Sleutelpublicaties
Du, W., Guo, H., Nijman, V. S., Doedt, J., van der Vries, E., van der Lee, J., Li, Z., Boons, G.-J., van Kuppeveld, F. J. M., de Vries, E., Matrosovich, M., & de Haan, C. A. M. (2019). The 2nd sialic acid-binding site of influenza A virus neuraminidase is an important determinant of the hemagglutinin-neuraminidase-receptor balance. PLoS Pathogens, 15(6), Article e1007860. [DOI] [Repository]
Du, W., Wolfert, M. A., Peeters, B., van Kuppeveld, F. J. M., Boons, G.-J., de Vries, E., & de Haan, C. A. M. (2020). Mutation of the second sialic acid-binding site of influenza A virus neuraminidase drives compensatory mutations in hemagglutinin. PLoS Pathogens, 16(8), 1-20. Article e1008816. [DOI] [Repository]
de Vries, R. P., Tscherne, D. M., Wienholts, M., Cobos-Jiménez, V., Scholte, F., García-Sastre, A., Rottier, P. J. M., & de Haan, C. A. M. (2011). Dissection of the Influenza A Virus Endocytic Routes Reveals Macropinocytosis as an Alternative Entry Pathway. PLoS Pathogens, 7(3), 1-19. Article e1001329. [DOI] [Repository]
de Vries, E., de Vries, R. P., Wienholts, M. J., Floris, C. E., Jacobs, M. S., Heuvel, A. V. D., Rottier, P. J. M., & de Haan, C. A. M. (2012). Influenza A virus entry into cells lacking sialylated N-glycans. Proceedings of the National Academy of Sciences of the United States of America, 109(19), 7457-7462. [DOI]
Guo, H., Rabouw, H., Slomp, A., Dai, M., van der Vegt, F., van Lent, J. W. M., McBride, R., Paulson, J. C., de Groot, R. J., van Kuppeveld, F. J. M., de Vries, E., & de Haan, C. A. M. (2018). Kinetic analysis of the influenza A virus HA/NA balance reveals contribution of NA to virus-receptor binding and NA-dependent rolling on receptor-containing surfaces. PLoS Pathogens, 14(8), Article e1007233. [DOI] [Repository]
Cornelissen, L. A. H. M., de Vries, R. P., de Boer-Luijtze, E. A., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2010). A single immunization with soluble recombinant trimeric hemagglutinin protects chickens against highly pathogenic avian influenza virus H5N1. PLoS One, 5(5), Article e10645. [DOI] [Repository]
Burkard, C., Verheije, M. H., Wicht, O., van Kasteren, S. I., van Kuppeveld, F. J., Haagmans, B. L., Pelkmans, L., Rottier, P. J. M., Bosch, B. J., & de Haan, C. A. M. (2014). Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway in a Proteolysis-Dependent Manner. PLoS Pathogens, 10(11), Article e1004502. [DOI] [Repository]
Hagemeijer, M. C., Verheije, M. H., Ulasli, M., Shaltiël, I. A., de Vries, L. A., Reggiori, F., Rottier, P. J. M., & de Haan, C. A. M. (2010). Dynamics of coronavirus replication-transcription complexes. Journal of Virology, 84(4), 2134-2149. [DOI] [Repository]
Publicaties
2025
Wetenschappelijke publicaties
Hoornweg, T. E., Schaftenaar, W., IJzer, J., Mulder, M. M. P., Lugtenburg, M., van Beest, A., de Haan, C. A. M., & Rutten, V. P. M. G. (2025). Elevated IL-6, IL-10, and IFN-γ levels in fatal elephant endotheliotropic herpesvirus - hemorrhagic disease cases suggest an excessive proinflammatory cytokine response contributes to pathogenesis. Frontiers in Immunology, 16, Article 1645752. [DOI] [Portal]
Peng, W., Šiborová, M., Wu, X., Du, W., Schulte, D., Pronker, M. F., de Haan, C. A. M., & Snijder, J. (2025). Structural Basis for Postfusion-Specific Binding to the Respiratory Syncytial Virus F Protein by the Canonical Antigenic Site I Antibody 131-2a. ACS Infectious Diseases , 11(8), 2357-2366. [DOI] [Portal]
Wu, X., Luteijn, R. D., Lozano-Andrés, E., Marougka, K., Li, W., Narimatsu, Y., van Kuppeveld, F. J. M., Bosch, B. J., Lebbink, R. J., Vries, E. D., & de Haan, C. A. M. (2025). Identification of β4GALNT2 as an anti-hPIV3 factor through genome-wide CRISPR/Cas9 library screening. Emerging microbes & infections, 14(1), Article 2529895. [DOI] [Portal]
Duijvestijn, M. B. H. M., Schuurman, N. N. M. P., Vernooij, J. C. M., Broekhuizen, M. J., de Bruin, E., Carrière, B. S., van den Brand, J. M. A., Wagenaar, J. A., van Kuppeveld, F. J. M., Egberink, H. F., de Haan, C. A. M., & Verhagen, J. H. (2025). Hunting-training dogs and companion dogs in the Netherlands are frequently exposed to highly pathogenic avian influenza (HPAI H5) and human H1N1 virus, 2021–2023. One Health, 21, Article 101134. [DOI] [Portal]
Liu, M., Wu, X., van de Garde, M. D. B., Narimatsu, Y., van Kuppeveld, F. J. M., Clausen, H., de Haan, C. A. M., & de Vries, E. (2025). Cell-based sialoglycan arrays for directly comparing influenza A virus receptor requirements for binding and infection. iScience, 28(6), Article 112549. [DOI] [Portal]
Swart, I. C., Debski-Antoniak, O. J., Zegar, A., de Bouter, T., Chatziandreou, M., van den Berg, M., Drulyte, I., Pyrc, K., de Haan, C. A. M., Hurdiss, D. L., Bosch, B.-J., & Oliveira, S. (2025). A bivalent spike-targeting nanobody with anti-sarbecovirus activity. Journal of Nanobiotechnology, 23(1), Article 196. [DOI] [Portal]
2024
Wetenschappelijke publicaties
Duijvestijn, M. B. H. M., Schuurman, N. N. M. P., Vernooij, J. C. M., van Leeuwen, M. A. J. M., van den Brand, J. M. A., Wagenaar, J. A., van Kuppeveld, F. J. M., Egberink, H. F., de Haan, C. A. M., & Verhagen, J. H. (2024). Highly pathogenic avian influenza (HPAI) H5 virus exposure in domestic cats and rural stray cats, the Netherlands, October 2020 to June 2023. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 29(44), Article pii=2400326. [DOI] [Portal]
Takehana, K., Hoornweg, T. E., Schaftenaar, W., Rutten, V. P., de Haan, C. A., & Matsuno, K. (2024). Elephant endotheliotropic herpesvirus gB-specific antibody levels in sera of Asian elephants (Elephas maximus) in Japanese zoos. Journal of Veterinary Medical Science, 86(12), 1279-1283. [DOI] [Portal]
Wu, X., Goebbels, M., Debski-Antoniak, O., Marougka, K., Chao, L., Smits, T., Wennekes, T., van Kuppeveld, F. J. M., de Vries, E., & de Haan, C. A. M. (2024). Unraveling dynamics of paramyxovirus-receptor interactions using nanoparticles displaying hemagglutinin-neuraminidase. PLoS Pathogens, 20(7), Article e1012371. [DOI] [Portal]
Pascha, M. N., Ballegeer, M., Roelofs, M. C., Meuris, L., Albulescu, I. C., van Kuppeveld, F. J. M., Hurdiss, D. L., Bosch, B. J., Zeev-Ben-Mordehai, T., Saelens, X., & de Haan, C. A. M. (2024). Nanoparticle display of neuraminidase elicits enhanced antibody responses and protection against influenza A virus challenge. npj Vaccines, 9(1), Article 97. [DOI] [Repository]
Swart, I. C., Van Gelder, W., De Haan, C. A. M., Bosch, B.-J., & Oliveira, S. (2024). Next generation single-domain antibodies against respiratory zoonotic RNA viruses. Frontiers in Molecular Biosciences, 11, Article 1389548. [DOI] [Repository]
Hoornweg, T. E., Schaftenaar, W., Rutten, V. PMG., & Haan, C. D. (2024). Low gH/gL (Sub)Species-Specific Antibody Levels Indicate Elephants at Risk of Fatal Elephant Endotheliotropic Herpesvirus Hemorrhagic Disease. Viruses, 16(2), Article 268. [DOI] [Repository]
Pascha, M. N., Ballegeer, M., Roelofs, M. C., Meuris, L., Albulescu, I. C., Kuppeveld, F. J. M. V., Hurdiss, D. L., Bosch, B.-J., Zeev-Ben-Mordehai, T., Saelens, X., & Haan, C. A. M. D. (2024). Nanoparticle display of neuraminidase elicits enhanced antibody responses and protection against influenza A virus challenge in mice. Research Square. [DOI] [Repository]
Lapierre, L., Roland, J. T., Manning, E. H., Caldwell, C., Glenn, H. L., Vidalain, P.-O., Tangy, F., Hogue, B. G., Haan, C. D., & Goldenring, J. R. (2024). Coronavirus M Protein Trafficking in Epithelial Cells Utilizes a Myosin Vb Splice Variant and Rab10. Cells, 13(2), 1-18. Article 126. [DOI] [Repository]
2023
Wetenschappelijke publicaties
