Sleutelpublicaties
Du, W., Guo, H., Nijman, V. S., Doedt, J., van der Vries, E., van der Lee, J., Li, Z., Boons, G.-J., van Kuppeveld, F. J. M., de Vries, E., Matrosovich, M., & de Haan, C. A. M. (2019). The 2nd sialic acid-binding site of influenza A virus neuraminidase is an important determinant of the hemagglutinin-neuraminidase-receptor balance. PLoS Pathogens, 15(6), Article e1007860. https://doi.org/10.1371/journal.ppat.1007860
Du, W., Wolfert, M. A., Peeters, B., van Kuppeveld, F. J. M., Boons, G.-J., de Vries, E., & de Haan, C. A. M. (2020). Mutation of the second sialic acid-binding site of influenza A virus neuraminidase drives compensatory mutations in hemagglutinin. PLoS Pathogens, 16(8), 1-20. Article e1008816. https://doi.org/10.1371/journal.ppat.1008816
de Vries, R. P., Tscherne, D. M., Wienholts, M., Cobos-Jiménez, V., Scholte, F., García-Sastre, A., Rottier, P. J. M., & de Haan, C. A. M. (2011). Dissection of the Influenza A Virus Endocytic Routes Reveals Macropinocytosis as an Alternative Entry Pathway. PLoS Pathogens, 7(3), 1-19. Article e1001329. https://doi.org/10.1371/journal.ppat.1001329
de Vries, E., de Vries, R. P., Wienholts, M. J., Floris, C. E., Jacobs, M. S., Heuvel, A. V. D., Rottier, P. J. M., & de Haan, C. A. M. (2012). Influenza A virus entry into cells lacking sialylated N-glycans. Proceedings of the National Academy of Sciences of the United States of America, 109(19), 7457-7462. https://doi.org/10.1073/pnas.1200987109
Guo, H., Rabouw, H., Slomp, A., Dai, M., van der Vegt, F., van Lent, J. W. M., McBride, R., Paulson, J. C., de Groot, R. J., van Kuppeveld, F. J. M., de Vries, E., & de Haan, C. A. M. (2018). Kinetic analysis of the influenza A virus HA/NA balance reveals contribution of NA to virus-receptor binding and NA-dependent rolling on receptor-containing surfaces. PLoS Pathogens, 14(8), Article e1007233. https://doi.org/10.1371/journal.ppat.1007233
Cornelissen, L. A. H. M., de Vries, R. P., de Boer-Luijtze, E. A., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2010). A single immunization with soluble recombinant trimeric hemagglutinin protects chickens against highly pathogenic avian influenza virus H5N1. PLoS One, 5(5), Article e10645. https://doi.org/10.1371/journal.pone.0010645
https://dspace.library.uu.nl/bitstream/handle/1874/202907/Cornelissen%2C%2520L.A.%2520et%2520al.%2520PLoS%2520One%2520%282010%295%285%29%2520e10645.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/202907/Cornelissen%2C%2520L.A.%2520et%2520al.%2520PLoS%2520One%2520%282010%295%285%29%2520e10645.pdf?sequence=1
Burkard, C., Verheije, M. H., Wicht, O., van Kasteren, S. I., van Kuppeveld, F. J., Haagmans, B. L., Pelkmans, L., Rottier, P. J. M., Bosch, B. J., & de Haan, C. A. M. (2014). Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway in a Proteolysis-Dependent Manner. PLoS Pathogens, 10(11), Article e1004502. https://doi.org/10.1371/journal.ppat.1004502
Hagemeijer, M. C., Verheije, M. H., Ulasli, M., Shaltiël, I. A., de Vries, L. A., Reggiori, F., Rottier, P. J. M., & de Haan, C. A. M. (2010). Dynamics of coronavirus replication-transcription complexes. Journal of Virology, 84(4), 2134-2149. https://doi.org/10.1128/JVI.01716-09
Publicaties
2024
Wetenschappelijke publicaties
Hoornweg, T. E., Schaftenaar, W., Rutten, V. PMG., & Haan, C. D. (2024). Low gH/gL (Sub)Species-Specific Antibody Levels Indicate Elephants at Risk of Fatal Elephant Endotheliotropic Herpesvirus Hemorrhagic Disease. Viruses, 16(2), Article 268. https://doi.org/10.3390/v16020268
https://dspace.library.uu.nl/bitstream/handle/1874/435923/viruses-16-00268.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/435923/viruses-16-00268.pdf?sequence=1
Pascha, M. N., Ballegeer, M., Roelofs, M. C., Meuris, L., Albulescu, I. C., Kuppeveld, F. J. M. V., Hurdiss, D. L., Bosch, B.-J., Zeev-Ben-Mordehai, T., Saelens, X., & Haan, C. A. M. D. (2024). Nanoparticle display of neuraminidase elicits enhanced antibody responses and protection against influenza A virus challenge in mice. Research Square. https://doi.org/10.21203/rs.3.rs-3579434/v1
https://dspace.library.uu.nl/bitstream/handle/1874/436082/748a8378-0382-43eb-8ee8-d7467ff4d5a6.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/436082/748a8378-0382-43eb-8ee8-d7467ff4d5a6.pdf?sequence=1
Lapierre, L., Roland, J. T., Manning, E. H., Caldwell, C., Glenn, H. L., Vidalain, P.-O., Tangy, F., Hogue, B. G., Haan, C. D., & Goldenring, J. R. (2024). Coronavirus M Protein Trafficking in Epithelial Cells Utilizes a Myosin Vb Splice Variant and Rab10. Cells, 13(2), 1-18. Article 126. https://doi.org/10.3390/cells13020126
https://dspace.library.uu.nl/bitstream/handle/1874/435539/cells-13-00126.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/435539/cells-13-00126.pdf?sequence=1
2023
Wetenschappelijke publicaties
Liu, M., Morewood, R., Yoshisada, R., Pascha, M. N., Hopstaken, A. J. P., Tarcoveanu, E., Poole, D. A., de Haan, C. A. M., Nitsche, C., & Jongkees, S. A. K. (2023). Selective thiazoline peptide cyclisation compatible with mRNA display and efficient synthesis. Chemical Science, 14(38), 10561-10569. https://doi.org/10.1039/d3sc03117a
Wallace, L. E., Vries, E. D., Kuppeveld, F. J. M. V., & Haan, C. A. M. D. (2023). Neuraminidase-dependent entry of influenza A virus is determined by hemagglutinin receptor-binding specificity. Journal of Virology, 97(10), Article e0060223. https://doi.org/10.1128/jvi.00602-23
https://dspace.library.uu.nl/bitstream/handle/1874/433046/wallace-et-al-2023-neuraminidase-dependent-entry-of-influenza-a-virus-is-determined-by-hemagglutinin-receptor-binding.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/433046/wallace-et-al-2023-neuraminidase-dependent-entry-of-influenza-a-virus-is-determined-by-hemagglutinin-receptor-binding.pdf?sequence=1
Lakerveld, A. J., Gelderloos, A. T., Schepp, R. M., de Haan, C. A. M., van Binnendijk, R. S., Rots, N. Y., van Beek, J., van Els, C. A. C. M., & van Kasteren, P. B. (2023). Difference in respiratory syncytial virus-specific Fc-mediated antibody effector functions between children and adults. Clinical and Experimental Immunology, 214(1), 79-93. Article uxad101. https://doi.org/10.1093/cei/uxad101
https://dspace.library.uu.nl/bitstream/handle/1874/434278/uxad101.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/434278/uxad101.pdf?sequence=1
Liu, M., Bakker, A. S., Narimatsu, Y., van Kuppeveld, F. J. M., Clausen, H., de Haan, C. A. M., & de Vries, E. (2023). H3N2 influenza A virus gradually adapts to human-type receptor binding and entry specificity after the start of the 1968 pandemic. Proceedings of the National Academy of Sciences of the United States of America, 120(31), Article e2304992120. https://doi.org/10.1073/pnas.2304992120
Liu, M., van Kuppeveld, F. J., de Haan, C. A., & de Vries, E. (2023). Gradual adaptation of animal influenza A viruses to human-type sialic acid receptors. Current Opinion in Virology, 60, 1-15. Article 101314. https://doi.org/10.1016/j.coviro.2023.101314
Wu, X., Goebbels, M., Chao, L., Wennekes, T., van Kuppeveld, F. J. M., de Vries, E., & de Haan, C. A. M. (2023). Kinetic analysis of paramyxovirus-sialoglycan receptor interactions reveals virion motility. PLoS Pathogens, 19(3), Article e1011273. https://doi.org/10.1371/journal.ppat.1011273
de Vries, E., & de Haan, C. A. (2023). Letter to the editor: Highly pathogenic influenza A(H5N1) viruses in farmed mink outbreak contain a disrupted second sialic acid binding site in neuraminidase, similar to human influenza A viruses. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 28(7), Article 2300085. https://doi.org/10.2807/1560-7917.ES.2023.28.7.2300085
Liu, M., Yoshisada, R., Amedi, A., Hopstaken, A. J. P., Pascha, M. N., de Haan, C. A. M., Geerke, D. P., Poole, D. A., & Jongkees, S. A. K. (2023). An efficient, site-selective and spontaneous peptide macrocyclisation during in vitro translation. Chemistry-A European Journal, 29(14), 1-11. Article e202203923. https://doi.org/10.1002/chem.202203923
https://dspace.library.uu.nl/bitstream/handle/1874/431027/Chemistry_A_European_J_-_2022_-_Liu.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/431027/Chemistry_A_European_J_-_2022_-_Liu.pdf?sequence=1
2022
Wetenschappelijke publicaties
Porbahaie, M., Savelkoul, H. F. J., de Haan, C. A. M., Teodorowicz, M., & van Neerven, R. J. J. (2022). Direct Binding of Bovine IgG-Containing Immune Complexes to Human Monocytes and Their Putative Role in Innate Immune Training. Nutrients, 14(21), Article 4452. https://doi.org/10.3390/nu14214452
