Publications
2024
Scholarly publications
Luteijn, R. D., & van Kuppeveld, F. J. M. (2024). Author Correction: Rhinoviruses usurp STING for replication. Nature Microbiology. Advance online publication. https://doi.org/10.1038/s41564-024-01689-8
Luteijn, R. D., van Terwisga, S. R., Ver Eecke, J. E., Onia, L., Zaver, S. A., Woodward, J. J., Wubbolts, R. W., Raulet, D. H., & van Kuppeveld, F. J. M. (2024). The activation of the adaptor protein STING depends on its interactions with the phospholipid PI4P. Science Signaling, 17(827), Article eade3643. https://doi.org/10.1126/scisignal.ade3643
2022
Scholarly publications
Luteijn, R. D., & van Kuppeveld, F. J. M. (2022). Rhinoviruses usurp STING for replication. Nature Microbiology, 7(5), 605-606. https://doi.org/10.1038/s41564-022-01117-9
2020
Scholarly publications
Luteijn, R. D., Praest, P., Thiele, F., Sadasivam, S. M., Singethan, K., Drijfhout, J. W., Bach, C., de Boer, S. M., Lebbink, R. J., Tao, S., Helfer, M., Bach, N. C., Protzer, U., Costa, A. I., Killian, J. A., Drexler, I., & Wiertz, E. J. H. J. (2020). A Broad-Spectrum Antiviral Peptide Blocks Infection of Viruses by Binding to Phosphatidylserine in the Viral Envelope. Cells, 9(9), Article 1989. https://doi.org/10.3390/cells9091989
https://dspace.library.uu.nl/bitstream/handle/1874/411045/cells_09_01989.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/411045/cells_09_01989.pdf?sequence=1
2019
Scholarly publications
Wąchalska, M., Graul, M., Praest, P., Luteijn, R. D., Babnis, A. W., Wiertz, E. J. H. J., Bieńkowska-Szewczyk, K., & Lipińska, A. D. (2019). Fluorescent TAP as a Platform for Virus-Induced Degradation of the Antigenic Peptide Transporter. Cells, 8(12). https://doi.org/10.3390/cells8121590
Luteijn, R. D., van Diemen, F., Blomen, V. A., Boer, I. G. J., Manikam Sadasivam, S., van Kuppevelt, T. H., Drexler, I., Brummelkamp, T. R., Lebbink, R. J., & Wiertz, E. J. (2019). A Genome-Wide Haploid Genetic Screen Identifies Heparan Sulfate-Associated Genes and the Macropinocytosis Modulator TMED10 as Factors Supporting Vaccinia Virus Infection. Journal of Virology, 93(13). https://doi.org/10.1128/JVI.02160-18
Luteijn, R. D., Zaver, S. A., Gowen, B. G., Wyman, S. K., Garelis, N. E., Onia, L., McWhirter, S. M., Katibah, G. E., Corn, J. E., Woodward, J. J., & Raulet, D. H. (2019). SLC19A1 transports immunoreactive cyclic dinucleotides. Nature, 573(7774), 434-438. https://doi.org/10.1038/s41586-019-1553-0
2018
Scholarly publications
Praest, P., Luteijn, R. D., Brak-Boer, I. G. J., Lanfermeijer, J., Hoelen, H., Ijgosse, L., Costa, A. I., Gorham, R. D., Lebbink, R. J., & Wiertz, E. J. H. J. (2018). The influence of TAP1 and TAP2 gene polymorphisms on TAP function and its inhibition by viral immune evasion proteins. Molecular Immunology, 101, 55-64. https://doi.org/10.1016/j.molimm.2018.05.025
Luteijn, R. D., Drexler, I., Smith, G. L., Lebbink, R. J., & Wiertz, E. J. H. J. (2018). Mutagenic repair of double-stranded DNA breaks in vaccinia virus genomes requires cellular DNA ligase IV activity in the cytosol. Journal of General Virology, 99(6), 790-804. https://doi.org/10.1099/jgv.0.001034
