Publications
2024
Scholarly publications
Chen, Y., Steeneveld, W., Frankena, K., Leemans, I., Aardema, H., Vos, P. L. A. M., Nielen, M., & Hostens, M. (2024). Association between days post conception and lactation persistency in dairy cattle. Journal of Dairy Science. Advance online publication. https://doi.org/10.3168/jds.2023-24282
Chin, W., Steeneveld, W., Nielen, M., Christensen, J., Klaas, I. C., & Lam, T. J. G. M. (2024). The association between time-series milk β-hydroxybutyrate dynamics and early reproductive performance of dairy cows. Journal of Dairy Science. Advance online publication. https://doi.org/10.3168/jds.2023-24184
Meletis, E., Conrady, B., Hopp, P., Lurier, T., Frössling, J., Rosendal, T., Faverjon, C., Carmo, L. P., Hodnik, J. J., Ózsvári, L., Kostoulas, P., van Schaik, G., Comin, A., Nielen, M., Knific, T., Schulz, J., Šerić-Haračić, S., Fourichon, C., Santman-Berends, I., & Madouasse, A. (2024). Review state-of-the-art of output-based methodological approaches for substantiating freedom from infection. Frontiers in Veterinary Science, 11, Article 1337661. https://doi.org/10.3389/fvets.2024.1337661
https://dspace.library.uu.nl/bitstream/handle/1874/437762/fvets-11-1337661.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/437762/fvets-11-1337661.pdf?sequence=1
Janssen, E. R., Nielen, M., Spithoven, J. J. G., van Werven, T., & Wouters, I. M. (2024). Observational study on occupational exposure of dairy farmers to formaldehyde. Occupational and Environmental Medicine, 81(1), 48-54. Article oemed-2022-108753. https://doi.org/10.1136/oemed-2022-108753
2023
Scholarly publications
Chen, Y., Steeneveld, W., Nielen, M., & Hostens, M. (2023). Prediction of persistency for day 305 of lactation at the moment of the insemination decision. Frontiers in Veterinary Science, 10, Article 1264048. https://doi.org/10.3389/fvets.2023.1264048
Kulkarni, P. S., Mourits, M. C. M., Slob, J., Veldhuis, A. M. B., Nielen, M., Hogeveen, H., Schaik, G. V., & Steeneveld, W. (2023). Dutch dairy farmers' perspectives on culling reasons and strategies. Preventive Veterinary Medicine, 218, 1-6. Article 105997. https://doi.org/10.1016/j.prevetmed.2023.105997
Ni, H., Koop, G., Klugkist, I., & Nielen, M. (2023). Evaluation of Bayesian Hui-Walter and logistic regression latent class models to estimate diagnostic test characteristics with simulated data. Preventive Veterinary Medicine, 217, Article 105972. https://doi.org/10.1016/j.prevetmed.2023.105972
Van Schaik, G., Madouasse, A., van Roon, A. M., More, S. J., Graham, D. A., Frossling, J., Gethmann, J. M., Fourichon, C., Mercat, M., Agren, E., Sauter-Louis, C., Gunn, G. J., Eze, J., Humphry, R., Henry, M. K., Guelbenzu-Gonzalo, M., Nielen, M., & Santman-Berends, I. M. G. (2023). A framework for assessing confidence in freedom from infection in animal disease control programmes. Revue scientifique et technique (International Office of Epizootics), 42, 210-217. https://doi.org/10.20506/rst.42.3364
Schaik, G. V., Hostens, M., Faverjon, C., Jensen, D. B., Kristensen, A. R., Ezanno, P., Frössling, J., Dórea, F., Jensen, B.-B., Carmo, L. P., Steeneveld, W., Rushton, J., Gilbert, W., Bearth, A., Siegrist, M., Kaler, J., Ripperger, J., Siehler, J., Wit, S. D., ... Nielen, M. (2023). The DECIDE project: from surveillance data to decision-support for farmers and veterinarians. Open Research Europe, 3(82), 1-8. https://doi.org/10.12688/openreseurope.15988.1
Kulkarni, P. S., Mourits, M., Nielen, M., & Steeneveld, W. (2023). Associations between dairy farm performance indicators and culling rates under policy-driven herd size constraints. Frontiers in Veterinary Science, 10, Article 1062891. https://doi.org/10.3389/fvets.2023.1062891
Elte, Y., Acton, K., Martin, J., Nielen, M., van Weeren, R., & Wolframm, I. (2023). Engage and enjoy-investigating predictors of employee engagement and work satisfaction in equine veterinary professionals. Frontiers in Veterinary Science, 10, 1-11. Article 1036388. https://doi.org/10.3389/fvets.2023.1036388
Vanhoudt, A., Jacobs, C., Caron, M., Barkema, H. W., Nielen, M., van Werven, T., & Orsel, K. (2023). Broad-spectrum infrared thermography for detection of M2 digital dermatitis lesions on hind feet of standing dairy cattle. PLoS One, 18(1), Article e0280098. https://doi.org/10.1371/journal.pone.0280098
2022
Scholarly publications
Luo, T., Steeneveld, W., Nielen, M., Zanini, L., & Zecconi, A. (2022). Linear Mixed-Effects Model to Quantify the Association between Somatic Cell Count and Milk Production in Italian Dairy Herds. Animals, 13(1), Article 80. https://doi.org/10.3390/ani13010080
Hut, P. R., Scheurwater, J., Nielen, M., van den Broek, J., & Hostens, M. M. (2022). Heat stress in a temperate climate leads to adapted sensor-based behavioral patterns of dairy cows. Journal of Dairy Science, 105(8), 6909-6922. https://doi.org/10.3168/jds.2021-21756
Chen, Y., Hostens, M., Nielen, M., Ehrlich, J., & Steeneveld, W. (2022). Herd level economic comparison between the shape of the lactation curve and 305 d milk production. Frontiers in Veterinary Science, 9, 1-11. Article 997962. https://doi.org/10.3389/fvets.2022.997962
van Roon, A. M., Madouasse, A., Toft, N., Santman-Berends, I. M. G. A., Gethmann, J., Eze, J., Humphry, R. W., Graham, D., Guelbenzu-Gonzalo, M., Nielen, M., More, S. J., Mercat, M., Fourichon, C., Sauter-Louis, C., Frössling, J., Ågren, E., Gunn, G. J., Henry, M. K., & van Schaik, G. (2022). Output-based assessment of herd-level freedom from infection in endemic situations: Application of a Bayesian Hidden Markov model. Preventive Veterinary Medicine, 204, 1-9. Article 105662. https://doi.org/10.1016/j.prevetmed.2022.105662
Hut, P. R., Kuiper, S. E. M., Nielen, M., Hulsen, J. H. J. L., Stassen, E. N., & Hostens, M. M. (2022). Sensor based time budgets in commercial Dutch dairy herds vary over lactation cycles and within 24 hours. PLoS One, 17(2), 1-19. Article e0264392. https://doi.org/10.1371/journal.pone.0264392
Robbers, L., van de Mheen, R., Benedictus, L., Jorritsma, R., Nielen, M., Bijkerk, H. J. C., van der Grein, S. G., Ravesloot, L., & Koets, A. P. (2022). Evidence for transfer of maternal antigen specific cellular immunity against Mycobacterium avium ssp. paratuberculosis via colostrum in a goat twin model. Veterinary Immunology and Immunopathology, 246, 1-11. Article 110402. https://doi.org/10.1016/j.vetimm.2022.110402
Mercat, M., Roon, A. M. V., Santman-Berends, I., Schaik, G. V., Nielen, M., More, S. J., Guelbenzu-Gonzalo, M., Fourichon, C., & Madouasse, A. (2022). Capacity of a Bayesian model to detect infected herds using disease dynamics and risk factor information from surveillance programmes: A simulation study. Preventive Veterinary Medicine, 200, 1-13. Article 105582. https://doi.org/10.1016/j.prevetmed.2022.105582
Vanhoudt, A., Hesseling, J., Nielen, M., Wilmink, J., Jorritsma, R., & van Werven, T. (2022). M-score and wound healing assessment of 2 nonantibiotic topical gel treatments of active digital dermatitis lesions in dairy cattle. Journal of Dairy Science, 105(1), 695-709. https://doi.org/10.3168/jds.2021-20613
2021
Scholarly publications
Scheurwater, J., Jorritsma, R., Nielen, M., Heesterbeek, H., van den Broek, J., & Aardema, H. (2021). The effects of cow introductions on milk production and behaviour of the herd measured with sensors. Journal of Dairy Research, 88(4), 374-380. https://doi.org/10.1017/S0022029921000856
Angkavanich, T., Vernooij, H., Sirimalaisuwan, A., Charernpan, P., Nielen, M., & Rutten, V. (2021). Prevalence and Demographic Risk Factors of Mycobacterium tuberculosis Infections in Captive Asian Elephants (Elephas maximus) Based on Serological Assays. Frontiers in Veterinary Science, 8, 1-9. Article 713663. https://doi.org/10.3389/fvets.2021.713663
Robbers, L., Jorritsma, R., Nielen, M., & Koets, A. (2021). A Scoping Review of On-Farm Colostrum Management Practices for Optimal Transfer of Immunity in Dairy Calves. Frontiers in Veterinary Science, 8, 1-16. Article 668639. https://doi.org/10.3389/fvets.2021.668639
Scheurwater, J., Hostens, M., Nielen, M., Heesterbeek, H., Schot, A., van Hoeij, R., & Aardema, H. (2021). Pressure measurement in the reticulum to detect different behaviors of healthy cows. PLoS One, 16(7), 1-13. Article e0254410. https://doi.org/10.1371/journal.pone.0254410
Tijssen, M., Serra Braganca, F., Ask, K., Rhodin, M., Andersen, P., Telezhenko, E., Bergsten, C., Nielen, M., & Hernlund, E. (2021). Kinematic gait characteristics of straight line walk in clinically sound dairy cows. PLoS One, 16(7), 1-20. Article e0253479. https://doi.org/10.1371/journal.pone.0253479
Elte, Y., Wolframm, I., Nielen, M., & van Weeren, R. (2021). Client satisfaction in equine veterinary practice: A structured review and qualitative synthesis. Veterinary Record, 189(10), 1-10. Article e640. https://doi.org/10.1002/vetr.640
Aldewereld, C. M., Monninkhof, E. M., Kroese, F. M., de Ridder, D. T. D., Nielen, M., & Corbee, R. J. (2021). Discussing overweight in dogs during a regular consultation in general practice in the Netherlands. Journal of Animal Physiology and Animal Nutrition, 105(S1), 56-64. https://doi.org/10.1111/jpn.13558
Kulkarni, P., Mourits, M., Nielen, M., van den Broek, J., & Steeneveld, W. (2021). Survival analysis of dairy cows in the Netherlands under altering agricultural policy. Preventive Veterinary Medicine, 193, Article 105398. https://doi.org/10.1016/j.prevetmed.2021.105398
van Roon, A. M., Rapaliute, E., Koleci, X., Muñoz, V., Mercat, M., Faverjon, C., Santman-Berends, I. M. G. A., Nielen, M., More, S. J., Graham, D., Guelbenzu-Gonzalo, M., Madouasse, A., Fourichon, C., & van Schaik, G. (2021). Key Learnings During the Development of a Generic Data Collection Tool to Support Assessment of Freedom of Infection in Cattle Herds. Frontiers in Veterinary Science, 8, Article 656336. https://doi.org/10.3389/fvets.2021.656336