Liu, M., Morewood, R., Yoshisada, R., Pascha, M. N., Hopstaken, A. J. P., Tarcoveanu, E., Poole, D. A., de Haan, C. A. M., Nitsche, C., & Jongkees, S. A. K. (2023). Selective thiazoline peptide cyclisation compatible with mRNA display and efficient synthesis. Chemical Science, 14(38), 10561-10569. [DOI] [Repository]
Wallace, L. E., Vries, E. D., Kuppeveld, F. J. M. V., & Haan, C. A. M. D. (2023). Neuraminidase-dependent entry of influenza A virus is determined by hemagglutinin receptor-binding specificity. Journal of Virology, 97(10), Article e0060223. [DOI] [Repository]
Lakerveld, A. J., Gelderloos, A. T., Schepp, R. M., de Haan, C. A. M., van Binnendijk, R. S., Rots, N. Y., van Beek, J., van Els, C. A. C. M., & van Kasteren, P. B. (2023). Difference in respiratory syncytial virus-specific Fc-mediated antibody effector functions between children and adults. Clinical and Experimental Immunology, 214(1), 79-93. Article uxad101. [DOI] [Repository]
Liu, M., Bakker, A. S., Narimatsu, Y., van Kuppeveld, F. J. M., Clausen, H., de Haan, C. A. M., & de Vries, E. (2023). H3N2 influenza A virus gradually adapts to human-type receptor binding and entry specificity after the start of the 1968 pandemic. Proceedings of the National Academy of Sciences of the United States of America, 120(31), Article e2304992120. [DOI] [Repository]
Liu, M., van Kuppeveld, F. J., de Haan, C. A., & de Vries, E. (2023). Gradual adaptation of animal influenza A viruses to human-type sialic acid receptors. Current Opinion in Virology, 60, 1-15. Article 101314. [DOI] [Repository]
Wu, X., Goebbels, M., Chao, L., Wennekes, T., van Kuppeveld, F. J. M., de Vries, E., & de Haan, C. A. M. (2023). Kinetic analysis of paramyxovirus-sialoglycan receptor interactions reveals virion motility. PLoS Pathogens, 19(3), Article e1011273. [DOI] [Repository]
de Vries, E., & de Haan, C. A. (2023). Letter to the editor: Highly pathogenic influenza A(H5N1) viruses in farmed mink outbreak contain a disrupted second sialic acid binding site in neuraminidase, similar to human influenza A viruses. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 28(7), Article 2300085. [DOI] [Repository]
Liu, M., Yoshisada, R., Amedi, A., Hopstaken, A. J. P., Pascha, M. N., de Haan, C. A. M., Geerke, D. P., Poole, D. A., & Jongkees, S. A. K. (2023). An efficient, site-selective and spontaneous peptide macrocyclisation during in vitro translation. Chemistry-A European Journal, 29(14), 1-11. Article e202203923. [DOI] [Repository]
2022
Wetenschappelijke publicaties
Porbahaie, M., Savelkoul, H. F. J., de Haan, C. A. M., Teodorowicz, M., & van Neerven, R. J. J. (2022). Direct Binding of Bovine IgG-Containing Immune Complexes to Human Monocytes and Their Putative Role in Innate Immune Training. Nutrients, 14(21), Article 4452. [DOI] [Repository]
Liu, M., Huang, L. Z. X., Smits, A. A., Büll, C., Narimatsu, Y., van Kuppeveld, F. J. M., Clausen, H., de Haan, C. A. M., & de Vries, E. (2022). Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions. Nature Communications, 13(1), 1-12. Article 4054. [DOI] [Repository]
van de Ven, K., van Dijken, H., Du, W., de Heij, F., Mouthaan, J., Spijkers, S., van den Brink, S., Roholl, P., de Haan, C. A. M., & de Jonge, J. (2022). Varying Viral Replication and Disease Profiles of H2N2 Influenza in Ferrets Is Associated with Virus Isolate and Inoculation Route. Journal of Virology, 96(14), 1-14. Article e0073222. [DOI] [Repository]
de Vries, E., Guo, H., Du, W., Liu, M., van Kuppeveld, F. J. M., & de Haan, C. A. M. (2022). Quantification of Receptor Association, Dissociation, and NA-Dependent Motility of Influenza A Particles by Biolayer Interferometry. In Glycovirology: Methods and Protocols (pp. 123-140). (Methods in Molecular Biology; Vol. 2556). Humana Press. [DOI] [Repository]
Pascha, M. N., Thijssen, V., Egido, J. E., Linthorst, M. W., van Lanen, J. H., van Dongen, D. A. A., Hopstaken, A. J. P., van Kuppeveld, F. J. M., Snijder, J., de Haan, C. A. M., & Jongkees, S. A. K. (2022). Inhibition of H1 and H5 Influenza A Virus Entry by Diverse Macrocyclic Peptides Targeting the Hemagglutinin Stem Region: ACS Chemical Biology. ACS Chemical Biology, 17(9), 2425-2436. [DOI] [Repository]
Spencer Clinton, J. L., Hoornweg, T., Tan, J., Peng, R., Schaftenaar, W., Rutten, VP., de Haan, X., & Ling, P. D. (2022). EEHV1A glycoprotein B subunit vaccine elicits humoral and cell-mediated immune responses in mice. Vaccine, 40(35), 5131-5140. [DOI] [Repository]
Hoornweg, T. E., Perera, V. P., Karunarathne, R. N. S., Schaftenaar, W., Mahakapuge, T. A. N., Kalupahana, A. W., Rutten, V. P. M. G., & de Haan, C. A. M. (2022). Young elephants in a large herd maintain high levels of elephant endotheliotropic herpesvirus-specific antibodies and do not succumb to fatal haemorrhagic disease. Transboundary and emerging diseases, 69(5), e3379-e3385. [DOI] [Repository]
Wei, X., Du, W., Duca, M., Yu, G., de Vries, E., de Haan, C. A. M., & Pieters, R. J. (2022). Preventing Influenza A Virus Infection by Mixed Inhibition of Neuraminidase and Hemagglutinin by Divalent Inhibitors. Journal of Medicinal Chemistry, 65(10), 7312-7323. [DOI] [Repository]
2021
Wetenschappelijke publicaties
Creytens, S., Pascha, M. N., Ballegeer, M., Saelens, X., & de Haan, C. A. M. (2021). Influenza Neuraminidase Characteristics and Potential as a Vaccine Target. Frontiers in Immunology, 12, 1-19. Article 786617. [DOI] [Repository]
Zaree, P., Torano, J. S., de Haan, C. A. M., Scheltma, R. A., Barendregt, A., Thijssen, V., Yu, G., Flesch, F., & Pieters, R. J. (2021). The assessment of Pseudomonas aeruginosa lectin LecA binding characteristics of divalent galactosides using multiple techniques. Glycobiology, 31(11), 1490-1499. [DOI] [Repository]
Nason, R., Büll, C., Konstantinidi, A., Sun, L., Ye, Z., Halim, A., Du, W., Sørensen, D. M., Durbesson, F., Furukawa, S., Mandel, U., Joshi, H. J., Dworkin, L. A., Hansen, L., David, L., Iverson, T. M., Bensing, B. A., Sullam, P. M., Varki, A., ... Narimatsu, Y. (2021). Display of the human mucinome with defined O-glycans by gene engineered cells. Nature Communications, 12(1), 1-16. Article 4070. [DOI] [Repository]
Klooster, J. P. T., Bol-Schoenmakers, M., van Summeren, K., van Vliet, A. L. W., de Haan, C. A. M., van Kuppeveld, F. J. M., Verkoeijen, S., & Pieters, R. (2021). Enterocytes, fibroblasts and myeloid cells synergize in anti-bacterial and anti-viral pathways with IL22 as the central cytokine. Communications Biology, 4(1), 1-13. Article 631. [DOI] [Repository]
Dai, M., Du, W., Martínez-Romero, C., Leenders, T., Wennekes, T., Rimmelzwaan, G. F., van Kuppeveld, F. J. M., Fouchier, R. A. M., Garcia-Sastre, A., de Vries, E., & de Haan, C. A. M. (2021). Analysis of the Evolution of Pandemic Influenza A(H1N1) Virus Neuraminidase Reveals Entanglement of Different Phenotypic Characteristics. mBio, 12(3), 1-18. Article e00287-21. [DOI] [Repository]
Wallace, L. E., Liu, M., van Kuppeveld, F., de Vries, E., & de Haan, C. A. M. (2021). Respiratory mucus as a virus-host range determinant. Trends in Microbiology, 29(11), 983-992. [DOI] [Repository]
Hoornweg, T. E., Schaftenaar, W., Maurer, G., van den Doel, P. B., Molenaar, F. M., Chamouard-Galante, A., Vercammen, F., Rutten, V. P. M. G., & de Haan, C. A. M. (2021). Elephant Endotheliotropic Herpesvirus Is Omnipresent in Elephants in European Zoos and an Asian Elephant Range Country. Viruses, 13(2), Article 283. [DOI] [Repository]
Du, W., de Vries, E., van Kuppeveld, F. J. M., Matrosovich, M., & de Haan, C. A. M. (2021). Second sialic acid-binding site of influenza A virus neuraminidase: Binding receptors for efficient release. The FEBS journal, 288(19), 5598-5612. [DOI] [Repository]
2020
Wetenschappelijke publicaties
