2020- Present | Utrecht University |
Assistant professor, department of Chemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Biomulecular Mass Spectrometry and Proteomics.
2020 | Utrecht University |
Postdoctoral researcher, Biomolecular Mass spectrometry. Advisor: A.J.R. Heck, targeting protein palmitoylation as a possible regulator in neurological diseases (From 02-2020)
2018 – 2019 | The Francis Crick Institute/ Imperial College London |
H2020 Marie Sklodowska-Curie research fellow, secondment in the satellite lab of E.W. Tate, the role of protein lipidation in cancer (from 07/2018-10/2019)
2017 – 2018 | Imperial College London |
H2020 Marie Sklodowska-Curie research Fellow, Chemical Biology Advisor: E.W. Tate, the role of protein lipidation in cancer (07/2017 – 07/2018)
2017 | Leiden University |
Postdoctoral researcher, Molecular Physiology. Advisor: M. van der Stelt, activity-based protein profiling for identification of novel selective serine hydrolase inhibitors (04/2017 – 05/2017)
2012 -2017 Leiden University (Promotion, Cum Laude, April 6, 2017)
Ph.D. Bio-Organic Chemistry under supervision of Prof. Dr. M. van der Stelt and Prof. Dr. H. S. Overkleeft; Thesis title: Activity-based protein profiling of Diacylglycerol lipases
2012 University of Groningen
M.Sc. Organic Chemistry (Graduated on May 31, 2012)
2011 University of Groningen
B.Sc. Organic Chemistry (Graduated on May 31, 2011)
2024 - Vidi, NWO talent programme 2023 (850K) Greasing the Wheels to Understand Protein Lipidation in Inflammation
2023 - NWO-M1 Open competition grant (350K) A greasy protein modification in cancer on the balance
2020 - Veni, NWO talent programme 2020 (250K) Targeting Protein Palmitoylation as a Possible Regulator in Neurological Diseases
2019 - Dutch Medicinal Chemistry prize 2017-2018 (1K) awarded for the best dissertation in the field of medicinal chemistry research published between 1 January 2017 and 31 December 2018.
2017 - H2020 Marie Sklodowska-Curie individual fellowship 2017 (183K) Modulating and profiling receptor tyrosine kinase S-palmitoylation in breast cancer
2016 - International Cannabinoid Research Society (ICRS) travel award (0.5K)
2012 - Unilever research prize 2012 (3.5K) for master thesis entitled “Catalytic asymmetric total synthesis of (S)-(-)-Zearalenone, a novel lipoxygenase inhibitor”
The department of Chemical Physiology, the Scripps research institute, CA, USA
Prof. B. F. Cravatt, Ph.D.
Employed competitive activity-based proteomics to study target engagement and selectivity profiles of DAGL inhibitors in mouse tissues and in situ. In addition, the effect of DAGL inhibitors on substrate and product levels of DAGL was studied in situ and in vivo. (05/2014 – 08/2014)
Bio-organic synthesis, Leiden University, The Netherlands
Prof. Dr. H. S. Overkleeft and Prof. Dr. G. A. van der Marel
Synthesis of a triglycoside that is part of a glycolipid that was isolated from the cell wall of Mycobacterium tuberculosis. (08/2011 - 12/2011)
Bio-organic Chemistry, Groningen University, The Netherlands
Prof. dr. A.J. Minnaard
Catalytic asymmetric synthesis of (S)-(-)-zearalenone using asymmetric allylic alkylation for the introduction of the stereocenter. (S)-(-)-Zearalenone turned out to be a novel lipoxygenase inhibitor. (05/2010 – 06/2011)