Niese, J. R., Mepham, T., Nielen, M., Monninkhof, E. M., Kroese, F. M., de Ridder, D. T. D., & Corbee, R. J. (2021). Evaluating the Potential Benefit of a Combined Weight Loss Program in Dogs and Their Owners. Frontiers in Veterinary Science, 8, Article 653920. https://doi.org/10.3389/fvets.2021.653920
Robbers, L., Bijkerk, H., Koets, A. P., Benedictus, L., Nielen, M., & Jorritsma, R. (2021). Survey on Colostrum Management by Dairy Farmers in the Netherlands. Frontiers in Veterinary Science, 8, 1-10. Article 656391. https://doi.org/10.3389/fvets.2021.656391
Hut, P. R., Hostens, M. M., Beijaard, M. J., van Eerdenburg, F. J. C. M., Hulsen, J. H. J. L., Hooijer, G. A., Stassen, E. N., & Nielen, M. (2021). Associations between body condition score, locomotion score, and sensor-based time budgets of dairy cattle during the dry period and early lactation. Journal of Dairy Science, 104(4), 4746-4763. https://doi.org/10.3168/jds.2020-19200
Strous, E., Vanhoudt, A., Smolenaars, A., van Schaik, G., Schouten, M., de Pater, H., Roelofs, B., & Nielen, M. (2021). Observational study on variation of longitudinal platelet counts in calves over the first 14 days of life and reference intervals from cross-sectional platelet and leukocyte counts in dairy calves up to two months of age. Animals, 11(2), 1-13. Article 347. https://doi.org/10.3390/ani11020347
van den Crommenacker-Konings, L. W. J. H., van Dam, P., Everts, R., Shittu, A., Nielen, M., Lam, T. J. G. M., & Koop, G. (2021). Dynamics of intramammary infections in suckler ewes during early lactation. Journal of Dairy Science, 104(5), 5979-5987. https://doi.org/10.3168/jds.2020-19865
https://dspace.library.uu.nl/bitstream/handle/1874/411711/1_s2.0_S0022030221002332_main.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/411711/1_s2.0_S0022030221002332_main.pdf?sequence=1
Ni, H., Klugkist, I., van der Drift, S., Jorritsma, R., Hooijer, G., & Nielen, M. (2021). Expert opinion as priors for random effects in Bayesian prediction models: Subclinical ketosis in dairy cows as an example. PLoS One, 16(1), Article e0244752. https://doi.org/10.1371/journal.pone.0244752
Vanhoudt, A., Orsel, K., Nielen, M., & van Werven, T. (2021). An observational study on the management of digital dermatitis through a repeated risk assessment on 19 Dutch dairy herds. Journal of Dairy Science, 104(1), 947-956. https://doi.org/10.3168/jds.2020-18730
Veraa, S., Scheffer, C. J. W., Smeets, D. H. M., de Bruin, R. B., Hoogendoorn, A. C., Vernooij, J. C. M., Nielen, M., & Back, W. (2021). Cervical disc width index is a reliable parameter and consistent in young growing Dutch Warmblood horses. Veterinary Radiology and Ultrasound, 62(1), 11-19. https://doi.org/10.1111/vru.12913
2020
Scholarly publications
Madouasse, A., Mercat, M., Roon, A. V., Graham, D., Guelbenzu, M., Berends, I. S., Schaik, G. V., Nielen, M., Frössling, J., Ågren, E., Humphry, R., Eze, J., Gunn, G., Henry, M., Gethmann, J., More, S. J., & Fourichon, C. (2020, Jul 12). A modelling framework for the prediction of the herd-level probability of infection from longitudinal data. bioRxiv. https://doi.org/10.1101/2020.07.10.197426
van Roon, A. M., Mercat, M., van Schaik, G., Nielen, M., Graham, D. A., More, S. J., Guelbenzu-Gonzalo, M., Fourichon, C., Madouasse, A., & Santman-Berends, I. M. G. A. (2020). Quantification of risk factors for bovine viral diarrhea virus in cattle herds: A systematic search and meta-analysis of observational studies. Journal of Dairy Science, 103(10), 9446-9463. https://doi.org/10.3168/jds.2020-18193
Tijssen, M., Hernlund, E., Rhodin, M., Bosch, S., Voskamp, J. P., Nielen, M., & Serra Braganςa, F. M. (2020). Correction: Automatic detection of break-over phase onset in horses using hoof-mounted inertial measurement unit sensors. PLoS One, 15(7), Article e0236181. https://doi.org/10.1371/journal.pone.0236181
Tijssen, M., Hernlund, E., Rhodin, M., Bosch, S., Voskamp, J. P., Nielen, M., & Serra Braganςa, F. M. (2020). Erratum: Correction: Automatic hoof-on and -off detection in horses using hoof-mounted inertial measurement unit sensors. PLoS One, 15(7), Article e0236138. https://doi.org/10.1371/journal.pone.0236138
Tijssen, M., Hernlund, E. L., Rhodin, M., Bosch, S., voskamp, J. P., Nielen, M., & Serra Braganca, F. M. (2020). Automatic hoof-on and -off detection in horses using hoof-mounted inertial measurement unit sensors. PLoS One, 15(6), Article e0236138. https://doi.org/10.1371/journal.pone.0233266
van Roon, A. M., Santman-Berends, I. M. G. A., Graham, D., More, S. J., Nielen, M., van Duijn, L., Mercat, M., Fourichon, C., Madouasse, A., Gethmann, J., Sauter-Louis, C., Frössling, J., Lindberg, A., Correia-Gomes, C., Gunn, G. J., & van Schaik, G. (2020). A description and qualitative comparison of the elements of heterogeneous bovine viral diarrhea control programs that influence confidence of freedom. Journal of Dairy Science, 103(5), 4654-4671. https://doi.org/10.3168/jds.2019-16915
van der Maas, J. C., Corbee, R. J., Kroese, F. M., de Ridder, D. T. D., Vos, R. C., Nielen, M., & Monninkhof, E. (2020). Discussing overweight in children during a regular consultation in general practice: a qualitative study. BMC Family Practice, 21(1), Article 18. https://doi.org/10.1186/s12875-020-1088-3
2019
Scholarly publications
Angkawanish, T., Nielen, M., Vernooij, J. C. M., Brown, J., van Kooten, P. J. S., van den Doel, P. B., Schaftenaar, W., Na Lampang, K., & Rutten, V. P. M. G. (2019). EEHV in Asian elephants: Evidence of high seroprevalence in Thailand. Poster session presented at Veterinary Science Day , Bunnik, Netherlands.
Veraa, S., Bergmann, W., Wijnberg, I. D., Back, W., Vernooij, H., Nielen, M., & den Belt, AJ. M. (2019). Equine cervical intervertebral disc degeneration is associated with location and MRI features. Veterinary Radiology and Ultrasound, 2019. https://doi.org/10.1111/vru.12794
Keijser, S. F. A., Vernooij, J. C. M., van Garderen, E., van Rooijen, P., Fieten, H., van Steenbeek, F. G., Hesselink, J. W., & Nielen, M. (2019). Quantification of the health-status of the Dutch Labrador retriever population. Preventive Veterinary Medicine, 171, Article 104764. https://doi.org/10.1016/j.prevetmed.2019.104764
https://dspace.library.uu.nl/bitstream/handle/1874/384847/Quantification.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/384847/Quantification.pdf?sequence=1
Jorritsma, R., van Geijlswijk, I. M., & Nielen, M. (2019). Corrigendum to "Randomized prospective trials to study effects of reduced antibiotic usage in abdominal surgery in cows" (J. Dairy Sci. 101:8217-8223). Journal of Dairy Science, 102(7), 6700. https://doi.org/10.3168/jds.2019-102-7-6700
Veraa, S., de Graaf, K., Wijnberg, I. D., Back, W., Vernooij, H., Nielen, M., & van den Belt, A.-J. M. (2019). Caudal cervical vertebral morphological variation is not associated with clinical signs in Warmblood horses. Equine Veterinary Journal, 219-224. https://doi.org/10.1111/evj.13140
van den Borne, B. H. P., van Schaik, G., Lam, T. J. G. M., Nielen, M., & Frankena, K. (2019). Intramammary antimicrobial treatment of subclinical mastitis and cow performance later in lactation. Journal of Dairy Science, 102(5), 4441-4451. https://doi.org/10.3168/jds.2019-16254
van Roon, A. M., Santman-Berends, I. M. G. A., Graham, D., More, S. J., Nielen, M., Madouasse, A., Mercat, M., Fourichon, C., Gethmann, J., Frössling, J., Lindberg, A., Correia-Gomes, C., Gunn, G. J., Sauter-Louis, C., Henry, M. K., van Duijn, L., & van Schaik, G. (2019). STOC Free: An Innovative Framework to Compare Probability of Freedom From Infection in Heterogeneous Control Programmes. Frontiers in Veterinary Science, 6, Article 133. https://doi.org/10.3389/fvets.2019.00133
Hut, P. R., Mulder, A., van den Broek, J., L. Hulsen, J. H. J., Hooijer, G. A., Stassen, E. N., van Eerdenburg, F. J. C. M., & Nielen, M. (2019). Sensor based eating time variables of dairy cows in the transition period related to the time to first service. Preventive Veterinary Medicine, 169, Article 104694. https://doi.org/10.1016/j.prevetmed.2019.104694
Vanhoudt, A., Yang, D. A., Armstrong, T., Huxley, J. N., Laven, R. A., Manning, A. D., Newsome, R. F., Nielen, M., van Werven, T., & Bell, N. J. (2019). Interobserver agreement of digital dermatitis M-scores for photographs of the hind feet of standing dairy cattle. Journal of Dairy Science, 102(6), 5466-5474. https://doi.org/10.3168/jds.2018-15644
Angkawanish, T., Nielen, M., Vernooij, H., Brown, J. L., van Kooten, P. J. S., van den Doel, P. B., Schaftenaar, W., Na Lampang, K., & Rutten, V. P. M. G. (2019). Evidence of high EEHV antibody seroprevalence and spatial variation among captive Asian elephants (Elephas maximus) in Thailand. Virology Journal, 16(1), Article 33. https://doi.org/10.1186/s12985-019-1142-8
Hordijk, J., Fischer, E. A. J., van Werven, T., Sietsma, S., Van Gompel, L., Timmerman, A. J., Spaninks, M. P., Heederik, D. J. J., Nielen, M., Wagenaar, J. A., & Stegeman, A. (2019). Dynamics of faecal shedding of ESBL- or AmpC-producing Escherichia coli on dairy farms. Journal of Antimicrobial Chemotherapy, 74(6), 1531-1538. https://doi.org/10.1093/jac/dkz035
Gussmann, M., Steeneveld, W., Kirkeby, C., Hogeveen, H., Nielen, M., Farre, M., & Halasa, T. (2019). Economic and epidemiological impact of different intervention strategies for clinical contagious mastitis. Journal of Dairy Science, 102(2), 1483-1493. https://doi.org/10.3168/jds.2018-14939
De Rooij, M. M. T., Van Leuken, J. P. G., Swart, A., Kretzschmar, M. E. E., Nielen, M., De Koeijer, A. A., Janse, I., Wouters, I. M., & Heederik, D. J. J. (2019). A systematic knowledge synthesis on the spatial dimensions of Q fever epidemics. Zoonoses and Public Health, 66(1), 14-25. https://doi.org/10.1111/zph.12534
2018
Scholarly publications
Jorritsma, R., van Geijlswijk, I. M., & Nielen, M. (2018). Two clinical trials: surgery in cows. Abstract from World Buiatrics Congress 2018 Sapporo Japan, Sapporo, Japan.