Ghosh, S., Dellibovi-Ragheb, T. A., Kerviel, A., Pak, E., Qiu, Q., Fisher, M., Takvorian, P. M., Bleck, C., Hsu, V. W., Fehr, A. R., Perlman, S., Achar, S. R., Straus, M. R., Whittaker, G. R., de Haan, C. A. M., Kehrl, J., Altan-Bonnet, G., & Altan-Bonnet, N. (2020). β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway. Cell, 183(6), 1520-1535.e14. [DOI] [Repository]
Verdijk, P., van der Plas, J. L., van Brummelen, E. M. J., Jeeninga, R. E., de Haan, C. A. M., Roestenberg, M., Burggraaf, J., & Kamerling, I. M. C. (2020). First-in-human administration of a live-attenuated RSV vaccine lacking the G-protein assessing safety, tolerability, shedding and immunogenicity: a randomized controlled trial. Vaccine, 38(39), 6088-6095. [DOI] [Repository]
Nederend, M., van Stigt, A. H., Jansen, J. H. M., Jacobino, S. R., Brugman, S., de Haan, C. A. M., Bont, L. J., van Neerven, R. J. J., & Leusen, J. H. W. (2020). Bovine IgG Prevents Experimental Infection With RSV and Facilitates Human T Cell Responses to RSV. Frontiers in Immunology, 11, Article 1701. [DOI] [Repository]
Zhao, S., Schuurman, N., Tieke, M., Quist, B., Zwinkels, S., van Kuppeveld, F., de Haan, C. A. M., & Egberink, H. (2020). Serological screening of influenza A virus antibodies in cats and dogs indicates frequent infection with different subtypes. Journal of Clinical Microbiology, 58(11), Article e01689-20. [DOI] [Repository]
Du, W., Wolfert, M. A., Peeters, B., van Kuppeveld, F. J. M., Boons, G.-J., de Vries, E., & de Haan, C. A. M. (2020). Mutation of the second sialic acid-binding site of influenza A virus neuraminidase drives compensatory mutations in hemagglutinin. PLoS Pathogens, 16(8), 1-20. Article e1008816. [DOI] [Repository]
Peng, L., Du, W., Balhuizen, M. D., Haagsman, H. P., de Haan, C. A. M., & Veldhuizen, E. J. A. (2020). Antiviral Activity of Chicken Cathelicidin B1 Against Influenza A Virus. Frontiers in Microbiology, 11, Article 426. [DOI] [Repository]
van Erp, E. A., Lakerveld, A. J., de Graaf, E., Larsen, M. D., Schepp, R. M., Hipgrave Ederveen, A. L., Ahout, I. M., de Haan, C. A., Wuhrer, M., Luytjes, W., Ferwerda, G., Vidarsson, G., & van Kasteren, P. B. (2020). Natural killer cell activation by respiratory syncytial virus-specific antibodies is decreased in infants with severe respiratory infections and correlates with Fc-glycosylation. Clinical & translational immunology, 9(2), Article e1112. [DOI] [Repository]
Cong, Y., Ulasli, M., Schepers, H., Mauthe, M., V'kovski, P., Kriegenburg, F., Thiel, V., de Haan, C. A. M., & Reggiori, F. (2020). Nucleocapsid protein recruitment to replication-transcription complexes plays a crucial role in coronaviral life cycle. Journal of Virology, 94(4), Article e01925-19. [DOI] [Repository]
de Vries, E., Du, W., Guo, H., & de Haan, C. A. M. (2020). Influenza A Virus Hemagglutinin-Neuraminidase-Receptor Balance: Preserving Virus Motility. Trends in Microbiology, 28(1), 57-67. [DOI] [Repository]
2019
Wetenschappelijke publicaties
Schepp, R. M., de Haan, C. A. M., Wilkins, D., Layman, H., Graham, B. S., Esser, M. T., & Berbers, G. A. M. (2019). Development and Standardization of a High-Throughput Multiplex Immunoassay for the Simultaneous Quantification of Specific Antibodies to Five Respiratory Syncytial Virus Proteins. mSphere, 4(2), Article e00236-19. [DOI] [Repository]
Du, W., Guo, H., Nijman, V. S., Doedt, J., van der Vries, E., van der Lee, J., Li, Z., Boons, G.-J., van Kuppeveld, F. J. M., de Vries, E., Matrosovich, M., & de Haan, C. A. M. (2019). The 2nd sialic acid-binding site of influenza A virus neuraminidase is an important determinant of the hemagglutinin-neuraminidase-receptor balance. PLoS Pathogens, 15(6), Article e1007860. [DOI] [Repository]
Lu, W., Du, W., Somovilla, V. J., Yu, G., Haksar, D., de Vries, E., Boons, G.-J., de Vries, R. P., de Haan, C. A. M., & Pieters, R. J. (2019). Enhanced Inhibition of Influenza A Virus Adhesion by Di- and Trivalent Hemagglutinin Inhibitors. Journal of Medicinal Chemistry, 62(13), 6398-6404. [DOI] [Repository]
Mazur, N. I., Horsley, N., Englund, J. A., Nederend, M., Magaret, A., Kumar, A., Jacobino, S. R., de Haan, C. A. M., Khatry, S. K., LeClerq, S. C., Steinhoff, M. C., Tielsch, J. M., Katz, J., Graham, B. S., Bont, L. J., Leusen, J. H. W., & Chu, H. Y. (2019). Breast milk prefusion F Immunoglobulin G as a correlate of protection against respiratory syncytial virus acute respiratory illness. Journal of Infectious Diseases, 219(1), 59-67. [DOI] [Repository]
2018
Wetenschappelijke publicaties
Dong, W., Bhide, Y., Sicca, F., Meijerhof, T., Guilfoyle, K., Engelhardt, O. G., Boon, L., de Haan, C. A. M., Carnell, G., Temperton, N., de Vries-Idema, J., Kelvin, D., & Huckriede, A. (2018). Cross-Protective Immune Responses Induced by Sequential Influenza Virus Infection and by Sequential Vaccination With Inactivated Influenza Vaccines. Frontiers in Immunology, 9, Article 2312. [DOI] [Repository]
Tomar, J., Biel, C., de Haan, C. A. M., Rottier, P. J. M., Petrovsky, N., Frijlink, H. W., Huckriede, A., Hinrichs, W. L. J., & Peeters, B. (2018). Passive inhalation of dry powder influenza vaccine formulations completely protects chickens against H5N1 lethal viral challenge. European Journal of Pharmaceutics and Biopharmaceutics, 133, 85-95. [DOI] [Repository]
Du, W., Dai, M., Li, Z., Boons, G.-J., Peeters, B., van Kuppeveld, F. J. M., de Vries, E., & de Haan, C. A. M. (2018). Substrate binding by the 2 sialic acid-binding site of influenza A virus N1 neuraminidase contributes to enzymatic activity. Journal of Virology, 92(20), Article e01243-18. [DOI] [Repository]
Guo, H., Rabouw, H., Slomp, A., Dai, M., van der Vegt, F., van Lent, J. W. M., McBride, R., Paulson, J. C., de Groot, R. J., van Kuppeveld, F. J. M., de Vries, E., & de Haan, C. A. M. (2018). Kinetic analysis of the influenza A virus HA/NA balance reveals contribution of NA to virus-receptor binding and NA-dependent rolling on receptor-containing surfaces. PLoS Pathogens, 14(8), Article e1007233. [DOI] [Repository]
Baggen, J., Hurdiss, D. L., Zocher, G., Mistry, N., Roberts, R. W., Slager, J. J., Guo, H., van Vliet, A. L. W., Wahedi, M., Benschop, K., Duizer, E., de Haan, C. A. M., de Vries, E., Casasnovas, J. M., de Groot, R. J., Arnberg, N., Stehle, T., Ranson, N. A., Thibaut, H. J., & van Kuppeveld, F. J. M. (2018). Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus. Proceedings of the National Academy of Sciences of the United States of America, 115(2), 397-402. [DOI] [Repository]
Job, E. R., Schotsaert, M., Ibañez, L. I., de Smet, A., Ysenbaert, T., Roose, K., Dai, M., de Haan, C. A. M., Kleanthous, H., Vogel, T. U., & Saelens, X. (2018). Antibodies directed towards neuraminidase N1 control disease in a mouse model of influenza. Journal of Virology, 92(4), Article e01584-17. [DOI] [Repository]
2017
Wetenschappelijke publicaties
Li, W., Hulswit, R. J. G., Widjaja, I., Raj, V. S., McBride, R., Peng, W., Widagdo, W., Tortorici, M. A., van Dieren, B., Lang, Y., van Lent, J. W. M., Paulson, J. C., de Haan, C. A. M., de Groot, R. J., van Kuppeveld, F. J. M., Haagmans, B. L., & Bosch, B.-J. (2017). Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein. Proceedings of the National Academy of Sciences of the United States of America, 114(40), E8508-E8517. [DOI] [Repository]
Cong, Y., Kriegenburg, F., de Haan, C. A. M., & Reggiori, F. (2017). Coronavirus nucleocapsid proteins assemble constitutively in high molecular oligomers. Scientific Reports, 7(1), Article 5740. [DOI] [Repository]
van Erp, E. A., van Kasteren, P. B., Guichelaar, T., Ahout, I. M. L., de Haan, C. A. M., Luytjes, W., Ferwerda, G., & Wicht, O. (2017). In vitro enhancement of RSV infection by maternal antibodies does not explain disease severity in infants. Journal of Virology, 91(21), Article e00851-17 . [DOI] [Repository]
