Dr. P.V. (Prescilla) Jeurink

Assistant Professor


  • E Looijesteijn, RWW Brouwer, RJW Schoemaker, LH Ulfman, SL Ham, P Jeurink, E Karaglani, WFJ van IJcken, Y Manios. Effect of bovine milk fat-based infant formulae on microbiota, metabolites and stool parameters in healthy term infants in a randomized, crossover, placebo-controlled trial, BMC nutrition, 2022.
  • DM Versluis, R Schoemaker, E Looijesteijn, D Muysken, PV Jeurink, M Paques, JMW Geurts, RMH Merks. A Multiscale Spatiotemporal Model Including a Switch from Aerobic to Anaerobic Metabolism Reproduces Succession in the Early Infant Gut Microbiota, bioRxiv, 2022.
  • J Pereira, LRF Bresser, N van Riel, E Looijesteijn, R Schoemaker, LH Ulfman, P Jeurink, E Karaglani, Y Manios, RWW Brouwer, WFJ van Ijcken, E Levin. Bovine Milk Fat Intervention in Early Life and Its Impact on Microbiota, Metabolites and Clinical Phenotype: A Multi-Omics Stacked Regularization Approach., BioMedInformatics, 2022.


  • BCAM van Esch, JHM van Bilsen, M Gros-van Hest, L Kleinjans, C Belzer, PV Jeurink, J Garssen, JJ Smit, RHH Pieters, LMJ Knippels. A multi-center assessment to compare residual allergenicity of partial hydrolyzed whey proteins in a murine model for cow’s milk allergy–Comparison to the single parameter Toxicology Letters, Volume 333, 15 October 2020, Pages 312-321.
  • P Jochems, J van Bergenhenegouwen, AM van Genderen, S Eis, L Wilod Versprille, H Wichers, P Jeurink, J Garssen and R Masereeuw. P138-Developing a novel 3-dimensional small intestinal-like model for xenobiotic screening. Drug Metabolism and Pharmacokinetics 35 (1), S64-S65.


  • Jeurink PV, Knipping K, Wiens F, Baranska K, Stahl B, Garssen J, Krolak-Olejnik B. Importance of maternal diet in the training of the infant's immune system during gestation and lactation. Crit Rev Food Sci Nutr. 2019.
  • Jochems PGM, van Bergenhenegouwen J, van Genderen AM, Eis ST, Wilod Versprille LJF, Wichers HJ, Jeurink PV, Garssen J, Masereeuw R. Development and validation of bioengineered intestinal tubules for translational research aimed at safety and efficacy testing of drugs and nutrients. Toxicol In Vitro. 2019.
  • Kleinjans L, Veening-Griffioen DH, Wehkamp T, van Bergenhenegouwen J, Knol J, Garssen J, Knippels LMJ, Belzer C, Jeurink PV. Mice co-administrated with partially hydrolysed whey proteins and prebiotic fibre mixtures show allergen-specific tolerance and a modulated gut microbiota. Benef Microbes. 2019.


  • Verheijden KAT, Braber S, Leusink T, Jeurink PV, Thijssen S, Kraneveld AD, Garssen J, Folkerts G, Willemsen LEM. The combination therapy of dietary galacto-oligosaccharides with budesonide reduces pulmonary Th2 driving mediators and mast cell degranulation in a murine model of house dust mite induced asthma. Frontiers in Immunology 2018.
  • Kerperien J, Veening-Griffioen D, Wehkamp T, van Esch BCAM, Hofman GA, Cornelissen P, Boon L, Jeurink PV, Garssen J, Knippels LMJ, Willemsen LEM. IL-10 Receptor or TGF-β Neutralization Abrogates the Protective Effect of a Specific Nondigestible Oligosaccharide Mixture in Cow-Milk-Allergic Mice. J Nutr. Aug 2018.
  • Gouw JW, Jo J, Meulenbroek LAPM, Heijjer TS, Kremer E, Sandalova E, Knulst AC, Jeurink PV, Garssen J, Rijnierse A, Knippels LMJ. Identification of peptides with tolerogenic potential in a hydrolysed whey-based infant formula. Clin Exp Allergy, Oct 2018.
  • Jochems PGM, Garssen J, van Keulen AM, Masereeuw R and Jeurink PV. Evaluating human intestinal cell lines for studying novel proteins absorption. Nutrients, Mar 2018.
  • Kleinjans L, Veening-Griffioen D, Wehkamp T, van Bergenhenegouwen J, Knol J, Garssen J, Knippels LMJ, Belzer C and Jeurink PV. Mice co-administrated with partially hydrolysed whey proteins and prebiotic fiber mixtures show allergen-specific tolerance and a modulated gut microbiota. Beneficial Microbes Dec 2018.


