Key recent references

1. Krijgsveld J, et al. (2003) Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics.  Nat Biotechnol 21:927-931.

2. Heck AJ (2008) Native mass spectrometry: a bridge between interactomics and structural biology.  Nature Methods 5:927-933.

3. Van Hoof D, et al. (2009) Phosphorylation dynamics during early differentiation of human embryonic stem cells.  Cell Stem Cell 5:214-226.

4. Uetrecht C, Barbu IM, Shoemaker GK, van Duijn E, & Heck AJ (2011) Interrogating viral capsid assembly with ion mobility-mass spectrometry.  Nature Chem 3:126-132.

5. de Lau W, et al. (2011) Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.  Nature 476:293-297.

6. Li VS, et al. (2012) Wnt Signaling through Inhibition of beta-Catenin Degradation in an Intact Axin1 Complex.  Cell 149:1245-1256.

7. Koo BK, et al. (2012) Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.  Nature 488:665-669.

8. Rose RJ, Damoc E, Denisov E, Makarov A, & Heck AJ (2012) High-sensitivity Orbitrap mass analysis of intact macromolecular assemblies.  Nature Methods 9:1084-1086.

9. Peng M, et al. (2012) Protease bias in absolute protein quantitation.  Nature Methods 9:524-525.

10. Ringrose JH, et al. (2013) Deep proteome profiling of Trichoplax adhaerens reveals remarkable features at the origin of metazoan multicellularity.  Nature Commun 4:1408.

11. Altelaar AF, Munoz J, & Heck AJ (2013) Next-generation proteomics: towards an integrative view of proteome dynamics.  Nature Rev Genet 14:35-48.

12. Pijnappel WW, et al. (2013) A central role for TFIID in the pluripotent transcription circuitry.  Nature 495:516-519.