Publicaties
2023
Wetenschappelijke publicaties
Kim, J. J., Steinson, E. R., Lau, M. S., de Rooij, D. G., Page, D. C., & Kingston, R. E. (2023). Cell type-specific role of CBX2 and its disordered region in spermatogenesis. Genes and Development, 37(13-14), 640-660. https://doi.org/10.1101/gad.350393.122
Merges, G. E., Arévalo, L., Kovacevic, A., Lohanadan, K., de Rooij, D. G., Simon, C., Jokwitz, M., Witke, W., & Schorle, H. (2023). Actl7b deficiency leads to mislocalization of LC8 type dynein light chains and disruption of murine spermatogenesis. Development (Cambridge), 150(21). https://doi.org/10.1242/dev.201593
Cecchini, K., Biasini, A., Yu, T., Säflund, M., Mou, H., Arif, A., Eghbali, A., Colpan, C., Gainetdinov, I., de Rooij, D. G., Weng, Z., Zamore, P., & Ozata, D. M. (2023). The transcription factor TCFL5 responds to A MYB to elaborate the male meiotic program in mice. Reproduction, 165(2), 183-196. Article REP-22-0355. https://doi.org/10.1530/rep-22-0355
Yu, T., Biasini, A., Cecchini, K., Saflund, M., Mou, H., Arif, A., Eghbali, A., de Rooij, D., Weng, Z., Zamore, P. D., & Ozata, D. M. (2023). A-MYB/TCFL5 regulatory architecture ensures the production of pachytene piRNAs in placental mammals. RNA, 29(1), 30-43. https://doi.org/10.1261/rna.079472.122
2021
Wetenschappelijke publicaties
Xu, J., Lu, H., Li, H., Yan, C., Wang, X., Zang, M., de Rooij, D. G., Madabhushi, A., & Xu, E. Y. (2021). Computerized spermatogenesis staging (CSS) of mouse testis sections via quantitative histomorphological analysis. Medical Image Analysis, 70, 1-15. Article 101835. https://doi.org/10.1016/j.media.2020.101835
2020
Wetenschappelijke publicaties
Felipe-medina, N., Caburet, S., Sánchez-sáez, F., Condezo, Y. B., De Rooij, D. G., Gómez-h, L., Garcia-valiente, R., Todeschini, A. L., Duque, P., Sánchez-martin, M. A., Shalev, S. A., Llano, E., Veitia, R. A., & Pendás, A. M. (2020). A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1. eLife, 9, Article e56996. https://doi.org/10.7554/eLife.56996
Dokshin, G. A., Davis, G. M., Sawle, A. D., Eldridge, M. D., Nicholls, P. K., Gourley, T. E., Romer, K. A., Molesworth, L. W., Tatnell, H. R., Ozturk, A. R., De Rooij, D. G., Hannon, G. J., Page, D. C., Mello, C. C., & Carmell, M. A. (2020). GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability. Developmental Cell, 52(1), 53-68.e6. https://doi.org/10.1016/j.devcel.2019.11.006
Gustafson, E. A., Seymour, K. A., Sigrist, K., Rooij, D. G. D. E., & Freiman, R. N. (2020). ZFP628 Is a TAF4b-Interacting Transcription Factor Required for Mouse Spermiogenesis. Molecular and Cellular Biology, 40(7), Article e00228-19. https://doi.org/10.1128/MCB.00228-19
Richardson, N., Gillot, I., Gregoire, E. P., Youssef, S. A., de Rooij, D., de Bruin, A., De Cian, M-C., & Chaboissier, M-C. (2020). Sox8 and Sox9 act redundantly for ovarian-to-testicular fate reprogramming in the absence of R-spondin1 in mouse sex reversals. eLife, 9, Article e53972. https://doi.org/10.7554/eLife.53972
2019
Wetenschappelijke publicaties
Sohni, A., Tan, K., Song, H. W., Burow, D., de Rooij, D. G., Laurent, L., Hsieh, T. C., Rabah, R., Hammoud, S. S., Vicini, E., & Wilkinson, M. F. (2019). The Neonatal and Adult Human Testis Defined at the Single-Cell Level. Cell Reports, 26(6), 1501-1517.e4. https://doi.org/10.1016/j.celrep.2019.01.045
Gomez-H, L., Felipe-Medina1, N., Condezo, Y. B., Garcia-Valiente, R., Ramos, I., Suja, J. A., Barbero, J. L., Roig, I., Sanchez-Martin, M., De Rooij, D. G., Llano, E., & PendasI, A. M. (2019). The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility. PLoS Genetics, 15(8), Article e1008316. https://doi.org/10.1371/journal.pgen.1008316
Kruger, A. N., Brogley, M. A., Huizinga, J. L., Kidd, J. M., de Rooij, D. G., Hu, Y. C., & Mueller, J. L. (2019). A Neofunctionalized X-Linked Ampliconic Gene Family Is Essential for Male Fertility and Equal Sex Ratio in Mice. Current Biology, 29(21), 3699-3706.e5. https://doi.org/10.1016/j.cub.2019.08.057
Endo, T., Mikedis, M. M., Nicholls, P. K., Page, D. C., & de Rooij, D. G. (2019). Retinoic acid and germ cell development in the ovary and testis. Biomolecules, 9(12), Article 775. https://doi.org/10.3390/biom9120775
Ehrmann, I., Crichton, J. H., Gazzara, M. R., James, K., Liu, Y., Grellscheid, S. N., Curk, T., de Rooij, D., Steyn, J. S., Cockell, S., Adams, I. R., Barash, Y., & Elliott, D. J. (2019). An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning. eLife, 8, Article e39304. https://doi.org/10.7554/eLife.39304
2018
Wetenschappelijke publicaties
Hamer, G., & de Rooij, D. G. (2018). Mutations causing specific arrests in the development of mouse primordial germ cells and gonocytes. Biology of Reproduction, 99(1), 75-86. https://doi.org/10.1093/biolre/ioy075
Gregoire, E. P., Stevant, I., Chassot, A-A., Martin, L., Lachambre, S., Mondin, M., de Rooij, D. G., Nef, S., & Chaboissier, M-C. (2018). NRG1 signalling regulates the establishment of Sertoli cell stock in the mouse testis. Molecular and Cellular Endocrinology, 478, 17-31. https://doi.org/10.1016/j.mce.2018.07.004