Keijser, S. F. A., Fieten, H., Vos-Loohuis, M., Piek, C. J., Anderson, H., Donner, J., Scholten, I., Nielen, M., Hesselink, J. W., & van Steenbeek, F. G. (2018). DNA panel screening as a potential tool to monitor health and inbreeding in a small, closed dog population. Canine genetics and epidemiology, 5(12), Article 12. https://doi.org/10.1186/s40575-018-0068-6
Jorritsma, R., van Geijlswijk, I. M., & Nielen, M. (2018). Randomized prospective trials to study effects of reduced antibiotic usage in abdominal surgery in cows. Journal of Dairy Science, 101(9), 8217-8223. https://doi.org/10.3168/jds.2017-14158
van Werven, T., Wilmink, J. M., Sietsma, S., van den Broek, J., & Nielen, M. (2018). A randomized clinical trial of topical treatments for mild and severe udder cleft dermatitis in Dutch dairy cows. Journal of Dairy Science, 101(9), 8259-8268. https://doi.org/10.3168/jds.2017-13778
Van De Reep, L., Nielen, M., Verstappen, K. M. H. W., Broens, E. M., Van Den Broek, J., & Velkers, F. C. (2018). Response to a Salmonella Enteritidis challenge in old laying hens with different vaccination histories. Poultry Science, 97(8), 2733-2739. https://doi.org/10.3382/ps/pey134
Keijser, S. F. A., Vernooij, J. C. M., Rothuizen, J., Fieten, H., Nielen, M., Hesselink, J. W., & van Steenbeek, F. G. (2018). PETscan: measuring incidence of disease phenotypes to prioritize genetic studies in companion animals. Animal Genetics, 49(5), 492-495. https://doi.org/10.1111/age.12707
Ni, H., Groenwold, R. H. H., Nielen, M., & Klugkist, I. (2018). Prediction models for clustered data with informative priors for the random effects: a simulation study. BMC Medical Research Methodology, 18(1), Article 83. https://doi.org/10.1186/s12874-018-0543-5
Ghebremariam, M. K., Michel, A. L., Vernooij, J. C. M., Nielen, M., & Rutten, V. P. M. G. (2018). Prevalence of bovine tuberculosis in cattle, goats, and camels of traditional livestock raising communities in Eritrea. BMC Veterinary Research, 14(1), Article 73. https://doi.org/10.1186/s12917-018-1397-0
Vanhoudt, A., van Hees-Huijps, K., Knegsel, A. T. M., Sampimon, O. C., Vernooij, J. C. M., Nielen, M., & van Werven, T. (2018). Effects of reduced intramammary antimicrobial use during the dry period on udder health in Dutch dairy herds. Journal of Dairy Science, 101(4), 3248-3260. https://doi.org/10.3168/jds.2017-13555
Ghebremariam, M. K., Michel, A. L., Nielen, M., Vernooij, J. C. M., & Rutten, V. P. M. G. (2018). Farm-level risk factors associated with bovine tuberculosis in the dairy sector in Eritrea. Transboundary and Emerging Diseases, 65(1), 105-113. https://doi.org/10.1111/tbed.12622
2017
Scholarly publications
Jorritsma, R., Nielen, M., & Dotinga, A. (2017). A Randomised Non-inferiority Trial on the Effect of an Antibiotic or Non-antibiotic Topical Treatment Protocol for Digital Dermatitis in Dairy Cattle: a knowledge summary. Veterinary Evidence, 2(4). https://doi.org/10.18849/ve.v2i4.111
Sauter-Louis, C., Jones, B. A., Henning, J., Stoll, A., Nielen, M., Van Schaik, G., Smolenaars, A., Schouten, M., den Uijl, I., Fourichon, C., Guatteo, R., Madouasse, A., Nusinovici, S., Deprez, P., De Vliegher, S., Laureyns, J., Booth, R., Cardwell, J. M., & Pfeiffer, D. U. (2017). Herd-level animal management factors associated with the occurrence of bovine neonatal pancytopenia in calves in a multi-country study. PLoS One, 12(7), Article e0179878. https://doi.org/10.1371/journal.pone.0179878
Rutten, C. J., Kamphuis, C., Hogeveen, H., Huijps, K., Nielen, M., & Steeneveld, W. (2017). Sensor data on cow activity, rumination, and ear temperature improve prediction of the start of calving in dairy cows. Computers and Electronics in Agriculture, 132, 108-118. https://doi.org/10.1016/j.compag.2016.11.009
Keijser, S. F. A., Meijndert, L. E., Fieten, H., Carrière, B. J., van Steenbeek, F. G., Leegwater, P. A. J., Rothuizen, J., & Nielen, M. (2017). Disease burden in four populations of dog and cat breeds compared to mixed-breed dogs and European shorthair cats. Preventive Veterinary Medicine, 140, 38-44. https://doi.org/10.1016/j.prevetmed.2017.02.016
https://dspace.library.uu.nl/bitstream/handle/1874/360829/1_s2.0_S0167587717301708_main.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/360829/1_s2.0_S0167587717301708_main.pdf?sequence=1
2016
Scholarly publications
Corbee, R. J., Nielen, M., & Favier, R. P. (2016). Evidence-Based Case Reports: well reasoned decisions. Tijdschrift voor Diergeneeskunde, 141(1), 28-29.
Butler, C. M., van Oldruitenborgh-Oosterbaan, M. M. S., Werners, A. H., Stout, T. A. E., Nielen, M., Jongejan, F., van der kolk, J. H., & Houwers, D. J. (2016). Borrelia burgdorferi and Anaplasma phagocytophilum in ticks and their equine hosts: A prospective clinical and diagnostic study of 47 horses following removal of a feeding tick. Pferdeheilkunde, 32(4), 335-345. https://doi.org/10.21836/PEM20160406
Bouma, A., Nielen, M., van Soest, E., Sietsma, S., van den Broek, J., Dijkstra, T., & van Werven, T. (2016). Longitudinal study of udder cleft dermatitis in 5 Dutch dairy cattle herds. Journal of Dairy Science, 99(6), 4487-4495. https://doi.org/10.3168/jds.2015-9774
https://dspace.library.uu.nl/bitstream/handle/1874/345963/11_main.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/345963/11_main.pdf?sequence=1
Rutten, C. J., Steeneveld, W., Vernooij, J. C. M., Huijps, K., Nielen, M., & Hogeveen, H. (2016). A prognostic model to predict the success of artificial insemination in dairy cows based on readily available data. Journal of Dairy Science, 99(8), 6764-6779. https://doi.org/10.3168/jds.2016-10935
Ghebremariam, M. K., Rutten, V. P. M. G., Vernooij, J. C. M., Uqbazghi, K., Tesfaalem, T., Butsuamlak, T., Idris, A. M., Nielen, M., & Michel, A. L. (2016). Prevalence and risk factors of bovine tuberculosis in dairy cattle in Eritrea. BMC Veterinary Research, 12, Article 80. https://doi.org/10.1186/s12917-016-0705-9
Maurice, H., Thulke, H.-H., Schmid, J. S., Stegeman, A., & Nielen, M. (2016). The impact of compartmentalised housing on direct encephalomyocarditis virus (EMCV) transmission among pigs; insight from a model. Preventive Veterinary Medicine, 127, 105-12. https://doi.org/10.1016/j.prevetmed.2016.03.006
Schmidt, A. F., Klungel, O. H., Nielen, M., de Boer, A., Groenwold, R. H. H., & Hoes, A. W. (2016). Tailoring treatments using treatment effect modification. Pharmacoepidemiology and Drug Safety, 25(4), 355-362. https://doi.org/10.1002/pds.3965
Deng, H., Dam-Deisz, C., Luttikholt, S., Maas, M., Nielen, M., Swart, A., Vellema, P., van der Giessen, J., & Opsteegh, M. (2016). Risk factors related to Toxoplasma gondii seroprevalence in indoor-housed Dutch dairy goats. Preventive Veterinary Medicine, 124, 45-51. https://doi.org/10.1016/j.prevetmed.2015.12.014
https://dspace.library.uu.nl/bitstream/handle/1874/345428/Risk.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/345428/Risk.pdf?sequence=1
Schmidt, A. F., Groenwold, R. H. H., Amsellem, P., Bacon, N., Klungel, O. H., Hoes, A. W., de Boer, A., Kow, K., Maritato, K., Kirpensteijn, J., & Nielen, M. (2016). Which dogs with appendicular osteosarcoma benefit most from chemotherapy after surgery? Results from an individual patient data meta-analysis. Preventive Veterinary Medicine, 125, 116–125. https://doi.org/10.1016/j.prevetmed.2015.10.016
Schmidt, A. F., Nielen, M., Withrow, S. J., Selmic, L. E., Burton, J. H., Klungel, O. H., Groenwold, R. H. H., & Kirpensteijn, J. (2016). Chemotherapy effectiveness and mortality prediction in surgically treated osteosarcoma dogs: A validation study. Preventive Veterinary Medicine, 125, 126-134. https://doi.org/10.1016/j.prevetmed.2016.01.004
Holm, D. E., Nielen, M., Jorritsma, R., Irons, P. C., & Thompson, P. N. (2016). Ultrasonographic reproductive tract measures and pelvis measures as predictors of pregnancy failure and anestrus in restricted bred beef heifers. Theriogenology, 85(3), 495–501. https://doi.org/10.1016/j.theriogenology.2015.09.031
Other output
Ni, H., Groenwold, R., Nielen, M., & Klugkist, I. G. (2016). ISCB2016 conference: Prediction models for future clustered data without removing the random intercept: A Bayesian approach.
Tobias, T. J., Nielen, M., & van Nes, A. (2016). Return to oestrus caused by impaired feed intake; a case report. Abstract from 24th International Pig Veterinary Society Congress & 8th European Symposium of Porcine Health Management, Dublin, Ireland.
2015
Scholarly publications
Ni, H., Klugkist, I. G., Rietbergen, C., Back, W., & Nielen, M. (2015). Including Variable Historical Information in the Analysis of Clinical Trials: an Application of Bayesian Power Prior Modelling. In SVEPM 2015 conference proceedings
van der Drift, S. G. A., Houweling, M., Bouman, M., Koets, A. P., Tielens, A. G. M., Nielen, M., & Jorritsma, R. (2015). Effects of a single glucocorticoid injection on propylene glycol-treated cows with clinical ketosis. Veterinary Journal, 204(2), 144-149. https://doi.org/10.1016/j.tvjl.2015.01.016
Holm, D. E., Nielen, M., Jorritsma, R., Irons, P. C., & Thompson, P. N. (2015). Evaluation of pre-breeding reproductive tract scoring as a predictor of long term reproductive performance in beef heifers. Preventive Veterinary Medicine, 118(1), 56-63. https://doi.org/10.1016/j.prevetmed.2014.10.016
2014
Scholarly publications
Higler, M. H., Brommer, H., L'Ami, J. J., de Grauw, J. C., Nielen, M., van Weeren, P. R., Laverty, S., Barneveld, A., & Back, W. (2014). The effects of three-month oral supplementation with a nutraceutical and exercise on the locomotor pattern of aged horses. Equine Veterinary Journal, 46(5), 611-617. https://doi.org/10.1111/evj.12182
Schmidt, A. F., Groenwold, R. H. H., Knol, M. J., Hoes, A. W., Nielen, M., Roes, K. C. B., De Boer, A., & Klungel, O. H. (2014). Exploring interaction effects in small samples increases rates of false-positive and false-negative findings: Results from a systematic review and simulation study. Journal of Clinical Epidemiology, 67(7), 821-829. https://doi.org/10.1016/j.jclinepi.2014.02.008
van Hulzen, K., Koets, A., Nielen, M., Heuven, H., Arendonk, J. A., & Klinkenberg, D. (2014). The effect of genetic selection for Johne's disease resistance in dairy cattle: Results of a genetic-epidemiological model. Journal of Dairy Science, 97(3), 1762-1773. https://doi.org/10.3168/jds.2013-7032
Schmidt, A. F., Klugkist, I., Klungel, O. H., Nielen, M., de Boer, A., Hoes, A. W., & Groenwold, R. H. H. (2014). Bayesian methods including nonrandomized study data increased the efficiency of postlaunch RCTs. Journal of Clinical Epidemiology, 68(4), 387-396. Article 8758. https://doi.org/10.1016/j.jclinepi.2014.11.015
Benedictus, L., Otten, H. G., van Schaik, G., van Ginkel, W. G., Heuven, H. C., Nielen, M., Rutten, V. P., & Koets, A. P. (2014). Bovine Neonatal Pancytopenia is a heritable trait of the dam rather than the calf and correlates with the magnitude of vaccine induced maternal alloantibodies not the MHC haplotype. Veterinary Research, 45, Article 45:129. https://doi.org/10.1186/s13567-014-0129-0
Hogerwerf, L., Koop, G., Klinkenberg, D., Roest, H. I. J., Vellema, P., & Nielen, M. (2014). Test and cull of high risk Coxiella burnetii infected pregnant dairy goats is not feasible due to poor test performance. Veterinary Journal, 200(2), 343-345. https://doi.org/10.1016/j.tvjl.2014.02.015
2013
Scholarly publications
Schmidt, A. F., Rovers, M. M., Klungel, O. H., Hoes, A. W., Knol, M. J., Nielen, M., De Boer, A., & Groenwold, R. H. H. (2013). Differences in interaction and subgroup-specific effects were observed between randomized and nonrandomized studies in three empirical examples. Journal of Clinical Epidemiology, 66(6), 599-607. https://doi.org/10.1016/j.jclinepi.2012.08.008
Schmidt, A. F., Groenwold, R. H. H., Pocock, S., Gueyffier, F., Hoes, A. W., De Boer, A., Nielen, M., & Klungel, O. H. (2013). Comparing effectiveness estimates from randomized and nonrandomized studies, using subgroup analyses and individual patient data. Pharmacoepidemiology and Drug Safety, 22, 29-30.
