Publicaties
2022
Wetenschappelijke publicaties
Asimaki, K., Vazakidou, P., van Tol, H. T. A., Oei, C. H. Y., Modder, E. A., van Duursen, M. B. M., & Gadella, B. M. (2022). Bovine
In Vitro Oocyte Maturation and Embryo Production Used as a Model for Testing Endocrine Disrupting Chemicals Eliciting Female Reproductive Toxicity With Diethylstilbestrol as a Showcase Compound. Frontiers in toxicology, 4, 811285. https://doi.org/10.3389/ftox.2022.811285
Aardema, H., Bertijn, I., van Tol, HTA., Rijneveld, A., Vernooij, JCM., Gadella, B. M., & Vos, PLAM. (2022). Fatty Acid Supplementation During in vitro Embryo Production Determines Cryosurvival Characteristics of Bovine Blastocysts. Frontiers in Cell and Developmental Biology, 10, 1-14. [837405]. https://doi.org/10.3389/fcell.2022.837405
Pavani, K. C., Meese, T., Pascottini, O. B., Guan, X., Lin, X., Peelman, L., Hamacher, J., Van Nieuwerburgh, F., Deforce, D., Boel, A., Heindryckx, B., Tilleman, K., Van Soom, A., Gadella, B. M., Hendrix, A., & Smits, K. (2022). Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts. Proceedings of the National Academy of Sciences of the United States of America, 119(12), 1-12. [e2122708119]. https://doi.org/10.1073/pnas.2122708119
Zhang, M., Chiozzi, R. Z., Skerrett-Byrne, D. A., Veenendaal, T., University, U. M. C. U., Heck, A. J. R., Nixon, B., Helms, J. B., Gadella, B. M., & Bromfield, E. G. (2022). High Resolution Proteomic Analysis of Subcellular Fractionated Boar Spermatozoa Provides Comprehensive Insights Into Perinuclear Theca-Residing Proteins. Frontiers in Cell and Developmental Biology, 10, 1-18. [836208]. https://doi.org/10.3389/fcell.2022.836208
2021
Wetenschappelijke publicaties
Leung, M. R., Chiozzi, R. Z., Roelofs, M. C., Hevler, J. F., Ravi, R. T., Maitan, P., Zhang, M., Henning, H., Bromfield, E. G., Howes, S. C., Gadella, B. M., Heck, A. J. R., & Zeev-Ben-Mordehai, T. (2021). In-cell structures of a conserved supramolecular array at the mitochondria-cytoskeleton interface in mammalian sperm. (pp. 1-17). bioRxiv. https://doi.org/10.1101/2021.02.16.431372
Leemans, B., Bromfield, E. G., Stout, T. A. E., Vos, M., Van Der Ham, H., Van Beek, R., Van Soom, A., Gadella, B. M., & Henning, H. (2021). Developing a reproducible protocol for culturing functional confluent monolayers of differentiated equine oviduct epithelial cells. Biology of Reproduction. https://doi.org/10.1093/biolre/ioab243
Leung, M. R., Ravi, R. T., Gadella, B. M., & Zeev-Ben-Mordehai, T. (2021). Membrane Remodeling and Matrix Dispersal Intermediates During Mammalian Acrosomal Exocytosis. Frontiers in Cell and Developmental Biology, 9, 1-13. [765673]. https://doi.org/10.3389/fcell.2021.765673
Maitan, P. P., Bromfield, E. G., Hoogendijk, R., Leung, M. R., Zeev-Ben-Mordehai, T., van de Lest, C. H., Jansen, J. W. A., Leemans, B., Guimarães, J. D., Stout, T. A. E., Gadella, B. M., & Henning, H. (2021). Bicarbonate-Stimulated Membrane Reorganization in Stallion Spermatozoa. Frontiers in Cell and Developmental Biology, 9, 1-17. [772254]. https://doi.org/10.3389/fcell.2021.772254
Leung, M. R., Zenezini Chiozzi, R., Roelofs, M. C., Hevler, J. F., Ravi, R. T., Maitan, P., Zhang, M., Henning, H., Bromfield, E. G., Howes, S. C., Gadella, B. M., Heck, A. J. R., & Zeev-Ben-Mordehai, T. (2021). In-cell structures of conserved supramolecular protein arrays at the mitochondria-cytoskeleton interface in mammalian sperm. Proceedings of the National Academy of Sciences of the United States of America, 118(45), 1-10. [e2110996118]. https://doi.org/10.1073/pnas.2110996118
Maitan, P., Bromfield, E. G., Stout, T. A. E., Gadella, B. M., & Leemans, B. (2021). A stallion spermatozoon's journey through the mare's genital tract: In vivo and in vitro aspects of sperm capacitation. Animal Reproduction Science, [106848]. https://doi.org/10.1016/j.anireprosci.2021.106848
Zhang, M., Bromfield, E. G., Veenendaal, T., Klumperman, J., Helms, J. B., & Gadella, B. M. (2021). Characterization of different oligomeric forms of CRISP2 in the perinuclear theca versus the fibrous tail structures of boar spermatozoa. Biology of Reproduction, 105(5), 1160-1170. https://doi.org/10.1093/biolre/ioab145
Bernecic, N. C., Graaf, S. P., Leahy, T., & Gadella, B. M. (2021). HDL mediates reverse cholesterol transport from ram spermatozoa and induces hyperactivated motility. Biology of Reproduction, 104(6), 1271-1281. https://doi.org/10.1093/biolre/ioab035
Sheng, J., Gadella, B. M., Olrichs, N. K., Kaloyanova, D. V., & Helms, J. B. (2021). The less conserved metal-binding site in human CRISP1 remains sensitive to zinc ions to permit protein oligomerization. Scientific Reports, 11(1), [5498]. https://doi.org/10.1038/s41598-021-84926-y
Wang, T-E., Minabe, S., Matsuda, F., Li, S-H., Tsukamura, H., Maeda, K-I., Smith, L., O'Hara, L., Gadella, B. M., & Tsai, P-S. (2021). Testosterone regulation on quiescin sulfhydryl oxidase 2 synthesis in the epididymis. Reproduction, 161(5), 593-602. https://doi.org/10.1530/rep-20-0629
Leung, M. R., Roelofs, M. C., Ravi, R. T., Maitan, P., Henning, H., Zhang, M., Bromfield, E. G., Howes, S. C., Gadella, B. M., Bloomfield-Gadêlha, H., & Zeev-Ben-Mordehai, T. (2021). The multi-scale architecture of mammalian sperm flagella and implications for ciliary motility. EMBO Journal, 40(7), 1-17. [e107410]. https://doi.org/10.15252/embj.2020107410
2020
Wetenschappelijke publicaties
Zhang, M., Zenezini-Chiozzi, R., Kaloyanova, D. V., Helms, J. B., & Gadella, B. M. (2020). Characterization of CRISP2 in ejaculated boar sperm and its involvement in oligomerization protein complex formation. Animal Reproduction Science, 220, [106416]. https://doi.org/10.1016/j.anireprosci.2020.106416
Gadella, B. M. (2020). Male Infertility: Shining a Light on Lipids and Lipid-Modulating Enzymes in the Male Germline. Journal of Clinical Medicine, 9(2), 327. [31979378 ]. https://doi.org/10.3390/jcm9020327