Hirota, T., Blakeley, P., Sangrithi, M. N., Mahadevaiah, S. K., Encheva, V., Snijders, A. P., ElInati, E., Ojarikre, O. A., de Rooij, D. G., Niakan, K. K., & Turner, J. M. A. (2018). SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice. Developmental Cell, 47(47 (5)), 645-659. Article PMID: 30393076. https://doi.org/10.1016/j.devcel.2018.10.004
2017
Wetenschappelijke publicaties
de Rooij, D. G. (2017). Organization of the Seminiferous Epithelium and the Cycle, and Morphometric Description of Spermatogonial Subtypes (Rodents and Primates). In J. Oatley, & M. Griswold (Eds.), The Biology of Mammalian Spermatogonia (pp. 3-20). Springer Science+Business Media. https://doi.org/10.1007/978-1-4939-7505-1_1
ElInati, E., Russell, H. R., Ojarikre, O. A., Sangrithi, M., Hirota, T., De Rooij, D. G., McKinnon, P. J., & Turner, J. M. A. (2017). DNA damage response protein TOPBP1 regulates X chromosome silencing in the mammalian germ line. Proceedings of the National Academy of Sciences of the United States of America, 114(47), 12536-12541. https://doi.org/10.1073/pnas.1712530114
De Rooij, D. G. (2017). Recent developments in the spermatogonial stem cell field. Animal Reproduction, 14(1), 82-88. https://doi.org/10.21451/1984-3143-AR890
De Rooij, D. G. (2017). The nature and dynamics of spermatogonial stem cells. Development (Cambridge), 144(17), 3022-3030. https://doi.org/10.1242/dev.146571
Bailey, A. S., Batista, P. J., Gold, R. S., Grace Chen, Y., de Rooij, D. G., Chang, H. Y., & Fuller, M. T. (2017). The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline. eLife, 6, Article e26116. https://doi.org/10.7554/eLife.26116
2016
Wetenschappelijke publicaties
Vernet, N., Mahadevaiah, S. K., Decarpentrie, F., Longepied, G., de Rooij, D. G., Burgoyne, P. S., & Mitchell, M. J. (2016). Mouse Y-Encoded Transcription Factor Zfy2 Is Essential for Sperm Head Remodelling and Sperm Tail Development. PLoS One, 11(1), e0145398. https://doi.org/10.1371/journal.pone.0145398
Shum, E. Y., Jones, S. H., Shao, A., Dumdie, J., Krause, M. D., Chan, W-K., Lou, C-H., Espinoza, J. L., Song, H-W., Phan, M. H., Ramaiah, M., Huang, L., McCarrey, J. R., Peterson, K. J., De Rooij, D. G., Cook-Andersen, H., & Wilkinson, M. F. (2016). The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay. Cell, 165(2), 382-95. https://doi.org/10.1016/j.cell.2016.02.046
Faieta, M., Di Cecca, S., de Rooij, D. G., Luchetti, A., Murdocca, M., Di Giacomo, M., Di Siena, S., Pellegrini, M., Rossi, P., & Barchi, M. (2016). A surge of late-occurring meiotic double-strand breaks rescues synapsis abnormalities in spermatocytes of mice with hypomorphic expression of SPO11. Chromosoma, 125(2), 189-203. https://doi.org/10.1007/s00412-015-0544-7
Song, H-W., Bettegowda, A., Lake, B. B., Zhao, A. H., Skarbrevik, D., Babajanian, E., Sukhwani, M., Shum, E. Y., Phan, M. H., Plank, T-D. M., Richardson, M. E., Ramaiah, M., Sridhar, V., de Rooij, D. G., Orwig, K. E., Zhang, K., & Wilkinson, M. F. (2016). The Homeobox Transcription Factor RHOX10 Drives Mouse Spermatogonial Stem Cell Establishment. Cell Reports, 17(1), 149-164. https://doi.org/10.1016/j.celrep.2016.08.090
Gómez-H, L., Felipe-Medina, N., Sánchez-Martín, M., Davies, O. R., Ramos, I., García-Tuñón, I., de Rooij, D. G., Dereli, I., Tóth, A., Barbero, J. L., Benavente, R., Llano, E., & Pendas, A. M. (2016). C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility. Nature Communications, 7, 13298. https://doi.org/10.1038/ncomms13298
Xu, Z., Song, Z., Li, G., Tu, H., Liu, W., Liu, Y., Wang, P., Wang, Y., Cui, X., Liu, C., Shang, Y., de Rooij, D. G., Gao, F., & Li, W. (2016). H2B ubiquitination regulates meiotic recombination by promoting chromatin relaxation. Nucleic Acids Research, 44(20), 9681-9697. https://doi.org/10.1093/nar/gkw652
Rico-Leo, E. M., Moreno-Marín, N., González-Rico, F. J., Barrasa, E., Ortega-Ferrusola, C., Martín-Muñoz, P., Sánchez-Guardado, L. O., Llano, E., Alvarez-Barrientos, A., Infante-Campos, A., Catalina-Fernández, I., Hidalgo-Sánchez, M., de Rooij, D. G., Pendás, A. M., Peña, F. J., Merino, J. M., & Fernández-Salguero, P. M. (2016). piRNA-associated proteins and retrotransposons are differentially expressed in murine testis and ovary of aryl hydrocarbon receptor deficient mice. Biology Open, 6(12). https://doi.org/10.1098/rsob.160186
Vernet, N., Mahadevaiah, S. K., de Rooij, D. G., Burgoyne, P. S., & Ellis, P. J. I. (2016). Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes. Human Molecular Genetics, 25(24), 5300-5310. https://doi.org/10.1093/hmg/ddw344
2015
Wetenschappelijke publicaties
Ahmed, E. A., Scherthan, H., & de Rooij, D. G. (2015). DNA Double Strand Break Response and Limited Repair Capacity in Mouse Elongated Spermatids. International Journal of Molecular Sciences, 16(12), 29923-35. https://doi.org/10.3390/ijms161226214
2011
Wetenschappelijke publicaties
Chi, M. N., Auriol, J., Jégou, B., Kontoyiannis, D. L., Turner, J. M., de Rooij, D. G., & Morello, D. (2011). The RNA-binding protein ELAVL 1/HuR is essential for mouse spermatogenesis, acting both at meiotic and postmeiotic stages. Molecular Biology of the Cell, 22, 2875-2885.