Maas, M., Keet, D. F., & Nielen, M. (2013). Hematologic and serum chemistry reference intervals for free-ranging lions (Panthera leo). Research in Veterinary Science, 95(1), 266-268. https://doi.org/10.1016/j.rvsc.2013.01.023
Koop, G., Collar, C. A., Toft, N., Nielen, M., van Werven, T., Bacon, D. A. C., & Gardner, I. A. (2013). Risk factors for subclinical intramammary infection in dairy goats in two longitudinal field studies evaluated by Bayesian logistic regression. Preventive Veterinary Medicine, 108(4), 304-312. https://doi.org/10.1016/j.prevetmed.2012.11.007
Maas, M., Keet, D. F., & Nielen, M. (2013). Hermatologic and serum chemistry reference intervals for free-ranging lions (Panthera leo). Research in Veterinary Science, 1, 266-268. https://doi.org/10.1016/j.rvsc.2013.01.023.
for the V.S.S.O. Investigators (2013). Prognostic factors of early metastasis and mortality in dogs with appendicular osteosarcoma after receiving surgery: an individual patient data meta-analysis. Preventive Veterinary Medicine, 112(3-4), 414-422. https://doi.org/10.1016/j.prevetmed.2013.08.011
Hogerwerf, L., Courcoul, A., Klinkenberg, D., Beaudeau, F., Vergu, E., & Nielen, M. (2013). Dairy goat demography and Q fever infection dynamics. Veterinary Research, 44(28), 1-13. https://doi.org/10.1186/1297-9716-44-28
Jones, B. A., Sauter-Louis, C., Henning, J., Stoll, A., Nielen, M., van Schaik, G., Smolenaars, A., Schouten, M., den Uijl, I., Fourichon, C., Guatteo, R., Madouasse, A., Nusinovici, S., Deprez, P., de Vliegher, S., Laureyns, J., Booth, R., Cardwell, J. M., & Pfeiffer, D. U. (2013). Calf-Level Factors Associated with Bovine Neonatal Pancytopenia – A Multi-Country Case-Control Study. PLoS One, 8(12), 1-9. Article e80619. https://doi.org/10.1371/journal.pone.0080619
Eisenberg, S. W. F., Chuchaisangrat, R., Nielen, M., & Koets, A. P. (2013). Relationship between Presence of Cows with Milk Positive for Mycobacterium avium subsp. paratuberculosis-Specific Antibody by Enzyme-Linked Immunosorbent Assay and Viable M. avium subsp. paratuberculosis in Dust in Cattle Barns. Applied and Environmental Microbiology, 79(18), 5458-5464. https://doi.org/10.1128/AEM.01187-13
Popularising publications
Nielen, M. (2013). Beter onderbouwd beslissen. Vetgedrukt, TvD en Veearts ( Agrimedia).
Other output
Benedictus, L., Rutten, V., Nielen, M., van Schaik, G., Heuven, H., & Koets, A. (2013). Bovine Neonatal Pancytopenia is a heritable trait for dams. Poster session presented at 10th International Veterinary Immunology Symposium (IVIS), Milan, Netherlands.
https://dspace.library.uu.nl/bitstream/handle/1874/415537/LB130812_IVIS_Poster_BNP4.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/415537/LB130812_IVIS_Poster_BNP4.pdf?sequence=1
Nielen, M. (2013). Beter onderbouwd beslissen. Utrecht University.
2012
Scholarly publications
Boerman, I., Selvarajah, G. T., Nielen, M., & Kirpensteijn, J. (2012). Prognostic factors in canine appendicular osteosarcoma – a meta-analysis. BMC Veterinary Research, 8(56), 10.1186/1746-6148-8-56. https://doi.org/10.1186/1746-6148-8-56
Sanchez-Vazquez, M. J., Nielen, M., Gunn, G. J., & Lewis, F. I. (2012). National monitoring of Ascaris suum related liver pathologies in English abattoirs: A time-series analysis, 2005–2010. Veterinary Pathology, 184(1), 83-87. https://doi.org/10.1016/j.vetpar.2011.08.011
Sanchez-Vazquez, M. J., Nielen, M., Gunn, G. J., & Lewis, F. I. (2012). Using seasonal-trend decomposition based on loess (STL) to explore temporal patterns of pneumonic lesions in finishing pigs slaughtered in England, 2005–2011. Preventive Veterinary Medicine, 104, 65-73. https://doi.org/10.1016/j.prevetmed.2011.11.003
Koop, G., Toft, N., Gardner, I. A., van Werven, T., & Nielen, M. (2012). Bayesian logistic regression model of risk factors for subclinical intramammary infection in dairy goats. In Proceedings of the SVEPM annual meeting 2012
van der Drift, S. G. A., van Hulzen, K. J. E., Teweldemedhn, T. G., Jorritsma, R., Nielen, M., & Heuven, H. C. M. (2012). Genetic and nongenetic variation in plasma and milk β-hydroxybutyrate and milk acetone concentrations of early-lactation dairy cows. Journal of Dairy Science, 95(11), 6781-6787. https://doi.org/10.3168/jds.2012-5640
Koop, G., Visscher, A., Collar, C. A., Bacon, D. A. C., Maga, E. A., Murray, J. D., Supré, K., de Vliegher, S., Haesebrouck, F., Rowe, J. D., Nielen, M., & van Werven, T. (2012). Short communication: Identification of coagulase-negative staphylococcus species from goat milk with the API Staph identification test and with transfer RNA-intergenic spacer PCR combined with capillary electrophoresis. Journal of Dairy Science, 95, 7200-7205. https://doi.org/10.3168/jds.2012-5747
Koop, G., de Vliegher, S. P., Visscher, A., Supré, K., Haesebrouck, F., Nielen, M., & van Werven, T. (2012). Differences between coagulase-negative Staphylococcus species in persistence and in effect on somatic cell count and milk yield in dairy goats. Journal of Dairy Science, 95(9), 5075-5084. https://doi.org/10.3168/jds.2012-5615
Koop, G., Nielen, M., & van Werven, T. (2012). Diagnostic tools to monitor udder health in dairy goats. Veterinary Quarterly, 32(1), 37-44. https://doi.org/10.1080/01652176.2012.675634
Opsteegh, M., Hogerwerf, L., Nooijen, S., Dam-Deisz, W. D. C., de Heer, L., Reusken, C., Bouma, A., Roest, H. J., Nielen, M., & van der Giessen, J. (2012). Experimental Inoculation of Male Rats with Coxiella burnetii: Successful Infection but No Transmission to Cage Mates. Applied and Environmental Microbiology, 78(16), 5661-5665. https://doi.org/10.1128/AEM.01169-12.
Butler, C. M., Sloet van Oldruitenborgh-Oosterbaan, M. M., Stout, T., van der Kolk, J. H., van den Wollenberg, L., Nielen, M., Jongejan, F., Werners, A. H., & Houwers, D. J. (2012). Prevalence of the causative agents of equine piroplasmosis in the South West of The Netherlands and the identification of two autochthonous clinical Theileria equi infections. Veterinary Journal, 193(2), 381-385. https://doi.org/10.1016/j.tvjl.2011.12.014
Hogerwerf, L., Borlée, F., Still, K., Heederik, D., van Rotterdam, B., de Bruin, A., Nielen, M., & Wouters, I. M. (2012). Detection of Coxiella burnetii DNA in Inhalable Airborne Dust Samples from Goat Farms after Mandatory Culling. Applied and Environmental Microbiology, 78(15), 5410-5412. https://doi.org/10.1128/AEM.00677-12
Eisenberg, S. W. F., Nielen, M., Hoeboer, J., Rutten, V. P., Heederik, D., & Koets, A. P. (2012). Environmental contamination with Mycobacterium avium subspecies paratuberculosis within and around a dairy barn under experimental conditions. Journal of Dairy Science, 95(11), 6477-6482. https://doi.org/10.3168/jds.2012-5548
Sanchez-Vazquez, M. J., Nielen, M., Edwards, S. A., Gunn, G. J., & Lewis, F. I. (2012). Identifying associations between pig pathologies using a multi-dimensional machine learning methodology. BMC Veterinary Research, 8(151), 1-11. https://doi.org/10.1186/1746-6148-8-151
Maas, M., Keet, D. F., Rutten, V. P. M. G., Heesterbeek, J. A. P., & Nielen, M. (2012). Assessing the impact of feline immunodeficiency virus and bovine tuberculosis co-infection in African lions. Proceedings of the Royal Society B-Biological Sciences, 279, 4206-4214. https://doi.org/10.1098/rspb.2012.1503
van Hulzen, K. J. E., Koets, A. P., Nielen, M., Hoeboer, J., van Arendonk, J. A. M., & Heuven, H. C. M. (2012). Genetic variation for infection status as determined by a specific antibody response against Mycobacterium avium subspecies paratuberculosis in milk of Dutch dairy goats. Journal of Dairy Science, 95(10), 6145-6151. https://doi.org/10.3168/jds.2012-5616
van Hulzen, K. J. E., Schopen, G. C. B., van Arendonk, J. A. M., Nielen, M., Koets, A. P., Schrooten, C., & Heuven, H. C. M. (2012). Genome-wide association study to identify chromosomal regions associated with antibody response to Mycobacterium avium subspecies paratuberculosis in milk of Dutch Holstein-Friesians. Journal of Dairy Science, 95(5), 2740-2748. https://doi.org/10.3168/jds.2011-5005
Eisenberg, S. W. F., Nielen, M., & Koets, A. P. (2012). Within-farm transmission of bovine paratuberculosis: recent developments. Veterinary Quarterly, 32(1), 31-35. https://doi.org/10.1080/01652176.2012.659870
Other output
Eisenberg, S., Koets, A., Nielen, M., Heederik, D., Mortier, R., De Buck, J., & Orsel, K. (2012). Intestinal infection of calves with mycobacterium avium subspecies paratuberculosis following aerosol challenge. Abstract from 11th International Colloquium on Paratuberculosis, Sydney, Australia.
Eisenberg, S., Koets, A., Nielen, M., Heederik, D., Mortier, R., De Buck, J., & Orsel, K. (2012). Calves infected with Mycobacterium avium subspecies paratuberculosis following intratracheal challenge. Abstract from 27th World Buiatrics Congress, Lisbon, Portugal.
