Publications
2025
Scholarly publications
Palmieri, F., Gueye, M., Vicario Del Rio, L., Bunschuh, S., Chopra, P., Mihăilă, S., Vermonden, T., Levato, R., & Boons, G.-J. (2025). Photo-triggered Hyaluronic Acid Hydrogel for 3D Culture and Cell Recovery. ChemBioChem, Article e202500310. Advance online publication. [DOI]
Ahmed, S., Sparidans, R. W., Vernooij, R. W. M., Mihaila, S. M., Broekhuizen, R., Goldschmeding, R., Nguyen, T. Q., Masereeuw, R., & Gerritsen, K. G. F. (2025). Protein-bound uremic toxin clearance as biomarker of kidney tubular function in diabetic kidney disease. Scientific Reports, 15(1), Article 23406. [DOI] [Portal]
Ahmed, S., Chen, S., Lucas, J. P. F. E., Knoppert, S. N., Harwood, R., Faria, J., Besseling, P. J., Sparidans, R. W., Broekhuizen, R., Westphal, K. G. C., Mihăilă, S. M., Joles, J. A., Goldschmeding, R., Nguyen, T. Q., Wilm, B., Murray, P., Sonnen, A. F.-P., Gerritsen, K. G. F., & Masereeuw, R. (2025). Indoxyl sulfate as a potential tubular function marker across kidney disease models. American Journal of Physiology - Renal Physiology, 329(1), F160-F177. [DOI] [Portal]
Di Marco, G., Falandt, M., Neumann, M., Viola, M., Sampon, T., Valverde, M. G., van Genderen, A. M., Mihaila, S. M., van Nostrum, C. F., van Ravensteijn, B. G. P., Levato, R., Masereeuw, R., & Vermonden, T. (2025). Tunable Thermoshrinkable Hydrogels for 4D Fabrication of Cell-Seeded Channels. Advanced Functional Materials. Advance online publication. [DOI]
G Valverde, M., Stampa Zamorano, C., Kožinec, D., Benito Zarza, L., van Genderen, A. M., Janssen, R., Castilho, M., Hrynevich, A., Vermonden, T., Malda, J., de Ruijter, M., Masereeuw, R., & Mihăilă, S. M. (2025). Thermoforming for Small Feature Replication in Melt Electrowritten Membranes to Model Kidney Proximal Tubule. Advanced healthcare materials, 14(1), Article 2401800. [DOI] [Portal]
2024
Scholarly publications
Viola, M., Valverde, M. G., Bernal, P. N., van Trijp, J. P., Hak, J., Marco, G. D., Neumann, M., Schuurmans, C. C. L., van Nostrum, C. F., Masereeuw, R., Mihăilă, S. M., Malda, J., Levato, R., & Vermonden, T. (2024). Thermal Shrinking of Biopolymeric Hydrogels for High Resolution 3D Printing of Kidney Tubules. Advanced Functional Materials, 34(46), Article 2406098. [DOI] [Portal]
Orge, I. D., Nogueira Pinto, H., Silva, M. A., Bidarra, S. J., Ferreira, S. A., Calejo, I., Masereeuw, R., Mihăilă, S. M., & Barrias, C. C. (2024). Vascular units as advanced living materials for bottom-up engineering of perfusable 3D microvascular networks. Bioactive Materials, 38, 499-511. [DOI] [Repository]
2023
Scholarly publications
Faria, J., Calcat-i-Cervera, S., Skovronova, R., Broeksma, B. C., Berends, A. J., Zaal, E. A., Bussolati, B., O’Brien, T., Mihăilă, S. M., & Masereeuw, R. (2023). Mesenchymal stromal cells secretome restores bioenergetic and redox homeostasis in human proximal tubule cells after ischemic injury. Stem cell research & therapy, 14(1), 1-19. Article 353. [DOI] [Repository]
Ahmed, S., Vries, J. C. D., Lu, J., Stuart, M. H. V., Mihăilă, S. M., Vernooij, R. W. M., Masereeuw, R., & Gerritsen, K. G. F. (2023). Animal Models for Studying Protein-Bound Uremic Toxin Removal—A Systematic Review. International Journal of Molecular Sciences, 24(17), Article 13197. [DOI] [Repository]
Faria, J., Ahmed, S., Stamatialis, D., Verhaar, M. C., Masereeuw, R., Gerritsen, K. G. F., & Mihăilă, S. M. (2023). Bioengineered Kidney Tubules Efficiently Clear Uremic Toxins in Experimental Dialysis Conditions. International Journal of Molecular Sciences, 24(15), Article 12435. [DOI] [Repository]
Valibeknejad, M., Abdoli, S. M., Alizadeh, R., Mihăilă, S. M., & Raoof, A. (2023). Insights into transport in mucus barrier: Exploring particle penetration through the intestinal mucus layer. Journal of Drug Delivery Science and Technology, 86, 1-10. Article 104752. [DOI] [Repository]