Gadella, B. M. (2020). Quantitative Proteomic Analysis of Seminal Plasma, Sperm Membrane Proteins, and Seminal Extracellular Vesicles Suggests Vesicular Mechanisms Aid in the Removal and Addition of Proteins to the Ram Sperm Membrane. Proteomics, 20(12), [e1900289]. https://doi.org/10.1002/pmic.201900289
Gadella, B. M. (2020). Synergism between albumin, bicarbonate and cAMP upregulation for cholesterol efflux from ram sperm. Reproduction, 160(2), 269-280. https://doi.org/10.1530/REP-19-0430
van Duursen, M. B. M., Boberg, J., Christiansen, S., Connolly, L., Damdimopoulou, P., Filis, P., Fowler, P. A., Gadella, B. M., Holte, J., Jääger, K., Johansson, H. K. L., Li, T., Mazaud-Guittot, S., Parent, A. S., Salumets, A., Soto, A. M., Svingen, T., Velthut-Meikas, A., Wedebye, E. B., ... van den Berg, M. (2020). Safeguarding female reproductive health against endocrine disrupting chemicals—The FREIA project. International Journal of Molecular Sciences, 21(9), [3215]. https://doi.org/10.3390/ijms21093215
Sheng, J., Olrichs, N. K., Gadella, B. M., Kaloyanova, D. V., & Helms, J. B. (2020). Regulation of Functional Protein Aggregation by Multiple Factors: Implications for the Amyloidogenic Behavior of the CAP Superfamily Proteins. International Journal of Molecular Sciences, 21(18), [6530]. https://doi.org/10.3390/ijms21186530
2019
Wetenschappelijke publicaties
Gadella, B. M., Bromfield, E., Walter, JLH., Cafe, SL., Bernstein, IR., Anderson, AL., Aitken, R. J., McLaughlin, EA., Dunn, M., & Nixon, B. (2019). Differential cell death decisions in the testis: evidence for an exclusive window of ferroptosis in round spermatids. Molecular Human Reproduction, 25(5), 241-256. https://doi.org/10.1093/molehr/gaz015
Leemans, B., Stout, T. A. E., Van Soom, A., & Gadella, B. M. (2019). pH dependent effects of procaine on equine gamete activation. Biology of Reproduction, 101(5), 1056-1074. https://doi.org/10.1093/biolre/ioz131
Bernecic, N. C., Gadella, B. M., Leahy, T., & de Graaf, S. P. (2019). Novel methods to detect capacitation-related changes in spermatozoa. Theriogenology, 137, 56-66. https://doi.org/10.1016/j.theriogenology.2019.05.038
Bernecic, N. C., Zhang, M., Gadella, B. M., Brouwers, J. F. H. M., Jansen, J. W. A., Arkesteijn, G. J. A., de Graaf, S. P., & Leahy, T. (2019). BODIPY-cholesterol can be reliably used to monitor cholesterol efflux from capacitating mammalian spermatozoa. Scientific Reports, 9(1), [9804]. https://doi.org/10.1038/s41598-019-45831-7
Leemans, B., Stout, T. A. E., De Schauwer, C., Heras, S., Nelis, H., Hoogewijs, M., Van Soom, A., & Gadella, B. M. (2019). Update on mammalian sperm capacitation: How much does the horse differ from other species? Reproduction, 157(5), R181-R197. https://doi.org/10.1530/REP-18-0541
Sheng, J., Olrichs, N. K., Geerts, W. J., Li, X., Rehman, A. U., Gadella, B. M., Kaloyanova, D. V., & Helms, J. B. (2019). Zinc binding regulates amyloid-like aggregation of GAPR-1. Bioscience Reports, 39(2). https://doi.org/10.1042/BSR20182345
2018
Wetenschappelijke publicaties
Aardema, H., Vos, P. L. A. M., & Gadella, B. M. (2018). Cumulus cells protect the oocyte against saturated free fatty acids. Animal Reproduction, 15(Supplement 1), 737-750. https://doi.org/10.21451/1984-3143-AR2018-0063
Ferraz, M. A. M. M., Rho, H. S., Hemerich, D., Henning, H. H. W., van Tol, H. T. A., Hölker, M., Besenfelder, U., Mokry, M., Vos, P. L. A. M., Stout, T. A. E., Le Gac, S., & Gadella, B. M. (2018). An oviduct-on-a-chip provides an enhanced in vitro environment for zygote genome reprogramming. Nature Communications, 9(1), [4934]. https://doi.org/10.1038/s41467-018-07119-8
Pini, T., de Graaf, S. P., Druart, X., Tsikis, G., Labas, V., Teixeira-Gomes, A. P., Gadella, B. M., & Leahy, T. (2018). Binder of Sperm Proteins 1 and 5 have contrasting effects on the capacitation of ram spermatozoa. Biology of Reproduction, 98(6), 765-775. https://doi.org/10.1093/biolre/ioy032
de Almeida Monteiro Melo Ferraz, M., Henning, H. H. W., Ferreira da Costa, P., Malda, J., Le Gac, S., Bray, F., van Duursen, M. B. M., Brouwers, J. F., van de Lest, C. H. A., Bertijn, I., Kraneburg, L., Vos, P. L. A. M., Stout, T. A. E., & Gadella, B. M. (2018). Potential Health and Environmental Risks of Three-Dimensional Engineered Polymers. Environmental science & technology letters, 5(2), 80-85. https://doi.org/10.1021/acs.estlett.7b00495
2017
Wetenschappelijke publicaties
Ferraz, M., Rho, H. S., Delahaye, J., Pinheiro, N., Henning, H., Stout, T., Gadella, B., & Le Gac, S. (2017). Mimicking the bovine oviduct in a microfluidic device for advanced embryo in vitro culture systems. In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 (pp. 1047-1048). (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017). Chemical and Biological Microsystems Society. https://www.mendeley.com/catalogue/614dc323-1493-3be8-b2da-47f88f48b15a/
Gadella, B. M. (2017). Reproductive tract modifications of the boar sperm surface. Molecular Reproduction and Development, 84(9), 822-831. https://doi.org/10.1002/mrd.22821
Aardema, H., van Tol, H. T. A., Wubbolts, R. W., Brouwers, J. F. H. M., Gadella, B. M., & Roelen, B. A. J. (2017). Stearoyl-CoA desaturase activity in bovine cumulus cells protects the oocyte against saturated fatty acid stress. Biology of Reproduction, 96(5), 982-992. https://doi.org/10.1095/biolreprod.116.146159
de Almeida Monteiro Melo Ferraz, M., Henning, H. H. W., Ferreira da Costa, P., Malda, J., Melchels, F. P. W., Wubbolts, R. W., Stout, T. A. E., Vos, P. L. A. M., & Gadella, B. M. (2017). Improved bovine embryo production in an oviduct-on-a-chip system: prevention of poly-spermic fertilization and parthenogenic activation. Lab on a Chip - Miniaturisation for Chemistry and Biology, 17(5), 905-916. https://doi.org/10.1039/c6lc01566b
de Almeida Monteiro Melo Ferraz, M., Henning, H. H. W., Stout, T. A. E., Vos, P. L. A. M., & Gadella, B. M. (2017). Designing 3-Dimensional In Vitro Oviduct Culture Systems to Study Mammalian Fertilization and Embryo Production. Annals of Biomedical Engineering, 45(7), 1731-1744. https://doi.org/10.1007/s10439-016-1760-x