Spel, L., Luteijn, R. D., Drijfhout, J. W., Nierkens, S., Boes, M., & Wiertz, E. J. H. (2018). Endocytosed soluble cowpox virus protein CPXV012 inhibits antigen cross-presentation in human monocyte-derived dendritic cells. Immunology and Cell Biology, 96(2), 137-148. https://doi.org/10.1111/imcb.1024
2016
Scholarly publications
Luteijn, R. D., & Wiertz, E. J. H. J. (2016). Exploiting the exploiter: a viral inhibitor stabilizes TAP for cryo-EM. Nature Structural and Molecular Biology, 23(2), 95-7. https://doi.org/10.1038/nsmb.3168
2015
Scholarly publications
Verweij, M. C., Horst, D., Griffin, B. D., Luteijn, R. D., Davison, A. J., Ressing, M. E., & Wiertz, E. J. H. J. (2015). Viral inhibition of the transporter associated with antigen processing (TAP): a striking example of functional convergent evolution. PLoS Pathogens, 11(4), Article e1004743. https://doi.org/10.1371/journal.ppat.1004743
van de Weijer, M. L., Luteijn, R. D., & Wiertz, E. J. H. J. (2015). Viral immune evasion: Lessons in MHC class I antigen presentation. Seminars in Immunology, 27(2), 125-37. https://doi.org/10.1016/j.smim.2015.03.010
Benedictus, L., Luteijn, R. D., Otten, H., Jan Lebbink, R., van Kooten, P. J. S., Wiertz, E. J. H. J., Rutten, V. P. M. G., & Koets, A. P. (2015). Pathogenicity of Bovine Neonatal Pancytopenia-associated vaccine-induced alloantibodies correlates with Major Histocompatibility Complex class I expression. Scientific Reports, 5, Article 12748. https://doi.org/10.1038/srep12748
2014
Scholarly publications
van de Weijer, M. L., Bassik, M. C., Luteijn, R. D., Voorburg, C. M., Lohuis, M. A. M., Kremmer, E., Hoeben, R. C., LeProust, E. M., Chen, S., Hoelen, H., Ressing, M. E., Patena, W., Weissman, J. S., McManus, M. T., Wiertz, E. J. H. J., & Lebbink, R. J. (2014). A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation. Nature Communications, 5, Article 3832. https://doi.org/10.1038/ncomms4832
2013
Scholarly publications
Ressing, M. E., Luteijn, R. D., Horst, D., & Wiertz, E. J. (2013). Viral interference with antigen presentation: trapping TAP. Molecular Immunology, 55(2), 139-42. https://doi.org/10.1016/j.molimm.2012.10.009
2011
Scholarly publications
Luteijn, R., Sciaranghella, G., van Lunzen, J., Nolting, A., Dugast, A.-S., Ghebremichael, M. S., Altfeld, M., & Alter, G. (2011). Early viral replication in lymph nodes provides HIV with a means by which to escape NK-cell-mediated control. European Journal of Immunology, 41(9), 2729-40. https://doi.org/10.1002/eji.201040886
2010
Scholarly publications
Nolting, A., Dugast, A.-S., Rihn, S., Luteijn, R., Carrington, M. F., Kane, K., Jost, S., Toth, I., Nagami, E., Faetkenheuer, G., Hartmann, P., Altfeld, M., & Alter, G. (2010). MHC class I chain-related protein A shedding in chronic HIV-1 infection is associated with profound NK cell dysfunction. Virology, 406(1), 12-20. https://doi.org/10.1016/j.virol.2010.05.014
Alter, G., Kavanagh, D., Rihn, S., Luteijn, R., Brooks, D., Oldstone, M., van Lunzen, J., & Altfeld, M. (2010). IL-10 induces aberrant deletion of dendritic cells by natural killer cells in the context of HIV infection. Journal of Clinical Investigation, 120(6), 1905-13. https://doi.org/10.1172/JCI40913