., Hoogendoorn, K. H., Lubiniecki, A. S., & Jiskoot, W. (2021). The Science is There: Key Considerations for Stabilizing Viral Vector-Based Covid-19 Vaccines. Journal of Pharmaceutical Sciences, 110(2), 627-634. https://doi.org/10.1016/j.xphs.2020.11.015
Crommelin, D. J. A., Anchordoquy, T. J., Volkin, D. B., Jiskoot, W., & Mastrobattista, E. (2021). Addressing the Cold Reality of mRNA Vaccine Stability. Journal of Pharmaceutical Sciences, 110(3), 997-1001. https://doi.org/10.1016/j.xphs.2020.12.006
Hoogendoorn, K. H., Crommelin, D. J. A., & Jiskoot, W. (2021). Formulation of Cell-Based Medicinal Products: A Question of Life or Death? Journal of Pharmaceutical Sciences, 110(5), 1885-1894. https://doi.org/10.1016/j.xphs.2020.07.002
2020
Wetenschappelijke publicaties
Crommelin, D. J. A., van Hoogevest, P., & Storm, G. (2020). The role of liposomes in clinical nanomedicine development. What now? Now what? Journal of controlled release : official journal of the Controlled Release Society, 318, 256-263. https://doi.org/10.1016/j.jconrel.2019.12.023
https://dspace.library.uu.nl/bitstream/handle/1874/411308/1_s2.0_S0168365919307424_main.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/411308/1_s2.0_S0168365919307424_main.pdf?sequence=1
Crommelin, D. J. A., Mastrobattista, E., Hawe, A., Hoogendoorn, K. H., & Jiskoot, W. (2020). Shifting Paradigms Revisited: Biotechnology and the Pharmaceutical Sciences. Journal of Pharmaceutical Sciences, 109(1), 30-43. https://doi.org/10.1016/j.xphs.2019.08.010
Metz, B., Michiels, T., Uittenbogaard, J., Danial, M., Tilstra, W., Meiring, H. D., Hennink, W. E., Crommelin, D. J. A., Kersten, G. F. A., & Jiskoot, W. (2020). Identification of Formaldehyde-Induced Modifications in Diphtheria Toxin. Journal of Pharmaceutical Sciences, 109(1), 543-557. https://doi.org/10.1016/j.xphs.2019.10.047
2019
Wetenschappelijke publicaties
Klein, K., Stolk, P., De Bruin, M. L., Leufkens, H. G. M., Crommelin, D. J. A., & De Vlieger, J. S. B. (2019). The EU regulatory landscape of non-biological complex drugs (NBCDs) follow-on products: Observations and recommendations. European Journal of Pharmaceutical Sciences, 133, 228-235. https://doi.org/10.1016/j.ejps.2019.03.029
2017
Wetenschappelijke publicaties
de Vrueh, R. L. A., & Crommelin, D. J. A. (2017). Reflections on the Future of Pharmaceutical Public-Private Partnerships: From Input to Impact. Pharmaceutical Research, 34(10), 1985-1999. https://doi.org/10.1007/s11095-017-2192-5
2016
Wetenschappelijke publicaties
Crommelin, D. J., Broich, K., Holloway, C., Meesen, B., Lizrova Preiningerova, J., Prugnaud, J.-L., & Silva-Lima, B. (2016). The regulator's perspective: How should new therapies and follow-on products for MS be clinically evaluated in the future? Multiple sclerosis (Houndmills, Basingstoke, England), 22(2 Suppl), 47-59. https://doi.org/10.1177/1352458516650744
Crommelin, D. J. A., & Bouwman-Boer, Y. (2016). Pharmacy preparations: Back in the limelight? Pharmacists make up your mind! International Journal of Pharmaceutics, 514(1), 11-14. https://doi.org/10.1016/j.ijpharm.2016.09.031
2014
Wetenschappelijke publicaties
Schellekens, H., Stegemann, S., Weinstein, V., de Vlieger, J. S. B., Flühmann, B., Mühlebach, S., Gaspar, R., Shah, V. P., & Crommelin, D. J. A. (2014). How to regulate nonbiological complex drugs (NBCD) and their follow-on versions: points to consider. The AAPS journal, 16(1), 15-21. https://doi.org/10.1208/s12248-013-9533-z
Crommelin, D. J. A., de Vlieger, J. S. B., Weinstein, V., Mühlebach, S., Shah, V. P., & Schellekens, H. (2014). Different pharmaceutical products need similar terminology. The AAPS journal, 16(1), 11-4. https://doi.org/10.1208/s12248-013-9532-0
2013
Wetenschappelijke publicaties
Teunissen, E., Mastrobattista, E., Rottier, P., & Crommelin, D. (2013). Directed evolution of artificial viruses. Molecular Diagnosis and Therapy, 21(9), 18-19. https://doi.org/10.1038/mt.2013.140
Crommelin, D. J. A., & Florence, A. T. (2013). Towards more effective advanced drug delivery systems. International Journal of Pharmaceutics, 454, 496-511.
2012
Wetenschappelijke publicaties
Ghassemi, A. H., Van Steenbergen, M. J., Barendregt, A., Talsma, H., Kok, R. J., Van Nostrum, C. F., Crommelin, D. J. A., & Hennink, W. E. (2012). Controlled release of octreotide and assessment of peptide acylation from poly(D,L-lactide-co-hydroxymethyl glycolide) compared to PLGA microspheres. Pharmaceutical Research, 29(1), 110-120. https://doi.org/10.1007/s11095-011-0517-3
Denee, T. R., Sneekes, A., Stolk, P., Juliens, A., Raaijmakers, J. A. M., Goldman, M., Crommelin, D. J. A., & Janssen, J. W. (2012). Measuring the value of public-private partnerships in the pharmaceutical sciences. Nature Reviews. Drug Discovery, 11(5), 419.
Luijten, P. R., van Dongen, G. A., Moonen, C. T. W., Storm, G., & Crommelin, D. J. A. (2012). Public-private partnerships in translational medicine: Concepts and practical examples. Journal of Controlled Release, 161(2), 416-421. http://www.ncbi.nlm.nih.gov/pubmed/22465390
Jiskoot, W., Randolph, T. W., Volkin, D. B., Middaugh, C. R., Schoneich, C., Winter, G., Friess, W., Crommelin, D. J. A., & Carpenter, J. F. (2012). Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release. Journal of Pharmaceutical Sciences, 101(3), 946-54.
Rowland, M., Noe, C. R., Smith, D. A., Tucker, G. T., Crommelin, D. J. A., Peck, C. C., R occi ML, J. R., Besancon, L., & Shah, V. P. (2012). Impact of the pharmaceutical sciences on health care: a reflection over the past 50 years. Journal of Pharmaceutical Sciences, 101(11), 4075-99.
2011
Wetenschappelijke publicaties
Amidi, M., de Raad, M., Crommelin, D. J. A., Hennink, W. E., & Mastrobattista, E. (2011). Antigen-expressing immunostimulatory liposomes as a genetically programmable synthetic vaccine. Syst Synth Biol, 5(1-2), 21-31.
Schellekens, H., Klinger, E., Muehlebach, S., Brin, J.-F., Storm, G., & Crommelin, D. J. A. (2011). The therapeutic equivalence of complex drugs. Regulatory Toxicology and Pharmacology, 59(1), 176-183. https://doi.org/10.1016/j.yrtph.2010.09.021
Chen, M. L., Shah, V. P., Crommelin, D. J. A., Shargel, L., Bashaw, D., Bhatti, M., Blume, H., Dressman, J., Ducharme, M., Fackler, P., Hyslop, T., Lutter, L., Morais, J., Ormsby, E., Thomas, S., Tsang, Y. C., Velagapudi, R., & Yu, L. X. (2011). Harmonization of regulatory approaches for evaluating therapeutic equivalence and interchangeability of multisource drug products: workshop summary report. The AAPS journal, 13, 556-564.
van Gaal, E. V. B., van Eijk, R., Oosting, R. S., Kok, R. J., Hennink, W. E., Crommelin, D. J. A., & Mastrobattista, E. (2011). How to screen non-viral gene delivery systems in vitro? Journal of Controlled Release, 154(3), 218-32.
van Gaal, E. V. B., Oosting, R. S., van Eijk, R., Bakowska, M., Feyen, D., Kok, R. J., Hennink, W. E., Crommelin, D. J. A., & Mastrobattista, E. (2011). DNA nuclear targeting sequences for non-viral gene delivery. Pharmaceutical Research, 28(7), 1707-22.
van de Briel, R., Cransveld, C. C., Crommelin, D. J. A., Diamant, Z., Glazenburg, B., Joos, G., Kuper, F., Natsch, A., Nijkamp, F. P., Noteborn, H., Pieters, R. J., Roberts, D., Roggen, E., Rorije, E., van den Heuvel, R., Engelen, J., Verstaelen, S., & van Loveren, H. (2011). Respiratory sensitization: advances in assessing the risk of respiratory inflammation and irritation. Toxicology in Vitro, 25(7), 1251-1258. https://doi.org/10.1016/j.tiv.2011.04.027
2010
Wetenschappelijke publicaties
Ghassemi, A. H., van Steenbergen, M. J., Talsma, H., van Nostrum, C. F., Jiskoot, W., Crommelin, D. J., & Hennink, W. E. (2010). Microspheres of hydrophilic PLGA highly attractive for protein delivery. Journal of controlled release : official journal of the Controlled Release Society, 148(1).
Ghassemi, A. H., Van Steenbergen, M. J., Talsma, H., Van Nostrum, C. F., Jiskoot, W., Crommelin, D. J. A., & Hennink, W. E. (2010). Microspheres of hydrophilic PLGA highly atractive for protein delivery. Journal of Controlled Release, 148(1), 39-40. https://doi.org/10.1016/j.jconrel.2010.07.047
Ghassemi, A. H., van Steenbergen, M. J., Talsma, H., van Nostrum, C. F., Crommelin, D. J. A., & Hennink, W. E. (2010). Hydrophilic polyester microspheres: effect of molecular weight and copolymer composition on release of BSA. Pharmaceutical Research, 27(9), 2008-17.