  • Jeurink PV, Damialis A, Wichers H, Savelkoul HFJ. The mutual influences of man-made pollutants and allergic manifestations. APSTRACT 2016.
  • Bol-Schoenmakers M, Braber S, Akbari P, de Graaff P, van Roest M, Kruijssen L, Smit JJ, van Esch ECAM, Jeurink PV, Garssen J, Fink-Gremmels J, and Pieters RHH. The mycotoxin deoxynivalenol facilitates allergic sensitization to whey in mice. Mucosal Immunology, Nov 2016.


  • Difilippo, E, Bettonvil, M, Willems, HAM, Braber, S, Fink-Gremmels-Gehrmann, J, Jeurink PV Schoterman, MHC, Gruppen, H, Schols, HA. Oligosaccharides in urine, blood, and feces of piglets fed a milk replacer containing galacto-oligosaccharides. J Agric Food Chem, 63, Dec 2015.
  • Verheijden KA, Willemsen LE, Braber S, Leusink-Muis T, Jeurink PV, Garssen J, Kraneveld AD, Folkerts G. The development of allergic inflammation in a murine house dust mite asthma model is suppressed by synbiotic mixtures of non-digestible oligosaccharides and Bifidobacterium breve M-16V. Eur J Nutr. 2015 May 24.
  • Koning N, Kessen SF, van der Voorn JP, Appelmelk BJ, Jeurink PV, Knippels LMJ, Garssen J, and van Kooyk Y. Human milk blocks DC-SIGN-pathogen interaction via MUC1. Front. Imm. Mar 2015.


  • Kerperien J, Jeurink PV, Wehkamp T, van der Veer A, van de Kant HJ, Hofman GA, van Esch ECAM, Garssen J, Willemsen LE and Knippels LMJ. Non-digestible oligosaccharides modulate intestinal immune activation and suppress cow’s milk allergic symptoms. Ped. All. Imm., Dec 2014.
  • Jeurink, PV, Meulenbroek, LAPM, Garssen, J & Knippels, LMJ. Allergen Avoidance versus Tolerance Induction. In Pharma-Nutrition; An Overview (pp. 373-391). Cham New York Heidelberg Dordrecht London: Springer.


  • Jeurink PV, van Esch BCAM, Rijnierse A, Martin R, Garssen J, Knippels LMJ. Mechanisms underlying immune effects of dietary oligosaccharides. Am. J. Clin. Nutr., July 2013.
  • van Esch BC, van Bilsen JH, Jeurink PV, Garssen J, Penninks AH, Smit JJ, Pieters RH, Knippels LM. Interlaboratory evaluation of a cow's milk allergy mouse model to assess the allergenicity of hydrolysed cow's milk based infant formulas. Toxicol Lett. 2013 Apr 22;220(1):95-102.
  • Jeurink PV, van Bergenhenegouwen J, Jimenez E, Knippels LMJ, Fernandez L, Garssen J, Knol J, Rodriguez JM, Martin R. Human milk: a source of more life than we imagine. Beneficial Mircobes, 2013 Mar 1;4(1):17-30.


  • Jeurink PV, Rijnierse A, Martin R, Garssen J, Knippels LMJ. Difficulties in describing allergic disease modulation by pre-, pro- and synbiotics. Current pharmaceutical design, 2012, 18, 2369 -2374.


