dr. R. (Reinout) Raijmakers
Gegenereerd op 2017-11-23 17:38:08


Reinout Raijmakers is the teamleader of the Research Support Office at the Science Faculty of Utrecht University and the Managing Director of the Bijvoet Center for Biomolecular Research.

The Research Support Office assists researchers in identifying potential funds, provides advice on national and international grant opportunities and supports researchers in writing grant applications.

Within the Bijvoet Center he is responsible for the coordination of EU funded research and infrastructure projects and provides the staff with support in preparing grant applications. He is also responsbile for the organization the educational programme for the students in the center, which includes courses, a seminar series and a yearly symposium. Before becoming the Managing Director of the center, he has been working as a scientist on the analysis of post-translational modifications and interactions of proteins and their relation with disease, with an emphasis on their analysis by liquid chromatography and mass spectrometry.

Strategic themes / Focus areas
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Curriculum vitae

Reinout Raijmakers is the teamleader of the Research Support Office at the Science Faculty of Utrecht University and the Managing Director of the Bijvoet Center for Biomolecular Research.

Highlights of awarded research projects in which Reinout Raijmakers has been involved in the project management and/or grant application:

Reinout did his PhD at the department of Biochemistry of the University of Nijmegen, where he studied the function and structure of the human exosome complex. After receiving his PhD he started work on the role of post-translational modifications of central nervous system proteins in the development of multiple sclerosis and other autoimmune diseases. After moving to Utrecht University, he worked as a junior UD on the development of methods to use chip-based liquid chromatography and mass spectrometry to analyze post-translationally modified peptides and proteins (including phosphorylation and citrullination) and to study protein complex composition, structure and diversity, in a collaboration with the company Agilent Technologies. As a “Hotel Manager” for the Netherlands Proteomics Centre, he collaborated with many (inter-)national research groups to address a wide variety of research questions with, mass spectrometry based, proteomics technology. In 2010, he became Managing Director of the Bijvoet Center for Biomolecular Research at Utrecht University.

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A full list of my publications can be found at my ResearcherID.