Chassot, A. A., Gregoire, E. P., Lavery, R., Taketo, M. M., de Rooij, D. G., Adams, I. R., & Chaboissier, M. C. (2011). RSPO1/beta-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary. PLoS One, e25641. https://doi.org/10.1371/journal.pone.0025641
2010
Wetenschappelijke publicaties
Ahmed, E. A., Philippens, M. E. P., Kal, H. B., de Rooij, D. G., & de Boer, P. (2010). Genetic probing of homologous recombination and non-homologous end joining during meiotic prophase in irradiated mouse spermatocytes. Mutation Research-Genetic Toxicology and Environmental Mutagenesis, 688(1-2), 12-18. http://www.ncbi.nlm.nih.gov/pubmed/20167225
Ahmed Abdel Gaber, E. A. A., de Boer, P., Philippens, M. E. P., Kal, H. B., & de Rooij, D. G. (2010). Parpl-XRCC1 and the repair of DNA double strand breaks in mouse round spermatids. Mutation Research-Genetic Toxicology and Environmental Mutagenesis, 683(1), 84-90. http://www.ncbi.nlm.nih.gov/pubmed/19887075
Carlomagno, G., van Bragt, M. P. A., Korver, C. M., Repping, S., de Rooij, D. G., & van Pelt, A. M. M. (2010). BMP4-induced differentiation of a rat spermatogonial stem cell line causes changes in its cell adhesionproperties. Biology of Reproduction, 83(5), 742-749.
2009
Wetenschappelijke publicaties
Sadri-Ardekani, H., van Daalen, S. K. M., Korver, C. M., Roepers-Gajadien, H. L., Koruji, M., Hovingh, S. E., de Reijke, T. M., de la Rosette, J. J. M. C. H., van der Veen, F., Mizrak, S. C., de Rooij, D. G., Repping, S., & van Pelt, A. M. M. (2009). Long term proliferation of human spermatogonial stem cells in vitro. JAMA - The Journal of The American Medical Association, 302, 2127-2134.
Klothur-Seetharam, U., Teerds, K. J., de Rooij, D. G., Wendling, O., McBurney, M., Sassone-Corsi, P., & Davidson, I. (2009). The histone deacetylase SIRT1 controls male fertility through regulation of hypothalamic-pituitary gonadotrophin signalling. Biology of Reproduction, 80, 384-391.
de Rooij, D. G. (2009). The spermatogonial stem cell niche. Microscopy Research and Technique, 72, 580-585.
Ahmed Abdel Gaber, E. A. A., & de Rooij, D. G. (2009). Staging of mouse deminiferous tubule cross-sections. Methods in Molecular Biology, 558, 263-277.
Liska, F., Gosele, C., Rivkin, E., Tres, L., Cardoso, M. C., Domaing, P., Krejci, E., Snajdr, P., Lee-Kirsch, M. A., de Rooij, D. G., Kren, V., Krenová, D., Kierszenbaum, L. A., & Hubner, N. (2009). Rat hd mutation reveals essential rol of Lip8 in mammalian spermiogenesis. Biology of Reproduction, 81, 1196-1205.
Ahmed Abdel Gaber, E. A. A., Barten - van Rijbroek, A. D., Kal, H. B., Sadri-Ardekani, H., Mizrak, S. C., van Pelt, A. M. M., & de Rooij, D. G. (2009). Proliferative activity in vitro and DNA repair indicate that adult mouse and human Sertoli cells are not terminally differentiated quiescent cells. Biology of Reproduction, 80, 1084-1091. http://www.ncbi.nlm.nih.gov/pubmed/19164176
de Rooij, D. G. (2009). Spermatogonial stem cells. In H. Baharvand (Ed.), Trends in Stem Cell Biology and Technology (pp. 149-162). Humana Press.
Overige resultaten
Krawetz, S. A., de Rooij, D. G., & Hedger, M. P. (2009). Andrology in Hesse: Molecular aspects of male fertility. 1087-1982. Abstract from The 5th International Workshop on Molecular Andrology.
2008
Wetenschappelijke publicaties
Aponte, P. M., & de Rooij, D. G. (2008). Biomanipulation of bovine spermatogonial stem cells. Animal Reproduction, 5, 16-22.