Liu, M., Huang, L. Z. X., Smits, A. A., Büll, C., Narimatsu, Y., van Kuppeveld, F. J. M., Clausen, H., de Haan, C. A. M., & de Vries, E. (2022). Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions. Nature Communications, 13(1), 1-12. Article 4054. https://doi.org/10.1038/s41467-022-31840-0
van de Ven, K., van Dijken, H., Du, W., de Heij, F., Mouthaan, J., Spijkers, S., van den Brink, S., Roholl, P., de Haan, C. A. M., & de Jonge, J. (2022). Varying Viral Replication and Disease Profiles of H2N2 Influenza in Ferrets Is Associated with Virus Isolate and Inoculation Route. Journal of Virology, 96(14), 1-14. Article e0073222. https://doi.org/10.1128/jvi.00732-22
de Vries, E., Guo, H., Du, W., Liu, M., van Kuppeveld, F. J. M., & de Haan, C. A. M. (2022). Quantification of Receptor Association, Dissociation, and NA-Dependent Motility of Influenza A Particles by Biolayer Interferometry. In Glycovirology: Methods and Protocols (pp. 123-140). (Methods in Molecular Biology; Vol. 2556). Humana Press. https://doi.org/10.1007/978-1-0716-2635-1_10
Pascha, M. N., Thijssen, V., Egido, J. E., Linthorst, M. W., van Lanen, J. H., van Dongen, D. A. A., Hopstaken, A. J. P., van Kuppeveld, F. J. M., Snijder, J., de Haan, C. A. M., & Jongkees, S. A. K. (2022). Inhibition of H1 and H5 Influenza A Virus Entry by Diverse Macrocyclic Peptides Targeting the Hemagglutinin Stem Region: ACS Chemical Biology. ACS Chemical Biology, 17(9), 2425-2436. https://doi.org/10.1021/acschembio.2c00040
Spencer Clinton, J. L., Hoornweg, T., Tan, J., Peng, R., Schaftenaar, W., Rutten, VP., de Haan, X., & Ling, P. D. (2022). EEHV1A glycoprotein B subunit vaccine elicits humoral and cell-mediated immune responses in mice. Vaccine, 40(35), 5131-5140. https://doi.org/10.1016/j.vaccine.2022.07.016
Hoornweg, T. E., Perera, V. P., Karunarathne, R. N. S., Schaftenaar, W., Mahakapuge, T. A. N., Kalupahana, A. W., Rutten, V. P. M. G., & de Haan, C. A. M. (2022). Young elephants in a large herd maintain high levels of elephant endotheliotropic herpesvirus-specific antibodies and do not succumb to fatal haemorrhagic disease. Transboundary and emerging diseases, 69(5), e3379-e3385. https://doi.org/10.1111/tbed.14644
Wei, X., Du, W., Duca, M., Yu, G., de Vries, E., de Haan, C. A. M., & Pieters, R. J. (2022). Preventing Influenza A Virus Infection by Mixed Inhibition of Neuraminidase and Hemagglutinin by Divalent Inhibitors. Journal of Medicinal Chemistry, 65(10), 7312-7323. https://doi.org/10.1021/acs.jmedchem.2c00319
2021
Wetenschappelijke publicaties
Creytens, S., Pascha, M. N., Ballegeer, M., Saelens, X., & de Haan, C. A. M. (2021). Influenza Neuraminidase Characteristics and Potential as a Vaccine Target. Frontiers in Immunology, 12, 1-19. Article 786617. https://doi.org/10.3389/fimmu.2021.786617
Zaree, P., Torano, J. S., de Haan, C. A. M., Scheltma, R. A., Barendregt, A., Thijssen, V., Yu, G., Flesch, F., & Pieters, R. J. (2021). The assessment of Pseudomonas aeruginosa lectin LecA binding characteristics of divalent galactosides using multiple techniques. Glycobiology, 31(11), 1490-1499. https://doi.org/10.1093/glycob/cwab074
Nason, R., Büll, C., Konstantinidi, A., Sun, L., Ye, Z., Halim, A., Du, W., Sørensen, D. M., Durbesson, F., Furukawa, S., Mandel, U., Joshi, H. J., Dworkin, L. A., Hansen, L., David, L., Iverson, T. M., Bensing, B. A., Sullam, P. M., Varki, A., ... Narimatsu, Y. (2021). Display of the human mucinome with defined O-glycans by gene engineered cells. Nature Communications, 12(1), 1-16. Article 4070. https://doi.org/10.1038/s41467-021-24366-4
Klooster, J. P. T., Bol-Schoenmakers, M., van Summeren, K., van Vliet, A. L. W., de Haan, C. A. M., van Kuppeveld, F. J. M., Verkoeijen, S., & Pieters, R. (2021). Enterocytes, fibroblasts and myeloid cells synergize in anti-bacterial and anti-viral pathways with IL22 as the central cytokine. Communications Biology, 4(1), 1-13. Article 631. https://doi.org/10.1038/s42003-021-02176-0
Dai, M., Du, W., Martínez-Romero, C., Leenders, T., Wennekes, T., Rimmelzwaan, G. F., van Kuppeveld, F. J. M., Fouchier, R. A. M., Garcia-Sastre, A., de Vries, E., & de Haan, C. A. M. (2021). Analysis of the Evolution of Pandemic Influenza A(H1N1) Virus Neuraminidase Reveals Entanglement of Different Phenotypic Characteristics. mBio, 12(3), 1-18. Article e00287-21. https://doi.org/10.1128/mBio.00287-21
Wallace, L. E., Liu, M., van Kuppeveld, F., de Vries, E., & de Haan, C. A. M. (2021). Respiratory mucus as a virus-host range determinant. Trends in Microbiology, 29(11), 983-992. https://doi.org/10.1016/j.tim.2021.03.014
https://dspace.library.uu.nl/bitstream/handle/1874/418777/PIIS0966842X21000731.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/418777/PIIS0966842X21000731.pdf?sequence=1
Hoornweg, T. E., Schaftenaar, W., Maurer, G., van den Doel, P. B., Molenaar, F. M., Chamouard-Galante, A., Vercammen, F., Rutten, V. P. M. G., & de Haan, C. A. M. (2021). Elephant Endotheliotropic Herpesvirus Is Omnipresent in Elephants in European Zoos and an Asian Elephant Range Country. Viruses, 13(2), Article 283. https://doi.org/10.3390/v13020283
Du, W., de Vries, E., van Kuppeveld, F. J. M., Matrosovich, M., & de Haan, C. A. M. (2021). Second sialic acid-binding site of influenza A virus neuraminidase: Binding receptors for efficient release. The FEBS journal, 288(19), 5598-5612. https://doi.org/10.1111/febs.15668
2020
Wetenschappelijke publicaties
Ghosh, S., Dellibovi-Ragheb, T. A., Kerviel, A., Pak, E., Qiu, Q., Fisher, M., Takvorian, P. M., Bleck, C., Hsu, V. W., Fehr, A. R., Perlman, S., Achar, S. R., Straus, M. R., Whittaker, G. R., de Haan, C. A. M., Kehrl, J., Altan-Bonnet, G., & Altan-Bonnet, N. (2020). β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway. Cell, 183(6), 1520-1535.e14. https://doi.org/10.1016/j.cell.2020.10.039
Verdijk, P., van der Plas, J. L., van Brummelen, E. M. J., Jeeninga, R. E., de Haan, C. A. M., Roestenberg, M., Burggraaf, J., & Kamerling, I. M. C. (2020). First-in-human administration of a live-attenuated RSV vaccine lacking the G-protein assessing safety, tolerability, shedding and immunogenicity: a randomized controlled trial. Vaccine, 38(39), 6088-6095. https://doi.org/10.1016/j.vaccine.2020.07.029
Nederend, M., van Stigt, A. H., Jansen, J. H. M., Jacobino, S. R., Brugman, S., de Haan, C. A. M., Bont, L. J., van Neerven, R. J. J., & Leusen, J. H. W. (2020). Bovine IgG Prevents Experimental Infection With RSV and Facilitates Human T Cell Responses to RSV. Frontiers in Immunology, 11, Article 1701. https://doi.org/10.3389/fimmu.2020.01701
Zhao, S., Schuurman, N., Tieke, M., Quist, B., Zwinkels, S., van Kuppeveld, F., de Haan, C. A. M., & Egberink, H. (2020). Serological screening of influenza A virus antibodies in cats and dogs indicates frequent infection with different subtypes. Journal of Clinical Microbiology, 58(11), Article e01689-20. https://doi.org/10.1128/JCM.01689-20
Du, W., Wolfert, M. A., Peeters, B., van Kuppeveld, F. J. M., Boons, G.-J., de Vries, E., & de Haan, C. A. M. (2020). Mutation of the second sialic acid-binding site of influenza A virus neuraminidase drives compensatory mutations in hemagglutinin. PLoS Pathogens, 16(8), 1-20. Article e1008816. https://doi.org/10.1371/journal.ppat.1008816
Peng, L., Du, W., Balhuizen, M. D., Haagsman, H. P., de Haan, C. A. M., & Veldhuizen, E. J. A. (2020). Antiviral Activity of Chicken Cathelicidin B1 Against Influenza A Virus. Frontiers in Microbiology, 11, Article 426. https://doi.org/10.3389/fmicb.2020.00426
van Erp, E. A., Lakerveld, A. J., de Graaf, E., Larsen, M. D., Schepp, R. M., Hipgrave Ederveen, A. L., Ahout, I. M., de Haan, C. A., Wuhrer, M., Luytjes, W., Ferwerda, G., Vidarsson, G., & van Kasteren, P. B. (2020). Natural killer cell activation by respiratory syncytial virus-specific antibodies is decreased in infants with severe respiratory infections and correlates with Fc-glycosylation. Clinical & translational immunology, 9(2), Article e1112. https://doi.org/10.1002/cti2.1112
Cong, Y., Ulasli, M., Schepers, H., Mauthe, M., V'kovski, P., Kriegenburg, F., Thiel, V., de Haan, C. A. M., & Reggiori, F. (2020). Nucleocapsid protein recruitment to replication-transcription complexes plays a crucial role in coronaviral life cycle. Journal of Virology, 94(4), Article e01925-19. https://doi.org/10.1128/JVI.01925-19
de Vries, E., Du, W., Guo, H., & de Haan, C. A. M. (2020). Influenza A Virus Hemagglutinin-Neuraminidase-Receptor Balance: Preserving Virus Motility. Trends in Microbiology, 28(1), 57-67. https://doi.org/10.1016/j.tim.2019.08.010
https://dspace.library.uu.nl/bitstream/handle/1874/392089/Influenza_A_virus.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/392089/Influenza_A_virus.pdf?sequence=1
