Dr. S.J.E. (Saskia) Suijkerbuijk

Hugo R. Kruytgebouw
Padualaan 8
Kamer O.506
3584 CH Utrecht

Dr. S.J.E. (Saskia) Suijkerbuijk

Assistant Professor
Developmental Biology
+31 30 253 2035
s.j.e.suijkerbuijk@uu.nl

Publications

2022

Scholarly publications

Silva, J., Alkan, F., Ramalho, S., Snieckute, G., Prekovic, S., Garcia, A. K., Hernández-Pérez, S., Kammen, R. V. D., Barnum, D., Hoekman, L., Altelaar, M., Zwart, W., Suijkerbuijk, S. J. E., Bekker-Jensen, S., & Faller, W. J. (2022). Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation. Nature Communications. https://doi.org/10.1038/s41467-022-32220-4

2021

Scholarly publications

Krotenberg Garcia, A., van Rheenen, J., & Suijkerbuijk, S. (2021). Generation of mixed murine organoids to model cellular interactions. STAR Protocols. https://doi.org/10.1016/j.xpro.2021.100997

2020

Scholarly publications

Fumagalli, A., Oost, K., Kester, L., Morgner, J., Bornes, L., Bruens, L., Spaargaren, L., Azkanaz, M., Schelfhorst, T., Beerling, E., Heinz, M., Postrach, D., Seinstra, D., Sieuwerts, A., Martens, J., van der Elst, S., van Baalen, M., Bhowmick, D., Vrisekoop, N., ... van Rheenen, J. (2020). Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer. Cell Stem Cell. https://doi.org/10.1016/j.stem.2020.02.008
Bruens, L., Ellenbroek, S. I. J., Suijkerbuijk, S. J. E., Azkanaz, M., Hale, A. J., Toonen, P., Flanagan, D. J., Sansom, O. J., Snippert, H. J., & Rheenen, J. V. (2020). Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine. Cell Reports. https://doi.org/10.1016/j.celrep.2020.107937
Garcia, A. K., Fumagalli, A., Le, H. Q., Sansom, O. J., Rheenen, J. V., & Suijkerbuijk, S. J. E. (2020). Active elimination of intestinal cells drives oncogenic growth in organoids. Cell Reports. https://doi.org/10.1101/2020.11.14.378588

2018

Scholarly publications

Fumagalli, A., Suijkerbuijk, S. J. E., Begthel, H., Beerling, E., Oost, K. C., Snippert, H. J., Rheenen, J. V., & Drost, J. (2018). A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression. Nature Protocols. https://doi.org/10.1038/nprot.2017.137

2017

Scholarly publications

Fumagalli, A., Drost, J., Suijkerbuijk, S. J. E., Van Boxtel, R., De Ligt, J., Offerhaus, G. J., Begthel, H., Beerling, E., Tan, E. H., Sansom, O. J., Cuppen, E., Clevers, H., & Van Rheenen, J. (2017). Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids. Proceedings of the National Academy of Sciences of the United States of America. https://doi.org/10.1073/pnas.1701219114
Suijkerbuijk, S., & van Rheenen, J. (2017). From good to bad: Intravital imaging of the hijack of physiological processes by cancer cells. Developmental Biology. https://doi.org/10.1016/j.ydbio.2017.04.015

2016

Scholarly publications

Suijkerbuijk, S. J. E., Kolahgar, G., Kucinski, I., & Piddini, E. (2016). Cell competition drives the growth of intestinal adenomas in Drosophila. Current Biology. https://doi.org/10.1016/j.cub.2015.12.043