Ahmed, E. A., & de Rooij, D. G. (2008). Staging of mouse seminiferous tubule cross-sections. In S. Keeney (Ed.), Methods in Molecular BIology Humana Press.
van Bragt, M. P. A., Roepers-Gajadien, H. L., Korver, C. M., Bogerd, J., Okuda, A., Eggen, B. J. L., de Rooij, D. G., & van Pelt, A. M. M. (2008). Expression of pluripotency marker, UTF1, is restricted to a subpopulation of early A spermatogonia in rat testis. Reproduction, 136, 33-40.
Aponte, P. M., Soda, T., Teerds, K. J., Mizrak, S. C., van de Kant, H. J. G., & de Rooij, D. G. (2008). Propagation of bovine spermatogonial stem cells in vitro. Reproduction, 136, 543-557.
de Rooij, D. G., & Mizrak, S. C. (2008). Deriving multipotent stem cells from mouse spermatogonial stem cells: a new tool for developmental and clinical research. Development (Cambridge, England), 135, 2207-2213.
Rijntjes, E., Wientjes, A. T., Swarts, H. J. M., de Rooij, D. G., & Teerds, K. J. (2008). Dietary induced hyperthyroidism marginally affects neonatal testicular development. Journal of Andrology, 29(6), 643-653.
Mahadevaiah, S., Bourc'his, D., de Rooij, D. G., Bestor, T. H., Turner, J. M. A., & Burgoyne, P. S. (2008). Extensive meiotic asynapsis in mice antagonises meiotic silencing of unsynapsed chromatin and consequently disrupts meiotic sex chromosome inactivation. Journal of Cell Biology, 182, 263-276.
de Rooij, D. G., Repping, S., & van Pelt, A. M. M. (2008). Role for adhesion molecules in the spermatogonial cell niche. Preview. Cell Stem Cell, 3(5), 467-468.
Anderson, E. L., Baltus, A. E., Roepers-Gajadien, H. L., Hassold, T. J., de Rooij, D. G., van Pelt, A. M. M., & Page, D. C. (2008). Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice. Proceedings of the National Academy of Sciences of the United States of America, 105(39), 14976-14980.
Chassot, A. A., Ranc, F., Gregoire, E. P., Roepers-Gajadien, H. L., Taketo, M. M., Camerino, G., de Rooij, D. G., Schedl, A., & Chaboissier, M. C. (2008). Activation of ß-catenin signalling by Rspo1 controls differentiation of the mammalian ovary. Human Molecular Genetics, 17, 1264-1277.
Barchi, M. I., Roig, M., di Giacomo, M., de Rooij, D. G., Keeney, S., & Jasin, M. (2008). ATM promotes the obligate XY crossover and both crossover control and chromosome axis integrity on autosomes. PLoS Genetics, 4(e1000076).
2007
Wetenschappelijke publicaties
Carmell, M. A., Girard, A., van de Kant, H. J. G., Bourc'his, D., Bestor, T. H., de Rooij, D. G., & Hannon, G. J. (2007). MIWI2 Is Essential for Spermatogenesis and Repression of Transposons in the Mouse Male Germline. Developmental Cell, 12, 503-514.
Jaroszyynski, L., Dev, A., Li, M., Meinhardt, A., de Rooij, D. G., Mueller, C., Boehm, D., de Wolf, S., Adham, I. M., Wulf, G., Engel, W., & Nayernia, K. (2007). Asthenoteratozoospermia in mice lacking testis expressed gene 18 (Tex18). Molecular Human Reproduction, 13(3), 155-163.
Ahmed Abdel Gaber, E. A. A., van der Vaart, A., Barten, A., Kal, H. B., Chen, J., Lou, Z., Minter-Dykhouse, K., Bartkova, J., Boer, P., & de Rooij, D. G. (2007). Differences in DNA double strand breaks repair in male germ cell types: Lessons learned from a differential expression of Mdc1 and 53BP1. DNA Repair, 6, 1243-1254.
Bolcun-Filas, E., Costa, Y., Speed, R., Taggart, M., Benavente, R., de Rooij, D. G., & Cooke, H. J. (2007). SYCE2 is required for DSB repair, sc assembly and homologous recombination. Journal of Cell Biology, 176(6), 741-747.
Mizrak, S. C., Renault-Mihara, F., Párraga, M., Bogerd, J., van de Kant, H. J. G., López-Casas, P. P., Paz, M., del Mazo, J., & de Rooij, D. G. (2007). Phosphoprotein enriched in astrocytes-15 is expressed in mouse testis and protects spermatocytes from apoptosis. Reproduction, 133, 743-751.
Ono, N., van der Heijden, I., Scheffer, G. L., van de Wetering, K., van Deemter, E., de Haas, M., Boerke, A., Gadella, B. M., de Rooij, D. G., Neefjes, J. J., Groothuis, T. A. M., Oomen, L., Brocks, L., Ishakawa, T., & Borst, P. (2007). Multidrug resistance-associated protein 9 (ABCC12) is present in mouse and boar sperm. Biochemical Journal, 406(1), 31-40.
Bannister, L. A., Pezza, R. J., Donaldson, J. R., de Rooij, D. G., Schimenti, K. J., Camerini-Otero, R. D., & Schimenti, J. C. (2007). A dominant, recombination-defective allele of Dmc1 causing male-specific sterility. PloS Biology [E], 5(5), 1016-1025.
2006
Wetenschappelijke publicaties
de Rooij, D. G. (2006). Regulation of spermatogonial stem cell behavior in vivo and in vitro. Animal Reproduction, 3(2), 130-134.