2019
Wetenschappelijke publicaties
Schepp, R. M., de Haan, C. A. M., Wilkins, D., Layman, H., Graham, B. S., Esser, M. T., & Berbers, G. A. M. (2019). Development and Standardization of a High-Throughput Multiplex Immunoassay for the Simultaneous Quantification of Specific Antibodies to Five Respiratory Syncytial Virus Proteins. mSphere, 4(2), Article e00236-19. https://doi.org/10.1128/mSphere.00236-19
Du, W., Guo, H., Nijman, V. S., Doedt, J., van der Vries, E., van der Lee, J., Li, Z., Boons, G.-J., van Kuppeveld, F. J. M., de Vries, E., Matrosovich, M., & de Haan, C. A. M. (2019). The 2nd sialic acid-binding site of influenza A virus neuraminidase is an important determinant of the hemagglutinin-neuraminidase-receptor balance. PLoS Pathogens, 15(6), Article e1007860. https://doi.org/10.1371/journal.ppat.1007860
Lu, W., Du, W., Somovilla, V. J., Yu, G., Haksar, D., de Vries, E., Boons, G.-J., de Vries, R. P., de Haan, C. A. M., & Pieters, R. J. (2019). Enhanced Inhibition of Influenza A Virus Adhesion by Di- and Trivalent Hemagglutinin Inhibitors. Journal of Medicinal Chemistry, 62(13), 6398-6404. https://doi.org/10.1021/acs.jmedchem.9b00303
Mazur, N. I., Horsley, N., Englund, J. A., Nederend, M., Magaret, A., Kumar, A., Jacobino, S. R., de Haan, C. A. M., Khatry, S. K., LeClerq, S. C., Steinhoff, M. C., Tielsch, J. M., Katz, J., Graham, B. S., Bont, L. J., Leusen, J. H. W., & Chu, H. Y. (2019). Breast milk prefusion F Immunoglobulin G as a correlate of protection against respiratory syncytial virus acute respiratory illness. Journal of Infectious Diseases, 219(1), 59-67. https://doi.org/10.1093/infdis/jiy477
2018
Wetenschappelijke publicaties
Dong, W., Bhide, Y., Sicca, F., Meijerhof, T., Guilfoyle, K., Engelhardt, O. G., Boon, L., de Haan, C. A. M., Carnell, G., Temperton, N., de Vries-Idema, J., Kelvin, D., & Huckriede, A. (2018). Cross-Protective Immune Responses Induced by Sequential Influenza Virus Infection and by Sequential Vaccination With Inactivated Influenza Vaccines. Frontiers in Immunology, 9, Article 2312. https://doi.org/10.3389/fimmu.2018.02312
Tomar, J., Biel, C., de Haan, C. A. M., Rottier, P. J. M., Petrovsky, N., Frijlink, H. W., Huckriede, A., Hinrichs, W. L. J., & Peeters, B. (2018). Passive inhalation of dry powder influenza vaccine formulations completely protects chickens against H5N1 lethal viral challenge. European Journal of Pharmaceutics and Biopharmaceutics, 133, 85-95. https://doi.org/10.1016/j.ejpb.2018.10.008
Du, W., Dai, M., Li, Z., Boons, G.-J., Peeters, B., van Kuppeveld, F. J. M., de Vries, E., & de Haan, C. A. M. (2018). Substrate binding by the 2 sialic acid-binding site of influenza A virus N1 neuraminidase contributes to enzymatic activity. Journal of Virology, 92(20), Article e01243-18. https://doi.org/10.1128/JVI.01243-18
Guo, H., Rabouw, H., Slomp, A., Dai, M., van der Vegt, F., van Lent, J. W. M., McBride, R., Paulson, J. C., de Groot, R. J., van Kuppeveld, F. J. M., de Vries, E., & de Haan, C. A. M. (2018). Kinetic analysis of the influenza A virus HA/NA balance reveals contribution of NA to virus-receptor binding and NA-dependent rolling on receptor-containing surfaces. PLoS Pathogens, 14(8), Article e1007233. https://doi.org/10.1371/journal.ppat.1007233
Baggen, J., Hurdiss, D. L., Zocher, G., Mistry, N., Roberts, R. W., Slager, J. J., Guo, H., van Vliet, A. L. W., Wahedi, M., Benschop, K., Duizer, E., de Haan, C. A. M., de Vries, E., Casasnovas, J. M., de Groot, R. J., Arnberg, N., Stehle, T., Ranson, N. A., Thibaut, H. J., & van Kuppeveld, F. J. M. (2018). Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus. Proceedings of the National Academy of Sciences of the United States of America, 115(2), 397-402. https://doi.org/10.1073/pnas.1713284115
Job, E. R., Schotsaert, M., Ibañez, L. I., de Smet, A., Ysenbaert, T., Roose, K., Dai, M., de Haan, C. A. M., Kleanthous, H., Vogel, T. U., & Saelens, X. (2018). Antibodies directed towards neuraminidase N1 control disease in a mouse model of influenza. Journal of Virology, 92(4), Article e01584-17. https://doi.org/10.1128/JVI.01584-17
2017
Wetenschappelijke publicaties
Li, W., Hulswit, R. J. G., Widjaja, I., Raj, V. S., McBride, R., Peng, W., Widagdo, W., Tortorici, M. A., van Dieren, B., Lang, Y., van Lent, J. W. M., Paulson, J. C., de Haan, C. A. M., de Groot, R. J., van Kuppeveld, F. J. M., Haagmans, B. L., & Bosch, B.-J. (2017). Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein. Proceedings of the National Academy of Sciences of the United States of America, 114(40), E8508-E8517. https://doi.org/10.1073/pnas.1712592114
Cong, Y., Kriegenburg, F., de Haan, C. A. M., & Reggiori, F. (2017). Coronavirus nucleocapsid proteins assemble constitutively in high molecular oligomers. Scientific Reports, 7(1), Article 5740. https://doi.org/10.1038/s41598-017-06062-w
van Erp, E. A., van Kasteren, P. B., Guichelaar, T., Ahout, I. M. L., de Haan, C. A. M., Luytjes, W., Ferwerda, G., & Wicht, O. (2017). In vitro enhancement of RSV infection by maternal antibodies does not explain disease severity in infants. Journal of Virology, 91(21), Article e00851-17 . https://doi.org/10.1128/JVI.00851-17
de Vries, R. P., Peng, W., Grant, O. C., Thompson, A. J., Zhu, X., Bouwman, K. M., de la Pena, A. T. T., van Breemen, M. J., Ambepitiya Wickramasinghe, I. N., de Haan, C. A. M., Yu, W., McBride, R., Sanders, R. W., Woods, R. J., Verheije, M. H., Wilson, I. A., & Paulson, J. C. (2017). Three mutations switch H7N9 influenza to human-type receptor specificity. PLoS Pathogens, 13(6), Article e1006390. https://doi.org/10.1371/journal.ppat.1006390
Dai, M., McBride, R., Dortmans, J. C. F. M., Peng, W., Bakkers, M. J. G., de Groot, R. J., van Kuppeveld, F. J. M., Paulson, J. C., de Vries, E., & de Haan, C. A. M. (2017). Mutation of the 2(nd) Sialic Acid-Binding Site Resulting in Reduced Neuraminidase Activity Preceded Emergence of H7N9 Influenza A Virus. Journal of Virology, 91(9), Article e00049-17. https://doi.org/10.1128/JVI.00049-17
Jans, J., Wicht, O., Widjaja, I., Ahout, I. M. L., de Groot, R., Guichelaar, T., Luytjes, W., de Jonge, M. I., de Haan, C. A. M., & Ferwerda, G. (2017). Characteristics of RSV-Specific Maternal Antibodies in Plasma of Hospitalized, Acute RSV Patients under Three Months of Age. PLoS One, 12(1), Article e0170877. https://doi.org/10.1371/journal.pone.0170877
Peeters, B., Reemers, S., Dortmans, J., de Vries, E., de Jong, M., van de Zande, S., Rottier, P. J. M., & de Haan, C. A. M. (2017). Genetic versus antigenic differences among highly pathogenic H5N1 avian influenza A viruses: Consequences for vaccine strain selection. Virology, 503, 83-93. https://doi.org/10.1016/j.virol.2017.01.012
Parsons, L. M., An, Y., de Vries, R. P., de Haan, C. A. M., & Cipollo, J. F. (2017). Glycosylation Characterization of an Influenza H5N7 Hemagglutinin Series with Engineered Glycosylation Patterns: Implications for Structure-Function Relationships. Journal of Proteome Research, 16(2), 398–412. https://doi.org/10.1021/acs.jproteome.6b00175
Guo, H., de Vries, E., McBride, R., Dekkers, J., Bouwman, K. M., Nycholat, C., Verheije, M. H., Paulson, J. C., van Kuppeveld, F. J. M., & de Haan, C. A. M. (2017). Highly Pathogenic Influenza A(H5Nx) Viruses with Altered H5 Receptor-Binding Specificity. Emerging Infectious Diseases, 23(2). https://doi.org/10.3201/eid2302.161072
2016
Wetenschappelijke publicaties
Hulswit, R. J. G., de Haan, C. A. M., & Bosch, B.-J. (2016). Coronavirus Spike Protein and Tropism Changes. Advances in Virus Research, 96, 29-57. https://doi.org/10.1016/bs.aivir.2016.08.004
Mauthe, M., Langereis, M., Jung, J., Zhou, X., Jones, A., Omta, W., Tooze, S. A., Stork, B., Paludan, S. R., Ahola, T., Egan, D., Behrends, C., Mokry, M., de Haan, X., van Kuppeveld, F., & Reggiori, F. (2016). An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication. Journal of Cell Biology, 214(5), 619-635. https://doi.org/10.1083/jcb.201602046
Dai, M., Guo, H., Dortmans, J., Dekkers, J., Nordholm, J., Daniels, R., van Kuppeveld, F. J. M., de Vries, E., & de Haan, C. A. M. (2016). Identification of residues that affect oligomerization and/or enzymatic activity of influenza virus H5N1 neuraminidase proteins. Journal of Virology, 90(20), 9457-9470. https://doi.org/10.1128/JVI.01346-16
van Mechelen, L., Luytjes, W., de Haan, C. A. M., & Wicht, O. (2016). RSV neutralization by palivizumab, but not by monoclonal antibodies targeting other epitopes, is augmented by Fc gamma receptors. Antiviral Research, 132, 1-5. https://doi.org/10.1016/j.antiviral.2016.05.003