Brewis, I. A., & Gadella, B. M. (2017). Sperm Surface Proteomics 2. In W. K. H. Krauze, & R. K. Naz (Eds.), Immune infertility 2nd edition (2 ed., pp. 49-76). Springer. https://doi.org/10.1007/978-3-319-40788-3_3
2016
Wetenschappelijke publicaties
Leemans, B., Gadella, B. M., Stout, T. A. E., De Schauwer, C., Nelis, H., Hoogewijs, M., & Van Soom, A. (2016). The Role of Oviductal Cells in Activating Stallion Spermatozoa. Journal of Equine Veterinary Science, 43(Supplement), S49-S55. https://doi.org/10.1016/j.jevs.2016.06.003
Gadella, B. M., & Boerke, A. (2016). An update on post-ejaculatory remodeling of the sperm surface before mammalian fertilization. Theriogenology, 85(1), 113-124. https://doi.org/10.1016/j.theriogenology.2015.07.018
Ferraz, M. A. M. M., Henning, H. H. W., Stout, T. A. E., Vos, P. L. A. M., & Gadella, B. M. (2016). Erratum to: Designing 3-Dimensional In Vitro Oviduct Culture Systems to Study Mammalian Fertilization and Embryo Production. Annals of Biomedical Engineering. https://doi.org/10.1007/s10439-016-1767-3
Davila, M. P., Muñoz, P. M., Bolaños, J. M. G., Stout, T. A. E., Gadella, B. M., Tapia, J. A., da Silva, C. B., Ferrusola, C. O., & Peña, F. J. (2016). Mitochondrial ATP is required for the maintenance of membrane integrity in stallion spermatozoa, whereas motility requires both glycolysis and oxidative phosphorylation. Reproduction, 152(6), 683-694. https://doi.org/10.1530/REP-16-0409
Leemans, B., Gadella, B. M., Stout, T. A. E., De Schauwer, C., Nelis, H. M., Hoogewijs, M., & Van Soom, A. (2016). Why doesn't conventional IVF work in the horse? Reproduction, 152, 233-245. https://doi.org/10.1530/REP-16-0420
Kuo, Y-W., Li, S-H., Maeda, K-I., Gadella, B., & Tsai, P-S. J. (2016). Roles of the reproductive tract in modifications of the sperm membrane surface. Journal of Reproduction and Development, 62(4), 337-343. https://doi.org/10.1262/jrd.2016-028
Kuo, Y. W., Liu, H. T., Li, S. H., Maeda, K. I., Gadella, B., & Tsai, P. S. J. (2016). The involvement of epididymal secretory proteins in the selection processes of sperm cells. Molecular Reproduction and Development, 83(3), 187. https://doi.org/10.1002/mrd.22622
Leemans, B., Gadella, B. M., Stout, T. A. E., Sostaric, E., De Schauwer, C., Nelis, H. M., Hoogewijs, M., & Van Soom, A. (2016). Combined albumin and bicarbonate adversely affects equine sperm-oviduct binding. Reproduction, 151, 313-330. https://doi.org/10.1530/REP-15-0471
2015
Wetenschappelijke publicaties
Brogan, P. T., Beitsma, M., Henning, H., Gadella, B. M., & Stout, T. A. E. (2015). Liquid storage of equine semen: Assessing the effect of D-penicillamine on longevity of ejaculated and epididymal stallion sperm. Animal Reproduction Science, 159, 155-162. https://doi.org/10.1016/j.anireprosci.2015.06.011
Ferraz, M. A. M. M., Henning, H. H. W., Vos, P. L. A. M., Stout, T. A. E., & Gadella, B. M. (2015). A novel 3-D culture system to study bovine oviduct physiology, gamete interaction and early embryo development. Proceedings of the 31st Meeting of the European Embryo Transfer Association (AETE); Ghent, Belgium, 1. http://www.mendeley.com/research/novel-3d-culture-system-study-bovine-oviduct-physiology-gamete-interaction-early-embryo-development
Gadella, B. M., & Ferraz, M. A. (2015). A Review of New Technologies that may Become Useful for in vitro Production of Boar Sperm. Reproduction in Domestic Animals, 50, 61-70. https://doi.org/10.1111/rda.12571
Vos, P. L. A. M., van der Weijden, G. C., Gadella, B. M., & Taverne, M. A. M. (2015). Obituary: Dr. Steph J. Dieleman. Theriogenology, 84(3), 321-322. [PMID: 26247073 ]. https://doi.org/10.1016/j.theriogenology.2015.04.003
van Gestel, R. A., Brouwers, J. F., Ultee, A., Helms, J. B., & Gadella, B. M. (2015). Ultrastructure and lipid composition of detergent-resistant membranes derived from mammalian sperm and two types of epithelial cells. Cell and Tissue Research, 363(1), 129-145. https://doi.org/10.1007/s00441-015-2272-y
Leemans, B., Gadella, B. M., Stout, T. A. E., Nelis, H., Hoogewijs, M., & Van Soom, A. (2015). An alkaline follicular fluid fraction induces capacitation and limited release of oviduct epithelium-bound stallion sperm. Reproduction, 150(3), 193-208. https://doi.org/10.1530/REP-15-0178
Leemans, B., Gadella, B. M., Stout, T. A. E., Heras, S., Smits, K., Ferrer-Buitrago, M., Claes, E., Heindryckx, B., De Vos, W. H., Nelis, H., Hoogewijs, M., & Van Soom, A. (2015). Procaine Induces Cytokinesis in Horse Oocytes via a pH Dependent Mechanism. Biology of Reproduction. https://doi.org/10.1095/biolreprod.114.127423
Leahy, T., & Gadella, B. M. (2015). New insights into the regulation of cholesterol efflux from the sperm membrane. Asian Journal of Andrology. https://doi.org/10.4103/1008-682X.153309
Aardema, H., Gadella, B. M., van de Lest, C. H. A., Brouwers, J. F. H. M., Stout, T. A. E., Roelen, B. A. J., & Vos, P. L. A. M. (2015). Free fatty acid levels in fluid of dominant follicles at the preferred insemination time in dairy cows are not affected by early postpartum fatty acid stress. Journal of Dairy Science, 98(4), 2322-2336. https://doi.org/10.3168/jds.2014-7970
Lolicato, F., Brouwers, J. F., van de Lest, C. H. A., Wubbolts, R., Aardema, H., Priore, P., Roelen, B. A. J., Helms, J. B., & Gadella, B. M. (2015). The Cumulus Cell Layer Protects Bovine Maturing Oocyte Against Fatty Acid-Induced Lipotoxicity. Biology of Reproduction, 92(1), [16]. https://doi.org/10.1095/biolreprod.114.120634
Vakpublicaties
Bijleveld, C., Geelen, M. J. H., van Haeften, T., van der Woude, J. W., Tielens, A. G. M., van Dongen, A. M., van der Leij, W. J. R., Piek, C. J., Prins, M., Teske, E., J.P.H.M., V., Gadella, B. M., Lam, T. J. G. M., Rijneveld, A., Roelen, B. A. J., Beitsma, M. M., Egberink, H. F., van Dijk, M. A. M., Duijvestijn, M. B. H. M., ... Heuvelink, A. E. (2015). Laboratoriumdiagnostiek: een praktische handleiding. In J. de Kool-van der Woude (Ed.), laboratoriumdiagnostiek: een praktische handleiding [ISBN 978-90-393-6776-6] Ponsen & Looijen.