Mizrak, S. C., Bogerd, J., Lopez-Casas, P. P., Parraga, M., Del Mazo, J., & de Rooij, D. G. (2006). Expression of stress inducible protein 1 (Stip1) in the mouse testis. Molecular Reproduction and Development, 73(11), 1361-1366.
Aponte Garcia, P. M., Soda, T., van de Kant, H. J. G., & de Rooij, D. G. (2006). Basic features of bovine spermatogonial culture and effects of glial cell line-derived neurotropic factor. Theriogenology, 65, 1828-1847.
de Rooij, D. G. (2006). Rapid expansion of the spermatogonial stem cell tool box. Proceedings of the National Academy of Sciences of the United States of America, 103(21), 7939-7940.
Baltus, A. E., Menkel, D. B., Hu, Y. C., Goodheart, M. L., Carpenter, A. E., de Rooij, D. G., & Page, D. C. (2006). In germ cells of mouse embryonic ovaries, the decision to enter meiosis precedes premeiotic DNA replication. Nature Genetics, 38, 1430-1434.
2005
Wetenschappelijke publicaties
de Rooij, D. G. (2005). Stem cells of the seminiferous epithelium. In E. V. Greer (Ed.), Trends in stem cell research (pp. 169-190). Nova Science.
Vakpublicaties
Goriely, A., McVean, G. A., van Pelt, A. M. M., O'Rourke, A. W., Wall, S. A., de Rooij, D. G., & Wilkie, A. O. (2005). Gain of function animo acid substitutions drive positive selection of FGFR2 mutations in human spermatogonia. In Proceedings of the national Academy of Science USA. (pp. 6051-6056)
Overige resultaten
van Pelt, A. M. M., & de Rooij, D. G. (2005). Estrogens affect protein expression in fetal gonocytes. Reproduction Nutrition Development, 45, 209-210.
Bourguiba, S., van Pelt, A. M. M., & de Rooij, D. G. (2005). Detection of mitochondrially encoded Cytochrome C oxidase subunit I in adult rat germ cells. Reproduction Nutrition Development, 45, 228-229.
Barchi, M., Mahadevaiah, S., Giacomo di, M., Baudat, F., de Rooij, D. G., Burgoyne, P. S., Jasin, M., & Keeney, S. (2005). Surveillance of recombination defects in mouse spermatocytes yields distinct responses despite elimination at an identical development stage. Molecular and Cellular Biology, 25, 7203-7215.
Goriely, A., McVean, G. A. T., van Pelt, A. M. M., O'Rourke, A. W., Wall, S. A., de Rooij, D. G., & Wilkie, A. O. M. (2005). Protein-driven positive selection of FGFR2 mutations in human spermatogonia. Proceedings of the National Academy of Sciences of the United States of America, 102, 6051-6065.
van Bragt, M. P. A., Ciliberti, N., Stanford, W. L., de Rooij, D. G., & van Pelt, A. M. M. (2005). LY6A/E (SCA-1) expression in the mouse testis. Biology of Reproduction, 73, 634-638.
Aponte Garcia, P. M., de Rooij, D. G., & Bastidas, P. (2005). Testicular development in Brahman bulls. Theriogenology, 64, 1440-1445.
2004
Wetenschappelijke publicaties
Pancharatnam, J., Ikeda, Y., Jamin, S. P., Zhao, L., de Rooij, D. G., Themmen, A. P. N., Behringer, R. R., & Parker, K. L. (2004). Cell-specific knockout of steroidogenic factor 1 reveals its essential roles in gonadal function. Molecular Endocrinology, 18(7), 1610-1619.
de Rooij, D. G., & van Bragt, M. P. A. (2004). Leydig cells: testicular side population harbors transplantable Leydig stem cells. Endocrinology, 145(9), 4009-4010.
Ashley, T., Gaeth, A. P., Creemers, L. B., Hack, A. M., & de Rooij, D. G. (2004). Correlation of meiotic events in testis sections and microspreads of mouse spermatocytes relative to the mid-pachytene checkpoint. Chromosoma, 113, 126-136.
de Rooij, D. G. (2004). Spermatogonial stem cells. In K. Turksen (Ed.), Adult stem cells (pp. 19-35). Humana Press.
Hamer, G., Kal, H. B., Westphal, C. H., Ashley, T., & de Rooij, D. G. (2004). Ataxia telangiectasia mutated expression and activation in the testis. Biology of Reproduction, 70(4), 1206-1212.
Modaressi, M. H., Cheng, M., Tarnasky, H. A., Lamarche-Vane, N., & de Rooij, D. G. (2004). A novel testicular RhoGAP-domain protein induces apoptosis. Biology of Reproduction, 71, 1980-1990.
Buaas, F. W., Kirsh, A. L., Sharma, M., McLean, D. J., Morris, J. L., Griswold, M. D., de Rooij, D. G., & Braun, R. E. (2004). Plzf is required in adult male germ cells for stem cell self-renewal. Nature Genetics, 36(6), 647-652.
Ashley, T., Westphal, C., Plug-de Maggio, A., & de Rooij, D. G. (2004). The mammalian mid-pachytene checkpoint: meiotic arrest in spermatocytes with a mutation in Atm alone or in combination with a Trp53 (p53) or Cdkn 1a (p21/cip1) mutation. Cytogenetic and Genome Research, 107, 256-262.