Schmidt, A. F., Rovers, M. M., Klungel, O. H., Hoes, A. W., Knol, M. J., Nielen, M., De Boer, A., & Groenwold, R. H. H. (2012). Comparison of interaction and subgroup effects in observational studies and randomized clinical trials: Three empirical examples. Pharmacoepidemiology and Drug Safety, 21(S3), 127. Article 270. https://doi.org/10.1002/pds.3324
2011
Scholarly publications
Sanchez-Vazquez, M. J., Strachan, W. D., Armstrong, D., Nielen, M., & Gunn, G. J. (2011). The British pig health schemes: integrated systems for large-scale pig abattoir lesion monitoring. Veterinary Record, 10.1136/vr.d4814. https://doi.org/10.1136/vr.d4814
Hogerwerf, L., Brom, R., Roest, H. I. J., Bouma, A., Vellema, P., Pieterse, M. C., Dercksen, D., & Nielen, M. (2011). Reduction of Coxiella burnetii Prevalence by Vaccination of Goats and Sheep, the Netherlands. Emerging Infectious Diseases, 17(3), 379-386. https://doi.org/10.3201/eid1703.101157
van den Borne, B. H. P., Vernooij, J. C. M., Lupindu, A. M., van Schaik, G., Frankena, K., Lam, T. J. G. M., & Nielen, M. (2011). Relationship between somatic cell count status and subsequent clinical mastitis in Dutch dairy cows. Preventive Veterinary Medicine, 102, 265-273. https://doi.org/10.1016/j.prevetmed.2011.07.013
van Hulzen, K. J. E., Nielen, M., Koets, A. P., de Jong, G., van Arendonk, J. A. M., & Heuven, H. C. M. (2011). Effect of herd prevalence on heritability estimates of antibody response to Mycobacterium avium subspecies paratuberculosis. Journal of Dairy Science, 94, 992-997. https://doi.org/10.3168/jds.2010-3472
Courcoul, A., Monod, H., Nielen, M., Klinkenberg, D., Hogerwerf, L., Beaudeau, F., & Vergu, E. (2011). Modelling the effect of heterogeneity of shedding on the within herd Coxiella burnetii spread and identification of key parameters by sensitivity analysis. Journal of Theoretical Biology, 284, 130-141. https://doi.org/10.1016/j.jtbi.2011.06.017
Eisenberg, S. W., Koets, A. P., Nielen, M., Heederik, D., Mortier, R., Buck, J., & Orsel, K. (2011). Intestinal infection following aerosol challenge of calves with Mycobacterium avium subspecies paratuberculosis. Veterinary Research, 42(1), Article 117. https://doi.org/10.1186/1297-9716-42-117
Courcoul, A., Hogerwerf, L., Klinkenberg, D., Nielen, M., Vergu, E., & Beaudeau, F. (2011). Modelling effectiveness of herd level vaccination. Veterinary Research, 42(68), 10.1186/1297-9716-42-68. https://doi.org/10.1186/1297-9716-42-68
Eisenberg, S. W., Nielen, M., Hoeboer, J., Bouman, M., Heederik, D., & Koets, A. P. (2011). Mycobacterium avium subspecies paratuberculosis in bioaerosols after depopulation and cleaning of two cattle barns. Veterinary Record, 168(22), 10.1136/vr.d1091. https://doi.org/10.1136/vr.d1091
van Hulzen, K. J. E., Heuven, H. C. M., Nielen, M., Hoeboer, J., Santema, W. J., & Koets, A. P. (2011). Different Mycobacteriumavium subsp. paratuberculosis MIRU–VNTR patterns coexist within cattle herds. Veterinary Microbiology, 148, 419-424.
Koop, G., van Werven, T., Toft, N., & Nielen, M. (2011). Estimating test characteristics of somatic cell count to detect Staphylococcus aureus-infected dairy goats using latent class analysis. Journal of Dairy Science, 94, 2902-2911. https://doi.org/10.3168/jds.2010-3929
Professional publications
Roest, H. I. J., Hogerwerf, L., Brom, R., Oomen, T., van Steenbergen, J. E., Nielen, M., & Vellema, P. (2011). Q-koorts in Nederland: stand van zaken, resultaten van veterinair onderzoek en verwachtingen voor de komende jaren. Tijdschrift voor Diergeneeskunde, 136(5), 340-343.
https://dspace.library.uu.nl/bitstream/handle/1874/228049/2011_121.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/228049/2011_121.pdf?sequence=1
2010
Scholarly publications
Weber, M. F., Kogut, J., de Bree, J., van Schaik, G., & Nielen, M. (2010). Age at which dairy cattle become Mycobacterium avium subsp. paratuberculosis faecal culture positive. Preventive Veterinary Medicine, 97(1), 29-36. https://doi.org/10.1016/j.prevetmed.2010.07.004
van den Borne, B. H. P., van Schaik, G., Lam, T. J. G. M., & Nielen, M. (2010). Variation in herd level mastitis indicators between primi- and multiparae in Dutch dairy herds. Preventive Veterinary Medicine, 96(1-2), 49-55. https://doi.org/10.1016/j.prevetmed.2010.05.010
Vos, C. J., Nielen, M., Lopez, M., Elbers, A. R. W., & Dekker, A. (2010). Probability of exporting infected carcasses from vaccinated pigs following a foot-and-mouth disease epidemic. Risk Analysis, 30, 605-618.
Bouwstra, R. J., Nielen, M., Newboldt, J. R., Jansen, E. H. J. M., Jelinek, H. F., & van Werven, T. (2010). Vitamin E supplementation during the dry period in dairy cattle. Part II: Oxidative stress following vitamin E supplementation may increase clinical mastitis incidence postpartum. Journal of Dairy Science, 93(12), 5696-5706.
Eisenberg, S. W. F., Nielen, M., Santema, W. I., Houwers, D. J., Heederik, D., & Koets, A. P. (2010). Detection of spatial and temporal spread of Mycobacterium avium subsp. paratuberculosis in the environment of a cattle farm through bio-aerosols. Veterinary Microbiology, 143(2-4), 284-292. https://doi.org/10.1016/j.vetmic.2009.11.033
Eisenberg, S. W. F., Koets, A. P., Hoeboer, J., Bouman, M., Heederik, D., & Nielen, M. (2010). Presence of Mycobacterium avium subsp. paratuberculosis in Environmental Samples Collected on Commercial Dutch Dairy Farms. Applied and Environmental Microbiology, 76(18), 6310–6312. https://doi.org/10.1128/AEM.00998-10
van den Borne, B. H. P., Nielen, M., van Schaik, G., Melchior, M. B., Lam, T. J. G. M., & Zadoks, R. N. (2010). Host adaptation of bovine Staphylococcus aureus seems associated with bacteriological cure after lactational antimicrobial treatment. Journal of Dairy Science, 93(6), 2550-2558. https://doi.org/10.3168/jds.2009-2971
Koop, G., Dik, N., Nielen, M., & Lipman, L. J. A. (2010). Repeatability of differential goat bulk milk culture and associations with somatic cell count, total bacterial count, and standard plate count. Journal of Dairy Science, 93, 2569-2573. https://doi.org/10.3168/jds.2009-2705
Bouwstra, R. J., Nielen, M., Stegeman, A., Dobbelaar, P., Newboldt, J. R., Jansen, E. H. J. M., & van Werven, T. (2010). Vitamin E supplementation during the dry period in dairy cattle. Part I: Adverse effect on incidence of mastitis postpartum in a double-blind randomized field trial: adverse effect on incidence of mastitis postpartum in a double-blind randomized field trial. Journal of Dairy Science, 93(12), 5684-5695.
Halasa, T. H. B., Nielen, M., van Werven, T., & Hogeveen, H. (2010). A simulation model to calculate costs and benefits of dry period interventions in dairy cattle. Livestock Science, 129(1-3), 80-87. https://doi.org/10.1016/j.livsci.2010.01.009
Jirawattanapong, P., Stockhofe-Zurwieden, N., van Leengoed, L. A. M. G., Wisselink, H. J., Raymakers, R., van der Peet-Schwering, C. M. C., Cruijsen, A. L. M., Nielen, M., & van Nes, A. (2010). Pleuritis in slaughter pigs: Relations between lung lesions and bacteriology in 10 herds with high pleuritis. Research in Veterinary Science, 88, 11-15. https://doi.org/10.1016/j.rvsc.2009.06.007
Ellis-Iversen, J., Cook, A. J. C., Watson, E., Nielen, M., Larkin, L., Woolridge, M., & Hogeveen, H. (2010). Perceptions, circumstances and motivators that influence implementation of zoonotic control programs on cattle farms. Preventive Veterinary Medicine, 93, 276-285.
van den Borne, B. H. P., van Schaik, G., Lam, T. J. G. M., & Nielen, M. (2010). Therapeutic effects of antimicrobial treatment during lactation of recently acquired bovine subclinical mastitis: Two linked randomized field trials. Journal of Dairy Science, 93(1), 218-233.
Sanchez-Vazquez, M. J., Smith, R. P., Kang, S., Lewis, F., Nielen, M., Gunn, G. J., & Edwards, S. A. (2010). Identification of factors influencing the occurrence of milk spot livers in slaughtered pigs: A novel approach to understanding Ascaris suum epidemiology in British farmed pigs. Veterinary Parasitology, 173(3-4), 271-279. https://doi.org/10.1016/j.vetpar.2010.06.029
Mulatti, P., Bos, M. E. H., Busani, L., Nielen, M., & Marangon, S. (2010). Evaluation of interventions and vaccination strategies for low pathogenicity avian influenza: spatial and space-time analyses and quantification of the spread of infection. Epidemiology and Infection, 138, 813-824. https://doi.org/10.1017/S0950268809991038
Bos, M. E. H., Nielen, M., Toson, M., Comin, A., Marangon, S., & Busani, L. (2010). Within-flock transmission of H7N1 highly pathogenic avian influenza virus in turkeys during the Italian epidemic in 1999–2000. Preventive Veterinary Medicine, 95, 297-300. https://doi.org/10.1016/j.prevetmed.2010.04.006
Koop, G., van Werven, T., Schuiling, H. J., & Nielen, M. (2010). The effect of subclinical mastitis on milk yield in dairy goats. Journal of Dairy Science, 93(12), 5809-5817. https://doi.org/10.3168/jds.2010-3544
Koets, A. P., Santema, W. J., Mertens, H., Oostenrijk, D. A. M., Keestra, M., Overdijk, M., Labouriau, R., Franken, P., Frijters, A., Nielen, M., & Rutten, V. P. M. G. (2010). Susceptibility to paratuberculosis infection in cattle is associated with single nucleotide polymorphisms in Toll-like receptor 2 which modulate immune responses against Mycobacterium avium subspecies paratuberculosis. Preventive Veterinary Medicine, 93, 305-315. https://doi.org/10.1016/j.prevetmed.2009.11.008
van den Borne, B. H. P., Halasa, T. H. B., van Schaik, G., Hogeveen, H., & Nielen, M. (2010). Bioeconomic modeling of lactational antimicrobial treatment of new bovine subclinical intramammary infections caused by contagious pathogens. Journal of Dairy Science, 93(9), 4034-3030. https://doi.org/10.3168/jds.2009-3030
https://dspace.library.uu.nl/bitstream/handle/1874/204523/47.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/204523/47.pdf?sequence=1
Other output
Eisenberg, S., Koets, A., & Nielen, M. (2010). Presence of viable Mycobacterium avium subsp. paratuberculosis in dust samples collected on commercial dairy farms. Abstract from 26th World Buiatrics Congress, Santiago de Chile, Chile.
van Hulzen, K. J. E., Nielen, M., Koets, A. P., de Jong, G., van Arendonk, J. A. M., & Heuven, H. C. M. (2010). Within herd test prevalence affects genetic variation in antibody response to Mycobacterium avium subspecies paratuberculosis in milk of Dutch Holstein-Friesians. Abstract from Unknown event.
https://dspace.library.uu.nl/bitstream/handle/1874/309981/herd.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/309981/herd.pdf?sequence=1
2009
Scholarly publications
Halasa, T., Nielen, M., De Roos, A. P. W., Van Hoorne, R., De Jong, G., Lam, T. J. G. M., Van Werven, T., & Hogeveen, H. (2009). Erratum: Production loss due to new subclinical mastitis in Dutch dairy cows estimated with a test-day model (Journal of Dairy Science 92 (599-606)). Journal of Dairy Science, 92(3). https://doi.org/10.3168/jds.2009-92-3-1315
Melchior, M. B., van Osch, M. H. J., Graat, R. M., van Duijkeren, E., Mevius, D. J., Nielen, M., Gaastra, W., & Fink-Gremmels, J. (2009). Biofilm formation and genotyping of Staphylococcus aureus bovine mastitis isolates: evidence for lack of penicillin-resistance in Agr-type II strains. Veterinary Microbiology, 137(1-2), 83-89.