Widjaja, I., Wicht, O., Luytjes, W., Leenhouts, K., Rottier, P. J. M., van Kuppeveld, F. J. M., Haijema, B. J., & de Haan, C. A. M. (2016). Characterization of epitope-specific anti-RSV antibody responses after natural infection and after vaccination with formalin-inactivated RSV. Journal of Virology, 90(13), 5965-5977. https://doi.org/10.1128/JVI.00235-16
Baggen, J., Thibaut, H. J., Staring, J., Jae, L. T., Liu, Y., Guo, H., Slager, J. J., de Bruin, J. W., van Vliet, A. L. W., Blomen, V. A., Overduin, P., Sheng, J., de Haan, X., de Vries, E., Meijer, A., Rossmann, M. G., Brummelkamp, T. R., & van Kuppeveld, F. J. M. (2016). Enterovirus D68 receptor requirements unveiled by haploid genetics. Proceedings of the National Academy of Sciences of the United States of America, 113(5), 1399-1404. https://doi.org/10.1073/pnas.1524498113
2015
Wetenschappelijke publicaties
Hagemeijer, M., & de Haan, C. A. M. (2015). Studying the dynamics of coronavirus replicative structures. In Coronaviruses: Methods and Protocols (pp. 261-269). (Methods in Molecular Biology; Vol. 1282). Springer. https://doi.org/10.1007/978-1-4939-2438-7_22
Vidalain, P.-O., Jacob, Y., Hagemeijer, M. C., Jones, L. M., Neveu, G., Roussarie, J.-P., Rottier, P. J. M., Tangy, F., & de Haan, C. A. M. (2015). A field-proven yeast two-hybrid protocol used to identify coronavirus-host protein-protein interactions. In H. J. Maier, E. Bickerton, & P. Britton (Eds.), Coronaviruses: Methods and Protocols (pp. 213-229). (Methods in Molecular Biology; Vol. 1282). Springer. https://doi.org/10.1007/978-1-4939-2438-7_18
Cancellieri, M., Bassetto, M., Widjaja, I., van Kuppeveld, F., de Haan, C. A. M., Brancale, A., & de Haan, C. A. M. (2015). In silico structure-based design and synthesis of novel anti-RSV compounds. Antiviral Research, 122, 46-50. https://doi.org/10.1016/j.antiviral.2015.08.003
Widjaja, I., Rigter, A., Jacobino, S., van Kuppeveld, F. J. M., Leenhouts, K., Palomo, C., Melero, J. A., Leusen, J. H. W., Haijema, B. J., Rottier, P. J. M., & de Haan, C. A. M. (2015). Recombinant Soluble Respiratory Syncytial Virus F Protein That Lacks Heptad Repeat B, Contains a GCN4 Trimerization Motif and Is Not Cleaved Displays Prefusion-Like Characteristics. PLoS One, 10(6), Article e0130829. https://doi.org/10.1371/journal.pone.0130829
Habibi, M. S., Jozwik, A., Makris, S., Dunning, J., Paras, A., DeVincenzo, J. P., de Haan, C. A. M., Wrammert, J., Openshaw, P. J. M., Chiu, C., & Mechanisms of Severe Acute Influenza Consortium Investigators (2015). Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus. American Journal of Respiratory and Critical Care Medicine, 191(9), 1040-1049. https://doi.org/10.1164/rccm.201412-2256OC
Ambepitiya Wickramasinghe, I. N., de Vries, R. P., Eggert, A. M., Wandee, N., de Haan, C. A. M., Gröne, A., & Verheije, M. H. (2015). Host tissue and glycan binding specificities of avian viral attachment proteins using novel avian tissue microarrays. PLoS One, 10(6), Article e0128893. https://doi.org/10.1371/journal.pone.0128893
de Vries, E., Guo, H., Dai, M., Rottier, P. J. M., van Kuppeveld, F. J. M., & de Haan, C. A. M. (2015). Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant. Emerging Infectious Diseases, 21(5), 842-846. https://doi.org/10.3201/eid2105.141927
Burkard, C., Verheije, M. H., Haagmans, B. L., van Kuppeveld, F. J., Rottier, P. J. M., Bosch, B.-J., & de Haan, C. A. M. (2015). ATP1A1-mediated Src signaling inhibits coronavirus entry into host cells. Journal of Virology, 89(8), 4434-4448. https://doi.org/10.1128/JVI.03274-14
Populariserende publicaties
Ambepitiya Wickramasinghe, I. N., de Vries, R. P., Eggert, A. M., Wandee, N., de Haan, C. A. M., Gröne, A., & Verheije, M. H. (2015). Host tissue and glycan binding specificities of avian viral attachment proteins using novel avian tissue microarrays: Supplement. (World Biomedical Frontiers). World Biomedical Frontiers. http://biomedfrontiers.org/inf-2015-9-20/
2014
Wetenschappelijke publicaties
Burkard, C., Bloyet, L. M., Wicht, O., Van Kuppeveld, F. J., Rottier, P. J. M., De Haan, C. A. M., & Bosch, B. J. (2014). Dissecting virus entry: Replication-independent analysis of virus binding, internalization, and penetration using minimal complementation of β-galactosidase. PLoS One, 9(7), Article e101762. https://doi.org/10.1371/journal.pone.0101762
Mooney, C. A., Johnson, S. A., 'T Hart, P., Quarles Van Ufford, L., De Haan, C. A. M., Moret, E. E., & Martin, N. I. (2014). Oseltamivir analogues bearing N-substituted guanidines as potent neuraminidase inhibitors. Journal of Medicinal Chemistry, 57(7), 3154-3160. https://doi.org/10.1021/jm401977j
de Vries, R. P., Zhu, X., McBride, R., Rigter, A., Hanson, A., Zhong, G., Hatta, M., Xu, R., Yu, W., Kawaoka, Y., de Haan, C. A. M., Wilson, I. A., & Paulson, J. C. (2014). Hemagglutinin receptor specificity and structural analyses of respiratory droplet-transmissible H5N1 viruses. Journal of Virology, 88(1), 768-73. https://doi.org/10.1128/JVI.02690-13
Wicht, O., Burkard, C., de Haan, C. A. M., van Kuppeveld, F. J. M., Rottier, P. J. M., & Bosch, B. J. (2014). Identification and characterization of a proteolytically primed form of the murine coronavirus spike proteins after fusion with the target cell. Journal of Virology, 88(9), 4943-4952. https://doi.org/10.1128/JVI.03451-13
Oreshkova, N., Cornelissen, L. A. H. M., de Haan, C. A. M., Moormann, R. J. M., & Kortekaas, J. (2014). Evaluation of nonspreading Rift Valley fever virus as a vaccine vector using influenza virus hemagglutinin as a model antigen. Vaccine, 32(41), 5323-9. https://doi.org/10.1016/j.vaccine.2014.07.051
Burkard, C., Verheije, M. H., Wicht, O., van Kasteren, S. I., van Kuppeveld, F. J., Haagmans, B. L., Pelkmans, L., Rottier, P. J. M., Bosch, B. J., & de Haan, C. A. M. (2014). Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway in a Proteolysis-Dependent Manner. PLoS Pathogens, 10(11), Article e1004502. https://doi.org/10.1371/journal.ppat.1004502
Hagemeijer, M. C., Monastyrska, I., Griffith, J., van der Sluijs, P., Voortman, J., van Bergen en Henegouwen, P. M., Vonk, A. M., Rottier, P. J. M., Reggiori, F. M., & De Haan, C. A. M. (2014). Membrane rearrangements mediated by coronavirus nonstructural proteins 3 and 4. Virology, 458-459, 125-135. https://doi.org/10.1016/j.virol.2014.04.027
Overige resultaten
de Haan, C. A. M., Rottier, P., & Haijema, B. J. (2014). Heat-stable respiratory syncytial virus prefusion F protein oligomers and their use in immunological compositions. (Patent No. PCT/EP2014/054804). https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2014140083
2013
Wetenschappelijke publicaties
de Vries, R. P., de Vries, E., Martínez-Romero, C., McBride, R., van Kuppeveld, F. J. M., Rottier, P. J. M., García-Sastre, A., Paulson, J. C., & de Haan, C. A. M. (2013). Evolution of the Hemagglutinin Protein of the New Pandemic H1N1 Influenza Virus: Maintaining Optimal Receptor Binding by Compensatory Substitutions. Journal of Virology, 87(24), 13868-13877. https://doi.org/10.1128/JVI.01955-13
Dortmans, J. C. F. M., Dekkers, J., Ambepitiya Wickramasinghe, I. N., Verheije, M. H., Rottier, P. J. M., van Kuppeveld, F. J. M., de Vries, E., & de Haan, C. A. M. (2013). Adaptation of novel H7N9 influenza A virus to human receptors. Scientific Reports, 3, 3058. https://doi.org/10.1038/srep03058
Monastyrska, I., Ulasli, M., Rottier, P. J. M., Guan, J.-L., Reggiori, F. M., & de Haan, C. A. M. (2013). An autophagy-independent role for LC3 in equine arteritis virus replication. Autophagy, 9(2), 164-174. https://doi.org/10.4161/auto.22743
Rigter, A., Widjaja, I., Versantvoort, H., Coenjaerts, F. E. J., van Roosmalen, M., Leenhouts, K., Rottier, P. J. M., Haijema, B. J., & de Haan, C. A. M. (2013). A Protective and Safe Intranasal RSV Vaccine Based on a Recombinant Prefusion-Like Form of the F Protein Bound to Bacterium-Like Particles. PLoS One, 8(8), e71072. Article e71072. https://doi.org/10.1371/journal.pone.0071072
Martínez-Romero, C., de Vries, E., Belicha-Villanueva, A., Mena, I., Tscherne, D. M., Gillespie, V. L., Albrecht, A. R., de Haan, C. A. M., & García-Sastre, A. (2013). Substitutions T200A and E227A in the hemagglutinin of pandemic 2009 influenza A virus increase lethality but decrease transmission. Journal of Virology, 87(11), 6507-6511. https://doi.org/10.1128/JVI.00262-13
Overige resultaten
Burkard, C., Verheije, M. H., Wicht, O., Rottier, P. J. M., Bosch, B. J., & de Haan, C. A. M. (2013). Murine hepatitis coronavirus is a late penetrating virus that requires a functional HOPS complex for fusion. Poster session presented at 5th European Congress of Virology.