Boer, P., Giele, M., Lock, M. T. W. T., de Rooij, D. G., Giltay, J. C., Hochstenbach, P. F. R., & te Velde, E. R. (2004). Kinetics of meiosis in azoospermic males: a joint histological and cytological approach. Cytogenetic and Genome Research, 105(1), 36-46.
https://dspace.library.uu.nl/bitstream/handle/1874/11543/Lock_04_Kinetics-of-meiosis-in-azoospermic.pdf?sequence=2
https://dspace.library.uu.nl/bitstream/handle/1874/11543/Lock_04_Kinetics-of-meiosis-in-azoospermic.pdf?sequence=2
Chaboissier, M. C., Kobayashi, A., Vidal, V. I. P., Lützkendorf, S., van de Kant, H. J. G., Wegner, M., de Rooij, D. G., Behringer, R. R., & Schedl, A. (2004). Functional analysis of Sox8 and Sox9 during sex determination in the mouse. Development (Cambridge, England), 131, 1891-1901.
Overige resultaten
de Rooij, D. G. (2004). Testicular stem cells.. Abstract from XXth Congress of the European Society of Human Reproduction and Embryology., Berlin.
2003
Wetenschappelijke publicaties
Hamer, G., Roepers-Gajadien, H. L., van Duyn-Goedhart, A., Gademan, I. S., Kal, H. B., van Buul, P. P. W., Ashley, T., & de Rooij, D. G. (2003). Function of DNA-protein kinase catalytic subunit during the early meiotic prophase without Ku70 and Ku86. Biology of Reproduction, 68, 717-721.
de Rooij, D. G., & van Pelt, A. M. M. (2003). Spermatogonial stem cell biology. ARBS Annual Review of Biomedical Sciences, 5, 105-114.
Hamer, G., Roepers-Gajadien, H. L., van Duyn-Goedhart, A., Gademan, I. S., Kal, H. B., van Buul, P. P. W., & de Rooij, D. G. (2003). DNA double-strand breaks and gamma-H2AX signaling in the testis. Biology of Reproduction, 68, 628-634.
Hamer, G., Roepers-Gajadien, H. L., Gademan, I. S., Kal, H. B., & de Rooij, D. G. (2003). Intercellular bridges and apoptosis in clones of male germ cells. International Journal of Andrology, 26, 348-353.
Izadyar, F., den Ouden, K., Creemers, L. B., Posthuma, G., Parvinen, M., & de Rooij, D. G. (2003). Proliferation and differentiation of bovine type A spermatogonia during long-term culture. Biology of Reproduction, 68, 272-281.
Izadyar, F., den Ouden, K., Stout, T. A. E., Stout, J., Coret, J. P., Lankveld, D. P. K., Spoormakers, T. J. P., Colenbrander, B. A., Oldenbroek, J. K., v.d. Ploeg, K. D., Woelders, H., Kal, H. B., & de Rooij, D. G. (2003). Autologous and homologous transplantation of bovine spermatogonial stem cells. Reproduction, 126, 765-774.
Overige resultaten
de Rooij, D. G. (2003). Communicatie- en regulatiemechanismen in het lichaam. X.
de Rooij, D. G., & Boer, P. (2003). Specific arrests of spermatogenesis in genetically modified and mutant mice. Cytogenetic and Genome Research, 103, 267-276.
van Pelt, A. M. M., de Rooij, D. G., & van Dissel-Emiliani, F. M. F. (2003). In vitro differentiation of an established embryonal gonocyte cell line. 226. Abstract from Testis Workshop.
2002
Wetenschappelijke publicaties
Izadyar, F., Spierenberg, G. T., Creemers, L. B., den Ouden, K., & de Rooij, D. G. (2002). Isolation and purification of type A spermatogonia from the bovine testis. Reproduction, 124, 85-94.
van Pelt, A. M. M., Roepers-Gajadien, H. L., Gademan, I. S., Creemers, L. B., de Rooij, D. G., & van Dissel-Emiliani, F. M. F. (2002). Establishment of cell lines with rat spermatogonial stem cell characteristics. Endocrinology, 143, 1845-1850.
Izadyar, F., Matthijs-Rijsenbilt, J. J., den Ouden, K., Creemers, L. B., Woelders, H., & de Rooij, D. G. (2002). Development of a cryopreservation protocol for type A spermatogonia. Journal of Andrology, 23, 537-545.
Creemers, L. B., Meng, X., den Ouden, K., van Pelt, A. M., Izadyar, F., Santoro, M., Sariola, H., & de Rooij, D. G. (2002). Transplantation of germ cells from glial cell line-derived neurotrophic factor-overexpressing mice to host testes depleted of endogenous spermatogenesis by fractionated irradiation. Biology of Reproduction, 66(6), 1579-1584.
de Rooij, D. G., Creemers, L. B., den Ouden, K., & Izadyar, F. (2002). Spermatogonial stem cell development. In F. F. G. Rommerts, & K. J. Teerds (Eds.), Testicular tangrams (pp. 121-138)
Creemers, L. B., den Ouden, K., van Pelt, A. M. M., & de Rooij, D. G. (2002). Maintenance of adult mouse type A spermatogonia in vitro: influence of serum and growth factors and comparison with prepubertal spermatogonial cell culture. Reproduction, 124, 791-799.
Overige resultaten
van Pelt, A. M. M., Cetin, S. C., de Rooij, D. G., & van Dissel-Emiliani, F. M. F. (2002). Establishment of gonocyte cell lines.. Abstract from XIIth European Workshop on Molecular an Cellular Endocrinology of the Testis. Doorwerth, Netherlands April 2002.
Izadyar, F., den Ouden, K., Stout, T. A. E., Coret, J. P., Lankveld, D. P. K., Rijkenhuizen, A. B. M., & de Rooij, D. G. (2002). Succesful allogeneic transplantation of bovine spermatogonial stem cells.. Abstract from Society Study Reproduction 35th Annual Meeting. Baltimore, USA, July 2002. PP. 291.