Bos, M. E. H., Nielen, M., Koch, G., Bouma, A., de Jong, M. C. M., & Stegeman, A. (2009). Back-calculation method shows that within-flock transmission of highly pathogenic avian influenza (H7N7) virus in the Netherlands is not influenced by housing risk factors. Preventive Veterinary Medicine, 88, 278-285.
Halasa, T. H. B., Østerås, O., Hogeveen, H., van Werven, T., & Nielen, M. (2009). Meta-Analysis of Dry Cow Management for Dairy Cattle. Part 1. Protection Against New Intramammary Infections. Journal of Dairy Science, 92(7), 3134-3149.
Bouwstra, R. J., Nielen, M., & van Werven, T. (2009). Comparison of the oxidative status of Vitamin E-supplemented and non-supplemented cows under field conditions. Tijdschrift voor Diergeneeskunde, 134(16), 656-661.
Halasa, T. H. B., Nielen, M., de Roos, A. P. W., van Hoorne, R., de Jong, G., Lam, T. J. G. M., van Werven, T., & Hogeveen, H. (2009). Production loss due to new subclinical mastitis in Dutch diary cows estimated with a test-day model. Journal of Dairy Science, 92, 599-606.
https://dspace.library.uu.nl/bitstream/handle/1874/39375/53.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/39375/53.pdf?sequence=1
Koop, G., Nielen, M., & van Werven, T. (2009). Bulk milk somatic cell counts are related to bulk milk total bacterial counts and several herd-level risk factors in dairy goats. Journal of Dairy Science, 92, 4355-4364.
Halasa, T. H. B., Nielen, M., Huirne, R. B. M., & Hogeveen, H. (2009). Stochastic bio-economic model of bovine intramammary infection. Livestock Science, 124, 295-301.
Tiensin, T., Ahmed, S. S. U., Rojanasthien, S., Songserm, T., Ratanakorn, P., Chaichoun, K., Kalpravidh, W., Wongkasemjit, S., Patchimasiri, T., Chanachai, K., Thanapongtham, W., Chotinan, S., Stegeman, A., & Nielen, M. (2009). Ecologic risk factor investigation of clusters of Avian Influenza A (H5N1) virus infection in Thailand. Journal of Infectious Diseases, 199, 1735-1743.
https://dspace.library.uu.nl/bitstream/handle/1874/39500/18.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/39500/18.pdf?sequence=1
Ellis-Iversen, J., Pritchard, G. C., Wooldridge, M. J., & Nielen, M. (2009). Risk factors for Campylobacter jejuni and Campylobacter coli in young cattle on English and Welsh farms. Preventive Veterinary Medicine, 88, 42-48.
Merton, J. S., Ask, B. A., Onkundi, D. C., Mullaart, E., Colenbrander, B., & Nielen, M. (2009). Genetic parameters for oocyte number and embryo production within a bovine ovum pick-up–in vitro production embryo-production program. Theriogenology, 72, 885-893.
Halasa, T. H. B., Nielen, M., Whist, A. C., & Østerås, O. (2009). Meta-Analysis of Dry Cow Management for Dairy Cattle. Part 2. Cure of Existing Intramammary Infections. Journal of Dairy Science, 92(7), 3150-3157.
Other output
Eisenberg, S., Nielen, M., Hoeboer, J., Heederik, D., & Koets, A. (2009). Relation between fecal shedders and environmental contamination with Mycobacterium aviumsubsp. paratuberculosis on an experimental farm. Abstract from 10th International Colloquium on Paratuberculosis, Minneapolis, United States.
2008
Scholarly publications
Jirawattanapong, P., Stockhofe-Zurwieden, N., van Leengoed, L. A. M. G., Binnendijk, G. P., Wisselink, H. J., Raymakers, R., Cruijsen, A. L. M., van der Peet-Schwering, C. M. C., van Nes, A., & Nielen, M. (2008). Efficacy of a subunit vaccine Actinobacillus pleuropneumoniae in an endemically infected swine herd. Journal of Swine Health and Production, 16(4), 193-199.
https://dspace.library.uu.nl/bitstream/handle/1874/32090/40.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/32090/40.pdf?sequence=1
Bos, M. E. H., Nielen, M., Koch, G., Stegeman, A., & Jong, M. C. M. (2008). Effect of H7N1 vaccination on highly pathogenic avian influenza H7N7 virus transmission in turkeys. Vaccine, 26, 6322-6328.
https://dspace.library.uu.nl/bitstream/handle/1874/32196/62.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/32196/62.pdf?sequence=1
Bouwstra, R. J., Goselink, R. M. A., Dobbelaar, P., Nielen, M., Newbold, J. R., & van Werven, T. (2008). The Relationship Between Oxidative Damage and Vitamin E Concentration in Blood, Milk, and Liver Tissue from Vitamin E Supplemented and Nonsupplemented Periparturient Heifers. Journal of Dairy Science, 91, 977-987.
https://dspace.library.uu.nl/bitstream/handle/1874/32043/17.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/32043/17.pdf?sequence=1
Weber, M. F., Nielen, M., Velthuis, A. G. J., & van Roermund, H. J. W. (2008). Milk quality assurance for paratuberculosis: simulation of within-herd infection dynamics and economics. Veterinary Research, 39(2), 12. https://doi.org/10.1051/vetres:2007050
https://dspace.library.uu.nl/bitstream/handle/1874/32044/18.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/32044/18.pdf?sequence=1
Professional publications
Van Den Borne, B. H. P., Van Schaik, G., Lam, T. J. G. M., & Nielen, M. (2008). A comparison of the occurrence of mastitis in Dutch primi- and multiparous cows. In Mastitis Control: From Science to Practice (pp. 55-62). Wageningen Academic Publishers. https://doi.org/10.3920/978-90-8686-649-6
2007
Scholarly publications
Maurice, H., Nielen, M., Vyt, P., Frankena, K., & Koenen, F. (2007). Factors related to the incidence of clinical encephalomyocarditis virus (EMCV) infection on Belgian pig farms. Preventive Veterinary Medicine, 78, 24-34.
Weber, M. F., Nielen, M., Verhoeff, J., & Stegeman, J. A. (2007). Certification and surveillance programmes for paratuberculosis in dairy herds. In Proceedings of the 19th annual meeting of the VEEC (pp. 47-54)
Swildens, B., Nielen, M., Wisselink, H. J., Verheijden, J. H. M., & Stegeman, J. A. (2007). Elimination of strains of Streptococcus suis serotype 2 from the tonsils of carrier sows by combined medication and vaccination. Veterinary Record, 160, 619-621.
Kivaria, F. M., Noordhuizen, J. P. T., & Nielen, M. (2007). Interpretation of California Mastitis Test scores using Staphylococcus aureus culture results for screening of subclinical mastitis in low yielding smallholder dairy cows in the Dar es Salaam region of Tanzania. Preventive Veterinary Medicine, 78, 274-285.
Bos, M. E. H., van Boven, R. M., Nielen, M., Bouma, A., Elbers, A. R. W., Nodelijk, G., Koch, G., Stegeman, J. A., & de Jong, M. C. M. (2007). Estimating the day of highly pathogenic avian influenza (H7N7) virus introduction into a poultry flock based on mortality data. Veterinary Research, 38, 493-504.
Tiensin, T., Nielen, M., Vernooij, J. M. C., Songserm, T., Chotiprasatintara, S., Kalpravidh, W., Chaisingh, A., Wongkasemjit, S., Chanachai, K., Thanapongtham, W., Srisuvan, T., & Stegeman, J. A. (2007). Quantification of within-flock transmission of H5N1 avian influenza in chicken flocks in Thailand. In Proceedings of the Society for Veterinary Epidemiology and Preventive Medicine (SVEPM) conference (pp. 246-257)
Tiensin, T., Nielen, M., Vernooij, J. C. M., Songserm, T., Kalpravidh, W., Chotiprasatintara, S., Chaisingh, A., Wongkasemjit, S., Chanachai, K., Thanapongtham, W., Srisuvan, T., & Stegeman, J. A. (2007). Transmission of the highly pathogenic avian influenza H5N1 virus within flocks during the 2004 epidemic in Thailand. Journal of Infectious Diseases, 196, 1679-1684. https://doi.org/10.1086/522007
Tiensin, T., Nielen, M., Songserm, T., Kalpravidh, W., Chaitaweesub, P., Amonsin, A., Chotiprasatintara, S., Chaisingh, A., Damrongwatnapokin, S., Wongkasemjit, S., Antarasena, C., Songkitti, V., Chanachai, K., Thanapongtham, W., & Stegeman, J. A. (2007). Geographic and temporal distribution of highly pathogenic avian influenza A virus (H5N1) in Thailand, 2004-2005: an overview. Avian Diseases, 51, 182-188. https://doi.org/10.1637/7635-042806R.1
Bouma, A., Tiensin, T., Claassen, I., Nielen, M., van Boven, R. M., & Stegeman, A. (2007). Estimation of the critical proportion of chickens in a flock tob e immunized in order to prevent major outbreaks of HPAI H5N1. In Abstract of Vaccination: a tool for the control of Avian Influenza, An OIE/FAO/IZSVe scientific conference (pp. 60-60)
2006
Scholarly publications
de Vos, C. J., Saatkamp, H. W., Nielen, M., & Huirne, R. B. M. (2006). Sensitivity analysis to evaluate the impact of uncertain factors in a scenario tree model for classical swine fever introduction. Risk Analysis, 26(5), 1311-1322.
Nielen, M., Kruitwagen, C. L. J. J., & Beynen, A. C. (2006). Effect of vitamin E supplementation on udder health; a meta-analysis. In Proceedings of SVEPM Annual Conference (pp. 119-128)
Augustijn, M., Elbers, A. R. W., Koenen, F., & Nielen, M. (2006). Estimation of seroprevalence of encephalomyocarditis in Dutch sow herds using the virus neutralization test. Tijdschrift voor Diergeneeskunde, 131(2), 40-44.
Weber, M. F., van Roermund, H. J. W., Velthuis, A. G. J., de Koeijer, A. A., de Jong, M. C., & Nielen, M. (2006). Stochastic simulation of a milk quality assurance programme for paratuberculosis: within herd infection dynamics and economics. In Proceedings SVEPM (pp. 25-38)
Kluivers, M., Maurice, H., Vyt, P., Koenen, F., & Nielen, M. (2006). Transmission of encephalomyocarditis virus in pigs estimated from field data in Belgium by means of R0. Veterinary Research, 26(5), 1311-1322.
2005
Scholarly publications
Thomas, M. E., Bouma, A., Ekker, H. M., Fonken, A. J. M., Stegeman, J. A., & Nielen, M. (2005). Risk factors for the introduction of high pathogenicity Avian Influenza virus into poultry farms during the epidemic in the Netherlands in 2003. Preventive Veterinary Medicine, 69(1-2), 1-11. https://doi.org/10.1016/j.prevetmed.2004.12.001
Swildens, B., Wisselink, H. J., Engel, B., Smith, H., Nielen, M., Verheijden, J. H. M., & Stegeman, J. A. (2005). Detection of EF-positive Streptococcus suis serotype 2 strains in tonsillar swabs of love sows. Veterinary Microbiology, 109, 223-228. https://doi.org/10.1016/j.vetmic.2005.04.024
Klinkenberg, D., Nielen, M., Mourits, M. C. M., & de Jong, M. C. M. (2005). The effectiveness of classical swine fever surveillance programmes in The Netherlands. Preventive Veterinary Medicine, 67, 19-37.