2014
Wetenschappelijke publicaties
Boerke, A., van der Lit, J., Lolicato, F., Stout, T. A. E., Helms, J. B., & Gadella, B. M. (2014). Removal of GPI-anchored membrane proteins causes clustering of lipid microdomains in the apical head area of porcine sperm. Theriogenology, 81(4), 613-624. https://doi.org/10.1016/j.theriogenology.2013.11.014
Gadella, B. M. (2014). Sperm preparation for fertilization. In P. J. Chenoweth (Ed.), Animal Andrology, theories and applications, part I (pp. 57-75). CAB international. https://doi.org/10.1079/9781780643168.0000
Leemans, B., Gadella, B. M., Sostaric, E., Nelis, H., Stout, T. A. E., Hoogewijs, M., & van Soom, A. (2014). Oviduct Binding and Elevated Environmental pH Induce Protein Tyrosine Phosphorylation in Stallion Spermatozoa. Biology of Reproduction, 91(1), 1-12. [13]. https://doi.org/10.1095/biolreprod.113.116418
Gadella, B. M., & Luna, C. (2014). Cell biology and functional dynamics of the mammalian sperm surface. Theriogenology, 81(1), 74-84. https://doi.org/10.1016/j.theriogenology.2013.09.005
Overige resultaten
Brogan, P., Beitsma, M., Henning, H., Stout, T., & Gadella, B. (2014). Developing a dynamic test to identify stallions with reduced sperm DNA stability. Journal of Equine Veterinary Science, 34(1), 64.
2013
Wetenschappelijke publicaties
Aardema, H., Lolicato, F., Roelen, B. A. J., Vos, P. L. A. M., Helms, J. B., & Gadella, B. M. (2013). Cumulus cells protect oocytes against potential lipotoxicity from elevated free fatty acid concentrations in follicular fluid. Reproduction Fertility and Development, 25(1), 148-148. https://doi.org/10.1071/RDv25n1Ab1
Aardema, H., Roelen, B. A. J., van Tol, H. T. A., Oei, C. H. Y., Gadella, B. M., & Vos, P. L. A. M. (2013). Follicular 17β-estradiol and progesterone concentrations and degree of cumulus cell expansion as predictors of in vivo-matured oocyte developmental competence in superstimulated heifers. Theriogenology, 80(6), 576-83. https://doi.org/10.1016/j.theriogenology.2013.05.025
Gadella, B. M. (2013). Dynamic regulation of sperm interactions with the zona pellucida prior to and after fertilisation. Reproduction Fertility and Development, 25(1), 26-37. https://doi.org/10.1071/RD12277
Boerke, A., Brouwers, J. F., Olkkonen, V. M., van de Lest, C. H. A., Sostaric, E., Schoevers, E. J., Helms, J. B., & Gadella, B. M. (2013). Involvement of Bicarbonate-Induced Radical Signaling in Oxysterol Formation and Sterol Depletion of Capacitating Mammalian Sperm During In Vitro Fertilization. Biology of Reproduction, 88(1), 1-18. [21]. https://doi.org/10.1095/biolreprod.112.101253
Aardema, H., Lolicato, F., van de Lest, C. H. A., Brouwers, J. F., Vaandrager, A. B., van Tol, H. T. A., Roelen, B. A. J., Vos, P. L. A. M., Helms, J. B., & Gadella, B. M. (2013). Bovine cumulus cells protect maturing oocytes from increased fatty acid levels by massive intracellular lipid storage. Biology of Reproduction, 88(6), 1-15. https://doi.org/10.1095/biolreprod.112.106062
Broekhuijse, M., Šoštarić, E., Feitsma, H., & Gadella, B. M. (2013). Relationship of fl ow cytometric sperm integrity assessments with boar fertility performance under optimized fi eld conditions1. Journal of Animal Science, 90, 4327-4336. https://doi.org/10.2527/jas2012-5040
Aalberts, M., Sostaric, E., Wubbolts, R. W., Wauben, M. H. M., Nolte-'t Hoen, E. N. M., Gadella, B. M., Stout, T. A. E., & Stoorvogel, W. (2013). Spermatozoa recruit prostasomes in response to capacitation induction. Biochimica et Biophysica Acta-Proteins Proteomics, 1834((11)), 2326-2335. https://doi.org/10.1016/j.bbapap.2012.08.008
2012
Wetenschappelijke publicaties
Broekhuijse, M. L. W. J., Sostaric, E., Feitsma, H., & Gadella, B. M. (2012). Application of computer-assisted semen analysis to explain variations in pig fertility. Journal of Animal Science, 90(3), 779-789.
Broekhuijse, M. L. W. J., Sostaric, E., Feitsma, H., & Gadella, B. M. (2012). The value of microscopic semen motility assessment at collection for a commercial artificial insemination center, a retrospective study on factors explaining variation in pig fertility. Theriogenology, 77, 1466-1479. https://doi.org/10.1016/j.theriogenology.2011.11.016
Broekhuijse, M. L. W. J., Feitsma, H., & Gadella, B. M. (2012). Artificial insemination in pigs: predicting male fertility. Veterinary Quarterly, 32(3-4 September - December 2012), 151-157. https://doi.org/10.1080/01652176.2012.735126
Tsai, P. S., Brewis, I. A., van Maaren, J., & Gadella, B. M. (2012). Involvement of Complexin 2 in Docking, Locking and Unlocking of Different SNARE Complexes during Sperm Capacitation and Induced Acrosomal Exocytosis. PLoS One, 7(3), 10.1371/journal.pone.0032603. [e32603]. https://doi.org/10.1371/journal.pone.0032603
2011
Wetenschappelijke publicaties
Aardema, H., Roelen, B. A. J., Gadella, B. M., & Vos, P. L. A. M. (2011). Metabolic stress impairs follicular growth in superovulated heifers. Reproduction Fertility and Development, 23(1), 189-189. https://doi.org/10.1071/RDv23n1Ab175
Gadella, B. M. (2011). Interaction of sperm with the Zona Pellucida during fertilization. In TE. Spencer, MF. Smith, & MC. Lucy (Eds.), Reproduction in Domestic Animals VIII (pp. 267-287). (Soc Reprod Fert Suppl; No. 67). Notting University Press.