All publications
  2014 - Scholarly publications
Raijmakers, Reinout, Olsen, Jesper V, Aebersold, Ruedi & Heck, Albert J R (2014). PRIME-XS, a European infrastructure for proteomics. Molecular and Cellular Proteomics, 13 (8), (pp. 1901-4) (4 p.). © 2014 by The American Society for Biochemistry and Molecular Biology, Inc..
  2013 - Scholarly publications
Haberkant, P., Raijmakers, R., Wildwater, M., Sachsenheimer, T., Brügger, B., Maeda, K., Houweling, M., Gavin, A-C, Schultz, C., van Meer, G., Heck, A.J.R. & Holthuis, J.C.M. (2013). In vivo profiling and visualization of cellular protein–lipid interactions using bifunctional fatty acids. Angewandte Chemie-International Edition, 52, (pp. 4033-4038) (6 p.).
  2012 - Scholarly publications
Kovanich, D., Cappadona, S., Raijmakers, R., Mohammed, S., Scholten, A. & Heck, A.J.R. (2012). Applications of stable isotope dimethyl labeling in quantitative proteomics. Fresenius Zeitschrift fur Analytische Chemie, 404 (4), (pp. 991-1009) (19 p.).
Bleijerveld, O.B., Wijten, P., Cappadona, S., McClellan, E.A., Polat, A.N., Raijmakers, R., Sels, J.W., Colle, L.B., Grasso, S., van den Toorn, H.W.P., van Breukelen, B., Stubbs, A., Pasterkamp, G., Heck, A.J.R., Hoefer, I.E. & Scholten, A. (2012). Deep Proteome Profiling of Circulating Granulocytes Reveals Bactericidal/Permeability-Increasing Protein as a Biomarker for Severe Atherosclerotic Coronary Stenosis. Journal of Proteome Research, 11, (pp. 5235-5244) (10 p.).
Raijmakers, R., Beers, J.J.B.C., El-Azzouny, M., Visser, N.F.C., Bozic, B., Pruijn, G.J.M. & Heck, A.J.R. (2012). Elevated levels of fibrinogen-derived endogenous citrullinated peptides in synovial fluid of rheumatoid arthritis patients. Arthritis Research and Therapy, 14.
Polat, A.N., Kraiczek, K., Heck, A.J.R., Raijmakers, R. & Mohammed, S. (2012). Fully automated isotopic dimethyl labeling and phosphopeptide enrichment using a microfluidic HPLC phosphochip. Fresenius Zeitschrift fur Analytische Chemie, 404, (pp. 2507-2512) (6 p.).
  2011 - Scholarly publications
Di Palma, S., Raijmakers, R., Heck, A.J.R. & Mohammed, S. (2011). Evaluation of the deuterium isotope effect in zwitterionic hydrophilic interaction liquid chromatography separations for implementation in a quantitative proteomic approach. Analytical Chemistry, 83 (21), (pp. 8352-8356) (5 p.).
van Dooren, S.H., Raijmakers, R., Pluk, H., Lokate, A.M.C., Koemans, T.S., Spanjers, R.E., Heck, A.J.R., Boelens, W.C., van Venrooij, W.J. & Pruijn, G.J.M. (2011). Oxidative stress-induced modifications of histidyl-tRNA synthetase affect its tRNA aminoacylation activity but not its immunoreactivity. Biochemistry and Cell Biology, 89 (6), (pp. 545-553) (9 p.).
van den Toorn, H.W.P., Munoz, J, Mohammed, S., Raijmakers, R., Heck, A.J.R. & van Breukelen, B. (2011). RockerBox: analysis and filtering of massive proteomics search results. Journal of Proteome Research, 10 (3), (pp. 1420-1424) (5 p.).
Snijder, J., Rose, R.J., Raijmakers, R. & Heck, A.J.R. (2011). Site-specific methionine oxidation in calmodulin affects structural integrity and interaction with Ca2+/calmodulin-dependent protein kinase II. Journal of Structural Biology, 174 (1), (pp. 187-195) (9 p.).
  2010 - Scholarly publications
Raijmakers, R., Neerincx, P.B.T., Mohammed, S. & Heck, A.J.R. (2010). Cleavage specificities of the brother and sister proteases Lys-C and Lys-N. Chemical Communications, 46, (pp. 8827-8829) (3 p.).
Staals, R.H.J, Bronkhorst, A.W., Schilders, G., Slomovic, S., Schuster, G., Heck, A.J.R., Raijmakers, R. & Pruijn, G.J.M. (2010). Dis3-like 1: a novel exoribonuclease associated with the human exosome. EMBO Journal, 29 (14), (pp. 2358-2367) (10 p.).
Raijmakers, R., Kraiczek, K., de Jong, A.P., Mohammed, S. & Heck, A.J.R. (2010). Exploring the human leukocyte phosphoproteome using a microfluidic reversed-phase-TiO2-reversed-phase high-performance liquid chromatography phosphochip coupled to a quadrupole time-of-flight mass spectrometer. Analytical Chemistry, 82 (3), (pp. 824-832) (9 p.).
van Beers, J.B.C., Raijmakers, R., Alexander, L-E, Stammen-Vogelzangs, J., Lokate, A.M.C., Heck, A.J.R., Schasfoort, R.B.M. & Pruijn, G.J.M. (2010). Mapping of citrullinated fibrinogen B-cell epitopes in rheumatoid arthritis by imaging surface plasmon resonance. Arthritis Research and Therapy, 12 (6).
Helbig, A.O., Gauci, S., Raijmakers, R., van Breukelen, B., Slijper, M., Mohammed, S. & Heck, A.J.R. (2010). Profiling of N-acetylated protein termini provides in-depth insights into the N-terminal nature of the proteome. Molecular and Cellular Proteomics, 9, (pp. 928-939) (12 p.).
Pelletier, S., Schuurman, K.G., Berkers, C.R., Ovaa, H., Heck, A.J.R. & Raijmakers, R. (2010). Quantifying cross-tissue diversity in proteasome complexes by mass spectrometry. Molecular BioSystems, 6, (pp. 1450-1453) (4 p.).
Raijmakers, R., Pelletier, S., Gouw, J.W., Rumpel, K., Heck, A.J.R. & Dadvar, P. (2010). Target profiling of a small library of phosphodiesterase 5 (PDE5) inhibitors using chemical proteomics. ChemMedChem, 5, (pp. 1927-1936) (10 p.).
  2009 - Scholarly publications
Raijmakers, R., Heck, A.J.R. & Mohammed, S. (2009). Assessing biological variation and protein processing in primary human leukocytes by automated multiplex stable isotope labeling coupled to 2 dimensional peptide separation. Molecular BioSystems (5), (pp. 992-1003) (12 p.).
Synowsky, S.A., van Wijk, M., Raijmakers, R. & Heck, A.J.R. (2009). Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes. Journal of Molecular Biology (385), (pp. 1300-1313) (14 p.).
Boersema, P.J., Raijmakers, R., Lemeer, S.M., Mohammed, S. & Heck, A.J.R. (2009). Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics. Nature Protocols (4), (pp. 484-494) (11 p.).
Dadvar, P., Kovanich, D., Folkers, G.E., Rumpel, K., Raijmakers, R. & Heck, A.J.R. (2009). Phosphatidylethanolamine-binding proteins, including RKIP, exhibit affinity for phosphodiesterase-5 inhibitors. ChemBioChem (10), (pp. 2654-2662) (9 p.).
  2008 - Scholarly publications
Raijmakers, R., Berkers, C.R., de Jong, G.J., Ovaa, H., Heck, A.J.R. & Mohammed, S. (2008). Automated online sequential isotope labeling for protein quantitation applied to proteasome tissue specific diversity. Molecular and Cellular Proteomics, 7, (pp. 1755-1762) (8 p.).
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Gegenereerd op 2017-11-23 17:38:08
Full name
dr. R. Raijmakers Contact details
Postal address
Padualaan 8
3584 CH    UTRECHT
The Netherlands
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Contact Details

Hans Freudenthalgebouw
Budapestlaan 6
Room 004
The Netherlands
Phone number (direct) +31 30 253 2641

Hugo R. Kruytgebouw
Padualaan 8
Room O604
The Netherlands
Phone number (direct) +31 30 253 6804


Gegenereerd op 2017-11-23 17:38:08
Last updated 24.08.2017