Crommelin, D. J. A., Stolk, P., Besancon, L. J. R., Shah, V. P., Midha, K., & Leufkens, H. G. M. (2010). Pharmaceutical Sciences in 2010. Nature Reviews. Drug Discovery, 9, 99-100.
Amidi, M., de Raad, M., de Graauw, H., van Ditmarsch, D., Hennink, W. E., Crommelin, D. J. A., & Mastrobattista, E. (2010). Optimization and quantification of protein synthesis inside liposomes. Journal of Liposome Research, 20(1), 73-83.
Carpenter, J. F., Randolph, T. W., Jiskoot, W., Crommelin, D. J. A., Middaugh, C. R., & Winter, G. (2010). Potential Inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: essential need to use orthogonal methods to assure the quality of therapeutic protein products. Journal of Pharmaceutical Sciences, 99, 2000-2009.
van Hell, A. J., Fretz, M. M., Crommelin, D. J. A., Hennink, W. E., & Mastrobattista, E. (2010). Peptide nanocarriers for intracellular delivery of photosensitizers. Journal of Controlled Release, 141(3), 347-53.
van Hell, A. J., Klymchenko, A., Burgers, P. P., Moret, E. E., Jiskoot, W., Hennink, W. E., Crommelin, D. J. A., & Mastrobattista, E. (2010). Conformation and intermolecular interactions of SA2 peptides self-assembled into vesicles. Journal of Physical Chemistry. B, 114(34), 11046-52. https://doi.org/10.1021/jp103440d
van Gaal, E. V. B., Oosting, R. S., Hennink, W. E., Crommelin, D. J. A., & Mastrobattista, E. (2010). Junk DNA enhances pEI-based non-viral gene delivery. International Journal of Pharmaceutics, 390(1), 76-83.
van Gaal, E. V. B., Spierenburg, G., Hennink, W. E., Crommelin, D. J. A., & Mastrobattista, E. (2010). Flow cytometry for rapid size determination and sorting of nucleic acid containing nanoparticles in biological fluids. Journal of Controlled Release, 141(3), 328-38.
Crommelin, D. J. A., Park, K., & Florence, A. (2010). Pharmaceutical Nanotechnology: Unmet needs in drug delivery. Journal of Controlled Release, 141, 36-263.
Shah, V. P., Besancon, L. J. R., Stolk, P., Tucker, G., & Crommelin, D. J. A. (2010). The pharmaceutical sciences in 2020: Report of a conference organized by the board of pharmaceutical sciences of the International Pharmaceutical Federation (FIP). Pharmaceutical Research, 27, 396-399.
2009
Wetenschappelijke publicaties
Ghassemi, A. H., van Steenbergen, M. J., Talsma, H., van Nostrum, C. F., Jiskoot, W., Crommelin, D. J. A., & Hennink, W. E. (2009). Preparation and characterization of protein loaded microspheres based on a hydroxylated aliphatic polyester, poly(lactic-co-hydroxymethyl glycolic acid). Journal of Controlled Release, 138(1), 57-63. https://doi.org/10.1016/j.jconrel.2009.04.025
Shah, V. P., Besanc, L. J. R., Stolk, P., Tucker, G., & Crommelin, D. J. A. (2009). The pharmaceutical sciences in 2020-Report of a conference organized by the Board of Pharmaceutical Sciences Federation (FIP). European Journal of Pharmaceutical Sciences, 38, 419-425.
Verpoorte, R., Crommelin, D. J. A., Danhof, M., Gilissen, L. J., Schuitmaker, H., van der Greef, H. J., & Witkamp, R. F. (2009). Commentary: “A systems view on the future of medicine: Inspiration from Chinese medicine?”. Journal of Ethnopharmacology, 121, 479-481.
Wilschut, K. J., van der Aa, M., Oosting, R. S., Hennink, W. E., Koning, G. A., Crommelin, D. J. A., & Mastrobattista, E. (2009). Fluorescence in situ hybridization to monitor the intracellular location and accessibility of plasmid DNA delivered by cationic polymer-based gene carriers. European Journal of Pharmaceutics and Biopharmaceutics, 72(2), 391-396.
Carpenter, J. F., Randolph, T. W., Jiskoot, W., Crommelin, D. J. A., Middaugh, C. R., Winter, G., Fan, Y. X., Kirshner, S., Verthelyi, D., Kozlowski, S., Clouse, K. A., Swann, P. G., Rosenberg, A., & Cherney, B. (2009). Overlooking Subvisible Particles in Therapeutic Protein Products: Gaps That May Compromise Product Quality. Journal of Pharmaceutical Sciences, 98(4), 1201-1205.
Vakpublicaties
Iyer, N. J., Janssen, J., Leurs, R., & Crommelin, D. J. A. (2009). Neglected no more: fostering innovation in the neglected diseases. In Preclinical Drug Development (pp. 62-65)
2008
Wetenschappelijke publicaties
Carstens, M. G., Van Nostrum, C. F., Verrijk, R., De Leede, L. G. J., Crommelin, D. J. A., & Hennink, W. E. (2008). A mechanistic study on the chemical and enzymatic degradation of PEG-Oligo(ε-caprolactone) micelles. Journal of Pharmaceutical Sciences, 97(1), 506-518. https://doi.org/10.1002/jps.21092
Amidi, M., Krudys, K. M., Snel, C. J., Crommelin, D. J. A., Della Pasqua, O. E., Hennink, W. E., & Jiskoot, W. (2008). Efficacy of pulmonary insulin delivery in diabetic rats: Use of a model-based approach in the evaluation of insulin powder formulations. Journal of Controlled Release, 127, 257-266.
Bouchard, A., Jovanovic, N., de Boer, A. H., Martin, A., Jiskoot, W., Crommelin, D. J. A., Hofland, G. W., & Witkamp, G. J. (2008). Effect of the spraying conditions and nozzle design on the shape and size distribution of particles obtained with supercritical fluid drying. European Journal of Pharmaceutics and Biopharmaceutics, 70, 389-401.
Bouchard, A., Jovanovic, N., Hofland, G. W., Jiskoot, W., Mendes, E., Crommelin, D. J. A., & Witkamp, G. J. (2008). Supercritical fluid drying of carbohydrates: Selection of suitable excipients and process conditions. European Journal of Pharmaceutics and Biopharmaceutics, 68, 781-794.
Crommelin, D. J. A., & Bjerrum, O. J. (2008). The EUFEPS Workshop on Institutional Peer Review “The Ultimate Tool to Advance the Pharmaceutical Sciences?”. European Journal of Pharmaceutical Sciences, 35, 361-364.
Carstens, M. G., van Nostrum, C. F., Verrijk, R., de Leede, L., Crommelin, D. J. A., & Hennink, W. E. (2008). A mechanistic study on the chemical and enzymatic degradation of PEG-oligo(-caprolactone) micelles. Journal of Pharmaceutical Sciences, 97, 506-518.
Amidi, M., Pelikaan, H. C., de Boer, A. H., Crommelin, D. J. A., Hennink, W. E., & Jiskoot, W. (2008). Preparation and physicochemical characterization of supercritically dried insulin-loaded microparticles for pulmonary delivery. European Journal of Pharmaceutics and Biopharmaceutics, 68, 191-200.
Jovanovic, N., Bouchard, A., Sutter, M., van Speybroeck, M., Hofland, G. W., Witkamp, G. J., Crommelin, D. J. A., & Jiskoot, W. (2008). Stable sugar-based protein formulations by supercritical fluid drying. International Journal of Pharmaceutics, 346, 102-108.
Carstens, M. G., de Jong, P. H. J. L. F., van Nostrum, C. F., Kemmink, J., Verrijk, R., de Leede, L., Crommelin, D. J. A., & Hennink, W. E. (2008). The effect of core composition in biodegradable oligomeric micelles as taxane formulations. European Journal of Pharmaceutics and Biopharmaceutics, 68, 596-606.
Jovanovic, N., Bouchard, A., Hofland, G. W., Witkamp, G. J., Crommelin, D. J. A., & Jiskoot, W. (2008). Stabilization of IgG by supercritical fluid drying: Optimization of formulation and process parameters. European Journal of Pharmaceutics and Biopharmaceutics, 68, 183-190.
Bouchard, A., Jovanovic, N., Martin, A., Hofland, G. W., Jiskoot, W., Crommelin, D. J. A., & Witkamp, G. J. (2008). Effect of the modifier on the particle formation and crystallization behaviour during precipitation from aqueous solutions. Journal of Supercritical Fluids, 44, 409-421.
Bouchard, A., Jovanovic, N., Hofland, G. W., Jiskoot, W., Crommelin, D. J. A., & Witkamp, G. J. (2008). Ways of manipulating the polymorphism of glycine during supercritical fluid crystallization. Journal of Supercritical Fluids, 44, 422-432.
2007
Wetenschappelijke publicaties
Metz, B., Jiskoot, W., Mekkes, D., Kingma, R., Hennink, W. E., Crommelin, D. J. A., & Kersten, G. F. A. (2007). Quality control of routine, experimental and real-time aged diphtheria toxoids by in vitro analytical techniques. Vaccine, 25(39-40), 6863-6871. https://doi.org/10.1016/j.vaccine.2007.07.009
Carstens, M. G., Bevernage, J. J. L., van Nostrum, C. F., van Steenbergen, M. J., Flesch, F. M., Verrijk, R., de Leede, L., Crommelin, D. J. A., & Hennink, W. E. (2007). Small oligomeric micelles based on end group modified mPeg-oligocaprolactone with monodisperse hydrophobic blocks. Macromolecules, 40, 116-122.