Brouwers, J. F. H. M., Boerke, A., da Silva, P. F. N., Garcia-Gil, N., van Gestel, R. A., Helms, J. B., van de Lest, C. H. A., & Gadella, B. M. (2011). Mass Spectrometric detection of cholestrol oxidation in bovine sperm. Biology of Reproduction, 85, 128-136.
Tsai, P. S., van Haeften, T., & Gadella, B. M. (2011). Preparation of the Cortical Reaction: Maturation-Dependent Migration of SNARE proteins, Clathrin, and Complexin to the Porcine oocyte's surface blocks membrane traffic until fertilization. Biology of Reproduction, 84, 327-335.
Aardema, H., Vos, P. L. A. M., Lolicato, F., Roelen, B. A. J., Knijn, H. M., Vaandrager, A. B., Helms, J. B., & Gadella, B. M. (2011). Oleic Acid Prevents Detrimental Effects of Saturated Fatty Acids on Bovine Oocyte. Biology of Reproduction, 85(1), 62-69.
Leahy, T., & Gadella, B. M. (2011). Sperm surface changes and physiological consequences induced by sperm handling and storage. Reproduction, Dec 142((6)), 759-778.
Leahy, T., & Gadella, B. M. (2011). Capacitation and Capacitation-like sperm surface changes induced by handling boar semen. Reproduction in Domestic Animals, 46(Suppl.2), 7-13.
Feitsma, H., Broekhuijse, M., & Gadella, B. M. (2011). Do CASA systems satisfy consumers demands? A critical analysis. Reproduction in Domestic Animals, 46(suppl.2), 49-51.
Filannino, A., Stout, T. A. E., Gadella, B. M., Sostaric, E., Pizzi, F., Colenbrander, B., Dell'Aquila, M. E., & Minervini, F. (2011). Dose-response effects of estrogenic mycotoxins (zearalenone, alpha- and beta-zearalenol) on motility, hyperactivation and the acrosome reaction of stallion sperm. Reproductive Biology and Endocrinology [E], 9, 134-144.
https://dspace.library.uu.nl/bitstream/handle/1874/229599/Dose-response.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/229599/Dose-response.pdf?sequence=1
Gadella, B. M., & Evans, J. P. (2011). Membrane Fusions During Mammalian Fertilization. Advances in Experimental Medicine and Biology, 713, 65-80.
https://dspace.library.uu.nl/bitstream/handle/1874/235549/2011_55.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/235549/2011_55.pdf?sequence=1
Broekhuijse, M., Feitsma, H., & Gadella, B. M. (2011). Field data analysis of boar semen quality. Reproduction in Domestic Animals, 46(suppl.2), 59-63.
Broekhuijse, M. L. W. J., Sostaric, E., Feitsma, H., & Gadella, B. M. (2011). Additional value of computer assisted semen analysis (CASA) compared to conventional motility assessments in pig artificial insemination. Theriogenology, 76, 1473-1486.
2010
Wetenschappelijke publicaties
Aardema, H., Vos, P., Knijn, H., Roelen, B., & Gadella, B. (2010). Unsaturated and saturated non-esterified fatty acids differently affect lipid storage and developmental competence of bovine oocytes. Reproduction Fertility and Development, 22(1), 319-320. https://doi.org/10.1071/RDv22n1Ab327
Tsai, P. S., Garcia-Gil, N., van Haeften, T., & Gadella, B. M. (2010). How pig sperm prepares to fertilize: stable acrosome docking to the plasma membrane. PLoS One, 5(6), e11204.
https://dspace.library.uu.nl/bitstream/handle/1874/202963/How%2520pig%2520sperm%2520prepares%2520to%2520fertilize%2520stable%2520acrosome%2520docking%2520to%2520the%2520plasma%2520membrane.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/202963/How%2520pig%2520sperm%2520prepares%2520to%2520fertilize%2520stable%2520acrosome%2520docking%2520to%2520the%2520plasma%2520membrane.pdf?sequence=1
Brewis, I. A., & Gadella, B. M. (2010). Sperm surface proteomics: from protein lists to biological function. Molecular Human Reproduction, 16(2), 68-79.
Tsai, P. S., van Haeften, T., & Gadella, B. M. (2010). Preparation of the cortical reaction: Maturation-dependent migration of SNARE proteins, clathrin and complesin to the porcine oocyte surface blocks membrane traffic until fertilization. Biology of Reproduction, 84, 327-335.
Vakpublicaties
Gadella, B. M., & van Gestel, R. A. (2010). Hv1-protonpompen en de activering van spermacellen. Folia Pharmaceutica, 4(4), 10-13.
https://dspace.library.uu.nl/bitstream/handle/1874/204427/Hv1-protonpompen%2520en%2520de%2520activering%2520van%2520spermacellen.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/204427/Hv1-protonpompen%2520en%2520de%2520activering%2520van%2520spermacellen.pdf?sequence=1
2009
Wetenschappelijke publicaties
Aardema, H., Vos, P. L. A. M., Roelen, B. A. J., Knijn, H. M., & Gadella, B. M. (2009). Developmental competence and lipid droplet features of maturing bovine oocytes are affected by saturated and not by unsaturated fatty acids. Reproduction in Domestic Animals, 44, 81-81.
Gadella, B. M. (2009). Sperm Surface Proteomics. In W. K. H. Krause, & R. K. Naz (Eds.), Immune Infertility: The impact of immune reactions on human infertility (pp. 33-48). Springer.
Santos, R. R., Knijn, H. M., Vos, P. L. A. M., Oei, C. H. Y., van Loon, T., Colenbrander, B., Gadella, B. M., van den Hurk, R., & Roelen, B. A. J. (2009). Complete follicular development and recovery of ovarian function of frozen-thawed, autotransplanted caprine ovarian cortex. Fertility and Sterility, 91(4 Suppl), 1455-1458. https://doi.org/10.1016/j.fertnstert.2008.07.018
https://dspace.library.uu.nl/bitstream/handle/1874/308732/2008.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/308732/2008.pdf?sequence=1
Tsai, P. S., & Gadella, B. M. (2009). Molecular kinetics of proteins at the surface of porcine sperm before and during fertilization. Society of Reproduction and Fertility supplement, 66, 23-36.
Gadella, B. M. (2009). Sperm surface proteomics. In W. K. H. Krause, & R. K. Naz (Eds.), Immune infertility (pp. 33-48). Springer.
2008
Wetenschappelijke publicaties
Aardema, H., Knijn, H. M., Oei, C. H. Y., Vos, P. L. A. M., & Gadella, B. M. (2008). Lipid Droplet Dynamics during In Vitro Maturation of Bovine Oocytes. Reproduction in Domestic Animals, 43, 76-76.
Gadella, B. M., Tsai, P. S., Boerke, A., & Brewis, I. A. (2008). Sperm head membrane reorganisation during capacitation. International Journal of Developmental Biology, 52((5-6)), 473-480.
Santos, R. R., van Haeften, T., Roelen, B. A. J., Knijn, H. M., Colenbrander, B., Gadella, B. M., & van den Hurk, R. (2008). Osmotic tolerance and freezability of isolate caprine ealy-staged follicles. Cell and Tissue Research, 333(2), 323-331.