Izadyar, F., den Ouden, K., Creemers, L. B., Posthuma, G., Parvinen, M., & de Rooij, D. G. (2002). In vitro development of type A spermatogonia to spermatids.. Abstract from XIIth European Workshop on Molecular and Cellular Endocrinology of the Testis. Doorwerth, Netherlands April 2002..
Hamer, G., Roepers-Gajadien, H. L., van Duijn-Goedhart, A., Gademan, I. S., Kal, H. B., van Buul, P. P. W., Ashley, T., & de Rooij, D. G. (2002). Apoptosis in the scid testis.. Abstract from XIIth European Workshop on Molecular and Cellular Endocrinology of the Testis. Doorwerth, Netherland April 2002..
2001
Wetenschappelijke publicaties
Peters, M. A. J., de Rooij, D. G., Teerds, K. J., & van Sluijs, F. J. (2001). Spermatogenesis and testicular tumors in the ageing dog. Journal of Reproduction and Fertility, 120, 443-452.
Peters, M. A. J., de Rooij, D. G., Teerds, K. J., & van Sluijs, F. J. (2001). Spermatogenesis and testicular tumors in ageing dogs. Journal of reproduction and fertility. Supplement, 57, 419-421.
Peters, M. A. J., Teerds, K. J., de Rooij, D. G., & van Sluijs, F. J. (2001). Use of antibodies against LH receptor, 3ß-hydroxysteroid dehydrogenase and vimentin to characterize different types of testicular tumour in dogs. Journal of Reproduction and Fertility, 121, 287-296.
2000
Wetenschappelijke publicaties
Beumer, T. L., Roepers-Gajadien, H. L., Gademan, I. S., Kal, H. B., & de Rooij, D. G. (2000). Involvement of the D-type cyclins in germ cell proliferation and differentiation in the mouse. Biology of Reproduction, 63, 1893-1898.
Beumer, T. L., Roepers-Gajadien, H. L., Gademan, I. S., Lock, M. T. W. T., Kal, H. B., & de Rooij, D. G. (2000). Apoptosis regulation in the testis: involvement of Bcl-2 family members. Molecular Reproduction and Development, 56, 353-359.
Kuroda, M., Sok, J., Webb, L., Baechtold, H., Urano, F., Yin, Y., Chung, P., de Rooij, D. G., Akhmedov, A., Ashley, T., & Ron, D. (2000). Male sterility and enhanced radiation sensitivity in TLS-/-mice. EMBO Journal, 19, 453-462.
Peters, M. A. J., de Jong, F. H., Teerds, K. J., de Rooij, D. G., Dieleman, S. J., & van Sluijs, F. J. (2000). Ageing, testicular tumours and the pituitary-testis axis in dogs. Journal of Endocrinology, 166, 153-161.
Shuttlesworth, G. A., de Rooij, D. G., Huhtaniemi, I., Reissmann, T., Russell, L. D., Shetty, G., Wilson, G., & Meistrich, M. L. (2000). Enhancement of a spermatogonial proliferation and differentiation in irradiated rats by gonadotropin releasing hormone antagonist administration. Endocrinology, 141, 37-49.
Izadyar, F., Creemers, L. B., van Dissel-Emiliani, F. M. F., van Pelt, A. M. M., & de Rooij, D. G. (2000). Spermatogonial stem cell transplantation. Molecular and Cellular Endocrinology, 169, 21-26.
Baart, E. B., de Rooij, D. G., Keegan, K. S., & de Boer, P. (2000). Distribution of Atr protein in primary spermatocytes of a mouse chromosomal mutant: a comparison of preparation techniques. Chromosoma, 109, 139-147.
de Rooij, D. G., & Russell, L. D. (2000). All you wanted to know about spermatogonia but were afraid to ask. Journal of Andrology, 21, 776-798.
Meng, X., Lindahl, M., Hyvonen, M. E., Parvinen, M., de Rooij, D. G., Hess, M. W., Raatikainen-Ahokas, A., Sainio, K., Rauvala, H., Lakso, M., Pichel, J. G., Westphal, H., Saarma, M., & Sariola, H. (2000). Regulation of cell fate decision of undifferentiated spermatogonia by GDNF. Science, 287, 1489-1493.
de Rooij, D. G., Schrans-Stassen, B. H. G. J., van Pelt, A. M. M., Shuttlesworth, G. A., Meistrich, M. L., Okabe, M., & Nishimune, Y. (2000). Regulation of the differentiation of the undifferentiated spermatogonia. In E. Goldberg (Ed.), The Testis: From Stem Cell to Sperm Function (pp. 43-54). Springer.
1999
Wetenschappelijke publicaties
de Vries, S., Baart, E. B., Dekker, M., Siezen, A., de Rooij, D. G., de Boer, P., & te Riele, H. (1999). Mouse mutS-like protein Msh5 is required for proper chromosome synapsis in male and female meiosis. Genes and Development, 13, 523-531.
van Pelt, A. M. M., de Rooij, D. G., van der Burg, B., van der Saag, P. T., Gustafsson, J. A., & Kuiper, G. G. J. M. (1999). Ontogeny of estrogen receptor beta expression in rat testis. Endocrinology, 140, 478-483.
Schrans-Stassen, B. H. G. J., van de Kant, H. J. G., de Rooij, D. G., & van Pelt, A. M. M. (1999). Differential expression of c-kit in mouse undifferentiated and differentiating type A spermatogonia. Endocrinology, 140, 5894-5900.
de Rooij, D. G., Okabe, M., & Nishimune, Y. (1999). Arrest of spermatogonial differentiation in jsd/jsd, Sl17H/Sl17H and cryptorchid mice. Biology of Reproduction, 61, 842-847.