Rigter, A., Widjaja, I., Rottier, P. J. M., Haijema, B. J., & de Haan, C. A. M. (2013). Probing conformational changes of the RSV F protein using conformation-specific antibodies and recombinant soluble F proteins. Poster session presented at XV International Conference on Negative Strand Viruses, Granada, Spain.
2012
Wetenschappelijke publicaties
Snijder, B., Sacher, R., Rämö, P., Liberali, P., Mench, K., Wolfrum, N., Burleigh, L., Scott, C. C., Verheije, M. H., Mercer, J., Moese, S., Heger, T., Theusner, K., Jurgeit, A., Lamparter, D., Balistreri, G., Schelhaas, M., De Haan, C. A. M., Marjomäki, V., ... Pelkmans, L. (2012). Single-cell analysis of population context advances RNAi screening at multiple levels. Molecular Systems Biology [E], 8, 579. https://doi.org/10.1038/msb.2012.9
Ambepitiya Wickramasinghe, I., Promkuntod, N., de Vries, R. P., de Haan, C. A. M., Grone, A., & Verheije, M. H. (2012). Avian Coronavirus Spike Proteins as Tools to Elucidate the Molecular Determinants of IBV-Host Interactions. In Proceedings of the 7th International Symposium on Avian Corona- and Metapneumoviruses and Complicating Pathogens (pp. 110-122). Druckerei Schroder.
de Vries, R. P., Smit, C. H., Bruin, E., Rigter, A., de Vries, E., Cornelissen, L. A. H. M., Eggink, D., Chung, N. P. Y., Moore, J. P., Sanders, R. W., Hokke, C. H., Koopmans, M., Rottier, P. J. M., & de Haan, C. A. M. (2012). Glycan-dependent immunogenicity of recombinant soluble trimeric hemagglutinin. Journal of Virology, 86(21), 11735-11744. https://doi.org/10.1128/JVI.01084-12
de Boer, S. M., Kortekaas, J., de Haan, C. A. M., Rottier, P. J. M., Moormann, R. J. M., & Bosch, B. J. (2012). Heparan sulfate facilitates Rift Valley fever virus entry into the cell. Journal of Virology, 86(24), 13767-13771. https://doi.org/10.1128/JVI.01364-12
Widjaja, I., de Vries, E., Rottier, P. J. M., & de Haan, C. A. M. (2012). Competition between Influenza A Virus Genome Segments. PLoS One, 7(10). https://doi.org/10.1371/journal.pone.0047529
Karnam, G., Rygiel, T. P., Raaben, M., Grinwis, G. C. M., Coenjaerts, F. E. J., Ressing, M. E., Rottier, P. J. M., de Haan, C. A. M., & Meyaard, L. (2012). Receptor Controls Sex-Specific TLR7 Responses to Viral Infection. PLoS Pathogens, 8(5), Article e1002710. https://doi.org/10.1371/journal.ppat.1002710
Hagemeijer, M. C., Vonk, A. M., Monastyrska, I., Rottier, P. J. M., & de Haan, C. A. M. (2012). Visualizing Coronavirus RNA Synthesis in Time by Using Click Chemistry. Journal of Virology, 86 (10), 5808-5816. https://doi.org/10.1128/JVI.07207-11
Bernasconi, R., Galli, C., Noack, J., Bianchi, S., de Haan, C. A. M., Reggiori, F. M., & Molinari, M. (2012). Role of the SEL1L:LC3-I Complex as an ERAD Tuning Receptor in the Mammalian ER. Molecular Cell, 46, 809-819. http://www.ncbi.nlm.nih.gov/pubmed/22633958
van der Schaar, H. M., van der Linden, L., Lanke, K. H. W., Strating, J. R. P. M., Pürstinger, G., de Vries, E., de Haan, C. A. M., Neyts, J., & van Kuppeveld, F. J. M. (2012). Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication. Cell Research, 22(11), 1576-1592. https://doi.org/10.1038/cr.2012.129
Hagemeijer, M. C., Rottier, P. J. M., & de Haan, C. A. M. (2012). Biogenesis and dynamics of the Coronavirus replicative structures. Viruses [E], 4(11), 3245-3269. https://doi.org/10.3390/v4113245
de Vries, E., de Vries, R. P., Wienholts, M. J., Floris, C. E., Jacobs, M. S., Heuvel, A. V. D., Rottier, P. J. M., & de Haan, C. A. M. (2012). Influenza A virus entry into cells lacking sialylated N-glycans. Proceedings of the National Academy of Sciences of the United States of America, 109(19), 7457-7462. https://doi.org/10.1073/pnas.1200987109
Autophagy Consortium, X., de Haan, C. A. M., & Monastyrska, I. (2012). Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 8(4), 455-544. https://doi.org/10.1080/15548627.2020.1797280
Cornelissen, L. A. M. H., de Leeuw, O. S., Tacken, M. G., Klos, H. C., de Vries, R. P., de Boer-Luijtze, E. A., van Zoelen-Bos, D., Rigter, A., Rottier, P. J. M., Moormann, R. J. M., & de Haan, C. A. M. (2012). Protective Efficacy of Newcastle Disease Virus Expressing Soluble Trimeric Hemagglutinin against Highly Pathogenic H5N1 Influenza in Chickens and Mice. PLoS One, 7(8). https://doi.org/10.1371/journal
Overige resultaten
Leenhouts, K., Haijema, B. J., van Roosmalen, M., Rottier, P., de Haan, X., & Bosch, B. J. (2012). Immunogenic compositions in particulate form and methods for producing the same.
2011
Wetenschappelijke publicaties
Reggiori, F., de Haan, C. A. M., & Molinari, M. (2011). Unconventional Use of LC3 by Coronaviruses through the Alleged Subversion of the ERAD Tuning Pathway. Viruses [E], 3(9), 1610-1623. https://doi.org/10.3390/v3091610
https://dspace.library.uu.nl/bitstream/handle/1874/235421/Reggiori%2C%2520F.%2520et%2520al.%2520Viruses%2520%282011%29%2C%25203%2C%25201610-1623.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/235421/Reggiori%2C%2520F.%2520et%2520al.%2520Viruses%2520%282011%29%2C%25203%2C%25201610-1623.pdf?sequence=1
Ambepitiya Wickramasinghe, I. N., de Vries, R. P., Grone, A., de Haan, C. A. M., & Verheije, M. H. (2011). Binding of Avian Coronavirus Spike Proteins to Host Factors Reflects Virus Tropism and Pathogenicity. Journal of Virology, 85(17), 8903-8912. https://doi.org/10.1128/JVI.05112-11
Vogels, M. W., van Balkom, B. W. M., Kaloyanova, D. V., Batenburg, J. J., Heck, A. J. R., Helms, J. B., Rottier, P. J. M., & de Haan, C. A. M. (2011). Identification of host factors involved in coronavirus replication by quantitative proteomics analysis. Proteomics, 11(1), 64-80. https://doi.org/10.1002/pmic.201000309
Ulasli, M., Verheije, M. H., de Haan, C. A. M., & Reggiori, F. M. (2011). Qualitative and quantitative ultrastructural analysis of the membrane rearrangements induced by coronavirus. Cellular Microbiology, 12(6), 844-861. https://doi.org/10.1111/j.1462-5822.2010.01437.x
Hagemeijer, M. C., Ulasli, M., Vonk, A., Reggiori, F. M., Rottier, P. J. M., & de Haan, C. A. M. (2011). Mobility and Interactions of Coronavirus Nonstructural Protein 4. Journal of Virology, 85(9), 4572-4577. https://doi.org/10.1128/JVI.00042-11
Vogels, M. W., van Balkom, B. W. M., Heck, A. J. R., de Haan, C. A. M., Rottier, P. J. M., Batenburg, J. J., Kaloyanova, D. V., & Helms, J. B. (2011). Quantitative proteomic identification of host factors involved in the Salmonella syphimuruim infectin cycle. Proteomics, 11, 4477-4491. https://doi.org/10.1002/pmic.201100224
de Vries, R. P., de Vries, E., Moore, K. S., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2011). Only two residues are responsible for the dramatic difference in receptor binding between swine and new pandemic H1 hemagglutinin. Journal of Biological Chemistry, 286(7), 5868-5875. https://doi.org/10.1074/jbc.M110.193557
https://dspace.library.uu.nl/bitstream/handle/1874/235420/Vries%2C%2520R.P.%2520de%2520et%2520al.%2520J%2520Biol%2520Chem.%2520286%287%29%2C%25205868-75.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/235420/Vries%2C%2520R.P.%2520de%2520et%2520al.%2520J%2520Biol%2520Chem.%2520286%287%29%2C%25205868-75.pdf?sequence=1
de Vries, R. P., Tscherne, D. M., Wienholts, M., Cobos-Jiménez, V., Scholte, F., García-Sastre, A., Rottier, P. J. M., & de Haan, C. A. M. (2011). Dissection of the Influenza A Virus Endocytic Routes Reveals Macropinocytosis as an Alternative Entry Pathway. PLoS Pathogens, 7(3), 1-19. Article e1001329. https://doi.org/10.1371/journal.ppat.1001329
Loeffen, W. L. A., de Vries, R. P., Stockhofe, N., van Zoelen-Bos, D., Maas, R., Koch, G., Moormann, R. J. M., Rottier, P. J. M., & de Haan, C. A. M. (2011). Vaccination with a soluble recombinant hemagglutinin trimer protects pigs against a challenge with pandemic (H1N1) 2009 influenza virus. Vaccine, 29(8), 1545-1550. https://doi.org/10.1016/j.vaccine.2010.12.096
Overige resultaten
Rottier, P. J. M., de Haan, C. A. M., & Bosch, B. J. (2011). Recombinant multimeric influenza proteins. (Patent No. WO 2011/126370).