Vugt-Wensink, K. D. F., Meijer, Y. J., van Steenbergen, M. J., Verrijk, R., Jiskoot, W., Crommelin, D. J. A., & Hennink, W. E. (2007). Effect of excipients on the encapsulation efficiency and release of human growth hormone from dextran microspheres. European Journal of Pharmaceutics and Biopharmaceutics, 67, 589-596.
Amidi, M., Pellikaan, H., Hirschberg, H., de Boer, A. H., Crommelin, D. J. A., Hennink, W. E., Kersten, G. F. A., & Jiskoot, W. (2007). Diphtheria toxoid-containing microparticulate powder formulations for pulmonary vaccination: Preparation, characterization and evaluation in guinea pigs. Vaccine, 25, 6818-6829.
Vugt-Wensink, K. D. F., de Vrueh, R. L., Gresnigt, M. G., Hoogerbrugge, M., van Buul-Offers, S. C., de Leede, L., Sterkman, J. G. W., Crommelin, D. J. A., Hennink, W. E., & Verrijk, R. (2007). Preclinical and clinical in vitro in vivo correlation of an hGH dextran microsphere formulation. Pharmaceutical Research, 24, 2239-2248.
Bouchard, A., Jovanovic, N., Hofland, G. W., Mendes, E., Crommelin, D. J. A., Jiskoot, W., & Witkamp, G. J. (2007). Selective production of polymorphs and pseudomorphs using supercritical fluid crystallization from aqueous solutions. Crystal Growth & Design, 7, 1432-1440.
van der Aa, M. A. E. M., Huth, U. S., Häfele, S. Y., Schubert, R., Oosting, R. S., Mastrobattista, E., Hennink, W. E., Peschka-Süss, R., Koning, G. A., & Crommelin, D. J. A. (2007). Cellular uptake of cationic polymer-DNA complexes via caveolae plays a pivotal role in gene transfection in COS-7 cells. Pharmaceutical Research, 24, 1590-1598.
https://dspace.library.uu.nl/bitstream/handle/1874/31094/Cellular%2520uptake.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/31094/Cellular%2520uptake.pdf?sequence=1
Amidi, M., Romijn, S., Verhoef, J. C., Junginger, H. E., Bungener, L., Huckriede, A., Crommelin, D. J. A., & Jiskoot, W. (2007). N-trimethyl chitosan (TMC) nanoparticles loaded with influenza subunit antigen for intranasal vaccination: biological properties and immunogenicity in a mouse model. Vaccine, 25, 144-153.
Bouchard, A., Jovanovic, N., Jiskoot, W., Mendesd, E., Witkamp, G. J., Crommelin, D. J. A., & Hofland, G. W. (2007). Lysozyme particle formation during supercritical fluid drying: Particle morphology and molecular integrity. Journal of Supercritical Fluids, 40, 293-307.
van Hell, A. J., Costa, C. I. C. A., Flesch, F. M., Sutter, M., Jiskoot, W., Crommelin, D. J. A., Hennink, W. E., & Mastrobattista, E. (2007). Self-assembly of recombinant amphiphilic oligopeptides into vesicles. Biomacromolecules, 8, 2753-2761.
Vakpublicaties
Schellekens, H., Crommelin, D. J. A., & Jiskoot, W. (2007). Immunogenicity of antibody therapeutics. In S. Dübel (Ed.), Handbook of Therapeutic Antibodies (pp. 267-276). Wiley.
Schellekens, H., Jiskoot, W., & Crommelin, D. J. A. (2007). Biosimilars. In S. C. Gad (Ed.), Handbook of Pharmaceutical Biotechnology (pp. 1453-1461). Wiley.
Crommelin, D. J. A., Sindelar, R. D., & Meibohm, B. (2007). Pharmaceutical Biotechnology, An Introduction for Pharmacists and Pharmaceutical Scientists. Informa Healthcare.
Hermeling, S., Crommelin, D. J. A., Schellekens, H., & Jiskoot, W. (2007). Immunogenicity of therapeutic proteins. In S. C. Gad (Ed.), Handbook of Pharmaceutical Biotechnology (pp. 815-833). Wiley.
Crommelin, D. J. A. (2007). Formulation of Biotech Products, including Biopharmaceutical Considerations. In D. J. A. Crommelin, R. D. Sindelar, & B. Meibohm (Eds.), Pharmaceutical Biotechnology, An Introduction for Pharmacists and Pharmaceutical Scientists (pp. 67-93). Informa Healthcare.
Shah, V. P., & Crommelin, D. J. A. (2007). Regulatory Issues and Drug Product Approval for Biopharmaceuticals. In Pharmaceutical Biotechnology, An Introduction for Pharmacists and Pharmaceutical Scientists (pp. 447-453). Informa Healthcare.
2006
Wetenschappelijke publicaties
Hermeling, S., Crommelin, D. J. A., Schellekens, H., & Jiskoot, W. (2006). Immunogenicity of Therapeutic Proteins. In Handbook of Pharmaceutical Biotechnology (pp. 815-833). Wiley. https://doi.org/10.1002/9780470117118.ch06d
Carstens, M. G., van Nostrum, C. F., Ramzi, A., de Leede, L. G., Crommelin, D. J., & Hennink, W. E. (2006). Self-assembly of PEG-oligolactates with monodisperse hydrophobic blocks. Journal of controlled release : official journal of the Controlled Release Society, 116(2). https://doi.org/10.1016/j.jconrel.2006.09.039
Vugt-Wensink, K. D. F., Vlugt, T. J. H., Jiskoot, W., Crommelin, D. J. A., Verrijk, R., & Hennink, W. E. (2006). Modeling the release of proteins from degrading crosslinked dextran microspheres using kinetic Monte Carlo simulations. Journal of Controlled Release, 111, 117-127.
Hermeling, S., Jiskoot, W., Crommelin, D. J. A., & Schellekens, H. (2006). Reaction to the paper: interaction of polysorbate 80 with erythropoietin: a case study in protein-surfactant interactions. Pharmaceutical Research, 23, 641-642.
Vlugt-Wensink, K. D. F., Jiang, X., Schotman, G., Kruijtzer, G., Vredenberg, A., Chung, J. T., Zhang, Z., Versluis, C., Ramos, D., Verrijk, R., Jiskoot, W., Crommelin, D. J. A., & Hennink, W. E. (2006). In vitro degradation behavior of microspheres based on cross-linked dextran. Biomacromolecules, 7(11), 2983-2990.
https://dspace.library.uu.nl/bitstream/handle/1874/19759/26_in%2520vitro.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/19759/26_in%2520vitro.pdf?sequence=1
Metz, B., Kersten, G. F. A., Baart, G. J. E., de Jong, A., Meiring, H. D., ten Hove, J., van Steenbergen, M. J., Hennink, W. E., Crommelin, D. J. A., & Jiskoot, W. (2006). Identification of formaldehyde-induced modifications in proteins: reactions with insulin. Bioconjugate Chemistry, 17, 815-822.
Jovanovic, N., Bouchard, A., Hofland, G. W., Witkamp, G. J., Crommelin, D. J. A., & Jiskoot, W. (2006). Distinct effects of sucrose and trehalose on protein stability during supercritical fluid drying and freeze-drying. European Journal of Pharmaceutical Sciences, 27, 336-345.
van der Aa, M. A. E. M., Mastrobattista, E., Oosting, R. S., Hennink, W. E., Koning, G. A., & Crommelin, D. J. A. (2006). The nuclear pore complex: the gateway to successful nonviral gene delivery. Pharmaceutical Research, 23(3), 447-459.
https://dspace.library.uu.nl/bitstream/handle/1874/19728/oosting_06_nuclearporecomplex.pdf?sequence=2
https://dspace.library.uu.nl/bitstream/handle/1874/19728/oosting_06_nuclearporecomplex.pdf?sequence=2
Hermeling, S., Schellekens, H., Maas, M., Gebbink, M. F. B. G., Crommelin, D. J. A., & Jiskoot, W. (2006). Antibody response to aggregated human interferon Alpha 2b wild-type and transgenic immune tolerant mice depends on type and level of aggregation. Journal of Pharmaceutical Sciences, 95, 1084-1095.
Mastrobattista, E., van der Aa, M. A. E. M., Hennink, W. E., & Crommelin, D. J. A. (2006). Artificial viruses: a nanotechnological approach to gene delivery. Nature Reviews. Drug Discovery, 5, 115-121.
Vlugt-Wensink, K. D. F., Vlugt, T. J. H., Jiskoot, W., Crommelin, D. J. A., Verrijk, R., & Hennink, W. E. (2006). Modelling the release of proteins from degrading dextran microspheres using kinetic Monte Carlo simulations. Journal of Controlled Release, 111, 117-127.
https://dspace.library.uu.nl/bitstream/handle/1874/19760/2006-031.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/19760/2006-031.pdf?sequence=1
van Gaal, E. V. B., Hennink, W. E., Crommelin, D. J. A., & Mastrobattista, E. (2006). Plasmid engineering for controlled and sustained gene expression for nonviral gene therapy. Pharmaceutical Research, 23, 1053-1074.
Vakpublicaties
Crommelin, D. J. A., & Zuidam, N. J. (2006). Hydrolysis of phospholipids in liposomes and stability-indicating analytical techniques. In G. Gregoriadis (Ed.), Liposome Technology (pp. 285-294)
Schiffelers, R. M., Crommelin, D. J. A., & Storm, G. (2006). Chapter 7: Silencing proteins. In V. Torchilin (Ed.), Delivery of Protein and Peptide Drugs in Cancer (pp. 127-143). Imperial College Press.