Beumer, T. L., Kiyokawa, H., Roepers-Gajadien, H. L., van den Bos, A. C., Lock, M. T. W. T., Gademan, I. S., Rutgers, D. H., Koff, A., & de Rooij, D. G. (1999). Regulatory role of p27-kip1 in the mouse and human testis. Endocrinology, 140, 1834-1840.
Overige resultaten
de Boer, P., Giele, M., Lock, M. T. W. T., de Rooij, D. G., van de Hoeven, FA., Giltay, J. C., Hochstenbach, P. F. R., van Kooy, R., te Velde, E. R., & Pearson, P. L. (1999). A comprehensive protocol for investigating the kinetics of meiosis in azoospermic males. Poster session presented at R de Graaf symposium 9-11 Sept. 1999, Zeist.
1998
Wetenschappelijke publicaties
Gaemers, I. C., van Pelt, A. M. M., Themmen, A. P. N., & de Rooij, D. G. (1998). Isolation and characterization of all-trans-retinoic acid-responsive genes in the rat testis. Molecular Reproduction and Development, 50, 1-6.
Gaemers, I. C., van Pelt, A. M. M., van der Saag, P. T., Hoogerbrugge, J. W., Themmen, A. P. N., & de Rooij, D. G. (1998). Differential expression pattern of retinoid X receptors in adult murine testicular cells implies varying roles for these receptors in spermatogenesis. Biology of Reproduction, 58, 1351-1356.
Beumer, T. L., Roepers-Gajadien, H. L., van Buul, P. P. W., Gill-Gomez, G., Gademan, I. S., Rutgers, D. H., & de Rooij, D. G. (1998). The role of the tumor suppressor P53 in spermatogenesis. Cell Death and Differentiation, 5, 669-677.
de Rooij, D. G., & Grootegoed, J. A. (1998). Spermatogonial stem cells. Current Opinion in Cell Biology, 10, 694-701.
de Rooij, D. G., van Beek, M. E. A. B., Rutgers, D. H., van Duijn-Goedhart, A., & van Buul, P. P. W. (1998). Radioprotective effect of misoprostol on mouse spermatogonial stem cells. Genetical Research, 72, 185-189.
Gaemers, I. C., Sonneveld, E., van Pelt, A. M. M., Schrans-Stassen, B. H. G. J., Themmen, A. P. N., van der Saag, P. T., & de Rooij, D. G. (1998). The effect of 9-cis-retinoic acid on proliferation and diffeerntiation of growth-arrested A spermatogonia and nuclear retinoid receptor gene expression in the vitamin-A deficient mouse testis. Endocrinology, 139, 4269-4276.
Slegtenhorst, K. E., de Rooij, D. G., Verhoef-Post, M., Ruiz, A., Uilenbroek, J. T. J., van de Kant, H. J. G., Bakker, C. E., Oostra, B. A., Grootegoed, J. A., & Themmen, A. P. N. (1998). Macro-orchidism in Fmr1 knock out mice is caused by increased Sertoli cell proliferation during testis development. Endocrinology, 139, 156-162.
Beumer, T. L., Roepers-Gajadien, H. L., van Buul, P. P. W., Gill-Gomez, G., Gademan, I. S., Rutgers, D. H., & de Rooij, D. G. (1998). The onset of the development of the adult-type Leydig cell population in the rat is affected by the height of neonatal thyroid hormone levels. Biology of Reproduction, 59, 344-350.
1997
Wetenschappelijke publicaties
de Rooij, D. G., & van Dissel-Emiliani, F. M. F. (1997). Regulation and proliferation of stem cells in the male germ line. In C. S. Potter (Ed.), Current Book Contents (pp. 283-313). Acad. Press Ltd..
Bleijs-van Pelt, A. M. M., Morena, A. R., van Dissel-Emiliani, F. M. F., van Boitani, C., Gaemers, I. C., de Rooij, D. G., & Stefani, M. (1997). Isolation of the synchronized A spermatogonia from adult vitamin A-deficient rat testis. Biology of Reproduction, 55, 439-444.
de Miguel, M. P., de Boer-Brouwer, M., de Rooij, D. G., Paniagua, R., & van Dissel-Emiliani, F. M. F. (1997). Ontogeny and localization of an oncostatin M-like protein in the rat testis: Its possible role at the start of spermatogenesis. Cell Growth & Differentiation, 8, 611-618.
Gaemers, I. C., Bleijs-van Pelt, A. M. M., van der Saag, P. T., Hoogerbrugge, J. W., Themmen, A. P. N., & de Rooij, D. G. (1997). Effect of retinoid status of the messenger ribonucleic acid expression of nuclear retinoid receptors O, ?, and y, and retinoid X receptors O, ?, and y in the mouse testis. Endocrinology, 138, 1544-1551.
van Buul, P. P. W., van Duijn-Goedhart, A., de Rooij, D. G., & Sankaranarayanan, K. (1997). Differential radioprotective effects of misoprostol in DNA repair-proficient and -deficient or radiosensitive cell systems. International Journal of Radiation Biology, 71, 259-264.
Beumer, T. L., Roepers-Gajadien, H. L., Gademan, I. S., Rutgers, D. H., & de Rooij, D. G. (1997). P21 (Cip1/WAF1) expression in the mouse testis before and after X-irradiation. Molecular Reproduction and Development, 47, 240-247.
1996
Wetenschappelijke publicaties
Morin, P. J., van Wichen, D. F., Kinzler, K. W., van den Hurk, R., de Rooij, D. G., & van Dissel-Emiliani, F. M. F. (1996). Leukemia inhibitory factor (LIF) and ciliary neurotrophic factor (CNTF) promote the survival of Sertoli cells and gonocytes in a co-culture system. Endocrinology, 137, 1885-1893.