de Vries, R. P., de Vries, E., Moore, K., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2011). Only two residues are important for the dramatic difference in receptor binding between swine and new pandemic H1 hemagglutinin. Poster session presented at ESWI Conference, Malta.
de Vries, R. P., de Vries, E., Moore, K., Lopez-Cotarelo, P., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2011, Sept 15). Recombinant Soluble Hemagglutinins to study immunogenic and receptor binding properties.
de Vries, E., Tscherne, D. M., Wienholts, M., Cobos-Jiménez, V., Scholte, F., García-Sastre, A., Rottier, P. J. M., & de Haan, C. A. M. (2011). Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an entry pathway. Poster session presented at Keystone Symposium on Patogenesis of Influenza: Virus-Host interactions, Hong Kong.
de Haan, C. A. M., Tscherne, D. M., Wienholts, M., Cobos-Jiménez, V., Scholte, F., García-Sastre, A., & Rottier, P. J. M. (2011). Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an entry pathway. Poster session presented at The Fourth ESWI Influenza Conference, Malta.
de Vries, R. P., de Vries, E., Moore, K., Lopez-Cotarelo, P., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2011, Nov 30). Recombinant Soluble Hemagglutinins to study immunogenic and receptor binding properties.
Monastyrska, I., Ulasli, M., Reggiori, F., Molinari, M., & de Haan, C. A. M. (2011). LC3-I is Abused by Positive-Stranded RNA Viruses for Replication on ER-Derived Vesicles. Poster session presented at Keystone Symposia on Autophagy, Whistler, British Colombia.
de Vries, R. P., de Vries, E., Moore, K., Lopez-Cotarelo, P., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2011, Apr 14). Recombinant Soluble Hemagglutinins to study immunogenic and receptor binding properties.
de Vries, R. P., Smit, C. H., Rigter, A., Cornelissen, L. A. H. M., Eggink, D. W., Sanders, R. W., Hokke, C. H., Rottier, P. J. M., & de Haan, C. A. M. (2011). Glycosylation-dependent immunogenicity of recombinant soluble trimeric hemagglutinin. Poster session presented at Gordons Glycobiology Meeting, Lucca (Barga), Italy.
de Vries, R. P., de Vries, E., Moore, K., Lopez-Cotarelo, P., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2011, Nov 10). Recombinant Soluble Hemagglutinins to study immunogenic and receptor binding properties.
de Vries, R. P., de Vries, E., Moore, K., Lopez-Cotarelo, P., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2011, Oct 4). Recombinant Soluble Hemagglutinins to study immunogenic and receptor binding properties.
2010
Wetenschappelijke publicaties
de Vries, R. P., de Vries, E., Bosch, B. J., de Groot, R. J., Rottier, P. J. M., & de Haan, C. A. M. (2010). The influenza A virus hemagglutinin glycosylation state affects receptor-binding specificity. Virology, 403(1), 17-25. https://doi.org/10.1016/j.virol.2010.03.047
Bosch, B. J., Bodewes, R., de Vries, R. P., Kreijtz, J. H. C. M., Bartelink, W., van Amerongen, G., Rimmelzwaan, G. F., de Haan, C. A. M., Osterhaus, A. D. M. E., & Rottier, P. J. M. (2010). Recombinant soluble, multimeric HA and NA exhibit distinctive types of protection against pandemic swine-origin 2009 A(H1N1) influenza virus infection in ferrets. Journal of Virology, 84(19), 10366-10374. https://doi.org/10.1128/JVI.01035-10
Raaben, M., Posthuma, C. C., Verheije, M. H., te Lintelo, E. G., Kikkert, M., Drijfhout, J. W., Snijder, E. J., Rottier, P. J. M., & de Haan, C. A. M. (2010). The ubiquitin-proteasome system plays an important role during various stages of the coronavirus infection cycle. Journal of Virology, 84(15), 7869-79. https://doi.org/10.1128/JVI.00485-10
Cornelissen, L. A. H. M., de Vries, R. P., de Boer-Luijtze, E. A., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2010). A single immunization with soluble recombinant trimeric hemagglutinin protects chickens against highly pathogenic avian influenza virus H5N1. PLoS One, 5(5), Article e10645. https://doi.org/10.1371/journal.pone.0010645
https://dspace.library.uu.nl/bitstream/handle/1874/202907/Cornelissen%2C%2520L.A.%2520et%2520al.%2520PLoS%2520One%2520%282010%295%285%29%2520e10645.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/202907/Cornelissen%2C%2520L.A.%2520et%2520al.%2520PLoS%2520One%2520%282010%295%285%29%2520e10645.pdf?sequence=1
de Haan, C. A. M., Molinari, M., & Reggiori, F. M. (2010). Autophagy-independent LC3 function in vesicular traffic. Autophagy, 6(7), 994-996.
Reggiori, F., Monastyrska, I., Verheije, M. H., Calì, T., Ulasli, M., Bianchi, S., Bernasconi, R., de Haan, C. A. M., & Molinari, M. (2010). Coronaviruses Hijack the LC3-I-positive EDEMosomes, ER-derived vesicles exporting short-lived ERAD regulators, for replication. Cell Host & Microbe, 7(6), 500-508. https://doi.org/10.1016/j.chom.2010.05.013
Verheije, M. H., Hagemeijer, M. C., Ulasli, M., Reggiori, F., Rottier, P. J. M., Masters, P. S., & de Haan, C. A. M. (2010). The coronavirus nucleocapsid protein is dynamically associated with the replication-transcription complexes. Journal of Virology, 84(21), 11575-11579. https://doi.org/10.1128/JVI.00569-10
Raaben, M., Grinwis, G. C. M., Rottier, P. J. M., & de Haan, C. A. M. (2010). The proteasome inhibitor velcade enhances rather than reduces disease in mouse hepatitis coronavirus-infected mice. Journal of Virology, 84(15), 7880-7885. https://doi.org/10.1128/JVI.00486-10
Widjaja, I., de Vries, E., Tscherne, D. M., García-Sastre, A., Rottier, P. J. M., & de Haan, C. A. M. (2010). Inhibition of the ubiquitin-proteasome system affects influenza A virus infection at a postfusion step. Journal of Virology, 84(18), 9625-9631. https://doi.org/10.1128/jvi.01048-10
Hagemeijer, M. C., Verheije, M. H., Ulasli, M., Shaltiël, I. A., de Vries, L. A., Reggiori, F., Rottier, P. J. M., & de Haan, C. A. M. (2010). Dynamics of coronavirus replication-transcription complexes. Journal of Virology, 84(4), 2134-2149. https://doi.org/10.1128/JVI.01716-09
Overige resultaten
Bosch, B. J., de Vries, R. P., Cornelissen, L., Bodewes, R., Kreijtz, J., Bartelink, W., Osterhaus, A. D., de Haan, C. A. M., & Rottier, P. J. M. (2010). A novel, effective and versatile vaccine approach against influenza: multimeric recombinant HA and NA glycoproteins. Poster session presented at 4th Vaccine and ISV Annual Global Congress, Vienna, Austria.
de Vries, R. P., Bosch, B. J., Cornelissen, L., Bodewes, R., Kreijtz, J., Bartelink, W., Osterhaus, A. D. M. E., de Haan, C. A. M., & Rottier, P. J. M. (2010). A novel, effective and versatile vaccine approach against influenza: multimeric recombinant HA and NA glycoproteins. Poster session presented at Options for the Control of Influenza VII, Hong Kong, China.
de Haan, C. A. M., Hagemeijer, M. C., Ulasli, M., Neveu, G., Lucas-Hourani, M., Tangy, F., Favre, M., Rottier, P. J. M., Reggiori, F., Vidalain, P. O., & Jacob, Y. (2010). Meta-analysis of coronavirus protein interactomes. Poster session presented at The Ninth International Symposium on positive-strand RNA viruses, Atlanta, USA.
de Haan, C. A. M., Bosch, B. J., & Rottier, P. J. M. (2010). Recombinant multimeric influenza proteins. (Patent No. EP10159552.8).
de Vries, R. P., de Vries, E., Moore, K. S., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2010). The H1 hemagglutinins of swine and new pandemic influenza A viruses differ dramatically in their receptor binding properties: identification of the responsible residues. Poster session presented at Options for control of Influenza VI, Hong Kong, china.