Ramada, D. L., de Vries, J., Vollenbroek, J., Noor, N., Ter Beek, O., Mihaila, S., Wieringa, F., Masereeuw, R., Gerritsen, K. G. F., & Stamatialis, D. (2023). Portable, wearable and implantable artificial kidney systems: needs, opportunities and challenges. Nature Reviews Nephrology, 19(8), 481-490. [DOI] [Repository]
2022
Scholarly publications
Lacueva-Aparicio, A., Soares Lindoso, R., Mihaila, S., & Giménez, I. (2022). Role of extracellular matrix components and structure in new renal models in vitro. Frontiers in Physiology, 13, 1-14. Article 1048738. [DOI] [Repository]
Favero, C., Giordano, L., Mihaila, S. M., Masereeuw, R., Ortiz, A., & Sanchez-Niño, M. D. (2022). Postbiotics and Kidney Disease. Toxins, 14(9), 1-17. Article 623. [DOI] [Repository]
Genderen, A. M. V., G Valverde, M., Capendale, P. E., Kersten, V., Sendino Garví, E., Schuurmans, C. C. L., Ruelas, M., Soeiro, J. T., Tang, G., Janssen, M. J., Jansen, J., Mihăilă, S. M., Vermonden, T., Zhang, Y. S., & Masereeuw, R. (2022). Co-axial Printing of Convoluted Proximal Tubule for Kidney Disease Modeling. Biofabrication, 14(4), 1-16. Article 044102. [DOI] [Repository]
García Valverde, M., Ferreira Faria, J., Sendino Garví, E., Janssen, M. J., Masereeuw, R., & Mihaila, S. (2022). Organs-on-chip technology: a tool to tackle genetic kidney diseases. Pediatric Nephrology, 37(12), 2985-2996. [DOI] [Repository]
Ahmed, S., Sparidans, R. W., Lu, J., Mihaila, S. M., Gerritsen, K. G. F., & Masereeuw, R. (2022). A robust, accurate, sensitive LC-MS/MS method to measure indoxyl sulfate, validated for plasma and kidney cells. Biomedical Chromatography, 36(5), 1-10. Article e5307. [DOI] [Repository]
2021
Scholarly publications
King, J., Mihaila, S. M., Ahmed, S., Truckenmüller, R., Giselbrecht, S., Masereeuw, R., & Carlier, A. (2021). The Influence of OAT1 Density and Functionality on Indoxyl Sulfate Transport in the Human Proximal Tubule: An Integrated Computational and In Vitro Study. Toxins, 13(10), 1-19. Article 674. [DOI] [Repository]
Faria, J., Gerritsen, K. G. F., Nguyen, T. Q., Mihaila, S. M., & Masereeuw, R. (2021). Diabetic proximal tubulopathy: Can we mimic the disease for in vitro screening of SGLT inhibitors? European Journal of Pharmacology, 908, 1-11. Article 174378. [DOI] [Repository]
Giordano, L., Mihaila, S. M., Eslami Amirabadi, H., & Masereeuw, R. (2021). Microphysiological Systems to Recapitulate the Gut–Kidney Axis. Trends in Biotechnology, 39(8), 811-823. [DOI] [Repository]
2020
Scholarly publications
Pot, M. W., Mihaila, S. M., Te Brinke, D., van der Borg, G., Oosterwijk, E., Daamen, W. F., & van Kuppevelt, T. H. (2020). Introduction of Specific 3D Micromorphologies in Collagen Scaffolds Using Odd and Even Dicarboxylic Acids. ACS Omega, 5(8), 3908-3916. [DOI] [Repository]
Liu, K., Veenendaal, T., Wiendels, M., Ruiz-Zapata, A. M., van Laar, J., Kyranas, R., Enting, H., van Cranenbroek, B., Koenen, H. J. P. M., Mihaila, S. M., Oosterwijk, E., & Kouwer, P. H. J. (2020). Synthetic Extracellular Matrices as a Toolbox to Tune Stem Cell Secretome. ACS applied materials & interfaces, 12(51), 56723-56730. [DOI] [Repository]
Mihaila, S. M., Faria, J., Stefens, M. F. J., Stamatialis, D., Verhaar, M. C., Gerritsen, K. G. F., & Masereeuw, R. (2020). Drugs commonly applied to kidney patients may compromise renal tubular uremic toxins excretion. Toxins, 12(6), Article 391. [DOI] [Repository]
2019
Scholarly publications
Liu, K., Mihaila, S. M., Rowan, A., Oosterwijk, E., & Kouwer, P. H. J. (2019). Synthetic Extracellular Matrices with Nonlinear Elasticity Regulate Cellular Organization. Biomacromolecules, 20(2), 826-834. [DOI]
Faria, J., Ahmed, S., Gerritsen, K. G. F., Mihaila, S. M., & Masereeuw, R. (2019). Kidney-based in vitro models for drug-induced toxicity testing. Archives of Toxicology, 93, 3397–3418. [DOI] [Repository]
2018