de Vries, R. P., Peng, W., Grant, O. C., Thompson, A. J., Zhu, X., Bouwman, K. M., de la Pena, A. T. T., van Breemen, M. J., Ambepitiya Wickramasinghe, I. N., de Haan, C. A. M., Yu, W., McBride, R., Sanders, R. W., Woods, R. J., Verheije, M. H., Wilson, I. A., & Paulson, J. C. (2017). Three mutations switch H7N9 influenza to human-type receptor specificity. PLoS Pathogens, 13(6), Article e1006390. [DOI] [Repository]
Dai, M., McBride, R., Dortmans, J. C. F. M., Peng, W., Bakkers, M. J. G., de Groot, R. J., van Kuppeveld, F. J. M., Paulson, J. C., de Vries, E., & de Haan, C. A. M. (2017). Mutation of the 2(nd) Sialic Acid-Binding Site Resulting in Reduced Neuraminidase Activity Preceded Emergence of H7N9 Influenza A Virus. Journal of Virology, 91(9), Article e00049-17. [DOI] [Repository]
Jans, J., Wicht, O., Widjaja, I., Ahout, I. M. L., de Groot, R., Guichelaar, T., Luytjes, W., de Jonge, M. I., de Haan, C. A. M., & Ferwerda, G. (2017). Characteristics of RSV-Specific Maternal Antibodies in Plasma of Hospitalized, Acute RSV Patients under Three Months of Age. PLoS One, 12(1), Article e0170877. [DOI] [Repository]
Peeters, B., Reemers, S., Dortmans, J., de Vries, E., de Jong, M., van de Zande, S., Rottier, P. J. M., & de Haan, C. A. M. (2017). Genetic versus antigenic differences among highly pathogenic H5N1 avian influenza A viruses: Consequences for vaccine strain selection. Virology, 503, 83-93. [DOI] [Repository]
Parsons, L. M., An, Y., de Vries, R. P., de Haan, C. A. M., & Cipollo, J. F. (2017). Glycosylation Characterization of an Influenza H5N7 Hemagglutinin Series with Engineered Glycosylation Patterns: Implications for Structure-Function Relationships. Journal of Proteome Research, 16(2), 398–412. [DOI] [Repository]
Guo, H., de Vries, E., McBride, R., Dekkers, J., Bouwman, K. M., Nycholat, C., Verheije, M. H., Paulson, J. C., van Kuppeveld, F. J. M., & de Haan, C. A. M. (2017). Highly Pathogenic Influenza A(H5Nx) Viruses with Altered H5 Receptor-Binding Specificity. Emerging Infectious Diseases, 23(2). [DOI] [Repository]
2016
Wetenschappelijke publicaties
Hulswit, R. J. G., de Haan, C. A. M., & Bosch, B.-J. (2016). Coronavirus Spike Protein and Tropism Changes. Advances in Virus Research, 96, 29-57. [DOI] [Repository]
Mauthe, M., Langereis, M., Jung, J., Zhou, X., Jones, A., Omta, W., Tooze, S. A., Stork, B., Paludan, S. R., Ahola, T., Egan, D., Behrends, C., Mokry, M., de Haan, X., van Kuppeveld, F., & Reggiori, F. (2016). An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication. Journal of Cell Biology, 214(5), 619-635. [DOI] [Repository]
Dai, M., Guo, H., Dortmans, J., Dekkers, J., Nordholm, J., Daniels, R., van Kuppeveld, F. J. M., de Vries, E., & de Haan, C. A. M. (2016). Identification of residues that affect oligomerization and/or enzymatic activity of influenza virus H5N1 neuraminidase proteins. Journal of Virology, 90(20), 9457-9470. [DOI] [Repository]
van Mechelen, L., Luytjes, W., de Haan, C. A. M., & Wicht, O. (2016). RSV neutralization by palivizumab, but not by monoclonal antibodies targeting other epitopes, is augmented by Fc gamma receptors. Antiviral Research, 132, 1-5. [DOI] [Repository]
Widjaja, I., Wicht, O., Luytjes, W., Leenhouts, K., Rottier, P. J. M., van Kuppeveld, F. J. M., Haijema, B. J., & de Haan, C. A. M. (2016). Characterization of epitope-specific anti-RSV antibody responses after natural infection and after vaccination with formalin-inactivated RSV. Journal of Virology, 90(13), 5965-5977. [DOI] [Repository]
Baggen, J., Thibaut, H. J., Staring, J., Jae, L. T., Liu, Y., Guo, H., Slager, J. J., de Bruin, J. W., van Vliet, A. L. W., Blomen, V. A., Overduin, P., Sheng, J., de Haan, X., de Vries, E., Meijer, A., Rossmann, M. G., Brummelkamp, T. R., & van Kuppeveld, F. J. M. (2016). Enterovirus D68 receptor requirements unveiled by haploid genetics. Proceedings of the National Academy of Sciences of the United States of America, 113(5), 1399-1404. [DOI] [Repository]
2015
Wetenschappelijke publicaties
Hagemeijer, M., & de Haan, C. A. M. (2015). Studying the Dynamics of Coronavirus Replicative Structures. In Coronaviruses: Methods and Protocols (1 ed., pp. 261-269). (Methods in Molecular Biology; Vol. 1282). Humana Press. [DOI] [Repository]
Vidalain, P.-O., Jacob, Y., Hagemeijer, M. C., Jones, L. M., Neveu, G., Roussarie, J.-P., Rottier, P. J. M., Tangy, F., & de Haan, C. A. M. (2015). A field-proven yeast two-hybrid protocol used to identify coronavirus-host protein-protein interactions. In H. J. Maier, E. Bickerton, & P. Britton (Eds.), Coronaviruses: Methods and Protocols (pp. 213-229). (Methods in Molecular Biology; Vol. 1282). Springer. [DOI] [Repository]
Cancellieri, M., Bassetto, M., Widjaja, I., van Kuppeveld, F., de Haan, C. A. M., Brancale, A., & de Haan, C. A. M. (2015). In silico structure-based design and synthesis of novel anti-RSV compounds. Antiviral Research, 122, 46-50. [DOI] [Repository]
Widjaja, I., Rigter, A., Jacobino, S., van Kuppeveld, F. J. M., Leenhouts, K., Palomo, C., Melero, J. A., Leusen, J. H. W., Haijema, B. J., Rottier, P. J. M., & de Haan, C. A. M. (2015). Recombinant Soluble Respiratory Syncytial Virus F Protein That Lacks Heptad Repeat B, Contains a GCN4 Trimerization Motif and Is Not Cleaved Displays Prefusion-Like Characteristics. PLoS One, 10(6), Article e0130829. [DOI] [Repository]
Habibi, M. S., Jozwik, A., Makris, S., Dunning, J., Paras, A., DeVincenzo, J. P., de Haan, C. A. M., Wrammert, J., Openshaw, P. J. M., Chiu, C., & Mechanisms of Severe Acute Influenza Consortium Investigators (2015). Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus. American Journal of Respiratory and Critical Care Medicine, 191(9), 1040-1049. [DOI] [Repository]
Ambepitiya Wickramasinghe, I. N., de Vries, R. P., Eggert, A. M., Wandee, N., de Haan, C. A. M., Gröne, A., & Verheije, M. H. (2015). Host tissue and glycan binding specificities of avian viral attachment proteins using novel avian tissue microarrays. PLoS One, 10(6), Article e0128893. [DOI] [Repository]
de Vries, E., Guo, H., Dai, M., Rottier, P. J. M., van Kuppeveld, F. J. M., & de Haan, C. A. M. (2015). Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant. Emerging Infectious Diseases, 21(5), 842-846. [DOI] [Repository]
Burkard, C., Verheije, M. H., Haagmans, B. L., van Kuppeveld, F. J., Rottier, P. J. M., Bosch, B.-J., & de Haan, C. A. M. (2015). ATP1A1-mediated Src signaling inhibits coronavirus entry into host cells. Journal of Virology, 89(8), 4434-4448. [DOI] [Repository]
Populariserende publicaties
Ambepitiya Wickramasinghe, I. N., de Vries, R. P., Eggert, A. M., Wandee, N., de Haan, C. A. M., Gröne, A., & Verheije, M. H. (2015). Host tissue and glycan binding specificities of avian viral attachment proteins using novel avian tissue microarrays: Supplement. (World Biomedical Frontiers). World Biomedical Frontiers. http://biomedfrontiers.org/inf-2015-9-20/
2014
Wetenschappelijke publicaties
Burkard, C., Bloyet, L. M., Wicht, O., Van Kuppeveld, F. J., Rottier, P. J. M., De Haan, C. A. M., & Bosch, B. J. (2014). Dissecting virus entry: Replication-independent analysis of virus binding, internalization, and penetration using minimal complementation of β-galactosidase. PLoS One, 9(7), Article e101762. [DOI] [Repository]
Mooney, C. A., Johnson, S. A., 'T Hart, P., Quarles Van Ufford, L., De Haan, C. A. M., Moret, E. E., & Martin, N. I. (2014). Oseltamivir analogues bearing N-substituted guanidines as potent neuraminidase inhibitors. Journal of Medicinal Chemistry, 57(7), 3154-3160. [DOI]
de Vries, R. P., Zhu, X., McBride, R., Rigter, A., Hanson, A., Zhong, G., Hatta, M., Xu, R., Yu, W., Kawaoka, Y., de Haan, C. A. M., Wilson, I. A., & Paulson, J. C. (2014). Hemagglutinin receptor specificity and structural analyses of respiratory droplet-transmissible H5N1 viruses. Journal of Virology, 88(1), 768-73. [DOI]