2005
Wetenschappelijke publicaties
Mastrobattista, E., Bravo, S. A., van der Aa, M., & Crommelin, D. J. A. (2005). Nonviral gene delivery systems: From simple transfection agents to artificial viruses. Drug Discovery Today: Technologies, 2(1), 103-109. https://doi.org/10.1016/j.ddtec.2005.04.002
Funhoff, A. M., van Nostrum, C. F., Lok, M. C., Kruijtzer, J. A. W., Crommelin, D. J. A., & Hennink, W. E. (2005). Cationic polymethacrylates with covalently linked membrane destabilizing peptides as gene delivery vectors. Journal of Controlled Release, 101(1-3), 233-246.
Zhao, Y., Benita, Y., Lok, M., Kuipers, B., van der Ley, P., Jiskoot, W., Hennink, W. E., Crommelin, D. J. A., & Oosting, R. S. (2005). Multi-antigen immunization using IgG binding domain ZZ as carrier. Vaccine, 23, 5082-5090.
van der Aa, M. A. E. M., Koning, G. A., d'Oliveira, C., Oosting, R. S., Wilschut, K. J., Hennink, W. E., & Crommelin, D. J. A. (2005). An NLS peptide covalently linked to linear DNA does not enhance transfection efficiency of cationic polymer based gene delivery systems. Journal of Gene Medicine, 7, 208-217.
Visser, C. C., Stevanovic, S., Voorwinden, L. H., van Bloois, L., Gaillard, P. J., Danhof, M., Crommelin, D. J. A., & de Boer, A. G. (2005). Targeting liposomes with protein drugs to the blood-brain barrier in vitro. European Journal of Pharmaceutical Sciences, 25(2-3), 299-305.
Mastrobattista, E., Bravo, S. A., van der Aa, M. A. E. M., & Crommelin, D. J. A. (2005). Nonviral gene delivery systems: from simple transfection agents to artifical viruses. Drug Discovery Today. Technologies, 2, 103-109.
Carstens, M. G., van Nostrum, C. F., Ramzi, A., Meeldijk, J. D., Verrijk, R., de Leede, L. L., Crommelin, D. J. A., & Hennink, W. E. (2005). Poly(ethylene glycol)-oligolactates with monodisperse hydrophobic blocks: Preparation, characterization, and behavior in water. Langmuir, 21(24), 11446-11454.
Hermeling, S., Jiskoot, W., Crommelin, D. J. A., Bornaes, C., & Schellekens, H. (2005). Development of a transgenic mouse model immune tolerant for human interferon beta. Pharmaceutical Research, 22(6), 847-851.
Funhoff, A. M., Monge, S., Teeuwen, R., Koning, G. A., Schuurmans-Nieuwenbroek, N. M. E., Crommelin, D. J. A., Haddleton, D. M., Hennink, W. E., & van Nostrum, C. F. (2005). PEG shielded polymeric double-layered micelles for gene delivery. Journal of Controlled Release, 102(3), 711-724.
Hermeling, S., Aranha, L. J., Damen, M., Slijper, M., Schellekens, H., Crommelin, D. J. A., & Jiskoot, W. (2005). Structural characterization and immunogenicity in wild-type and immune tolerant mice of degraded recombinant human interferon alpha2b. Pharmaceutical Research, 22, 1997-2006.
Arigita, C., Luijkx, T., Jiskoot, W., Poelen, M., Hennink, W. E., Crommelin, D. J. A., van der Ley, P., van Els, C., & Kersten, G. F. A. (2005). Well-defined and potent liposomal meningococcal B vaccines adjuvated with LPS derivatives. Vaccine, 23(43), 5091-5098.
Vakpublicaties
Jiskoot, W., & Crommelin, D. J. A. (2005). Methods for Structural Analysis of Protein Pharmaceuticals. AAPS Press.
Verbaan, F. J., Crommelin, D. J. A., Hennink, W. E., & Storm, G. (2005). Poly(2-(dimethylamino)ethyl methacrylate)-based polymers for the delivery of genes in vitro and in vivo. In M. M. Amiji (Ed.), Polymeric gene delivery. Principles and applications (pp. 107-132). CRC Press.
Hennink, W. E., van Nostrum, C. F., Crommelin, D. J. A., & Bezemer, J. Z. (2005). Hydrogels for the controlled release of proteins. In G. S. Kwon (Ed.), Polymeric Drug Delivery Systems Taylor & Francis.
Overige resultaten
de Koning, G., van der Gugten, J., Oliveira, S., Oosting, R. S., Hennink, W. E., Crommelin, D. J. A., & van der Aa, M. A. E. M. (2005). Covalent attachment of an NLS-peptide to linear dna does not enhance transfection efficiency of cationic polymer based gene delivery systems. Journal of Controlled Release, 101(1-3), 395-7.
2004
Wetenschappelijke publicaties
Bos, G. W., Kanellos, T., Crommelin, D. J. A., Hennink, W. E., & Howard, C. R. (2004). Cationic polymers that enhance the performance of HbsAg DNA in vivo. Vaccine, 23(4), 460-469. https://doi.org/10.1016/j.vaccine.2004.06.020
Visser, C. C., Voorwinden, H. L., van Bloois, L., Hardens, L. R., Eloualid, M., Crommelin, D. J. A., Danhof, M., & de Boer, A. C. (2004). Coupling of metal containing homing devices to liposomes via a maleimide linker: use of TCEP to stabilize thiol-groups without scavenging metals. Journal of Drug Targeting, 12, 569-573.
Arigita, C., van den Berg, J., Wensink, K. D. F., van Steenbergen, M. J., Hennink, W. E., Crommelin, D. J. A., Kersten, G. F. A., & Jiskoot, W. (2004). Immunogenicity of meningococcal PorA formulations encapsulated in biodegradable microspheres. European Journal of Pharmaceutical Sciences, 21, 131-141.
Verbaan, F. J., Crommelin, D. J. A., Hennink, W. E., & Storm, G. (2004). Poly (2-dimethylamino)ethyl methacrylate)-based polymers for the delivery of genes in vitro and in vivo. In M. M. Maiji (Ed.), Polymeric Gene Delivery (pp. 107-132). CRC Press.
Jovanovic, N., Bouchard, A., Hofland, G. W., Witkamp, G. J., Crommelin, D. J. A., & Jiskoot, W. (2004). Stabilization of proteins in dry powder formulations using supercritical fluid technology. Pharmaceutical Research, 21, 1955-1969.
Funhoff, A. M., van Nostrum, C. F., Koning, G. A., Schuurmans-Nieuwenbroek, N. M. E., Crommelin, D. J. A., & Hennink, W. E. (2004). Endosomal escape of polymeric gene delivery complexes is not always enhanced by polymers buffering at low pH. Biomacromolecules, 5, 32-39.
Verbaan, F. J., Oussoren, C., Snel, C. J., Crommelin, D. J. A., Hennink, W. E., & Storm, G. (2004). Steric stabilization of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes mediates prolonged circulation and tumor targeting in mice. Journal of Gene Medicine, 6, 64-75.
Arigita, C., Jiskoot, W., Wetsdijk, J., van Ingen, C., Hennink, W. E., Crommelin, D. J. A., & Kersten, G. F. A. (2004). Stability of mono- and trivalent menigococcal outer membrane vesicle vaccines. Vaccine, 22, 629-642.
Homhuan, A., Prakongpan, S., Poomvises, P., Maas, R. A., Crommelin, D. J. A., Kersten, G. F. A., & Jiskoot, W. (2004). Virosome and ISCOM vaccines against Newcastle disease: preparation, characterization and immunogenicity. European Journal of Pharmaceutical Sciences, 22, 459-468.
Funhoff, A. M., van Nostrum, C. F., Lok, M. C., Fretz, M. M., Crommelin, D. J. A., & Hennink, W. E. (2004). Poly(3-guanidinopropyl methacrylate): a novel cationic polymer for gene delivery. Bioconjugate Chemistry, 15, 1212-1220.
Visser, C. C., Voorwinden, H. L., Crommelin, D. J. A., Danhof, M., & de Boer, A. G. (2004). Characterization and modulation of the transferrin receptor on brain capillary endothelial cells. Pharmaceutical Research, 21, 761-769.
Burgess, D. J., Crommelin, D. J. A., Hussain, A. S., & Chen, M. L. (2004). Assuring quality and performance of sustained and controlled release parenterals. European Journal of Pharmaceutical Sciences, 21, 679-690.
Visser, C. C., Stevanovic, S., Voorwinden, H. L., Gaillard, P. J., Crommelin, D. J. A., Danhof, M., & de Boer, A. G. (2004). Validation of the transferrin receptor for drug targeting to brain capillary endothelial cells in vitro. Journal of Drug Targeting, 12, 145-150.
Hermeling, S., Crommelin, D. J. A., Schellekens, H., & Jiskoot, W. (2004). Structure-immunogenicity relationships of therapeutic proteins. Pharmaceutical Research, 21, 897-903.
Funhoff, A. M., van Nostrum, C. F., Janssen, A. P. C. A., Fens, M. H. A. M., Crommelin, D. J. A., & Hennink, W. E. (2004). Polymer side-chain degradation as a tool to control the destabilization of polyplexes. Pharmaceutical Research, 21, 170-176.
Metz, B., Kersten, G. F. A., Hoogerhout, P., Timmermans, H. A. M., de Jong, A., Meiring, H. D., ten Hove, J., Hennink, W. E., Crommelin, D. J. A., & Jiskoot, W. (2004). Identification of formaldehyde-induced modifications in proteins. Reactions with model peptides. Journal of Biological Chemistry, 279, 6235-6243.
Vakpublicaties
Homhuan, A., Pathanasophon, P., Crommelin, D. J. A., Jiskoot, W., Kersten, G. F. A., & Prakongpan, S. (2004). Characterization and protection in mice of outer membrane proteins from pasteurella multocida A: 1 incorporated in lipid vaccine delivery systems. Science Asia, 30, 231-237.
Crommelin, D. J. A. (2004). Delivery of biologicals: the wish list is long.... Expert Opinion on Drug Delivery, 1, 3-5.