Scholarly publications
Sloff, M., Janke, H. P., de Jonge, P. K. J. D., Tiemessen, D. M., Kortmann, B. B. M., Mihaila, S. M., Geutjes, P. J., Feitz, W. F. J., & Oosterwijk, E. (2018). The Impact of γ-Irradiation and EtO Degassing on Tissue Remodeling of Collagen-based Hybrid Tubular Templates. ACS Biomaterials Science and Engineering, 4(9), 3282-3290. [DOI]
van Gelder, M. K., Mihaila, S. M., Jansen, J., Wester, M., Verhaar, M. C., Joles, J. A., Stamatialis, D., Masereeuw, R., & Gerritsen, K. G. F. (2018). From portable dialysis to a bioengineered kidney. Expert Review of Medical Devices, 15(5), 323-336. [DOI] [Repository]
2017
Scholarly publications
Janke, H. P., Bohlin, J., Lomme, R. M. L. M., Mihaila, S. M., Hilborn, J., Feitz, W. F. J., & Oosterwijk, E. (2017). Bioinspired coupled helical coils for soft tissue engineering of tubular structures: Improved mechanical behavior of tubular collagen type I templates. Acta Biomaterialia, 59, 234-242. [DOI]
Mihaila, S. M., Resende, M. F., Reis, R. L., Gomes, M. E., & Marques, A. P. (2017). Interactive endothelial phenotype maintenance and osteogenic differentiation of adipose tissue stromal vascular fraction SSEA-4+ -derived cells. Journal of Tissue Engineering and Regenerative Medicine, 11(7), 1998-2013. [DOI]
2014
Scholarly publications
Mihaila, S. M., Gaharwar, A. K., Reis, R. L., Khademhosseini, A., Marques, A. P., & Gomes, M. E. (2014). The osteogenic differentiation of SSEA-4 sub-population of human adipose derived stem cells using silicate nanoplatelets. Biomaterials, 35(33), 9087-99. [DOI]
Gaharwar, A. K., Mihaila, S. M., Kulkarni, A. A., Patel, A., Di Luca, A., Reis, R. L., Gomes, M. E., van Blitterswijk, C., Moroni, L., & Khademhosseini, A. (2014). Amphiphilic beads as depots for sustained drug release integrated into fibrillar scaffolds. Journal of controlled release : official journal of the Controlled Release Society, 187, 66-73. [DOI]
Gaharwar, A. K., Mukundan, S., Karaca, E., Dolatshahi-Pirouz, A., Patel, A., Rangarajan, K., Mihaila, S. M., Iviglia, G., Zhang, H., & Khademhosseini, A. (2014). Nanoclay-enriched poly(ɛ-caprolactone) electrospun scaffolds for osteogenic differentiation of human mesenchymal stem cells. Tissue Engineering. Part A, 20(15-16), 2088-101. [DOI]
Mihaila, S. M., Popa, E. G., Reis, R. L., Marques, A. P., & Gomes, M. E. (2014). Fabrication of endothelial cell-laden carrageenan microfibers for microvascularized bone tissue engineering applications. Biomacromolecules, 15(8), 2849-60. [DOI]
2013
Scholarly publications
Gaharwar, A. K., Mihaila, S. M., Swami, A., Patel, A., Sant, S., Reis, R. L., Marques, A. P., Gomes, M. E., & Khademhosseini, A. (2013). Bioactive silicate nanoplatelets for osteogenic differentiation of human mesenchymal stem cells. Advanced Materials, 25(24), 3329-36. [DOI]
Patel, A., Gaharwar, A. K., Iviglia, G., Zhang, H., Mukundan, S., Mihaila, S. M., Demarchi, D., & Khademhosseini, A. (2013). Highly elastomeric poly(glycerol sebacate)-co-poly(ethylene glycol) amphiphilic block copolymers. Biomaterials, 34(16), 3970-3983. [DOI]
Zhang, H., Patel, A., Gaharwar, A. K., Mihaila, S. M., Iviglia, G., Mukundan, S., Bae, H., Yang, H., & Khademhosseini, A. (2013). Hyperbranched polyester hydrogels with controlled drug release and cell adhesion properties. Biomacromolecules, 14(5), 1299-310. [DOI]
Mihaila, S. M., Frias, A. M., Pirraco, R. P., Rada, T., Reis, R. L., Gomes, M. E., & Marques, A. P. (2013). Human adipose tissue-derived SSEA-4 subpopulation multi-differentiation potential towards the endothelial and osteogenic lineages. Tissue Engineering. Part A, 19(1-2), 235-46. [DOI]
Mihaila, S. M., Gaharwar, A. K., Reis, R. L., Marques, A. P., Gomes, M. E., & Khademhosseini, A. (2013). Photocrosslinkable kappa-carrageenan hydrogels for tissue engineering applications. Advanced healthcare materials, 2(6), 895-907. [DOI]