Wicht, O., Burkard, C., de Haan, C. A. M., van Kuppeveld, F. J. M., Rottier, P. J. M., & Bosch, B. J. (2014). Identification and characterization of a proteolytically primed form of the murine coronavirus spike proteins after fusion with the target cell. Journal of Virology, 88(9), 4943-4952. [DOI] [Repository]
Oreshkova, N., Cornelissen, L. A. H. M., de Haan, C. A. M., Moormann, R. J. M., & Kortekaas, J. (2014). Evaluation of nonspreading Rift Valley fever virus as a vaccine vector using influenza virus hemagglutinin as a model antigen. Vaccine, 32(41), 5323-9. [DOI]
Burkard, C., Verheije, M. H., Wicht, O., van Kasteren, S. I., van Kuppeveld, F. J., Haagmans, B. L., Pelkmans, L., Rottier, P. J. M., Bosch, B. J., & de Haan, C. A. M. (2014). Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway in a Proteolysis-Dependent Manner. PLoS Pathogens, 10(11), Article e1004502. [DOI] [Repository]
Hagemeijer, M. C., Monastyrska, I., Griffith, J., van der Sluijs, P., Voortman, J., van Bergen en Henegouwen, P. M., Vonk, A. M., Rottier, P. J. M., Reggiori, F. M., & De Haan, C. A. M. (2014). Membrane rearrangements mediated by coronavirus nonstructural proteins 3 and 4. Virology, 458-459, 125-135. [DOI] [Repository]
Overige resultaten
de Haan, C. A. M., Rottier, P., & Haijema, B. J. (2014). Heat-stable respiratory syncytial virus prefusion F protein oligomers and their use in immunological compositions. (Patent No. PCT/EP2014/054804). https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2014140083
2013
Wetenschappelijke publicaties
de Vries, R. P., de Vries, E., Martínez-Romero, C., McBride, R., van Kuppeveld, F. J. M., Rottier, P. J. M., García-Sastre, A., Paulson, J. C., & de Haan, C. A. M. (2013). Evolution of the Hemagglutinin Protein of the New Pandemic H1N1 Influenza Virus: Maintaining Optimal Receptor Binding by Compensatory Substitutions. Journal of Virology, 87(24), 13868-13877. [DOI] [Repository]
Dortmans, J. C. F. M., Dekkers, J., Ambepitiya Wickramasinghe, I. N., Verheije, M. H., Rottier, P. J. M., van Kuppeveld, F. J. M., de Vries, E., & de Haan, C. A. M. (2013). Adaptation of novel H7N9 influenza A virus to human receptors. Scientific Reports, 3, 3058. [DOI] [Repository]
Monastyrska, I., Ulasli, M., Rottier, P. J. M., Guan, J.-L., Reggiori, F. M., & de Haan, C. A. M. (2013). An autophagy-independent role for LC3 in equine arteritis virus replication. Autophagy, 9(2), 164-174. [DOI]
Rigter, A., Widjaja, I., Versantvoort, H., Coenjaerts, F. E. J., van Roosmalen, M., Leenhouts, K., Rottier, P. J. M., Haijema, B. J., & de Haan, C. A. M. (2013). A Protective and Safe Intranasal RSV Vaccine Based on a Recombinant Prefusion-Like Form of the F Protein Bound to Bacterium-Like Particles. PLoS One, 8(8), e71072. Article e71072. [DOI] [Repository]
Martínez-Romero, C., de Vries, E., Belicha-Villanueva, A., Mena, I., Tscherne, D. M., Gillespie, V. L., Albrecht, A. R., de Haan, C. A. M., & García-Sastre, A. (2013). Substitutions T200A and E227A in the hemagglutinin of pandemic 2009 influenza A virus increase lethality but decrease transmission. Journal of Virology, 87(11), 6507-6511. [DOI] [Repository]
Overige resultaten
Burkard, C., Verheije, M. H., Wicht, O., Rottier, P. J. M., Bosch, B. J., & de Haan, C. A. M. (2013). Murine hepatitis coronavirus is a late penetrating virus that requires a functional HOPS complex for fusion. Poster session presented at 5th European Congress of Virology.
Rigter, A., Widjaja, I., Rottier, P. J. M., Haijema, B. J., & de Haan, C. A. M. (2013). Probing conformational changes of the RSV F protein using conformation-specific antibodies and recombinant soluble F proteins. Poster session presented at XV International Conference on Negative Strand Viruses, Granada, Spain.
2012
Wetenschappelijke publicaties
Snijder, B., Sacher, R., Rämö, P., Liberali, P., Mench, K., Wolfrum, N., Burleigh, L., Scott, C. C., Verheije, M. H., Mercer, J., Moese, S., Heger, T., Theusner, K., Jurgeit, A., Lamparter, D., Balistreri, G., Schelhaas, M., De Haan, C. A. M., Marjomäki, V., ... Pelkmans, L. (2012). Single-cell analysis of population context advances RNAi screening at multiple levels. Molecular Systems Biology [E], 8, 579. [DOI]
Ambepitiya Wickramasinghe, I., Promkuntod, N., de Vries, R. P., de Haan, C. A. M., Grone, A., & Verheije, M. H. (2012). Avian Coronavirus Spike Proteins as Tools to Elucidate the Molecular Determinants of IBV-Host Interactions. In Proceedings of the 7th International Symposium on Avian Corona- and Metapneumoviruses and Complicating Pathogens (pp. 110-122). Druckerei Schroder.
de Vries, R. P., Smit, C. H., Bruin, E., Rigter, A., de Vries, E., Cornelissen, L. A. H. M., Eggink, D., Chung, N. P. Y., Moore, J. P., Sanders, R. W., Hokke, C. H., Koopmans, M., Rottier, P. J. M., & de Haan, C. A. M. (2012). Glycan-dependent immunogenicity of recombinant soluble trimeric hemagglutinin. Journal of Virology, 86(21), 11735-11744. [DOI]
de Boer, S. M., Kortekaas, J., de Haan, C. A. M., Rottier, P. J. M., Moormann, R. J. M., & Bosch, B. J. (2012). Heparan sulfate facilitates Rift Valley fever virus entry into the cell. Journal of Virology, 86(24), 13767-13771. [DOI] [Repository]
Widjaja, I., de Vries, E., Rottier, P. J. M., & de Haan, C. A. M. (2012). Competition between Influenza A Virus Genome Segments. PLoS One, 7(10). [DOI] [Repository]
Karnam, G., Rygiel, T. P., Raaben, M., Grinwis, G. C. M., Coenjaerts, F. E. J., Ressing, M. E., Rottier, P. J. M., de Haan, C. A. M., & Meyaard, L. (2012). Receptor Controls Sex-Specific TLR7 Responses to Viral Infection. PLoS Pathogens, 8(5), Article e1002710. [DOI] [Repository]
Hagemeijer, M. C., Vonk, A. M., Monastyrska, I., Rottier, P. J. M., & de Haan, C. A. M. (2012). Visualizing Coronavirus RNA Synthesis in Time by Using Click Chemistry. Journal of Virology, 86 (10), 5808-5816. [DOI] [Repository]
Bernasconi, R., Galli, C., Noack, J., Bianchi, S., de Haan, C. A. M., Reggiori, F. M., & Molinari, M. (2012). Role of the SEL1L:LC3-I Complex as an ERAD Tuning Receptor in the Mammalian ER. Molecular Cell, 46, 809-819. http://www.ncbi.nlm.nih.gov/pubmed/22633958
van der Schaar, H. M., van der Linden, L., Lanke, K. H. W., Strating, J. R. P. M., Pürstinger, G., de Vries, E., de Haan, C. A. M., Neyts, J., & van Kuppeveld, F. J. M. (2012). Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication. Cell Research, 22(11), 1576-1592. [DOI]
Hagemeijer, M. C., Rottier, P. J. M., & de Haan, C. A. M. (2012). Biogenesis and dynamics of the Coronavirus replicative structures. Viruses [E], 4(11), 3245-3269. [DOI] [Repository]
de Vries, E., de Vries, R. P., Wienholts, M. J., Floris, C. E., Jacobs, M. S., Heuvel, A. V. D., Rottier, P. J. M., & de Haan, C. A. M. (2012). Influenza A virus entry into cells lacking sialylated N-glycans. Proceedings of the National Academy of Sciences of the United States of America, 109(19), 7457-7462. [DOI]
Autophagy Consortium, X., de Haan, C. A. M., & Monastyrska, I. (2012). Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 8(4), 455-544. [DOI]
Cornelissen, L. A. M. H., de Leeuw, O. S., Tacken, M. G., Klos, H. C., de Vries, R. P., de Boer-Luijtze, E. A., van Zoelen-Bos, D., Rigter, A., Rottier, P. J. M., Moormann, R. J. M., & de Haan, C. A. M. (2012). Protective Efficacy of Newcastle Disease Virus Expressing Soluble Trimeric Hemagglutinin against Highly Pathogenic H5N1 Influenza in Chickens and Mice. PLoS One, 7(8). [DOI] [Repository]
Overige resultaten
Leenhouts, K., Haijema, B. J., van Roosmalen, M., Rottier, P., de Haan, X., & Bosch, B. J. (2012). Immunogenic compositions in particulate form and methods for producing the same.