Swildens, B., Engel, B., Stegeman, J. A., & Nielen, M. (2005). Test characteristics of a PCR for streptococcus suis analysed in a Bayesian model. In Proceedings of the 17th annual meeting of the VEEC (pp. 27-31).
Tiensin, T., Chaitaweesup, P., Songserm, T., Chaising, A., Hoonsuwan, W., Buranathai, C., Parakamawongsa, T., Premashtira, S., Amonsin, A., Gilbert, M., Nielen, M., & Stegeman, J. A. (2005). Highly pathogenic Avian Influenza H5N1. Emerging Infectious Diseases, 11, 1664-1672. https://doi.org/10.3201/eid1111.050608
Swildens, B., Engel, B., Stegeman, J. A., & Nielen, M. (2005). Test characteristics of a PCR for streptococcus suis defined by Bayesian analysis. In D. Mellor (Ed.), Proceedings of the meeting of the SVEPM (pp. 147-154).
Tsai, P. S., Nielen, M., van der Horst, G. T. J., Colenbrander, B. A., Heesterbeek, J. A. P., & Fentener-van Vlissingen, J. M. (2005). The effect of DNA repair defects on reproductive performance in Nucleotide Excision Repair (NER) mouse models: an epidemiological approach. Transgenic Research, 14, 845-857. https://doi.org/10.1007/s11248-005-1772-z
Maurice, H., Nielen, M., Brocchi, E., Nowotny, N., Kassimi, L. B., Billinis, C., Loukaides, P., O'Hara, R. S., & Koenen, F. (2005). The occurrence of encephalomyocarditis virus (EMCV) in European pigs from 1990 to 2001. Epidemiology and Infection, 133(3), 547-557.
Weber, M., van Roermund, H. J. W., Velthuis, A. G. J., de Koeijer, A. A., de Jong, M. C. M., & Nielen, M. (2005). Development of a milk quality assurance programme for paratuberculosis: Stochastic silumation of within-herd infection dynamics and economics. In Proceedings of the 8th International Colloquium for Paratuberculosis (pp. 1-2).
de Vos, C., Saatkamp, H. W., Nielen, M., & Huirne, R. B. M. (2005). Sensitivity analysis to evaluate the impact of uncertain factors in a scenario tree model for classical swine fever introduction. In Proceedings of the OR, Applications in Health and Life-Sciences (pp. 1-2).
Moyo, N., Nielen, M., Kruitwagen, C., & Beynen, A. C. (2005). Vitamin E supplementation and udder health: a meta-analysis. In Proceedings of the 4th IDF International Mastitis Conference
Thomas, M. E., Bouma, A., Ekker, H. M., Fonken, A. J., Stegeman, J. A., & Nielen, M. (2005). Risk factors for the introduction of high pathogenicity Avian Inlfuenza virus into poultry farms during the epidemic in the Netherlands in 2003. Preventive Veterinary Medicine, 69, 1-11.
Professional publications
Augustijn, M., Elbers, A. R. W., Koenen, F., & Nielen, M. (2005). Estimation of seroprevalence of encephalomyocarditis virus infections in swine in the Netherlands using the virus neutralization test. Tijdschrift voor Diergeneeskunde, 131(2), 40-44.
2004
Scholarly publications
Weber, M. F., Groenendaal, H., van Roermund, H. J. W., & Nielen, M. (2004). Simulation of alternatives for the Dutch Johne's disease certification-and-monitoring program. Preventive Veterinary Medicine, 62(1), 1-17. https://doi.org/10.1016/j.prevetmed.2003.11.006
Spyrou, V., Maurice, H., Billinis, C., Papanastassopoulou, M., Psalla, D., Nielen, M., Koenen, F., & Papadopoulos, O. (2004). Transmission and pathogenicity of encephalomyocarditis virus (EMCV) among rats. Veterinary Research, 35, 113-122.
Klinkenberg, D., Nielen, M., Mourits, M. C. M., & de Jong, M. C. M. (2004). An evaluation of the Dutch classical swine fever surveillance programme. In Proceedings 16e studiedag VEEC
Hartman, E. G., Frankena, K., Oude Vrielink, H. E., Nielen, M., Metz, J. H. M., & Huirne, R. B. M. (2004). Risk factors associated with sick leave due to work-related injuries in Dutch farmers: an exploratory case-control study. Safety Science, 42(9), 807-823.
Vonk Noordegraaf, A., Labrovic, A., Frankena, K., Pfeiffer, D. U., & Nielen, M. (2004). Simulated hazards of losing infection-free status in a Dutch BHV1 model. Preventive Veterinary Medicine, 62, 51-58.
Swildens, B., Stockhofe-Zurwieden, N., van der Meulen, J., Wisselink, H. J., Nielen, M., & Niewold, T. A. (2004). Intestinal translocation of Streptococcus suis type 2 EF* in pigs. Veterinary Microbiology, 103(1-2), 29-33.
de Vos, C. J., Saatkamp, H. W., Nielen, M., & Huirne, R. B. M. (2004). Scenario tree modeling to analyze the probability of classical swine fever introduction into member states of the European Union. Risk Analysis, 24(1), 237-253.
Klinkenberg, D., Nielen, M., Mourits, M. C. M., & de Jong, M. C. M. (2004). An evaluation of the Dutch classical swine fever surveillance programme. In S. W. J. Reid, F. D. Menzies, & A. M. Russell (Eds.), Proceedings of the SVEPM (pp. 85-92).
Mangen, M. J., Nielen, M., & Burrell, A. M. (2004). Simulated epidemiological and economic effects of measures to reduce piglet supply during a Classical Swine Fever epidemic in the Netherlands. Revue Scientifique et Technique - Office International des Epizooties, 22(3), 811-822.
2003
Scholarly publications
Crauwels, A. P., Nielen, M., Elbers, A. R. W., Stegeman, J. A., & Tielen, M. J. M. (2003). Neighbourhood infections of classical swine fever during the 1997-1998 epidemic in The Netherlands. Preventive Veterinary Medicine, 61(4), 263-277.
Vonk Noordegraaf, A., Nielen, M., & Kleijnen, J. P. C. (2003). Sensitivity analysis by experimental design and metamodelling: Case study on simulation in national animal disease control. European Journal of Operational Research, 146(3), 433-443.
Nodelijk, G., Nielen, M., de Jong, M. C. M., & Verheijden, J. H. M. (2003). A review of porcine reproductive and respiratory syndrome virus in Dutch breeding herds: population dynamics and clinical relevance. Preventive Veterinary Medicine, 60, 37-52.
Groenendaal, H., Nielen, M., & Hesselink, J. W. (2003). Development of the Dutch Johne's disease control program supported by a simulation model. Preventive Veterinary Medicine, 60(1), 69-90.
Vos, C. J., Saatkamp, H. W., Nielen, M., & Huirne, R. B. M. (2003). Risk assessment for classical swine fever introduction into The Netherlands. In Proc of the VEEC
Professional publications
van der Fels-Klerx, H. J., Martin, S., Nielen, M., & Huirne, R. B. M. (2003). Effects on productivity and risk factors of Bovine Respiratory Disease in dairy heifers; a review for the Netherlands. Netherlands Journal of Agricultural Science, 50(1), 27-45.
2002
Scholarly publications
Mangen, M. J., Burrell, A. M., & Nielen, M. (2002). Does pig density matter for the choice of control strategies in a classical swine fever epidemic? In Proceedings of the 10th EAAE Congress
Mangen, M. J., Burrell, A. M., & Nielen, M. (2002). Strategies to control Classical Swine Fever: cost and risk perspectives. In Proc 13th Int IFMA Congr of Farm Mangement
van Schaik, G., Schukken, Y. H., Nielen, M., Dijkhuizen, A. A., Barkema, H. W., & Benedictus, G. (2002). Probability of and risk factors for introduction of infectious diseases into Dutch SPF dairy farms: a cohort study. Preventive Veterinary Medicine, 54(3), 279-289.
Maurice, H., Nielen, M., Stegeman, J. A., Vanderhallen, H., & Koenen, F. (2002). Transmission of encephalomyocarditis virus (EMCV) among pigs experimentally quantified. Veterinary Microbiology, 88(4), 301-314.
Mangen, M. J., Burrell, A. M., & Nielen, M. (2002). Simulated effect of pig-population density on epidemics in the Netherlands. Preventive Veterinary Medicine, 56, 141-163.
Groenendaal, H., Nielen, M., Jalvingh, A. W., Horst, S. H., Galligan, D. T., & Hesselink, J. W. (2002). A simulation of Johne's disease control. Preventive Veterinary Medicine, 54(3), 225-245.
Mourits, M. C. M., Nielen, M., & Léon, C. D. (2002). Effect of control measures on the course of simulated FMD-epidemics that started at different farm types in various Dutch areas. In Proc of SVEPM Ann Conf (pp. 190-200).
Maurice, H., Vyt, P., Koenen, F., & Nielen, M. (2002). Studying an emerging pig disease, encephalomyocarditis, by means of a case-control study: mission impossible? In Proc of SVEPM Ann Conf (pp. 111-119).
Vonk Noordegraaf, A., Nielen, M., Franken, P., & Dijkhuizen, A. A. (2002). Simulation modeling of BHV1-control program at national level, with special attention to sensitivity analysis. Livestock Production Science, 76, 697-700.
Weber, M. F., Groenendaal, H., van Roermund, H. J. W., & Nielen, M. (2002). Simulation of alternatives for the Dutch Johne's disease certification programme. In Proc of SVEPM Ann Conf (pp. 178-188).
Noordegraaf, A. V., Nielen, M., Franken, P., & Dijkhuizen, A. A. (2002). Simulation modelling of BHV1-control programme at national level, with special attention to sensitivity analysis. Livestock Production Science, 76(1-2), 153-170.
Poelmans, S., de Wasch, K. G., de Brabander, H. F., van de Wiele, M., Courtheyn, D., van Ginkel, L. A., Sterk, S. S., Delahaut, P., Dubois, M., Schilt, R., Nielen, M., Vercammen, J., Impens, S. R., Stephany, R. W., Hamoir, T., Pottie, G., van Poucke, C., & van Peteghem, C. (2002). Analytical possibilities for the detection of stanozolol and its metabolites. Analytica Chimica Acta, 473, 39-47.
2001
Scholarly publications
van Schaik, G., Nielen, M., & Dijkhuizen, AA. (2001). An economic model for on-farm decision support of management to prevent infectious disease introduction into dairy farms. Preventive Veterinary Medicine. https://doi.org/10.1016/S0167-5877(01)00224-0
Vonk Noordegraaf, A., Nielen, M., & Kleijnen, J. P. C. (2001). Sensitivity analysis by experimental design and metamodeling for InterIBR-endemic. In Proc of SVEPM Annual Conference. (pp. 49-56)
Groenendaal, H., Nielen, M., & Hesselink, J. W. (2001). Development of the Dutch Johne's disease control program supported by a simulation model. In Proc of SVEPM Annual Conference (pp. 141-152).
Crauwels, A. P. P., de Koning, R., Nielen, M., Elbers, A. R. W., Dijkhuizen, A. A., & Tielen, M. J. M. (2001). A concept for a decision support system based on pratical experiences form a national disease emergency. The Dutch experience. Acta Veterinaria Scandinavica, 94, 61-69.
van Schaik, G., Schukken, Y. H., Nielen, M., Dijkhuizen, A. A., & Benedictus, G. (2001). Risk factors for introduction of BHV1 into BHV1-free Dutch dairy farms: a case-control study. Veterinary Quarterly, 23, 71-76.
van Schaik, G., Nielen, M., & Dijkhuizen, A. A. (2001). Biosecurity on dairy farms: the economic benefits. In Proc of SVEPM Annual Conference. (pp. 175-184)
van Schaik, G., Nielen, M., & Dijkhuizen, A. A. (2001). An ecomomic model for on-farm decision support of management to prevent infectious disease introduction into dairy farms. Preventive Veterinary Medicine, 51, 289-305.