2009
Wetenschappelijke publicaties
Raaben, M., Prins, M., Martens, A. C. M., Rottier, P. J. M., & de Haan, C. A. M. (2009). Non-invasive imaging of mouse hepatitis coronavirus infection reveals determinants of viral replication and spread in vivo. Cellular Microbiology, 11(5), 825-841. https://doi.org/10.1111/j.1462-5822.2009.01298.x
Raaben, M., Groot Koerkamp, M. J. A., Rottier, P. J. M., & de Haan, C. A. M. (2009). Type I interferon receptor-independent and -dependent host transcriptional responses to mouse hepatitis coronavirus infection in vivo. BMC Genomics, 10, Article 350. https://doi.org/10.1186/1471-2164-10-350
https://dspace.library.uu.nl/bitstream/handle/1874/39455/Raaben%2C%2520M%2520et%2520al%2520BMC%2520Genomics.%2520Aug%25202009.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/39455/Raaben%2C%2520M%2520et%2520al%2520BMC%2520Genomics.%2520Aug%25202009.pdf?sequence=1
Overige resultaten
Hagemeijer, M. C., Verheije, M. H., Ulasli, M., Shaltiël, I. A., de Vries, L. A., Reggiori, F., Rottier, P. J. M., & de Haan, C. A. M. (2009). Dynamics of Coronavirus Replication-Transcription Complexes. Poster session presented at Joint FEBS – EMBO Advanced Lecture Course, Cargèse, Corsica, France.
2008
Wetenschappelijke publicaties
de Haan, C. A. M., Haijema, B. J., Masters, P. S., & Rottier, P. J. M. (2008). Manipulation of the coronavirus genome using targeted recombination with interspecies chimeric coronaviruses. In D. Cavanagh (Ed.), SARS- and Other Coronaviruses: Laboratory Protocols (pp. 229-236). (Methods in Molecular Biology; Vol. 454). Humana Press. https://doi.org/10.1007/978-1-59745-181-9_17
Bosch, B. J., Rossen, J. W. A., Bartelink, W., Zuurveen, S. J., de Haan, C. A. M., Duquerroy, S., Boucher, C. A. B., & Rottier, P. J. M. (2008). Coronavirus escape from heptad repeat 2 (HR2)-derived peptide entry inhibition as a result of mutations in the HR1 domain of the spike fusion protein. Journal of Virology, 82(5), 2580-2585. https://doi.org/10.1128/JVI.02287-07
Oostra, M., Hagemeijer, M. C., Gent, M., Bekker, C. P. J., te Lintelo, E. G., Rottier, P. J. M., & de Haan, C. A. M. (2008). Topology and Membrane Anchoring of the Coronavirus Replication Complex: Not All Hydrophobic Domains of nsp3 and nsp6 Are Membrane Spanning. Journal of Virology, 82(24), 12392-12405. https://doi.org/10.1128/JVI.01219-08
de Haan, C. A. M., & Reggiori, F. M. (2008). Are nidoviruses hijacking the autophagy machinery? Autophagy, 4(3), 276-279.
Raaben, M., Whitley, P., Bouwmeester, D., Setterquist, R. A., Rottier, P. J. M., & de Haan, C. A. M. (2008). Improved microarray gene expression profiling of virus-infected cells after removal of viral RNA. BMC Genomics, 9, 221. http://www.biomedcentral.com/1471-2164/9/221
de Haan, C. A. M., Haijema, B. J., Schellen, P., Schreur, P. W., te Lintelo, E., Vennema, H., & Rottier, P. J. M. (2008). Cleavage of group 1 coronavirus spike proteins; how furin cleavage is traded off against heparan sulfate binding upon cell culture adaptation. Journal of Virology, 82(12), 6078-6083. https://doi.org/10.1128/JVI.00074-08
Verheije, M. H., Raaben, M., Mari, M., Te Lintelo, E. G., Reggiori, F., van Kuppeveld, F. J. M., Rottier, P. J. M., & de Haan, C. A. M. (2008). Mouse hepatitis coronavirus RNA replication depends on GBF1-mediated ARF1 activation. PLoS Pathogens, 4(6), Article e1000088. https://doi.org/10.1371/journal.ppat.1000088
Overige resultaten
Vogels, M. W., Kaloyanova, D. V., van Balkom, B. W. M., Batenburg, J. J., Helms, J. B., Rottier, P. J. M., & de Haan, C. A. M. (2008). Interactions of intracellular pathogens with the Golgi apparatus.. Poster session presented at The XIth International Symposium on Nidovirus, St. Catherine's College, Oxford, United Kingdom.
2007
Wetenschappelijke publicaties
Eifart, P., Ludwig, K., Bottcher, C., de Haan, C. A. M., Rottier, P. J. M., Korte, T., & Herrmann, A. (2007). The role of endocytosis and low pH in cell entry of the murine hepatitis virus MHV-A59. Journal of Virology, 81(19), 10758-10768.
Raaben, M., Groot Koerkamp, M. J. A., Rottier, P. J. M., & de Haan, C. A. M. (2007). Mouse hepatitis coronavirus replication induces host translational shutoff and mRNA decay, with concomitant formation of stress granules and processing bodies. Cellular Microbiology, 9(9), 2218-2229. https://doi.org/10.1111/j.1462-5822.2007.00951.x
Oostra, M., de Haan, C. A. M., & Rottier, P. J. M. (2007). The 29-nucleotide deletion present in human but not in animal SARS coronaviruses disrupts the functional expression of open reading frame 8. Journal of Virology, 81(24), 13876-13888. https://doi.org/10.1128/JVI.01631-07
Oostra, M., te Lintelo, E. G., Deijs, M., Verheije, M. H., Rottier, P. J. M., & de Haan, C. A. M. (2007). Localization and membrane topology of the coronavirus nonstructural protein 4: involvement of the early secretory pathway in replication. Journal of Virology, 81(22), 12323-12336. https://doi.org/10.1128/JVI.01506-07
van der Meer, F. J. U. M., de Haan, C. A. M., Schuurman, N. M., Haijema, B. J., Peumans, W. J., van Damme, E. J., Delputte, P. L., Balzarini, J., & Egberink, H. F. (2007). Antiviral activity of carbohydrate-binding agents against Nidovirales in cell culture. Antiviral Research, 76(1), 21-29. https://doi.org/10.1016/j.antiviral.2007.04.003
van der Meer, F. J. U. M., de Haan, C. A. M., Schuurman, N. M. P., Haijema, B. J., Verheije, M. H., Bosch, B. J., Balzarini, J., & Egberink, H. F. (2007). The carbohydrate-binding plant lectins and the non-peptidic antibiotic pradimicin A target the glycans of the coronavirus envelope glycoproteins. Journal of Antimicrobial Chemotherapy, 60(4), 741-749. https://doi.org/10.1093/jac/dkm301
Raaben, M., Einerhand, A. W., Taminiau, L. J., van Houdt, M., Bouma, J., Raatgeep, R. H., Buller, H. A., de Haan, C. A. M., & Rossen, J. W. A. (2007). Cyclooxygenase activity is important for efficient replication of mouse hepatitis virus at an early stage of infection. Virology Journal, 4, 55.
https://dspace.library.uu.nl/bitstream/handle/1874/26062/Raaben%2C%2520M.%2520et%2520al%2520J.Virol%25202007%2520Jun%25207%3B4%2520%281%2955..pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/26062/Raaben%2C%2520M.%2520et%2520al%2520J.Virol%25202007%2520Jun%25207%3B4%2520%281%2955..pdf?sequence=1
Overige resultaten
de Haan, C. A. M., Oostra, M., te Lintelo, E. G., Deijs, M., Verheije, M. H., & Rottier, P. J. M. (2007). Membrane topology and subcellular localization of the coronavirus non-structural protein 4.. Poster session presented at RNA Virus Meeting, Washington DC.
Oostra, M., de Haan, C. A. M., & Rottier, P. J. M. (2007). Expression and characterization of the Severe Acute Respiratory Syndrome Coronavirus Orf8-related products which differ between human and animal virus isolates. Poster session presented at RNA Virus Meeting, Washington DC.
Oostra, M., de Haan, C. A. M., & Rottier, P. J. M. (2007). Expression and characterization of the Severe Acute Respiratory Syndrome Coronavirus Orf8-related products which differ between human and animal virus isolates. Poster session presented at FEBS/EMBO advanced lecture course, Cellular and Biology of membranes, Corsica.
2006
Wetenschappelijke publicaties
de Haan, C. A. M., Te Lintelo, E., Li, Z., Raaben, M., Wurdinger, T., Bosch, B. J., & Rottier, P. J. M. (2006). Cooperative involvement of the S1 and S2 subunits of the murine coronavirus spike protein in receptor binding and extended host range. Journal of Virology, 80(22), 10909-10918. https://doi.org/10.1128/JVI.00950-06
Verheije, M. H., Würdinger, T., van Beusechem, V. W., de Haan, C. A. M., Gerritsen, W. R., & Rottier, P. J. M. (2006). Redirecting coronavirus to a nonnative receptor through a virus-encoded targeting adapter. Journal of Virology, 80(3), 1250-1260. https://doi.org/10.1128/JVI.80.3.1250-1260.2006
Würdinger, T., Verheije, M. H., van der Aa, L. M., Bosch, B. J., de Haan, C. A. M., van Beusechem, V. W., Gerritsen, W. R., & Rottier, P. J. M. (2006). Antibody-mediated targeting of viral vectors to the Fc receptor expressed on acute myeloid leukemia cells. Leukemia. Leukemia, 20(12), 2182-2184. https://doi.org/10.1038/sj.leu.2404422
Schramm, B., de Haan, C. A. M., Young, J., Doglio, L., Schleich, S., Reese, C., Popov, A. V., Steffen, W., Schroer, T., & Locker, J. K. (2006). Vaccinia-virus-induced cellular contractility facilitates the subcellular localization of the viral replication sites. Traffic, 7(10), 1352-1367.