2011
Wetenschappelijke publicaties
Reggiori, F., de Haan, C. A. M., & Molinari, M. (2011). Unconventional Use of LC3 by Coronaviruses through the Alleged Subversion of the ERAD Tuning Pathway. Viruses [E], 3(9), 1610-1623. [DOI] [Repository]
Ambepitiya Wickramasinghe, I. N., de Vries, R. P., Grone, A., de Haan, C. A. M., & Verheije, M. H. (2011). Binding of Avian Coronavirus Spike Proteins to Host Factors Reflects Virus Tropism and Pathogenicity. Journal of Virology, 85(17), 8903-8912. [DOI]
Vogels, M. W., van Balkom, B. W. M., Kaloyanova, D. V., Batenburg, J. J., Heck, A. J. R., Helms, J. B., Rottier, P. J. M., & de Haan, C. A. M. (2011). Identification of host factors involved in coronavirus replication by quantitative proteomics analysis. Proteomics, 11(1), 64-80. [DOI]
Ulasli, M., Verheije, M. H., de Haan, C. A. M., & Reggiori, F. M. (2011). Qualitative and quantitative ultrastructural analysis of the membrane rearrangements induced by coronavirus. Cellular Microbiology, 12(6), 844-861. [DOI]
Hagemeijer, M. C., Ulasli, M., Vonk, A., Reggiori, F. M., Rottier, P. J. M., & de Haan, C. A. M. (2011). Mobility and Interactions of Coronavirus Nonstructural Protein 4. Journal of Virology, 85(9), 4572-4577. [DOI]
Vogels, M. W., van Balkom, B. W. M., Heck, A. J. R., de Haan, C. A. M., Rottier, P. J. M., Batenburg, J. J., Kaloyanova, D. V., & Helms, J. B. (2011). Quantitative proteomic identification of host factors involved in the Salmonella syphimuruim infectin cycle. Proteomics, 11, 4477-4491. [DOI]
de Vries, R. P., de Vries, E., Moore, K. S., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2011). Only two residues are responsible for the dramatic difference in receptor binding between swine and new pandemic H1 hemagglutinin. Journal of Biological Chemistry, 286(7), 5868-5875. [DOI] [Repository]
de Vries, R. P., Tscherne, D. M., Wienholts, M., Cobos-Jiménez, V., Scholte, F., García-Sastre, A., Rottier, P. J. M., & de Haan, C. A. M. (2011). Dissection of the Influenza A Virus Endocytic Routes Reveals Macropinocytosis as an Alternative Entry Pathway. PLoS Pathogens, 7(3), 1-19. Article e1001329. [DOI] [Repository]
Loeffen, W. L. A., de Vries, R. P., Stockhofe, N., van Zoelen-Bos, D., Maas, R., Koch, G., Moormann, R. J. M., Rottier, P. J. M., & de Haan, C. A. M. (2011). Vaccination with a soluble recombinant hemagglutinin trimer protects pigs against a challenge with pandemic (H1N1) 2009 influenza virus. Vaccine, 29(8), 1545-1550. [DOI]
Overige resultaten
Rottier, P. J. M., de Haan, C. A. M., & Bosch, B. J. (2011). Recombinant multimeric influenza proteins. (Patent No. WO 2011/126370).
de Vries, R. P., de Vries, E., Moore, K., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2011). Only two residues are important for the dramatic difference in receptor binding between swine and new pandemic H1 hemagglutinin. Poster session presented at ESWI Conference, Malta.
de Vries, R. P., de Vries, E., Moore, K., Lopez-Cotarelo, P., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2011, Sept 15). Recombinant Soluble Hemagglutinins to study immunogenic and receptor binding properties.
de Vries, E., Tscherne, D. M., Wienholts, M., Cobos-Jiménez, V., Scholte, F., García-Sastre, A., Rottier, P. J. M., & de Haan, C. A. M. (2011). Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an entry pathway. Poster session presented at Keystone Symposium on Patogenesis of Influenza: Virus-Host interactions, Hong Kong.
de Haan, C. A. M., Tscherne, D. M., Wienholts, M., Cobos-Jiménez, V., Scholte, F., García-Sastre, A., & Rottier, P. J. M. (2011). Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an entry pathway. Poster session presented at The Fourth ESWI Influenza Conference, Malta.
de Vries, R. P., de Vries, E., Moore, K., Lopez-Cotarelo, P., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2011, Nov 30). Recombinant Soluble Hemagglutinins to study immunogenic and receptor binding properties.
Monastyrska, I., Ulasli, M., Reggiori, F., Molinari, M., & de Haan, C. A. M. (2011). LC3-I is Abused by Positive-Stranded RNA Viruses for Replication on ER-Derived Vesicles. Poster session presented at Keystone Symposia on Autophagy, Whistler, British Colombia.
de Vries, R. P., de Vries, E., Moore, K., Lopez-Cotarelo, P., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2011, Apr 14). Recombinant Soluble Hemagglutinins to study immunogenic and receptor binding properties.
de Vries, R. P., Smit, C. H., Rigter, A., Cornelissen, L. A. H. M., Eggink, D. W., Sanders, R. W., Hokke, C. H., Rottier, P. J. M., & de Haan, C. A. M. (2011). Glycosylation-dependent immunogenicity of recombinant soluble trimeric hemagglutinin. Poster session presented at Gordons Glycobiology Meeting, Lucca (Barga), Italy.
de Vries, R. P., de Vries, E., Moore, K., Lopez-Cotarelo, P., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2011, Nov 10). Recombinant Soluble Hemagglutinins to study immunogenic and receptor binding properties.
de Vries, R. P., de Vries, E., Moore, K., Lopez-Cotarelo, P., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2011, Oct 4). Recombinant Soluble Hemagglutinins to study immunogenic and receptor binding properties.
2010
Wetenschappelijke publicaties
de Vries, R. P., de Vries, E., Bosch, B. J., de Groot, R. J., Rottier, P. J. M., & de Haan, C. A. M. (2010). The influenza A virus hemagglutinin glycosylation state affects receptor-binding specificity. Virology, 403(1), 17-25. [DOI] [Repository]
Bosch, B. J., Bodewes, R., de Vries, R. P., Kreijtz, J. H. C. M., Bartelink, W., van Amerongen, G., Rimmelzwaan, G. F., de Haan, C. A. M., Osterhaus, A. D. M. E., & Rottier, P. J. M. (2010). Recombinant soluble, multimeric HA and NA exhibit distinctive types of protection against pandemic swine-origin 2009 A(H1N1) influenza virus infection in ferrets. Journal of Virology, 84(19), 10366-10374. [DOI] [Repository]
Raaben, M., Posthuma, C. C., Verheije, M. H., te Lintelo, E. G., Kikkert, M., Drijfhout, J. W., Snijder, E. J., Rottier, P. J. M., & de Haan, C. A. M. (2010). The ubiquitin-proteasome system plays an important role during various stages of the coronavirus infection cycle. Journal of Virology, 84(15), 7869-79. [DOI]
Cornelissen, L. A. H. M., de Vries, R. P., de Boer-Luijtze, E. A., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2010). A single immunization with soluble recombinant trimeric hemagglutinin protects chickens against highly pathogenic avian influenza virus H5N1. PLoS One, 5(5), Article e10645. [DOI] [Repository]
de Haan, C. A. M., Molinari, M., & Reggiori, F. M. (2010). Autophagy-independent LC3 function in vesicular traffic. Autophagy, 6(7), 994-996.
Reggiori, F., Monastyrska, I., Verheije, M. H., Calì, T., Ulasli, M., Bianchi, S., Bernasconi, R., de Haan, C. A. M., & Molinari, M. (2010). Coronaviruses Hijack the LC3-I-positive EDEMosomes, ER-derived vesicles exporting short-lived ERAD regulators, for replication. Cell Host & Microbe, 7(6), 500-508. [DOI]
Verheije, M. H., Hagemeijer, M. C., Ulasli, M., Reggiori, F., Rottier, P. J. M., Masters, P. S., & de Haan, C. A. M. (2010). The coronavirus nucleocapsid protein is dynamically associated with the replication-transcription complexes. Journal of Virology, 84(21), 11575-11579. [DOI]
Raaben, M., Grinwis, G. C. M., Rottier, P. J. M., & de Haan, C. A. M. (2010). The proteasome inhibitor velcade enhances rather than reduces disease in mouse hepatitis coronavirus-infected mice. Journal of Virology, 84(15), 7880-7885. [DOI]
Widjaja, I., de Vries, E., Tscherne, D. M., García-Sastre, A., Rottier, P. J. M., & de Haan, C. A. M. (2010). Inhibition of the ubiquitin-proteasome system affects influenza A virus infection at a postfusion step. Journal of Virology, 84(18), 9625-9631. [DOI]
Hagemeijer, M. C., Verheije, M. H., Ulasli, M., Shaltiël, I. A., de Vries, L. A., Reggiori, F., Rottier, P. J. M., & de Haan, C. A. M. (2010). Dynamics of coronavirus replication-transcription complexes. Journal of Virology, 84(4), 2134-2149. [DOI] [Repository]
Overige resultaten
Bosch, B. J., de Vries, R. P., Cornelissen, L., Bodewes, R., Kreijtz, J., Bartelink, W., Osterhaus, A. D., de Haan, C. A. M., & Rottier, P. J. M. (2010). A novel, effective and versatile vaccine approach against influenza: multimeric recombinant HA and NA glycoproteins. Poster session presented at 4th Vaccine and ISV Annual Global Congress, Vienna, Austria.