  • Rijnierse A, Jeurink PV, Garssen J, Knippels LM. Food-derived oligosaccharides exhibit pharmaceutical properties. Eur J Pharmacol. 2011 Jul 28.
    van Esch BC, Knipping K, Jeurink P, van der Heide S, Dubois AE, Willemsen LE, Garssen J, Knippels LM. In vivo and in vitro evaluation of the residual allergenicity of partially hydrolysed infant formulas. Toxicol Lett. 2011 Mar 25;201(3):264-9.
  • Nawijn MC, Piavaux BJ, Jeurink PV, Gras R, Reinders MA, Stearns T, Foote S, Hylkema MN, Groot PC, Korstanje R, Oosterhout AJ. Identification of the Mhc region as an asthma susceptibility locus in recombinant congenic mice. Am J Respir Cell Mol Biol. 2011 Aug;45(2):295-303.


  • Mbugi EV, Meijerink M, Veenemans J, Jeurink PV, McCall M, Olomi RM, Shao JF, Chilongola JO, Verhoef H, Savelkoul HF. Effect of nutrient deficiencies on in vitro Th1 and Th2 cytokine response of peripheral blood mononuclear cells to Plasmodium falciparum infection. Malar J. 2010 Jun 14;9:162.
  • Lu Y, Sjöstrand M, Malmhäll C, Rådinger M, Jeurink P, Lötvall J, Bossios A. New production of eosinophils and the corresponding Th1/Th2 balance in the lungs after allergen exposure in BALB/c and C57BL/6 mice. Scand J Immunol. 2010 Mar;71(3):176-85.
  • Mbugi EV, Meijerink M, Veenemans J, Jeurink PV, McCall M, Olomi RM, Shao JF, Verhoef H, Savelkoul HF. Alterations in early cytokine-mediated immune responses to Plasmodium falciparum infection in Tanzanian children with mineral element deficiencies: a cross-sectional survey. Malar J. 2010 May 17;9:130.


  • Jeurink PV, Vissers YM, Rappard B, Savelkoul HFJ. T cell responses in fresh and cryopreserved peripheral blood mononuclear cells: kinetics of cell viability, cellular subsets, proliferation and cytokine production. Cryobiology (2008) Jun 13.
  • Jeurink PV, Lull Noguera C, Savelkoul HFJ, Wichers HJ. Immunomodulatory capacity of fungal proteins on the cytokine production of human peripheral blood mononuclear cells. Int. Immunopharmacology (2008) 8, 1124-1133.


  • Rådinger M, Bossios A, Alm AS, Jeurink P, Lu Y, Malmhäll C, Sjöstrand M, Lötvall J. Regulation of allergen-induced bone marrow eosinophilopoiesis: role of CD4+ and CD8+ T cells. Allergy (2007) 62(12):1410-8.
  • Mandimika T, Baykus H, Vissers Y, Jeurink P, Poortman J, Garza C, Kuiper H, Peijnenburg A. Differential gene expression in intestinal epithelial cells induced by single and mixtures of potato glycoalkaloids. J Agric Food Chem. 2007 Nov 28;55(24):10055-66.
  • Piavaux B, Jeurink PV, Groot PC, Hofman GA, Demant P, Van Oosterhout AJ. Mouse genetic model for antigen-induced airway manifestations of asthma. Genes and Immunity (2007) 8, 28–34.


  • Jeurink PV, Savelkoul HFJ, Induction and regulation of allergen-specific IgE. Allergy matters proceeding book, volume 10, Chapter 2. www.wur.nl/frontis.


  • Vissers JL, van Esch BC, Jeurink PV, Hofman GA, van Oosterhout AJ., Stimulation of allergen-loaded macrophages by TLR9-ligand potentiates IL-10-mediated suppression of allergic airway inflammation in mice. Respir Res. 2004 Nov 11;5(1):21.
  • Jeurink P and Savelkoul H, Cross reactions and food allergies. Voeding Nu, 2004.


  • Van Oosterhout AJ, Jeurink PV, Groot PC, Hofman GA, Nijkamp FP, Demant P., Genetic Analysis of Antigen-Induced Airway Manifestations of Asthma Using Recombinant Congenic Mouse Strains. Chest 2002, 121:13s.