Oostra, M., de Haan, C. A. M., de Groot, R. J., & Rottier, P. J. M. (2006). Glycosylation of the severe acute respiratory syndrome coronavirus triple-spanning membrane proteins 3a and M. Journal of Virology, 80(5), 2326-2336. https://doi.org/10.1128/JVI.80.5.2326-2336.2006
van der Meer, F. J. U. M., Schuurman, N. M. P., Balzarini, J., de Haan, C. A. M., Haijema, B. J., & Egberink, H. F. (Accepted/In press). Carbohydrate binding plant lectins targeting the N-glycosylation of the nidovirus envelope. Abstract from ESVV Meeting, Lisbon, Portugal 2006.
Schepis, A., Schramm, B., de Haan, C. A. M., & Locker, J. K. (2006). Vaccinia virus-induced microtubule-dependent cellular rearrangements. Traffic, 7(3), 308-323.
https://dspace.library.uu.nl/bitstream/handle/1874/20211/Schepis%2520et%2520al.%2520Traffic%25202006%25207%283%29%3B%2520308-23.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/20211/Schepis%2520et%2520al.%2520Traffic%25202006%25207%283%29%3B%2520308-23.pdf?sequence=1
de Haan, C. A. M., & Rottier, P. J. M. (2006). Hosting the severe acute respiratory syndrome coronavirus: specific cell factors required for infection. Cellular Microbiology, 8(8), 1211-1218. https://doi.org/10.1111/j.1462-5822.2006.00744.x
2005
Wetenschappelijke publicaties
de Haan, C. A. M., Li, Z., te Lintelo, E., Bosch, B. J., Haijema, B. J., & Rottier, P. J. M. (2005). Murine coronavirus with an extended host range uses heparan sulfate as an entry receptor. Journal of Virology, 79(22), 14451-14456. https://doi.org/10.1128/JVI.79.22.14451-14456.2005
Bosch, B. J., de Haan, C. A. M., Smits, S. L., & Rottier, P. J. M. (2005). Spike protein assembly into the coronavirion: exploring the limits of its sequence requirements. Virology, 334(2), 306-318. https://doi.org/10.1016/j.virol.2005.02.001
Würdinger, T., Verheije, M. H., Raaben, M., Bosch, B. J., de Haan, C. A. M., van Beusechem, V. W., Rottier, P. J. M., & Gerritsen, W. R. (2005). Targeting non-human coronaviruses to human cancer cells using a bispecific single-chain antibody. Gene Therapy, 12(18), 1394-1404. https://doi.org/10.1038/sj.gt.3302535
de Haan, C. A. M., Haijema, B. J., Boss, D., Heuts, F. W., & Rottier, P. J. M. (2005). Coronaviruses as vectors: stability of foreign gene expression. Journal of Virology, 79(20), 12742-12751. https://doi.org/10.1128/JVI.79.20.12742-12751.2005
Würdinger, T., Verheije, M. H., Broen, K., Bosch, B. J., Haijema, B. J., de Haan, C. A. M., van Beusechem, V. W., Gerritsen, W. R., & Rottier, P. J. M. (2005). Soluble receptor-mediated targeting of mouse hepatitis coronavirus to the human epidermal growth factor receptor. Journal of Virology, 79(24), 15314-15322. https://doi.org/10.1128/JVI.79.24.15314-15322.2005
de Haan, C. A. M., & Rottier, P. J. M. (2005). Molecular interactions in the assembly of coronaviruses. Advances in Virus Research, 64, 165-230. https://doi.org/10.1016/S0065-3527(05)64006-7
2004
Wetenschappelijke publicaties
de Haan, C. A. M., Stadler, K., Godeke, G.-J., Bosch, B. J., & Rottier, P. J. M. (2004). Cleavage inhibition of the murine coronavirus spike protein by a furin-like enzyme affects cell-cell but not virus-cell fusion. Journal of Virology, 78(11), 6048-54. https://doi.org/10.1128/JVI.78.11.6048-6054.2004
Bosch, B. J., de Haan, C. A. M., & Rottier, P. J. M. (2004). Coronavirus spike glycoprotein, extended at the carboxy terminus with green fluorescent protein, is assembly competent. Journal of Virology, 78(14), 7369-78. https://doi.org/10.1128/JVI.78.14.7369-7378.2004
Overige resultaten
Rottier, P., de Haan, X., Haijema, B. J., & Bosch, B. J. (2004). Coronavirus-like particles comprising functionally deleted genomes.
Verheije, M. H., Würdinger, T., Raaben, M., Bosch, B. J., van Beusechem, V. W., de Haan, C. A. M., Rottier, P. J. M., & Gerritsen, W. R. (2004). Non-human coronaviruses as potential tool for cancer therapy: selective targeting to and effective eradication of human tumor cells in vitro. Poster session presented at 7th international symposium on positive strand RNA viruses, San Francisco (USA).
2003
Wetenschappelijke publicaties
Bosch, B. J., van der Zee, R., de Haan, C. A. M., & Rottier, P. J. M. (2003). The coronavirus spike protein is a class I virus fusion protein: structural and functional characterization of the fusion core complex. Journal of Virology, 77(16), 8801-11. https://doi.org/10.1128/JVI.77.16.8801-8811.2003
de Haan, C. A. M., van Genne, L., Stoop, J. N., Volders, H., & Rottier, P. J. M. (2003). Coronaviruses as vectors: position dependence of foreign gene expression. Journal of Virology, 77, 11312-11323. https://doi.org/10.1128/JVI.77.21.11312-11323.2003
de Haan, C. A. M., de Wit, M., Kuo, L., Montalto-Morrison, C., Haagmans, B. L., Weiss, S. R., Masters, P. S., & Rottier, P. J. M. (2003). The glycosylation status of the murine hepatitis coronavirus M protein affects the interferogenic capacity of the virus in vitro and its ability to replicate in the liver but not the brain. Virology, 312, 395-406. https://doi.org/10.1016/S0042-6822(03)00235-6
2002
Wetenschappelijke publicaties
de Haan, C. A. M., Volders, H., Koetzner, C. A., Masters, P. S., & Rottier, P. J. M. (2002). Coronaviruses maintain viability despite dramatic rearrangements of the strictly conserved genome organization. Journal of Virology, 76, 12491-12502. https://doi.org/10.1128/JVI.76.24.12491-12502.2002
de Haan, C. A. M., de Wit, M., Kuo, L., Montalto, C., Masters, P. S., Weiss, S. R., & Rottier, P. J. M. (2002). O-glycosylation of the mouse hepatitis coronavirus membrane protein. Virus Research, 82, 77-81. https://doi.org/10.1016/s0168-1702(01)00390-2
de Haan, C. A. M., Masters, P. S., Shen, X., Weiss, S., & Rottier, P. J. M. (2002). The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host. Virology, 296, 177-189. https://doi.org/10.1006/viro.2002.1412
2000
Wetenschappelijke publicaties
de Vries, A. A., Glaser, A. L., Raamsman, M. J., de Haan, C. A., Sarnataro, S., Godeke, G. J., & Rottier, P. J. (2000). Genetic manipulation of equine arteritis virus using full-length cDNA clones: separation of overlapping genes and expression of a foreign epitope. Virology, 270(1), 84-97. https://doi.org/10.1006/viro.2000.0245
Godeke, G. J., de Haan, C. A., Rossen, J. W., Vennema, H., & Rottier, P. J. (2000). Assembly of spikes into coronavirus particles is mediated by the carboxy-terminal domain of the spike protein. Journal of Virology, 74(3), 1566-1571. https://doi.org/10.1128/JVI.74.3.1566-1571.2000
de Haan, C. A. M. (2000). The Corona virus membrane protein: role in assembly. [Doctoral thesis 1 (Research UU / Graduation UU), Utrecht University].
de Haan, C. A. M., Vennema, H., & Rottier, P. J. M. (2000). Assembly of the coronavirus envelope: homotypic interactions between the M proteins. Journal of Virology, 74, 4967-4978. https://doi.org/10.1128/JVI.74.11.4967-4978.2000
1999
Wetenschappelijke publicaties
de Haan, C. A., Smeets, M., Vernooij, F., Vennema, H., & Rottier, P. J. (1999). Mapping of the coronavirus membrane protein domains involved in interaction with the spike protein. Journal of Virology, 73(9), 7441-52.
1998
Wetenschappelijke publicaties
de Haan, C. A., Vennema, H., & Rottier, P. J. (1998). Coronavirus envelope assembly is sensitive to changes in the terminal regions of the viral M protein. In Coronaviruses and Arteriviruses (pp. 367-75). (Advances in Experimental Medicine and Biology; Vol. 440). Springer. https://doi.org/10.1007/978-1-4615-5331-1_48
de Haan, C. A., Kuo, L., Masters, P. S., Vennema, H., & Rottier, P. J. (1998). Coronavirus particle assembly: primary structure requirements of the membrane protein. Journal of Virology, 72(8), 6838-50.
de Haan, C. A., Roestenberg, P., de Wit, M., de Vries, A. A., Nilsson, T., Vennema, H., & Rottier, P. J. (1998). Structural requirements for O-glycosylation of the mouse hepatitis virus membrane protein. Journal of Biological Chemistry, 273(45), 29905-14. https://doi.org/10.1074/jbc.273.45.29905
https://dspace.library.uu.nl/bitstream/handle/1874/395005/29905.full.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/395005/29905.full.pdf?sequence=1