2003
Wetenschappelijke publicaties
van Steenis, J. H., Maarseveen, E. M., Verbaan, F. J., Verrijk, R., Crommelin, D. J. A., Storm, G., & Hennink, W. E. (2003). Preparation and characterization of folate-targeted pEG-coated pDMAEMA-based polyplexes. Journal of Controlled Release, 87(1-3), 167-176. https://doi.org/10.1016/S0168-3659(02)00361-9
Arigita, C., Kersten, G. F. A., Hazendonk, T., Hennink, W. E., Crommelin, D. J. A., & Jiskoot, W. (2003). Restored functional immunogenicity of purified meningococcal PorA by incorporation into liposomes. Vaccine, 21, 950-960.
Arigita, C., Bevaart, L., Everse, L. A., Koning, G. A., Hennink, W. E., Crommelin, D. J. A., van de Winkel, J. G. J., van Vugt, M. J., Kersten, G. F. A., & Jiskoot, W. (2003). Liposomal meningococcal B vaccination: Role of dendritic cell targeting in the development of a protective immune response. Infection and Immunity, 71(9), 5210-5218.
Metz, B., Jiskoot, W., Hennink, W. E., Crommelin, D. J. A., & Kersten, G. F. A. (2003). Physicochemical and immunochemical techniques predict the quality of diphtheria toxoid vaccines. Vaccine, 22(I12), 156-167.
Crommelin, D. J. A., & Storm, G. (2003). Liposomes: From the bench to the bed. Journal of Liposome Research, 13, 33-36.
Schellekens, H., & Crommelin, D. J. A. (2003). Equivocal role of micelles in Eprex adverse events. Nature Biotechnology, 21, 1265-1265.
Luten, J., van Steenis, J. H., van Someren, R., Kemmink, J., Schuurmans-Nieuwenbroek, N. M. E., Koning, G. A., Crommelin, D. J. A., van Nostrum, C. F., & Hennink, W. E. (2003). Water-soluble biodegradable cationic polyphosphazenes for gene delivery. Journal of Controlled Release, 89, 483-497.
Kersten, G. F. A., & Crommelin, D. J. A. (2003). Liposomes and ISCOMs. Vaccine, 21, 915-920.
Hermeling, S., Schellekens, H., Crommelin, D. J. A., & Jiskoot, W. (2003). Micelle-Associated Protein in Epoetin Formulations: A Risk Factor for Immunogenicity ? Pharmaceutical Research, 20, 1903-1908.
Crommelin, D. J. A., Storm, G., Verrijk, R., de Leede, L., Jiskoot, W., & Hennink, W. E. (2003). Shifting paradigms: biopharmaceuticals versus low molecular weight drugs. International Journal of Pharmaceutics, 266, 3-16.
Crommelin, D. J. A., Storm, G., Jiskoot, W., Stenekes, R. J. H., Mastrobattista, E., & Hennink, W. E. (2003). Nanotechnological approaches for the delivery of macromolecules. Journal of Controlled Release, 87, 81-88.
2002
Wetenschappelijke publicaties
van de Weert, M., van Steenbergen, M. J., Cleland, J. L., Heller, J., Hennink, W. E., & Crommelin, D. J. A. (2002). Semisolid, self-catalyzed poly(ortho ester)s as controlled-release systems: protein release and protein stability issues. Journal of Pharmaceutical Sciences, 91, 1065-1074.
van de Weert, M., van Dijkhuizen-Radersma, R., Bezemer, J., Hennink, W. E., & Crommelin, D. J. A. (2002). Reversible aggregation of lysozyme in a biodegradable amphiphilic multiblock copolymer. European Journal of Pharmaceutics and Biopharmaceutics, 54, 89-93.
Vernooij, E. A. A. M., Brouwers, J. F. H. M., Kettenes-van den Bosch, J. J., & Crommelin, D. J. A. (2002). HP-HPLC/ESI MS determination of acyl chain positions in phospholipids. Journal of Separation Science, 25, 285-289.
Mastrobattista, E., Crommelin, D. J. A., Wilschut, J., & Storm, G. (2002). Targeted liposomes for delivery of protein-based drugs into the cytoplasm of tumor cells. Journal of Liposome Research, 12, 57-65.
Vernooij, E. A. A. M., Kettenes-van den Bosch, J. J., Underberg, W. J. M., & Crommelin, D. J. A. (2002). Chemical hydrolysis of DOTAP and DOPE in a liposomal environment. Journal of Controlled Release, 79, 299-303.
Vernooij, E. A. A. M., Kettenes-van den Bosch, J. J., & Crommelin, D. J. A. (2002). Fourier transform infrared spectroscopic determination of the hydrolysis of poly(ethylene glycol)-phosphatidylethanolamine-containing liposomes. Langmuir, 18, 3466-3470.
Corvo, M. L., Jorge, J. C. S., van 't Hof, R., Cruz, M. E., Crommelin, D. J. A., & Storm, G. (2002). Superoxide dismutase entrapped in long-circulating liposomes: formulation design and therapeutic activity in rat adjuvant arthritis. Biochimica et Biophysica Acta-Biomembranes, 1564, 227-236.
Vernooij, E. A. A. M., Brouwers, J. F. H. M., Kettenes-van den Bosch, J. J., & Crommelin, D. J. A. (2002). RP-HPLC/ESI MS determination of acyl chain positions in phospholipids. Journal of Separation Science, 25, 285-289.
Vakpublicaties
Bos, G. W., Verrijk, R., Hennink, W. E., & Crommelin, D. J. A. (2002). Controlled release of pharmaceutical proteins from hydrogels. European biopharmaceutical review, Autumn, 94-101.
Crommelin, D. J. A., Bos, G. W., & Storm, G. (2002). Liposomes - succesful carrier systems for targeted drug delivery. Drug delivery parnerships news, 2(101).
2001
Wetenschappelijke publicaties
Bos, G. W., Verrijk, R., Franssen, O., Bezemer, J. M., Hennink, W. E., & Crommelin, D. J. A. (2001). Hydrogels for the controlled release of pharmaceutical proteins. Pharmaceutical Technology, 25(10), 110-120.
Bos, G. W., Crommelin, D. J. A., Hennink, W. E., Verrijk, R., Franssen, O., & Bezemer, J. M. (2001). Hydrogels for the controlled release of pharmaceutical proteins. Pharmaceutical Technology Europe, 13(11).
Mastrobattista, E., Schoen, P., Wilschut, J., Crommelin, D. J. A., & Storm, G. (2001). Targeting influenza virosomes to ovarian carcinoma cells. FEBS Letters, 509(1), 71-76. https://doi.org/10.1016/S0014-5793(01)03112-X
van Slooten, M. L., Boerman, O. C., Romoren, K., Kedar, E., Crommelin, D. J. A., & Storm, G. (2001). Liposomes as sustained release system for human interferon-gamma: biopharmaceutical ascpects. Biochimica et Biophysica Acta-General Subjects, 1530, 134-145.
Crommelin, D. J. A., Hennink, W. E., & Storm, G. (2001). Drug targeting systems: fundamental and applications to parenteral drug delivery. In A. M. Hillery, A. W. Lloyd, & J. Swarbick (Eds.), Drug delivery and applications to parenteral drug delivery (pp. 117-144)
Hennink, W. E., Cherng, J.-Y., Jiskoot, W., Talsma, H., & Crommelin, D. J. A. (2001). Pharmaceutical aspects of polymer-based non-viral gene delivery systems: experience with p(DMAEMA)-pCMV-lacZ polyplexes. STP pharma sciences, 11, 11-19.
Mastrobattista, E., Schoen, P., Wilschut, J., Crommelin, D. J. A., & Storm, G. (2001). Targeting influenza vitrosomes to ovarian carcinoma cells. FEBS Letters, 509, 71-76.
Verbaan, F. J., Oussoren, C., van Dam, I., Takakura, Y., Hashida, M., Crommelin, D. J. A., Hennink, W. E., & Storm, G. (2001). The fate of poly(2-dimethyl amino ethyl)methacrylate-based polyplexes after intravenous administration. International Journal of Pharmaceutics, 214, 99-101.
Bos, G. W., Verrijk, R., Franssen, O., Bezemer, J., Hennink, W. E., & Crommelin, D. J. A. (2001). Hydrogels for the controlled release of pharmaceutical proteins. Biopharm Europe, 13, 64-74.
Hennink, W. E., van de Wetering, P., Storm, G., & Crommelin, D. J. A. (2001). Gene delivery with water-soluble cationic methacrylate/methacrylamide polymers. In H. de Ruiter (Ed.), Proceedings of the 6th International Symposium on Adjuvants for Agrochemicals (pp. 595-607)
Mollee, H. M., Steenvoorden, D. P. T., de Vringer, T., & Crommelin, D. J. A. (2001). The infuence of the incorporation of cholesterol and water on the particle size, bilayer thickness, melting behavior, and relative sucrose ester composition of reversed vesicles. Journal of Pharmaceutical Sciences, 90, 586-596.
Crommelin, D. J. A., & Mekking, A. (2001). Formulering en toediening van farmaceutische eiwitten. In H. Schellekens, P. H. van Bragt, W. Olijve, & C. N. van der Weele (Eds.), Medische Biotechnologie (pp. 307-324). Elsevier gezondheid.
Crommelin, D. J. A., & Luessen, H. (2001). Drug delivery - optimizing efficacy, safety and convenience. In Pathways The Novartis Journal (pp. 46-50). (2).
Bos, G. W., Crommelin, D. J. A., & Hennink, W. E. (2001). Water-soluble cationic methacrylate polymers for nonviral gene delivery. In Methods of Molecular Medicine (pp. 35-60). (65).
Bos, G. W., & Crommelin, D. J. A. (2001). Design, production and regulatory approval of gene therapeutics. In Technology and Services (pp. 1-5)
Storm, G., Mastrobattista, E., Verbaan, F. J., Crommelin, D. J. A., & Hennink, W. E. (2001). Design of methacrylate-based polyplexes for tumor targeting. Gene Therapy, 6, 143-148.