Gadella, B. M. (2008). The assembly of a Zona Pellucida binding protein complex in sperm. Reproduction in Domestic Animals, 43, 12-19.
Boerke, A., Tsai, P. S., Garcia-Gil, N., Brewis, I. A., & Gadella, B. M. (2008). Capacitation-dependent reorganization of microdomains in the apical sperm head plasma membrane: functional relationship with zona binding and the zona-induced acrosome reaction. Theriogenology, 70(8), 1188-1196.
Peterson, K., Brinkhof, J. M. A., Houwers, D. J., Colenbrander, B., & Gadella, B. M. (2008). Presence of prolentiviral DNA in male sexual organs and ejaculates of small ruminants. Theriogenology, 69(4), 433-442.
Gadella, B. M. (2008). Sperm membrane physiology and relevance for fertilization. Animal Reproduction Science, 107, 229-236.
https://dspace.library.uu.nl/bitstream/handle/1874/32037/9.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/32037/9.pdf?sequence=1
Sostaric, E., Dieleman, S. J., van de Lest, C. H. A., Colenbrander, B., Vos, P. L. A. M., Garcia-Gil, N., & Gadella, B. M. (2008). Sperm binding properties and secretory activity of the bovine oviduct immediately before and after ovulation. Molecular Reproduction and Development, 75, 60-74.
Sostaric, E., Aalberts, M., Gadella, B. M., & Stout, T. A. E. (2008). The roles of the epididymis and prostasomes in the attainment of fertilizing capacity by stallion sperm. Animal Reproduction Science, 107(3-4), 237-248.
https://dspace.library.uu.nl/bitstream/handle/1874/32036/8.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/32036/8.pdf?sequence=1
Mizrak, S. C., Gadella, B. M., Erdost, H., Ozer, A., van Pelt, A. M. M., & van Dissel-Emiliani, F. M. F. (2008). Spermatogonial stem cell sensitivity to capsaicin: An in vitro study. Reproductive Biology and Endocrinology [E], 6, 52.
2007
Wetenschappelijke publicaties
da Silva, P. F. N., Gadella, B. M., Colenbrander, B., & Roelen, B. A. J. (2007). Exposure of bovine sperm to pro-oxidants impairs the developmental competence of the embryo after the first cleavage. Theriogenology, 67, 609-619.
Peterson, K., Kappen, M. P. A. M., Ursem, P. J. F., Colenbrander, B., & Gadella, B. M. (2007). Microscopic and flow cytometric semen assessment of Dutch AI-bucks: Effect of semen processing procedures and their correlation to fertility. Theriogenology, 67, 863-871.
Ono, N., van der Heijden, I., Scheffer, G. L., van de Wetering, K., van Deemter, E., de Haas, M., Boerke, A., Gadella, B. M., de Rooij, D. G., Neefjes, J. J., Groothuis, T. A. M., Oomen, L., Brocks, L., Ishakawa, T., & Borst, P. (2007). Multidrug resistance-associated protein 9 (ABCC12) is present in mouse and boar sperm. Biochemical Journal, 406(1), 31-40.
Tsai, P. S., de Vries, K. J., de Boer-Brouwer, M., Garcia-Gil, N., van Gestel, R. A., Colenbrander, B., Gadella, B. M., & van Haeften, T. (2007). Syntaxin and VAMP association with lipid rafts depends on cholesterol depletion in capacitating sperm cells. Molecular Membrane Biology, 24, 313-324.
Boerke, A., Dieleman, S. J., & Gadella, B. M. (2007). A possible role for sperm RNA in early embryo development. Theriogenology, 68, 147-155.
van Gestel, R. A., Brewis, I. A., Ashton, P. R., Brouwers, J. F. H. M., & Gadella, B. M. (2007). Multiple proteins present in purified porcine sperm apical plasma membranes interact with the zona pellucida of the oocyte. Molecular Human Reproduction, 13, 445-454.
https://dspace.library.uu.nl/bitstream/handle/1874/26424/42_multiple_gestel.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/26424/42_multiple_gestel.pdf?sequence=1
2006
Wetenschappelijke publicaties
Fatehi, A. N., Bevers, M. M., Schoevers, E., Roelen, B. A. J., Colenbrander, B., & Gadella, B. M. (2006). DNA damage in bovine sperm does not block fertilization and early embryonic development but induces apoptosis after the first cleavages. Journal of Andrology, 27(2), 176-188. https://doi.org/10.2164/jandrol.04152
da Silva, P. F. N., & Gadella, B. M. (2006). Detection of damage in mammalian sperm cells. Theriogenology, 65(5), 958-978.
Gadella, B. M., & Visconti, P. (2006). Regulation of capacitation. In Jonge, & Barrats (Eds.), The sperm cell: production, maturation, fertilization, regeneration Cambridge University Press.
2005
Wetenschappelijke publicaties
van Gestel, R. A., Brewis, I. A., Ashton, P. R., Helms, J. B., Brouwers, J. F. H. M., & Gadella, B. M. (2005). Capacitation-dependent concentration of lipid rafts in the apical ridge head area of porcine sperm cells. Molecular Human Reproduction, 11(8), 583-590.
Harrison, R. A. P., & Gadella, B. M. (2005). Bicarbonate-induced membrane processing in sperm capacitation. Theriogenology, 63(2), 342-351.
Brewis, I. A., van Gestel, R. A., Gadella, B. M., Jones, R., Publicover, S. J., Roldan, E. R., Frayne, J., & Barrat, C. L. (2005). The spermatozoon at fertilisation: current understanding and future research directions. Human Fertility, 4, 241-251.
van Gestel, R. A., Helms, J. B., Brouwers, J. F. H. M., & Gadella, B. M. (2005). Effects of methyl-beta-cyclodextrin-mediated cholesterol depletion in porcine sperm compared to somatic cells. Molecular Reproduction and Development, 72, 386-395.
Brewis, I. A., Moore, H. D., Fraser, L., Holt, W. V., Baldi, E., Luconi, M., Gadella, B. M., Ford, W. C., & Harrison, R. A. P. (2005). Molecular mechanisms during sperm capacitation. Human Fertility, 4, 253-261.
Brouwers, J. F. H. M., da Silva, P. F. N., & Gadella, B. M. (2005). New assays for detection and localization of endogenous lipid peroxidation products in living boar sperm after BTS dilution or after freeze-thawing. Theriogenology, 63, 458-470.
Neild, D. N., Gadella, B. M., Aguero, A., Stout, T. A. E., & Colenbrander, B. A. (2005). Capacitation, Acrosome function and Chromatin structure in Stallion sperm. Animal Reproduction Science, 89, 47-56.
https://dspace.library.uu.nl/bitstream/handle/1874/19854/Neild%2520et%2520al%25202005.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/19854/Neild%2520et%2520al%25202005.pdf?sequence=1
Johnson, L. A., & Gadella, B. M. (2005). History of the boar semen conference. Theriogenology, 63, 279-282.