Crauwels, A. P. P., Nielen, M., Elbers, A. R. W., Stegeman, J. A., & Tielen, M. J. M. (2001). Neighbourhood infections of classical swine fever during the 1997-1998 epidemic in the Netherlands. In Proc of the VEEC (pp. 69-76).
Mangen, M. J., Jalvingh, A. W., Nielen, M., Moutirs, M. C., Klinkenberg, D., & Dijkhuizen, A. A. (2001). Spatial and stochastic simulation to compare two emergency-vaccination strategies with a marker vaccine in the 1997/1998 Dutch Classical Swine Fever epidemic. Preventive Veterinary Medicine, 48, 177-200.
2000
Scholarly publications
Vanderhallen, H., Maurice, H., Koenen, F., & Nielen, M. (2000). Determination of the basic reproduction ratio (Ro) of a myocardia strain of Encephalomyocarditis Virus in european pigs. In Proceedings of 5th International Congress of the ESVV: Veterinary Virology in the New Millennium (pp. 161-162).
Maurice, H., Nielen, M., & Koenen, F. (2000). A project on Encephalomyocarditis Virus infections in European pig herds. In Proceedings of 9th Symposium ISVEE (pp. 703-705).
Groenendaal, H., Jalvingh, A. W., Nielen, M., & Horst, H. S. (2000). A simulation model to study the epidemiological and economic consequences of Johne's disease control programs. In Proceedings of 9th Symposium ISVEE, Breckenridge, Colorado (pp. 590-592)
Rathi, R., Nielen, M., Cheng, F. P., van Buiten, A., & Colenbrander, B. A. (2000). Exposure of progesterone receptors on the plasma membranes of stallion spermatozoa as a parameter for the prediction of fertility. Journal of reproduction and fertility. Supplement, 56, 87-91.
van Schaik, G., Schukken, Y. H., Nielen, M., Dijkhuizen, A. A., Barkema, H. W., & Benedictus, G. (2000). The economics of a more closed system to prevent introduction of infectious diseases into SPF diary herds. In The economics of a more closed system to prevent introduction of infectious diseases into SPF diary herds (pp. 198-200).
Lyimo, Z. C., Nielen, M., Ouweltjes, W., Kruip, T. A. M., & van Eerdenburg, F. J. C. M. (2000). Relationship among estradiol, cortisol and intensity of estrous behavior in diary cattle. In Proceedings of 10th International Congress on Animal Hygiene (pp. 482-485).
van Schaik, G., Schukken, Y. H., Nielen, M., Dijkhuizen, A. A., & Benedictus, G. (2000). The use of exact methods to obtain risk factors for introduction of BHV1 at BHV1-free diary farms-. In Proceedings of 9th Symposium of the ISVEE (pp. 511-513).
Groenendaal, H., Jalvingh, A. W., Nielen, M., & Horst, H. S. (2000). A simulation model to study the epidemiological and economic consequences of Johne's disease control programs. In Proceedings of the Symposium on Economic Modelling of Animal Health and Farm Management (pp. 203-205)
Suriyasathaporn, W., Schukken, Y. H., Nielen, M., & Brand, A. (2000). Low somatic cell count: a risk factor for subsequent Clinical mastitis in a dairy herd. Journal of Dairy Science, 83(6), 1248-1255.
Crauwels, A. P. P., Stegeman, J. A., Elbers, A. R. W., & Nielen, M. (2000). Airborne transmission as a mechanism underlying neighbourhood infections of Classical Swine Fever during the 1997 Epidemic in the Netherlands. In Proceedings of the 9th ISVEE (pp. 1124-1126)
Professional publications
Hessels, A. L. D., Poel, W. H. M., Nielen, M., Emmerzaal, A., & Schukken, Y. H. (2000). Heckrunderen in de Oostvaardersplassen: risico voor infectieziekten of niet? Tijdschrift voor Diergeneeskunde, 38-47.
Groenendaal, H., & Nielen, M. (2000). Aanvulling modelstudie voorbereiding bestrijding Para-tbc. Farm Management.
1999
Scholarly publications
Suriyasathaporn, W., Daemen, A. J. J. M., Noordhuizen-Stassen, E. N., Dieleman, S. J., Nielen, M., & Schukken, Y. H. (1999). β-Hydroxybutyrate levels in peripheral blood and ketone bodies supplemented in culture media affect the in vitro chemotaxis of bovine leukocytes. Veterinary Immunology and Immunopathology, 68(2-4), 177-186. https://doi.org/10.1016/S0165-2427(99)00017-3
Van Schaik, G., Schukken, Y. H., Nielen, M., Dijkhuizen, A. A., & Huime, R. B. M. (1999). Application of survival analysis to identify management factors related to the rate of BHV1 seroconversions in a retrospective study of Dutch dairy farms. Livestock Production Science, 60(2-3), 371-382. https://doi.org/10.1016/S0301-6226(99)00107-4
Van Schaik, G., Shoukri, M., Martin, S. W., Schukken, Y. H., Nielen, M., Hage, J. J., & Dijkhuizen, A. A. (1999). Modeling the Effect of an Outbreak of Bovine Herpesvirus Type 1 on Herd-Level Milk Production of Dutch Dairy Farms. Journal of Dairy Science, 82(5), 944-952. https://doi.org/10.3168/jds.S0022-0302(99)75313-0
Crauwels, A. P., Nielen, M., Stegeman, J. A., Elbers, A. R., Dijkhuizen, A. A., & Tielen, M. J. (1999). The effectiveness of routine serological surveillance: case study of the 1997 epidemic of classical swine fever in The Netherlands. Revue Scientifique et Technique - Office International des Epizooties, 18(3), 627-37.
Jalvingh, A. W., Nielen, M., Maurice, H., Stegeman, A. J., Elbers, A. R., & Dijkhuizen, A. A. (1999). Spatial and stochastic simulation to evaluate the impact of events and control measures on the 1997-1998 classical swine fever epidemic in The Netherlands. I. Description of simulation model. Preventive Veterinary Medicine, 42(3-4), 271-95.
Jalvingh, A. W., Nielen, M., Maurice, H., Stegeman, J. A., Elbers, A. R. W., & Dijkhuizen, A. A. (1999). Spatial and stochastic simulation to evaluate the impact of events and control measures on the 1997-1998 classical swine fever epedemic in The Netherlands: 1 Description of simulation model. Preventive Veterinary Medicine, 42(3-4), 271-295.
Nielen, M., Jalvingh, A. W., Meuwissen, M. P. M., Horst, S. H., & Dijkhuizen, A. A. (1999). Spatial and stochastic simulation to evaluate the impact of events and control measures on the 1997-1998 classical swine fever epidemic in The Netherlands : 2 Comparison of control strategies. Preventive Veterinary Medicine, 42(3-4), 297-317.
1998
Scholarly publications
Suriyasathaporn, W., Nielen, M., Dieleman, S. J., Brand, A., Noordhuizen-Stassen, E. N., & Schukken, Y. H. (1998). A Cox proportional-hazards model with time-dependent covariates to evaluate the relationship between body-condition score and the risks of first insemination and pregnancy in a high-producing dairy herd. Preventive Veterinary Medicine, 37(1-4), 159-172. https://doi.org/10.1016/S0167-5877(98)00100-7
Van Schaik, G., Dijkhuizen, A. A., Huirne, R. B. M., Schukken, Y. H., Nielen, M., & Hage, H. J. (1998). Risk factors for existence of Bovine Herpes Virus 1 antibodies on nonvaccinating Dutch dairy farms. Preventive Veterinary Medicine, 34(2-3), 125-136. https://doi.org/10.1016/S0167-5877(97)00085-8
1995
Scholarly publications
Nielen, M., Spigt, M. H., Schukken, Y. H., Deluyker, H. A., Maatje, K., & Brand, A. (1995). Application of a neural network to analyse on-line milking parlour data for the detection of clinical mastitis in dairy cows. Preventive Veterinary Medicine, 22(1-2), 15-28. https://doi.org/10.1016/0167-5877(94)00405-8
Schukken, Y. H., Lam, T. J., Nielen, M., Hogeveen, H., Barkema, H. W., & Grommers, F. J. (1995). Subklinische en klinische mastitis op melkvee-bedrijven in Nederland: epidemiologische ontwikkelingen. Tijdschrift voor Diergeneeskunde, 120(7), 208-13.
Nielen, M., Schukken, Y. H., Brand, A., Deluyker, H. A., & Maatje, K. (1995). Detection of subclinical mastitis from on-line milking parlor data. Journal of Dairy Science, 78(5), 1039-49. https://doi.org/10.3168/jds.S0022-0302(95)76720-0
Nielen, M., Schukken, Y. H., Brand, A., Haring, S., & Ferwerda-van Zonneveld, R. T. (1995). Comparison of analysis techniques for on-line detection of clinical mastitis. Journal of Dairy Science, 78(5), 1050-61. https://doi.org/10.3168/jds.S0022-0302(95)76721-2
van der Poel, W. H., Mourits, M. C., Nielen, M., Frankena, K., Van Oirschot, J. T., & Schukken, Y. H. (1995). Bovine respiratory syncytial virus reinfections and decreased milk yield in dairy cattle. The Veterinary quarterly, 17(3), 77-81. https://doi.org/10.1080/01652176.1995.9694537
1994
Scholarly publications
Nielen, M., Aarts, M. G., Jonkers, A. G., Wensing, T., & Schukken, Y. H. (1994). Evaluation of two cowside tests for the detection of subclinical ketosis in dairy cows. Canadian Veterinary Journal, 35(4), 229-32. https://pubmed.ncbi.nlm.nih.gov/8076278/
Nielen, M., Schukken, Y. H., & Hogeveen, H. (1994). Development of an on-line mastitis detection system within an integrated knowledge-based system for dairy farm management support. Veterinary Research, 25(2-3), 285-9.
Lansbergen, L. M., Nielen, M., Lam, T. J., Pengov, A., Schukken, Y. H., & Maatje, K. (1994). Evaluation of a prototype on-line electrical conductivity system for detection of subclinical mastitis. Journal of Dairy Science, 77(4), 1132-40. https://doi.org/10.3168/jds.S0022-0302(94)77049-1
1993
Scholarly publications
Nielen, M., Schukken, Y. H., Van de Broek, J., Brand, A., Deluyker, H. A., & Maatje, K. (1993). Relations between on-line electrical conductivity and daily milk production on a low somatic cell count farm. Journal of Dairy Science, 76(9), 2589-96. https://doi.org/10.3168/jds.S0022-0302(93)77593-1
1992
Scholarly publications
Beerepoot, G. M., Dykhuizen, A. A., Nielen, Y., & Schukken, Y. H. (1992). The economics of naturally occurring twinning in dairy cattle. Journal of Dairy Science, 75(4), 1044-51. https://doi.org/10.3168/jds.s0022-0302(92)77848-5
Nielen, M., Deluyker, H., Schukken, Y. H., & Brand, A. (1992). Electrical conductivity of milk: measurement, modifiers, and meta analysis of mastitis detection performance. Journal of Dairy Science, 75(2), 606-14. https://doi.org/10.3168/jds.S0022-0302(92)77798-4
1989
Scholarly publications
Nielen, M., Schukken, Y. H., Scholl, D. T., Wilbrink, H. J., & Brand, A. (1989). Twinning in dairy cattle: A study of risk factors and effects. Theriogenology, 32(5), 845-62. https://doi.org/10.1016/0093-691x(89)90473-1