de Vries, R. P., Bosch, B. J., Cornelissen, L., Bodewes, R., Kreijtz, J., Bartelink, W., Osterhaus, A. D. M. E., de Haan, C. A. M., & Rottier, P. J. M. (2010). A novel, effective and versatile vaccine approach against influenza: multimeric recombinant HA and NA glycoproteins. Poster session presented at Options for the Control of Influenza VII, Hong Kong, China.
de Haan, C. A. M., Hagemeijer, M. C., Ulasli, M., Neveu, G., Lucas-Hourani, M., Tangy, F., Favre, M., Rottier, P. J. M., Reggiori, F., Vidalain, P. O., & Jacob, Y. (2010). Meta-analysis of coronavirus protein interactomes. Poster session presented at The Ninth International Symposium on positive-strand RNA viruses, Atlanta, USA.
de Haan, C. A. M., Bosch, B. J., & Rottier, P. J. M. (2010). Recombinant multimeric influenza proteins. (Patent No. EP10159552.8).
de Vries, R. P., de Vries, E., Moore, K. S., Rigter, A., Rottier, P. J. M., & de Haan, C. A. M. (2010). The H1 hemagglutinins of swine and new pandemic influenza A viruses differ dramatically in their receptor binding properties: identification of the responsible residues. Poster session presented at Options for control of Influenza VI, Hong Kong, china.
2009
Wetenschappelijke publicaties
Raaben, M., Prins, M., Martens, A. C. M., Rottier, P. J. M., & de Haan, C. A. M. (2009). Non-invasive imaging of mouse hepatitis coronavirus infection reveals determinants of viral replication and spread in vivo. Cellular Microbiology, 11(5), 825-841. [DOI]
Raaben, M., Groot Koerkamp, M. J. A., Rottier, P. J. M., & de Haan, C. A. M. (2009). Type I interferon receptor-independent and -dependent host transcriptional responses to mouse hepatitis coronavirus infection in vivo. BMC Genomics, 10, Article 350. [DOI] [Repository]
Overige resultaten
Hagemeijer, M. C., Verheije, M. H., Ulasli, M., Shaltiël, I. A., de Vries, L. A., Reggiori, F., Rottier, P. J. M., & de Haan, C. A. M. (2009). Dynamics of Coronavirus Replication-Transcription Complexes. Poster session presented at Joint FEBS – EMBO Advanced Lecture Course, Cargèse, Corsica, France.
2008
Wetenschappelijke publicaties
de Haan, C. A. M., Haijema, B. J., Masters, P. S., & Rottier, P. J. M. (2008). Manipulation of the coronavirus genome using targeted recombination with interspecies chimeric coronaviruses. In D. Cavanagh (Ed.), SARS- and Other Coronaviruses: Laboratory Protocols (pp. 229-236). (Methods in Molecular Biology; Vol. 454). Humana Press. [DOI]
Bosch, B. J., Rossen, J. W. A., Bartelink, W., Zuurveen, S. J., de Haan, C. A. M., Duquerroy, S., Boucher, C. A. B., & Rottier, P. J. M. (2008). Coronavirus escape from heptad repeat 2 (HR2)-derived peptide entry inhibition as a result of mutations in the HR1 domain of the spike fusion protein. Journal of Virology, 82(5), 2580-2585. [DOI] [Repository]
Oostra, M., Hagemeijer, M. C., Gent, M., Bekker, C. P. J., te Lintelo, E. G., Rottier, P. J. M., & de Haan, C. A. M. (2008). Topology and Membrane Anchoring of the Coronavirus Replication Complex: Not All Hydrophobic Domains of nsp3 and nsp6 Are Membrane Spanning. Journal of Virology, 82(24), 12392-12405. [DOI]
de Haan, C. A. M., & Reggiori, F. M. (2008). Are nidoviruses hijacking the autophagy machinery? Autophagy, 4(3), 276-279.
Raaben, M., Whitley, P., Bouwmeester, D., Setterquist, R. A., Rottier, P. J. M., & de Haan, C. A. M. (2008). Improved microarray gene expression profiling of virus-infected cells after removal of viral RNA. BMC Genomics, 9, 221. http://www.biomedcentral.com/1471-2164/9/221
de Haan, C. A. M., Haijema, B. J., Schellen, P., Schreur, P. W., te Lintelo, E., Vennema, H., & Rottier, P. J. M. (2008). Cleavage of group 1 coronavirus spike proteins; how furin cleavage is traded off against heparan sulfate binding upon cell culture adaptation. Journal of Virology, 82(12), 6078-6083. [DOI]
Verheije, M. H., Raaben, M., Mari, M., Te Lintelo, E. G., Reggiori, F., van Kuppeveld, F. J. M., Rottier, P. J. M., & de Haan, C. A. M. (2008). Mouse hepatitis coronavirus RNA replication depends on GBF1-mediated ARF1 activation. PLoS Pathogens, 4(6), Article e1000088. [DOI] [Repository]
Overige resultaten
Vogels, M. W., Kaloyanova, D. V., van Balkom, B. W. M., Batenburg, J. J., Helms, J. B., Rottier, P. J. M., & de Haan, C. A. M. (2008). Interactions of intracellular pathogens with the Golgi apparatus.. Poster session presented at The XIth International Symposium on Nidovirus, St. Catherine's College, Oxford, United Kingdom.
2007
Wetenschappelijke publicaties
Eifart, P., Ludwig, K., Bottcher, C., de Haan, C. A. M., Rottier, P. J. M., Korte, T., & Herrmann, A. (2007). The role of endocytosis and low pH in cell entry of the murine hepatitis virus MHV-A59. Journal of Virology, 81(19), 10758-10768.
Raaben, M., Groot Koerkamp, M. J. A., Rottier, P. J. M., & de Haan, C. A. M. (2007). Mouse hepatitis coronavirus replication induces host translational shutoff and mRNA decay, with concomitant formation of stress granules and processing bodies. Cellular Microbiology, 9(9), 2218-2229. [DOI]
Oostra, M., de Haan, C. A. M., & Rottier, P. J. M. (2007). The 29-nucleotide deletion present in human but not in animal SARS coronaviruses disrupts the functional expression of open reading frame 8. Journal of Virology, 81(24), 13876-13888. [DOI]
Oostra, M., te Lintelo, E. G., Deijs, M., Verheije, M. H., Rottier, P. J. M., & de Haan, C. A. M. (2007). Localization and membrane topology of the coronavirus nonstructural protein 4: involvement of the early secretory pathway in replication. Journal of Virology, 81(22), 12323-12336. [DOI]
van der Meer, F. J. U. M., de Haan, C. A. M., Schuurman, N. M., Haijema, B. J., Peumans, W. J., van Damme, E. J., Delputte, P. L., Balzarini, J., & Egberink, H. F. (2007). Antiviral activity of carbohydrate-binding agents against Nidovirales in cell culture. Antiviral Research, 76(1), 21-29. [DOI]
van der Meer, F. J. U. M., de Haan, C. A. M., Schuurman, N. M. P., Haijema, B. J., Verheije, M. H., Bosch, B. J., Balzarini, J., & Egberink, H. F. (2007). The carbohydrate-binding plant lectins and the non-peptidic antibiotic pradimicin A target the glycans of the coronavirus envelope glycoproteins. Journal of Antimicrobial Chemotherapy, 60(4), 741-749. [DOI] [Repository]
Raaben, M., Einerhand, A. W., Taminiau, L. J., van Houdt, M., Bouma, J., Raatgeep, R. H., Buller, H. A., de Haan, C. A. M., & Rossen, J. W. A. (2007). Cyclooxygenase activity is important for efficient replication of mouse hepatitis virus at an early stage of infection. Virology Journal, 4, 55. [Repository]
Overige resultaten
de Haan, C. A. M., Oostra, M., te Lintelo, E. G., Deijs, M., Verheije, M. H., & Rottier, P. J. M. (2007). Membrane topology and subcellular localization of the coronavirus non-structural protein 4.. Poster session presented at RNA Virus Meeting, Washington DC.
Oostra, M., de Haan, C. A. M., & Rottier, P. J. M. (2007). Expression and characterization of the Severe Acute Respiratory Syndrome Coronavirus Orf8-related products which differ between human and animal virus isolates. Poster session presented at RNA Virus Meeting, Washington DC.
Oostra, M., de Haan, C. A. M., & Rottier, P. J. M. (2007). Expression and characterization of the Severe Acute Respiratory Syndrome Coronavirus Orf8-related products which differ between human and animal virus isolates. Poster session presented at FEBS/EMBO advanced lecture course, Cellular and Biology of membranes, Corsica.