Mastrobattista, E., Kapel, R. H. G., Eggenhuisen, M. H., Roholl, P. J. M., Crommelin, D. J. A., Hennink, W. E., & Storm, G. (2001). Lipid-coated polyplexes for targeted gene delivery to ovarian carcinoma cells. Cancer Gene Therapy, 8, 405-413.
van de Weert, M., Haris, P. I., Hennink, W. E., & Crommelin, D. J. A. (2001). Fourtier transform infrared spectrometric analysis of protein conformation: effect of the sampling method and stress factors. Analytical Biochemistry, 297, 160-169.
Bos, G. W., Verrijk, R., Franssen, O., Bezemer, J., Hennink, W. E., & Crommelin, D. J. A. (2001). Hydrogels for the controlled release of pharmaceutical proteins. Pharmaceutical Development and Technology, 25, 110-120.
Vakpublicaties
Stenekes, R. J. H., Loebis, A. E., Fernandes, C. M., Crommelin, D. J. A., & Hennink, W. E. (2001). Degradable dextran microspheres for the controlled release of liposomes. International Journal of Pharmaceutics, 214, 17-20.
Crommelin, D. J. A., Luessen, H., & Verrijk, R. (2001). Formulation of Pharmaceutical proteins - What are the rules of the game? Pharmaceutical manufactory and packing sourcer, 14-19.
2000
Wetenschappelijke publicaties
van, R. AJ., Taams, LS., Grosfeld-Stulemeyer, MC., van, E. W., Crommelin, DJ., & Wauben, MH. (2000). Induction of T cell anergy by liposomes with incorporated major histocompatibility complex (MHC) II/peptide complexes. Pharmaceutical Research. https://doi.org/10.1023/a:1007586400631
Zuidam, N. J., Posthuma, G., De Vries, E. T. J., Crommelin, D. J. A., Hennink, W. E., & Storm, G. (2000). Effects of physicochemical characteristics of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes on cellular association and internalization. Journal of Drug Targeting, 8(1), 51-66. https://doi.org/10.3109/10611860009009209
Bos, G. W., Trullas-Jimeno, A., Jiskoot, W., Crommelin, D. J. A., & Hennink, W. E. (2000). Sterilization of poly(dimethylamino) ethyl methacrylate-based gene transfer complexes. International Journal of Pharmaceutics, 211(1-2), 79-88. https://doi.org/10.1016/S0378-5173(00)00593-7
van Rensen, A. J. M. L., Taams, L. S., Grosfeld-Stulemeyer, M. C., van Eden, W., Crommelin, D. J. A., & Wauben, M. H. M. (2000). Induction of T cell anergy by liposomes with incorporated major histocompatability complex (MHC) II/peptide complexes. Pharmaceutical Research, 17, 720-726.
Oussoren, C., Storm, G., & Crommelin, D. J. A. (2000). Liposomes for local sustained drug release. In J. Senior, & M. Radomsky (Eds.), Sustained release injectable products (pp. 137-180). interpharm Press.
Storm, G., van de Wetering, P., Zuidam, N. J., Cherng, J.-Y., Talsma, H., Crommelin, D. J. A., & Hennink, W. E. (2000). Methacrylate-based polyplexes as transfection agent. NATO Sci.ser., Ser.A 323. In Targeting of Drugs: Strategies for Gene Constructs and Delivery (pp. 192-199)
Corvo, M. L., Boerman, O. C., Oyen, W. J. G., Jorge, J. C. S., Cruz, M. E., Crommelin, D. J. A., & Storm, G. (2000). Subcutaneous administration of superoxide ismutase entrapped in long circulating liposomes. Pharmaceutical Research, 17, 600-606.
van de Wetering, P., Schuurmans-Nieuwenbroek, N. M. E., van Steenbergen, M. J., Crommelin, D. J. A., & Hennink, W. E. (2000). Copolymers of 2-(dimethylamino)ethyl methacrylate with ethoxytriethylene glycol methacrylate or N-vinyl-pyrrolidone as gene transfer agents. Journal of Controlled Release, 64, 193-203.
van Slooten, M. L., Visser, A. J. W. G., Hoek, A., Storm, G., Crommelin, D. J. A., & Jiskoot, W. (2000). Conformational stability of human interferon-gamma on association with and dissociation from liposomes. Journal of Pharmaceutical Sciences, 89, 1605-1619.
Bos, G. W., Trullas-Jimeno, A., Jiskoot, W., Crommelin, D. J. A., & Hennink, W. E. (2000). Sterilization of poly(dimethylamino)ethyl methacrylate-based transfer complexes. International Journal of Pharmaceutics, 211, 79-88.
Stenekes, R. J. H., Loebis, A. E., Fernandes, C. M., Crommelin, D. J. A., & Hennink, W. E. (2000). Controlled release of liposomes from biodegradable dextran microspheres: a novel delivery concept. Pharmaceutical Research, 17, 690-695.
van Slooten, M. L., Storm, G., Zoephel, A., Kupcu, Z., Boerman, O. C., Crommelin, D. J. A., Wagner, E., & Kircheis, R. (2000). Liposomes containing interferon-gamma as adjuvant in tumor cell vaccines. Pharmaceutical Research, 17, 42-48.
van de Weert, M., Hoechstetter, J., Hennink, W. E., & Crommelin, D. J. A. (2000). The effect of a water/organic interface on the structural stability of lysozyme. Journal of Controlled Release, 68, 351-359.
van de Weert, M., van 't Hof, R., van der Weerd, J., Heeren, R. M., Posthuma, G., Hennink, W. E., & Crommelin, D. J. A. (2000). Lysozyme distribution and conformation in a biodegradable polymer matrix as determined by FTIR techniques. Journal of Controlled Release, 68, 31-40.
van Slooten, M. L., Boerman, O. C., Romoren, K., Kedar, E., Crommelin, D. J. A., & Storm, G. (2000). Liposomes as sustained release system for human interferon-y: biopharmaceutical aspects. Biochimica et Biophysica Acta, 1530, 134-145.
Kettenes-van den Bosch, J. J., Vernooij, E. A. A. M., Underberg, W. J. M., & Crommelin, D. J. A. (2000). Chemical stability of liposomes and liposome components. SÖFW-Journal, 126, 32-36.
Zuidam, N. J., Posthuma, G., de Vries, E. T., Crommelin, D. J. A., Hennink, W. E., & Storm, G. (2000). Effects of physicochemical characteristics of poly(2-(dimethylamino)ethylmethacrylate)-based polyplexes on cellular association and internalization. Journal of Drug Targeting, 8, 51-66.
Overige resultaten
Hennink, W. E., & Crommelin, D. J. A. (2000). Stabilisation and storage of nucleic acids for transformation when not incorporated into viruses. (Patent No. EP 1022340).
1999
Wetenschappelijke publicaties
van, R. AJ., Wauben, MH., Grosfeld-Stulemeyer, MC., van, E. W., & Crommelin, DJ. (1999). Liposomes with incorporated MHC class II/peptide complexes as antigen presenting vesicles for specific T cell activation. Pharmaceutical Research. https://doi.org/10.1023/a:1018864005620
van Dijk-Wolthuis, W. N. E., van de Wetering, P., Hinrichs, W. L. J., Hofmeyer, L. J. F., Liskamp, R. M. J., Crommelin, D. J. A., & Hennink, W. E. (1999). A versatile method for the conjugation of proteins and peptides to poly[2-(dimethylamino)ethyl methacrylate]. Bioconjugate Chemistry, 10(4), 687-692. https://doi.org/10.1021/bc980126+
Crommelin, D. J. A. (1999). Science and the regulatory process. A report on the group discussion sessions. Pharmacy and Pharmacology Communications, 5, 3-5.
Vernooij, E. A. A. M., Gentry, C. A., Herron, J. N., Crommelin, D. J. A., & Kettenes-van den Bosch, J. J. (1999). 1H NMR quantification of poly(ethylene glycol)-phosphatidylethanolamine in phospholipid mixtures. Pharmaceutical Research, 16, 1658-1661.
Cherng, J.-Y., Talsma, H., Crommelin, D. J. A., & Hennink, W. E. (1999). Long term stability of poly((2-dimethylamino)ethyl methacrylate)-based gene delivery systems. Pharmaceutical Research, 16, 1417-1423.
van Winden, E. C. A., & Crommelin, D. J. A. (1999). Short term stability of freeze-dried, lyoprotected liposomes. Journal of Controlled Release, 58, 69-86.
Postma, N. S., Crommelin, D. J. A., Eling, W. M., & Zuidema, J. (1999). Treatment with liposome-bound recombinant human tumor necrosis factor-alpha suppresses parasitemia and protects against Plasmodium Berghei K173-induced experimental cerebral malaria in mice. Journal of Pharmacology and Experimental Therapeutics, 288, 114-120.
van Rensen, J. M. L., Wauben, M. H. M., Grosfeld-Stulemeyer, M. C., van Eden, W., & Crommelin, D. J. A. (1999). liposomes with incorporated MHC class II/peptide complexes as antigen presenting vesicles for specific T cell vaccines. Pharmaceutical Research, 16, 198-204.
Crommelin, D. J. A., & Storm, G. (1999). Stealth therapeutic systems: Rationale and Strategies. In G. Gregoriadis, & B. McCormack (Eds.), Targeting of drugs 6; Strategies for stealth therapeutic systems (pp. 25-34). Plenum Press.
Postma, N. S., Hermsen, C. C., Crommelin, D. J. A., Zuidema, J., & Eling, W. M. (1999). Treatment with recombinant human tumour necrosis factor-alpha reduces parasitaemia and prevents Plasmodium Berghei K173-induced experimental cerebral malaria in mice. Parasitology, 118, 7-15.