Fatehi, A. N., Roelen, B. A. J., Colenbrander, B., Schoevers, E. J., Gadella, B. M., Bevers, M. M., & Van Den Hurk, R. (2005). Presence of cumulus cells during in vitro fertilization protects the bovine oocyte against oxidative stress and improves first cleavage but does not affect further development. Zygote, 13(2), 177-185. https://doi.org/10.1017/S0967199405003126
Neild, D. M., Brouwers, J. F. H. M., Colenbrander, B. A., Aguero, A., & Gadella, B. M. (2005). Lipid peroxide formation in relation to membrane stability of fresh and frozen thawed stallion spermatozoa. Molecular Reproduction and Development, 72, 230-238.
Gadella, B. M., & Colenbrander, B. A. (2005). Theriogenology. (63 ed.) Elsevier.
Sostaric, E., van de Lest, C. H. A., Colenbrander, B. A., & Gadella, B. M. (2005). Dynamics of carbohydrate affinities at the cell surface of capacitating bovine sperm cells. Biology of Reproduction, 72(2), 346-357.
2004
Wetenschappelijke publicaties
Gadella, B. M., & Colenbrander, B. A. (2004). Bicarbonate dependent capcitation of sperm from various species. In E. Squires, & J.F. Wade (Eds.), Transporting Gametes and Embryos. (pp. 43-50). (Havemeyer Foundation Monograph Series; No. 12). R&W Publications.
Nolte-'t Hoen, E. N. M., Wagenaar-Hilbers, J. P. A., Peters, P. J., Gadella, B. M., & Wauben, M. H. M. (2004). Uptake of membrane molecules from T cells endows antigen-presenting cells with novel functional properties. European Journal of Immunology, 34(11), 3115-3125.
Stout, T. A. E., Colenbrander, B. A., & Gadella, B. M. (2004). Capacitation and the acrosome reaction in stallion sperm. In M. Alvarenga, & J. F. Wade (Eds.), Havemeyer Foundation Monograph Series no. 14 (pp. 55-57).
Peterson, K., Kappen, M. J., Gadella, B. M., & Colenbrander, B. A. (2004). Evaluation de la qualite de la semence fraiche des boucs d'insemination Hollandais: criteres, methodes, conservation et fertilite. In Proc Symp Satellite Caprin 11de (pp. 25-28).
Gadella, B. M., & van Gestel, R. A. (2004). Bicarbonate and its role in mammalian sperm function. Animal Reproduction Science, 82-83, 307-319.
de Graaf, P., Zwart, W. T., van Dijken, R. A. J., Deneka, M., Schulz, T. K. F., Geijsen, N., Coffer, P. J., Gadella, B. M., Verkleij, A. J., van der Sluijs, P., & van Bergen en Henegouwen, P. M. P. (2004). Phosphatidylinositol 4-kinase beta is critical for functional association of rab11 with the Golgi complex. Molecular Biology of the Cell, 15, 2038-2047.
Schenning, M., van Tiel, C. M., van Manen, D., Stam, J. C., Gadella, B. M., Wirtz, K. W. A., & Snoek, G. T. (2004). Phosphatidylinositol transfer protein α regulates growth and apoptosis of NIH3T3 cells: involvement of a cannabinoid 1-like receptor. Journal of Lipid Research, 45(8), 1555-1564.
https://dspace.library.uu.nl/bitstream/handle/1874/14606/7.Schenning%25202004%2520pp%25201555-1564.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/14606/7.Schenning%25202004%2520pp%25201555-1564.pdf?sequence=1
Drummen, G. P. C., Gadella, B. M., Post, J. A., & Brouwers, J. F. H. M. (2004). Mass spectrometric characterization of the oxidation of the fluorescent lipid peroxidation reporter molecule C11-BODIPY(581/591). Free Radical Biology and Medicine, 36(12), 1635-1644.
2003
Wetenschappelijke publicaties
Nield, D. M., Gadella, B. M., Chaves, M. G., Miragaya, M. H., Colenbrander, B. A., & Aguero, A. (2003). Membrane changes during different stages of a freeze-thaw protocol for equine semen cryopreservation. Theriogenology, 59(Iss 8), 1693-1705.
Hendriksen, P. J. M., Gadella, B. M., Vos, P. L. A. M., Mullaart, E., Kruip, T. A. M., & Dieleman, S. J. (2003). Follicular dynamics around the recruitment of the first follicular wave in the cow. Biology of Reproduction, 69, 2036-2044.
Nagy, S., Jansen, J. A., Topper, E. K., & Gadella, B. M. (2003). A triple-stain flow cytometric method to assess plasma- and acrosome-membrane integrity of cryopreserved bovine sperm immediately after thawing in presence of egg-yolk particles. Biology of Reproduction, 68(5), 1828-1835.
de Vries, K. J., Wiedmer, T., Sims, P. J., & Gadella, B. M. (2003). Caspase independent exposure of Aminophospholipids and tyrosine phosphorylation in bicarbonate responsive human sperm cells. Biology of Reproduction, 68, 2122-2134.
da Silva, P. F. N., Brouwers, J. F. H. M., Helms, J. B., Colenbrander, B. A., & Gadella, B. M. (2003). Cholesterol oxidation is a common phenomenon in bovine sperm cells. Reproduction, 30, 87-88.
Brouwers, J. F. H. M., & Gadella, B. M. (2003). In situ detection and localization of lipid peroxidation in individual bovine sperm cells. Relatoin to peroxidation of endogenous phosphatidylcholine and effects of storage. Free Radical Biology and Medicine, 35, 1382-1391.
Rathi, R., Colenbrander, B. A., Stout, T. A. E., Bevers, M. M., & Gadella, B. M. (2003). Progesterone induces acrosome reaction in stallion spermatozoa via a protein tyrosine kinase dependent pathway. Molecular Reproduction and Development, 64(1), 120-128.
Colenbrander, B. A., Gadella, B. M., & Stout, T. A. E. (2003). The predictive value of semen analysis in the evaluation of stallion fertility. Reproduction in Domestic Animals, 38(4), 305-311.
Overige resultaten
Ruonala, M. O., van den Heuvel, D. J., Gadella, B. M., Verkleij, A. J., Gerritsen, H. C., & van Bergen en Henegouwen, P. M. P. (2003). The high affinity EGF receptor is present in lipid rafts. Abstract from Unknown event, Asilomar, USA.
2002
Wetenschappelijke publicaties
Dieleman, S. J., Hendriksen, P. J. M., Viuff, D., Hyttel, P., Knijn, H. M., Wrenzycki, C., Kruip, T. A. M., Niemann, H., Gadella, B. M., Bevers, M. M., & Vos, P. L. A. M. (2002). Effects of in vivo prematuration and in vivo final maturation on developmental capacity and quality of pre-implantation embryo's. Theriogenology, 57, 5-20.
Nield, D. M., Gadella, B. M., Colenbrander, B. A., Aguero, A., & Brouwers, J. F. H. M. (2002). Lipid peroxidation in stallion spermatozoa. In Proc. 8th Intern. Symp. Equine Reprod. (pp. 295-298).
Gadella, B. M. (2002). Bicarbonate's role in mammalian sperm capacitation. In van der Horst, Franken, Bornman, Fazelius, & Dyer (Eds.), Proceedings of the 9th International Symposium on Spermatology (pp. 101-108). Menduzzit Editore S.p.A.- Medicon Inc..