2006
Wetenschappelijke publicaties
de Haan, C. A. M., Te Lintelo, E., Li, Z., Raaben, M., Wurdinger, T., Bosch, B. J., & Rottier, P. J. M. (2006). Cooperative involvement of the S1 and S2 subunits of the murine coronavirus spike protein in receptor binding and extended host range. Journal of Virology, 80(22), 10909-10918. [DOI] [Repository]
Verheije, M. H., Würdinger, T., van Beusechem, V. W., de Haan, C. A. M., Gerritsen, W. R., & Rottier, P. J. M. (2006). Redirecting coronavirus to a nonnative receptor through a virus-encoded targeting adapter. Journal of Virology, 80(3), 1250-1260. [DOI]
Würdinger, T., Verheije, M. H., van der Aa, L. M., Bosch, B. J., de Haan, C. A. M., van Beusechem, V. W., Gerritsen, W. R., & Rottier, P. J. M. (2006). Antibody-mediated targeting of viral vectors to the Fc receptor expressed on acute myeloid leukemia cells. Leukemia. Leukemia, 20(12), 2182-2184. [DOI] [Repository]
Schramm, B., de Haan, C. A. M., Young, J., Doglio, L., Schleich, S., Reese, C., Popov, A. V., Steffen, W., Schroer, T., & Locker, J. K. (2006). Vaccinia-virus-induced cellular contractility facilitates the subcellular localization of the viral replication sites. Traffic, 7(10), 1352-1367.
Oostra, M., de Haan, C. A. M., de Groot, R. J., & Rottier, P. J. M. (2006). Glycosylation of the severe acute respiratory syndrome coronavirus triple-spanning membrane proteins 3a and M. Journal of Virology, 80(5), 2326-2336. [DOI] [Repository]
van der Meer, F. J. U. M., Schuurman, N. M. P., Balzarini, J., de Haan, C. A. M., Haijema, B. J., & Egberink, H. F. (Accepted/In press). Carbohydrate binding plant lectins targeting the N-glycosylation of the nidovirus envelope. Abstract from ESVV Meeting, Lisbon, Portugal 2006.
Schepis, A., Schramm, B., de Haan, C. A. M., & Locker, J. K. (2006). Vaccinia virus-induced microtubule-dependent cellular rearrangements. Traffic, 7(3), 308-323. [Repository]
de Haan, C. A. M., & Rottier, P. J. M. (2006). Hosting the severe acute respiratory syndrome coronavirus: specific cell factors required for infection. Cellular Microbiology, 8(8), 1211-1218. [DOI]
2005
Wetenschappelijke publicaties
de Haan, C. A. M., Li, Z., te Lintelo, E., Bosch, B. J., Haijema, B. J., & Rottier, P. J. M. (2005). Murine coronavirus with an extended host range uses heparan sulfate as an entry receptor. Journal of Virology, 79(22), 14451-14456. [DOI] [Repository]
Bosch, B. J., de Haan, C. A. M., Smits, S. L., & Rottier, P. J. M. (2005). Spike protein assembly into the coronavirion: exploring the limits of its sequence requirements. Virology, 334(2), 306-318. [DOI] [Repository]
Würdinger, T., Verheije, M. H., Raaben, M., Bosch, B. J., de Haan, C. A. M., van Beusechem, V. W., Rottier, P. J. M., & Gerritsen, W. R. (2005). Targeting non-human coronaviruses to human cancer cells using a bispecific single-chain antibody. Gene Therapy, 12(18), 1394-1404. [DOI] [Repository]
de Haan, C. A. M., Haijema, B. J., Boss, D., Heuts, F. W., & Rottier, P. J. M. (2005). Coronaviruses as vectors: stability of foreign gene expression. Journal of Virology, 79(20), 12742-12751. [DOI]
Würdinger, T., Verheije, M. H., Broen, K., Bosch, B. J., Haijema, B. J., de Haan, C. A. M., van Beusechem, V. W., Gerritsen, W. R., & Rottier, P. J. M. (2005). Soluble receptor-mediated targeting of mouse hepatitis coronavirus to the human epidermal growth factor receptor. Journal of Virology, 79(24), 15314-15322. [DOI] [Repository]
de Haan, C. A. M., & Rottier, P. J. M. (2005). Molecular interactions in the assembly of coronaviruses. Advances in Virus Research, 64, 165-230. [DOI]
2004
Wetenschappelijke publicaties
de Haan, C. A. M., Stadler, K., Godeke, G.-J., Bosch, B. J., & Rottier, P. J. M. (2004). Cleavage inhibition of the murine coronavirus spike protein by a furin-like enzyme affects cell-cell but not virus-cell fusion. Journal of Virology, 78(11), 6048-54. [DOI] [Repository]
Bosch, B. J., de Haan, C. A. M., & Rottier, P. J. M. (2004). Coronavirus spike glycoprotein, extended at the carboxy terminus with green fluorescent protein, is assembly competent. Journal of Virology, 78(14), 7369-78. [DOI] [Repository]
Overige resultaten
Rottier, P., de Haan, X., Haijema, B. J., & Bosch, B. J. (2004). Coronavirus-like particles comprising functionally deleted genomes.
Verheije, M. H., Würdinger, T., Raaben, M., Bosch, B. J., van Beusechem, V. W., de Haan, C. A. M., Rottier, P. J. M., & Gerritsen, W. R. (2004). Non-human coronaviruses as potential tool for cancer therapy: selective targeting to and effective eradication of human tumor cells in vitro. Poster session presented at 7th international symposium on positive strand RNA viruses, San Francisco (USA).
2003
Wetenschappelijke publicaties
Bosch, B. J., van der Zee, R., de Haan, C. A. M., & Rottier, P. J. M. (2003). The coronavirus spike protein is a class I virus fusion protein: structural and functional characterization of the fusion core complex. Journal of Virology, 77(16), 8801-11. [DOI] [Repository]
de Haan, C. A. M., van Genne, L., Stoop, J. N., Volders, H., & Rottier, P. J. M. (2003). Coronaviruses as vectors: position dependence of foreign gene expression. Journal of Virology, 77, 11312-11323. [DOI]
de Haan, C. A. M., de Wit, M., Kuo, L., Montalto-Morrison, C., Haagmans, B. L., Weiss, S. R., Masters, P. S., & Rottier, P. J. M. (2003). The glycosylation status of the murine hepatitis coronavirus M protein affects the interferogenic capacity of the virus in vitro and its ability to replicate in the liver but not the brain. Virology, 312, 395-406. [DOI]
2002
Wetenschappelijke publicaties
de Haan, C. A. M., Volders, H., Koetzner, C. A., Masters, P. S., & Rottier, P. J. M. (2002). Coronaviruses maintain viability despite dramatic rearrangements of the strictly conserved genome organization. Journal of Virology, 76, 12491-12502. [DOI]
de Haan, C. A. M., de Wit, M., Kuo, L., Montalto, C., Masters, P. S., Weiss, S. R., & Rottier, P. J. M. (2002). O-glycosylation of the mouse hepatitis coronavirus membrane protein. Virus Research, 82, 77-81. [DOI]
de Haan, C. A. M., Masters, P. S., Shen, X., Weiss, S., & Rottier, P. J. M. (2002). The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host. Virology, 296, 177-189. [DOI]
2000
Wetenschappelijke publicaties
de Vries, A. A., Glaser, A. L., Raamsman, M. J., de Haan, C. A., Sarnataro, S., Godeke, G. J., & Rottier, P. J. (2000). Genetic manipulation of equine arteritis virus using full-length cDNA clones: separation of overlapping genes and expression of a foreign epitope. Virology, 270(1), 84-97. [DOI]
Godeke, G. J., de Haan, C. A., Rossen, J. W., Vennema, H., & Rottier, P. J. (2000). Assembly of spikes into coronavirus particles is mediated by the carboxy-terminal domain of the spike protein. Journal of Virology, 74(3), 1566-1571. [DOI]
de Haan, C. A. M. (2000). The Corona virus membrane protein: role in assembly. [Doctoral thesis 1 (Research UU / Graduation UU), Utrecht University].
de Haan, C. A. M., Vennema, H., & Rottier, P. J. M. (2000). Assembly of the coronavirus envelope: homotypic interactions between the M proteins. Journal of Virology, 74, 4967-4978. [DOI]
1999
Wetenschappelijke publicaties
de Haan, C. A., Smeets, M., Vernooij, F., Vennema, H., & Rottier, P. J. (1999). Mapping of the coronavirus membrane protein domains involved in interaction with the spike protein. Journal of Virology, 73(9), 7441-52.
1998
Wetenschappelijke publicaties
de Haan, C. A., Vennema, H., & Rottier, P. J. (1998). Coronavirus envelope assembly is sensitive to changes in the terminal regions of the viral M protein. In Coronaviruses and Arteriviruses (pp. 367-75). (Advances in Experimental Medicine and Biology; Vol. 440). Springer. [DOI]
de Haan, C. A., Kuo, L., Masters, P. S., Vennema, H., & Rottier, P. J. (1998). Coronavirus particle assembly: primary structure requirements of the membrane protein. Journal of Virology, 72(8), 6838-50.
de Haan, C. A., Roestenberg, P., de Wit, M., de Vries, A. A., Nilsson, T., Vennema, H., & Rottier, P. J. (1998). Structural requirements for O-glycosylation of the mouse hepatitis virus membrane protein. Journal of Biological Chemistry, 273(45), 29905-14. [DOI] [Repository]