Cherng, J.-Y., Talsma, H., Verrijk, R., Crommelin, D. J. A., & Hennink, W. E. (1999). The effect of formulation parameters on the size of poly((2-dimethylamino)ethyl methacrylate)-plasmid complexes. European Journal of Pharmaceutics and Biopharmaceutics, 47, 215-224.
Arigita, C., Zuidam, N. J., Crommelin, D. J. A., & Hennink, W. E. (1999). Association and dissociation characteristics of polymer/DNA complexes used for gene delivery. Pharmaceutical Research, 16, 1534-1541.
Vernooij, E. A. A. M., Gentry, C. A., Herron, J. N., Crommelin, D. J. A., & Kettenes-van den Bosch, J. J. (1999). 1H NMR Quantification of poly(Ethylene Glycol)-Phosphatidylethanolaminde in Phospholipid Mixtures. Pharmaceutical Research, 16, 1658-1661.
Mastrobattista, E., Storm, G., van Bloois, L., Reszka, R., Bloemen, P. G. M., Crommelin, D. J. A., & Henricks, P. A. J. (1999). Cellular uptake of liposomes targeted to intercellular adhesion molecule-1 (ICAM-1) on bronchial epithelial cells. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1419, 353-363.
Postma, N. S., Hermsen, C. C., Crommelin, D. J. A., Zuidema, J., & Eling, W. M. (1999). Treatment with recombinant human tumour necrosis factor reduces parasitaemia and prevents Plasmodium Berghei. Experimental Parasitology, 118, 7-15.
Crommelin, D. J. A., van Rensen, J. M. L., Wauben, M. H. M., & Storm, G. (1999). Liposomes in autoimmune diseases: selected applications in immunotherapy and inflammation detection. Journal of Controlled Release, 62, 245-251.
Postma, N. S., Hermsen, C. C., Crommelin, D. J. A., Eling, W. M., & Zuidema, J. (1999). Thiolated recombinant human tumor necrosis factor-alpha protects against Plasmodium Berghei K173-induced experimental cerebral malaria in mice. Antimicrobial Agents and Chemotherapy, 43, 1027-1033.
Cherng, J.-Y., van de Wetering, P., Talsma, H., Crommelin, D. J. A., & Hennink, W. E. (1999). Stabilization of polymer-based gene delivery systems. Journal of Controlled Release, 183, 25-28.
Kadir, F., Oussoren, C., & Crommelin, D. J. A. (1999). liposomal formulations to reduce irritation of intramusculary and subcutaneous administered drugs. In P. K. Gupta, & G. A. Brazeau (Eds.), Injectable drug development, techniques to reduce pain and irritation (pp. 337-354). interpharm Press.
Crommelin, D. J. A. (1999). Absorptie en Toedieningswegen. In J. M. van Ree, & D. D. Breimer (Eds.), Algemene Farmacologie (pp. 21-41). Elsevier/Bunge.
Zwart - van Rijkom, J. E. F., Leufkens, H. G. M., Crommelin, D. J. A., Rutten, F., & Broekmans, A. W. (1999). Assessment of biotechnology drugs: what are the issues? Health Policy, 47, 255-274.
Corvo, M. L., Boerman, O. C., Oyen, W. J., van Bloois, L., Cruz, M. E., Crommelin, D. J. A., & Storm, G. (1999). Intravenous administration of superoxide dismutase entrapped in long circulating liposomes. II. In vivo fate in a rat model of adjuvant arthritis. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1419, 325-334.
Stenekes, R. J. H., Franssen, O., Bommel, E. M. G., Crommelin, D. J. A., & Hennink, W. E. (1999). The use of aqueous PEG/dextran phase separation for the preparation of dextran microspheres. International Journal of Pharmaceutics, 183, 29-32.
Overige resultaten
Crommelin, D. J. A., & Hennink, W. E. (1999). Storage of DNA.
1998
Wetenschappelijke publicaties
Fonseca Chacharo, M. J., Vingerhoeds, M. H., Haisma, H. J., Crommelin, D. J. A., & Storm, G. (1998). Development of an optimized immuno-enzymosome formulation for application in cancer therapy. In J. E. Diederichs, & R. H. Muller (Eds.), Future Strategies for Drug Delivery with Particulate Systems (pp. 152-157). CRC Press, Medpham. GmbH. Scient. Publ..
Hincal, A., & Crommelin, D. J. A. (1998). Recent Advances in Peptide and Protein Delivery. Editions de Sant.
Koppenhagen, F. J., Köpcö, Z., Wallner, G., Crommelin, D. J. A., Wagner, E., Storm, G., & Kircheis, R. (1998). Sustained cytokine delivery for anticancer vaccination: liposomes as alternative for gene-transfected tumor cells. Clinical Cancer Research, 4, 1881-1886.
van Rensen, A. J. M. L., Taams, L. S., Grosfeld, M. C., Besseling, A., van Eden, W., Crommelin, D. J. A., Wagner, E., & Storm, G. (1998). MHC II/peptide liposomes as artificial antigen presenting cells. In J. E. Diederichs, & R. H. Muller (Eds.), Future Strategies for Drug Delivery with Particulate Systems Systems (pp. 164-166). CRC Press Medpharm. GmbH. Scient. Publ..
van Winden, E. C. A., Zuidam, N. J., & Crommelin, D. J. A. (1998). Strategies for large scale production and optimized stability of pharmaceutical liposomes developed for parenteral use. In D. D. Lasic, & D. Papahadjopoulos (Eds.), Medical Applications of Liposomes (pp. 567-624). Elsevier Science.
van de Wetering, P., Cherng, J.-Y., Talsma, H., Crommelin, D. J. A., & Hennink, W. E. (1998). 2-(dimethylamino)ethyl methacrylate based (co)polymers as gene transfer agents. Journal of Controlled Release, 53, 145-153.
Samuni, A. M., Crommelin, D. J. A., Zuidam, N. J., & Barenholz, Y. (1998). Differential scanning calorimetry: A tool to assess physical and chemical alterations in liposomes. Journal of Thermal Analysis and Calorimetry, 51, 37-48.
van Winden, E. C. A., & Crommelin, D. J. A. (1998). Thermal analysis of freeze-dried liposome-carbohydrate mixtures with modulated temperature differential scanning calorimetry. Journal of Pharmaceutical Sciences, 87, 231-237.
Vernooij, E. A. A. M., Kettenes-van den Bosch, J. J., & Crommelin, D. J. A. (1998). Rapid determination of acyl chain position in egg phosphatidylcholine by high performance liquid chromatography/electrospray mass spectrometry. Rapid Communications in Mass Spectrometry, 12, 83-86.
Oussoren, C., Eling, W. M., Crommelin, D. J. A., Storm, G., & Zuidema, J. (1998). The influence of the route of administration and liposome composition on the potential of liposomes to protect tissue against local toxicity of two antitumor drugs. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1369, 159-172.
Stenekes, R. J. H., Franssen, O., Bommel, E. M. G., Crommelin, D. J. A., & Hennink, W. E. (1998). The preparation of dextran microspheres in an all-aqueous system: Effect of the formulation parameters on particle characteristics. Pharmaceutical Research, 15, 557-561.
Koppenhagen, F. J., Visser, A. J. W. G., Herron, J. N., Storm, G., & Crommelin, D. J. A. (1998). Interaction of recombinant interleukin-2 with liposomal bilayers. Journal of Pharmaceutical Sciences, 87, 707-714.
Heeremans, J. L. M., Prevost, R., Feitsma, H. M., Kluft, C., & Crommelin, D. J. A. (1998). Clot accumulation characteristics of plasminogen-bearing liposomes in a flow system. Thrombosis and Haemostasis, 79, 144-149.
van Slooten, M. L., Koppenhagen, F. J., Bergers, J. J., Kircheis, R., Crommelin, D. J. A., Wagner, E., & Storm, G. (1998). Liposomal delivery of cytokines for anticancer vaccination. In J. E. Diederichs, & R. H. Muller (Eds.), Strategies for Drug Delivery with Particulate Systems (pp. 184-188). CRC Press Medpharm. GmbH. Scient. Publ..
Nagel, J. D., Storm, G., Varossieau, F. J., Crommelin, D. J. A., & McVie, J. G. (1998). Intraperitoneal administration of mitoxantrone liposomes provides advantageous pharmacokinetics in comparison to i.v. or i.p. administration of free drug: a study in a rat model. Regional Cancer Treatment, 9, 175-180.
Storm, G., & Crommelin, D. J. A. (1998). Liposomes: Quo vadis? Pharmaceutical Science & Technology Today, 1, 19-31.
Talsma, H., Cherng, J.-Y., van de Wetering, P., Crommelin, D. J. A., & Hennink, W. E. (1998). Poly(2-(dimethyl)aminoethyl methacrylate) nanoparticles for gene transfection. In J. E. Diederichs, & R. H. Muller (Eds.), Future Strategies for Drug Delivery with Particulate Systems Systems (pp. 177-183). CRC Press Medpharm. GmbH. Scient. Publ..
van de Weert, M., van 't Hof, R., Hennink, W. E., & Crommelin, D. J. A. (1998). Stability of pharmaceutical proteins in particulate carriers. In S. Frokjaer, L. Christrup, & P. Krogsgaard-Larsen (Eds.), Peptide and Protein Drug Delivery (pp. 359-375). Munksgaard.
Overige resultaten
Crommelin, D. J. A., van Slooten, M. L., Storm, G., Wagner, E., & Kirchies, E. (1998). Tumor Vakzine. (Patent No. DE 197 46 173.5).