Rathi, R., Colenbrander, B. A., Stout, T. A. E., Bevers, M. M., & Gadella, B. M. (2002). Progesterone induces acrosome reaction in stallion spermatozoa via a protein tyrosine kinase dependent pathway. In Proc. 8th Intern. Symp. Equine Reprod. (pp. 307-311).
Gadella, B. M., & Harrison, R. A. P. (2002). Capacitation induces cyclic adenosine 3', 5'-monophosphate-dependent, but apoptosis-unrelated, exposure of aminophospholipids at the apical head plasma membrane of boar sperm cells. Biology of Reproduction, 67(1), 340-350.
Colenbrander, B. A., Brouwers, J. F. H. M., Nield, D. M., Stout, T. A. E., Da Silva, P., & Gadella, B. M. (2002). Capacitation dependent lipid rearrangements in the plasma membrane of equine sperm. In Proc. 8th Intern. Symp. Equine Reprod. (pp. 341-345).
Vakpublicaties
Gadella, B. M., van Haeften, T., van Bavel, K., & Valentijn, J. A. (2002). Multi-photon excitation microscopy for advanced biomedical imaging. Veterinary Sciences Tomorrow, 4, 1-17.
2001
Wetenschappelijke publicaties
Flesch, F. M., Brouwers, J. F. H. M., Nievelstein, P. F. E. M., Verkleij, A. J., van Golde, L. M. G., Colenbrander, B. A., & Gadella, B. M. (2001). Bicarbonate stimulated phospholipid scrambling induces cholesterol redistribution and enables cholesterol depletion in the sperm plasma membrane. Journal of Cell Science, 114, 3543-3555.
ten Brinke, A. J., Batenburg, J. J., Gadella, B. M., Haagsman, H. P., Vaandrager, A. B., & van Golde, L. M. G. (2001). The juxtamembrane lysine and arginine residues of surfactant protein C precursor influence palmitoylation via effects on trafficking. American Journal of Respiratory Cell and Molecular Biology, 25, 156-163.
Sirivaidyapong, S., Bevers, M. M., Gadella, B. M., & Colenbrander, B. A. (2001). The generation of the acrosome reaction in the dog sperm cells is dependent on epididymal maturation. The generation of a functional progesterone receptor is involved. Molecular Reproduction and Development, 58, 451-459.
Colenbrander, B. A., Rathi, R., Stout, T. A. E., & Gadella, B. M. (2001). Stallion fertility: clinical and fundamental aspects. In Proceedings 3rd Congres Iberico de Reprodução Animal (pp. 133-139)
Rathi, R., Colenbrander, B. A., Bevers, M. M., & Gadella, B. M. (2001). Evaluation of in vitro capacitation of stallion spermatozoa. Biology of Reproduction, 65, 462-470.
Flesch, F. M., Wijnand, E., van de Lest, C. H. A., Colenbrander, B. A., van Golde, L. M. G., & Gadella, B. M. (2001). Capacitation dependent activation of tyrosine phosphorylation generates two sperm head plasma membrane proteins with high primary binding affinity for the zona pellucida. Molecular Reproduction and Development, 60, 107-115.
Rathi, R., Colenbrander, B. A., Bevers, M. M., & Gadella, B. M. (2001). Comparison of anterior-posterior development in the porcine versus the chicken embryo, using goosecoid expression as a marker. Biology of Reproduction, 65, 462-470.
Sirivaidyapong, S., Bevers, M. M., Gadella, B. M., & Colenbrander, B. A. (2001). Induction of the acrosome reaction in dog sperm cells is dependent on epididymal maturation: The generation of a functional progesterone receptor is involved. Molecular Reproduction and Development, 58, 451-459.
Gadella, B. M., Rathi, R., Brouwers, J. F. H. M., Stout, T. A. E., & Colenbrander, B. A. (2001). Capacitation and the acrosome reaction in equine sperm. Animal Reproduction Science, 68(3-4), 249-265.
2000
Wetenschappelijke publicaties
Colenbrander, B. A., Gadella, B. M., Feitsma, H. M., & Woelders, H. (2000). Semen quality evaluation, present and future. In L. A. Johnson, & H. D. Guthrie (Eds.), Boar Semen Preservation IV (pp. 35-41). Allen Press Inc..
Revah, I., Gadella, B. M., Flesch, F. M., & Colenbrander, B. A. (2000). Physiological state of bull sperm affects fucose- and mannose-binding properties. Biology of Reproduction, 62, 1010-1015.
Revah, I., Gadella, B. M., Flesch, F. M., Colenbrander, B. A., & Suarez, S. S. (2000). The physiological state of bull sperm affect fructose en mannose-binding properties. Biology of Reproduction, 62, 1010-1015.
Colenbrander, B. A., Rathi, R., Bevers, M. M., & Gadella, B. M. (2000). Induction of the acrosome reaction by progesterone binding to a non-genomic receptor exposed on the apical plasma membrane of capacitated sperm cells. Havemeyer Foundation Monograph Series, 1, 3-4.
Flesch, F. M., Colenbrander, B. A., van Golde, L. M. G., & Gadella, B. M. (2000). Capacitation induced molecular alterations in the plasma membrane of boar spermatozoa in relation to zona affinity. In L. A. Johnson, & H. D. Guthrie (Eds.), Boar Semen Preservation IV (pp. 21-31). Allen Press Inc..
Szász, F., Sirivaidyapong, S., Cheng, F. P., Voorhout, W. F., Marks, A., Colenbrander, B. A., Solt, L., & Gadella, B. M. (2000). Detection of calcium ionophore induced membrane changes in dog sperm as a simple method to predict the cryopreservability of dog semen. Molecular Reproduction and Development, 55, 289-298.
Flesch, F. M., & Gadella, B. M. (2000). Dynamics of the mammalian sperm membrane in the process of fertilization. Biochimica et Biophysica Acta, 469(3), 197-235.
White, D., Weerachatyanukul, W., Gadella, B. M., Kamolvarin, N., Attar, M., & Tanphaichitr, N. (2000). Role of sperm sulfogalactosylglycerolipid in mouse sperm-zona pellucida binding. Biology of Reproduction, 63, 147-155.
Gadella, B. M., & Harrison, R. A. P. (2000). The capacitating agent bicarbonate induces protein kinase A-dependent changes in phospholipid transbilayer behavior in the plasmamemebrane. Development (Cambridge, England), 127, 2407-2420.
1999
Wetenschappelijke publicaties
't Hart, H., van Ham, R. D. H. J., Stevens, J. F., Elema, E. T., van der Klis, H., & Gadella, B. M. (1999). Biosystematic, molecular and phytochemical evidence for the multiple origin of sympetaly in Eurasian Sedoiceae (Crassulaceae). Biochemical Systematics and Evolution, 27, 407-426.
1998
Wetenschappelijke publicaties
Brouwers, J. F., Gadella, B. M., van Golde, L. M., & Tielens, A. G. (1998). Quantitative analysis of phosphatidylcholine molecular species using HPLC and light scattering detection. Journal of Lipid Research, 39(2), 344-53.