1997
Wetenschappelijke publicaties
Cherng, J. Y., Van De Wetering, P., Talsma, H., Crommelin, D. J. A., & Hennink, W. E. (1997). Freeze-drying of poly((2-dimethylamino)ethyl methacrylate)based gene delivery systems. Pharmaceutical Research, 14(12), 1838-1841. https://doi.org/10.1023/A:1012164804441
Crommelin, D. J. A., Daemen, T., Scherphof, G. L., Vingerhoeds, M. H., Heeremans, J. L. M., Kluft, C., & Storm, G. (1997). Liposomes: vehicles for the targeted and controlled delivery of peptides and proteins. Journal of Controlled Release, 46, 164-175.
Crommelin, D. J. A., & Sindelar, R. D. (1997). Pharmaceutical biotechnology, an introduction for pharmacists and pharmaceutical scientists. Harwood Academic Publisher.
Cherng, J.-Y., van de Wetering, P., Talsma, H., Crommelin, D. J. A., & Hennink, W. E. (1997). Freeze-drying of poly((2-dimethylami-no)ethylmethacrylate)-based gene delivery systems. Pharmaceutical Research, 14, 1837-1840.
Vernooij, E. A. A. M., Kettenes-van den Bosch, J. J., & Crommelin, D. J. A. (Accepted/In press). Rapid determination of acyl chain position in egg phosphatidylcholine by high preformance liquid chromatography-electrospray mass spectrometry. In 14th IMSC
Storm, G., & Crommelin, D. J. A. (1997). Colloidal systems for tumor targeting. Hybridoma, 16, 119-125.
van den Elsen, J. M. H., Herron, J. N., Hoogerhout, P., Poolman, J. T., Boel, E., Logtenberg, T., Wilting, J., Crommelin, D. J. A., Kroon, J., & Gros, P. (1997). Bactericidal Antibody Recognition of a PorA Epitope of Neisseria meningitidis: Crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide. Proteins: Structure function and bioinformatics, 29(1), 113-125.
van Winden, E. C. A., & Crommelin, D. J. A. (1997). Long term stability of freeze-dried, lyoprotected doxorubicin liposomes. European Journal of Pharmaceutics and Biopharmaceutics, 43, 295-307.
van den Elsen, J. M. H., Pommeren, E., Poolman, J. T., Wilting, J., Herron, J. N., & Crommelin, D. J. A. (1997). On the interaction between a bactericidal antibody and a PorA epitope of Neisseria meningitidis in outer membrane vesicles: a competitive fluorescence polarization immunoassay. Analytical Biochemistry, 247, 382-388.
Samuni, A. M., Barenholz, Y., Crommelin, D. J. A., & Zuidam, N. J. (1997). Gamma-irradiation damage to liposomes differing in composition and their protection bynitroxides. Free Radical Biology and Medicine, 23, 972-979.
van den Elsen, J. M. H., Herron, J. N., Hoogerhout, P., Poolman, J. T., Boel, E., Logtenberg, T., Wilting, J., & Crommelin, D. J. A. (1997). Bacterial antibody recognition of a PorA epitope of Neisseria meningitidis: crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide. Proteins: Structure function and bioinformatics, 29, 113-125.
Oussoren, C., Zuidema, J., Crommelin, D. J. A., & Storm, G. (1997). Lymphatic uptake and biodistribution of liposomes after subcutaneous injection. I. Influence of the anatomical site of injection. Journal of Lipid Research, 7, 85-99.
van Winden, E. C. A., Zhang, W., & Crommelin, D. J. A. (1997). Effect of freezing rate on the stability of liposomes during freeze-drying and rehydration. Pharmaceutical Research, 14, 1151-1160.
Zhang, W., van Winden, E. C. A., Bouwstra, J. A., & Crommelin, D. J. A. (1997). Enhanced permeability of freeze dried liposomal bilayers upon rehydration. Cryobiology, 35, 277-289.
Storm, G., Vingerhoeds, M. H., Crommelin, D. J. A., & Haisma, H. J. (1997). Immunoliposomes bearing enzymes (immuno-enzymosomes) for site-specific activation of anticancer prodrugs. Advanced Drug Delivery Reviews, 24, 225-231.
Fonseca Chacharo, M. J., van Winden, E. C. A., & Crommelin, D. J. A. (1997). Doxorubicin induces aggrega-tion of small negatively charged liposomes. European Journal of Pharmaceutics and Biopharmaceutics, 43, 9-17.
Oussoren, C., Zuidema, J., Crommelin, D. J. A., & Storm, G. (1997). Lymphatic uptake and biodistribution of liposomes after subcutaneous injection. II. Influence of liposomal size, lipid composition and lipid dose. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1328, 261-272.
Vakpublicaties
Crommelin, D. J. A. (1997). Formulation of Biotech Products, including Biopharmaceutical Considerations. In D. J. A. Crommelin, & R. D. Sindelar (Eds.), Pharmaceutical biotechnology, an introduction for pharmacists and pharmaceutical scientists (pp. 77-99). Harwood Academic Publishers.
1996
Wetenschappelijke publicaties
Cherng, J.-Y., Van De Wetering, P., Talsma, H., Crommelin, D. J. A., & Hennink, W. E. (1996). Effect of size and serum proteins on transfection efficiency of poly ((2-dimethylamino)ethyl methacrylate)-plasmid nanoparticles. Pharmaceutical Research, 13(7), 1038-1042. https://doi.org/10.1023/A:1016054623543
Heeremans, J. L. M., Mijnheer, F. W., Gerritsen, H. R., Prevost, R., Kluft, C., & Crommelin, D. J. A. (1996). Long term stability of lipososomes containing both tissue-type plasminogen activator and glu-plasminogen. International Journal of Pharmaceutics, 129, 191-202.
Cherng, J.-Y., van de Wetering, P., Talsma, H., Crommelin, D. J. A., & Hennink, W. E. (1996). Effect of size and serum proteins on transfection efficiency of poly((2-dimethylamino)ethyl methacrylate)-plasmid nanoparticles. Pharmaceutical Research, 13, 1038-1042.
Vingerhoeds, M. H., Haisma, H. J., Belliot, S. O., Smit, R. H. P., Crommelin, D. J. A., & Storm, G. (1996). Immunoliposomes as enzyme-carriers (Immuno-enzymosomes) for antibody-directed enzyme prodrug therapy (ADEPT): optimization of prodrug activating capacity. Pharmaceutical Research, 13, 604-610.
Scherphof, G. L., & Crommelin, D. J. A. (1996). Cells involved in removing liposomes from the blood circulation: Why are they so special? Journal of Liposome Research, 6, 19-32.
Vingerhoeds, M. H., Steerenberg, P. A., Hendriks, J. J. G. W., Dekker, L. C., Van Hoesel, Q. G. C. M., Crommelin, D. J. A., & Storm, G. (1996). Immunoliposome-mediated targeting of doxorubicin to human ovarian carcinoma in vitro and in vivo. British Journal of Cancer, 74, 1023-1029.
Crommelin, D. J. A. (1996). Extended and controlled release products: considera-ti-ons in future developments. In K. K. Midha, & T. Nagai (Eds.), Bioavailability, bioequivalence and pharmacokinetics studies (pp. 247-250). BCASJ.
Oyen, W. J. G., Boerman, O. C., Storm, G., van Bloois, L., Koenders, E. B., Crommelin, D. J. A., van der Meer, J. W. M., & Corstens, F. H. M. (1996). Labeled StealthR liposomes in experimental infection: an alternative for leukocyte scintigraphy? Nuclear Medicine Communications, 17, 742-748.
Heeremans, J. L. M., Los, P., Prevost, R., Crommelin, D. J. A., & Kluft, C. (1996). Fibrin binding of plasminogen coated liposomes in vitro. Thrombosis and Haemostasis, 75, 134-139.
Zuidam, N. J., Talsma, H., & Crommelin, D. J. A. (1996). Sterilization of lipsomes. In Y. Barenholz, & D. D. Lasic (Eds.), Handbook of Nonmedical Applications of Liposoms. From design to Microreactors. Volume II (pp. 71-80). CRC Press.
Oyen, W. J. G., Boerman, O. C., Storm, G., van Bloois, L., Koenders, E. B., Claessens, R. A. M. J., Perenboom, R. M., Crommelin, D. J. A., van der Meer, J. W. G., & Corstens, F. H. M. (1996). Detecting infection and inflammation with technetium-99m-labeled StealthR liposomes. Journal of Nuclear Medicine, 37, 1392-1397.
Vingerhoeds, M. H., Steerenberg, P. A., Hendriks, J. J. G. W., Crommelin, D. J. A., & Storm, G. (1996). Targeted delivery of diphtheria toxin via immunoliposomes: efficient antitumor activity in the presence of inactivating anti-diphtheria toxin antibodies. FEBS Letters, 395, 245-250.
Bergers, J. J., den Otter, W., & Crommelin, D. J. A. (1996). Liposome based cancer vaccines. Journal of Liposome Research, 339-355.
Zuidam, N. J., Versluis, C., Vernooy, E. A. A. M., & Crommelin, D. J. A. (1996). Gamma-irradiation of liposomes composed of saturated phospholipids. Effect of bilayer composition, size, concentration and absorbed dose on chemical degradation and physical destabilisation of liposomes. Biochimica et Biophysica Acta, 1280, 135-148.
Storm, G., Steerenberg, P. A., van Borssum Waalkes, M., & Crommelin, D. J. A. (1996). Effects of intraperitoneal administration of free and liposome-encapsulated doxorubicin on rat peritoneal exudate cell populations. Journal of Drug Targeting, 255-264.
Vakpublicaties
Crommelin, D. J. A. (1996). Focus on Filgrastim. Clinical Pharmacist, 1.
1995
Wetenschappelijke publicaties
Bloemen, P. G. M., Henricks, P. A. J., van Bloois, L., van den Tweel, M. C., Bloem, A. C., Nijkamp, F. P., Crommelin, D. J. A., & Storm, G. (1995). Adhesion molecules: a new target for immunoliposome-mediated drug delivery. FEBS Letters, 357(2), 140-144. https://doi.org/10.1016/0014-5793(94)01350-A